728 research outputs found
Bioinformatics challenges and potentialities in studying extreme environments
- Author
- A-F Ghobakhlou
- B Bakir-Gungor
- C Angione
- C Angione
- C Angione
- C Angione
- CB Milne
- CW Knetsch
- DP Herlemann
- DT Gillespie
- E Svensson
- E Timucin
- E Timucin
- EV Koonin
- F Chiappori
- F Karlsson
- IG Romero
- J Carrera
- J Craig Venter
- JJ Faith
- JL Adrio
- JR Karr
- JT Yurkovich
- L Cardelli
- M Fondi
- M Taffi
- M Taffi
- M Yuan
- MR Meini
- O Khersonsky
- O Nolte
- P Meysman
- PJ Keeling
- R Nielsen
- S Morfopoulou
- S Pucciarelli
- S Pucciarelli
- S Sass
- SA Kauffman
- V Orlandini
- Y Zhao
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2016
- Field of study
Cold environments are populated by organisms able to contravene deleterious effects of low temperature by diverse adaptive strategies, including the production of ice binding proteins (IBPs) that inhibit the growth of ice crystals inside and outside cells. We describe the properties of such a protein (EfcIBP) identified in the metagenome of an Antarctic biological consortium composed of the ciliate Euplotes focardii and psychrophilic non-cultured bacteria. Recombinant EfcIBP can resist freezing without any conformational damage and is moderately heat stable, with a midpoint temperature of 66.4 degrees C. Tested for its effects on ice, EfcIBP shows an unusual combination of properties not reported in other bacterial IBPs. First, it is one of the best-performing IBPs described to date in the inhibition of ice recrystallization, with effective concentrations in the nanomolar range. Moreover, EfcIBP has thermal hysteresis activity (0.53 degrees C at 50 mu M) and it can stop a crystal from growing when held at a constant temperature within the thermal hysteresis gap. EfcIBP protects purified proteins and bacterial cells from freezing damage when exposed to challenging temperatures. EfcIBP also possesses a potential N-terminal signal sequence for protein transport and a DUF3494 domain that is common to secreted IBPs. These features lead us to hypothesize that the protein is either anchored at the outer cell surface or concentrated around cells to provide survival advantage to the whole cell consortium
Search for supersymmetric particles in scenarios with a gravitino LSP and stau NLSP
- Author
- Abreu P
- Adam W
- Adye T
- Adzic P
- Albrecht Z
- Alderweireld T
- Alekseev GD
- Alemany R
- Allmendinger T
- Allport PP
- Almehed S
- Amaldi U
- Amapane N
- Amato S
- Anassontzis EG
- Andersson P
- Andreazza A
- Andringa S
- Antilogus P
- Apel WD
- Arnoud Y
- Asman B
- Augustin JE
- Augustinus A
- Baillon P
- Ballestrero A
- Bambade P
- Barao F
- Barbiellini G
- Barbier R
- Bardin DY
- Barker G
- Baroncelli A
- Battaglia M
- Baubillier M
- Becks KH
- Begalli M
- Behrmann A
- Beilliere P
- Belokopytov Y
- Belous K
- Benekos NC
- Benvenuti AC
- Berat C
- Berggren M
- Bertrand D
- Besancon M
- Bilenky MS
- Bizouard MA
- Bloch D
- Blom HM
- Bonesini M
- Boonekamp M
- Booth PSL
- Borisov G
- Bosio C
- Botner O
- Boudinov E
- Bouquet B
- Bourdarios C
- Bowcock TJV
- Boyko I
- Bozovic I
- Bozzo M
- Bracko M
- Branchini P
- Brenner RA
- Bruckman P
- Brunet JM
- Bugge L
- Buran T
- Buschbeck B
- Buschmann P
- Caballero IG
- Cabrera S
- Caccia M
- Calvi M
- Camporesi T
- Canale V
- Carena F
- Carroll L
- Caso C
- Cattai A
- Cavallo FR
- Chabaud V
- Chapkin M
- Charpentier P
- Checchia P
- Chelkov GA
- Chierici R
- Chliapnikov P
- Chochula P
- Chorowicz V
- Chudoba J
- Cieslik K
- Collaboration DELPHI
- Collins P
- Contri R
- Cortina E
- Cosme G
- Cossutti F
- Costa M
- Crawley HB
- Crennell D
- Crepe S
- Crosetti G
- Czellar S
- Da Silva W
- Davenport M
- De Angelis A
- De Boer W
- De Clercq C
- De Lotto B
- De Min A
- De Paula L
- Della Ricca G
- Delpierre P
- Demaria N
- Di Ciaccio L
- Dijkstra H
- Dolbeau J
- Doroba K
- Dracos M
- Drees J
- Dris M
- Duperrin A
- Durand JD
- Eigen G
- Ekelof T
- Ekspong G
- Ellert M
- Elsing M
- Engel JP
- Fanourakis G
- Fassouliotis D
- Fayot J
- Feindt M
- Ferrer A
- Ferrer-Ribas E
- Ferro F
- Fichet S
- Firestone A
- Flagmeyer U
- Foeth H
- Fokitis E
- Fontanelli F
- Franek B
- Frodesen AG
- Fruhwirth R
- Fulda-Quenzer F
- Fuster J
- Galloni A
- Gamba D
- Gamblin S
- Gandelman M
- Garcia C
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- Gaspar C
- Gaspar M
- Gasparini U
- Gavillet P
- Gazis EN
- Gele D
- Geralis T
- Ghodbane N
- Gil I
- Gimenez MVC
- Glege F
- Gokieli R
- Golob B
- Gomez-Ceballos G
- Goncalves P
- Gopal G
- Gorn L
- Gouz Y
- Gracco V
- Grahl J
- Graziani E
- Gris P
- Grosdidier G
- Grzelak K
- Guy J
- Haag C
- Hahn F
- Hahn S
- Haider S
- Hallgren A
- Hamacher K
- Hansen J
- Harris FJ
- Hauler F
- Hedberg V
- Heising S
- Hernandez JJ
- Herquet P
- Herr H
- Hessing TL
- Heuser JM
- Higon E
- Holmgren SO
- Holt PJ
- Hoorelbeke S
- Houlden M
- Hrubec J
- Huber M
- Huet K
- Hughes GJ
- Hultqvist K
- Jackson JN
- Jacobsson R
- Jalocha P
- Janik R
- Jarlskog C
- Jarlskog G
- Jarry P
- Jean-Marie B
- Jeans D
- Johansson EK
- Jonsson P
- Joram C
- Juillot P
- Jungermann L
- Kapusta F
- Karafasoulis K
- Katsanevas S
- Katsoufis EC
- Keranen R
- Kernel G
- Kersevan BP
- Khokhlov Y
- Khomenko BA
- Khovanski NN
- Kiiskinen A
- King B
- Kinvig A
- Kjaer NJ
- Klapp O
- Klein H
- Kluit P
- Kokkinias P
- Kostioukhine V
- Kourkoumelis C
- Kouznetsov O
- Krammer M
- Kriznic E
- Krumstein Z
- Kubinec P
- Kurowska J
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- Lamsa JW
- Lane DW
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- Lepeltier V
- Lesiak T
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- Loerstad B
- Loken JG
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- Lopez-Fernandez R
- Loukas D
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- MacNaughton J
- Maestro JC
- Mahon JR
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- Malek A
- Malmgren TGM
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- Marco J
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- Mazzucato F
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- Monge MR
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- Myklebust T
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- Nielsen BS
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- Nikolenko M
- Nomokonov V
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- Oyanguren A
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- Sampsonidis D
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- Santo ME
- Schwemling P
- Schwering B
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- Segar AM
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- Sekulin R
- Shellard RC
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- Simonetto F
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- Tabarelli T
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- Thomas J
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- Vertogradov LS
- Verzi V
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- Vodopyanov AS
- Voulgaris G
- Vrba V
- Wahlen H
- Walck C
- Washbrook AJ
- Weiser C
- Wicke D
- Wickens JH
- Wilkinson GR
- Winter M
- Witek M
- Wolf G
- Yi J
- Yushchenko O
- Zalewska A
- Zalewski P
- Zavrtanik D
- Zevgolatakos E
- Zimin NI
- Zintchenko A
- Zoller P
- Zucchelli GC
- Zumerle G
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2000
- Field of study
Sleptons, neutralinos and charginos were searched for in the context of
scenarios where the lightest supersymmetric particle is the gravitino. It was
assumed that the stau is the next-to-lightest supersymmetric particle. Data
collected with the DELPHI detector at a centre-of-mass energy near 189 GeV were
analysed combining the methods developed in previous searches at lower
energies. No evidence for the production of these supersymmetric particles was
found. Hence, limits were derived at 95% confidence level.Comment: 31 pages, 14 figure
Precise measurement of the W-boson mass with the CDF II detector
- Author
- Aaltonen T.
- Abbaneo D
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- Ahmed I
- Albajar C
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- Amidei D.
- Anastassov A.
- Andreev V
- Andreev Y
- Annovi A.
- Antos J.
- Apollinari G.
- Appel J. A.
- Arce P
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- Asghar MI
- Ashmanskas W.
- Auerbach B.
- Auffray E
- Aurisano A.
- Auzinger G
- Azarkin M
- Azfar F.
- Azhgirey I
- Badgett W.
- Bae T.
- Baillon P
- Ball AH
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- Barnes V. E.
- Barnett B. A.
- Barney D
- Barria P.
- Bartos P.
- Battilana C
- Bauce M.
- Bedeschi F.
- Bedoya CF
- Beecher D.
- Behari S.
- Bell AJ
- Bellettini G.
- Bellinger J.
- Belotelov I
- Benedetti D
- Benjamin D.
- Beretvas A.
- Bernet C
- Bhatti A.
- Bialas W
- Bilinskas MJ
- Binkley M.
- Bisello D.
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- Boudreau J.
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- Yao W. -M.
- Yao W. -M.
- Yeh G. P.
- Yeh G. P.
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- Yoh J.
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- Zeng Y.
- Zhokin A
- Zhou C.
- Zucchelli S..
- Zucchelli S..ng S
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2012
- Field of study
We have measured the W-boson mass MW using data corresponding to 2.2/fb of
integrated luminosity collected in proton-antiproton collisions at 1.96 TeV
with the CDF II detector at the Fermilab Tevatron collider. Samples consisting
of 470126 W->enu candidates and 624708 W->munu candidates yield the measurement
MW = 80387 +- 12 (stat) +- 15 (syst) = 80387 +- 19 MeV. This is the most
precise measurement of the W-boson mass to date and significantly exceeds the
precision of all previous measurements combined
X-ray emission from the Sombrero galaxy: discrete sources
- Author
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
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- Wittich P
- Wittmer B
- Wohri HK
- Wolf R
- Womersley WJ
- Won S
- Wood D
- Wood JS
- Worm SD
- Wright D
- Wrochna G
- Wu JH
- Wu W
- Wulz CE
- Wurthwein F
- Wyslouch B
- Xiao H
- Xie S
- Xu M
- Yagil A
- Yan M
- Yang F
- Yang M
- Yang M
- Yang Y
- Yang ZC
- Yazgan E
- Yelton J
- Yetkin T
- Yi K
- Yildirim E
- Yilmaz Y
- Yohay R
- Yoo HD
- Yoon AS
- York A
- Yu I
- Yu SS
- Yumiceva F
- Yun JC
- Zabel J
- Zabi A
- Zablocki J
- Zaganidis N
- Zakaria M
- Zalewski P
- Zanetti M
- Zang J
- Zang SL
- Zarubin A
- Zatserklyaniy A
- Zeinali M
- Zeise M
- Zeuner WD
- Zeyrek M
- Zhang J
- Zhang L
- Zhang Z
- Zheng Y
- Zhokin A
- Zhu B
- Zhu RY
- Zhukov V
- Zhukova V
- Ziebarth EB
- Ziegler J
- Zielinski M
- Zito G
- Zoeller MH
- Zorbilmez C
- Zotto P
- Zou W
- Zumerle G
- Zuranski A
- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2010
- Field of study
We present a study of discrete X-ray sources in and around the
bulge-dominated, massive Sa galaxy, Sombrero (M104), based on new and archival
Chandra observations with a total exposure of ~200 ks. With a detection limit
of L_X = 1E37 erg/s and a field of view covering a galactocentric radius of ~30
kpc (11.5 arcminute), 383 sources are detected. Cross-correlation with Spitler
et al.'s catalogue of Sombrero globular clusters (GCs) identified from HST/ACS
observations reveals 41 X-rays sources in GCs, presumably low-mass X-ray
binaries (LMXBs). We quantify the differential luminosity functions (LFs) for
both the detected GC and field LMXBs, whose power-low indices (~1.1 for the
GC-LF and ~1.6 for field-LF) are consistent with previous studies for
elliptical galaxies. With precise sky positions of the GCs without a detected
X-ray source, we further quantify, through a fluctuation analysis, the GC LF at
fainter luminosities down to 1E35 erg/s. The derived index rules out a
faint-end slope flatter than 1.1 at a 2 sigma significance, contrary to recent
findings in several elliptical galaxies and the bulge of M31. On the other
hand, the 2-6 keV unresolved emission places a tight constraint on the field
LF, implying a flattened index of ~1.0 below 1E37 erg/s. We also detect 101
sources in the halo of Sombrero. The presence of these sources cannot be
interpreted as galactic LMXBs whose spatial distribution empirically follows
the starlight. Their number is also higher than the expected number of cosmic
AGNs (52+/-11 [1 sigma]) whose surface density is constrained by deep X-ray
surveys. We suggest that either the cosmic X-ray background is unusually high
in the direction of Sombrero, or a distinct population of X-ray sources is
present in the halo of Sombrero.Comment: 11 figures, 5 tables, ApJ in pres
Performance of the CMS Cathode Strip Chambers with Cosmic Rays
- Author
- Abadjiev K
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
- Abelev B
- Acosta D
- Acosta JG
- Acosta MV
- Actis O
- Adam N
- Adam W
- Adams MR
- Adams T
- Adiguzel A
- Adler V
- Adolphi R
- Adzic P
- Afaq MA
- Agostino L
- Agram JL
- Aguilar-Benitez M
- Ahmad M
- Ahmad WH
- Ahmed I
- Ahmed W
- Ahuja S
- Aisa D
- Aisa S
- Akchurin N
- Akgun B
- Akgun U
- Akimenko S
- Akin IV
- Alagoz E
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- Albayrak EA
- Alberdi J
- Albergo S
- Albert E
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- Alidra M
- Aliev T
- Allfrey P
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- Altenhofer G
- Altsybeev I
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- Alves GA
- Amaglobeli N
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- Ambroglini F
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- Andelin D
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- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2009
- Field of study
The Cathode Strip Chambers (CSCs) constitute the primary muon tracking device
in the CMS endcaps. Their performance has been evaluated using data taken
during a cosmic ray run in fall 2008. Measured noise levels are low, with the
number of noisy channels well below 1%. Coordinate resolution was measured for
all types of chambers, and fall in the range 47 microns to 243 microns. The
efficiencies for local charged track triggers, for hit and for segments
reconstruction were measured, and are above 99%. The timing resolution per
layer is approximately 5 ns
Search for R-parity-violating supersymmetry in events with four or more leptons in sqrt(s) =7 TeV pp collisions with the ATLAS detector
- Author
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- Yamamoto S
- Yamamura T
- Yamanaka T
- Yamazaki T
- Yamazaki Y
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- Yang UK
- Yang Y
- Yang Z
- Yanush S
- Yao L
- Yao Y
- Yasu Y
- Smit GVY
- Ye J
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- Yilmaz M
- Yoosoofmiya R
- Yorita K
- Yoshida R
- Yoshihara K
- Young C
- Young CJ
- Youssef S
- Yu D
- Yu DR
- Yu J
- Yu J
- Yuan L
- Yurkewicz A
- Zabinski B
- Zaidan R
- Zaitsev AM
- Zajacova Z
- Zanello L
- Zanzi D
- Zaytsev A
- Zeitnitz C
- Zeman M
- Zemla A
- Zendler C
- Zenin O
- Zenis T
- Zinonos Z
- Zerwas D
- della Porta GZ
- Zhang D
- Zhang H
- Zhang J
- Zhang X
- Zhang Z
- Zhao L
- Zhao Z
- Zhemchugov A
- Zhong J
- Zhou B
- Zhou N
- Zhou Y
- Zhu CG
- Zhu H
- Zhu J
- Zhu Y
- Zhuang X
- Zhuravlov V
- Zibell A
- Zieminska D
- Zimin NI
- Zimmermann R
- Zimmermann S
- Zimmermann S
- Ziolkowski M
- Zitoun R
- Zivkovic L
- Zmouchko VV
- Zobernig G
- Zoccoli A
- zur Nedden M
- Zutshi V
- Zwalinski L
- Collaboration ATLAS
- Publication venue
- Springer Verlag
- Publication date
- 01/01/2008
- Field of study
A search for new phenomena in final states with four or more leptons (electrons or muons) is presented. The analysis is based on 4.7 fb−1 of s=7TeV proton-proton collisions delivered by the Large Hadron Collider and recorded with the ATLAS detector. Observations are consistent with Standard Model expectations in two signal regions: one that requires moderate values of missing transverse momentum and another that requires large effective mass. The results are interpreted in a simplified model of R-parity-violating supersymmetry in which a 95% CL exclusion region is set for charged wino masses up to 540 GeV. In an R-parity-violating MSUGRA/CMSSM model, values of m 1/2 up to 820 GeV are excluded for 10 < tan β < 40
Search for high-mass resonances decaying to dilepton final states in pp collisions at s√=7 TeV with the ATLAS detector
- Author
- Aad G
- Abajyan T
- Abbott B
- Abdallah J
- Abdelalim AA
- Abdinov O
- Aben R
- Abi B
- Abolins M
- AbouZeid OS
- Abramowicz H
- Abreu H
- Acharya BS
- Adamczyk L
- Adams DL
- Addy TN
- Adelman J
- Adomeit S
- Adragna P
- Adye T
- Aefsky S
- Aguilar-Saavedra JA
- Agustoni M
- Aharrouche M
- Ahlen SP
- Ahles R
- Ahmad A
- Ahsan M
- Aielli G
- Akesson TPA
- Akimoto G
- Akimov AV
- Alam MA
- Alam MS
- Albert J
- Albrand S
- Aleksa M
- Aleksandrov IN
- Alessandria F
- Alexa C
- Alexander G
- Alexandre G
- Alexopoulos T
- Alhroob M
- Aliev M
- Alimonti G
- Alison J
- Allbrooke BMM
- Allport PP
- Allwood-Spiers SE
- Almenar CC
- Almond J
- Aloisio A
- Alon R
- Alonso A
- Alonso F
- Altheimer A
- Alviggi MG
- Amako K
- Amelung C
- Ammosov VV
- Amor Dos Santos SP
- Amorim A
- Amram N
- Anastopoulos C
- Ancu LS
- Andari N
- Andeen T
- Anders CF
- Anders G
- Anderson KJ
- Andreazza A
- Andrei V
- Andrieux M-L
- Anduaga XS
- Angelidakis S
- Anger P
- Angerami A
- Anghinolfi F
- Anh TV
- Anisenkov A
- Anjos N
- Annovi A
- Antonaki A
- Antonelli M
- Antonov A
- Antos J
- Anulli F
- Aoki M
- Aoun S
- Apolle R
- Arabidze G
- Aracena I
- Arai Y
- Arce ATH
- Arfaoui S
- Arguin J-F
- Argyropoulos S
- Arik E
- Arik M
- Armbruster AJ
- Arnaez O
- Arnal V
- Arnault C
- Artamonov A
- Artoni G
- Arutinov D
- Asai S
- Ask S
- Asman B
- Asquith L
- Assamagan K
- Astbury A
- Atkinson M
- Aubert B
- Auge E
- Augsten K
- Aurousseau M
- Avolio G
- Avramidou R
- Axen D
- Azuelos G
- Azuma Y
- Baak MA
- Baccaglioni G
- Bacci C
- Bach AM
- Bachacou H
- Bachas K
- Backes M
- Backhaus M
- Badescu E
- Bagnaia P
- Bahinipati S
- Bai Y
- Bailey DC
- Bain T
- Baines JT
- Baker MD
- Baker OK
- Baker S
- Balek P
- Banas E
- Banerjee P
- Banerjee S
- Banfi D
- Bangert A
- Bansal V
- Bansil HS
- Barajas CAC
- Barak L
- Baranov SP
- Barber T
- Barberio EL
- Barberis D
- Barbero M
- Bardin DY
- Barillari T
- Barisonzi M
- Barklow T
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- Barnett BM
- Barnett RM
- Baroncelli A
- Barone G
- Barr AJ
- Barreiro F
- Barrera CO
- Barrillon P
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- Turecek D
- Turlay E
- Turra R
- Tuts PM
- Tykhonov A
- Tylmad M
- Tyndel M
- Tzanakos G
- Uchida K
- Ueda I
- Ueno R
- Ugland M
- Uhlenbrock M
- Uhrmacher M
- Ukegawa F
- Unal G
- Undrus A
- Unel G
- Unno Y
- Urbaniec D
- Urquijo P
- Usai G
- Uslenghi M
- Vacavant L
- Vacek V
- Vachon B
- Vague FV
- Vahsen S
- Valenta J
- Valentinetti S
- Valero A
- Valkar S
- Valladolid Gallego E
- Vallecorsa S
- Valls Ferrer JA
- Van Berg R
- Van der Deijl PC
- van der Geer R
- van der Graaf H
- van der Leeuw R
- van der Poe E
- van der Ster D
- van Eldik N
- van Gemmeren P
- van Huysduynen LH
- van Vulpen I
- Vanadia M
- Vandelli W
- Vaniachine A
- Vankov P
- Vannucci F
- Vari R
- Varnes EW
- Varol T
- Varouchas D
- Vartapetian A
- Varvell KE
- Vassilakopoulos VI
- Vazeille F
- Vazquez JGP
- Vegni G
- Veillet JI
- Veloso F
- Veness R
- Veneziano S
- Ventura A
- Ventura D
- Venturi M
- Venturi N
- Vercesi V
- Verducci M
- Verkerke W
- Vermeulen JC
- Vest A
- Vetterli MC
- Vichou I
- Vickey T
- Viehhauser GHA
- Viel S
- Villa M
- Villaplana Perez M
- Vilucchi E
- Vincter MG
- Vinek E
- Vinogradov VB
- Virchaux M
- Virzi J
- Vitells O
- Viti M
- Vivarelli I
- Vlachos S
- Vladoiu D
- Vlasak M
- Vogel A
- Vokac P
- Volpi G
- Volpi M
- Volpini G
- von der Schmitt H
- von Radziewski H
- von Toerne E
- Vorobel V
- Vorwerk V
- Vos M
- Voss R
- Voss TT
- Vossebeld JH
- Vranjes N
- Vrba V
- Vreeswijk M
- Vuillermet R
- Vukotic I
- Wagner P
- Wagner W
- Wahlen H
- Wahrmund S
- Wakabayashi J
- Walch S
- Walder J
- Walker R
- Walkowiak W
- Wall R
- Waller P
- Walsh B
- Wang C
- Wang H
- Wang H
- Wang J
- Wang J
- Wang R
- Wang SM
- Wang T
- Warburton A
- Ward CP
- Wardrope DR
- Warsinsky M
- Washbrook A
- Wasicki C
- Watanabe I
- Watkins PM
- Watson AT
- Watson IJ
- Watson MF
- Watts G
- Watts S
- Waugh AT
- Waugh BM
- Weber MS
- Webster JS
- Weidberg AR
- Weigell P
- Weingarten J
- Weiser C
- Wells PS
- Wemans ADV
- Wenaus T
- Wendland D
- Wengler T
- Wengu Z
- Wenig S
- Wermes N
- Werner M
- Werner P
- Werth M
- Wessels M
- Wetter J
- Weydert C
- Whalen K
- White A
- White MJ
- White S
- Whitehead SR
- Whiteson D
- Whittington D
- Wicek F
- Wicke D
- Wickens FJ
- Wiedenmann W
- Wielers M
- Wienemann P
- Wiglesworth C
- Wiik-Fuchs LAM
- Wijeratne PA
- Wildauer A
- Wildt MA
- Wilhelm I
- Wilkens HG
- Will JZ
- Williams E
- Williams HH
- Willis W
- Willocoq S
- Wilson A
- Wilson JA
- Wilson MG
- Wingerter-Seez I
- Winkelmann S
- Winklmeier F
- Wittgen M
- Wollstadt SJ
- Wolter MW
- Wolters H
- Wong WC
- Wooden G
- Wosiek BK
- Wotschack J
- Woudstra MJ
- Wozniak KW
- Wraight K
- Wright M
- Wrona B
- Wu SL
- Wu X
- Wu Y
- Wulf E
- Wynne BM
- Xella S
- Xiao M
- Xie S
- Xu C
- Xu D
- Xu L
- Yabsley B
- Yacoob S
- Yagci KD
- Yamada M
- Yamaguchi H
- Yamamoto A
- Yamamoto K
- Yamamoto S
- Yamamura T
- Yamanaka T
- Yamazaki T
- Yamazaki Y
- Yan Z
- Yang H
- Yang UK
- Yang Y
- Yang Z
- Yanush S
- Yao L
- Yao Y
- Yasu Y
- Ye J
- Ye S
- Yildiz HD
- Yilmaz M
- Yoosoofmiya R
- Yorita K
- Yoshida R
- Yoshihara K
- Young C
- Young CJ
- Youssef S
- Yu D
- Yu DR
- Yu J
- Yu J
- Yuan L
- Yurkewicz A
- Zabinski B
- Zaidan R
- Zaitsev AM
- Zajacova Z
- Zanello L
- Zanzi D
- Zaytsev A
- Zeitnitz C
- Zeman M
- Zemla A
- Zendler C
- Zenin O
- Zenis T
- Zerwas D
- Zhang D
- Zhang H
- Zhang J
- Zhang X
- Zhang Z
- Zhao L
- Zhao Z
- Zhemchugov A
- Zhong J
- Zhou B
- Zhou N
- Zhou Y
- Zhu CG
- Zhu H
- Zhu J
- Zhu Y
- Zhuang X
- Zhuravlov V
- Zibell A
- Zieminska D
- Zimin NI
- Zimmermann R
- Zimmermann S
- Zimmermann S
- Zinonos Z
- Ziolkowski M
- Zitoun R
- Zivkovic L
- Zmouchko VV
- Zobernig G
- Zoccoli A
- zur Nedden M
- Zutshi V
- Zwalinski L
- Publication venue
- Springer
- Publication date
- 23/11/2012
- Field of study
The ATLAS detector at the Large Hadron Collider is used to search for high-mass resonances decaying to an electron-positron pair or a muon-antimuon pair. The search is sensitive to heavy neutral Z′ gauge bosons, Randall-Sundrum gravitons, Z * bosons, techni-mesons, Kaluza-Klein Z/γ bosons, and bosons predicted by Torsion models. Results are presented based on an analysis of pp collisions at a center-of-mass energy of 7 TeV corresponding to an integrated luminosity of 4.9 fb−1 in the e + e − channel and 5.0 fb−1 in the μ + μ −channel. A Z ′ boson with Standard Model-like couplings is excluded at 95 % confidence level for masses below 2.22 TeV. A Randall-Sundrum graviton with coupling k/MPl=0.1 is excluded at 95 % confidence level for masses below 2.16 TeV. Limits on the other models are also presented, including Technicolor and Minimal Z′ Models
Adverse Events Post Smallpox-Vaccination: Insights from Tail Scarification Infection in Mice with Vaccinia virus
- Author
- A Sette
- B Moss
- B Puissant-Lubrano
- BE Mota
- Bruno E. F. Mota
- Cláudio A. Bonjardim
- Darin Carroll
- Dipshikha Chakravortty
- DJ Esteban
- EJ Freyschmidt
- EM Pantelouris
- Erna G. Kroon
- FHD Fenner
- Flávio G. da Fonseca
- G Chaudhri
- G Karupiah
- Giliane Trindade
- IG Sakala
- IM Belyakov
- Inger K. Damon
- J Neyts
- JC Ramirez
- K Kohno
- Kevin Karem
- L Liu
- Leda Q. Vieira
- LP Perera
- M Bray
- M Fang
- M Worthington
- M. Shannon Keckler
- MA Brundler
- Marco A. Campos
- MD Howell
- MK Spriggs
- MM Gherardi
- MS Rolph
- N Harris
- N Orr
- Nadia Gallardo-Romero
- P Mombaerts
- Paulo C. P. Ferreira
- PP Mortimer
- R Xu
- RH Xu
- RM Vorou
- S Kohyama
- S Lustig
- S Melamed
- S Parker
- T Saito
- T Tian
- V Panchanathan
- VA Fulginiti
- Y Edghill-Smith
- Y Kawakami
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2011
- Field of study
Adverse events upon smallpox vaccination with fully-replicative strains of Vaccinia virus (VACV) comprise an array of clinical manifestations that occur primarily in immunocompromised patients leading to significant host morbidity/mortality. The expansion of immune-suppressed populations and the possible release of Variola virus as a bioterrorist act have given rise to concerns over vaccination complications should more widespread vaccination be reinitiated. Our goal was to evaluate the components of the host immune system that are sufficient to prevent morbidity/mortality in a murine model of tail scarification, which mimics immunological and clinical features of smallpox vaccination in humans. Infection of C57BL/6 wild-type mice led to a strictly localized infection, with complete viral clearance by day 28 p.i. On the other hand, infection of T and B-cell deficient mice (Rag1−/−) produced a severe disease, with uncontrolled viral replication at the inoculation site and dissemination to internal organs. Infection of B-cell deficient animals (µMT) produced no mortality. However, viral clearance in µMT animals was delayed compared to WT animals, with detectable viral titers in tail and internal organs late in infection. Treatment of Rag1−/− with rabbit hyperimmune anti-vaccinia serum had a subtle effect on the morbidity/mortality of this strain, but it was effective in reduce viral titers in ovaries. Finally, NUDE athymic mice showed a similar outcome of infection as Rag1−/−, and passive transfer of WT T cells to Rag1−/− animals proved fully effective in preventing morbidity/mortality. These results strongly suggest that both T and B cells are important in the immune response to primary VACV infection in mice, and that T-cells are required to control the infection at the inoculation site and providing help for B-cells to produce antibodies, which help to prevent viral dissemination. These insights might prove helpful to better identify individuals with higher risk of complications after infection with poxvirus
Adaptation of peroxisome proliferator-activated receptor alpha to hibernation in bats
- Author
- A Doetzlhofer
- AJ Meijer
- AT Chinwalla
- B Desvergne
- B Lin
- BD Reed
- C Bernal-Mizrachi
- C Blanquart
- C Dreyer
- C-A Lim
- CJ Nelson
- CK Glass
- CP Lyman
- D Brawand
- Dong Dong
- EC Teeling
- F Geiser
- F Geiser
- G Zhang
- GS Hotamisligil
- Guantao Zheng
- H Carey
- HK Srere
- HV Carey
- I Romero-Calvo
- IG Romero
- IV Kulakovskiy
- J Berger
- J Felsenstein
- JD Thompson
- JN Feige
- JP Katz
- K Tamura
- KB Storey
- KJ Livak
- KM Wadosky
- L Yuan
- M Megraw
- M Thomas-Chollier
- ME Allan
- MT Andrews
- N Simmons
- NS Tan
- P Morin Jr
- P Yaqoob
- PJ Wittkopp
- R Martinelli
- RD Barber
- RG Melvin
- S Kersten
- SD Clarke
- SF Eddy
- SF Eddy
- SF Eddy
- Shuyi Zhang
- T Garland
- T Garland
- T Inagaki
- TD Schmittgen
- Tianxiao Yang
- W Wahli
- WJ Murphy
- WS Lim
- X Zhou
- Y Xu
- YH Pan
- Yi-Hsuan Pan
- Yijie Han
- Z El Kebbaj
- Z Yang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
- …