Efecto de la temperatura en poblaciones de Dendroctonus frontalis Zimmerman y Dendroctonus mexicanus Hopkins (Coleoptera: Curculionidae: Scolytinae) bajo un escenario de cambio climático en la Sierra Gorda queretana

In Mexico, about 17,900 ha of coniferous forests were affected in 2016 because of outbreaks of bark beetles. The increase in temperatures caused by climate change has been observed that directly affect pine forests and favors the development of insect pests. Altitude gradients generate temperature gradients, which are good study models in a context of climate changes. The aim of this study was to determine the effect of temperature on the abundance of Dendroctonus frontalis and Dendrocotonus mexicanus throughout its altitudinal distribution range, as well as determine a possible future change in abundance by 2030 in a climate change scenario. The results showed the highest abundance of D. frontalis and D. mexicanus at altitudes between 1,589 to 1,716 masl, where temperatures were higher than 16 °C; however at altitudes upper than 2,393 masl, the abundance of both species were lower, corresponding to temperatures below 13 °C. The A1B climate change scenario predicted that the temperature will increase 3.9 °C from 2015-2016 to 2030.En México fueron afectadas alrededor de 17,900 ha de bosques de coníferas en 2016 a causa de los brotes de insectos descortezadores. Se ha observado que el aumento en las temperaturas ocasionadas por el cambio climático afecta directamente a los bosques de pino y favorece el desarrollo de insectos plaga. Los gradientes altitudinales generan gradientes climáticos, por lo cual, son buenos modelos de estudio en un contexto de cambio climático. El objetivo del estudio fue determinar el efecto de la temperatura y la abundancia de Dendroctonus frontalis y Dendroctonus mexicanus a lo largo del rango de distribución altitudinal, así como determinar un posible cambio en la abundancia para 2030 bajo un escenario de cambio climático. Los resultados evidenciaron que la mayor abundancia de D. frontalis y D. mexicanus se encuentra en altitudes entre los 1,589 y 1,716 msnm, donde ocurren temperaturas superiores a 16 °C, y en altitudes mayores a los 2,393 msnm la abundancia de ambas especies es menor, correspondiendo a temperaturas menores a 13°C. El escenario A1B de cambio climático predice que la temperatura aumentará del 2015-2016 al año 2030 3.9 °C en promedio

Linking ecological niche models and common garden experiments to predict phenotypic differentiation in stressful environments: Assessing the adaptive value of marginal populations in an alpine plant

Environmental variation within a species’ range can create contrasting selective pressures, leading to divergent selection and novel adaptations. The conservation value of populations inhabiting environmentally marginal areas remains in debate and is closely related to the adaptive potential in changing environments. Strong selection caused by stressful conditions may generate novel adaptations, conferring these populations distinct evolutionary potential and high conservation value under climate change. On the other hand, environmentally marginal populations may be genetically depauperate, with little potential for new adaptations to emerge. Here, we explored the use of ecological niche models (ENMs) linked with common garden experiments to predict and test for genetically determined phenotypic differentiation related to contrasting environmental conditions. To do so, we built an ENM for the alpine plant Silene ciliata in central Spain and conducted common garden experiments, assessing flowering phenology changes and differences in leaf cell resistance to extreme temperatures. The suitability patterns and response curves of the ENM led to the predictions that: (1) the environmentally marginal populations experiencing less snowpack and higher minimum temperatures would have delayed flowering to avoid risks of late-spring frosts and (2) those with higher minimum temperatures and greater potential evapotranspiration would show enhanced cell resistance to high temperatures to deal with physiological stress related to desiccation and heat. The common garden experiments revealed the expected genetically based phenotypic differentiation in flowering phenology. In contrast, they did not show the expected differentiation for cell resistance, but these latter experiments had high variance and hence lower statistical power. The results highlight ENMs as useful tools to identify contrasting putative selective pressures across species ranges. Linking ENMs with common garden experiments provides a theoretically justified and practical way to study adaptive processes, including insights regarding the conservation value of populations inhabiting environmentally marginal areas under ongoing climate change

Treatment with tocilizumab or corticosteroids for COVID-19 patients with hyperinflammatory state: a multicentre cohort study (SAM-COVID-19)

Objectives: The objective of this study was to estimate the association between tocilizumab or corticosteroids and the risk of intubation or death in patients with coronavirus disease 19 (COVID-19) with a hyperinflammatory state according to clinical and laboratory parameters. Methods: A cohort study was performed in 60 Spanish hospitals including 778 patients with COVID-19 and clinical and laboratory data indicative of a hyperinflammatory state. Treatment was mainly with tocilizumab, an intermediate-high dose of corticosteroids (IHDC), a pulse dose of corticosteroids (PDC), combination therapy, or no treatment. Primary outcome was intubation or death; follow-up was 21 days. Propensity score-adjusted estimations using Cox regression (logistic regression if needed) were calculated. Propensity scores were used as confounders, matching variables and for the inverse probability of treatment weights (IPTWs). Results: In all, 88, 117, 78 and 151 patients treated with tocilizumab, IHDC, PDC, and combination therapy, respectively, were compared with 344 untreated patients. The primary endpoint occurred in 10 (11.4%), 27 (23.1%), 12 (15.4%), 40 (25.6%) and 69 (21.1%), respectively. The IPTW-based hazard ratios (odds ratio for combination therapy) for the primary endpoint were 0.32 (95%CI 0.22-0.47; p < 0.001) for tocilizumab, 0.82 (0.71-1.30; p 0.82) for IHDC, 0.61 (0.43-0.86; p 0.006) for PDC, and 1.17 (0.86-1.58; p 0.30) for combination therapy. Other applications of the propensity score provided similar results, but were not significant for PDC. Tocilizumab was also associated with lower hazard of death alone in IPTW analysis (0.07; 0.02-0.17; p < 0.001). Conclusions: Tocilizumab might be useful in COVID-19 patients with a hyperinflammatory state and should be prioritized for randomized trials in this situatio

Métodos y técnicas de monitoreo y predicción temprana en los escenarios de riesgos socionaturales

Esta obra concentra los métodos y las técnicas fundamentales para el seguimiento y monitoreo de las dinámicas de los escenarios de riesgos socionaturales (geológicos e hidrometeorológicos) y tiene como objetivo general orientar, apoyar y acompañar a los directivos y operativos de protección civil en aterrizar las acciones y políticas públicas enfocadas a la gestión del riesgo local de desastre

Innovación en las enseñanzas universitarias: experiencias presentadas en las III Jornadas de Innovación Educativa de la ULL

En este libro se recoge un conjunto de experiencias de innovación educativa desarrolladas en la ULL en el curso 2011-12. Se abordan distintos ámbitos y ramas del conocimiento, y ocupan temáticas variadas que han sido desarrolladas con rigor, y con un claro potencial para su extrapolación a efectos de la mejora educativa en el ámbito universitario. Esta publicación constituye una primera edición de una serie que irá recogiendo las experiencias de innovación educativa de la ULL. Este es un paso relevante para su impulso en nuestra institución, como lo es el de su vinculación con la investigación educativa, para potenciar su publicación en las revistas científicas en este ámbito cada vez más pujante y relevante para las universidades. Sobre todo representan el deseo y el compromiso del profesorado de la ULL para la mejora del proceso educativo mediante la investigación, la evaluación y la reflexión compartida de nuestras prácticas y planteamientos docentes

A global experiment on motivating social distancing during the COVID-19 pandemic

Finding communication strategies that effectively motivate social distancing continues to be a global public health priority during the COVID-19 pandemic. This cross-country, preregistered experiment (n = 25,718 from 89 countries) tested hypotheses concerning generalizable positive and negative outcomes of social distancing messages that promoted personal agency and reflective choices (i.e., an autonomy-supportive message) or were restrictive and shaming (i.e., a controlling message) compared with no message at all. Results partially supported experimental hypotheses in that the controlling message increased controlled motivation (a poorly internalized form of motivation relying on shame, guilt, and fear of social consequences) relative to no message. On the other hand, the autonomy-supportive message lowered feelings of defiance compared with the controlling message, but the controlling message did not differ from receiving no message at all. Unexpectedly, messages did not influence autonomous motivation (a highly internalized form of motivation relying on one’s core values) or behavioral intentions. Results supported hypothesized associations between people’s existing autonomous and controlled motivations and self-reported behavioral intentions to engage in social distancing. Controlled motivation was associated with more defiance and less long-term behavioral intention to engage in social distancing, whereas autonomous motivation was associated with less defiance and more short- and long-term intentions to social distance. Overall, this work highlights the potential harm of using shaming and pressuring language in public health communication, with implications for the current and future global health challenges

Canagliflozin and renal outcomes in type 2 diabetes and nephropathy

BACKGROUND Type 2 diabetes mellitus is the leading cause of kidney failure worldwide, but few effective long-term treatments are available. In cardiovascular trials of inhibitors of sodium–glucose cotransporter 2 (SGLT2), exploratory results have suggested that such drugs may improve renal outcomes in patients with type 2 diabetes. METHODS In this double-blind, randomized trial, we assigned patients with type 2 diabetes and albuminuric chronic kidney disease to receive canagliflozin, an oral SGLT2 inhibitor, at a dose of 100 mg daily or placebo. All the patients had an estimated glomerular filtration rate (GFR) of 30 to &lt;90 ml per minute per 1.73 m2 of body-surface area and albuminuria (ratio of albumin [mg] to creatinine [g], &gt;300 to 5000) and were treated with renin–angiotensin system blockade. The primary outcome was a composite of end-stage kidney disease (dialysis, transplantation, or a sustained estimated GFR of &lt;15 ml per minute per 1.73 m2), a doubling of the serum creatinine level, or death from renal or cardiovascular causes. Prespecified secondary outcomes were tested hierarchically. RESULTS The trial was stopped early after a planned interim analysis on the recommendation of the data and safety monitoring committee. At that time, 4401 patients had undergone randomization, with a median follow-up of 2.62 years. The relative risk of the primary outcome was 30% lower in the canagliflozin group than in the placebo group, with event rates of 43.2 and 61.2 per 1000 patient-years, respectively (hazard ratio, 0.70; 95% confidence interval [CI], 0.59 to 0.82; P=0.00001). The relative risk of the renal-specific composite of end-stage kidney disease, a doubling of the creatinine level, or death from renal causes was lower by 34% (hazard ratio, 0.66; 95% CI, 0.53 to 0.81; P&lt;0.001), and the relative risk of end-stage kidney disease was lower by 32% (hazard ratio, 0.68; 95% CI, 0.54 to 0.86; P=0.002). The canagliflozin group also had a lower risk of cardiovascular death, myocardial infarction, or stroke (hazard ratio, 0.80; 95% CI, 0.67 to 0.95; P=0.01) and hospitalization for heart failure (hazard ratio, 0.61; 95% CI, 0.47 to 0.80; P&lt;0.001). There were no significant differences in rates of amputation or fracture. CONCLUSIONS In patients with type 2 diabetes and kidney disease, the risk of kidney failure and cardiovascular events was lower in the canagliflozin group than in the placebo group at a median follow-up of 2.62 years

Gestión del conocimiento. Perspectiva multidisciplinaria. Volumen 10

El libro “Gestión del Conocimiento. Perspectiva Multidisciplinaria”, Volumen 10, de la Colección Unión Global, es resultado de investigaciones. Los capítulos del libro, son resultados de investigaciones desarrolladas por sus autores. El libro es una publicación internacional, seriada, continua, arbitrada de acceso abierto a todas las áreas del conocimiento, que cuenta con el esfuerzo de investigadores de varios países del mundo, orientada a contribuir con procesos de gestión del conocimiento científico, tecnológico y humanístico que consoliden la transformación del conocimiento en diferentes escenarios, tanto organizacionales como universitarios, para el desarrollo de habilidades cognitivas del quehacer diario. La gestión del conocimiento es un camino para consolidar una plataforma en las empresas públicas o privadas, entidades educativas, organizaciones no gubernamentales, ya sea generando políticas para todas las jerarquías o un modelo de gestión para la administración, donde es fundamental articular el conocimiento, los trabajadores, directivos, el espacio de trabajo, hacia la creación de ambientes propicios para el desarrollo integral de las instituciones

A multi-country test of brief reappraisal interventions on emotions during the COVID-19 pandemic.

The COVID-19 pandemic has increased negative emotions and decreased positive emotions globally. Left unchecked, these emotional changes might have a wide array of adverse impacts. To reduce negative emotions and increase positive emotions, we tested the effectiveness of reappraisal, an emotion-regulation strategy that modifies how one thinks about a situation. Participants from 87 countries and regions (n = 21,644) were randomly assigned to one of two brief reappraisal interventions (reconstrual or repurposing) or one of two control conditions (active or passive). Results revealed that both reappraisal interventions (vesus both control conditions) consistently reduced negative emotions and increased positive emotions across different measures. Reconstrual and repurposing interventions had similar effects. Importantly, planned exploratory analyses indicated that reappraisal interventions did not reduce intentions to practice preventive health behaviours. The findings demonstrate the viability of creating scalable, low-cost interventions for use around the world

Atributos de las especies arbóreas y su carbono almacenado en la vegetación del municipio de Querétaro, México

Abstract Attributes of the shrub and tree species components of the tropical deciduous forest within the Municipality of Querétaro, Querétaro are described. We used a random sampling of 36 sites of natural vegetation with exclusion criteria. Sites were delimited to a 25 m × 25 m quadrant. Within the quadrant, the species of all individuals of the tree and shrub species greater than 150 cm were identified, not taking into account the Cactaceae and Succulents. Measurements were made of the trees: basal diameter, diameter at breast height, total tree height, canopy height and diameter; carbon capture by species was estimated taking into account the climatic site variables, where they grow. Twenty-two species of shrubs and trees were observed, with Acacia schaffneri, Bursera fagaroides, Forestiera phillyreoides, Karwinskia humboldtiana, Dodonaea viscosa and Ipomea murucoides being the most abundant, while the ones with the highest carbon content are species such as: Prosopis laevigata and Leucaena leucocephala and the less abundant were Randia thurberi and Erytrina coralloides. These results are indispensable for developing and designing proposals for reforestation and conservation of the tropical deciduous forest.Resumen Se describen atributos de especies arbustivas y arbóreas, componentes del bosque tropical caducifolio dentro del Municipio de Querétaro, Querétaro. Se utilizó un muestreo aleatorio de 36 sitios de vegetación natural con criterios de exclusión. Para cada sitio se delimitó un cuadrante de 25 m × 25 m. Dentro del cuadrante se identificaron y evaluaron el total de especies arbóreas y arbustivas mayores a 150 cm de altura, excluyendo especies de cactáceas y suculentas. Se evaluaron atributos de los árboles como: diámetro basal, diámetro a la altura del pecho, altura total del árbol, altura de la copa, diámetro de copa y se estimó la capacidad de captura de carbono por especie considerando las variables climáticas del sitio donde crecen. Se observaron 22 especies de arbustos y árboles dentro las que destacan por su abundancia: Acacia schaffneri, Bursera fagaroides, Forestiera phillyreoides, Karwinskia humboldtiana, Dodonaea viscosa e Ipomea murucoides, mientras las que presentan mayor potencial de almacenar carbono son: Prosopis laevigata y Leucaena leucocephala; en contraparte, las menos abundantes fueron: Randia thurberi y Erytrina coralloides. Estos resultados son indispensables para el desarrollo y diseño de propuestas de conservación y reforestación del bosque tropical caducifolio