The Sunyaev-Zel'dovich temperature of the intracluster medium

The relativistic Sunyaev-Zel'dovich (SZ) effect offers a method, independent of X-ray, for measuring the temperature of the intracluster medium (ICM) in the hottest systems. Here, using N-body/hydrodynamic simulations of three galaxy clusters, we compare the two quantities for a non-radiative ICM, and for one that is subject both to radiative cooling and strong energy feedback from galaxies. Our study has yielded two interesting results. Firstly, in all cases, the SZ temperature is hotter than the X-ray temperature and is within ten per cent of the virial temperature of the cluster. Secondly, the mean SZ temperature is less affected by cooling and feedback than the X-ray temperature. Both these results can be explained by the SZ temperature being less sensitive to the distribution of cool gas associated with cluster substructure. A comparison of the SZ and X-ray temperatures (measured for a sample of hot clusters) would therefore yield interesting constraints on the thermodynamic structure of the intracluster gas.Comment: This version accepted for publication in MNRAS following minor revisio

Outskirts of Galaxy Clusters

Until recently, only about 10% of the total intracluster gas volume had been studied with high accuracy, leaving a vast region essentially unexplored. This is now changing and a wide area of hot gas physics and chemistry awaits discovery in galaxy cluster outskirts. Also, robust large-scale total mass profiles and maps are within reach. First observational and theoretical results in this emerging field have been achieved in recent years with sometimes surprising findings. Here, we summarize and illustrate the relevant underlying physical and chemical processes and review the recent progress in X-ray, Sunyaev--Zel'dovich, and weak gravitational lensing observations of cluster outskirts, including also brief discussions of technical challenges and possible future improvements.Comment: 52 pages. Review paper. Accepted for publication in Space Science Reviews (eds: S. Ettori, M. Meneghetti). This is a product of the work done by an international team at the International Space Science Institute (ISSI) in Bern on "Astrophysics and Cosmology with Galaxy Clusters: the X-ray and Lensing View

CARMA Measurements of the Sunyaev-Zel'dovich Effect in RXJ1347.5-1145

We demonstrate the Sunyaev-Zel'dovich (SZ) effect imaging capabilities of the Combined Array for Research in Millimeter-wave Astronomy (CARMA) by presenting an SZ map of the galaxy cluster RXJ1347.5-1145. By combining data from multiple CARMA bands and configurations, we are able to capture the structure of this cluster over a wide range of angular scales, from its bulk properties to its core morphology. We find that roughly 9% of this cluster's thermal energy is associated with sub-arcminute-scale structure imparted by a merger, illustrating the value of high-resolution SZ measurements for pursuing cluster astrophysics and for understanding the scatter in SZ scaling relations. We also find that the cluster's SZ signal is lower in amplitude than suggested by a spherically-symmetric model derived from X-ray data, consistent with compression along the line of sight relative to the plane of the sky. Finally, we discuss the impact of upgrades currently in progress that will further enhance CARMA's power as an SZ imaging instrument.Comment: 8 pages, 6 figure

The central dark matter content of early-type galaxies: scaling relations and connections with star formation histories

We examine correlations between the masses, sizes, and star formation histories for a large sample of low-redshift early-type galaxies, using a simple suite of dynamical and stellar populations models. We confirm an anti-correlation between size and stellar age, and survey for trends with the central content of dark matter (DM). An average relation between central DM density and galaxy size of ~ Reff^-2 provides the first clear indication of cuspy DM haloes in these galaxies -- akin to standard LCDM haloes that have undergone adiabatic contraction. The DM density scales with galaxy mass as expected, deviating from suggestions of a universal halo profile for dwarf and late-type galaxies. We introduce a new fundamental constraint on galaxy formation by finding that the central DM fraction decreases with stellar age. This result is only partially explained by the size-age dependencies, and the residual trend is in the opposite direction to basic DM halo expectations. Therefore we suggest that there may be a connection between age and halo contraction, and that galaxies forming earlier had stronger baryonic feedback which expanded their haloes, or else lumpier baryonic accretion that avoided halo contraction. An alternative explanation is a lighter initial mass function for older stellar populations.Comment: 24 pages, 23 figures. MNRAS, submitted with minor modifications following referee report

Parameterization Effects in the analysis of AMI Sunyaev-Zel'dovich Observations

Most Sunyaev--Zel'dovich (SZ) and X-ray analyses of galaxy clusters try to constrain the cluster total mass and/or gas mass using parameterised models and assumptions of spherical symmetry and hydrostatic equilibrium. By numerically exploring the probability distributions of the cluster parameters given the simulated interferometric SZ data in the context of Bayesian methods, and assuming a beta-model for the electron number density we investigate the capability of this model and analysis to return the simulated cluster input quantities via three rameterisations. In parameterisation I we assume that the T is an input parameter. We find that parameterisation I can hardly constrain the cluster parameters. We then investigate parameterisations II and III in which fg(r200) replaces temperature as a main variable. In parameterisation II we relate M_T(r200) and T assuming hydrostatic equilibrium. We find that parameterisation II can constrain the cluster physical parameters but the temperature estimate is biased low. In parameterisation III, the virial theorem replaces the hydrostatic equilibrium assumption. We find that parameterisation III results in unbiased estimates of the cluster properties. We generate a second simulated cluster using a generalised NFW (GNFW) pressure profile and analyse it with an entropy based model to take into account the temperature gradient in our analysis and improve the cluster gas density distribution. This model also constrains the cluster physical parameters and the results show a radial decline in the gas temperature as expected. The mean cluster total mass estimates are also within 1 sigma from the simulated cluster true values. However, we find that for at least interferometric SZ analysis in practice at the present time, there is no differences in the AMI visibilities between the two models. This may of course change as the instruments improve.Comment: 19 pages, 13 tables, 24 figure

The impact of dust on the scaling properties of galaxy clusters

We investigate the effect of dust on the scaling properties of galaxy clusters based on hydrodynamic N-body simulations of structure formation. We have simulated five dust models plus a radiative cooling and adiabatic models using the same initial conditions for all runs. The numerical implementation of dust was based on the analytical computations of Montier and Giard (2004). We set up dust simulations to cover different combinations of dust parameters that put in evidence the effects of size and abundance of dust grains. Comparing our radiative plus dust cooling runs to a purely radiative cooling simulation we find that dust has an impact on cluster scaling relations. It mainly affects the normalisation of the scalings (and their evolution), whereas it introduces no significant differences on their slopes. The strength of the effect depends critically on the dust abundance and grain size parameters as well as on the cluster scaling. Indeed, cooling due to dust is effective at the cluster regime and has a stronger effect on the "baryon driven" statistical properties of clusters such as $L_{\rm X}-M$, $Y- M$, $S-M$ scaling relations. Major differences, relative to the radiative cooling model, are as high as 25% for the $L_{\rm X}-M$ normalisation, and about 10% for the $Y-M$ and $S-M$ normalisations at redshift zero. On the other hand, we find that dust has almost no impact on the "dark matter driven" $T_{\rm mw}-M$ scaling relation. The effects are found to be dependent in equal parts on both dust abundances and grain sizes distributions for the scalings investigated in this paper. Higher dust abundances and smaller grain sizes cause larger departures from the radiative cooling (i.e. with no dust) model.Comment: 12 pages, 6 figures, submitted to MNRA

Radial structure, inflow and central mass of stationary radiative galaxy clusters

We analyse the radial structure of self-gravitating spheres consisting of multiple interpenetrating fluids, such as the X-ray emitting gas and the dark halo of a galaxy cluster. In these dipolytropic models, the adiabatic dark matter sits in equilibrium, while the gas develops a gradual, smooth, quasi-stationary cooling flow. Both affect and respond to the collective gravitational field. We find that all subsonic, radially continuous, steady solutions require a non-zero minimum central point mass. For Mpc-sized haloes with 7–10 effective degrees of freedom (F2), the minimum central mass is compatible with observations of supermassive black holes. Smaller gas mass influxes enable smaller central masses for wider ranges of F2. The halo comprises a sharp spike around the central mass, embedded within a core of nearly constant density (at 101–102.5 kpc scales), with outskirts that attenuate and naturally truncate at finite radius (several Mpc). The gas density resembles a broken power law in radius, but the temperature dips and peaks within the dark core. A finite minimum temperature occurs due to gravitational self-warming, without cold mass dropout nor needing regulatory heating. X-ray emission from the intracluster medium mimics a β-model plus bright compact nucleus. Near-sonic points in the gas flow are bottlenecks to the allowed steady solutions; the outermost are at kpc scales. These sites may preferentially develop cold mass dropout during strong perturbations off equilibrium. Within the sonic point, the profile of gas specific entropy is flatter than s∝r1/2, but this is a shallow ramp and not an isentropic core. When F2 is large, the inner halo spike is only marginally Jeans stable in the central parsec, suggesting that a large non-linear disturbance could trigger local dark collapse on to the central object

The Double Galaxy Cluster Abell 2465 I. Basic Properties: Optical Imaging and Spectroscopy

Optical imaging and spectroscopic observations of the z = 0.245 double galaxy cluster Abell 2465 are described. This object appears to be undergoing a major merger. It is a double X-ray source and is detected in the radio at 1.4 GHz. This paper investigates signatures of the interaction of the two components. Redshifts were measured to determine velocity dispersions and virial radii of each component. The technique of fuzzy clustering was used to assign membership weights to the galaxies in each clump. Using redshifts of 93 cluster members within 1.4 Mpc of the subcluster centres, the virial masses and anisotropy parameters are derived. 37% of the spectroscopically observed galaxies show emission lines and are predominantly star forming in the diagnostic diagram. No strong AGN sources were found. The emission line galaxies tend to lie between the two cluster centres with more near the SW clump. The luminosity functions of the two subclusters differ. The NE component is similar to many rich clusters, while the SW component has more faint galaxies. The NE clump's light profile follows a single NFW profile with c = 10 while the SW is better fit with an extended outer region and a compact inner core, consistent with available X-ray data indicating that the SW clump has a cooling core. The observed differences and properties of the two components of Abell 2465 are interpreted to have been caused by a collision 2-4 Gyr ago, after which they have moved apart and are now near their apocentres, although the start of a merger remains a possibility. The number of emission line galaxies gives weight to the idea that galaxy cluster collisions trigger star formation.Comment: 21 pages, 18 Figures Replaced typos, mostly in references To appear in MNRAS, Accepted 2010 December 16. Received 2010 December 15; in original form 2010 November 0

Inhibition of Chondrosarcoma Growth by mTOR Inhibitor in an In Vivo Syngeneic Rat Model

BACKGROUND: Chondrosarcomas are the second most frequent primary malignant type of bone tumor. No effective systemic treatment has been identified in advanced or adjuvant phases for chondrosarcoma. The aim of the present study was to determine the antitumor effects of doxorubicin and everolimus, an mTOR inhibitor on chondrosarcoma progression. METHODS AND FINDINGS: Doxorubin and/or everolimus were tested in vivo as single agent or in combination in the rat orthotopic Schwarm chondrosarcoma model, in macroscopic phase, as well as with microscopic residual disease. Response to everolimus and/or doxorubicin was evaluated using chondrosarcoma volume evolution (MRI). Histological response was evaluated with % of tumor necrosis, tumor proliferation index, metabolism quantification analysis between the treated and control groups. Statistical analyses were performed using chi square, Fishers exact test. Doxorubicin single agent has no effect of tumor growth as compared to no treatment; conversely, everolimus single agent significantly inhibited tumor progression in macroscopic tumors with no synergistic additive effect with doxorubicin. Everolimus inhibited chondrosarcoma proliferation as evaluated by Ki67 expression did not induce the apoptosis of tumor cells; everolimus reduced Glut1 and 4EBP1 expression. Importantly when given in rats with microscopic residual diseases, in a pseudo neoadjuvant setting, following R1 resection of the implanted tumor, everolimus significantly delayed or prevented tumor recurrence. CONCLUSIONS: MTOR inhibitor everolimus blocks cell proliferation, Glut1 expression and HIF1a expression, and prevents in vivo chondrosarcoma tumor progression in both macroscopic and in adjuvant phase post R1 resection. Taken together, our preclinical data indicate that mTOR inhibitor may be effective as a single agent in treating chondrosarcoma patients. A clinical trial evaluating mTOr inhibitor as neo-adjuvant and adjuvant therapy in chondrosarcoma patients is being constructed