Ethos im Lehrberuf

Dieses Manual soll es angehenden Lehrer*innen in der ersten Phase der Lehrkräfteausbildung ermöglichen, mit dem Thema ‚Ethos‘ in Kontakt zu treten und es als ein wichtiges Feld der professionellen Entwicklung kennen zu lernen. Das Manual ist für den Einsatz in der Lehrer*innenbildung an Hochschulen konzipiert und richtet sich vornehmlich an Dozierende in diesen Lehrbereichen. Darüber hinaus kann es aber auch von Lehrer*innen in der zweiten und dritten Phase für Fort- und Weiterbildung genutzt werden. Dazu finden sich im Manual einführende Texte zu den Themen Ethos (Kapitel 1), zur professionstheoretischen Verortung des pädagogischen Ethos in einem Domänenmodell der Professionalität (EPIK-Domänen, Kapitel 2) und zur praktischen Anwendung des Manuals in der Hochschullehre (Kapitel 3). Neben diesen einführenden Kapiteln besteht das ‚Herzstück‘ des Manuals in einer Sammlung von 24 Beispielen aus der schulischen Praxis (Kapitel 4). Sie alle stammen aus den Praktikumsreflexionen angehender Lehrer*innen, sie alle beschreiben herausfordernde Situationen, in denen Ethos gefragt ist oder sich zeigt – wir nennen dies eine Situation, die sich durch ethische Ambiguität auszeichnet. So führen die Beispiele ein in eine Praxis der Stellungnahme und des Fällens von (ethischen) Urteilen, eine Form der Übung, die zur Herausbildung eines Ethos beiträgt.This manual is intended to enable prospective teachers in the first phase of teacher education to get in touch with the topic of 'ethos' and to get to know it as an important field of professional development. The manual is designed for use in teacher education at universities and is primarily aimed at lecturers in these teaching areas. However, it can also be used by teachers in the second and third phase for further education and training. For this purpose, the manual contains introductory texts on the topics of ethos (chapter 1), on the professional-theoretical location of the pedagogical ethos in a domain model of professionalism (EPIK domains, chapter 2), and on the practical application of the manual in university teaching (chapter 3). In addition to these introductory chapters, the 'heart' of the manual is a collection of 24 examples from school-based practice (Chapter 4). They all come from the internship reflections of prospective teachers, they all describe challenging situations in which ethos is required or manifests itself - we call this a situation characterized by ethical ambiguity. Thus, the examples introduce a practice of taking a stand and making (ethical) judgments, a form of exercise that contributes to the formation of an ethos.Not Reviewe

Search for dark matter produced in association with bottom or top quarks in √s = 13 TeV pp collisions with the ATLAS detector

A search for weakly interacting massive particle dark matter produced in association with bottom or top quarks is presented. Final states containing third-generation quarks and miss- ing transverse momentum are considered. The analysis uses 36.1 fb−1 of proton–proton collision data recorded by the ATLAS experiment at √s = 13 TeV in 2015 and 2016. No significant excess of events above the estimated backgrounds is observed. The results are in- terpreted in the framework of simplified models of spin-0 dark-matter mediators. For colour- neutral spin-0 mediators produced in association with top quarks and decaying into a pair of dark-matter particles, mediator masses below 50 GeV are excluded assuming a dark-matter candidate mass of 1 GeV and unitary couplings. For scalar and pseudoscalar mediators produced in association with bottom quarks, the search sets limits on the production cross- section of 300 times the predicted rate for mediators with masses between 10 and 50 GeV and assuming a dark-matter mass of 1 GeV and unitary coupling. Constraints on colour- charged scalar simplified models are also presented. Assuming a dark-matter particle mass of 35 GeV, mediator particles with mass below 1.1 TeV are excluded for couplings yielding a dark-matter relic density consistent with measurements

Genome-wide Association Study Identifies Genetic Variation in Neurocan as a Susceptibility Factor for Bipolar Disorder

We conducted a genome-wide association study (GWAS) and a follow-up study of bipolar disorder (BD), a common neuropsychiatric disorder. In the GWAS, we investigated 499,494 autosomal and 12,484 X-chromosomal SNPs in 682 patients with BD and in 1300 controls. In the first follow-up step, we tested the most significant 48 SNPs in 1729 patients with BD and in 2313 controls. Eight SNPs showed nominally significant association with BD and were introduced to a meta-analysis of the GWAS and the first follow-up samples. Genetic variation in the neurocan gene (NCAN) showed genome-wide significant association with BD in 2411 patients and 3613 controls (rs1064395, p = 3.02 × 10(-8); odds ratio = 1.31). In a second follow-up step, we replicated this finding in independent samples of BD, totaling 6030 patients and 31,749 controls (p = 2.74 × 10(-4); odds ratio = 1.12). The combined analysis of all study samples yielded a p value of 2.14 × 10(-9) (odds ratio = 1.17). Our results provide evidence that rs1064395 is a common risk factor for BD. NCAN encodes neurocan, an extracellular matrix glycoprotein, which is thought to be involved in cell adhesion and migration. We found that expression in mice is localized within cortical and hippocampal areas. These areas are involved in cognition and emotion regulation and have previously been implicated in BD by neuropsychological, neuroimaging, and postmortem studies

Genetic influences on schizophrenia and subcortical brain volumes:Large-scale proof of concept

Schizophrenia is a devastating psychiatric illness with high heritability. Brain structure and function differ, on average, between people with schizophrenia and healthy individuals. As common genetic associations are emerging for both schizophrenia and brain imaging phenotypes, we can now use genome-wide data to investigate genetic overlap. Here we integrated results from common variant studies of schizophrenia (33,636 cases, 43,008 controls) and volumes of several (mainly subcortical) brain structures (11,840 subjects). We did not find evidence of genetic overlap between schizophrenia risk and subcortical volume measures either at the level of common variant genetic architecture or for single genetic markers. These results provide a proof of concept (albeit based on a limited set of structural brain measures) and define a roadmap for future studies investigating the genetic covariance between structural or functional brain phenotypes and risk for psychiatric disorders

Measurements of ttˉt\bar{t} differential cross-sections of highly boosted top quarks decaying to all-hadronic final states in pppp collisions at s=13 \sqrt{s}=13\, TeV using the ATLAS detector

Measurements are made of differential cross-sections of highly boosted pair-produced top quarks as a function of top-quark and $t\bar{t}$ system kinematic observables using proton--proton collisions at a center-of-mass energy of $\sqrt{s} = 13$ TeV. The data set corresponds to an integrated luminosity of $36.1$ fb$^{-1}$, recorded in 2015 and 2016 with the ATLAS detector at the CERN Large Hadron Collider. Events with two large-radius jets in the final state, one with transverse momentum $p_{\rm T} > 500$ GeV and a second with $p_{\rm T}>350$ GeV, are used for the measurement. The top-quark candidates are separated from the multijet background using jet substructure information and association with a $b$-tagged jet. The measured spectra are corrected for detector effects to a particle-level fiducial phase space and a parton-level limited phase space, and are compared to several Monte Carlo simulations by means of calculated $\chi^2$ values. The cross-section for $t\bar{t}$ production in the fiducial phase-space region is $292 \pm 7 \ \rm{(stat)} \pm 76 \rm{(syst)}$ fb, to be compared to the theoretical prediction of $384 \pm 36$ fb

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

non present