Profile Of Burn Victims Attended By An Emergency Unit

Objectives: to identify the sociodemographic and health profile of burn victims, knowing the characteristics of the events and detecting the major analgesics prescribed in the emergency department. Methods: descriptive, exploratory and quantitative study with 16 burn victims treated at a Burn Treatment Unit from October 2015 to May 2016. Results: the average age of participants was 31.8 years (± 14.1). Mostly, the subjects were male (62.5%), single (43.8%), brown (68.8%), economically active (75.0%) and coming from Aracaju and its surroundings (62.5%). Injuries from burns were mostly of second degree (93.8%) and reached the lower limbs (68.8%). The average burned body surface was 15.8% (± 11.5). The circumstances surrounding burns occurred mainly at home (50.0%), on Sundays (25.0%) and in the shifts morning (37.5%) and night (37.5%). The main etiological agent was alcohol (31.3%). All patients received analgesia in the emergency department, but the minority had pain documented (18.8%). The physician was the only professional who reported pain in their records, but did incompletely (18.8%). Conclusion: due to the negative effects of burns, it is crucial to adopt educational and preventive measures to change the current scenario of epidemiology of such trauma. Keywords: Burns; Epidemiology; Analgesia; Emergency

Is Music Effective For Pain Relief In Burn Victims?

Objective: to describe the effect of music on pain of burn victims during the dressing change. Methods: applied, descriptive, exploratory and quantitative research held in a Burn Treatment Unit from October 2015 to April 2016. The study included 16 burn victims who were divided in three groups: A: patients heard music before dressing; B: patients hear music during dressing; C: patients did not hear music. Results: the average age was 31.8 years (± 14.1) and most of the subjects were male. Lower limbs and trunk were the most affected parts of the body, especially with second-degree burns and which affected an average of 15.8% (± 11.5) of the body surface. There was a predominance of gospel music (50.0%). The music reduced the average heart rate and oxygen saturation, but did not change ventilatory rate. There was a decrease in the average of pain intensity in groups GB (p = 0.0505 and GC (p = 0.0055). During the dressing, the burning was unanimous characteristic for all subjects, in the same manner as verbal reports was the form of manifestation. Conclusion: music proved to be a simple and effective resource in controlling pain in burn victims. Keywords: Burns; Music; Pain

Doenças tropicais com maior persistência no Amazonas: um olhar retrospectivo de cinco anos

Introdução: As doenças infectocontagiosas são aquelas de fácil e rápida transmissão, provocadas por agentes patogênicos. Objetivo: Descrever as dez doenças infectocontagiosas com maior persistência no Amazonas registradas no hospital de referência entre os anos de 2018 a 2021 enfatizando os possíveis fatores de risco facilitadores da cadeia de transmissão. Delineamento: Estudo retrospectivo, descritivo com abordagem quantitativa. Resultados: foram registradas no período um total de 34.537 doenças infecciosas e parasitarias e outros agravos, destes, 1.472 (4,2%) evoluíram para óbitos. No período foram registrados dois surtos: o primeiro foi o de sarampo em 2018 com 578 casos sem nenhum óbito, o segundo de varíola do macaco (Monkeypox) em 2022 com 107 casos nenhum óbito e uma pandemia causada pelo Corona Vírus (SarCov2) que iniciou no final de 2019 e se estende até a presente data com registro de 2.222 casos somente nesta instituição de saúde com 138 (6,2%) óbitos. Implicações:  Caso não haja medidas efetivas para diminuir a transmissibilidade dessa patologias, a persistência das mesmas pode ter impacto direto no aumento dos gastos públicos e também na qualidade de vida e na produtividade que cada pessoa pode desempenhar no mercado e na sociedade

Educomunicação e suas áreas de intervenção: Novos paradigmas para o diálogo intercultural

oai:omp.abpeducom.org.br:publicationFormat/1O material aqui divulgado representa, em essência, a contribuição do VII Encontro Brasileiro de Educomunicação ao V Global MIL Week, da UNESCO, ocorrido na ECA/USP, entre 3 e 5 de novembro de 2016. Estamos diante de um conjunto de 104 papers executivos, com uma média de entre 7 e 10 páginas, cada um. Com este rico e abundante material, chegamos ao sétimo e-book publicado pela ABPEducom, em seus seis primeiros anos de existência. A especificidade desta obra é a de trazer as “Áreas de Intervenção” do campo da Educomunicação, colocando-as a serviço de uma meta essencial ao agir educomunicativo: o diálogo intercultural, trabalhado na linha do tema geral do evento internacional: Media and Information Literacy: New Paradigms for Intercultural Dialogue

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Accordingly, it is important to update these guidelines for monitoring autophagy in different organisms. Various reviews have described the range of assays that have been used for this purpose. Nevertheless, there continues to be confusion regarding acceptable methods to measure autophagy, especially in multicellular eukaryotes. For example, a key point that needs to be emphasized is that there is a difference between measurements that monitor the numbers or volume of autophagic elements (e.g., autophagosomes or autolysosomes) at any stage of the autophagic process versus those that measure fl ux through the autophagy pathway (i.e., the complete process including the amount and rate of cargo sequestered and degraded). In particular, a block in macroautophagy that results in autophagosome accumulation must be differentiated from stimuli that increase autophagic activity, defi ned as increased autophagy induction coupled with increased delivery to, and degradation within, lysosomes (inmost higher eukaryotes and some protists such as Dictyostelium ) or the vacuole (in plants and fungi). In other words, it is especially important that investigators new to the fi eld understand that the appearance of more autophagosomes does not necessarily equate with more autophagy. In fact, in many cases, autophagosomes accumulate because of a block in trafficking to lysosomes without a concomitant change in autophagosome biogenesis, whereas an increase in autolysosomes may reflect a reduction in degradative activity. It is worth emphasizing here that lysosomal digestion is a stage of autophagy and evaluating its competence is a crucial part of the evaluation of autophagic flux, or complete autophagy. Here, we present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes. These guidelines are not meant to be a formulaic set of rules, because the appropriate assays depend in part on the question being asked and the system being used. In addition, we emphasize that no individual assay is guaranteed to be the most appropriate one in every situation, and we strongly recommend the use of multiple assays to monitor autophagy. Along these lines, because of the potential for pleiotropic effects due to blocking autophagy through genetic manipulation it is imperative to delete or knock down more than one autophagy-related gene. In addition, some individual Atg proteins, or groups of proteins, are involved in other cellular pathways so not all Atg proteins can be used as a specific marker for an autophagic process. In these guidelines, we consider these various methods of assessing autophagy and what information can, or cannot, be obtained from them. Finally, by discussing the merits and limits of particular autophagy assays, we hope to encourage technical innovation in the field