52 research outputs found

    Electrical resistance tomography-based multi-modality sensor and drift flux model for measurement of oil–gas–water flow

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    From IOP Publishing via Jisc Publications RouterHistory: received 2022-01-08, revised 2022-05-14, oa-requested 2022-05-16, accepted 2022-05-30, epub 2022-06-14, open-access 2022-06-14, ppub 2022-09-01Publication status: PublishedFunder: University of Chester; doi: http://dx.doi.org/10.13039/100010333Abstract: This paper proposes a novel method to measure each constituent of an oil–gas–water mixture in a water continuous flow, typically encountered in many processes. It deploys a dual-plane electrical resistance tomography sensor for measuring dispersed phase volume fraction and velocity; a gradiomanometer flow density meter and a drift flux model to estimate slip velocities; with absolute pressure and temperature measurements. These data are fused to estimate constituent volume flow rates. Other commonly used operational parameters can be further derived: water cut or water liquid ratio (WLR) and gas volume fraction (GVF). Trials are described for flow rates of water 5–10 m3 h−1; oil 2–10 m3 h−1 and gas 1–15 m3 h−1. The comparative results are included with published data from the Schlumberger Gould Research flow facility. The paper proposes the use of the described configuration for measurement of volume flow rates in oil–gas–water flows with an absolute error of ±10% within GVF 9%–85% and WLR > 45%

    Rubric for the evaluation of the TGW

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    Rúbrica para la evaluación del Trabajo Grupal Tutorizado de la asignatura de Psicología de la Intervención Social y ComunitariaRubric for the evaluation of the Group Work Tutorials of the Psychology of Social and Community Intervention course

    Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study

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    Background: The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and pulmonary complication rates in patients with perioperative SARS-CoV-2 infection. Methods: This international, multicentre, cohort study at 235 hospitals in 24 countries included all patients undergoing surgery who had SARS-CoV-2 infection confirmed within 7 days before or 30 days after surgery. The primary outcome measure was 30-day postoperative mortality and was assessed in all enrolled patients. The main secondary outcome measure was pulmonary complications, defined as pneumonia, acute respiratory distress syndrome, or unexpected postoperative ventilation. Findings: This analysis includes 1128 patients who had surgery between Jan 1 and March 31, 2020, of whom 835 (74·0%) had emergency surgery and 280 (24·8%) had elective surgery. SARS-CoV-2 infection was confirmed preoperatively in 294 (26·1%) patients. 30-day mortality was 23·8% (268 of 1128). Pulmonary complications occurred in 577 (51·2%) of 1128 patients; 30-day mortality in these patients was 38·0% (219 of 577), accounting for 81·7% (219 of 268) of all deaths. In adjusted analyses, 30-day mortality was associated with male sex (odds ratio 1·75 [95% CI 1·28–2·40], p\textless0·0001), age 70 years or older versus younger than 70 years (2·30 [1·65–3·22], p\textless0·0001), American Society of Anesthesiologists grades 3–5 versus grades 1–2 (2·35 [1·57–3·53], p\textless0·0001), malignant versus benign or obstetric diagnosis (1·55 [1·01–2·39], p=0·046), emergency versus elective surgery (1·67 [1·06–2·63], p=0·026), and major versus minor surgery (1·52 [1·01–2·31], p=0·047). Interpretation: Postoperative pulmonary complications occur in half of patients with perioperative SARS-CoV-2 infection and are associated with high mortality. Thresholds for surgery during the COVID-19 pandemic should be higher than during normal practice, particularly in men aged 70 years and older. Consideration should be given for postponing non-urgent procedures and promoting non-operative treatment to delay or avoid the need for surgery. Funding: National Institute for Health Research (NIHR), Association of Coloproctology of Great Britain and Ireland, Bowel and Cancer Research, Bowel Disease Research Foundation, Association of Upper Gastrointestinal Surgeons, British Association of Surgical Oncology, British Gynaecological Cancer Society, European Society of Coloproctology, NIHR Academy, Sarcoma UK, Vascular Society for Great Britain and Ireland, and Yorkshire Cancer Research

    Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

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    Background: In an era of shifting global agendas and expanded emphasis on non-communicable diseases and injuries along with communicable diseases, sound evidence on trends by cause at the national level is essential. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) provides a systematic scientific assessment of published, publicly available, and contributed data on incidence, prevalence, and mortality for a mutually exclusive and collectively exhaustive list of diseases and injuries. Methods: GBD estimates incidence, prevalence, mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs) due to 369 diseases and injuries, for two sexes, and for 204 countries and territories. Input data were extracted from censuses, household surveys, civil registration and vital statistics, disease registries, health service use, air pollution monitors, satellite imaging, disease notifications, and other sources. Cause-specific death rates and cause fractions were calculated using the Cause of Death Ensemble model and spatiotemporal Gaussian process regression. Cause-specific deaths were adjusted to match the total all-cause deaths calculated as part of the GBD population, fertility, and mortality estimates. Deaths were multiplied by standard life expectancy at each age to calculate YLLs. A Bayesian meta-regression modelling tool, DisMod-MR 2.1, was used to ensure consistency between incidence, prevalence, remission, excess mortality, and cause-specific mortality for most causes. Prevalence estimates were multiplied by disability weights for mutually exclusive sequelae of diseases and injuries to calculate YLDs. We considered results in the context of the Socio-demographic Index (SDI), a composite indicator of income per capita, years of schooling, and fertility rate in females younger than 25 years. Uncertainty intervals (UIs) were generated for every metric using the 25th and 975th ordered 1000 draw values of the posterior distribution. Findings: Global health has steadily improved over the past 30 years as measured by age-standardised DALY rates. After taking into account population growth and ageing, the absolute number of DALYs has remained stable. Since 2010, the pace of decline in global age-standardised DALY rates has accelerated in age groups younger than 50 years compared with the 1990–2010 time period, with the greatest annualised rate of decline occurring in the 0–9-year age group. Six infectious diseases were among the top ten causes of DALYs in children younger than 10 years in 2019: lower respiratory infections (ranked second), diarrhoeal diseases (third), malaria (fifth), meningitis (sixth), whooping cough (ninth), and sexually transmitted infections (which, in this age group, is fully accounted for by congenital syphilis; ranked tenth). In adolescents aged 10–24 years, three injury causes were among the top causes of DALYs: road injuries (ranked first), self-harm (third), and interpersonal violence (fifth). Five of the causes that were in the top ten for ages 10–24 years were also in the top ten in the 25–49-year age group: road injuries (ranked first), HIV/AIDS (second), low back pain (fourth), headache disorders (fifth), and depressive disorders (sixth). In 2019, ischaemic heart disease and stroke were the top-ranked causes of DALYs in both the 50–74-year and 75-years-and-older age groups. Since 1990, there has been a marked shift towards a greater proportion of burden due to YLDs from non-communicable diseases and injuries. In 2019, there were 11 countries where non-communicable disease and injury YLDs constituted more than half of all disease burden. Decreases in age-standardised DALY rates have accelerated over the past decade in countries at the lower end of the SDI range, while improvements have started to stagnate or even reverse in countries with higher SDI. Interpretation: As disability becomes an increasingly large component of disease burden and a larger component of health expenditure, greater research and developm nt investment is needed to identify new, more effective intervention strategies. With a rapidly ageing global population, the demands on health services to deal with disabling outcomes, which increase with age, will require policy makers to anticipate these changes. The mix of universal and more geographically specific influences on health reinforces the need for regular reporting on population health in detail and by underlying cause to help decision makers to identify success stories of disease control to emulate, as well as opportunities to improve. Funding: Bill & Melinda Gates Foundation. © 2020 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licens

    Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950-2019 : a comprehensive demographic analysis for the Global Burden of Disease Study 2019

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    Background: Accurate and up-to-date assessment of demographic metrics is crucial for understanding a wide range of social, economic, and public health issues that affect populations worldwide. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 produced updated and comprehensive demographic assessments of the key indicators of fertility, mortality, migration, and population for 204 countries and territories and selected subnational locations from 1950 to 2019. Methods: 8078 country-years of vital registration and sample registration data, 938 surveys, 349 censuses, and 238 other sources were identified and used to estimate age-specific fertility. Spatiotemporal Gaussian process regression (ST-GPR) was used to generate age-specific fertility rates for 5-year age groups between ages 15 and 49 years. With extensions to age groups 10–14 and 50–54 years, the total fertility rate (TFR) was then aggregated using the estimated age-specific fertility between ages 10 and 54 years. 7417 sources were used for under-5 mortality estimation and 7355 for adult mortality. ST-GPR was used to synthesise data sources after correction for known biases. Adult mortality was measured as the probability of death between ages 15 and 60 years based on vital registration, sample registration, and sibling histories, and was also estimated using ST-GPR. HIV-free life tables were then estimated using estimates of under-5 and adult mortality rates using a relational model life table system created for GBD, which closely tracks observed age-specific mortality rates from complete vital registration when available. Independent estimates of HIV-specific mortality generated by an epidemiological analysis of HIV prevalence surveys and antenatal clinic serosurveillance and other sources were incorporated into the estimates in countries with large epidemics. Annual and single-year age estimates of net migration and population for each country and territory were generated using a Bayesian hierarchical cohort component model that analysed estimated age-specific fertility and mortality rates along with 1250 censuses and 747 population registry years. We classified location-years into seven categories on the basis of the natural rate of increase in population (calculated by subtracting the crude death rate from the crude birth rate) and the net migration rate. We computed healthy life expectancy (HALE) using years lived with disability (YLDs) per capita, life tables, and standard demographic methods. Uncertainty was propagated throughout the demographic estimation process, including fertility, mortality, and population, with 1000 draw-level estimates produced for each metric. Findings: The global TFR decreased from 2·72 (95% uncertainty interval [UI] 2·66–2·79) in 2000 to 2·31 (2·17–2·46) in 2019. Global annual livebirths increased from 134·5 million (131·5–137·8) in 2000 to a peak of 139·6 million (133·0–146·9) in 2016. Global livebirths then declined to 135·3 million (127·2–144·1) in 2019. Of the 204 countries and territories included in this study, in 2019, 102 had a TFR lower than 2·1, which is considered a good approximation of replacement-level fertility. All countries in sub-Saharan Africa had TFRs above replacement level in 2019 and accounted for 27·1% (95% UI 26·4–27·8) of global livebirths. Global life expectancy at birth increased from 67·2 years (95% UI 66·8–67·6) in 2000 to 73·5 years (72·8–74·3) in 2019. The total number of deaths increased from 50·7 million (49·5–51·9) in 2000 to 56·5 million (53·7–59·2) in 2019. Under-5 deaths declined from 9·6 million (9·1–10·3) in 2000 to 5·0 million (4·3–6·0) in 2019. Global population increased by 25·7%, from 6·2 billion (6·0–6·3) in 2000 to 7·7 billion (7·5–8·0) in 2019. In 2019, 34 countries had negative natural rates of increase; in 17 of these, the population declined because immigration was not sufficient to counteract the negative rate of decline. Globally, HALE increased from 58·6 years (56·1–60·8) in 2000 to 63·5 years (60·8–66·1) in 2019. HALE increased in 202 of 204 countries and territories between 2000 and 2019

    COVID-19 Vaccination Among Diverse Population Groups in the Northern Governorates of Iraq

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    Objectives: The present study was carried out to investigate COVID-19 vaccination coverage among populations of internally displaced persons (IDPs), refugees, and host communities in northern Iraq and the related underlying factors.Methods: Through a cross-sectional study conducted in five governorates in April–May 2022, 4,564 individuals were surveyed. Data were collected through an adapted questionnaire designed to gather data on participants.Results: 4,564 subjects were included (59.55% were 19–45 years old; 54.51% male). 50.48% of the participants (51.49% of host communities, 48.83% of IDPs, and 45.87% of refugees) had been vaccinated with at least one dose of COVID-19 vaccine. 40.84% of participants (42.28% of host communities, 35.75% of IDPs, and 36.14% of refugees) had been vaccinated by two doses, and 1.56% (1.65% of host communities, 0.93% of IDPs, and 1.46% of refugees) were vaccinated with three doses.Conclusion: Sociodemographic factors including age, gender, education, occupation, and nationality could affect vaccination coverage. Moreover, higher acceptance rate of vaccination is associated with belief in vaccine safety and effectiveness and trust in the ability of the vaccine to prevent complications

    Croissance et caractérisation des fibres monocristallines LuAG dopées par la technique de micro-pulling down

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    Single crystalline Cerium doped and undoped lutetium aluminum garnet fibers (Lu3Al5O12 - LuAG) grown by the micro-pulling-down technique show promising results for the development of future calorimeters due to its high scintillation properties. But this growth technique is complex and requires deep investigation for improving further the light properties of the grown fiber. After adjusting the growth temperature, the three main parameters studied were the cerium concentration, the growth rate, and the crystal orientation (fixed by the see). Best results were obtained by a combination of relatively low pulling speed (0.25mm/min), diluted cerium content of ~0.01 at.% and oriented LuAG seed. These optimized fibers, which could be of 1 or 2 mm diameter and up to 22 cm long, showed a much smoother surface and reduced cracks and/or defects. In the best cases, light attenuation measurements indicated enhanced attenuation length which could be higher than 30 cm. Moreover, these fibers were found to display improved radiation hardnessLes fibres monocristallines d'oxyde de lutécium et aluminium (Lu3Al5O12 - LuAG), non dopées ou intentionnellement dopées au cérium, élaborées par la technique de micro-pulling down sont de sérieuses candidates pour le développement de nouvelles générations de calorimètres à scintillation. Cependant, cette technique de croissance est complexe et nécessite une étude approfondie pour améliorer les propriétés optiques de ces fibres. Après avoir ajusté la température de croissance, les paramètres principaux étudiés furent la concentration en Cerium, la vitesse de croissance et l'orientation du cristal (fixé par le germe). Les meilleurs résultats ont été obtenus en combinant une vitesse de croissance relativement lente (0,25 mm/min), une teneur en Ce assez faible (~0.01 at.%) et une orientation du cristal de LuAG. Ces fibres optimisées, de diamètre 1 ou 2 mm et de longueur atteignant 22 cm, présentaient une surface plus lisse et une densité de défauts et/ou cracks réduite. Dans les meilleurs cas, les mesures d'atténuation lumineuse ont montré une longueur d'atténuation pouvant dépasser 30 cm. Ces fibres se sont montrées également plus résistantes aux radiation

    Vīrusu nozīme mutes lichen planus patoģenēzē

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    ZobārstniecībaVeselības aprūpeDentistryHealth CareŠajā pētījumā lasītājs tiks informēts par vairākiem perorālās ķērpju plāna aspektiem, piemēram, dažādiem patoģenēzes mehānismiem un dažādiem klīniskiem attēliem. Tomēr tas galvenokārt tiks koncentrēts uz iekšķīgi lietojamo ķērpju etioloģiju, konkrētāk, dažādu vīrusu lomu perorālās ķērpju planus patoģenēzē. Perorālais ķērpju ķērpis ir hroniska autoimūna iekaisuma slimība ar nezināmiem etioloģiskiem faktoriem, taču vīrusi jau kādu laiku ir bijuši interesants faktors, un virkne vīrusu ir pārbaudīti, un šajā pētījumā lasītājs uzzinās, kā šie vīrusi patiešām ir saistīti ar perorālo ķērpis planus.This research paper will inform the reader about several aspects of oral lichen planus like it's different pathogenesis mechanisms and various clinical presentation. However it will be mainly focused on the etiology of oral lichen planus more specifically the role of different viruses in oral lichen planus pathogenesis. Oral lichen planus is a chronic autoimmnune inflammatory disease with unknown etiological factors, but viruses have been an interesting factor for a while now and a number of viruses went through investigations and in this research paper the reader will find out how these viruses genuinely connected to oral lichen planus
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