Evolution of the Ionizing Background at High Redshifts

We use a Maximum-Likelihood analysis to constrain the value and evolution of the ionizing background for 2<z<4.5, taking account of possible systematic errors. (The paper has a more detailed abstract)Comment: 12 figures (9 of those double plots), 17 pages. Accepted by MNRA

The Ursinus Weekly, October 6, 1941

Coulter launches sales campaign for 1942 annual • Enrollment here drops fifty below last year\u27s peak • Adams speaks at first Y vespers; Kooker sings solo • President McClure depicts the role Ursinus can play in defense • Dr. J. L. Barnard passes away after sudden illness • Booster comm. plans Pete Stevens\u27 day and a pep rally Friday • Ursinus offers varied courses in night school for workers in defense • Four attend debate conclave to formulate questions for debate • Terrorized freshman redcaps survive rigors of initial week • Grizzly Gridder due Friday; features Pete Stevens\u27 Day • Ursinus committee wins national prize for essay on The next decade of American foreign policy • Over 750 delegates attend seven summer conferences • Frosh find handbook a directory to campus • Twelve from Ursinus attend June conference at Eagles Mere • Faculty changes made; new prof in physics • Mertz represents Ursinus • Red Devils conquer Stevens\u27 bears in opener by 20-7: Rookie Rehor\u27s passing downs bears Saturday • Forecaster sees good percentage of bear victories • Owls drub bear soccermen 12-0 in game Saturday • Miss Snell drills veteran squad for full schedule • New football coach more than mere grid mentor • Steinmetz to coach Jr. varsity football squad • Ex-Ursinus \u2742, Dick Dennis, lets bride marry best manhttps://digitalcommons.ursinus.edu/weekly/1764/thumbnail.jp

The Ursinus Weekly, June 3, 1940

Directors meet; make Hartzell associate prof. • Reifsnyder takes graduation honors • Week-end addresses consider American democracy\u27s needs • Ursinus crashes Life! • Rev. Dallus Krebs \u2702 elected alumni head • Meistersingers, choir have annual sacred music concert • Encore for Outward bound to be staged at Royersford • Initiations and banquet mark 15th anniversary of TKA • Eighteen from Ursinus will go to Eaglesmere • Women\u27s Club admits 72 at business meeting on Friday • Louise Joulia stars in The Firefly production • Lantern contains works of three seniors • Racqueteers lose three senior stars • Fred Swift chosen by baseball squad • \u27Ed\u27 Conine proves bear high scorer • Short season in women\u27s golf produces single win and loss • Jingmen\u27s record shows ratio of six wins in ten games • Batting averages of baseball sluggers • Jayvees finish poor season with one win, four defeats • Men\u27s tennis team hands in score of one win in four • Dr. W. H. Stoner discusses hormones and endocrinologyhttps://digitalcommons.ursinus.edu/weekly/1845/thumbnail.jp

The Ursinus Weekly, April 28, 1941

Causes of cancer told to pre-meds by Pfahler • Manchester to sub for Wallace May 6 • Besse Howard will speak at forum Wednesday on topic, Spring, 1941 • Sub-frosh to view Ursinus this Saturday • May hop to feature music of Woody Leh • \u27Unity in diversity\u27 will be conference theme on May 7 • The Ursinus weekend travelogue around the circuit • Play \u27Lightnin\u27 centers around Calivada Hotel • Sixteen visit medical centers on excursion to New York • Five attend chemistry conference at Villanova • Powers of God are subject of vespers • Herber is pre-legal prexy • Meistersingers plan spring concert, May 1 • French Club to hear talk on prestige of French tongue • Debaters elect Lownes prexy; mixed team meets Drexel • Kriebel, Hartman to present reviews of Hilton and Brittain • Class of 1940 makes the grade in business and graduate work • IRC elects Byron president; discusses plans for next year • Local draft boards to weigh claims of students for deferment • Baseballers lose to Mules 3-2; trounce Dickinson 12-2 • Irvin paces track squad to victory over Delaware clan by 65-61 score • Netmen blank Lions in season opener • Co-ed net squad defeats Penn and Albright lassies • Zulick and Baberick win as Moravian beats golfers 3-2 • Freshman girls lead race in class softball league • Doc Baker heads old English game at Ursinus • Carter\u27s articles appear in historical dictionary • Hobos and bums to have poverty ball Saturday • Y officers to be inducted in service on Sundayhttps://digitalcommons.ursinus.edu/weekly/1816/thumbnail.jp

Patient, health service factors and variation in mortality following resuscitated out-of-hospital cardiac arrest in acute coronary syndrome : analysis of the Myocardial Ischaemia National Audit Project

Aims To determine patient and health service factors associated with variation in hospital mortality among resuscitated cases of out-of-hospital cardiac arrest (OHCA) with acute coronary syndrome (ACS). Methods In this cohort study, we used the Myocardial Ischaemia National Audit Project database to study outcomes in patients hospitalised with resuscitated OHCA due to ACS between 2003 and 2015 in the United Kingdom. We analysed variation in inter-hospital mortality and used hierarchical multivariable regression models to examine the association between patient and health service factors with hospital mortality. Results We included 17604 patients across 239 hospitals. Overall hospital mortality was 28.7%. In 94 hospitals that contributed at least 60 cases, mortality by hospital ranged from 10.7% to 66.3% (median 28.6%, IQR 23.2% to 39.1%)). Patient and health service factors explained 36.1% of this variation. After adjustment for covariates, factors associated with higher hospital mortality included increasing serum glucose, ST-Elevation myocardial infarction (STEMI) diagnosis, and initial admission to a primary percutaneous coronary intervention (pPCI) capable hospital. Hospital OHCA volume was not associated with mortality. The key modifiable factor associated with lower mortality was early reperfusion therapy in STEMI patients. Conclusion There was wide variation in inter-hospital mortality following resuscitated OHCA due to ACS that was only partially explained by patient and health service factors. Hospital OHCA volume and pPCI capability were not associated with lower mortality. Early reperfusion therapy was associated with lower mortality in STEMI patients

Variation in outcome of hospitalised patients with out-of-hospital cardiac arrest from acute coronary syndrome : a cohort study

Background Each year, approximately 30,000 people have an out-of-hospital cardiac arrest (OHCA) that is treated by UK ambulance services. Across all cases of OHCA, survival to hospital discharge is less than 10%. Acute coronary syndrome (ACS) is a common cause of OHCA. Objectives To explore factors that influence survival in patients who initially survive an OHCA attributable to ACS. Data source Data collected by the Myocardial Ischaemia National Audit Project (MINAP) between 2003 and 2015. Participants Adult patients who had a first OHCA attributable to ACS and who were successfully resuscitated and admitted to hospital. Main outcome measures Hospital mortality, neurological outcome at hospital discharge, and time to all-cause mortality. Methods We undertook a cohort study using data from the MINAP registry. MINAP is a national audit that collects data on patients admitted to English, Welsh and Northern Irish hospitals with myocardial ischaemia. From the data set, we identified patients who had an OHCA. We used imputation to address data missingness across the data set. We analysed data using multilevel logistic regression to identify modifiable and non-modifiable factors that affect outcome. Results Between 2003 and 2015, 1,127,140 patient cases were included in the MINAP data set. Of these, 17,604 OHCA cases met the study inclusion criteria. Overall hospital survival was 71.3%. Across hospitals with at least 60 cases, hospital survival ranged from 34% to 89% (median 71.4%, interquartile range 60.7–76.9%). Modelling, which adjusted for patient and treatment characteristics, could account for only 36.1% of this variability. For the primary outcome, the key modifiable factors associated with reduced mortality were reperfusion treatment [primary percutaneous coronary intervention (pPCI) or thrombolysis] and admission under a cardiologist. Admission to a high-volume cardiac arrest hospital did not influence survival. Sensitivity analyses showed that reperfusion was associated with reduced mortality among patients with a ST elevation myocardial infarction (STEMI), but there was no evidence of a reduction in mortality in patients who did not present with a STEMI. Limitations This was an observational study, such that unmeasured confounders may have influenced study findings. Differences in case identification processes at hospitals may contribute to an ascertainment bias. Conclusions In OHCA patients who have had a cardiac arrest attributable to ACS, there is evidence of variability in survival between hospitals, which cannot be fully explained by variables captured in the MINAP data set. Our findings provide some support for the current practice of transferring resuscitated patients with a STEMI to a hospital that can deliver pPCI. In contrast, it may be reasonable to transfer patients without a STEMI to the nearest appropriate hospital. Future work There is a need for clinical trials to examine the clinical effectiveness and cost-effectiveness of invasive reperfusion strategies in resuscitated OHCA patients of cardiac cause who have not had a STEMI. Funding The National Institute for Health Research Health Services and Delivery Research programme

Adaptation or conflict? Responses to climate change in water management in Bangladesh

The potential of climate change to impact local conflict and cooperation over natural resources has received relatively little attention. Bangladesh floodplains are highly vulnerable to environmental stresses that are worsening with climate change, and community organisations have to respond to water insecurity − seasonally too little or too much. Two case studies based on action research in contrasting water and climate stressed floodplain environments in Bangladesh investigate local conflicts over water management that worsened when water regimes changed. By overcoming conflicts and improving adaptation for all local actors the cases reveal the importance of local knowledge, innovations in institutions, external facilitation, and incentives provided by disadvantaged groups who contribute towards costs in return for a share in decision making power and better adapted water management. The cases show how community organisations diversified their responsibilities and took up the challenge of water management to address local priorities and overcome conflicts. Without a more flexible and enabling approach, public investments in adaptation are likely to focus on strengthening existing water management infrastructure without understanding local social interactions and complexity. This may strengthen elite dominance and local conflicts if there is no comparable investment in developing robust and fair local institutions

Social impacts as a function of place change

This paper argues that both impacts felt by and attitudes to tourism are a function of place change. Destinations are comprised of three types of place: tourism, non-tourism and shared. It is believed attitudes are generally positive when stasis exists among the three types, but deteriorate during periods of rapid place change. Likewise, impacts are felt when place changes, especially when non-tourism place is transformed into either shared or tourism place. This proposition is tested through a meta-analysis of more than 90 journal articles examining social impacts of tourism. Nine types of place change were identified as well as a relationship between place change and lifecycle stage

Multi-messenger observations of a binary neutron star merger

On 2017 August 17 a binary neutron star coalescence candidate (later designated GW170817) with merger time 12:41:04 UTC was observed through gravitational waves by the Advanced LIGO and Advanced Virgo detectors. The Fermi Gamma-ray Burst Monitor independently detected a gamma-ray burst (GRB 170817A) with a time delay of ~1.7 s with respect to the merger time. From the gravitational-wave signal, the source was initially localized to a sky region of 31 deg2 at a luminosity distance of 40+8-8 Mpc and with component masses consistent with neutron stars. The component masses were later measured to be in the range 0.86 to 2.26 Mo. An extensive observing campaign was launched across the electromagnetic spectrum leading to the discovery of a bright optical transient (SSS17a, now with the IAU identification of AT 2017gfo) in NGC 4993 (at ~40 Mpc) less than 11 hours after the merger by the One- Meter, Two Hemisphere (1M2H) team using the 1 m Swope Telescope. The optical transient was independently detected by multiple teams within an hour. Subsequent observations targeted the object and its environment. Early ultraviolet observations revealed a blue transient that faded within 48 hours. Optical and infrared observations showed a redward evolution over ~10 days. Following early non-detections, X-ray and radio emission were discovered at the transient’s position ~9 and ~16 days, respectively, after the merger. Both the X-ray and radio emission likely arise from a physical process that is distinct from the one that generates the UV/optical/near-infrared emission. No ultra-high-energy gamma-rays and no neutrino candidates consistent with the source were found in follow-up searches. These observations support the hypothesis that GW170817 was produced by the merger of two neutron stars in NGC4993 followed by a short gamma-ray burst (GRB 170817A) and a kilonova/macronova powered by the radioactive decay of r-process nuclei synthesized in the ejecta