Le médicament vétérinaire et la lutte contre l'antibiorésistance (contribution à l'étude scientifique du débat et de ses enjeux à partir d'une double analyse, bibliographique et expérimentale (étude qualitative de la littérature professionnelle des vétérinaires et des pharmaciens))

LYON1-BU Santé (693882101) / SudocTOULOUSE-EN Vétérinaire (315552301) / SudocSudocFranceF

How about Habitats and Darwin Core?

As part of the Biodiversity Information System on Nature and Landscapes (SINP), the French National Museum of Natural History was appointed to develop biodiversity data exchange standards, with the goal of sharing French marine and terrestrial data nationally, meeting domestic and European requirements, e.g., the Infrastructure for spatial information in Europe Directive (INSPIRE Directive, European Commission 2007). Data standards are now recognised as useful to improve and share biodiversity knowledge (e.g., species distribution) and play a key role in data valorisation (e.g., vulnerability assessment, conservation policy). For example, in order to fulfill report obligations within the Fauna and Flora Habitats Directive (European Commission 1992), and the Marine Strategy Framework Directive (European Commission 2008), information about taxa and habitat occurrences are required periodically, involving data exchange and compilation at a national scale. National and international data exchange standards are focused on species, and only a few solutions exist when there is a need to deal with habitat data. Darwin Core has been built to fit with species data exchange needs and only contains one habitat attribute that allows for a bit of leeway to have such an information transfer, but is deemed to be one of the least standardized fields. However, Darwin Core does not allow for a transit of only habitat data, as the scientific name of the taxon is mandatory. The SINP standard for habitats was developed by a dedicated working group, representative of biodiversity European Commission 2008 stakeholders in France. This standard focuses on core attributes that characterize habitat observation and monitoring. Interoperability remains to be achieved with the Darwin Core standard, or something similar on a world scale (e.g., Humboldt Core), as habitat data are regularly gathered irrespective of whether taxon occurrences are associated with it. The results of the French initiative proved useful to compile and share data nationally, bringing together data providers that otherwise would have been excluded. However, at a global scale, it faces some challenges that still need to be fully addressed, interoperability being the main one. Regardless of the problems that remain to be solved, some lessons can be learnt from this effort. With the ultimate goal of making biodiversity data readily available, these lessons should be kept in mind for future initiatives. The presentation deals with how this work was undertaken and how the required elements could be integrated into a French national standard to allow for comprehensive habitat data reporting. It will show hypothesis as to what could be added to the Darwin Core to allow for a better understanding of habitats with at least one taxon attached (or not) to them

A new species of Agonimia (Ascomycota, Eurotiomycetes, Verrucariaceae) from Morane atoll (Tuāmotu-Gambier Islands, French Polynesia)

International audienceAgonimia gargominyi (Verrucariaceae, Verrucariales) is described and illustrated from bark samples collected from Morane atoll (Tuāmotu-Gambier Islands, French Polynesia). It is characterized by the large superficial perithecia having a pale brown-colored ostiolar region, the 8-spored asci, and the relatively large lobed squamules. Micromorphology of the ascomata and the thalline squamules matches the genus Agonimia. Additionally, to accommodate the inclusion of this newly identified species, the existing comprehensive key encompassing all known Agonimia species worldwide has been modified and updated accordingly. Detailed illustrations supplement the description of Agonimia gargominyi

Chemical diversity of five coastal Roccella species from mainland France, the Scattered Islands, and São Tomé and Príncipe

International audienceRoccella species constitute interesting models to address questions regarding lichen metabolite diversity across taxonomic, ecological and geographic gradients. Indeed, owing to their wide distribution, their taxonomic diversity and the narrow ecological niche they occupy, Roccella species are good candidates to study the drivers of lichen chemistry. This study focuses on the chemical profiling of five species: R. applanata, R. belangeriana, R. fuciformis, R. montagnei and R. phycopsis. These five species were sampled in a rather narrow longitudinal range (W1°51' to E47°17') covering the Eastern Atlantic and Western Indian Ocean areas along an extended latitudinal range (N48°49' to S22°23'). High Pressure Liquid Chromatography (HPLC) analysis followed by mass spectrometry of 31 Roccella thalli revealed a number of interesting patterns through a multivariate (PCA) analysis, including the first detailed chemical profiles for two species from the Scattered Islands: R. applanata and R. belangeriana. Metabolite segregation amongst all studied Roccella species, including R. montagnei and R. belangeriana, gave some insight into the taxonomy of the latter two species, which we interpret as separate species. An additional analysis focusing on R. montagnei samples revealed chemical differences along both a latitudinal and ecological gradient (from Europa to São Tomé and Príncipe). Three mass spectra databases were built to dereplicate the ions, which gave an overview of the factors that could drive quantitative and qualitative metabolite composition in lichens. Additionally, several new Roccella species records are reported for the Scattered Islands as well as São Tomé and Príncipe

Effects of medial temporal lobe degeneration on brain perfusion in amnestic MCI of AD type: deafferentation and functional compensation?

International audiencePURPOSE: Cortical atrophy is correlated with the progression of neuropathological lesions within the medial temporal lobes (MTL) in Alzheimer's disease (AD). Our aim was to determine which local and remote functional changes result from MTL volume loss at the predementia stage. METHODS: We studied the relationship between entorhinal and hippocampal MR volumes and whole-brain SPECT perfusion via a voxel-based correlative analysis in 19 patients with amnestic mild cognitive impairment with a memory profile suggestive of early AD. RESULTS: Right MTL volumes were positively correlated with remote posterior perfusion of the posterior cingulate cortex, and negatively correlated with remote anterior perfusion of the right medial and dorsolateral prefrontal cortex. There was no local correlation between volumes and perfusion within the MTL. CONCLUSION: These findings provide further insight into functional changes that result from MTL volume loss during the predementia stage of AD. The positive correlation between MTL volumes and posterior cingulate perfusion may reflect the deafferentation of a temporocingulate network due to mediotemporal degeneration. The paradoxical negative correlation between MTL volumes and prefrontal perfusion may result from recruitment of an alternative anterior temporofrontal network. It remains to be investigated how the "net sum" of this perfusion modulation affects memory and other cognitive domains through a possible compensatory perspective