322 research outputs found
Improving the management of an IT department by using a new developed computer application
This work has been developed outside of office hours, in combination with the work of IT Analyst and Project Manager in Philip Morris SA (Switzerland). The dissertation seeks solutions to real-life problems, specifically associated with the daily challenges faced by the managers and team members of the Information Technology department. It was acknowledged the need to enhance the management and assignment of tasks and projects to the team members, where the major issue resided on the understanding of the constraints affecting the work allocation and workload management. To solve the mentioned hurdles, it was needed to develop an appropriate tool, matching the specific needs while being economically efficient and easy to operate. The management was involved in various sharing sessions, allowing the work to be developed in line with the genuine pain-points and to be built accordingly to the needs and expectations of the end-users. The SWOT analysis and the Ishikawa diagram played an important role in the delimitation of the challenges and on documenting the improvement possibilities. Firstly, the problem assessment was done, then it was time to review the literature, searching for the core values and best practices in Project Management. Later, there was an extensive review of the Resources Allocation subject, by concept and objectives, and as a tool to efficiently merging the specificities of the resources and activities while considering an extensive group of constraints. Then, it was done a broad attempt to combine the concepts of the Manager as a human and a servant leader with a focus on team success, with the usage of Resources Allocation tools as indispensable instruments for the success of any Project. Later, the work arrives at its core, with the development of the Allocation Algorithm and the MS Excel® program that allows the Managers to properly register and assign the Projects and Tasks, considering the specificities and constraints in place. The developed tools have been validated and utilized by Managers while performing their daily management routines. The most relevant improvements indicated by the end-users have been, the centralization and availability of the information, the rapidity of new activities’ assignment, and the benefit of having a unified status tool that takes into consideration the team specificities. In the literature, there are different approaches related to the resources’ allocation and project management issues and challenges. However, many of the Researchers never left the concept development stage and several of them have only proposed theoretical approaches. In this work, more than build an algorithm and a program with a straightforward approach to the management challenges, it was prioritized the practicality of the model and the development of a purposeful tool – allowing the ideas to get off paper, implementing the tool and as result, effectively improving the management of activities and the human resources allocation.Este trabalho foi desenvolvido fora do horário de trabalho, em harmonia com o trabalho de Analista IT e Gestor de Projeto na Philip Morris SA (Suíça). Esta dissertação procura encontrar soluções para problemas de gestão, especificamente para os desafios relativos ao trabalho diário dos gestores e membros de equipa do Departamento de Tecnologias da Informação. Assim, foi considerada a necessidade de melhorar o sistema de gestão de tarefas e projetos. Um dos desafios foi compreender as restrições que afetam uma boa gestão e alocação de tarefas, sendo necessário desenvolver uma ferramenta que seja economicamente eficiente e fácil de utilizar. Os gestores foram envolvidos em várias sessões de partilha, permitindo que o trabalho fosse desenvolvido em linha com as necessidades reais e tendo em conta as expetativas dos utilizadores finais da ferramenta. A utilização da análise SWOT e do diagrama de Ishikawa foram muito importantes para delimitar o problema e para definir as oportunidades de melhoria. Primeiramente foi definido o problema, depois foi feita uma revisão da literatura, investigando os valores e os bons princípios da Gestão de Projetos. Seguidamente, foi feita uma revisão sobre a Alocação de Recursos, considerando a base teórica e a aplicabilidade na gestão e alocação de tarefas e de recursos humanos. Paralelamente foi feita uma análise sobre como conjugar o conceito do gestor como humano e líder, e o seu papel no sucesso dos projetos. Foi também analisada a importância das ferramentas na gestão de qualquer projeto. Mais tarde, o trabalho chega ao seu âmago, com o desenvolvimento do Algoritmo de Alocação e do programa MS Excel®, ambos permitindo uma fácil e eficiente alocação de projetos e tarefas por parte dos responsáveis, considerando as restrições e as necessidades da empresa. O desenvolvimento do algoritmo e do programa foi feito em concordância com a gestão, garantindo dessa forma o alinhamento ideal entre o desenvolvimento e as necessidades reais. Os gestores indicaram como benefícios, a forma correta e fácil de associar atividades aos colaboradores, a centralização e qualidade da informação disponibilizada, e ainda a garantia de usar uma ferramenta que considera as especificidades da equipa e os projetos do departamento. Na literatura existem várias abordagens relativas aos desafios da alocação de recursos e da gestão de projetos. Contudo, muitos dos investigadores ficam apenas pela fase do conceito, e muitos apresentam apenas hipóteses e soluções teóricas. Neste trabalho, procurou-se desenvolver um algoritmo e um programa de utilização simples, colocando o funcionalismo e aplicabilidade como prioridades – permitindo que as ideias saíssem do papel, garantindo a implementação da solução e criando melhorias reais em termos de gestão de atividades e gestão de recursos humanos
#080 Alongamento coronário com o uso do laser díodo e sistema piezoelétrico: relato de caso
Introdução: O uso do laser de díodo de alta intensidade em cirurgias periodontais proporciona maior precisão do corte cirúrgico e permite pouca absorção de luz pelos tecidos duros quando se utilizam parâmetros adequados, não gerando assim qualquer dano térmico. Outras vantagens seriam a mais rápida coagulação tecidual, a redução do tempo cirúrgico e a diminuição do risco de infeções pós?operatórias. Outro equipamento com crescente uso é o piezoelétrico, o qual também está indicado em cirurgias orais, a proporcionar também osteotomias mais precisas, limpas e com menor trauma para os tecidos moles. Portanto, o objetivo deste relato foi mostrar a utilização de tecnologias em procedimento estético periodontal. Descrição do caso clínico: Paciente do sexo feminino, 25 anos, saudável, com tratamento ortodôntico prévio, com queixa principal de grande exposição gengival ao sorrir. Planeou?se um alongamento coronário com uso do laser de díodo, em região estética superior (1.4 – 2.4). Após uso do laser para corte gengival, foi feito retalho de espessura total para visualização do osso de sustentação e posterior osteotomia com piezoelétrico, a seguir mensurações e proporções estéticas. Posteriormente, retalho foi reposicionado e suturado. No pós?operatório de 7 dias e 14 dias, pode? se confirmar a excelente recuperação do tecido local e da paciente. Discussão e conclusões: Existem evidências de que a cirurgia em tecidos moles com laser a díodo, e a cirurgia de tecidos duros com aparelho piezoelétrico, proporcionam um bom prognóstico e melhorando assim o pós? cirúrgico do paciente. O laser de díodo permite ter um campo cirúrgico limpo, sem hemorragia, diminuindo o risco de inflamação e infeção pós? cirúrgica quando comparado a sistema tradicional de cirurgias. A osteotomia com piezoeléctrico permite um corte preciso e menos traumático, proporcionando um menor perfil inflamatório a nível ósseo. As vantagens para o paciente são: diminuição da dor e do edema. Enquanto as vantagens para o profissional são: maior sensibilidade tátil e uma melhor visibilidade do campo operatório. Também proporciona proteção dos tecidos moles e das estruturas nobres adjacentes, incluindo um maior controlo da assepsia. A utilização destas tecnologias em cirurgia periodontal mostrou maior exequibilidade e visibilidade, campo cirúrgico mais limpo e menor hemorragia e edema. Inclusive, estas técnicas permitiram reparo ósseo e gengival mais favorável.info:eu-repo/semantics/publishedVersio
Livro Verde dos Montados
O Livro Verde dos Montados apresenta diversos objectivos que se interligam:
Em primeiro lugar, o Livro Verde pretende reunir e sistematizar, de uma forma simples e acessível ao público, o conhecimento produzido em Portugal pelos investigadores e técnicos de várias instituições de investigação ou de gestão que estudam o Montado. Assume-se como uma oportunidade de caracterizar o sistema tendo em conta as suas várias dimensões, identificando as principais ameaças à sua preservação assim como os caminhos que podem ajudar à sua sustentabilidade. Não sendo um documento científico, baseia-se no conhecimento científico e pretende constituir a base para uma plataforma de organização, tanto dos investigadores como do conhecimento científico actualmente produzido em Portugal sobre o Montado.Em segundo lugar, o Livro Verde deverá contribuir para um entendimento partilhado do que é o Montado, por parte do público, de técnicos e de especialistas, conduzindo a uma classificação mais clara do que pode ser considerado Montado e de quais os tipos distintos de Montados que podem ser identificados.
Em terceiro lugar, o Livro Verde estabelece as bases para uma estratégia coordenada de disponibilização de informação sobre o sistema Montado, visando o seu conhecimento, apreciação e valorização pela sociedade portuguesa no seu conjunto. Deste modo, o Livro Verde poderá constituir um instrumento congregador e inspirador para a realização de acções de sensibilização e informação sobre o Montado.
Em quarto lugar, pretende-se que o Livro Verde contribua para um maior reconhecimento e valorização do Montado como sistema, a nível do desenho das políticas nacionais por parte dos vários sectores envolvidos.Finalmente, o Livro Verde constituirá um documento parceiro do Livro Verde das Dehesas, produzido em Espanha em 2010, de forma a reforçar o reconhecimento e a devida valorização destes sistemas silvo-pastoris no desenho das estratégias e políticas relevantes pelas instituições europeias.
Em suma, os autores pretendem que o Livro Verde dos Montados se afirme como o primeiro passo para uma efectiva definição e implementação de uma estratégia nacional para os Montados
Identificação de Problemas e Propostas para Melhoria
authorsversionepub_ahead_of_prin
SARS-CoV-2 introductions and early dynamics of the epidemic in Portugal
Genomic surveillance of SARS-CoV-2 in Portugal was rapidly implemented by
the National Institute of Health in the early stages of the COVID-19 epidemic, in collaboration
with more than 50 laboratories distributed nationwide.
Methods By applying recent phylodynamic models that allow integration of individual-based
travel history, we reconstructed and characterized the spatio-temporal dynamics of SARSCoV-2 introductions and early dissemination in Portugal.
Results We detected at least 277 independent SARS-CoV-2 introductions, mostly from
European countries (namely the United Kingdom, Spain, France, Italy, and Switzerland),
which were consistent with the countries with the highest connectivity with Portugal.
Although most introductions were estimated to have occurred during early March 2020, it is
likely that SARS-CoV-2 was silently circulating in Portugal throughout February, before the
first cases were confirmed.
Conclusions Here we conclude that the earlier implementation of measures could have
minimized the number of introductions and subsequent virus expansion in Portugal. This
study lays the foundation for genomic epidemiology of SARS-CoV-2 in Portugal, and highlights the need for systematic and geographically-representative genomic surveillance.We gratefully acknowledge to Sara Hill and Nuno Faria (University of Oxford) and
Joshua Quick and Nick Loman (University of Birmingham) for kindly providing us with
the initial sets of Artic Network primers for NGS; Rafael Mamede (MRamirez team,
IMM, Lisbon) for developing and sharing a bioinformatics script for sequence curation
(https://github.com/rfm-targa/BioinfUtils); Philippe Lemey (KU Leuven) for providing
guidance on the implementation of the phylodynamic models; Joshua L. Cherry
(National Center for Biotechnology Information, National Library of Medicine, National
Institutes of Health) for providing guidance with the subsampling strategies; and all
authors, originating and submitting laboratories who have contributed genome data on
GISAID (https://www.gisaid.org/) on which part of this research is based. The opinions
expressed in this article are those of the authors and do not reflect the view of the
National Institutes of Health, the Department of Health and Human Services, or the
United States government. This study is co-funded by Fundação para a Ciência e Tecnologia
and Agência de Investigação Clínica e Inovação Biomédica (234_596874175) on
behalf of the Research 4 COVID-19 call. Some infrastructural resources used in this study
come from the GenomePT project (POCI-01-0145-FEDER-022184), supported by
COMPETE 2020 - Operational Programme for Competitiveness and Internationalisation
(POCI), Lisboa Portugal Regional Operational Programme (Lisboa2020), Algarve Portugal
Regional Operational Programme (CRESC Algarve2020), under the PORTUGAL
2020 Partnership Agreement, through the European Regional Development Fund
(ERDF), and by Fundação para a Ciência e a Tecnologia (FCT).info:eu-repo/semantics/publishedVersio
The association between stress and mood across the adult lifespan on default mode network
Aging of brain structure and function is a complex process characterized by high inter- and intra-individual variability. Such variability may arise from the interaction of multiple factors, including exposure to stressful experience and mood variation, across the lifespan. Using a multimodal neuroimaging and neurocognitive approach, we investigated the association of stress, mood and their interaction, in the structure and function of the default mode network (DMN), both during rest and task-induced deactivation, throughout the adult lifespan. Data confirmed a decreased functional connectivity (FC) and task-induced deactivation of the DMN during the aging process and in subjects with lower mood; on the contrary, an increased FC was observed in subjects with higher perceived stress. Surprisingly, the association of aging with DMN was altered by stress and mood in specific regions. An increased difficulty to deactivate the DMN was noted in older participants with lower mood, contrasting with an increased deactivation in individuals presenting high stress, independently of their mood levels, with aging. Interestingly, this constant interaction across aging was globally most significant in the combination of high stress levels with a more depressed mood state, both during resting state and task-induced deactivations. The present results contribute to characterize the spectrum of FC and deactivation patterns of the DMN, highlighting the crucial association of stress and mood levels, during the adult aging process. These combinatorial approaches may help to understand the heterogeneity of the aging process in brain structure and function and several states that may lead to neuropsychiatric disorders.The work was supported by SwitchBox-FP7-HEALTH-2010-Grant 259772-2 and by ON.2, O NOVO NORTE, North Portugal Regional Operational Programme 2007/2013, of the National strategic Reference Framework (NSRF) 2007/2013, through the European Regional Development Fund (ERDF)info:eu-repo/semantics/publishedVersio
Global disparities in surgeons’ workloads, academic engagement and rest periods: the on-calL shIft fOr geNEral SurgeonS (LIONESS) study
: The workload of general surgeons is multifaceted, encompassing not only surgical procedures but also a myriad of other responsibilities. From April to May 2023, we conducted a CHERRIES-compliant internet-based survey analyzing clinical practice, academic engagement, and post-on-call rest. The questionnaire featured six sections with 35 questions. Statistical analysis used Chi-square tests, ANOVA, and logistic regression (SPSS® v. 28). The survey received a total of 1.046 responses (65.4%). Over 78.0% of responders came from Europe, 65.1% came from a general surgery unit; 92.8% of European and 87.5% of North American respondents were involved in research, compared to 71.7% in Africa. Europe led in publishing research studies (6.6 ± 8.6 yearly). Teaching involvement was high in North America (100%) and Africa (91.7%). Surgeons reported an average of 6.7 ± 4.9 on-call shifts per month, with European and North American surgeons experiencing 6.5 ± 4.9 and 7.8 ± 4.1 on-calls monthly, respectively. African surgeons had the highest on-call frequency (8.7 ± 6.1). Post-on-call, only 35.1% of respondents received a day off. Europeans were most likely (40%) to have a day off, while African surgeons were least likely (6.7%). On the adjusted multivariable analysis HDI (Human Development Index) (aOR 1.993) hospital capacity > 400 beds (aOR 2.423), working in a specialty surgery unit (aOR 2.087), and making the on-call in-house (aOR 5.446), significantly predicted the likelihood of having a day off after an on-call shift. Our study revealed critical insights into the disparities in workload, access to research, and professional opportunities for surgeons across different continents, underscored by the HDI
Search for dark matter produced in association with bottom or top quarks in √s = 13 TeV pp collisions with the ATLAS detector
A search for weakly interacting massive particle dark matter produced in association with bottom or top quarks is presented. Final states containing third-generation quarks and miss- ing transverse momentum are considered. The analysis uses 36.1 fb−1 of proton–proton collision data recorded by the ATLAS experiment at √s = 13 TeV in 2015 and 2016. No significant excess of events above the estimated backgrounds is observed. The results are in- terpreted in the framework of simplified models of spin-0 dark-matter mediators. For colour- neutral spin-0 mediators produced in association with top quarks and decaying into a pair of dark-matter particles, mediator masses below 50 GeV are excluded assuming a dark-matter candidate mass of 1 GeV and unitary couplings. For scalar and pseudoscalar mediators produced in association with bottom quarks, the search sets limits on the production cross- section of 300 times the predicted rate for mediators with masses between 10 and 50 GeV and assuming a dark-matter mass of 1 GeV and unitary coupling. Constraints on colour- charged scalar simplified models are also presented. Assuming a dark-matter particle mass of 35 GeV, mediator particles with mass below 1.1 TeV are excluded for couplings yielding a dark-matter relic density consistent with measurements
Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults
Background Underweight and obesity are associated with adverse health outcomes throughout the life course. We
estimated the individual and combined prevalence of underweight or thinness and obesity, and their changes, from
1990 to 2022 for adults and school-aged children and adolescents in 200 countries and territories.
Methods We used data from 3663 population-based studies with 222 million participants that measured height and
weight in representative samples of the general population. We used a Bayesian hierarchical model to estimate
trends in the prevalence of different BMI categories, separately for adults (age ≥20 years) and school-aged children
and adolescents (age 5–19 years), from 1990 to 2022 for 200 countries and territories. For adults, we report the
individual and combined prevalence of underweight (BMI <18·5 kg/m2) and obesity (BMI ≥30 kg/m2). For schoolaged children and adolescents, we report thinness (BMI <2 SD below the median of the WHO growth reference)
and obesity (BMI >2 SD above the median).
Findings From 1990 to 2022, the combined prevalence of underweight and obesity in adults decreased in
11 countries (6%) for women and 17 (9%) for men with a posterior probability of at least 0·80 that the observed
changes were true decreases. The combined prevalence increased in 162 countries (81%) for women and
140 countries (70%) for men with a posterior probability of at least 0·80. In 2022, the combined prevalence of
underweight and obesity was highest in island nations in the Caribbean and Polynesia and Micronesia, and
countries in the Middle East and north Africa. Obesity prevalence was higher than underweight with posterior
probability of at least 0·80 in 177 countries (89%) for women and 145 (73%) for men in 2022, whereas the converse
was true in 16 countries (8%) for women, and 39 (20%) for men. From 1990 to 2022, the combined prevalence of
thinness and obesity decreased among girls in five countries (3%) and among boys in 15 countries (8%) with a
posterior probability of at least 0·80, and increased among girls in 140 countries (70%) and boys in 137 countries (69%)
with a posterior probability of at least 0·80. The countries with highest combined prevalence of thinness and
obesity in school-aged children and adolescents in 2022 were in Polynesia and Micronesia and the Caribbean for
both sexes, and Chile and Qatar for boys. Combined prevalence was also high in some countries in south Asia, such
as India and Pakistan, where thinness remained prevalent despite having declined. In 2022, obesity in school-aged
children and adolescents was more prevalent than thinness with a posterior probability of at least 0·80 among girls
in 133 countries (67%) and boys in 125 countries (63%), whereas the converse was true in 35 countries (18%) and
42 countries (21%), respectively. In almost all countries for both adults and school-aged children and adolescents,
the increases in double burden were driven by increases in obesity, and decreases in double burden by declining
underweight or thinness.
Interpretation The combined burden of underweight and obesity has increased in most countries, driven by an
increase in obesity, while underweight and thinness remain prevalent in south Asia and parts of Africa. A healthy
nutrition transition that enhances access to nutritious foods is needed to address the remaining burden of
underweight while curbing and reversing the increase in obesit
Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries
Abstract
Background
Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres.
Methods
This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries.
Results
In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia.
Conclusion
This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries
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