Stroke treatment academic industry roundtable recommendations for individual data pooling analyses in stroke

Pooled analysis of individual patient data from stroke trials can deliver more precise estimates of treatment effect, enhance power to examine prespecified subgroups, and facilitate exploration of treatment-modifying influences. Analysis plans should be declared, and preferably published, before trial results are known. For pooling trials that used diverse analytic approaches, an ordinal analysis is favored, with justification for considering deaths and severe disability jointly. Because trial pooling is an incremental process, analyses should follow a sequential approach, with statistical adjustment for iterations. Updated analyses should be published when revised conclusions have a clinical implication. However, caution is recommended in declaring pooled findings that may prejudice ongoing trials, unless clinical implications are compelling. All contributing trial teams should contribute to leadership, data verification, and authorship of pooled analyses. Development work is needed to enable reliable inferences to be drawn about individual drug or device effects that contribute to a pooled analysis, versus a class effect, if the treatment strategy combines ≥2 such drugs or devices. Despite the practical challenges, pooled analyses are powerful and essential tools in interpreting clinical trial findings and advancing clinical care

Una cartografía de las desigualdades y los conflictos desde los sistema mundo

Los mapas siempre nos ayudan a tener una visión, si no exacta, por lo menos general, de los fenómenos; el libro reseñado es eso, un mapa particular de las crisis globales vistas desde la investigación para la paz y la teoría de los sistema mundo, como acercamientos teórico-metodológicos a las desigualdades, los con ictos y las violencias que se producen en estas nuevas relaciones NorteSur. Sin embargo, es una cartografía que analiza las crisis de los países centrales, que los hacen transitar a las fronteras de lo periférico y sus consecuencias para los países considerados periféricos

La violencia mediática: un estudio de caso

El presente trabajo tiene como objetivo plantear cómo se representa la violencia en los medios de comunicación, para ese efecto se realiza un análisis de notas periodísticas referentes a la realidad del Estado de México, en los meses de junio a agosto de 2005 -periodo de actividad electoral-, a partir de dos periódicos, uno netamente lo cal (El Sol de Toluca) y otro de corte nacional, en su sección "Estado" (Reforma). Para lograr dicho objetivo se ocupó como metodología el análisis del discurso, específicamente en su variante de las macroestructuras semánticas (resumen, titular y encabezamiento de la nota periodística), sobre las cuales se efectúa un análisis del tipo y forma de la argumentación; es decir, las macroestructuras entendidas como ese conjunto jerárquico de temas que conforman la estructura temática del texto, permitió centrar el análisis en el problema de la violencia, identificar los elementos dominantes, examinar la gama de diferencias y diversidad de estilos, así como la diversidad de discursos que la prensa construye en torno a la violencia. Describir los discursos, en gen eral, y los de la violencia, en particular, nos posibilita comprender de qué manera la prensa, en tanto institución mediática, tiene un papel importante en la construcción de la realidad

A week with Professor Giacomo Rizzolatti (30th of November - 6th of December 2015)

Professor Giacomo Rizzolatti, Professor Emeritus in physiology at the University of Parma, is the discoverer of `mirror neurons' and director of the `Social and Mo- tor Cognition' centre at the Italian Institute of Technology. From January 2016 he has been appointed by the Rector Professor Jaunito Camilleri as Senior Researcher Advisor by the University of Malta within the Department of Physiology and Biochemistry. Award winner and world-renowned neuroscientist, Professor Giacomo Rizzolatti received the `Brain Prize' in 2014, a prestigious prize for brain research bestowed by the Grete Lundbeck European Brain Research Prize Foundation in Copenhagen. Professor Giacomo Rizzolatti was invited by Professor Giuseppe Di Giovanni on behalf of the Malta Neuroscience Network Program of the University of Malta as key-note speaker at the IX Malta Medical School Conference (MMSC), the most important event for the local medical community, which this year was held in St. Julian at the Hilton Hotel from the 3rd to the 5th of December. The conference, for the second time, had different sessions in Neuroscience and for the first time a commune session in neurology-neuroscience.peer-reviewe

Review on sponge city construction for flood management

Due to the global climate change and the rapid progress of urbanization, the frequent occurrence of flooding disasters and severe pollution seriously threaten the sustainable development of modern cities. To solve these problems, China first started the construction of the ‘Sponge City’. Sponge city can improve city’s ability to adapt to the environment change and to cope with floods; it can also make them more sustainable. It was not only meant for urban flood control, but also rainwater harvest, ecological restoration of urban land and water quality improvement. The rainfall received in 2020 in Hyderabad of India, has been the highest for the month October in a century. The risk is going to increase year after year in the whole nation. So India too needs a mission that mitigates flood risk and provides a pathway to water security. And the most promising solution across the world at this time can be the idea to adopt Sponge city construction. Improper research in this field will lead to huge maintenance difficulties and other related problems. This paper mainly focuses on presenting the concepts of sponge city construction along with its pathway. Not only does it focus on Sponge city’s benefits, but also its challenges are also stated, which leads to better understanding about its scope of continuing for future. Keywords: Flood control, sponge city, green infrastructure, urban floods

Denúncia, imaginário e Internet: como as redes sociais agendaram a mídia local a abordar a postura de estudantes fantasiados de Ku Klux Klan em escola de Salvador

O I Encontro Internacional do MALOCA Grupo de Estudos Multidisciplinares em Urbanismos e Arquiteturas do Sul teve por objetivo apresentar os resultados do seu primeiro triênio (2014-2016) e debater os rumos das pesquisas do grupo para o triênio 2017-2019. Divulgamos agora os Anais Eletrônicos do I Encontro, que aconteceu em outubro de 2017 na Universidade Federal da Integração Latino-Americana (UNILA). Confiram no link: https://revistas.unila.edu.br/anaismaloca/index :)O presente trabalho propõe uma reflexão em torno do papel social do jornalismo enquanto mediador das relações em sociedade, como instrumento social pautado na defesa dos princípios expressos na Declaração Universal dos Direitos Humanos – como apontado pelo Código de Ética dos Jornalistas Brasileiros –, e na qualidade de fomentador da construção do imaginário coletivo, a partir de estudo referente à cobertura dos meios de comunicação sobre o caso dos alunos de colégio particular em Salvador, Bahia, que se vestiram de membros da Ku Klux Klan em atividade escolar. Parte da população soteropolitana utilizou-se das redes sociais como espaço de denúncia, apresentação de ideias e discussão sobre o caso dos estudantes, agendando (McCOMBS; SHAW, 1972) a mídia local a cobrir o caso. Dessa forma, observa-se que a internet se configura como lugar de exercício de cidadania, pela participação direta política e social dos indivíduos, demonstrando a força que esse espaço tem socialmente como fomentador de discussões que serão reverberadas pela mídia (HABERMAS, 1984). Assim, compreenderemos como se deu a cobertura da mídia convencional sobre o caso a partir desse agendamento, através da análise de notícias publicadas em portais online da mídia localComplaint, imaginary and internet: how social networks set the local media to cover the attitudes of students dressed as Ku Klux Klan in a school in Salvador The present work proposes a reflection about the social role of journalism qua mediator of relations in society, as a social instrument based on the defense of the principles expressed on the Universal Declaration of Humans Rights – in accordance with the Brazilian journalists‘ ethical code –, and in quality of promoter of collective imaginary construction, from a study of the coverage of the media on the case of students of a private school in Salvador, Bahia, who dressed as Ku Klux Klan members in a school activity. Part of Salvador‘s population used social networks as a space of complaint, presentation of ideas and discussion of the case, setting (McCOMBS; SHAW, 1972) the local media to cover it. Thus, it is observed that the internet becomes a place of citizenship practice, through direct, social and political participation of individuals, evidencing the strength this space has socially as promoter of discussions that are reverberated by the media (HABERMAS, 1984). So, we understand how the media covered the case from this scheduling, through the analysis of news published on online sites of the local mediaGrupo de Estudos Multidisciplinar em Urbanismo e Arquitetura do Sul - MALOC