Abiotic Stress Management in Vegetable Crops

Vegetables are highly sensitive in nature thus affected by various biotic and abiotic stress. Any adverse effect of non-living elements on living things in a particular habitat is known as abiotic stress. The production and productivity of vegetable crops got highly effected by the extreme event of climate change i.e, heat stress, water stress, drought, heavy rainfall, salinity etc. Vegetables are full of various nutrients which help in lowering the risk of various diseases such as cancer, heart disease, blood pressure, diabetes etc. Most of the vegetables contain more than 90% of water thus highly sensitive to climate change. Sudden change in climatic factors like in temperature affects all stages of plant growth, pollination, flowering and fruiting which directly reduces the yields and quality of major vegetables. Vegetable crops like beans or tomatoes may lose some of their blossoms at such high temperatures, especially in dry or windy conditions, which will lead to a poor fruit set. High temperatures may harm sweet corn pollination and result in inadequately filled ears of corn. Few fruits are produced because cucurbits (the family that includes pumpkins and squash) typically develop mostly male flowers when temperatures are high

Clinical Evaluation of Serum Alpha Feto-Protein (AFP) and Interlukin-6 in Hepatocellular Carcinoma

Background: Hepatocellular carcinoma (HCC) is one of the important cancers worldwide and predominant in Asia and Africa. A number of evidence suggests a possible role of interleukin-6 (IL-6) and α-Fetoprotein (AFP) in the pathogenesis of hepatocellular carcinoma (HCC).Patients and methods: We studied both IL-6 and AFP in patients with HCC or in healthy controls. Serum IL-6, AFP was measured by enzyme linked immunosorbent assay and Chemiluminescent immunoassay respectively in 30 patients with primary hepatocellular carcinoma and 30 normal subjectsResults:IL-6 and AFP was found in high levels in the serum of patients initially diagnosed with HCC (18±9.8), and (315.99±594.62) respectively compared with healthy subjects (4.29±2.10).and (3.13±1.27).A significant positive correlation was found between mean levels of IL- 6 & AFP in HCC (P < 0.05), Combination of IL-6 and AFP improved the sensitivity in diagnosing HCC or predicting future HCC development. Conclusions: IL-6 along with AFP could be considered a promising tumor marker for HCC. In particular, the diagnostic value of the test is significantly increased when combined with AFP

Identification of new donors for spot blotch resistance in cultivated wheat germplasm

One thousand four hundred and eighty three spring wheat germplasm (Triticum aestivum L.) lines comprising Indian as well as exotic lines were screened for resistance to spot blotch disease during winter 2014-15 at hot spot locations i.e., Banaras Hindu University, Varanasi and Uttar Banga Krishi Vishwavidyalaya, Cooch Behar. Severity of the disease at different stages beginning from tillering to dough stage was recorded. Location Severity Index (LSI) of Varanasi was higher than Cooch Behar. Twenty eight accessions were resistant or highly resistant at both locations. These 28 accessions were validated during the winter season (2015–2016). These germplasm were also evaluated at four environments for agronomic traits. Out of 28 accessions, seven (IC564121, IC529684, IC443669, IC443652, IC529962, IC548325 and EC178071-331) were highly resistant across the locations and over the years of study. These accessions comprised one exotic and six indigenous accessions belonging to Uttarakhand and Haryana. Two lines (IC529962 and IC443652) had higher yield than the best check at all the locations. These lines showing highly resistant reaction alongwith wider adaptability can be expedited for direct cultivation or for the development of high yielding and disease resistant cultivars. These lines can also be used for identification of novel resistance gene using allele mining tools and their deployment for the development of spot blotch resistant cultivars

Meta-analysis of exome array data identifies six novel genetic loci for lung function

Background: Over 90 regions of the genome have been associated with lung function to date, many of which have also been implicated in chronic obstructive pulmonary disease. Methods: We carried out meta-analyses of exome array data and three lung function measures: forced expiratory volume in one second (FEV1), forced vital capacity (FVC) and the ratio of FEV1 to FVC (FEV1/FVC). These analyses by the SpiroMeta and CHARGE consortia included 60,749 individuals of European ancestry from 23 studies, and 7,721 individuals of African Ancestry from 5 studies in the discovery stage, with follow-up in up to 111,556 independent individuals. Results: We identified significant (P<2·8x10-7) associations with six SNPs: a nonsynonymous variant in RPAP1, which is predicted to be damaging, three intronic SNPs (SEC24C, CASC17 and UQCC1) and two intergenic SNPs near to LY86 and FGF10. Expression quantitative trait loci analyses found evidence for regulation of gene expression at three signals and implicated several genes, including TYRO3 and PLAU. Conclusions: Further interrogation of these loci could provide greater understanding of the determinants of lung function and pulmonary disease

Measurements of differential production cross sections for a Z boson in association with jets in pp collisions at root s=8 TeV

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Search for leptophobic Z ' bosons decaying into four-lepton final states in proton-proton collisions at root s=8 TeV

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Search for black holes and other new phenomena in high-multiplicity final states in proton-proton collisions at root s=13 TeV

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Search for heavy resonances decaying into a vector boson and a Higgs boson in final states with charged leptons, neutrinos, and b quarks

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