Relación entre las habilidades sociales y la agresividad, bajo el contexto de la pandemia COVID-19 en internos de medicina humana de la Universidad Católica de Santa María de Arequipa - 2022

OBJETIVO: Determinar la relación entre las habilidades sociales y la agresividad, bajo el contexto covid-19 en internos de medicina de la Universidad Católica de Santa María de Arequipa, 2022 MÉTODOS: Investigación observacional, cuantitativa de nivel correlacional.La población estuvo conformada por 141 internos de medicina humana de la Universidad Católica de Santa María. Como técnica se usó la encuesta y como instrumento el cuestionario. Se usó estadística descriptiva e inferencial a través de pruebas de hipótesis con un margen de error del 5% RESULTADOS: Los resultados han demostrado que más del 40% de internos de medicina, bajo el contexto covid-19 tuvieron un nivel regular y alto en las habilidades sociales de forma simultánea. El 58.9% tuvo un nivel regular en la dimensión situacional, el 52.5% tuvo un nivel regular en la dimensión social, el 57.4% tuvo un nivel regular en la dimensión conductual. Con respecto a la variable agresividad, el 43.3% de internos tuvieron un nivel regular de agresividad. CONCLUSIÓN: El resultado más predominante de asociación en la tabla cruzada fue del 22% de internos de medicina que tuvieron un nivel alto de habilidades sociales y un nivel regular de agresividad y el valor de significancia obtenido fue de 0.0295. Este resultado permite establecer que no existe una relación significativa e indirecta entre las habilidades sociales y la agresividad en internos de medicina de la Universidad Católica de Santa María de Arequipa, 2022

All-optical OFDM and distributed Raman amplification:challenges to enable high capacities and extend reach

We review recent advances in all-optical OFDM technologies and discuss the performance of a field trial of a 2 Tbit/s Coherent WDM over 124 km with distributed Raman amplification. The results indicate that careful optimisation of the Raman pumps is essential. We also consider how all-optical OFDM systems perform favourably against energy consumption when compared with alternative coherent detection schemes. We argue that, in an energy constrained high-capacity transmission system, direct detected all-optical OFDM with `ideal' Raman amplification is an attractive candidate for metro area datacentre interconnects with ~100 km fibre spans, with an overall energy requirement at least three times lower than coherent detection techniques

Late Holocene lake level dynamics inferred from magnetic susceptibility and stable oxygen isotope data: Lake Elsinore, southern California (USA)

Southern California faces an imminent freshwater shortage. To better assess the future impact of this water crisis, it is essential that we develop continental archives of past hydrological variability. Using four sediment cores from Lake Elsinore in Southern California, we reconstruct late Holocene (∼3800 calendar years B.P.) hydrological change using a twentieth-century calibrated, proxy methodology. We compared magnetic susceptibility from Lake Elsinore deep basin sediments, lake level from Lake Elsinore, and regional winter precipitation data over the twentieth century to calibrate the late Holocene lake sediment record. The comparison revealed a strong positive, first-order relationship between the three variables. As a working hypothesis, we suggest that periods of greater precipitation produce higher lake levels. Greater precipitation also increases the supply of detritus (i.e., magnetic-rich minerals) from the lake's surrounding drainage basin into the lake environment. As a result, magnetic susceptibility values increase during periods of high lake level. We apply this modern calibration to late Holocene sediments from the lake's littoral zone. As an independent verification of this hypothesis, we analyzed δ 18 O (calcite) , interpreted as a proxy for variations in the precipitation:evaporation ratio, which reflect first order hydrological variability. The results of this verification support our hypothesis that magnetic susceptibility records regional hydrological change as related to precipitation and lake level. Using both proxy data, we analyzed the past 3800 calendar years of hydrological variability. Our analyses indicate a long period of dry, less variable climate between 3800 and 2000 calendar years B.P. followed by a wet, more variable climate to the present. These results suggest that droughts of greater magnitude and duration than those observed in the modern record have occurred in the recent geological past. This conclusion presents insight to the potential impact of future droughts on the over-populated, water-poor region of Southern California.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/43089/1/10933_2004_Article_5147767.pd

1962

Turf on the Launching Pad (page 1) Turf management Club News (3) Education, Experience and Attitude (4) A Blade of Grass (5) Picture - Professor Lawrence S. Dickinson (6) Picture - Thomas Mascaro - Banquet Speaker (7) Planting Trees on the Golf Course (8) Two-Way Radios (8) Greens Mowing Procedure (9) Watering and Topdressing as Related to Poa annua Infestations (10) Picture - Stockbridge Majors in Turf Management (12) Picture - Graduates of Winter School for Turf Managers - 1962 (13) Review of Season\u27s Pests by Joseph Troll (A-1) Today\u27s Trends in Golf Course Development by Col. Harry C. Eckoff (A-3) Breeding and Selection of Fine Turf Grasses by Dr. B. R. Anderson Penncross Bentgrass by J. Dutch(A-13) Poa annua by Alexander Radko (A-16) Velvet Bent by Jesse DeFrance (A-19) Vegetative Creeping Bentgrasses by Fred Grau (A-21) Modification of SOils for Green Construction & Top Dressing by Prof. H. B. Musser (A-27) Soil COmpaction by Donald Waddington (A-32) Irrigation Practices and the Need of Basic Research by Prof. Edward PIra (A-36) Water Sources by Z. Mills (A-39) Athletic Field Maintenance by Thomas Mascaro (A-41) Planning the Landscape Around the House by Prof. Harold Mosher (A-43

Reviewing progress: 7 Year Trends in Characteristics of Adults and Children Enrolled at HIV Care and Treatment Clinics in the United Republic of Tanzania.

To evaluate the on-going scale-up of HIV programs, we assessed trends in patient characteristics at enrolment and ART initiation over 7 years of implementation. Data were from Optimal Models, a prospective open cohort study of HIV-infected (HIV+) adults (>=15 years) and children (<15 years) enrolled from January 2005 to December 2011 at 44 HIV clinics in 3 regions of mainland Tanzania (Kagera, Kigoma, Pwani) and Zanzibar. Comparative statistics for trends in characteristics of patients enrolled in 2005--2007, 2008--2009 and 2010--2011 were examined. Overall 62,801 HIV+ patients were enrolled: 58,102(92.5%) adults, (66.5% female); 4,699(7.5%) children.Among adults, pregnant women enrolment increased: 6.8%, 2005--2007; 12.1%, 2008--2009; 17.2%, 2010--2011; as did entry into care from prevention of mother-to-child HIV transmission (PMTCT) programs: 6.6%, 2005--2007; 9.5%, 2008--2009; 12.6%, 2010--2011. WHO stage IV at enrolment declined: 27.1%, 2005--2007; 20.2%, 2008--2009; 11.1% 2010--2011. Of the 42.5% and 29.5% with CD4+ data at enrolment and ART initiation respectively, median CD4+ count increased: 210cells/muL, 2005--2007; 262cells/muL, 2008--2009; 266cells/muL 2010--2011; but median CD4+ at ART initiation did not change (148cells/muL overall). Stavudine initiation declined: 84.9%, 2005--2007; 43.1%, 2008--2009; 19.7%, 2010--2011.Among children, median age (years) at enrolment decreased from 6.1(IQR:2.7-10.0) in 2005--2007 to 4.8(IQR:1.9-8.6) in 2008--2009, and 4.1(IQR:1.5-8.1) in 2010--2011 and children <24 months increased from 18.5% to 26.1% and 31.5% respectively. Entry from PMTCT was 7.0%, 2005--2007; 10.7%, 2008--2009; 15.0%, 2010--2011. WHO stage IV at enrolment declined from 22.9%, 2005--2007, to 18.3%, 2008--2009 to 13.9%, 2010--2011. Proportion initiating stavudine was 39.8% 2005--2007; 39.5%, 2008--2009; 26.1%, 2010--2011. Median age at ART initiation also declined significantly. Over time, the proportion of pregnant women and of adults and children enrolled from PMTCT programs increased. There was a decline in adults and children with advanced HIV disease at enrolment and initiation of stavudine. Pediatric age at enrolment and ART initiation declined. Results suggest HIV program maturation from an emergency response

Evasion of anti-growth signaling: a key step in tumorigenesis and potential target for treatment and prophylaxis by natural compounds

The evasion of anti-growth signaling is an important characteristic of cancer cells. In order to continue to proliferate, cancer cells must somehow uncouple themselves from the many signals that exist to slow down cell growth. Here, we define the anti-growth signaling process, and review several important pathways involved in growth signaling: p53, phosphatase and tensin homolog (PTEN), retinoblastoma protein (Rb), Hippo, growth differentiation factor 15 (GDF15), AT-rich interactive domain 1A (ARID1A), Notch, insulin-like growth factor (IGF), and Krüppel-like factor 5 (KLF5) pathways. Aberrations in these processes in cancer cells involve mutations and thus the suppression of genes that prevent growth, as well as mutation and activation of genes involved in driving cell growth. Using these pathways as examples, we prioritize molecular targets that might be leveraged to promote anti-growth signaling in cancer cells. Interestingly, naturally-occurring phytochemicals found in human diets (either singly or as mixtures) may promote anti-growth signaling, and do so without the potentially adverse effects associated with synthetic chemicals. We review examples of naturally-occurring phytochemicals that may be applied to prevent cancer by antagonizing growth signaling, and propose one phytochemical for each pathway. These are: epigallocatechin-3-gallate (EGCG) for the Rb pathway, luteolin for p53, curcumin for PTEN, porphyrins for Hippo, genistein for GDF15, resveratrol for ARID1A, withaferin A for Notch and diguelin for the IGF1-receptor pathway. The coordination of anti-growth signaling and natural compound studies will provide insight into the future application of these compounds in the clinical setting

Indicators of "Healthy Aging" in older women (65-69 years of age). A data-mining approach based on prediction of long-term survival

<p>Abstract</p> <p>Background</p> <p>Prediction of long-term survival in healthy adults requires recognition of features that serve as early indicators of successful aging. The aims of this study were to identify predictors of long-term survival in older women and to develop a multivariable model based upon longitudinal data from the Study of Osteoporotic Fractures (SOF).</p> <p>Methods</p> <p>We considered only the youngest subjects (<it>n </it>= 4,097) enrolled in the SOF cohort (65 to 69 years of age) and excluded older SOF subjects more likely to exhibit a "frail" phenotype. A total of 377 phenotypic measures were screened to determine which were of most value for prediction of long-term (19-year) survival. Prognostic capacity of individual predictors, and combinations of predictors, was evaluated using a cross-validation criterion with prediction accuracy assessed according to time-specific AUC statistics.</p> <p>Results</p> <p>Visual contrast sensitivity score was among the top 5 individual predictors relative to all 377 variables evaluated (mean AUC = 0.570). A 13-variable model with strong predictive performance was generated using a forward search strategy (mean AUC = 0.673). Variables within this model included a measure of physical function, smoking and diabetes status, self-reported health, contrast sensitivity, and functional status indices reflecting cumulative number of daily living impairments (HR ≥ 0.879 or RH ≤ 1.131; P < 0.001). We evaluated this model and show that it predicts long-term survival among subjects assigned differing causes of death (e.g., cancer, cardiovascular disease; P < 0.01). For an average follow-up time of 20 years, output from the model was associated with multiple outcomes among survivors, such as tests of cognitive function, geriatric depression, number of daily living impairments and grip strength (P < 0.03).</p> <p>Conclusions</p> <p>The multivariate model we developed characterizes a "healthy aging" phenotype based upon an integration of measures that together reflect multiple dimensions of an aging adult (65-69 years of age). Age-sensitive components of this model may be of value as biomarkers in human studies that evaluate anti-aging interventions. Our methodology could be applied to data from other longitudinal cohorts to generalize these findings, identify additional predictors of long-term survival, and to further develop the "healthy aging" concept.</p

CMS physics technical design report : Addendum on high density QCD with heavy ions

Peer reviewe