4,251 research outputs found

    Plataforma per a agrupacions de comerços locals

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    Treballs Finals de Grau d'Enginyeria Informàtica, Facultat de Matemàtiques, Universitat de Barcelona, Any: 2019, Director: Josep Vañó Chic[en] The aim of this project is the analysis, design and implementation of a website to settle the basis of an Internet platform addressed to the local trade. Hence, it looks for the reduction of effort and dedication to have a webpage that those businesses hold. The platform has been implemented using the web framework Django of Python for the backend and for the frontend HTML and Bootstrap. The platform will allow the commercial association to have a webpage to be made known by the customers and collect all their data. It will also permit each business to have an area to expose all its information, updates and products geared towards the customers. There are multiple management areas within the application where data can be modified and updated. Moreover, there is a section for the trade association and another for each trade. It has to be emphasized that the access, the visualization and modification of data is restricted to the entrance permissions of each user. The design of the interface is responsive, that is, it adapts to the device from which the webpage is consulted. Thus, the app allows being used from any device without losing functionalities. The project's purpose is to deeply know a web-framework which is greatly used in the nowadays society. Meanwhile, learnings about how to create a webpage from scratch will be done in this paper

    Enhanced virtual microscopy for collaborative education

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    <p>Abstract</p> <p>Background</p> <p>Curricular reform efforts and a desire to use novel educational strategies that foster student collaboration are challenging the traditional microscope-based teaching of histology. Computer-based histology teaching tools and Virtual Microscopes (VM), computer-based digital slide viewers, have been shown to be effective and efficient educational strategies. We developed an open-source VM system based on the Google Maps engine to transform our histology education and introduce new teaching methods. This VM allows students and faculty to collaboratively create content, annotate slides with markers, and it is enhanced with social networking features to give the community of learners more control over the system.</p> <p>Results</p> <p>We currently have 1,037 slides in our VM system comprised of 39,386,941 individual JPEG files that take up 349 gigabytes of server storage space. Of those slides 682 are for general teaching and available to our students and the public; the remaining 355 slides are used for practical exams and have restricted access. The system has seen extensive use with 289,352 unique slide views to date. Students viewed an average of 56.3 slides per month during the histology course and accessed the system at all hours of the day. Of the 621 annotations added to 126 slides 26.2% were added by faculty and 73.8% by students. The use of the VM system reduced the amount of time faculty spent administering the course by 210 hours, but did not reduce the number of laboratory sessions or the number of required faculty. Laboratory sessions were reduced from three hours to two hours each due to the efficiencies in the workflow of the VM system.</p> <p>Conclusions</p> <p>Our virtual microscope system has been an effective solution to the challenges facing traditional histopathology laboratories and the novel needs of our revised curriculum. The web-based system allowed us to empower learners to have greater control over their content, as well as the ability to work together in collaborative groups. The VM system saved faculty time and there was no significant difference in student performance on an identical practical exam before and after its adoption. We have made the source code of our VM freely available and encourage use of the publically available slides on our website.</p

    Instal·lacions de baix risc de proliferació i dispersió de legionel·la: anàlisi de circuits i eines de control

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    Legionel·la; Control oficial; Seguretat ambientalLegionela; Control oficial; Seguridad ambientalLegionella; Official control; Environmental securityAquesta Comunitat de Pràctica (CoP) es va crear amb l’objectiu de disposar d’uns documents, consensuats per tècnics de les diferents administracions implicades en el control i la prevenció de la legionel·losi (ASPCAT, DIBA, municipis, i, fins i tot, el Govern andorrà), perquè siguin una eina pràctica de treball. En un mateix model s’inclou la normativa, la informació ja disponible i les recomanacions tècniques per a aquells paràmetres que no conté ni la normativa ni la informació complementària ja disponible. D’una banda, aquests documents han de permetre la inspecció, tant als tècnics de l’ASPCAT com als tècnics municipals i/o a altres institucions encarregades de fer aquestes tasques. D’una altra banda, han de servir per donar suport a tots els agents implicats en la gestió i el control d’aquestes instal·lacions de baix risc. Presentem la documentació generada fins ara. Som conscients que no està del tot acabada i esperem que aquesta CoP tingui la continuïtat necessària per tal de concloure aquests documents i, si és possible, d’ampliar-los a altres instal·lacions de baix risc. Esperem que això ajudi a millorar l’estat higienicosanitari de les instal·lacions considerades de baix risc i a disminuir els brots i els casos de legionel·losi que, en els darrers anys, s’ha detectat que podrien ser les principals causants d’aquesta malaltia al nostre territori.Esta Comunidad de Práctica (CoP) se creó con el objetivo de disponer de unos documentos, consensuados por técnicos de las diferentes administraciones implicadas en el control y la prevención de la legionelosis (ASPCAT, DIBA, municipios, y, hasta y todo, el Gobierno andorrano), para que sean una herramienta práctica de trabajo. En un mismo modelo se incluye la normativa, información ya disponible y recomendaciones técnicas para aquellos parámetros que no contiene ni la normativa ni la información complementaria ya disponible. Por un lado, estos documentos deben permitir la inspección, tanto a los técnicos de la ASPCAT como a los técnicos municipales y/oa otras instituciones encargadas de realizar estas tareas. Por otro lado, deben servir para apoyar a todos los agentes implicados en la gestión y control de estas instalaciones de bajo riesgo. Presentamos la documentación generada hasta ahora. Somos conscientes de que no está del todo terminada y esperamos que esta CoP tenga la continuidad necesaria para concluir estos documentos y, si es posible, ampliarlos a otras instalaciones de bajo riesgo. Esperamos que esto ayude a mejorar el estado higiénico-sanitario de las instalaciones consideradas de bajo riesgo ya disminuir los brotes y los casos de legionelosis que, en los últimos años, se ha detectado que podrían ser las principales causantes de ésta enfermedad en nuestro territorio.This Community of Practice (CoP) was created with the aim of having some documents agreed upon by technicians from the different administrations involved in the control and prevention of legionellosis (ASPCAT, DIBA, municipalities, and, even and all, the Government Andorran), so that they are a practical work tool. The same model includes the regulations, information already available and technical recommendations for those parameters that neither the regulations nor the complementary information already available contain. On the one hand, these documents must allow inspection, both by ASPCAT technicians and by municipal technicians and/or other institutions in charge of carrying out these tasks. On the other hand, they must serve to support all the agents involved in the management and control of these low-risk facilities. We present the documentation generated so far. We are aware that it is not completely finished and we hope that this CoP will have the necessary continuity to finalize these documents and, if possible, extend them to other low-risk facilities. We hope this will help improve the hygienic-sanitary status of facilities considered low risk and reduce outbreaks and cases of legionellosis which, in recent years, have been found to be the main causes of this disease in our territory

    Discovery and Creation: Alternative Theories of Entrepreneurial Action

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    As oportunidades empreendedoras existem, independentemente, das percepções dos empreendedores, esperando apenas para serem descobertas? Ou, estas oportunidades são criadas pelas ações dos empreendedores? Duas teorias, internamente, consistentes com as oportunidades empreendedoras são: teoria da criação e teoria da descoberta- as quais serão descritas. Enquanto, será sempre possível, descrever a formação de uma oportunidade particular, como exemplo, de um processo da descoberta ou da criação de oportunidade, estas duas teorias têm implicações importantes para a eficácia de uma variedade ampla de ações empreendedoras em contextos diferentes. As implicações destas teorias para sete destas ações serão descritas, acompanhadas de uma discussão sobre algumas das implicações teóricas mais amplas destas duas teorias para os campos do empreendimento e do gerenciamento estratégico

    Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

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    In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Accordingly, it is important to update these guidelines for monitoring autophagy in different organisms. Various reviews have described the range of assays that have been used for this purpose. Nevertheless, there continues to be confusion regarding acceptable methods to measure autophagy, especially in multicellular eukaryotes. For example, a key point that needs to be emphasized is that there is a difference between measurements that monitor the numbers or volume of autophagic elements (e.g., autophagosomes or autolysosomes) at any stage of the autophagic process versus those that measure fl ux through the autophagy pathway (i.e., the complete process including the amount and rate of cargo sequestered and degraded). In particular, a block in macroautophagy that results in autophagosome accumulation must be differentiated from stimuli that increase autophagic activity, defi ned as increased autophagy induction coupled with increased delivery to, and degradation within, lysosomes (inmost higher eukaryotes and some protists such as Dictyostelium ) or the vacuole (in plants and fungi). In other words, it is especially important that investigators new to the fi eld understand that the appearance of more autophagosomes does not necessarily equate with more autophagy. In fact, in many cases, autophagosomes accumulate because of a block in trafficking to lysosomes without a concomitant change in autophagosome biogenesis, whereas an increase in autolysosomes may reflect a reduction in degradative activity. It is worth emphasizing here that lysosomal digestion is a stage of autophagy and evaluating its competence is a crucial part of the evaluation of autophagic flux, or complete autophagy. Here, we present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes. These guidelines are not meant to be a formulaic set of rules, because the appropriate assays depend in part on the question being asked and the system being used. In addition, we emphasize that no individual assay is guaranteed to be the most appropriate one in every situation, and we strongly recommend the use of multiple assays to monitor autophagy. Along these lines, because of the potential for pleiotropic effects due to blocking autophagy through genetic manipulation it is imperative to delete or knock down more than one autophagy-related gene. In addition, some individual Atg proteins, or groups of proteins, are involved in other cellular pathways so not all Atg proteins can be used as a specific marker for an autophagic process. In these guidelines, we consider these various methods of assessing autophagy and what information can, or cannot, be obtained from them. Finally, by discussing the merits and limits of particular autophagy assays, we hope to encourage technical innovation in the field
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