53 research outputs found
Oscillation of the tunnel splitting in nanospin systems within the particle mapping formalism
The oscillation of tunnel splitting in the biaxial spin system within
magnetic field along the anisotropy axis is analyzed within the particle
mapping approach, rather than in the (\theta-\phi) spin coherent-state
representation. In our mapping procedure, the spin system is transformed into a
particle moving in the restricted geometry whose wave function subjects
to the boundary condition involving additional phase shift. We obtain the new
topological phase that plays the same role as the Wess-Zumino action in spin
coherent-state representation. Considering the interference of two possible
trajectories, instanton and anti-instanton, we get the identical condition for
the field at which tunneling is quenched, with the previous result within spin
coherent-state representation.Comment: 11 pages, 1 figure; Some typographical errors have been correcte
Aspects of Puff Field Theory
We describe some features of the recently constructed "Puff Field Theory,"
and present arguments in favor of it being a field theory decoupled from
gravity. We construct its supergravity dual and calculate the entropy of this
theory in the limit of large 't Hooft coupling. We also determine the leading
irrelevant operator that governs its deviation from N=4 super Yang-Mills
theory.Comment: 31 pages, 1 figur
Genome-Wide Association Study in BRCA1 Mutation Carriers Identifies Novel Loci Associated with Breast and Ovarian Cancer Risk
BRCA1-associated breast and ovarian cancer risks can be modified by common genetic variants. To identify further cancer risk-modifying loci, we performed a multi-stage GWAS of 11,705 BRCA1 carriers (of whom 5,920 were diagnosed with breast and 1,839 were diagnosed with ovarian cancer), with a further replication in an additional sample of 2,646 BRCA1 carriers. We identified a novel breast cancer risk modifier locus at 1q32 for BRCA1 carriers (rs2290854, P = 2.7×10-8, HR = 1.14, 95% CI: 1.09-1.20). In addition, we identified two novel ovarian cancer risk modifier loci: 17q21.31 (rs17631303, P = 1.4×10-8, HR = 1.27, 95% CI: 1.17-1.38) and 4q32.3 (rs4691139, P = 3.4×10-8, HR = 1.20, 95% CI: 1.17-1.38). The 4q32.3 locus was not associated with ovarian cancer risk in the general population or BRCA2 carriers, suggesting a BRCA1-specific associat
Large expert-curated database for benchmarking document similarity detection in biomedical literature search
Document recommendation systems for locating relevant literature have mostly relied on methods developed a decade ago. This is largely due to the lack of a large offline gold-standard benchmark of relevant documents that cover a variety of research fields such that newly developed literature search techniques can be compared, improved and translated into practice. To overcome this bottleneck, we have established the RElevant LIterature SearcH consortium consisting of more than 1500 scientists from 84 countries, who have collectively annotated the relevance of over 180 000 PubMed-listed articles with regard to their respective seed (input) article/s. The majority of annotations were contributed by highly experienced, original authors of the seed articles. The collected data cover 76% of all unique PubMed Medical Subject Headings descriptors. No systematic biases were observed across different experience levels, research fields or time spent on annotations. More importantly, annotations of the same document pairs contributed by different scientists were highly concordant. We further show that the three representative baseline methods used to generate recommended articles for evaluation (Okapi Best Matching 25, Term Frequency-Inverse Document Frequency and PubMed Related Articles) had similar overall performances. Additionally, we found that these methods each tend to produce distinct collections of recommended articles, suggesting that a hybrid method may be required to completely capture all relevant articles. The established database server located at https://relishdb.ict.griffith.edu.au is freely available for the downloading of annotation data and the blind testing of new methods. We expect that this benchmark will be useful for stimulating the development of new powerful techniques for title and title/abstract-based search engines for relevant articles in biomedical research.Peer reviewe
Two-dimensional echocardiographic detection of biventricular thrombi.
Singapore Medical Journal361110-11
Aortic root cardioplegia: An adequate method for myocardial protection in complete occlusion of the left main coronary artery
The Asia Pacific Journal of Thoracic and Cardiovascular Surgery3136-3
Overestimation of severity of mitral stenosis during cardiac catheterization due to a large left atrial thrombus.
Singapore Medical Journal335530-53
Intravascular hemolysis after mitral valve repair: a word of caution
European Journal of Cardio-Thoracic Surgery62103-104,105EJCS
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