612 research outputs found
Parity-violating asymmetry in with a pionless effective theory
Nuclear parity violation is studied with polarized neutrons in the
photodisintegration of the deuteron at low energies. A pionless effective field
theory with di-baryon fields is used for the investigation. Hadronic weak
interactions are treated by parity-violating di-baryon-nucleon-nucleon
vertices, which have undetermined coupling contants. A parity-violating
asymmetry in the process is calculated for the incident photon energy up to 30
MeV. If experimental data for the parity-violating asymmetry become available
in the future, we will be able to determine the unknown coupling contants in
the parity-violating vertices.Comment: 4 pages. A contribution to APFB2011, August 22-26, 2011, Seoul, Kore
Structure of Full-Length SMC and Rearrangements Required for Chromosome Organization.
Multi-subunit SMC complexes control chromosome superstructure and promote chromosome disjunction, conceivably by actively translocating along DNA double helices. SMC subunits comprise an ABC ATPase "head" and a "hinge" dimerization domain connected by a 49Â nm coiled-coil "arm." The heads undergo ATP-dependent engagement and disengagement to drive SMC action on the chromosome. Here, we elucidate the architecture of prokaryotic Smc dimers by high-throughput cysteine cross-linking and crystallography. Co-alignment of the Smc arms tightly closes the interarm space and misaligns the Smc head domains at the end of the rod by close apposition of their ABC signature motifs. Sandwiching of ATP molecules between Smc heads requires them to substantially tilt and translate relative to each other, thereby opening up the Smc arms. We show that this mechanochemical gating reaction regulates chromosome targeting and propose a mechanism for DNA translocation based on the merging of DNA loops upon closure of Smc arms
Hybrid materials based on polyethylene and MCM-41 microparticles functionalized with silanes: catalytic aspects of in situ polymerization, crystalline features and mechanical properties
New nanocomposites based on polyethylene have been prepared by in situ polymerization of ethylene in
presence of mesoporous MCM-41. The polymerization reactions were performed using a zirconocene
catalyst either under homogenous conditions or supported onto mesoporous MCM-41 particles, which
are synthesized and decorated post-synthesis with two silanes before polymerization in order to promote
an enhanced interfacial adhesion. The existence of polyethylene chains able to crystallize within
the mesoporous channels in the resulting nanocomposites is figured out from the small endothermic
process, located at around 80 C, on heating calorimetric experiments, in addition to the main melting
endotherm. These results indicate that polyethylene macrochains can grow up during polymerization
either outside or inside the MCM-41 channels, these keeping their regular hexagonal arrangements.
Mechanical response is observed to be dependent on the content in mesoporous MCM-41 and on the
crystalline features of polyethylene. Accordingly, stiffness increases and deformability decreases in the
nanocomposites as much as MCM-41 content is enlarged and polyethylene amount within channels is
raised. Ultimate mechanical performance improves with MCM-41 incorporation without varying the
final processing temperature
Cerebellar Nuclear Neurons Use Time and Rate Coding to Transmit Purkinje Neuron Pauses
Copyright: © 2015 Sudhakar et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are creditedNeurons of the cerebellar nuclei convey the final output of the cerebellum to their targets in various parts of the brain. Within the cerebellum their direct upstream connections originate from inhibitory Purkinje neurons. Purkinje neurons have a complex firing pattern of regular spikes interrupted by intermittent pauses of variable length. How can the cerebellar nucleus process this complex input pattern? In this modeling study, we investigate different forms of Purkinje neuron simple spike pause synchrony and its influence on candidate coding strategies in the cerebellar nuclei. That is, we investigate how different alignments of synchronous pauses in synthetic Purkinje neuron spike trains affect either time-locking or rate-changes in the downstream nuclei. We find that Purkinje neuron synchrony is mainly represented by changes in the firing rate of cerebellar nuclei neurons. Pause beginning synchronization produced a unique effect on nuclei neuron firing, while the effect of pause ending and pause overlapping synchronization could not be distinguished from each other. Pause beginning synchronization produced better time-locking of nuclear neurons for short length pauses. We also characterize the effect of pause length and spike jitter on the nuclear neuron firing. Additionally, we find that the rate of rebound responses in nuclear neurons after a synchronous pause is controlled by the firing rate of Purkinje neurons preceding it.Peer reviewedFinal Published versio
Investigating the effect of GaCl3 incorporation into the usual CdCl2 treatment on CdTe-based solar cell device structures
The incorporation of GaCl3 into the usual CdCl2 post-deposition treatment solution of CdTe-based solar cells has been investigated. Both CdS and CdTe layers used in this work were prepared by electroplating technique and they are n-type in electrical conduction as observed from photoelectrochemical cell measurement technique. Before applying the chemical treatments to the device structures, the effect of GaCl3 incorporation into the usual CdCl2 treatment was first studied on the structural and optical properties of CdTe thin films. The results of the optical properties show that the bandgap of CdTe thin films treated with a mixture of GaCl3 + CdCl2 is closer to that of bulk CdTe layers than the ones treated only with CdCl2 solution. The structural properties also showed that CdTe thin films treated with GaCl3 + CdCl2 is more crystalline than CdTe thin films treated only with CdCl2 solution. The addition of GaCl3 into the CdCl2 solution have been seen to drastically enhance the solar-to-electric conversion efficiency of CdS/CdTe based solar cells. One of the effects of Ga incorporation into the usual CdCl2 treatment was seen in the series resistance reduction which ultimately leads to enhancement in the observed short-circuit current density, fill factor and overall solar cell efficiency. For the glass/FTO/n-CdS/n-CdTe device structures, the cell efficiencies were observed in the range 1.9â2.1% after being treated with CdCl2 solution only. When treated with CdCl2 + GaCl3, the efficiency increased to 6.1â6.4%. Subsequent study on multi-junction graded bandgap solar cells using the GaCl3 + CdCl2 chemical solution for the surface treatment of glass/FTO/n-ZnS/n-CdS/n-CdTe device structures results in solar cell efficiency >10%
Proximity effect at superconducting Sn-Bi2Se3 interface
We have investigated the conductance spectra of Sn-Bi2Se3 interface junctions
down to 250 mK and in different magnetic fields. A number of conductance
anomalies were observed below the superconducting transition temperature of Sn,
including a small gap different from that of Sn, and a zero-bias conductance
peak growing up at lower temperatures. We discussed the possible origins of the
smaller gap and the zero-bias conductance peak. These phenomena support that a
proximity-effect-induced chiral superconducting phase is formed at the
interface between the superconducting Sn and the strong spin-orbit coupling
material Bi2Se3.Comment: 7 pages, 8 figure
Centrality Dependence of the High p_T Charged Hadron Suppression in Au+Au collisions at sqrt(s_NN) = 130 GeV
PHENIX has measured the centrality dependence of charged hadron p_T spectra
from central Au+Au collisions at sqrt(s_NN)=130 GeV. The truncated mean p_T
decreases with centrality for p_T > 2 GeV/c, indicating an apparent reduction
of the contribution from hard scattering to high p_T hadron production. For
central collisions the yield at high p_T is shown to be suppressed compared to
binary nucleon-nucleon collision scaling of p+p data. This suppression is
monotonically increasing with centrality, but most of the change occurs below
30% centrality, i.e. for collisions with less than about 140 participating
nucleons. The observed p_T and centrality dependence is consistent with the
particle production predicted by models including hard scattering and
subsequent energy loss of the scattered partons in the dense matter created in
the collisions.Comment: 7 pages text, LaTeX, 6 figures, 2 tables, 307 authors, resubmitted to
Phys. Lett. B. Revised to address referee concerns. Plain text data tables
for the points plotted in figures for this and previous PHENIX publications
are publicly available at
http://www.phenix.bnl.gov/phenix/WWW/run/phenix/papers.htm
Formation of dense partonic matter in relativistic nucleus-nucleus collisions at RHIC: Experimental evaluation by the PHENIX collaboration
Extensive experimental data from high-energy nucleus-nucleus collisions were
recorded using the PHENIX detector at the Relativistic Heavy Ion Collider
(RHIC). The comprehensive set of measurements from the first three years of
RHIC operation includes charged particle multiplicities, transverse energy,
yield ratios and spectra of identified hadrons in a wide range of transverse
momenta (p_T), elliptic flow, two-particle correlations, non-statistical
fluctuations, and suppression of particle production at high p_T. The results
are examined with an emphasis on implications for the formation of a new state
of dense matter. We find that the state of matter created at RHIC cannot be
described in terms of ordinary color neutral hadrons.Comment: 510 authors, 127 pages text, 56 figures, 1 tables, LaTeX. Submitted
to Nuclear Physics A as a regular article; v3 has minor changes in response
to referee comments. Plain text data tables for the points plotted in figures
for this and previous PHENIX publications are (or will be) publicly available
at http://www.phenix.bnl.gov/papers.htm
An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics
For a decade, The Cancer Genome Atlas (TCGA) program collected clinicopathologic annotation data along with multi-platform molecular profiles of more than 11,000 human tumors across 33 different cancer types. TCGA clinical data contain key features representing the democratized nature of the data collection process. To ensure proper use of this large clinical dataset associated with genomic features, we developed a standardized dataset named the TCGA Pan-Cancer Clinical Data Resource (TCGA-CDR), which includes four major clinical outcome endpoints. In addition to detailing major challenges and statistical limitations encountered during the effort of integrating the acquired clinical data, we present a summary that includes endpoint usage recommendations for each cancer type. These TCGA-CDR findings appear to be consistent with cancer genomics studies independent of the TCGA effort and provide opportunities for investigating cancer biology using clinical correlates at an unprecedented scale. Analysis of clinicopathologic annotations for over 11,000 cancer patients in the TCGA program leads to the generation of TCGA Clinical Data Resource, which provides recommendations of clinical outcome endpoint usage for 33 cancer types
Measurement of the polarisation of W bosons produced with large transverse momentum in pp collisions at sqrt(s) = 7 TeV with the ATLAS experiment
This paper describes an analysis of the angular distribution of W->enu and
W->munu decays, using data from pp collisions at sqrt(s) = 7 TeV recorded with
the ATLAS detector at the LHC in 2010, corresponding to an integrated
luminosity of about 35 pb^-1. Using the decay lepton transverse momentum and
the missing transverse energy, the W decay angular distribution projected onto
the transverse plane is obtained and analysed in terms of helicity fractions
f0, fL and fR over two ranges of W transverse momentum (ptw): 35 < ptw < 50 GeV
and ptw > 50 GeV. Good agreement is found with theoretical predictions. For ptw
> 50 GeV, the values of f0 and fL-fR, averaged over charge and lepton flavour,
are measured to be : f0 = 0.127 +/- 0.030 +/- 0.108 and fL-fR = 0.252 +/- 0.017
+/- 0.030, where the first uncertainties are statistical, and the second
include all systematic effects.Comment: 19 pages plus author list (34 pages total), 9 figures, 11 tables,
revised author list, matches European Journal of Physics C versio
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