SDVADC: Secure Deduplication and Virtual Auditing of Data in Cloud

Over the last few years, deploying data to cloud service for repository is an appealing passion that avoids efforts on significant information sustenance and administration. In distributed repository utilities, deduplication technique is often exploited to minimize the capacity and bandwidth necesseties of amenities by erasing repetitive data and caching only a solitary duplicate of them. Proof-of-Ownership mechanisms authorize any possessor of the identical information to approve to the distributed repository server that he possess the information in a dynamic way. In repository utilities with enormous information, the repository servers may intend to minimize the capacity of cached information, and the customers may want to examine the integrity of their information with a reasonable cost. We propose Secure Deduplication and Virtual Auditing of Data in Cloud (SDVADC) mechanism that realizes integrity auditing and

Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2015: A systematic analysis for the Global Burden of Disease Study 2015

Background: The Global Burden of Diseases, Injuries, and Risk Factors Study 2015 provides an up-to-date synthesis of the evidence for risk factor exposure and the attributable burden of disease. By providing national and subnational assessments spanning the past 25 years, this study can inform debates on the importance of addressing risks in context. Methods: We used the comparative risk assessment framework developed for previous iterations of the Global Burden of Disease Study to estimate attributable deaths, disability-adjusted life-years (DALYs), and trends in exposure by age group, sex, year, and geography for 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks from 1990 to 2015. This study included 388 risk-outcome pairs that met World Cancer Research Fund-defined criteria for convincing or probable evidence. We extracted relative risk and exposure estimates from randomised controlled trials, cohorts, pooled cohorts, household surveys, census data, satellite data, and other sources. We used statistical models to pool data, adjust for bias, and incorporate covariates. We developed a metric that allows comparisons of exposure across risk factors—the summary exposure value. Using the counterfactual scenario of theoretical minimum risk level, we estimated the portion of deaths and DALYs that could be attributed to a given risk. We decomposed trends in attributable burden into contributions from population growth, population age structure, risk exposure, and risk-deleted cause-specific DALY rates. We characterised risk exposure in relation to a Socio-demographic Index (SDI). Findings: Between 1990 and 2015, global exposure to unsafe sanitation, household air pollution, childhood underweight, childhood stunting, and smoking each decreased by more than 25%. Global exposure for several occupational risks, high body-mass index (BMI), and drug use increased by more than 25% over the same period. All risks jointly evaluated in 2015 accounted for 57·8% (95% CI 56·6–58·8) of global deaths and 41·2% (39·8–42·8) of DALYs. In 2015, the ten largest contributors to global DALYs among Level 3 risks were high systolic blood pressure (211·8 million [192·7 million to 231·1 million] global DALYs), smoking (148·6 million [134·2 million to 163·1 million]), high fasting plasma glucose (143·1 million [125·1 million to 163·5 million]), high BMI (120·1 million [83·8 million to 158·4 million]), childhood undernutrition (113·3 million [103·9 million to 123·4 million]), ambient particulate matter (103·1 million [90·8 million to 115·1 million]), high total cholesterol (88·7 million [74·6 million to 105·7 million]), household air pollution (85·6 million [66·7 million to 106·1 million]), alcohol use (85·0 million [77·2 million to 93·0 million]), and diets high in sodium (83·0 million [49·3 million to 127·5 million]). From 1990 to 2015, attributable DALYs declined for micronutrient deficiencies, childhood undernutrition, unsafe sanitation and water, and household air pollution; reductions in risk-deleted DALY rates rather than reductions in exposure drove these declines. Rising exposure contributed to notable increases in attributable DALYs from high BMI, high fasting plasma glucose, occupational carcinogens, and drug use. Environmental risks and childhood undernutrition declined steadily with SDI; low physical activity, high BMI, and high fasting plasma glucose increased with SDI. In 119 countries, metabolic risks, such as high BMI and fasting plasma glucose, contributed the most attributable DALYs in 2015. Regionally, smoking still ranked among the leading five risk factors for attributable DALYs in 109 countries; childhood underweight and unsafe sex remained primary drivers of early death and disability in much of sub-Saharan Africa. Interpretation: Declines in some key environmental risks have contributed to declines in critical infectious diseases. Some risks appear to be invariant to SDI. Increasing risks, including high BMI, high fasting plasma glucose, drug use, and some occupational exposures, contribute to rising burden from some conditions, but also provide opportunities for intervention. Some highly preventable risks, such as smoking, remain major causes of attributable DALYs, even as exposure is declining. Public policy makers need to pay attention to the risks that are increasingly major contributors to global burden. Funding: Bill & Melinda Gates Foundation

Global, regional, and national age-sex-specific mortality and life expectancy, 1950–2017: a systematic analysis for the Global Burden of Disease Study 2017

BACKGROUND: Assessments of age-specific mortality and life expectancy have been done by the UN Population Division, Department of Economics and Social Affairs (UNPOP), the United States Census Bureau, WHO, and as part of previous iterations of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD). Previous iterations of the GBD used population estimates from UNPOP, which were not derived in a way that was internally consistent with the estimates of the numbers of deaths in the GBD. The present iteration of the GBD, GBD 2017, improves on previous assessments and provides timely estimates of the mortality experience of populations globally. METHODS: The GBD uses all available data to produce estimates of mortality rates between 1950 and 2017 for 23 age groups, both sexes, and 918 locations, including 195 countries and territories and subnational locations for 16 countries. Data used include vital registration systems, sample registration systems, household surveys (complete birth histories, summary birth histories, sibling histories), censuses (summary birth histories, household deaths), and Demographic Surveillance Sites. In total, this analysis used 8259 data sources. Estimates of the probability of death between birth and the age of 5 years and between ages 15 and 60 years are generated and then input into a model life table system to produce complete life tables for all locations and years. Fatal discontinuities and mortality due to HIV/AIDS are analysed separately and then incorporated into the estimation. We analyse the relationship between age-specific mortality and development status using the Socio-demographic Index, a composite measure based on fertility under the age of 25 years, education, and income. There are four main methodological improvements in GBD 2017 compared with GBD 2016: 622 additional data sources have been incorporated; new estimates of population, generated by the GBD study, are used; statistical methods used in different components of the analysis have been further standardised and improved; and the analysis has been extended backwards in time by two decades to start in 1950. FINDINGS: Globally, 18·7% (95% uncertainty interval 18·4–19·0) of deaths were registered in 1950 and that proportion has been steadily increasing since, with 58·8% (58·2–59·3) of all deaths being registered in 2015. At the global level, between 1950 and 2017, life expectancy increased from 48·1 years (46·5–49·6) to 70·5 years (70·1–70·8) for men and from 52·9 years (51·7–54·0) to 75·6 years (75·3–75·9) for women. Despite this overall progress, there remains substantial variation in life expectancy at birth in 2017, which ranges from 49·1 years (46·5–51·7) for men in the Central African Republic to 87·6 years (86·9–88·1) among women in Singapore. The greatest progress across age groups was for children younger than 5 years; under-5 mortality dropped from 216·0 deaths (196·3–238·1) per 1000 livebirths in 1950 to 38·9 deaths (35·6–42·83) per 1000 livebirths in 2017, with huge reductions across countries. Nevertheless, there were still 5·4 million (5·2–5·6) deaths among children younger than 5 years in the world in 2017. Progress has been less pronounced and more variable for adults, especially for adult males, who had stagnant or increasing mortality rates in several countries. The gap between male and female life expectancy between 1950 and 2017, while relatively stable at the global level, shows distinctive patterns across super-regions and has consistently been the largest in central Europe, eastern Europe, and central Asia, and smallest in south Asia. Performance was also variable across countries and time in observed mortality rates compared with those expected on the basis of development. INTERPRETATION: This analysis of age-sex-specific mortality shows that there are remarkably complex patterns in population mortality across countries. The findings of this study highlight global successes, such as the large decline in under-5 mortality, which reflects significant local, national, and global commitment and investment over several decades. However, they also bring attention to mortality patterns that are a cause for concern, particularly among adult men and, to a lesser extent, women, whose mortality rates have stagnated in many countries over the time period of this study, and in some cases are increasing

SDCS: Secure data centric sensor networks with multi-query optimization

In large-scale Wireless Sensor Networks (WSNs) the amount of data gathered require energy efficient data dissemination and data retrieval techniques. Data Centric Sensor (DCS) networks is a better approach in which the sensed data are sent to a sensor node whose name is associated with sensed data. Due to unattended nature of Wireless Sensor Networks, these sensor nodes are susceptible to different types of attacks. In this paper we propose a Secure Data Centric Sensor (SDCS) Networks that includes security and privacy support to DCS networks. In addition, we propose a multi-query optimization technique that aggregates similar queries and reduces the number of messages. Simulation and experimental results show that our work provides a secure data centric sensor network based on cryptographic keys and reduces the message overhead and incurs a minimum communication cost compared to previous works. © 2013 IEEE

Automatic Extraction of Facets for User Queries [AEFUQ]

A user query facet is a collection of items that summarizes the content covered by a query. In general, the most significant information of a user query is present in the top retrieved document that are in the form of lists. In this work, we propose a framework Automatic Extraction of Facets for User Queries [AEFUQ] that extract the user query facets automatically by grouping the list based on three categories namely HTML tags, free text patterns and repeat regions. Grouping of the list is based on domain sites present in the list. We observe that some of the lists are not relevant for extracting the facets. In order to prune these lists, the importance of each item in the lists that are present in the group G is evaluated and Cosine Similarity (CS) between two items is calculated. Further, based on CS score obtained, High Quality Clustering (HQC) algorithm is proposed to cluster the items that has the most number of point in each

SARRC: Secure Auditing and Re-signing of Revoked Customer Chunks by Cloud Using Regression Method

The demand of deploying information has enormously increased within the last decade. Numerous distributed computing service suppliers have emerged (for eg., Microsoft Azure, Dropbox) in order to satisfy the requirements for information repository and high performance computation. The customers using the cloud repository services can conveniently arrange as a cluster and distribute information among themselves. Information proprietor computes the signatures for every chunk and deploys in the distributed server in order to allow the public verifier to perform public integrity verification on the information stored on the cloud server. In Panda scheme [1], by using the proxy re-signatures, Cloud Service Provider (CSP) verifies and re-signs the revoked customer chunks in favor of the existing customers. The malicious CSP might use the Resign key deliberately to transform the signature of one customer to another

Copper interactions with DNA of chromatin and its role in neurodegenerative disorders

In this study, we have demonstrated the conformational changes to DNA induced by abnormal interactions of copper using circular dichroism, in combination with UV-absorbance and fluorescence spectroscopy. Results confirm that binding of copper to bases of DNA in chromatin is concentration dependent. Binding efficiency of Cu2+ ions to DNA is increased in proportion to the degree of unwinding of the double helix induced by denaturation. Altered B-DNA conformation will alter the integrity of DNA which may affect the normal process of DNA replication and transcription. Copper induced DNA damage in the brain may cause neurotoxicity and the neuronal cell death and is implicated in Alzheimer's disease and other neurological disorders. Keywords: Human brain, Chromatin, DNA, Copper, Neurodegenerative disorder

Efficient Auditing for Outsourced Database with Token Enforced Cloud Storage

Database outsourcing is one of the important utilities in cloud computing in which the Information Proprietor (IP) transfers the database administration to the Cloud Service Provider (CSP) in order to minimize the administration cost and preservation expenses of the database. Inspite of its immense profit, it undergoes few security issues such as privacy of deployed database and provability of search results. In the recent past, few of the studies have been carried out on provability of search results of Outsourced Database (ODB) that affords correctness and completeness of search results. But in the existing schemes, since there is flow of data between the Information Proprietor and the clients frequently, huge communication cost prevails at the Information Proprietor side. To address this challenge, in this paper we propose Efficient Auditing for Outsourced Database with Token Enforced Cloud Storage (EAODBT). The

SRCBT: Secure Regeneration of Corrupted Blocks by TPA in Cloud

To conserve the deployed information in cloud repository contrary to adulterations, including fault toleration to cloud repository together with information integrity verification and failure restoration becomes important. Belatedly, reconstructing codes acquire recognition because of their reduced reparation bandwidth while ensuring fault toleration. Prevailing distant auditing schemes for reconstructing-coded information authorizes an intermediary to reconstruct authenticators and information blocks on the suspended servers in the course of the reparation process. To address this issue, we propose Secure Regeneration of Corrupted Blocks by TPA in Cloud (SRCBT). We eliminate the semi-trusted proxy and allow the TPA to reconstruct authenticators and information chunks on the suspended servers in the course of the reparation process. Thus, our mechanism can totally relinquish information proprietors from online