2,015 research outputs found
Galaxy groups in the 2dF redshift survey: The catalogue
We construct a galaxy groups catalogue from the public 100K data release of
the 2dF galaxy redshift survey. The group identification is carried out using a
slightly modified version of the group finding algorithm developed by Huchra &
Geller. Several tests using mock catalogues allow us to find the optimal
conditions to increase the reliability of the final group sample. A minimum
number of 4 members, an outer number density enhancement of 80 and a linking
radial cutoff of , are the best obtained values from the
analysis. Using these parameters, approximately 90% of groups identified in
real space have a redshift space counterpart. On the other hand the level of
contamination in redshift space reaches to 30 % including a of
artificial groups and of groups associated with binaries or triplets
in real space. The final sample comprise 2209 galaxy groups covering the sky
region described by Colless et al. spanning over the redshift range of with a mean redshift of 0.1.Comment: Accepted for publication in the MNRAS. 8 figures 8 page
Photo-damage, photo-protection and age-related macular degeneration
Age-related macular degeneration (AMD) is a degenerative retinal disease that causes blindness in people 60-65 years and older, with the highest prevalence appearing in people 90 years-old or more. Epidemiological estimates indicate that the number of cases is increasing, and will almost double in the next 20 years. Preventive measures require precise etiological knowledge. This is quite difficult, since AMD is a multifactorial condition with intricate relationships between causes and risk factors. In this review, we describe the impact of light on the structure and physiology of the retina and the pigment epithelium, taking into account the continuous exposure to natural and artificial light sources along the life of an individual. A large body of experimental evidence demonstrates the toxic effects of some lighting conditions on the retina and the pigment epithelium, and consensus exists about the importance of photo-oxidation phenomena in the causality chain between light and retinal damage. Here, we analyzed the transmission of light to the retina, and compared the aging human macula in healthy and diseased retinas, as shown by histology and non-invasive imaging systems. Finally, we have compared the putative retinal photo-sensitive molecular structures that might be involved in the genesis of AMD. The relationship between these compounds and retinal damage supports the hypothesis of light as an important initiating cause of AMD.Fil: Marquioni Ramella, Melisa Daniela. Universidad Austral. Facultad de Ciencias Biomédicas. Laboratorio de Investigaciones Biomédicas; Argentina. Consejo Nacional de Investigaciones CientÃficas y Técnicas; ArgentinaFil: Suburo, Angela Maria. Consejo Nacional de Investigaciones CientÃficas y Técnicas; Argentina. Universidad Austral. Facultad de Ciencias Biomédicas. Laboratorio de Investigaciones Biomédicas; Argentin
"Imeneo sotto il platano": un motivo bucolico in Claudiano (carm. min. 25)
Nelle scene del sonno di Venere e del dialogo tra Venere e Imeneo, l’Epitalamio
per Palladio e Celerina di Claudiano (carm. min. 25) si distingue dalla tradizione
epitalamica per l'atmosfera bucolica, evocata da una serie di riferimenti tematici
e formali al genere letterario. Le parole di Venere e Imeneo sembrano comunicare
un articolata riflessione dell'autore sulla poetica espressa nell'epitalamio: Imeneo
fungerebbe da portavoce di Claudiano, rivendicando la possibilità per il poeta di
adattare i toni bucolici alle esigenze encomiastiche del carme d occasione. È possibile
che lo sviluppo narrativo dell'episodio di Imeneo sia stato suggerito a Claudiano
dall'inno cletico del carme 61 di Catullo. Claudiano potrebbe aver sfruttato le
possibilità offerte dalla forma dell'epitalamio epico per fare dell'invocazione a Imeneo
un episodio organico al racconto.In the scenes of Venus’ sleep and of the dialogue between Venus and Hymenaeus, Claudian's
Epithalamium for Palladius and Celerina (carm. min. 25) stands out from the
epithalamic tradition for its bucolic atmosphere, which is summoned by several thematic
and stylistic references to the literary genre. The words of Venus and Hymenaeus seem to
communicate an articulate reflection of the author on the poetics of the epithalamium:
Hymenaeus may be acting as spokesman for Claudian, claiming the possibility for the poet
to adapt the bucolic modes to the encomiastic needs of the occasional poem. The narrative
development of Hymenaeus’ episode might have been suggested to Claudian by the cletic
hymn of Catullus 61. Claudian seems to have taken advantage of the possibilities offered
by the form of the epic epithalamium in order to make the invocation to Hymenaeus an
episode incorporated in the narrative
Untied to economic fluctuations, insurers are less likely to generate systemic risks
But it's important not to overlook nuances in their macroprudential regulation, writes Marcelo Ramell
Endothelial MMP-9 Drives the Inflammatory Response in Abdominal Aortic Aneurysm (AAA)
Abdominal aortic aneurysm (AAA) is a complex multi-factorial disease leading to life-threatening complications. Chronic inflammation and extracellular matrix degradation are the major pathological features of AAA. Vascular inflammation involves complex interaction among inflammatory cells (i.e. neutrophils, lymphocytes, monocytes, macrophages), endothelial cells (ECs), vascular smooth muscle cells (VSMCs), and extracellular matrix (ECM). Although vascular endothelium plays a key role in aneurysm disease, the molecular mechanisms underlying its involvement is only partially understood. In this study, we have characterized the role of matrix matrix metalloproteinase-9 (MMP-9) as potential trigger of the inflammatory response during the reciprocal interaction between ECs and VSMCs. Briefly, in biopsies of human AAA we found increased level of MMP-9, IL-6 and monocyte chemoattractant protein-1 (MCP-1), which correlated with a massive medial neo-angiogenesis. In particular, in vitro silencing of MMP-9 in ECs, using specific shRNA delivered by lentiviral vectors, inhibited TNF-alpha mediated activation of NF-kB. In addition, ECS void of MMP-9 failed to migrate in 3D matrix and affected VSMC behavior in terms of matrix remodeling. Overall our findings indicate that silencing of MMP-9 may represent a therapeutic target to restore vascular extracellular matrix remodeling
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