The Manipulation of Visual and Aural Allegorical Images on Motion Picture Film

As a means of expression and communication, I have found motion picture film to be the most rewarding arid satisfying artistic medium I have yet encountered with the exception of musical sounds. Because I feel a strong affinity for both film and music on a nearly equal basis, and because the two art forms compliment each other in practical and aesthetic senses, I have attempted to develop from established film theories, a personal and therefore unique approach to the combination of sound and picture images and the statement held therein

Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk

We performed a meta-analysis of five genome-wide association studies to identify common variants influencing colorectal cancer (CRC) risk comprising 8,682 cases and 9,649 controls. Replication analysis was performed in case-control sets totaling 21,096 cases and 19,555 controls. We identified three new CRC risk loci at 6p21 (rs1321311, near CDKN1A; P = 1.14 × 10 -10), 11q13.4 (rs3824999, intronic to POLD3; P = 3.65 × 10 -10) and Xp22.2 (rs5934683, near SHROOM2; P = 7.30 × 10 -10) This brings the number of independent loci associated with CRC risk to 20 and provides further insight into the genetic architecture of inherited susceptibility to CRC.</p