2 research outputs found
Importancia del uso de simuladores educativos para la formación de estudiantes de ingeniería
El presente trabajo, demuestra la importancia del uso de simuladores educativos en la formación de estudiantes, mediante un análisis referencial del estado del arte, la fundamentación teórica y un estudio de campo, basado en una encuesta aplicada a los alumnos de la carrera de Ingeniería en Control y Automatización (ICA), para determinar las ventajas y desventajas propuestas por diferentes autores y por las experiencias de los estudiantes encuestados, así como los programas de simulación más versátiles y utilizados en el área de estudio. De acuerdo a los resultados, se tiene que hay una gran variedad de software en el mercado de uso didáctico e industrial, lo que también facilita su uso, además de que se pudo comprobar que son herramientas necesarias para el análisis y el diseño de sistemas de diferente índole, así como para la formación de recursos humanos en general, y que debería ser una opción para resolver la falta de laboratorios en las escuelas, por cuestiones pedagógicas, económicas y de infraestructura.This paper, show the importance of the use of educational simulators in the formation of students, through a referential analysis of the theoretical foundation and a field study, based on a survey applied to the students of the Engineering in Control and Automation, obtaining the advantages and disadvantages proposed by different authors and by the students surveyed. Obtaining which are the most versatile simulation software and used in the study area, as well as the variety that exists in the didactic and industrial use market, confirming that the use of simulators, is a necessary tool for the analysis, the design of systems of different nature, proving that it improves the training of human resources in general, and that it should be an option to salve the lack of laboratories in schools, due to economic and infrastructure issues
Guidelines for the use of flow cytometry and cell sorting in immunological studies
International audienceThe classical model of hematopoiesis established in the mouse postulates that lymphoid cells originate from a founder population of common lymphoid progenitors. Here, using a modeling approach in humanized mice, we showed that human lymphoid development stemmed from distinct populations of CD127(-) and CD127(+) early lymphoid progenitors (ELPs). Combining molecular analyses with in vitro and in vivo functional assays, we demonstrated that CD127(-) and CD127(+) ELPs emerged independently from lympho-mono-dendritic progenitors, responded differently to Notch1 signals, underwent divergent modes of lineage restriction, and displayed both common and specific differentiation potentials. Whereas CD127(-) ELPs comprised precursors of T cells, marginal zone B cells, and natural killer (NK) and innate lymphoid cells (ILCs), CD127(+) ELPs supported production of all NK cell, ILC, and B cell populations but lacked T potential. On the basis of these results, we propose a "two-family" model of human lymphoid development that differs from the prevailing model of hematopoiesis