Evidence for Reduced Specific Star Formation Rates in the Centers of Massive Galaxies at z = 4

We perform the first spatially-resolved stellar population study of galaxies in the early universe (z = 3.5 - 6.5), utilizing the Hubble Space Telescope Cosmic Assembly Near-infrared Deep Extragalactic Legacy Survey (CANDELS) imaging dataset over the GOODS-S field. We select a sample of 418 bright and extended galaxies at z = 3.5 - 6.5 from a parent sample of ~ 8000 photometric-redshift selected galaxies from Finkelstein et al. (2015). We first examine galaxies at 3.5< z < 4.0 using additional deep K-band survey data from the HAWK-I UDS and GOODS Survey (HUGS) which covers the 4000A break at these redshifts. We measure the stellar mass, star formation rate, and dust extinction for galaxy inner and outer regions via spatially-resolved spectral energy distribution fitting based on a Markov Chain Monte Carlo algorithm. By comparing specific star formation rates (sSFRs) between inner and outer parts of the galaxies we find that the majority of galaxies with the high central mass densities show evidence for a preferentially lower sSFR in their centers than in their outer regions, indicative of reduced sSFRs in their central regions. We also study galaxies at z ~ 5 and 6 (here limited to high spatial resolution in the rest-frame ultraviolet only), finding that they show sSFRs which are generally independent of radial distance from the center of the galaxies. This indicates that stars are formed uniformly at all radii in massive galaxies at z ~ 5 - 6, contrary to massive galaxies at z < 4.Comment: Accepted to ApJ, 20 pages, 15 figure

JWST NIRSpec Spectroscopy of the Triply Lensed z = 10.17 Galaxy MACS0647–JD

We present JWST/NIRSpec prism spectroscopy of MACS0647‑JD, a triply lensed z ∼ 11 candidate discovered in Hubble Space Telescope imaging and spatially resolved by JWST imaging into two components, A and B. Spectroscopy of component A yields a spectroscopic redshift z = 10.17 based on seven detected emission lines: C III] λ λ1907, 1909, [O II] λ3727, [Ne III] λ3869, [Ne III] λ3968, Hδ λ4101, Hγ λ4340, and [O III] λ4363. These are the second-most distant detections of these emission lines to date, in a galaxy observed just 460 million years after the Big Bang. Based on observed and extrapolated line flux ratios we derive a gas-phase metallicity 12 + log(O/H) ∼ 7.5–8.0, or Z ∼ (0.06–0.2) Z ⊙, ionization parameter log(U) = ‑1.9 ± 0.2, and an ionizing photon production efficiency log(ξion)=25.2±0.2 erg‑1 Hz. The spectrum has a softened Lyα break, evidence for a strong Lyα damping wing. The Lyα damping wing also suppresses the F150W photometry, explaining the slightly overestimated photometric redshift z = 10.6 ± 0.3. MACS0647‑JD has a stellar mass log(M/M ⊙) = 8.1 ± 0.3, including ∼6 × 107 M ⊙ in component A, most of which formed recently (within ∼20 Myr) with a star formation rate ∼ 2 ± 1 M ⊙ yr‑1, all within an effective radius 70 ± 24 pc. Spectroscopy of a fainter companion galaxy C separated by a distance of ∼ 3 kpc reveals a Lyman break consistent with z ∼ 10.17. MACS0647‑JD is likely the most distant galaxy merger known

Severe early onset preeclampsia: short and long term clinical, psychosocial and biochemical aspects

Preeclampsia is a pregnancy specific disorder commonly defined as de novo hypertension and proteinuria after 20 weeks gestational age. It occurs in approximately 3-5% of pregnancies and it is still a major cause of both foetal and maternal morbidity and mortality worldwide1. As extensive research has not yet elucidated the aetiology of preeclampsia, there are no rational preventive or therapeutic interventions available. The only rational treatment is delivery, which benefits the mother but is not in the interest of the foetus, if remote from term. Early onset preeclampsia (<32 weeks’ gestational age) occurs in less than 1% of pregnancies. It is, however often associated with maternal morbidity as the risk of progression to severe maternal disease is inversely related with gestational age at onset2. Resulting prematurity is therefore the main cause of neonatal mortality and morbidity in patients with severe preeclampsia3. Although the discussion is ongoing, perinatal survival is suggested to be increased in patients with preterm preeclampsia by expectant, non-interventional management. This temporising treatment option to lengthen pregnancy includes the use of antihypertensive medication to control hypertension, magnesium sulphate to prevent eclampsia and corticosteroids to enhance foetal lung maturity4. With optimal maternal haemodynamic status and reassuring foetal condition this results on average in an extension of 2 weeks. Prolongation of these pregnancies is a great challenge for clinicians to balance between potential maternal risks on one the eve hand and possible foetal benefits on the other. Clinical controversies regarding prolongation of preterm preeclamptic pregnancies still exist – also taking into account that preeclampsia is the leading cause of maternal mortality in the Netherlands5 - a debate which is even more pronounced in very preterm pregnancies with questionable foetal viability6-9. Do maternal risks of prolongation of these very early pregnancies outweigh the chances of neonatal survival? Counselling of women with very early onset preeclampsia not only comprises of knowledge of the outcome of those particular pregnancies, but also knowledge of outcomes of future pregnancies of these women is of major clinical importance. This thesis opens with a review of the literature on identifiable risk factors of preeclampsia

Impacts of the Tropical Pacific/Indian Oceans on the Seasonal Cycle of the West African Monsoon

The current consensus is that drought has developed in the Sahel during the second half of the twentieth century as a result of remote effects of oceanic anomalies amplified by local land–atmosphere interactions. This paper focuses on the impacts of oceanic anomalies upon West African climate and specifically aims to identify those from SST anomalies in the Pacific/Indian Oceans during spring and summer seasons, when they were significant. Idealized sensitivity experiments are performed with four atmospheric general circulation models (AGCMs). The prescribed SST patterns used in the AGCMs are based on the leading mode of covariability between SST anomalies over the Pacific/Indian Oceans and summer rainfall over West Africa. The results show that such oceanic anomalies in the Pacific/Indian Ocean lead to a northward shift of an anomalous dry belt from the Gulf of Guinea to the Sahel as the season advances. In the Sahel, the magnitude of rainfall anomalies is comparable to that obtained by other authors using SST anomalies confined to the proximity of the Atlantic Ocean. The mechanism connecting the Pacific/Indian SST anomalies with West African rainfall has a strong seasonal cycle. In spring (May and June), anomalous subsidence develops over both the Maritime Continent and the equatorial Atlantic in response to the enhanced equatorial heating. Precipitation increases over continental West Africa in association with stronger zonal convergence of moisture. In addition, precipitation decreases over the Gulf of Guinea. During the monsoon peak (July and August), the SST anomalies move westward over the equatorial Pacific and the two regions where subsidence occurred earlier in the seasons merge over West Africa. The monsoon weakens and rainfall decreases over the Sahel, especially in August.Peer reviewe

Penilaian Kinerja Keuangan Koperasi di Kabupaten Pelalawan

This paper describe development and financial performance of cooperative in District Pelalawan among 2007 - 2008. Studies on primary and secondary cooperative in 12 sub-districts. Method in this stady use performance measuring of productivity, efficiency, growth, liquidity, and solvability of cooperative. Productivity of cooperative in Pelalawan was highly but efficiency still low. Profit and income were highly, even liquidity of cooperative very high, and solvability was good

Measurements of the pp → ZZ production cross section and the Z → 4ℓ branching fraction, and constraints on anomalous triple gauge couplings at √s = 13 TeV

Four-lepton production in proton-proton collisions, pp -> (Z/gamma*)(Z/gamma*) -> 4l, where l = e or mu, is studied at a center-of-mass energy of 13 TeV with the CMS detector at the LHC. The data sample corresponds to an integrated luminosity of 35.9 fb(-1). The ZZ production cross section, sigma(pp -> ZZ) = 17.2 +/- 0.5 (stat) +/- 0.7 (syst) +/- 0.4 (theo) +/- 0.4 (lumi) pb, measured using events with two opposite-sign, same-flavor lepton pairs produced in the mass region 60 4l) = 4.83(-0.22)(+0.23) (stat)(-0.29)(+0.32) (syst) +/- 0.08 (theo) +/- 0.12(lumi) x 10(-6) for events with a four-lepton invariant mass in the range 80 4GeV for all opposite-sign, same-flavor lepton pairs. The results agree with standard model predictions. The invariant mass distribution of the four-lepton system is used to set limits on anomalous ZZZ and ZZ. couplings at 95% confidence level: -0.0012 < f(4)(Z) < 0.0010, -0.0010 < f(5)(Z) < 0.0013, -0.0012 < f(4)(gamma) < 0.0013, -0.0012 < f(5)(gamma) < 0.0013

Optimasi Portofolio Resiko Menggunakan Model Markowitz MVO Dikaitkan dengan Keterbatasan Manusia dalam Memprediksi Masa Depan dalam Perspektif Al-Qur`an

Risk portfolio on modern finance has become increasingly technical, requiring the use of sophisticated mathematical tools in both research and practice. Since companies cannot insure themselves completely against risk, as human incompetence in predicting the future precisely that written in Al-Quran surah Luqman verse 34, they have to manage it to yield an optimal portfolio. The objective here is to minimize the variance among all portfolios, or alternatively, to maximize expected return among all portfolios that has at least a certain expected return. Furthermore, this study focuses on optimizing risk portfolio so called Markowitz MVO (Mean-Variance Optimization). Some theoretical frameworks for analysis are arithmetic mean, geometric mean, variance, covariance, linear programming, and quadratic programming. Moreover, finding a minimum variance portfolio produces a convex quadratic programming, that is minimizing the objective function ðð¥with constraintsð ð 𥠥 ðandð´ð¥ = ð. The outcome of this research is the solution of optimal risk portofolio in some investments that could be finished smoothly using MATLAB R2007b software together with its graphic analysis

Search for heavy resonances decaying to two Higgs bosons in final states containing four b quarks

A search is presented for narrow heavy resonances X decaying into pairs of Higgs bosons (H) in proton-proton collisions collected by the CMS experiment at the LHC at root s = 8 TeV. The data correspond to an integrated luminosity of 19.7 fb(-1). The search considers HH resonances with masses between 1 and 3 TeV, having final states of two b quark pairs. Each Higgs boson is produced with large momentum, and the hadronization products of the pair of b quarks can usually be reconstructed as single large jets. The background from multijet and t (t) over bar events is significantly reduced by applying requirements related to the flavor of the jet, its mass, and its substructure. The signal would be identified as a peak on top of the dijet invariant mass spectrum of the remaining background events. No evidence is observed for such a signal. Upper limits obtained at 95 confidence level for the product of the production cross section and branching fraction sigma(gg -> X) B(X -> HH -> b (b) over barb (b) over bar) range from 10 to 1.5 fb for the mass of X from 1.15 to 2.0 TeV, significantly extending previous searches. For a warped extra dimension theory with amass scale Lambda(R) = 1 TeV, the data exclude radion scalar masses between 1.15 and 1.55 TeV

Extreme damped Lyman-α\alpha absorption in young star-forming galaxies at z=9−11z=9-11

The onset of galaxy formation is thought to be initiated by the infall of neutral, pristine gas onto the first protogalactic halos. However, direct constraints on the abundance of neutral atomic hydrogen (HI) in galaxies have been difficult to obtain at early cosmic times. Here we present spectroscopic observations with JWST of three galaxies at redshifts $z=8.8 - 11.4$, about $400-600$ Myr after the Big Bang, that show strong damped Lyman-$\alpha$ absorption ($N_{\rm HI} > 10^{22}$ cm$^{-2}$) from HI in their local surroundings, an order of magnitude in excess of the Lyman-$\alpha$ absorption caused by the neutral intergalactic medium at these redshifts. Consequently, these early galaxies cannot be contributing significantly to reionization, at least at their current evolutionary stages. Simulations of galaxy formation show that such massive gas reservoirs surrounding young galaxies so early in the history of the universe is a signature of galaxy formation in progress.Comment: Submitte

JWST Reveals a Possible z ∼ 11 Galaxy Merger in Triply Lensed MACS0647-JD

MACS0647–JD is a triply lensed z ∼ 11 galaxy originally discovered with the Hubble Space Telescope. The three lensed images are magnified by factors of ∼8, 5, and 2 to AB mag 25.1, 25.6, and 26.6 at 3.5 μm. The brightest is over a magnitude brighter than other galaxies recently discovered at similar redshifts z > 10 with JWST. Here, we report new JWST imaging that clearly resolves MACS0647–JD as having two components that are either merging galaxies or stellar complexes within a single galaxy. The brighter larger component “A” is intrinsically very blue (β ∼ −2.6 ± 0.1), likely due to very recent star formation and no dust, and is spatially extended with an effective radius ∼70 ± 24 pc. The smaller component “B” (r ∼ 20-+58 pc) appears redder (β ∼ −2 ± 0.2), likely because it is older (100–200 Myr) with mild dust extinction (AV ∼ 0.1 mag). With an estimated stellar mass ratio of roughly 2:1 and physical projected separation ∼400 pc, we may be witnessing a galaxy merger 430 million years after the Big Bang. We identify galaxies with similar colors in a high-redshift simulation, finding their star formation histories to be dissimilar, which is also suggested by the spectral energy distribution fitting, suggesting they formed further apart. We also identify a candidate companion galaxy “C” ∼3 kpc away, likely destined to merge with A and B. Upcoming JWST Near Infrared Spectrograph observations planned for 2023 January will deliver spectroscopic redshifts and more physical properties for these tiny magnified distant galaxies observed in the early universe.We are grateful and indebted to all 20,000 people who worked to make JWST an incredible discovery machine. We dedicate these JWST observations to Rob Hawkins, former lead developer of the Astronomer’s Proposal Tool (APT). Rob lost his life in 2020 November while astronomers around the world were using APT to prepare observations we proposed for JWST Cycle 1. This work is based on observations made with the NASA/ESA/CSA James Webb Space Telescope (JWST) and Hubble Space Telescope (HST). The data were obtained from theMikulski Archive for Space Telescopes (MAST) at the Space Telescope Science Institute (STScI), which is operated by the Association of Universities for Research in Astronomy (AURA), Inc., under NASA contract NAS 5-03127 for JWST. These observations are associated with programs JWST-GO1433 and HST-GO 9722, 10493, 10793, and 12101. T.H. and A. were funded by a grant for JWST-GO-01433 provided by STScI under NASA contract NAS 5-03127. L.W. acknowledges support from the National Science Foundation Graduate Research Fellowship under grant No. DGE-2137419. A.A. acknowledges support from the Swedish Research Council (Vetenskapsrådet project grant No. 2021-05559). P. D. acknowledges support from the NWO grant 016. VIDI.189.162 (“ODIN”) and the European Commission’s and University of Groningen’s CO-FUND Rosalind Franklin program and warmly thanks the Institute for Advanced Study (IAS) Princeton, where a part of this work was carried out, for their generous hospitality and support through the Bershadsky Fund. The Cosmic Dawn Center is funded by the Danish National Research Foundation (DNRF) under grant #140. E.Z. and A.V. ackowledge support from the Swedish National Space Agency. M.B. acknowledges support from the Slovenian national research agency ARRS through grant No. N1-0238. M.O. acknowledges support from JSPS KAKENHI grant Nos. JP22H01260, JP20H05856, JP20H00181, and JP22K21349. A. Z., A.K.M., and L.J.F. acknowledge support by grant No. 2020750 from the United States-Israel Binational Science Foundation (BSF) and grant No. 2109066 from the United States National Science Foundation (NSF), and by the Ministry of Science & Technology, Israel. E.V. and M.N. acknowledge financial support through grant Nos. PRIN-MIUR 2017WSCC32 and 2020SKSTHZ and INAF “main-stream” grant Nos. 1.05.01.86.20 and 1.05.01.86.31. Y.J.-T. acknowl edges financial support from the European Union’s Horizon 2020 research and innovation program under the Marie Sklodowska-Curie grant agreement No. 898633, the MSCA IF Extensions Program of the Spanish National Research Council (CSIC), and the State Agency for Research of the Spanish MCIU through the Center of Excellence Severo Ochoa award to the Instituto de Astrofísica de Andalucía (SEV-2017- 0709). A.C.C. thanks the Leverhulme Trust for their support via a Leverhulme Early Career Fellowshi