26 research outputs found
Swift and Fermi observations of the early afterglow of the short Gamma-Ray Burst 090510
We present the observations of GRB090510 performed by the Fermi Gamma-Ray
Space Telescope and the Swift observatory. This is a bright, short burst that
shows an extended emission detected in the GeV range. Furthermore, its optical
emission initially rises, a feature so far observed only in long bursts, while
the X-ray flux shows an initial shallow decrease, followed by a steeper decay.
This exceptional behavior enables us to investigate the physical properties of
the GRB outflow, poorly known in short bursts. We discuss internal shock and
external shock models for the broadband energy emission of this object.Comment: Comments: Submitted to ApJ Letters. Contact Authors: Massimiliano De
Pasquale ([email protected]), Mathew Page ([email protected]), Kenji Toma
([email protected]), Veronique Pelassa ([email protected]). Minor change
in the authorlis
Fermi detection of delayed GeV emission from the short GRB 081024B
We report on the detailed analysis of the high-energy extended emission from
the short Gamma-Ray Burst (GRB) 081024B, detected by the Fermi Gamma-ray Space
Telescope. Historically, this represents the first clear detection of temporal
extended emission from a short GRB. The light curve observed by the Fermi
Gamma-ray Burst Monitor lasts approximately 0.8 seconds whereas the emission in
the Fermi Large Area Telescope lasts for about 3 seconds. Evidence of longer
lasting high-energy emission associated with long bursts has been already
reported by previous experiments. Our observations, together with the earlier
reported study of the bright short GRB 090510, indicate similarities in the
high-energy emission of short and long GRBs and open the path to new
interpretations.Comment: 19 pages, 4 figures, 2 tables. Accepted for publication in Ap
Fermi Observations of GRB 090902B: A Distinct Spectral Component in the Prompt and Delayed Emission
We report on the observation of the bright, long gamma-ray burst, GRB
090902B, by the Gamma-ray Burst Monitor (GBM) and Large Area Telescope (LAT)
instruments on-board the Fermi observatory. This was one of the brightest GRBs
to have been observed by the LAT, which detected several hundred photons during
the prompt phase. With a redshift of z = 1.822, this burst is among the most
luminous detected by Fermi. Time-resolved spectral analysis reveals a
significant power-law component in the LAT data that is distinct from the usual
Band model emission that is seen in the sub-MeV energy range. This power-law
component appears to extrapolate from the GeV range to the lowest energies and
is more intense than the Band component both below 50 keV and above 100
MeV. The Band component undergoes substantial spectral evolution over the
entire course of the burst, while the photon index of the power-law component
remains constant for most of the prompt phase, then hardens significantly
towards the end. After the prompt phase, power-law emission persists in the LAT
data as late as 1 ks post-trigger, with its flux declining as . The
LAT detected a photon with the highest energy so far measured from a GRB,
GeV. This event arrived 82 seconds after the GBM trigger
and 50 seconds after the prompt phase emission had ended in the GBM
band. We discuss the implications of these results for models of GRB emission
and for constraints on models of the Extragalactic Background Light.Comment: Accepted for publication in ApJ Letters. Contact Authors: Elisabetta
Bissaldi ([email protected]), James Chiang ([email protected]),
Francesco de Palma ([email protected]), Sheila McBreen
([email protected]
Multi-messenger observations of a binary neutron star merger
On 2017 August 17 a binary neutron star coalescence candidate (later designated GW170817) with merger time 12:41:04 UTC was observed through gravitational waves by the Advanced LIGO and Advanced Virgo detectors. The Fermi Gamma-ray Burst Monitor independently detected a gamma-ray burst (GRB 170817A) with a time delay of ~1.7 s with respect to the merger time. From the gravitational-wave signal, the source was initially localized to a sky region of 31 deg2 at a luminosity distance of 40+8-8 Mpc and with component masses consistent with neutron stars. The component masses were later measured to be in the range 0.86 to 2.26 Mo. An extensive observing campaign was launched across the electromagnetic spectrum leading to the discovery of a bright optical transient (SSS17a, now with the IAU identification of AT 2017gfo) in NGC 4993 (at ~40 Mpc) less than 11 hours after the merger by the One- Meter, Two Hemisphere (1M2H) team using the 1 m Swope Telescope. The optical transient was independently detected by multiple teams within an hour. Subsequent observations targeted the object and its environment. Early ultraviolet observations revealed a blue transient that faded within 48 hours. Optical and infrared observations showed a redward evolution over ~10 days. Following early non-detections, X-ray and radio emission were discovered at the transientâs position ~9 and ~16 days, respectively, after the merger. Both the X-ray and radio emission likely arise from a physical process that is distinct from the one that generates the UV/optical/near-infrared emission. No ultra-high-energy gamma-rays and no neutrino candidates consistent with the source were found in follow-up searches. These observations support the hypothesis that GW170817 was produced by the merger of two neutron stars in NGC4993 followed by a short gamma-ray burst (GRB 170817A) and a kilonova/macronova powered by the radioactive decay of r-process nuclei synthesized in the ejecta
Practical guidelines for rigor and reproducibility in preclinical and clinical studies on cardioprotection
The potential for ischemic preconditioning to reduce infarct size was first recognized more than 30 years ago. Despite extension of the concept to ischemic postconditioning and remote ischemic conditioning and literally thousands of experimental studies in various species and models which identified a multitude of signaling steps, so far there is only a single and very recent study, which has unequivocally translated cardioprotection to improved clinical outcome as the primary endpoint in patients. Many potential reasons for this disappointing lack of clinical translation of cardioprotection have been proposed, including lack of rigor and reproducibility in preclinical studies, and poor design and conduct of clinical trials. There is, however, universal agreement that robust preclinical data are a mandatory prerequisite to initiate a meaningful clinical trial. In this context, it is disconcerting that the CAESAR consortium (Consortium for preclinicAl assESsment of cARdioprotective therapies) in a highly standardized multi-center approach of preclinical studies identified only ischemic preconditioning, but not nitrite or sildenafil, when given as adjunct to reperfusion, to reduce infarct size. However, ischemic preconditioningâdue to its very natureâcan only be used in elective interventions, and not in acute myocardial infarction. Therefore, better strategies to identify robust and reproducible strategies of cardioprotection, which can subsequently be tested in clinical trials must be developed. We refer to the recent guidelines for experimental models of myocardial ischemia and infarction, and aim to provide now practical guidelines to ensure rigor and reproducibility in preclinical and clinical studies on cardioprotection. In line with the above guideline, we define rigor as standardized state-of-the-art design, conduct and reporting of a study, which is then a prerequisite for reproducibility, i.e. replication of results by another laboratory when performing exactly the same experiment
Multi-messenger Observations of a Binary Neutron Star Merger
On 2017 August 17 a binary neutron star coalescence candidate (later
designated GW170817) with merger time 12:41:04 UTC was observed through
gravitational waves by the Advanced LIGO and Advanced Virgo detectors.
The Fermi Gamma-ray Burst Monitor independently detected a gamma-ray
burst (GRB 170817A) with a time delay of ⌠1.7 {{s}} with respect to
the merger time. From the gravitational-wave signal, the source was
initially localized to a sky region of 31 deg2 at a
luminosity distance of {40}-8+8 Mpc and with
component masses consistent with neutron stars. The component masses
were later measured to be in the range 0.86 to 2.26 {M}ÈŻ
. An extensive observing campaign was launched across the
electromagnetic spectrum leading to the discovery of a bright optical
transient (SSS17a, now with the IAU identification of AT 2017gfo) in NGC
4993 (at ⌠40 {{Mpc}}) less than 11 hours after the merger by the
One-Meter, Two Hemisphere (1M2H) team using the 1 m Swope Telescope. The
optical transient was independently detected by multiple teams within an
hour. Subsequent observations targeted the object and its environment.
Early ultraviolet observations revealed a blue transient that faded
within 48 hours. Optical and infrared observations showed a redward
evolution over âŒ10 days. Following early non-detections, X-ray and
radio emission were discovered at the transientâs position ⌠9
and ⌠16 days, respectively, after the merger. Both the X-ray and
radio emission likely arise from a physical process that is distinct
from the one that generates the UV/optical/near-infrared emission. No
ultra-high-energy gamma-rays and no neutrino candidates consistent with
the source were found in follow-up searches. These observations support
the hypothesis that GW170817 was produced by the merger of two neutron
stars in NGC 4993 followed by a short gamma-ray burst (GRB 170817A) and
a kilonova/macronova powered by the radioactive decay of r-process
nuclei synthesized in the ejecta.</p
Lifetime of muscarinic receptorâG-protein complexes determines coupling efficiency and G-protein subtype selectivity
A limit on the variation of the speed of light arising from quantum gravity effects
A cornerstone of Einstein's special relativity is Lorentz invariance-the postulate that all observers measure exactly the same speed of light in vacuum, independent of photon-energy. While special relativity assumes that there is no fundamental length-scale associated with such invariance, there is a fundamental scale (the Planck scale, l(Planck) approximate to 1.62 x 10(-33) cm or E-Planck = M(Planck)c(2) approximate to 1.22 x 10(19) GeV), at which quantum effects are expected to strongly affect the nature of space-time. There is great interest in the (not yet validated) idea that Lorentz invariance might break near the Planck scale. A key test of such violation of Lorentz invariance is a possible variation of photon speed with energy(1-7). Even a tiny variation in photon speed, when accumulated over cosmological light-travel times, may be revealed by observing sharp features in gamma-ray burst (GRB) light-curves(2). Here we report the detection of emission up to similar to 31GeV from the distant and short GRB090510. We find no evidence for the violation of Lorentz invariance, and place a lower limit of 1.2E(Planck) on the scale of a linear energy dependence (or an inverse wavelength dependence), subject to reasonable assumptions about the emission (equivalently we have an upper limit of l(Planck)/1.2 on the length scale of the effect). Our results disfavour quantum-gravity theories(3,6,7) in which the quantum nature of space-time on a very small scale linearly alters the speed of light.Peer reviewedSubmitted Versio