Strategi Perancangan Komunikasi Visual Promosi Karya Seni Ukir Kayu Motif Khas Timor

ABSTRAK             Seni ukir kayu motif khas Timor merupakan salah satu produk  budaya asli Timor yang patut dilestarikan. Modernisasi menggerus hampir semua nilai dan aspek kehidupan, sehingga wawasan ketertarikan intens terhadap seni ukir dengan motif khas Timor sangatlah terbatas. Penelitian ini bertujuan untuk  1) Mengidentifikasi kekuatan, kelemahan, peluang, dan ancaman pelestarian seni ukir kayu motif khas Timor di Kecamatan Oebobo Kota Kupang dan 2) menyusun strategi perancangan komunikasi visual guna mendorong promosi seni ukir kayu motif khas Timor. Analisis data dilakukan dengan menggunakan SWOT.        Penelitian ini menghasilkan beberapa strategi perancangan yakni: a) kebutuhan pembinaan berkelanjutan peningkatan kualitas karya seni dan pemanfaatan media komunikasi visual untuk mempromosikan hasil karya dari para seniman ukir, b) membangun kerja sama pihak perguruan tinggi dan lembaga adat yang memiliki kepedulian terhadap kebudayaan Timor, c) perlu ada komunitas formal seniman ukir, serta  menjalin kerja sama untuk mengagendakan promosi hasil karya seni dalam berbagai event resmi pemerintah, d) perlu melibatkan lembaga /organisasi pemberdayaan terhadap hasil karya seni, sekaligus memberikan reward kepada generasi muda produktif yang menghasilkan karya seni berkualitas tinggi, dan e) adanya  media penyampaian informasi komunikasi visual berbasis online, sebagai sarana informasi hasil karya seni. Bahkan dapat dibangun gedung pusat promosi hasil karya seni

Search for direct production of charginos and neutralinos in events with three leptons and missing transverse momentum in √s = 7 TeV pp collisions with the ATLAS detector

A search for the direct production of charginos and neutralinos in final states with three electrons or muons and missing transverse momentum is presented. The analysis is based on 4.7 fb−1 of proton–proton collision data delivered by the Large Hadron Collider and recorded with the ATLAS detector. Observations are consistent with Standard Model expectations in three signal regions that are either depleted or enriched in Z-boson decays. Upper limits at 95% confidence level are set in R-parity conserving phenomenological minimal supersymmetric models and in simplified models, significantly extending previous results

Jet size dependence of single jet suppression in lead-lead collisions at sqrt(s(NN)) = 2.76 TeV with the ATLAS detector at the LHC

Measurements of inclusive jet suppression in heavy ion collisions at the LHC provide direct sensitivity to the physics of jet quenching. In a sample of lead-lead collisions at sqrt(s) = 2.76 TeV corresponding to an integrated luminosity of approximately 7 inverse microbarns, ATLAS has measured jets with a calorimeter over the pseudorapidity interval |eta| < 2.1 and over the transverse momentum range 38 < pT < 210 GeV. Jets were reconstructed using the anti-kt algorithm with values for the distance parameter that determines the nominal jet radius of R = 0.2, 0.3, 0.4 and 0.5. The centrality dependence of the jet yield is characterized by the jet "central-to-peripheral ratio," Rcp. Jet production is found to be suppressed by approximately a factor of two in the 10% most central collisions relative to peripheral collisions. Rcp varies smoothly with centrality as characterized by the number of participating nucleons. The observed suppression is only weakly dependent on jet radius and transverse momentum. These results provide the first direct measurement of inclusive jet suppression in heavy ion collisions and complement previous measurements of dijet transverse energy imbalance at the LHC.Comment: 15 pages plus author list (30 pages total), 8 figures, 2 tables, submitted to Physics Letters B. All figures including auxiliary figures are available at http://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/HION-2011-02

Novel genetic loci associated with hippocampal volume

The hippocampal formation is a brain structure integrally involved in episodic memory, spatial navigation, cognition and stress responsiveness. Structural abnormalities in hippocampal volume and shape are found in several common neuropsychiatric disorders. To identify the genetic underpinnings of hippocampal structure here we perform a genome-wide association study (GWAS) of 33,536 individuals and discover six independent loci significantly associated with hippocampal volume, four of them novel. Of the novel loci, three lie within genes (ASTN2, DPP4 and MAST4) and one is found 200 kb upstream of SHH. A hippocampal subfield analysis shows that a locus within the MSRB3 gene shows evidence of a localized effect along the dentate gyrus, subiculum, CA1 and fissure. Further, we show that genetic variants associated with decreased hippocampal volume are also associated with increased risk for Alzheimer's disease (rg =-0.155). Our findings suggest novel biological pathways through which human genetic variation influences hippocampal volume and risk for neuropsychiatric illness

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

Heart failure (HF) is a leading cause of morbidity and mortality worldwide. A small proportion of HF cases are attributable to monogenic cardiomyopathies and existing genome-wide association studies (GWAS) have yielded only limited insights, leaving the observed heritability of HF largely unexplained. We report results from a GWAS meta-analysis of HF comprising 47,309 cases and 930,014 controls. Twelve independent variants at 11 genomic loci are associated with HF, all of which demonstrate one or more associations with coronary artery disease (CAD), atrial fibrillation, or reduced left ventricular function, suggesting shared genetic aetiology. Functional analysis of non-CAD-associated loci implicate genes involved in cardiac development (MYOZ1, SYNPO2L), protein homoeostasis (BAG3), and cellular senescence (CDKN1A). Mendelian randomisation analysis supports causal roles for several HF risk factors, and demonstrates CAD-independent effects for atrial fibrillation, body mass index, and hypertension. These findings extend our knowledge of the pathways underlying HF and may inform new therapeutic strategies

Operation and performance of the ATLAS semiconductor tracker

The semiconductor tracker is a silicon microstrip detector forming part of the inner tracking system of the ATLAS experiment at the LHC. The operation and performance of the semiconductor tracker during the first years of LHC running are described. More than 99% of the detector modules were operational during this period, with an average intrinsic hit efficiency of (99.74±0.04)%. The evolution of the noise occupancy is discussed, and measurements of the Lorentz angle, δ-ray production and energy loss presented. The alignment of the detector is found to be stable at the few-micron level over long periods of time. Radiation damage measurements, which include the evolution of detector leakage currents, are found to be consistent with predictions and are used in the verification of radiation background simulations

Comparison between simulated and observed LHC beam backgrounds in the ATLAS experiment at Ebeam =4 TeV

Results of dedicated Monte Carlo simulations of beam-induced background (BIB) in the ATLAS experiment at the Large Hadron Collider (LHC) are presented and compared with data recorded in 2012. During normal physics operation this background arises mainly from scattering of the 4 TeV protons on residual gas in the beam pipe. Methods of reconstructing the BIB signals in the ATLAS detector, developed and implemented in the simulation chain based on the \textscFluka Monte Carlo simulation package, are described. The interaction rates are determined from the residual gas pressure distribution in the LHC ring in order to set an absolute scale on the predicted rates of BIB so that they can be compared quantitatively with data. Through these comparisons the origins of the BIB leading to different observables in the ATLAS detectors are analysed. The level of agreement between simulation results and BIB measurements by ATLAS in 2012 demonstrates that a good understanding of the origin of BIB has been reached

25th annual computational neuroscience meeting: CNS-2016

The same neuron may play different functional roles in the neural circuits to which it belongs. For example, neurons in the Tritonia pedal ganglia may participate in variable phases of the swim motor rhythms [1]. While such neuronal functional variability is likely to play a major role the delivery of the functionality of neural systems, it is difficult to study it in most nervous systems. We work on the pyloric rhythm network of the crustacean stomatogastric ganglion (STG) [2]. Typically network models of the STG treat neurons of the same functional type as a single model neuron (e.g. PD neurons), assuming the same conductance parameters for these neurons and implying their synchronous firing [3, 4]. However, simultaneous recording of PD neurons shows differences between the timings of spikes of these neurons. This may indicate functional variability of these neurons. Here we modelled separately the two PD neurons of the STG in a multi-neuron model of the pyloric network. Our neuron models comply with known correlations between conductance parameters of ionic currents. Our results reproduce the experimental finding of increasing spike time distance between spikes originating from the two model PD neurons during their synchronised burst phase. The PD neuron with the larger calcium conductance generates its spikes before the other PD neuron. Larger potassium conductance values in the follower neuron imply longer delays between spikes, see Fig. 17.Neuromodulators change the conductance parameters of neurons and maintain the ratios of these parameters [5]. Our results show that such changes may shift the individual contribution of two PD neurons to the PD-phase of the pyloric rhythm altering their functionality within this rhythm. Our work paves the way towards an accessible experimental and computational framework for the analysis of the mechanisms and impact of functional variability of neurons within the neural circuits to which they belong

4D objects-by-change: Spatiotemporal segmentation of geomorphic surface change from LiDAR time series

Time series of topographic data are becoming increasingly widespread for monitoring geomorphic activity. Dense 3D time series are now obtained by near-continuous terrestrial laser scanning (TLS) installations, which acquire data at high frequency (e.g. hourly) and over long periods. Such datasets contain valuable information on topographic evolution over varying spatial and temporal scales. Current analyses however are mostly conducted based on pairwise surface or object-based change, which typically require the selection of thresholds and intervals to identify the processes involved and fail to account for the full history of change. Detected change may therefore be difficult to attribute to one or more underlying geomorphic processes causing the surface alteration. We present an automatic method for 4D change analysis that includes the temporal domain by using the history of surface change to extract the period and spatial extent of changes. A 3D space-time array of surface change values is derived from an hourly TLS time series acquired at a sandy beach over five months (2967 point clouds). Change point detection is performed in the time series at individual locations and used to identify change processes, such as the appearance and disappearance of an accumulation form. These provide the seed to spatially segment ‘4D objects-by-change’ using a metric of time series similarity in a region growing approach. Results are compared to pairwise surface change for three selected cases of anthropogenic and natural processes on the beach. The obtained information reflects the evolution of a change process and its spatial extent over the change period, thereby improving upon the results of pairwise analysis. The method allows the detection and spatiotemporal delineation of even subtle changes induced by sand transport on the surface. 4D objects-by-change can therefore provide new insights on spatiotemporal characteristics of geomorphic activity, particularly in settings of continuous surfaces with dynamic morphologies.Accepted Author ManuscriptOptical and Laser Remote SensingCoastal Engineerin