591 research outputs found
Higgs production in CP-violating supersymmetric cascade decays: probing the `open hole' at the Large Hadron Collider
- Author
- A Bartl
- A Datta
- A Datta
- A Pilaftsis
- A Pilaftsis
- A Pilaftsis
- A Pilaftsis
- A Roeck De
- AC Fowler
- D Chang
- DA Demir
- DA Demir
- DK Ghosh
- DK Ghosh
- E Accomando
- F Deppisch
- FF Deppisch
- G Abbiendi
- G Weiglein
- GD Kribs
- GD Kribs
- GL Kane
- HL Lai
- J Pumplin
- JR Ellis
- JR Ellis
- JS Lee
- JS Lee
- JS Lee
- KE Williams
- M Brhlik
- M Frank
- ML Mangano
- MS Carena
- MS Carena
- O Kittel
- P Bandyopadhyay
- P Bandyopadhyay
- P Bandyopadhyay
- P Draper
- P Nath
- Priyotosh Bandyopadhyay
- PZ Skands
- R Barate
- S Abel
- S Heinemeyer
- S Pokorski
- S Schael
- SP Das
- SP Das
- SW Ham
- SW Ham
- SY Choi
- SY Choi
- SY Choi
- T Falk
- T Hahn
- T Ibrahim
- T Ibrahim
- T Ibrahim
- U Chattopadhyay
- Y Kizukuri
- Z Li
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 09/12/2011
- Field of study
A benchmark CP-violating supersymmetric scenario (known as 'CPX-scenario' in
the literature) is studied in the context of the Large Hadron Collider (LHC).
It is shown that the LHC, with low to moderate accumulated luminosity, will be
able to probe the existing `hole' in the mh1ââ-tanÎČ plane, which
cannot be ruled out by the LEP data. We explore the parameter space with
cascade decay of third generation squarks and gluino with CP-violating decay
branching fractions. We propose a multi-channel analysis to probe this
parameter space some of which are background free at an integrated luminosity
of 5-10 fbâ1. Specially, multi-lepton final states (3\l,\, 4\l and like
sign di-lepton) are almost background free and have 5Ï reach for the
corresponding signals with very early data of LHC for both 14 TeV and 7 TeV
center of mass energy.Comment: 24 pages, 9 figures, references added as in the journal versio
Non-resonant leptogenesis in seesaw models with an almost conserved B-L
- Author
- A Abada
- A Abada
- A Anisimov
- A Pilaftsis
- A Pilaftsis
- A Pilaftsis
- A Simone De
- CS Fong
- CS Fong
- D Aristizabal
- E Komatsu
- E Nardi
- E Nardi
- E Nardi
- F Aguila del
- FF Deppisch
- GF Giudice
- J Bernabeu
- J Kersten
- J Racker
- J Racker
- JM FrĂšre
- JR Ellis
- L Covi
- M Fukugita
- M Kawasaki
- MB Gavela
- MC Gonzalez-Garcia
- MC Gonzalez-Garcia
- MY Khlopov
- R Barbieri
- RN Mohapatra
- S Antusch
- S Blanchet
- S Davidson
- S Davidson
- S Davidson
- T Asaka
- T Endoh
- T Hambye
- T Han
- W BuchmĂŒller
- W BuchmĂŒller
- W BuchmĂŒller
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2013
- Field of study
We review the motivations and some results on leptogenesis in seesaw models
with an almost conserved lepton number. The paper is based on a talk given at
the 5th International Symposium on Symmetries in Subatomic Physics, SSP2012.Comment: 8 pages, 1 figure. Published in the proceedings of the 5th
International Symposium on Symmetries in Subatomic Physics, SSP201
Sleep habits in native brazilian bororo children
- Author
- Albisetti C
- AraĂșjo FR
- Billingham RE
- Bordignon M
- Byard RW
- Canuso R
- CARLOS EDUARDO VILELA GAUDIOSO
- Conder K
- Cooper R
- Ellis EM
- Genta MB
- Gilford MC
- Gonçalves JRS
- JOSĂ CARLOS ROSA PIRES DE SOUZA
- Levi-Strauss C
- Lozoff B
- Mangolim O
- McKenna JJ
- McKenna JJ
- Petersen SA
- Proença C
- Rath FHJ
- ReimĂŁo R
- ReimĂŁo R
- ReimĂŁo R
- ReimĂŁo R
- ReimĂŁo R
- ReimĂŁo R
- Ribeiro D
- Rona RJ
- RUBENS REIMĂO
- Schachter FF
- Silva JR
- Stein MT
- Viertler RB
- Zuckerman B
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Measurement of the inclusive and dijet cross-sections of b-jets in pp collisions at sqrt(s) = 7 TeV with the ATLAS detector
- Author
- Aad G
- Abbott B
- Abdallah J
- Abdelalim AA
- Abdesselam A
- Abdinov O
- Abi B
- Abolins M
- Abramowicz H
- Abreu H
- Acerbi E
- Acharya BS
- Ackers M
- Adams DL
- Addy TN
- Adelman J
- Aderholz M
- Adomeit S
- Adragna P
- Adye T
- Aefsky S
- Aguilar-Saavedra JA
- Aharrouche M
- Ahlen SP
- Ahles F
- Ahmad A
- Ahsan M
- Aielli G
- Akdogan T
- Akesson TPA
- Akimoto G
- Akimov AV
- Alam MA
- Alam MS
- Albrand S
- Aleksa M
- Aleksandrov IN
- Aleppo M
- Alessandria F
- Alexa C
- Alexander G
- Alexandre G
- Alexopoulos T
- Alhroob M
- Aliev M
- Alimonti G
- Alison J
- Aliyev M
- Allport PP
- Allwood-Spiers SE
- Almenar CC
- Almond J
- Aloisio A
- Alon R
- Alonso A
- Alonso J
- Alviggi MG
- Amako K
- Amaral P
- Amelung C
- Ammosov VV
- Amorim A
- Amoros G
- Amram N
- Anastopoulos C
- Andari N
- Andeen T
- Anders CF
- Anderson KJ
- Andreazza A
- Andrei V
- Andrieux M-L
- Anduaga XS
- Angerami A
- Anghinolfi F
- Anh TV
- Anjos N
- Annovi A
- Antonaki A
- Antonelli M
- Antonelli S
- Antos J
- Anulli F
- Aoun S
- Apolle R
- Arabidze G
- Aracena I
- Arai Y
- Arce ATH
- Archambault JP
- Arfaoui S
- Arguin J-F
- Arik E
- Arik M
- Armbruster AJ
- Arms KE
- Armstrong SR
- Arnaez O
- Arnault C
- Artamonov A
- Artoni G
- Arutinov D
- Asai S
- Asfandiyarov R
- Ask S
- Asman B
- Asquith L
- Assamagan K
- Astbury A
- Astvatsatourov A
- Atoian G
- Aubert B
- Auerbach B
- Auge E
- Augsten K
- Aurousseau M
- Austin N
- Avramidou R
- Axen D
- Ay C
- Azuelos G
- Azuma Y
- Baak MA
- Baccaglioni G
- Bacci C
- Bach AM
- Bachacou H
- Bachas K
- Bachy G
- Backes M
- Badescu E
- Bagnaia P
- Bahinipati S
- Bai Y
- Bailey DC
- Bain T
- Baines JT
- Baker OK
- Baker S
- Banas E
- Banerjee P
- Banerjee S
- Banfi D
- Bangert A
- Bansal V
- Bansil HS
- Barak L
- Baranov SP
- Barashkou A
- Barber T
- Barberio EL
- Barberis D
- Barbero M
- Bardin DY
- Barillari T
- Barisonzi M
- Barklow T
- Barlow N
- Barnett BM
- Barnett RM
- Baroncelli A
- Barr AJ
- Barreiro F
- Barrera CO
- Barrillon P
- Bartoldus R
- Barton AE
- Bartsch D
- Bates RL
- Batkova L
- Batley JR
- Battaglia A
- Battistin M
- Battistoni G
- Bauer F
- Bawa HS
- Beare B
- Beau T
- Beauchemin PH
- Beccherle R
- Bechtle P
- Beck HP
- Beckingham M
- Becks KH
- Beddall A
- Beddall AJ
- Bednyakov VA
- Bee C
- Begel M
- Behera PK
- Beimforde M
- Belanger-Champagne C
- Belenguer MJ
- Belhorma B
- Bell PJ
- Bell WH
- Bella G
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- Bellina F
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- Bellomo M
- Belloni A
- Belotskiy K
- Beltramello O
- Ben Ami S
- Benary O
- Benchekroun D
- Benchouk C
- Bendel M
- Benedict BH
- Benekos N
- Benhammou Y
- Benjamin DP
- Benoit M
- Bensinger JR
- Benslama K
- Bentvelsen S
- Berge D
- Berger N
- Berghaus F
- Berglund E
- Beringer J
- Bernardet K
- Bernat P
- Bernhard R
- Bernius C
- Berry T
- Bertin A
- Bertinelli F
- Bertolucci F
- Besana MI
- Besson N
- Bethke S
- Bhimji W
- Bianchi RM
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- Biebel O
- Biesiada J
- Biglietti M
- Bilokon H
- Bindi M
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- Bitenc U
- Black KM
- Blair RE
- Blanchard J-B
- Blanchot G
- Blocker C
- Blocki J
- Blondel A
- Blum W
- Blumenschein U
- Boaretto C
- Bobbink GJ
- Bobrovnikov VB
- Bocci A
- Bock R
- Boddy CR
- Boehler M
- Boek J
- Boelaert N
- Boeser S
- Bogaerts JA
- Bogdanchikov A
- Bogouch A
- Bohm C
- Boisvert V
- Bold T
- Boldea V
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- Boonekamp M
- Boorman G
- Booth CN
- Booth JRA
- Booth P
- Bordoni S
- Borer C
- Borisov A
- Borissov G
- Borjanovic I
- Borroni S
- Bos K
- Boscherini D
- Bosman M
- Boterenbrood H
- Botterill D
- Bouchami J
- Boudreau J
- Bouhova-Thacker EV
- Boulahouache C
- Bourdarios C
- Bousson N
- Boveia A
- Boyd J
- Boyko IR
- Bozhko NI
- Bozovic-Jelisavcic I
- Braccini S
- Bracinik J
- Braem A
- Brambilla E
- Branchini P
- Branco MDO
- Brandenburg GW
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- Bratzler U
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- Bressler S
- Breton D
- Brett ND
- Bright-Thomas PG
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- Brochu FM
- Brock I
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- Brodbeck TJ
- Brodet E
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- Brown G
- Brubaker E
- Bruncko D
- Bruneliere R
- Brunet S
- Bruni A
- Bruni G
- Bruschi M
- Buanes T
- Bucci F
- Buchanan J
- Buchanan NJ
- Buchholz P
- Buckingham RM
- Buckley AG
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- Budagov IA
- Budick B
- Buescher V
- Bueso XP
- Bugge L
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- Bulekov O
- Bunse M
- Buran T
- Burckhart H
- Burdin S
- Burgess T
- Burke S
- Busato E
- Bussey P
- Buszello CP
- Butin F
- Butler B
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- Buttar CM
- Butterworth JM
- Buttinger W
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- Cabrera Urban S
- Caccia M
- Caforio D
- Cakir IT
- Cakir O
- Calafiura P
- Calderini G
- Calfayan P
- Calkins R
- Caloba LP
- Caloi R
- Calvet D
- Calvet S
- Camard A
- Camarri P
- Cambiaghi M
- Cameron D
- Camillocci ES
- Cammin J
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- Canelli F
- Canepa A
- Cantero J
- Capasso L
- Caprini I
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- Caprio M
- Capriotti D
- Capua M
- Caputo R
- Caramarcu C
- Cardarelli R
- Carli T
- Carlino G
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- Casadei D
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- Castaneda-Miranda E
- Castanheira MTD
- Castillo Gimenez V
- Castillo LRF
- Castro NF
- Cataldi G
- Cataneo F
- Catinaccio A
- Catmore JR
- Cattai A
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- Caughron S
- Cavalcanti TP
- Cavallari A
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- Cavasinni V
- Cazzato A
- Ceradini F
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- Charlton DG
- Chavda V
- Cheatham S
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- Chekulaev SV
- Chelkov GA
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- Chernyatin V
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- Zhemchugov A
- Zheng S
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- Zieminska D
- Zilka B
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- Zimmermann S
- Ziolkowski M
- Zitoun R
- Zivkovic L
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- zur Nedden M
- Zutshi V
- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 31/12/2010
- Field of study
The inclusive and dijet production cross-sections have been measured for jets
containing b-hadrons (b-jets) in proton-proton collisions at a centre-of-mass
energy of sqrt(s) = 7 TeV, using the ATLAS detector at the LHC. The
measurements use data corresponding to an integrated luminosity of 34 pb^-1.
The b-jets are identified using either a lifetime-based method, where secondary
decay vertices of b-hadrons in jets are reconstructed using information from
the tracking detectors, or a muon-based method where the presence of a muon is
used to identify semileptonic decays of b-hadrons inside jets. The inclusive
b-jet cross-section is measured as a function of transverse momentum in the
range 20 < pT < 400 GeV and rapidity in the range |y| < 2.1. The bbbar-dijet
cross-section is measured as a function of the dijet invariant mass in the
range 110 < m_jj < 760 GeV, the azimuthal angle difference between the two jets
and the angular variable chi in two dijet mass regions. The results are
compared with next-to-leading-order QCD predictions. Good agreement is observed
between the measured cross-sections and the predictions obtained using POWHEG +
Pythia. MC@NLO + Herwig shows good agreement with the measured bbbar-dijet
cross-section. However, it does not reproduce the measured inclusive
cross-section well, particularly for central b-jets with large transverse
momenta.Comment: 10 pages plus author list (21 pages total), 8 figures, 1 table, final
version published in European Physical Journal
Jet energy measurement with the ATLAS detector in proton-proton collisions at root s=7 TeV
- Author
- Aad G
- Abbott B
- Abdallah J
- Abdelalim AA
- Abdesselam A
- Abdinov O
- Abi B
- Abolins M
- Abramowicz H
- Abreu H
- Acerbi E
- Acharya BS
- Adams DL
- Addy TN
- Adelman J
- Aderholz M
- Adomeit S
- Adragna P
- Adye T
- Aefsky S
- Aguilar-Saavedra JA
- Aharrouche M
- Ahlen SP
- Ahles F
- Ahmad A
- Ahsan M
- Aielli G
- Akdogana T
- Akesson TPA
- Akimoto G
- Akimov AV
- Akiyama A
- Aktas A
- Alam MA
- Alam MS
- Albert J
- Albrand S
- Aleksa M
- Aleksandrov IN
- Alessandria F
- Alexa C
- Alexander G
- Alexandre G
- Alexopoulos T
- Alhroob M
- Aliev M
- Alimonti G
- Alison J
- Aliyev M
- Allport PP
- Allwood-Spiers SE
- Almenar CC
- Almond J
- Aloisio A
- Alon R
- Alonso A
- Alviggi MG
- Amako K
- Amaral P
- Amelung C
- Ammosov VV
- Amorim A
- Amoros G
- Amram N
- Anastopoulos C
- Ancu LS
- Andari N
- Andeen T
- Anders CF
- Anders G
- Anderson KJ
- Andreazza A
- Andrei V
- Andrieux M-L
- Anduaga XS
- Angerami A
- Anghinolfi F
- Anh TV
- Anjos N
- Annovi A
- Antonaki A
- Antonelli M
- Antonov A
- Antos J
- Anulli F
- Aoun S
- Apolle R
- Arabidze G
- Aracena I
- Arai Y
- Aranda CP
- Arce ATH
- Archambault JP
- Arfaoui S
- Arguin J-F
- Arik E
- Arik M
- Armbruster AJ
- Arnaez O
- Arnault C
- Artamonov A
- Artoni G
- Arutinov D
- Asai S
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- Baak MA
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- Bach AM
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- Bachy G
- Backes M
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- Badescu E
- Bagnaia P
- Bahinipati S
- Bai Y
- Bailey DC
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- Baines JT
- Baker MD
- Baker OK
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- Banfi D
- Bangert A
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- Bardin DY
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- Barnett BM
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- Baroncelli A
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- Barton AE
- Bartsch D
- Bartsch V
- Bates RL
- Batkova L
- Batley JR
- Battaglia A
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- Battistoni G
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- Beauchemin PH
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- Benjamin DP
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- Biglietti M
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- Blanchard J-B
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- Bobbink GJ
- Bobrovnikov VB
- Bocchetta SS
- Bocci A
- Boddy CR
- Boehler M
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- Boelaert N
- Boeriu OEV
- Boeser S
- Bogaerts JA
- Bogdanchikov A
- Bogouch A
- Bohm C
- Boisvert V
- Bold T
- Boldea V
- Bolnet NM
- Bona M
- Bondarenko VG
- Bondioli M
- Boonekamp M
- Boorman G
- Booth CN
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/03/2013
- Field of study
The jet energy scale and its systematic uncertainty are determined for jets measured with the ATLAS detector at the LHC in proton-proton collision data at a centre-of-mass energy of âs = 7TeV corresponding to an integrated luminosity of 38 pb-1. Jets are reconstructed with the anti-kt algorithm with distance parameters R=0. 4 or R=0. 6. Jet energy and angle corrections are determined from Monte Carlo simulations to calibrate jets with transverse momenta pTâ„20 GeV and pseudorapidities {pipe}η{pipe}<4. 5. The jet energy systematic uncertainty is estimated using the single isolated hadron response measured in situ and in test-beams, exploiting the transverse momentum balance between central and forward jets in events with dijet topologies and studying systematic variations in Monte Carlo simulations. The jet energy uncertainty is less than 2. 5 % in the central calorimeter region ({pipe}η{pipe}<0. 8) for jets with 60â€pT<800 GeV, and is maximally 14 % for pT<30 GeV in the most forward region 3. 2â€{pipe}η{pipe}<4. 5. The jet energy is validated for jet transverse momenta up to 1 TeV to the level of a few percent using several in situ techniques by comparing a well-known reference such as the recoiling photon pT, the sum of the transverse momenta of tracks associated to the jet, or a system of low-pT jets recoiling against a high-pT jet. More sophisticated jet calibration schemes are presented based on calorimeter cell energy density weighting or hadronic properties of jets, aiming for an improved jet energy resolution and a reduced flavour dependence of the jet response. The systematic uncertainty of the jet energy determined from a combination of in situ techniques is consistent with the one derived from single hadron response measurements over a wide kinematic range. The nominal corrections and uncertainties are derived for isolated jets in an inclusive sample of high-pT jets. Special cases such as event topologies with close-by jets, or selections of samples with an enhanced content of jets originating from light quarks, heavy quarks or gluons are also discussed and the corresponding uncertainties are determined. © 2013 CERN for the benefit of the ATLAS collaboration
750 GeV diphotons and supersymmetric grand unification
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Search for new phenomena in final states with an energetic jet and large missing transverse momentum in pp collisions at â s = 8 TeV with the ATLAS detector
- Author
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- Whiteson D
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- Wiedenmann W
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- Wolff R
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- Wong VWS
- Woods NL
- Worm SD
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- Wraight K
- Wu SL
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- Wyatt TR
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- Xella S
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- Xiao X
- Xiotidis I
- Xu D
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- Yallup DP
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- Yamaguchi Y
- Yamamoto A
- Yamatani M
- Yamazaki T
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- Yao W-M
- Yap YC
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- Yeletskikh I
- Yexley MR
- Yigitbasi E
- Yildiz HD
- Yorita K
- Yoshihara K
- Young C
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- Yu J
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- Yue X
- Zaazoua M
- Zabinski B
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- Zahreddine J
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- Zakharchuk N
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- Zaripovas DR
- Zeissner S
- Zeitnitz C
- Zemaityte G
- Zeng JC
- Zenin O
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- Zerwas D
- Zgubic M
- Zhang B
- Zhang DF
- Zhang G
- Zhang H
- Zhang J
- Zhang L
- Zhang M
- Zhang R
- Zhang S
- Zhang X
- Zhang Y
- Zhang Z
- Zhao P
- Zhao Z
- Zhemchugov A
- Zheng Z
- Zhong D
- Zhou B
- Zhou C
- Zhou M
- Zhou MS
- Zhou N
- Zhou Y
- Zhu C
- Zhu CG
- Zhu H
- Zhu HL
- Zhu J
- Zhu Y
- Zhuang X
- Zhukov K
- Zhulanov V
- Zieminska D
- Zimine N
- Zimmermann S
- Zinonos Z
- Ziolkowski M
- Zivkovic L
- Zobernig G
- Zoccoli A
- Zoch K
- Zorbas TG
- Zou R
- Zu Theenhausen HM
- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2015
- Field of study
Results of a search for new phenomena in final states with an energetic jet and large missing transverse momentum are reported. The search uses 20.3 fbâ1 of â s = 8 TeV data collected in 2012 with the ATLAS detector at the LHC. Events are required to have at least one jet with pT > 120 GeV and no leptons. Nine signal regions are considered with increasing missing transverse momentum requirements between Emiss T > 150 GeV and Emiss T > 700 GeV. Good agreement is observed between the number of events in data and Standard Model expectations. The results are translated into exclusion limits on models with either large extra spatial dimensions, pair production of weakly interacting dark matter candidates, or production of very light gravitinos in a gauge-mediated supersymmetric model. In addition, limits on the production of an invisibly decaying Higgs-like boson leading to similar topologies in the final state are presente
Evaluation of Continuous Tumor-Size-Based End Points as Surrogates for Overall Survival in Randomized Clinical Trials in Metastatic Colorectal Cancer
- Author
- Adam R
- Adams R
- Ajani J
- Allegra CJ
- Andre T
- Arnold D
- Bachet J-B
- Benson AB
- Berlin J
- Bleiberg H
- Bodoky G
- Bokemeyer C
- Burzykowski T
- Buyse M
- Buyse M
- Chibaudel B
- Coart E
- de Gramont A
- de Gramont A
- Diaz-Rubio E
- Diaz-Rubio E
- Douillard J-Y
- Douillard J-Y
- Ellis L
- Eng C
- Falcone A
- Falcone A
- Franko J
- Fuchs CS
- Fuchs CS
- Fujii M
- Giantonio BJ
- Goldberg RM
- Goldberg RM
- Grothey A
- Haller D
- Hamilton SR
- Hausner PF
- Hecht JR
- Hecht JR
- Heinemann V
- Herrera A
- Hochster HS
- Hoff PM
- Hoff PM
- Hurwitz H
- Jonker DJ
- Kabbinavar FF
- Kaplan R
- Koeberle D
- Koopman M
- Kopetz S
- Labianca RF
- Larsen AK
- Lenz H-J
- Lieu C
- Loupakis F
- Louvet C
- Marshall J
- Maughan TS
- Maughan TS
- Mayer RJ
- Meropol NJ
- Mitchell EP
- O'Connell MJ
- Peeters M
- Porschen R
- Price T
- Punt CJA
- Punt CJA
- Saad ED
- Salem ME
- Saltz L
- Saltz L
- Schilsky R
- Schmoll H-J
- Schmoll H-J
- Seymour MT
- Seymour MT
- Shi Q
- Shi Q
- Shmueli ES
- Sobrero A
- Sommeijer DW
- Souglakos J
- Tabernero J
- Taieb J
- Tebbutt NC
- Tebbutt NC
- Tejpar S
- Tempero M
- Tournigand C
- Tournigand C
- Tsuji Y
- Van Cutsem E
- Van Cutsem E
- Venook AP
- Weinberg BA
- Wolmark N
- Yoshino T
- Zalcberg JR
- Zalcberg JR
- Publication venue
- AMER MEDICAL ASSOC
- Publication date
- 20/09/2019
- Field of study
IMPORTANCE: Tumor measurements can be used to estimate time to nadir and depth of nadir as potential surrogates for overall survival (OS).
OBJECTIVE: To assess time to nadir and depth of nadir as surrogates for OS in metastatic colorectal cancer.
DESIGN, SETTING, AND PARTICIPANTS: Pooled analysis of 20 randomized clinical trials within the Aide et Recherche en Cancerologie Digestive database, which contains academic and industry-sponsored trials, was conducted. Three sets of comparisons were performed: chemotherapy alone, antiangiogenic agents, and antiâepidermal growth factor receptor agents in first-line treatment for patients with metastatic colorectal cancer.
MAIN OUTCOMES AND MEASURES: Surrogacy of time to nadir and depth of nadir was assessed at the trial level based on joint modeling of relative tumor-size change vs baseline and OS. Treatment effects on time to nadir and on depth of nadir were defined in terms of between-arm differences in time to nadir and in depth of nadir, and both were assessed in linear regressions for their correlation with treatment effects (hazard ratios) on OS within each set. The strengths of association were quantified using sample-sizeâweighted coefficients of determination (R2), with values closer to 1.00 indicating stronger association. At the patient level, the correlation was assessed between modeled relative tumor-size change and OS.
RESULTS: For 14 chemotherapy comparisons in 4289 patients, the R2 value was 0.63 (95% CI, 0.30-0.96) for the association between treatment effects on time to nadir and OS and 0.08 (95% CI, 0-0.37) for depth of nadir and OS. For 11 antiangiogenic agent comparisons (4854 patients), corresponding values of R2 were 0.25 (95% CI, 0-0.72) and 0.06 (95% CI, 0-0.35). For 8 antiâepidermal growth factor receptor comparisons (2684 patients), corresponding values of R2 were 0.24 (95% CI, 0-0.83) and 0.21 (95% CI, 0-0.78).
CONCLUSIONS AND RELEVANCE: In contrast with early reports favoring depth of response as a surrogate, these results suggest that neither time to nadir nor depth of nadir is an acceptable surrogate for OS in the first-line treatment of metastatic colorectal cancer
Future collider signatures of the possible 750 GeV state
- Author
- A Abada
- A Angelescu
- A Angelescu
- A Azatov
- A Barroso
- A Das
- A Denner
- A Djouadi
- A Djouadi
- A Djouadi
- A Djouadi
- A Djouadi
- A Djouadi
- A Djouadi
- A Djouadi
- A Djouadi
- A Djouadi
- A Djouadi
- A Falkowski
- A Falkowski
- A Pilaftsis
- Abdelhak Djouadi
- AD Martin
- BL Combridge
- C Anastasiou
- C Biggio
- C-N Yang
- D Buttazzo
- D Ghosh
- DA Dicus
- DL Borden
- E Kuflik
- F Aguila del
- F Aguila del
- F Aguila del
- F Boudjema
- FF Deppisch
- G Altarelli
- GA Ladinsky
- GC Branco
- GP Lepage
- H Ito
- HE Haber
- HM Georgi
- HM Georgi
- I Chakraborty
- J Babcock
- J Baglio
- J Ellis
- J Kubar-André
- J Steinberger
- JA Aguilar-Saavedra
- JA Aguilar-Saavedra
- JA Oller
- John Ellis
- JR Ellis
- JR Ellis
- JS Bell
- JS Schwinger
- Jérémie Quevillon
- K Kumericki
- L Landau
- L Maiani
- LM Jones
- M Cacciari
- M Carena
- M Chala
- M Gluck
- M Redi
- MR Buckley
- MS Chanowitz
- N Bizot
- N Bizot
- N Craig
- N Toro
- P Bolzoni
- P Mery
- PS Bhupal Dev
- R Foot
- R Franceschini
- R Frederix
- RJ Crewther
- RM Godbole
- RM Godbole
- Rohini Godbole
- RV Harlander
- S Dawson
- S Frixione
- S Gopalakrishna
- S Gopalakrishna
- S Moretti
- SAR Ellis
- SD McDermott
- SL Adler
- SP Martin
- SS Biswal
- T Han
- TG Rizzo
- W BuchmĂŒller
- X-F Han
- Y Mambrini
- Y Okada
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
A constrained supersymmetric left-right model
- Author
- A Falkowski
- A Maloney
- A Maloney
- C Arbelaez
- C ArbelĂĄez
- CF Kolda
- DV Forero
- F Borzumati
- F Staub
- F Staub
- F Staub
- F Staub
- FF Deppisch
- FF Deppisch
- Florian Staub
- H Baer
- J Brehmer
- JA Aguilar-Saavedra
- JE Camargo-Molina
- JE Camargo-Molina
- JH Collins
- JN Esteves
- JN Esteves
- JR Ellis
- K Huitu
- KS Babu
- L Basso
- LE Ibåñez
- M CvetiÄ
- M Drees
- M Goodsell
- M Hirsch
- M Hirsch
- M Papucci
- Manuel E. Krauss
- Martin Hirsch
- MB Einhorn
- MD Goodsell
- ME Krauss
- ME Krauss
- P Batra
- P Langacker
- PS Bhupal Dev
- PS Bhupal Dev
- PSB Dev
- R Kuchimanchi
- S Bertolini
- S Dimopoulos
- SK Majee
- Toby Opferkuch
- U Amaldi
- V Romeri De
- W Porod
- W Porod
- Werner Porod
- WJ Marciano
- Y Zhang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
- âŠ