CLASSIFICATION OF PARKINSON'S DISEASE IN BRAIN MRI IMAGES USING DEEP RESIDUAL CONVOLUTIONAL NEURAL NETWORK

In our aging culture, neurodegenerative disorders like Parkinson's disease (PD) are among the most serious health issues. It is a neurological condition that has social and economic effects on individuals. It happens because the brain's dopamine-producing cells are unable to produce enough of the chemical to support the body's motor functions. The main symptoms of this illness are eyesight, excretion activity, speech, and mobility issues, followed by depression, anxiety, sleep issues, and panic attacks. The main aim of this research is to develop a workable clinical decision-making framework that aids the physician in diagnosing patients with PD influence. In this research, we proposed a technique to classify Parkinson’s disease by MRI brain images. Initially, normalize the input data using the min-max normalization method and then remove noise from input images using a median filter. Then utilizing the Binary Dragonfly Algorithm to select the features. Furthermore, to segment the diseased part from MRI brain images using the technique Dense-UNet. Then, classify the disease as if it’s Parkinson’s disease or health control using the Deep Residual Convolutional Neural Network (DRCNN) technique along with Enhanced Whale Optimization Algorithm (EWOA) to get better classification accuracy. Here, we use the public Parkinson’s Progression Marker Initiative (PPMI) dataset for Parkinson’s MRI images. The accuracy, sensitivity, specificity, and precision metrics will be utilized with manually gathered data to assess the efficacy of the proposed methodology

Large expert-curated database for benchmarking document similarity detection in biomedical literature search

Document recommendation systems for locating relevant literature have mostly relied on methods developed a decade ago. This is largely due to the lack of a large offline gold-standard benchmark of relevant documents that cover a variety of research fields such that newly developed literature search techniques can be compared, improved and translated into practice. To overcome this bottleneck, we have established the RElevant LIterature SearcH consortium consisting of more than 1500 scientists from 84 countries, who have collectively annotated the relevance of over 180 000 PubMed-listed articles with regard to their respective seed (input) article/s. The majority of annotations were contributed by highly experienced, original authors of the seed articles. The collected data cover 76% of all unique PubMed Medical Subject Headings descriptors. No systematic biases were observed across different experience levels, research fields or time spent on annotations. More importantly, annotations of the same document pairs contributed by different scientists were highly concordant. We further show that the three representative baseline methods used to generate recommended articles for evaluation (Okapi Best Matching 25, Term Frequency-Inverse Document Frequency and PubMed Related Articles) had similar overall performances. Additionally, we found that these methods each tend to produce distinct collections of recommended articles, suggesting that a hybrid method may be required to completely capture all relevant articles. The established database server located at https://relishdb.ict.griffith.edu.au is freely available for the downloading of annotation data and the blind testing of new methods. We expect that this benchmark will be useful for stimulating the development of new powerful techniques for title and title/abstract-based search engines for relevant articles in biomedical research.Peer reviewe

CLASSIFICATION OF PARKINSON'S DISEASE IN BRAIN MRI IMAGES USING DEEP RESIDUAL CONVOLUTIONAL NEURAL NETWORK (DRCNN)

In our aging culture, neurodegenerative disorders like Parkinson's disease (PD) are among the most serious health issues. It is a neurological condition that has social and economic effects on individuals. It happens because the brain's dopamine-producing cells are unable to produce enough of the chemical to support the body's motor functions. The main symptoms of this illness are eyesight, excretion activity, speech, and mobility issues, followed by depression, anxiety, sleep issues, and panic attacks. The main aim of this research is to develop a workable clinical decision-making framework that aids the physician in diagnosing patients with PD influence. In this research, the authors propose a technique to classify Parkinson’s disease by MRI brain images. Initially, the input data is normalized using the min-max normalization method, and then noise is removed from the input images using a median filter. The Binary Dragonfly algorithm is then used to select features. In addition, the Dense-UNet technique is used to segment the diseased part from brain MRI images. The disease is then classified as Parkinson's disease or health control using the Deep Residual Convolutional Neural Network (DRCNN) technique along with the Enhanced Whale Optimization Algorithm (EWOA) to achieve better classification accuracy. In this work, the Parkinson's Progression Marker Initiative (PPMI) public dataset for Parkinson's MRI images is used. Indicators of accuracy, sensitivity, specificity and precision are used with manually collected data to evaluate the effectiveness of the proposed methodology