251 research outputs found
Herniorrafia inguinal com anestesia local em regime ambulatorial
- Author
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Health Journalism Internships: A Social Marketing Strategy to Address Health Disparities
- Author
- A Andreasen
- A Bandura
- A Ries
- A Sun
- AA Berger
- AE Maxwell
- AF Jerant
- BA Guadagnolo
- BC Jacoby
- BH Marcus
- BN Leistikow
- C Frost
- CA Caburnay
- CN Jenkins
- D Reah
- DJ Hu
- Duy H. Nguyen
- EA Brawley
- Georgia Robins Sadler
- GR Sadler
- GR Sadler
- H Vries De
- Helen Shi Stafford
- I Ajzen
- J Berry
- J Foster
- J Prochaska
- JC Levinson
- JR Hebert
- K Glanz
- LM Wallack
- M Fishbein
- M Gladwell
- M Hughes
- M Terplan
- M Yudkin
- MA Jim
- MS Ruiz
- MW Kreuter
- NK Janz
- NW Ottenritter
- P Kotler
- PN Bloom
- R Keyes
- RW Bly
- S Godin
- S Godin
- SC Duerksen
- SH Priest
- SJ Curry
- SK Willsie
- SL Gomez
- SR Kaskowitz 3rd
- SS Coughlin
- Suzuho Shimasaki
- T O'Sullivan
- W Samady
- Publication venue
- Springer-Verlag
- Publication date
- 01/01/2010
- Field of study
The USA seeks to eliminate health disparities by stimulating the rapid uptake of health-promoting behaviors within disadvantaged communities. A health journalism internship incorporates social marketing strategies to increase communities' access to cancer information, while helping the interns who are recruited from underrepresented communities gain admission to top graduate schools. Interns are taught basic health journalism skills that enable them to create immediate streams of cancer-related press releases for submission to community newspapers. Interns are charged with the social responsibility of continuing this dissemination process throughout their careers. Intermediate outcomes are measured as mediators of distal behavioral change goals
Search for squarks and gluinos in events with isolated leptons, jets and missing transverse momentum at s√=8 TeV with the ATLAS detector
- Author
- A Djouadi
- A Kulesza
- A Kulesza
- A Lazopoulos
- A Neveu
- A Neveu
- A Sherstnev
- A. A. E. Bannoura
- A. A. Elliot
- A. A. Grillo
- A. A. Komar
- A. A. Korol
- A. A. Maier
- A. A. Minaenko
- A. A. Nepomuceno
- A. A. Snesarev
- A. A. Solodkov
- A. A. Talyshev
- A. Aloisio
- A. Alonso
- A. Altheimer
- A. Amorim
- A. Andreazza
- A. Angerami
- A. Annovi
- A. Antonov
- A. Artamonov
- A. Ashkenazi
- A. B. Fenyuk
- A. Baroncelli
- A. Bassalat
- A. Basye
- A. Beddall
- A. Bellerive
- A. Bingul
- A. Bocci
- A. Bogouch
- A. Borisov
- A. Boveia
- A. Brandt
- A. Bruni
- A. Buzatu
- A. C. Bundock
- A. C. Daniells
- A. C. König
- A. C. Martyniuk
- A. C. Schaffer
- A. Calandri
- A. Campoverde
- A. Canepa
- A. Castelli
- A. Catinaccio
- A. Cattai
- A. Cerri
- A. Cervelli
- A. Chafaq
- A. Chegwidden
- A. Cheplakov
- A. Chilingarov
- A. Chitan
- A. Ciocio
- A. Clark
- A. Coccaro
- A. Corso-Radu
- A. Cortes-Gonzalez
- A. D. Hawkins
- A. D. Pilkington
- A. Dafinca
- A. Dattagupta
- A. De Salvo
- A. De Santo
- A. Dell’Acqua
- A. Demilly
- A. Dewhurst
- A. Di Ciaccio
- A. Di Domenico
- A. Di Girolamo
- A. Di Mattia
- A. Di Simone
- A. Dimitrievska
- A. Doria
- A. Dudarev
- A. Durglishvili
- A. E. Baas
- A. E. Barton
- A. E. Kiryunin
- A. E. Loevschall-Jensen
- A. Ereditato
- A. Ezhilov
- A. F. Saavedra
- A. Farbin
- A. Farilla
- A. Favareto
- A. Ferrari
- A. Ferrer
- A. Ferretto Parodi
- A. Filipčič
- A. Firan
- A. Fischer
- A. Floderus
- A. Formica
- A. Forti
- A. G. Bogdanchikov
- A. G. Buckley
- A. G. Goussiou
- A. G. Leister
- A. G. Myagkov
- A. G. Olchevski
- A. Gabrielli
- A. Gabrielli
- A. Gemmell
- A. Gershon
- A. Glazov
- A. Gomes
- A. Gorišek
- A. Grohsjean
- A. Haas
- A. Hamilton
- A. Hasib
- A. Henrichs
- A. Hoecker
- A. Hoummada
- A. Hrynevich
- A. I. Butt
- A. I. Etienvre
- A. I. Mincer
- A. Irles Quiles
- A. J. Armbruster
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- A. Juste Rozas
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- A. Kapliy
- A. Karamaoun
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- A. Khanov
- A. Kharlamov
- A. Khodinov
- A. Khomich
- A. Klimentov
- A. Knue
- A. Korn
- A. Kotwal
- A. Kourkoumeli-Charalampidi
- A. Koutsman
- A. Krasznahorkay
- A. Kravchenko
- A. Kruse
- A. Kugel
- A. Kuhl
- A. Kupco
- A. L. Maslennikov
- A. L. Read
- A. L. S. Schorlemmer
- A. L. Yen
- A. La Rosa
- A. Lehan
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- A. Lounis
- A. Lucotte
- A. M. Cooper-Sarkar
- A. M. Henriques Correia
- A. M. Leyko
- A. M. Litke
- A. M. Nairz
- A. M. Soukharev
- A. M. Zaitsev
- A. Macchiolo
- A. Madsen
- A. Maevskiy
- A. Maio
- A. Manfredini
- A. Mann
- A. Manousakis-Katsikakis
- A. Marzin
- A. Mastroberardino
- A. McCarn
- A. Mehta
- A. Mengarelli
- A. Messina
- A. Milic
- A. Milov
- A. Miucci
- A. Morton
- A. N. Karyukhin
- A. N. Sisakyan
- A. N. Tuna
- A. Nagarkar
- A. Negri
- A. Nelson
- A. Nikiforov
- A. Nisati
- A. Ochi
- A. Oh
- A. Olariu
- A. Olszewski
- A. Onofre
- A. Ouraou
- A. Ovcharova
- A. P. Colijn
- A. Pacheco Pages
- A. Palma
- A. Paramonov
- A. Passeri
- A. Petridis
- A. Picazio
- A. Pinder
- A. Pingel
- A. Policicchio
- A. Polini
- A. Poppleton
- A. Pranko
- A. Quadt
- A. Qureshi
- A. R. Davison
- A. R. Stradling
- A. R. Weidberg
- A. Redelbach
- A. Renaud
- A. Rimoldi
- A. Robichaud-Veronneau
- A. Robson
- A. Romaniouk
- A. Rozanov
- A. Ruiz-Martinez
- A. Ruschke
- A. S. Boldyrev
- A. S. Cerqueira
- A. S. Chisholm
- A. S. Hard
- A. S. Kozhin
- A. S. Mete
- A. S. Thompson
- A. Saddique
- A. Salamon
- A. Salnikov
- A. Salvucci
- A. Salzburger
- A. Sanchez
- A. Sansoni
- A. Sapronov
- A. Sbrizzi
- A. Schoening
- A. Schwartzman
- A. Seiden
- A. Sfyrla
- A. Shcherbakova
- A. Shmeleva
- A. Sidoti
- A. Sircar
- A. Soffer
- A. Soloshenko
- A. Sood
- A. Sopczak
- A. Straessner
- A. Strandlie
- A. Strubig
- A. Succurro
- A. T. Doyle
- A. T. Goshaw
- A. T. H. Arce
- A. T. Law
- A. T. Watson
- A. Taffard
- A. Tavares Delgado
- A. Tricoli
- A. Trzupek
- A. Tudorache
- A. Tykhonov
- A. Undrus
- A. Usanova
- A. V. Akimov
- A. V. Anisenkov
- A. Valero
- A. Vaniachine
- A. Vartapetian
- A. Ventura
- A. Venturini
- A. Vest
- A. Vogel
- A. Warburton
- A. Washbrook
- A. White
- A. Wildauer
- A. Wilson
- A. Yamamoto
- A. Yurkewicz
- A. Zaman
- A. Zemla
- A. Zhemchugov
- A. Zibell
- A. Zoccoli
- AH Chamseddine
- AL Read
- ATLAS collaboration
- ATLAS collaboration
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- ATLAS collaboration
- ATLAS collaboration
- ATLAS collaboration
- ATLAS collaboration
- ATLAS collaboration
- ATLAS collaboration
- ATLAS collaboration
- ATLAS collaboration
- ATLAS collaboration
- ATLAS collaboration
- ATLAS collaboration
- ATLAS collaboration
- ATLAS collaboration
- ATLAS collaboration
- ATLAS collaboration
- ATLAS collaboration
- ATLAS collaboration
- ATLAS collaboration
- ATLAS collaboration
- ATLAS collaboration
- B Cooper
- B. A. Dolgoshein
- B. A. Long
- B. A. Petersen
- B. A. Schumm
- B. Abbott
- B. Abi
- B. Alvarez Gonzalez
- B. Auerbach
- B. Axen
- B. B. Tannenwald
- B. Brau
- B. Brelier
- B. Burghgrave
- B. Butler
- B. C. Cerio
- B. Chapleau
- B. Cole
- B. D. Cooper
- B. D. Schoenrock
- B. Dechenaux
- B. Di Girolamo
- B. Di Micco
- B. E. Cox
- B. E. Lindquist
- B. Esposito
- B. G. Fulsom
- B. G. Pope
- B. Galhardo
- B. Gaur
- B. Giacobbe
- B. Gibbard
- B. Gorini
- B. H. Smart
- B. Heinemann
- B. J. Gallop
- B. J. O’Brien
- B. Jackson
- B. K. B. Chow
- B. K. Gjelsten
- B. K. Wosiek
- B. Kaplan
- B. Laforge
- B. Lemmer
- B. Lenzi
- B. Li
- B. Li
- B. Liberti
- B. Liu
- B. Lopez Paredes
- B. Lund-Jensen
- B. M. Barnett
- B. M. M. Allbrooke
- B. M. Waugh
- B. M. Wynne
- B. Malaescu
- B. Mandelli
- B. Mansoulie
- B. Martin
- B. Martin
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- B. Meirose
- B. Mindur
- B. Nicquevert
- B. Osculati
- B. P. Kerševan
- B. Penning
- B. Pinto
- B. R. Mellado Garcia
- B. S. Acharya
- B. Sarrazin
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- B. Simmons
- B. Sopko
- B. Stelzer
- B. Stugu
- B. T. King
- B. T. Winter
- B. Trocmé
- B. Vachon
- B. Walsh
- B. Weinert
- B. Yabsley
- B. Zabinski
- B. Zhou
- B. Åsman
- BC Allanach
- BP Kersevan
- C. A. Chavez Barajas
- C. A. Jung
- C. A. Lee
- C. A. Solans
- C. Alexa
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- C. Amelung
- C. Anastopoulos
- C. B. Gwilliam
- C. Bacci
- C. Becot
- C. Belanger-Champagne
- C. Bernard
- C. Bernius
- C. Bertella
- C. Bertsche
- C. Betancourt
- C. Bini
- C. Blocker
- C. Bock
- C. Bohm
- C. Bourdarios
- C. C. Chau
- C. C. Ohm
- C. Chen
- C. Clement
- C. Conta
- C. Cuthbert
- C. Da Via
- C. Dallapiccola
- C. David
- C. Debenedetti
- C. Deluca
- C. Deterre
- C. Di Donato
- C. Doglioni
- C. Escobar
- C. F. Anders
- C. Feng
- C. Ferretti
- C. Friedrich
- C. Fukunaga
- C. G. Lester
- C. G. Zhu
- C. Gabaldon
- C. Galea
- C. García
- C. Gatti
- C. Gay
- C. Gemme
- C. Giuliani
- C. Glasman
- C. Goy
- C. Guicheney
- C. Gumpert
- C. Gutschow
- C. Guyot
- C. Gwenlan
- C. Gössling
- C. Haber
- C. Helsens
- C. Hengler
- C. Hsu
- C. Isaksson
- C. Issever
- C. J. Oram
- C. J. Potter
- C. J. S. Young
- C. Jeske
- C. Kourkoumelis
- C. L. Lampen
- C. Lacasta
- C. Lapoire
- C. Leggett
- C. Leonidopoulos
- C. Leroy
- C. Limbach
- C. Luci
- C. M. Buttar
- C. M. Delitzsch
- C. M. Hawkes
- C. M. Lester
- C. Maiani
- C. Maidantchik
- C. Malone
- C. Meineck
- C. Melachrinos
- C. Meroni
- C. Meyer
- C. Meyer
- C. Mills
- C. Monini
- C. N. P. Gee
- C. Nellist
- C. O. Shimmin
- C. Oropeza Barrera
- C. P. Bee
- C. P. Buszello
- C. P. Hays
- C. P. Marino
- C. P. Ward
- C. Padilla Aranda
- C. Pahl
- C. Petridou
- C. Pizio
- C. R. Boddy
- C. R. Royon
- C. Rangel-Smith
- C. Rembser
- C. Roda
- C. Rudolph
- C. S. Pollard
- C. Sandoval
- C. Santoni
- C. Sawyer
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- C. Schillo
- C. Schmitt
- C. Schroeder
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- C. Serfon
- C. Stanescu
- C. Suhr
- C. T. Potter
- C. Taccini
- C. Troncon
- C. Tsarouchas
- C. Unverdorben
- C. W. Black
- C. W. Kalderon
- C. Wang
- C. Wang
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- D. A. Scannicchio
- D. A. Soh
- D. Amidei
- D. Barberis
- D. Benchekroun
- D. Berge
- D. Bertsche
- D. Blackburn
- D. Boscherini
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- D. Britton
- D. Bruncko
- D. Büscher
- D. C. O’Neil
- D. Caforio
- D. Calvet
- D. Cameron
- D. Casadei
- D. Cavalli
- D. Chakraborty
- D. Charfeddine
- D. Chromek-Burckhart
- D. Cinca
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- D. Côté
- D. De Pedis
- D. della Volpe
- D. Derendarz
- D. Di Valentino
- D. Dobos
- D. Duda
- D. Duschinger
- D. E. Ferreira de Lima
- D. Emeliyanov
- D. Eriksson
- D. Fassouliotis
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- D. Fournier
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- D. G. Charlton
- D. Gerbaudo
- D. Gillberg
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- D. Golubkov
- D. Goujdami
- D. Guest
- D. H. Nguyen
- D. H. Saxon
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- D. Hayden
- D. Hellmich
- D. Hirschbuehl
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- D. Hu
- D. Iliadis
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- D. Kyriazopoulos
- D. L. Adams
- D. Lacour
- D. Lellouch
- D. Levin
- D. Lissauer
- D. Liu
- D. Lopez Mateos
- D. Lynn
- D. M. Gingrich
- D. M. Rebuzzi
- D. M. Seliverstov
- D. M. Strom
- D. Macina
- D. Madaffari
- D. Malon
- D. Moreno
- D. Muenstermann
- D. O. Jamin
- D. Oliveira Damazio
- D. Orestano
- D. P. Benjamin
- D. P. C. Sankey
- D. Pallin
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- D. Pelikan
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- D. R. Quarrie
- D. R. Tovey
- D. R. Wardrope
- D. R. Yu
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- D. Rousseau
- D. S. Popovic
- D. Salek
- D. Salihagic
- D. Salvatore
- D. Sampsonidis
- D. Schaefer
- D. Schaile
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- D. Shoaleh Saadi
- D. Short
- D. Sidorov
- D. Silverstein
- D. Simon
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- D. Su
- D. T. Pignotti
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- D. Tsybychev
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- D. V. Dedovich
- D. V. Perepelitsa
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- D. Varouchas
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- DF Carvalho
- Dj. Sijacki
- DV Volkov
- E Witten
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- E. Ertel
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- E. G. Tskhadadze
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- E. N. Thompson
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- F. Ukegawa
- F. Vannucci
- F. Vazeille
- F. Veloso
- F. Vives Vaque
- F. Wang
- F. Winklmeier
- F. Zhang
- Fr. Pastore
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- Y. Takubo
- Y. Tayalati
- Y. Unno
- Y. V. Grishkevich
- Y. Wu
- Y. Yamaguchi
- Y. Yamazaki
- Y. Yang
- Y. Yasu
- Y. Zhao
- Y. Zhu
- Yu. A. Tikhonov
- Z. Barnovska
- Z. D. Greenwood
- Z. Dolezal
- Z. Gecse
- Z. H. Citron
- Z. Hajduk
- Z. Hubacek
- Z. Idrissi
- Z. J. Grout
- Z. Kohout
- Z. L. Ren
- Z. Liang
- Z. M. Karpova
- Z. Marshall
- Z. Rurikova
- Z. V. Krumshteyn
- Z. Vykydal
- Z. Weng
- Z. Yan
- Z. Zhang
- Z. Zhao
- Z. Zinonos
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2015
- Field of study
The results of a search for supersymmetry in final states containing at least one isolated lepton (electron or muon), jets and large missing transverse momentum with the ATLAS detector at the Large Hadron Collider are reported. The search is based on proton-proton collision data at a centre-of-mass energy s√=8 TeV collected in 2012, corresponding to an integrated luminosity of 20 fb−1. No significant excess above the Standard Model expectation is observed. Limits are set on supersymmetric particle masses for various supersymmetric models. Depending on the model, the search excludes gluino masses up to 1.32 TeV and squark masses up to 840 GeV. Limits are also set on the parameters of a minimal universal extra dimension model, excluding a compactification radius of 1/R c = 950 GeV for a cut-off scale times radius (ΛR c) of approximately 30
Androgen Receptor Drives Cellular Senescence
- Author
- A Prieur
- A Takahashi
- A van Bokhoven
- Alexander Yemelyanov
- B Cinar
- C Deschenes
- C Grisanzio
- CT Wu
- D Bello
- D Dankort
- DJ Rossi
- DJ Vander Griend
- Dorina Veliceasa
- DP Chopra
- EJ Tokar
- F Mehraein-Ghomi
- G Ferbeyre
- G Han
- GR Cunha
- IE Eder
- Irina Budunova
- IV Litvinov
- IV Litvinov
- IV Litvinov
- J Campisi
- J Li
- JJ Lee
- JJ Rambeaud
- JK Hess-Wilson
- JM Kokontis
- JM Vicencio
- JP Coppe
- JP Coppe
- JR Stewart
- JT Isaacs
- JW Harper
- K Itahana
- Kelly Maxwell
- Latanya Williams
- LG Korotchkina
- M Gleave
- M Verras
- MC Maiuri
- Mikhail V. Blagosklonny
- MM Khan
- MV Blagosklonny
- MV Gavrielides
- NJ Mabjeesh
- OA O'Mahony
- Olga V. Volpert
- OV Leontieva
- P Haag
- S Kasper
- S Lu
- S Macip
- S Signoretti
- SW Hayward
- T Nelius
- T Reiner
- TD Halazonetis
- V Calabro
- V Chesnokova
- VG Beaudry
- WC Burhans
- WM Keyes
- WM Keyes
- X Guo
- X Wang
- Y Xu
- Yelena Mirochnik
- Z Culig
- ZN Demidenko
- ZN Demidenko
- ZN Demidenko
- Publication venue
- Public Library of Science
- Publication date
- 05/03/2012
- Field of study
The accepted androgen receptor (AR) role is to promote proliferation and survival of prostate epithelium and thus prostate cancer progression. While growth-inhibitory, tumor-suppressive AR effects have also been documented, the underlying mechanisms are poorly understood. Here, we for the first time link AR anti-cancer action with cell senescence in vitro and in vivo. First, AR-driven senescence was p53-independent. Instead, AR induced p21, which subsequently reduced ΔN isoform of p63. Second, AR activation increased reactive oxygen species (ROS) and thereby suppressed Rb phosphorylation. Both pathways were critical for senescence as was proven by p21 and Rb knock-down and by quenching ROS with N-Acetyl cysteine and p63 silencing also mimicked AR-induced senescence. The two pathways engaged in a cross-talk, likely via PML tumor suppressor, whose localization to senescence-associated chromatin foci was increased by AR activation. All these pathways contributed to growth arrest, which resolved in senescence due to concomitant lack of p53 and high mTOR activity. This is the first demonstration of senescence response caused by a nuclear hormone receptor
Positive functioning inventory: initial validation of a 12-item self-report measure of well-being
- Author
- A Schat
- AJ Yap
- AM Wood
- AM Wood
- AM Wood
- AS Zigmond
- AT Beck
- AT Beck
- BW Smith
- CD Ryff
- CLM Keyes
- CS Carver
- D Watson
- D Watson
- E Diener
- E Diener
- E Ferguson
- G Chen
- GM Wagnild
- GR Parkinson
- J Denollet
- J Russell
- JA Gray
- JA Gray
- JA Russell
- JE Maddux
- JM Gorman
- K Konstabel
- KM DeNeve
- LA Feldman
- LJ Francis
- M Portzky
- M Rosenberg
- MEP Seligman
- MEP Seligman
- MEP Seligman
- MF Scheier
- N Endler
- N Hayes
- N Stulz
- P Ekkekakis
- PA Linley
- PF Lovibond
- R Kotov
- R Layard
- R Tennant
- RR McCrae
- RT Howell
- S Chinn
- S Cohen
- S Joseph
- S Joseph
- S Joseph
- S Joseph
- S Lyubomirsky
- T Rashid
- TM Marteau
- W Pavot
- Y Chida
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2014
- Field of study
Background: This paper describes the validation of the Positive Functioning Inventory (PFI-12). This is a 12-item self-report tool developed to assess a spectrum of functioning ranging from states of mental distress to states of well-being.
Method: Two samples (Sample 1: N = 242, mean age = 20 years. Sample 2: N = 301, mean age = 20 years) completed self-report measures of personality and social, physical and psychological functioning.
Results: Evidence is provided for internal-consistency reliability, test-retest reliability, incremental validity, and convergent and discriminant validity in relation to a number of other measures of personality, social, physical and psychological functioning.
Conclusion: The tool promises to be useful to practitioners and researchers who wish to assess positive psychological functioning
FOXM1 Induces a Global Methylation Signature That Mimics the Cancer Epigenome in Head and Neck Squamous Cell Carcinoma
- Author
- A Waseem
- Adiam W. Bahta
- Ahmad Waseem
- Andrew Yeudall
- Ayesha Nadir
- B Schilling
- C Li
- CL Yen
- CY Koo
- D Kalathas
- Deeviyaben Patel
- DR Wonsey
- E Gemenetzidis
- E Gemenetzidis
- E Georgiou
- Emilios Gemenetzidis
- ER Burton
- F Angiero
- G Castoria
- GR Bignell
- H Kitagawa
- H Uramoto
- HC Tsai
- Iain L. Hutchison
- J Ai
- J Laoukili
- JG Rheinwald
- JG Rheinwald
- K Agger
- K Dennis
- K Gaballah
- K Itahana
- K Myant
- KJ Sweeney
- LA Flanagan
- M Locke
- M Reiss
- MA Dickson
- MK Kang
- MT Teh
- MT Teh
- Muy-Teck Teh
- PS Kulkarni
- R Zhou
- Rameez Tariq
- RG Bedolla
- RK Vadlamudi
- RZ Jurkowska
- S Assou
- S Ron-Bigger
- S Timmermann
- SA Bustin
- SB Baylin
- SE Chang
- SK Li
- SS Myatt
- W Yan
- WA Palmisano
- WM Keyes
- Y Wang
- Y Yamada
- Z Wang
- Z Xie
- Z Zhong
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2012
- Field of study
The oncogene FOXM1 has been implicated in all major types of human cancer. We recently showed that aberrant FOXM1 expression causes stem cell compartment expansion resulting in the initiation of hyperplasia. We have previously shown that FOXM1 regulates HELLS, a SNF2/helicase involved in DNA methylation, implicating FOXM1 in epigenetic regulation. Here, we have demonstrated using primary normal human oral keratinocytes (NOK) that upregulation of FOXM1 suppressed the tumour suppressor gene p16INK4A (CDKN2A) through promoter hypermethylation. Knockdown of HELLS using siRNA re-activated the mRNA expression of p16INK4A and concomitant downregulation of two DNA methyltransferases DNMT1 and DNMT3B. The dose-dependent upregulation of endogenous FOXM1 (isoform B) expression during tumour progression across a panel of normal primary NOK strains (n = 8), dysplasias (n = 5) and head and neck squamous cell carcinoma (HNSCC) cell lines (n = 11) correlated positively with endogenous expressions of HELLS, BMI1, DNMT1 and DNMT3B and negatively with p16INK4A and involucrin. Bisulfite modification and methylation-specific promoter analysis using absolute quantitative PCR (MS-qPCR) showed that upregulation of FOXM1 significantly induced p16INK4A promoter hypermethylation (10-fold, P<0.05) in primary NOK cells. Using a non-bias genome-wide promoter methylation microarray profiling method, we revealed that aberrant FOXM1 expression in primary NOK induced a global hypomethylation pattern similar to that found in an HNSCC (SCC15) cell line. Following validation experiments using absolute qPCR, we have identified a set of differentially methylated genes, found to be inversely correlated with in vivo mRNA expression levels of clinical HNSCC tumour biopsy samples. This study provided the first evidence, using primary normal human cells and tumour tissues, that aberrant upregulation of FOXM1 orchestrated a DNA methylation signature that mimics the cancer methylome landscape, from which we have identified a unique FOXM1-induced epigenetic signature which may have clinical translational potentials as biomarkers for early cancer screening, diagnostic and/or therapeutic interventions
Complexity Theory for a New Managerial Paradigm: A Research Framework
- Author
- A Bertoncelj
- A Carroll
- A Kieser
- AL Rice
- AM Grant
- AM Kaplan
- B Christopher Houghton
- C Antonelli
- C Argyris
- C Gresov
- C O’Dell
- C-L Yang
- C-L Yang
- CA Ramus
- CJ Bertot
- CW Frederick
- D Lynch
- D Pearce
- D Walters
- DC Mikulecky
- E Laszlo
- E Villalba
- EB Barbier
- EH Schein
- F Boons
- F Firat
- F Montalto
- G Carrion-Cepeda
- G Dominici
- G Dominici
- G Dominici
- G Perry
- G Ross
- GC Avery
- GC Avery
- GM Golinelli
- GR Teisman
- H Deresky
- H Ny
- I Brinkley
- I Prigogine
- IM Winn
- J Elkington
- J Pirsch
- J Stiglitz
- J Valacich
- JAF Stoner
- JAG Kleef van
- JR Boatright
- JR Schermerhorn
- JW Meyer
- KB Usrey
- KD Bailey
- KE Boulding
- KT Jackson
- L Bertalanffy von
- L Bertalanffy von
- LE Sekerka
- M Armstrong
- M Cohen
- M Csikszentmihalyi
- M Easterby-Smith
- M Kuula
- M Mulej
- M Uhl-Bien
- ME Porter
- MJ Hatch
- MS Aßländer
- MS Schwartz
- N Luhmann
- N Luhmann
- N Luhmann
- N Wiener
- N Wiener
- P Burke
- PJ Elliott Dupuy
- PS Chan
- R Espejo
- R George De
- R Keyes
- R Tulder van
- R Tulder van
- RD Stacey
- S Beer
- SC Certo
- SR Kaplan
- SY Auyang
- T Panayotou
- TJ Tetenbaum
- TM Devinney
- U Merry
- U Pagano
- V Potocan
- V Roblek
- V Valentinov
- VA Zelizer
- WC Autry
- WH Staehle
- World Business Council for Sustainable Development
- Z Bauman
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2015
- Field of study
In this work, we supply a theoretical framework of how organizations
can embed complexity management and sustainable development into their policies
and actions. The proposed framework may lead to a new management paradigm,
attempting to link the main concepts of complexity theory, change management,
knowledge management, sustainable development, and cybernetics. We highlight
how the processes of organizational change have occurred as a result of the move to
adapt to the changes in the various global and international business environments
and how this transformation has led to the shift toward the present innovation
economy. We also point how organizational change needs to deal with sustainability,
so that the change may be consistent with present needs, without compromising
the future
Measurement of VH, H → b b ¯ production as a function of the vector-boson transverse momentum in 13 TeV pp collisions with the ATLAS detector
- Author
- Aaboud M
- Aad G
- Abbott B
- Abbott DC
- Abdinov O
- Abhayasinghe DK
- Abidi SH
- AbouZeid OS
- Abraham NL
- Abramowicz H
- Abreu H
- Abud AA
- Abulaiti Y
- Acharya BS
- Adachi S
- Adam L
- Adamczyk L
- Adamek L
- Adelman J
- Adersberger M
- Adiguzel A
- Adorni S
- Adye T
- Affolder AA
- Afik Y
- Agapopoulou C
- Agaras MN
- Aggarwal A
- Agheorghiesei C
- Aguilar-Saavedra JA
- Ahmadov F
- Aielli G
- Akatsuka S
- Akesson TPA
- Akilli E
- Akimov AV
- Al Khoury K
- Alberghi GL
- Alberich LC
- Albert J
- Alconada Verzini MJ
- Alderweireldt S
- Aleksa M
- Aleksandrov IN
- Alexa C
- Alexandre D
- Alexopoulos T
- Alfonsi A
- Alhroob M
- Ali B
- Alimonti G
- Alison J
- Alkire SP
- Allaire C
- Allbrooke BMM
- Allen BW
- Allport PP
- Aloisio A
- Alonso A
- Alonso F
- Alpigiani C
- Alshehri AA
- Alstaty MI
- Alvarez Estevez M
- Alvarez Piqueras D
- Alviggi MG
- Amaral Coutinho Y
- Ambler A
- Ambroz L
- Amelung C
- Amidei D
- Amor Dos Santos SP
- Amoroso S
- Amrouche CS
- An F
- Anastopoulos C
- Andari N
- Andeen T
- Anders CF
- Anders JK
- Andreazza A
- Andrei V
- Anelli CR
- Angelidakis S
- Angelozzi I
- Angerami A
- Anisenkov AV
- Annovi A
- Antel C
- Anthony MT
- Antonelli M
- Antrim DJA
- Anulli F
- Aoki M
- Aparisi Pozo JA
- Arabidze G
- Araque JP
- Araujo Ferraz V
- Araujo Pereira R
- Araya ST
- Arce ATH
- Arduh FA
- Arguin J-F
- Argyropoulos S
- Arling J-H
- Armadans RC
- Armbruster AJ
- Armitage LJ
- Armstrong A
- Arnaez O
- Arnold H
- Artamonov A
- Artoni G
- Artz S
- Asai S
- Asbah N
- Asimakopoulou EM
- Asquith L
- Assamagan K
- Astalos R
- Astigarraga MEP
- Atkin RJ
- Atkinson M
- Atlay NB
- Atmani H
- Augsten K
- Avolio G
- Avramidou R
- Ayoub MK
- Azoulay AM
- Azuelos G
- Baas AE
- Baca MJ
- Bachacou H
- Bachas K
- Backes M
- Backman F
- Bagnaia P
- Bahmani M
- Bahrasemani H
- Bailey AJ
- Bailey VR
- Baines JT
- Bajic M
- Bakalis C
- Baker OK
- Bakker PJ
- Balaji S
- Baldin EM
- Balek P
- Balli F
- Balunas WK
- Balz J
- Banas E
- Bandyopadhyay A
- Banerjee S
- Bannoura AAE
- Barajas CAC
- Barak L
- Barbe WM
- Barberio EL
- Barberis D
- Barbero M
- Barillari T
- Barisits M-S
- Barkeloo J
- Barklow T
- Barnea R
- Barnes SL
- Barnett BM
- Barnett RM
- Barnovska-Blenessy Z
- Baroncelli A
- Barone G
- Barr AJ
- Barranco Navarro L
- Barreiro F
- Bartoldus R
- Bartolini G
- Barton AE
- Bartos P
- Basalaev A
- Bassalat A
- Bates RL
- Batista SJ
- Batlamous S
- Batley JR
- Batool B
- Battaglia M
- Bauce M
- Bauer F
- Bauer KT
- Bawa HS
- Beacham JB
- Beau T
- Beauchemin PH
- Bechtle P
- Beck HC
- Beck HP
- Becker K
- Becker M
- Becot C
- Beddall A
- Beddall AJ
- Bednyakov VA
- Bedognetti M
- Bee CP
- Beermann TA
- Begalli M
- Begel M
- Behera A
- Behr JK
- Beisiegel F
- Bell AS
- Bella G
- Bella LA
- Bellagamba L
- Bellerive A
- Bellos P
- Beloborodov K
- Belotskiy K
- Belyaev NL
- Benary O
- Benchekroun D
- Benekos N
- Benhammou Y
- Benjamin DP
- Benoit M
- Bensinger JR
- Bentvelsen S
- Beresford L
- Beretta M
- Berge D
- Berger N
- Bergmann B
- Bergsten LJ
- Beringer J
- Berlendis S
- Berlingen JM
- Bernard NR
- Bernardi G
- Bernius C
- Bernlochner FU
- Berry T
- Berta P
- Bertella C
- Bertoli G
- Bertram IA
- Besjes GJ
- Besson N
- Bethani A
- Bethke S
- Betti A
- Bevan AJ
- Beyer J
- Bi R
- Bianchi RM
- Biebel O
- Biedermann D
- Bielski R
- Bierwagen K
- Biesuz NV
- Biglietti M
- Billoud TRV
- Bindi M
- Bingul A
- Bini C
- Biondi S
- Birman M
- Bisanz T
- Biswal JP
- Bitadze A
- Bittrich C
- Bjergaard DM
- Black JE
- Black KM
- Blazek T
- Bloch I
- Blocker C
- Blue A
- Blumenschein U
- Bobbink GJ
- Bobrovnikov VS
- Bocchetta SS
- Bocci A
- Boeriu OEV
- Boerner D
- Bogavac D
- Bogdanchikov AG
- Bohm C
- Boisvert V
- Bokan P
- Bold T
- Boldyrev AS
- Bolz AE
- Bomben M
- Bona M
- Bonilla JS
- Boonekamp M
- Borecka-Bielska HM
- Borisov A
- Borissov G
- Bortfeldt J
- Bortoletto D
- Bortolotto V
- Boscherini D
- Bosman M
- Bostanabad MG
- Bouaouda K
- Boudreau J
- Bouhova-Thacker EV
- Boumediene D
- Bourdarios CA
- Boutle SK
- Boveia A
- Boyd J
- Boye D
- Boyko IR
- Bozson AJ
- Bracinik J
- Brahimi N
- Brandt G
- Brandt O
- Braren F
- Bratzler U
- Brau B
- Brau JE
- Brendlinger K
- Brenner L
- Brenner R
- Bressler S
- Bret MC
- Brickwedde B
- Briglin DL
- Britton D
- Britzger D
- Brock I
- Brock R
- Brooijmans G
- Brooks T
- Brooks WK
- Brost E
- Broughton JH
- Bruncko D
- Bruni A
- Bruni G
- Bruni LS
- Bruno S
- Brunt BH
- Bruschi M
- Bruscino N
- Bryant P
- Bryngemark L
- Buanes T
- Buat Q
- Buchholz P
- Buckley AG
- Budagov IA
- Buehrer F
- Buescher V
- Bugge MK
- Bulekov O
- Burch TJ
- Burdin S
- Burgard CD
- Burger AM
- Burghgrave B
- Burka K
- Burr JTP
- Buschmann E
- Bussey PJ
- Butler JM
- Buttar CM
- Butterworth JM
- Butti P
- Buttinger W
- Buzatu A
- Buzykaev AR
- Bylund OB
- Cabras G
- Cabrera Urban S
- Caforio D
- Cai H
- Cairo VMM
- Cakir O
- Calace N
- Calafiura P
- Calandri A
- Calderini G
- Calfayan P
- Callea G
- Caloba LP
- Calvente Lopez S
- Calvet D
- Calvet S
- Calvet TP
- Calvetti M
- Camarda S
- Camarero Munoz D
- Camarri P
- Cameron D
- Camincher C
- Campana S
- Campanelli M
- Camplani A
- Campoverde A
- Canale V
- Canesse A
- Cantero J
- Cao T
- Cao Y
- Capua M
- Cardarelli R
- Cardillo FC
- Carli I
- Carli T
- Carlino G
- Carlson BT
- Carminati L
- Carney RMD
- Caron S
- Carquin E
- Carra S
- Carter JWS
- Casado MP
- Casha AF
- Casper DW
- Castelijn R
- Castillo Gimenez V
- Castillo FL
- Castillo LRF
- Castro NF
- Catinaccio A
- Catmore JR
- Cattai A
- Caudron J
- Cavaliere V
- Cavallaro E
- Cavalli D
- Cavalli-Sforza M
- Cavasinni V
- Celebi E
- Ceradini F
- Cerqueira AS
- Cerri A
- Cerrito L
- Cerutti F
- Cervelli A
- Cetin SA
- Chafaq A
- Chakraborty D
- Chan SK
- Chan WS
- Chan WY
- Chapman JD
- Chargeishvili B
- Charlton DG
- Chau CC
- Che S
- Chegwidden A
- Chekanov S
- Chekulaev SV
- Chelkov GA
- Chelstowska MA
- Chen B
- Chen C
- Chen CH
- Chen H
- Chen J
- Chen J
- Chen S
- Chen SJ
- Chen X
- Chen Y
- Chen Y-H
- Cheng HC
- Cheng HJ
- Cheplakov A
- Cheremushkina E
- Cheu E
- Cheung K
- Chevalerias TJA
- Chevalier L
- Chiarella V
- Chiarelli G
- Chiodini G
- Chisholm AS
- Chitan A
- Chiu I
- Chiu YH
- Chizhov MV
- Choi K
- Chomont AR
- Chouridou S
- Chow YS
- Chu MC
- Chudoba J
- Chuinard AJ
- Chwastowski JJ
- Chytka L
- Cinca D
- Cindro V
- Cioara IA
- Ciocio A
- Cirotto F
- Citron ZH
- Citterio M
- Ciungu BM
- Clark A
- Clark MR
- Clark PJ
- Clement C
- Coadou Y
- Cobal M
- Coccaro A
- Cochran J
- Cohen H
- Coimbra AEC
- Colasurdo L
- Cole B
- Colijn AP
- collaboration ATLAS
- Collot J
- Conde Muino P
- Coniavitis E
- Connell SH
- Connelly IA
- Constantinescu S
- Conventi F
- Cooper-Sarkar AM
- Corga KDV
- Cormier F
- Cormier KJR
- Cornell SD
- Corpe LD
- Corradi M
- Correia AMH
- Corrigan EE
- Corriveau F
- Cortes-Gonzalez A
- Costa MJ
- Costanza F
- Costanzo D
- Cowan G
- Cowley JW
- Crane J
- Cranmer K
- Crawley SJ
- Creager RA
- Crepe-Renaudin S
- Crescioli F
- Cristinziani M
- Croft V
- Crosetti G
- Cueto A
- Cukierman AR
- Czekierda S
- Czodrowski P
- D'amen G
- D'Auria S
- D'Eramo L
- D'onofrio A
- D'Onofrio M
- da Costa JBG
- Da Fonseca Pinto JV
- Da Via C
- Dabrowski W
- Dado T
- Dahbi S
- Dai T
- Dallapiccola C
- Dam M
- Damazio DO
- Damp J
- Dandoy JR
- Daneri MF
- Dang NP
- Dann ND
- Danninger M
- Dao V
- Darbo G
- Dartsi O
- Dattagupta A
- Daubney T
- Davey W
- David C
- Davidek T
- Davis DR
- Dawe E
- Dawson I
- De Asmundis R
- De Benedetti A
- De Beurs M
- De Bruin PHS
- De Castro S
- De Cecco S
- De Groot N
- de Jong P
- De la Torre H
- de Lima DEF
- De Lima RT
- De Maria A
- De Pedis D
- De Regie JBDV
- de Renstrom PAB
- De Salvo A
- De Sanctis U
- De Santis M
- De Santo A
- De Sousa MJDCS
- De K
- Debenedetti C
- Dedovich DV
- Deiana AM
- Del Gaudio M
- Del Peso J
- Delabat Diaz Y
- Delgove D
- Deliot F
- Delitzsch CM
- Dell'Acqua A
- Dell'Asta L
- Della Pietra M
- Della Volpe D
- Delmastro M
- Delporte C
- Delsart PA
- DeMarco DA
- Demers S
- Demichev M
- Demontigny G
- Denisov SP
- Denysiuk D
- Derendarz D
- Derkaoui JE
- Derue F
- Dervan P
- Desch K
- Deterre C
- Dette K
- Devesa MR
- Deviveiros PO
- Dewhurst A
- Dhaliwal S
- Di Bello FA
- Di Ciaccio A
- Di Ciaccio L
- Di Clemente WK
- Di Donato C
- Di Girolamo A
- Di Gregorio G
- Di Micco B
- Di Nardo R
- Di Petrillo KF
- Di Sipio R
- Di Valentino D
- Diaconu C
- Dias Do Vale T
- Dias FA
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- Zaripovas DR
- Zeissner SV
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- Zeng JC
- Zenin O
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- Zhang Y
- Zhang Z
- Zhang Z
- Zhao P
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- Zhao Z
- Zhemchugov A
- Zheng Z
- Zhong D
- Zhou B
- Zhou C
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- Zhou MS
- Zhou N
- Zhou Y
- Zhu CG
- Zhu H
- Zhu HL
- Zhu J
- Zhu Y
- Zhuang X
- Zhukov K
- Zhulanov V
- Zieminska D
- Zimine NI
- Zimmermann S
- Zinonos Z
- Ziolkowski M
- Zivkovic L
- Zobernig G
- Zoccoli A
- Zoch K
- Zorbas TG
- Zou R
- Zu Theenhausen HM
- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2019
- Field of study
Cross-sections of associated production of a Higgs boson decaying into bottom-quark pairs and an electroweak gauge boson, W or Z, decaying into leptons are measured as a function of the gauge boson transverse momentum. The measurements are performed in kinematic fiducial volumes defined in the `simplified template cross-section' framework. The results are obtained using 79.8 fb-1 of proton-proton collisions recorded by the ATLAS detector at the Large Hadron Collider at a centre-of-mass energy of 13 TeV. All measurements are found to be in agreement with the Standard Model predictions, and limits are set on the parameters of an effective Lagrangian sensitive to modifications of the Higgs boson couplings to the electroweak gauge bosons
Search for High-Mass Resonances Decaying to τν in pp Collisions at √s=13 TeV with the ATLAS Detector
- Author
- Aaboud M
- Aad G
- Abbott B
- Abdinov O
- Abeloos B
- Abidi SH
- AbouZeid OS
- Abraham NL
- Abramowicz H
- Abreu H
- Abulaiti Y
- Acharya BS
- Adachi S
- Adamczyk L
- Adelman J
- Adersberger M
- Adye T
- Affolder AA
- Afik Y
- Agheorghiesei C
- Aguilar-Saavedra JA
- Ahlen SP
- Ahmadov F
- Aielli G
- Akatsuka S
- Akesson TPA
- Akilli E
- Akimov AV
- Alberghi GL
- Albert J
- Albicocco P
- Alconada Verzini MJ
- Alderweireldt S
- Aleksa M
- Aleksandrov IN
- Alexa C
- Alexander G
- Alexopoulos T
- Alhroob M
- Ali B
- Aliev M
- Alimonti G
- Alison J
- Alkire SP
- Allaire C
- Allbrooke BMM
- Allen BW
- Allport PP
- Aloisio A
- Alonso A
- Alonso F
- Alpigiani C
- Alshehri AA
- Alstaty MI
- Alvarez Gonzalez B
- Alvarez Piqueras D
- Alviggi MG
- Amadio BT
- Amaral Coutinho Y
- Ambroz L
- Amelung C
- Amidei D
- Amor Dos Santos SP
- Amoroso S
- Amrouche CS
- Anastopoulos C
- Ancu LS
- Andari N
- Andeen T
- Anders CF
- Anders JK
- Anderson KJ
- Andreazza A
- Andrei V
- Angelidakis S
- Angelozzi I
- Angerami A
- Anisenkov AV
- Annovi A
- Antel C
- Anthony MT
- Antonelli M
- Antrim DJ
- Anulli F
- Aoki M
- Arabidze G
- Arai Y
- Araque JP
- Araujo Ferraz V
- Araujo Pereira R
- Araya S Tapia
- Arce ATH
- Ardell RE
- Arduh FA
- Arguin J-F
- Argyropoulos S
- Armadans R Caminal
- Armbruster AJ
- Armitage LJ
- Arnaez O
- Arnold H
- Arratia M
- Arslan O
- Artamonov A
- Artoni G
- Artz S
- Asai S
- Asbah N
- Ashkenazi A
- Asimakopoulou EM
- Asquith L
- Assamagan K
- Astalos R
- Astigarraga ME Pozo
- Atkin RJ
- Atkinson M
- Atlay NB
- Augsten K
- Avolio G
- Avramidou R
- Axen B
- Ayoub MK
- Azuelos G
- Baas AE
- Baca MJ
- Bachacou H
- Bachas K
- Backes M
- Bagnaia P
- Bahmani M
- Bahrasemani H
- Baines JT
- Bajic M
- Baker OK
- Bakker PJ
- Baldin EM
- Balek P
- Balli F
- Balunas WK
- Banas E
- Bandyopadhyay A
- Banerjee Sw
- Bannoura AAE
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- Zorbas TG
- Zou R
- Zu Theenhausen H Meyer
- zur Nedden M
- Zwalinski L
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2018
- Field of study
A search for high-mass resonances decaying to τν using proton-proton collisions at √s=13 TeV produced by the Large Hadron Collider is presented. Only τ-lepton decays with hadrons in the final state are considered. The data were recorded with the ATLAS detector and correspond to an integrated luminosity of 36.1 fb−1. No statistically significant excess above the standard model expectation is observed; model-independent upper limits are set on the visible τν production cross section. Heavy W′ bosons with masses less than 3.7 TeV in the sequential standard model and masses less than 2.2–3.8 TeV depending on the coupling in the nonuniversal G(221) model are excluded at the 95% credibility level
Search for the direct production of charginos and neutralinos in final states with tau leptons in √s=13 TeV collisions with the ATLAS detector
- Author
- Aaboud M
- Aad G
- Abbott B
- Abdinov O
- Abeloos B
- Abidi SH
- AbouZeid OS
- Abraham NL
- Abramowicz H
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- Aleksandrov IN
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2017
- Field of study
A search for the direct production of charginos and neutralinos in final states with at least two hadronically decaying tau leptons is presented. The analysis uses a dataset of pp collisions corresponding to an integrated luminosity of 36.1 fb−1, recorded with the ATLAS detector at the Large Hadron Collider at a centre-of-mass energy of 13TeV.Nosignificant deviation from the expected Standard Model background is observed. Limits are derived in scenarios of ˜χ+1 ˜χ−1 pair production and of ˜χ±1 ˜χ02 and ˜χ+1 ˜χ−1 production in simplified models where the neutralinos and charginos decay solely via intermediate left-handed staus and tau sneutrinos, and the mass of the ˜ τL state is set to be halfway between the masses of the ˜χ±1 and the ˜χ01. Chargino masses up to 630 GeV are excluded at 95% confidence level in the scenario of direct production of ˜χ+1 ˜χ−1 for a massless ˜χ01. Common ˜χ±1 and ˜χ02 masses up to 760 GeV are excluded in the case of production of ˜χ±1 ˜χ02 and ˜χ+1 ˜χ−1 assuming a massless ˜χ01. Exclusion limits for additional benchmark scenarios with large and small mass-splitting between the ˜χ±1 and the ˜χ01 are also studied by varying the ˜ τL mass between the masses of the ˜χ±1 and the ˜χ01
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