868 research outputs found
Comparison of local pole assignment methods
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/76770/1/AIAA-20171-818.pd
Direct sampling of exponential phase moments of smoothed Wigner functions
We investigate exponential phase moments of the s-parametrized
quasidistributions (smoothed Wigner functions). We show that the knowledge of
these moments as functions of s provides, together with photon-number
statistics, a complete description of the quantum state. We demonstrate that
the exponential phase moments can be directly sampled from the data recorded in
balanced homodyne detection and we present simple expressions for the sampling
kernels. The phase moments are Fourier coefficients of phase distributions
obtained from the quasidistributions via integration over the radial variable
in polar coordinates. We performed Monte Carlo simulations of the homodyne
detection and we demonstrate the feasibility of direct sampling of the moments
and subsequent reconstruction of the phase distribution.Comment: RevTeX, 8 pages, 6 figures, accepted Phys. Rev.
Reliability and realizability risk evaluation of concept designs
This thesis addresses the improvement in quality of decision making in design through the use of decomposed design evaluation. The research reported in this thesis is supported by the Design Research Methodology. To perform decomposed decision making, it is necessary to identify criteria that are deemed important for this activity. Questionnaire surveys, literature review and interviews with industry helped to identify these criteria. Reliability and realizability are two criteria that are selected for research in this thesis. The questionnaire surveys are discussed in chapter 2. A review of literature on decision making, reliability and realizability is reported in chapters 3 and 4. Methodologies for evaluating reliability and physical realizability are discussed in chapter 5. Relative reliability risk assessment methodology is applied to various examples consisting of university and industry projects in chapter 6. The application helps to reveal the strengths of the methodology and is termed ‘Verification of the methodology’. Validation issues of both the methodologies are dealt with in chapter 7 using the controlled experimental design. It is found that both the methodologies help to improve the quality of decision making during design evaluation. Relative reliability risk evaluation methodology helps to improve the quality of decision making to a substantial extent but physical realizability evaluation methodology shows only a little improvement in quality of decision making. Finally, it is suggested that the decomposed design evaluation methodology helps to improve the quality of decision making and is therefore proposed to be used by both novice and experienced designers.EThOS - Electronic Theses Online ServiceGBUnited Kingdo
Mode structure and ray dynamics of a parabolic dome microcavity
We consider the wave and ray dynamics of the electromagnetic field in a
parabolic dome microcavity. The structure of the fundamental s-wave involves a
main lobe in which the electromagnetic field is confined around the focal point
in an effective volume of the order of a cubic wavelength, while the modes with
finite angular momentum have a structure that avoids the focal area and have
correspondingly larger effective volume. The ray dynamics indicates that the
fundamental s-wave is robust with respect to small geometrical deformations of
the cavity, while the higher order modes are associated with ray chaos and
short-lived. We discuss the incidence of these results on the modification of
the spontaneous emission dynamics of an emitter placed in such a parabolic dome
microcavity.Comment: 50 pages, 17 figure
Designing Cathodes and Cathode Active Materials for Solid State Batteries
Solid state batteries SSBs currently attract great attention as a potentially safe electrochemical high energy storage concept. However, several issues still prevent SSBs from outperforming today s lithium ion batteries based on liquid electrolytes. One major challenge is related to the design of cathode active materials CAMs that are compatible with the superionic solid electrolytes SEs of interest. This perspective, gives a brief overview of the required properties and possible challenges for inorganic CAMs employed in SSBs, and describes state of the art solutions. In particular, the issue of tailoring CAMs is structured into challenges arising on the cathode , particle , and interface level, related to microstructural, chemo mechanical, and electro chemical interplay of CAMs with SEs, and finally guidelines for future CAM development for SSBs are propose
Leading order determination of the gluon polarisation from DIS events with high-p_T hadron pairs
We present a determination of the gluon polarisation Delta g/g in the
nucleon, based on the longitudinal double-spin asymmetry of DIS events with a
pair of large transverse-momentum hadrons in the final state. The data were
obtained by the COMPASS experiment at CERN using a 160 GeV/c polarised muon
beam scattering off a polarised ^6LiD target. The gluon polarisation is
evaluated by a Neural Network approach for three intervals of the gluon
momentum fraction x_g covering the range 0.04 < x_g < 0.27. The values obtained
at leading order in QCD do not show any significant dependence on x_g. Their
average is Delta g/g = 0.125 +/- 0.060 (stat.) +/- 0.063 (syst.) at x_g=0.09
and a scale of mu^2 = 3 (GeV/c)^2.Comment: 13 pages, 6 figures and 3 table
Binding adaptation of GS 441524 diversifies macro domains and downregulate SARS CoV 2 de MARylation capacity
Viral infection in cells triggers a cascade of molecular defense mechanisms to maintain host cell homoeostasis. One of these mechanisms is ADP ribosylation, a fundamental post translational modification PTM characterized by the addition of ADP ribose ADPr on substrates. Poly ADP ribose polymerases PARPs are implicated in this process and they perform ADP ribosylation on host and pathogen proteins. Some viral families contain structural motifs that can reverse this PTM. These motifs known as macro domains MDs are evolutionarily conserved protein domains found in all kingdoms of life. They are divided in different classes with the viral belonging to Macro D type class because of their properties to recognize and revert the ADP ribosylation. Viral MDs are potential pharmaceutical targets, capable to counteract host immune response. Sequence and structural homology between viral and human MDs are an impediment for the development of new active compounds against their function. Remdesivir, is a drug administrated in viral infections inhibiting viral replication through RNA dependent RNA polymerase RdRp . Herein, GS 441524, the active metabolite of the remdesivir, is tested as a hydrolase inhibitor for several viral MDs and for its binding to human homologs found in PARPs. This study presents biochemical and biophysical studies, which indicate that GS 441524 selectively modifies SARS CoV 2 MD de MARylation activity, while it does not interact with hPARP14 MD2 and hPARP15 MD2. The structural investigation of MD GS 441524 complexes, using solution NMR and X ray crystallography, discloses the impact of certain amino acids in ADPr binding cavity suggesting that F360 and its adjacent residues tune the selective binding of the inhibitor to SARS CoV 2 M
Search for direct production of charginos and neutralinos in events with three leptons and missing transverse momentum in √s = 7 TeV pp collisions with the ATLAS detector
A search for the direct production of charginos and neutralinos in final states with three electrons or muons and missing transverse momentum is presented. The analysis is based on 4.7 fb−1 of proton–proton collision data delivered by the Large Hadron Collider and recorded with the ATLAS detector. Observations are consistent with Standard Model expectations in three signal regions that are either depleted or enriched in Z-boson decays. Upper limits at 95% confidence level are set in R-parity conserving phenomenological minimal supersymmetric models and in simplified models, significantly extending previous results
Anisotropic flow of charged hadrons, pions and (anti-)protons measured at high transverse momentum in Pb-Pb collisions at TeV
The elliptic, , triangular, , and quadrangular, , azimuthal
anisotropic flow coefficients are measured for unidentified charged particles,
pions and (anti-)protons in Pb-Pb collisions at TeV
with the ALICE detector at the Large Hadron Collider. Results obtained with the
event plane and four-particle cumulant methods are reported for the
pseudo-rapidity range at different collision centralities and as a
function of transverse momentum, , out to GeV/.
The observed non-zero elliptic and triangular flow depends only weakly on
transverse momentum for GeV/. The small dependence
of the difference between elliptic flow results obtained from the event plane
and four-particle cumulant methods suggests a common origin of flow
fluctuations up to GeV/. The magnitude of the (anti-)proton
elliptic and triangular flow is larger than that of pions out to at least
GeV/ indicating that the particle type dependence persists out
to high .Comment: 16 pages, 5 captioned figures, authors from page 11, published
version, figures at http://aliceinfo.cern.ch/ArtSubmission/node/186
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