15 research outputs found
ICU-acquired infections on a patient-to-patient antibiotic rotation policy in ICU
- Publication venue
- BioMed Central
- Publication date
- 01/01/2001
- Field of study
Failure of bacterial filters to reduce respiratory infection incidence
- Author
- Publication venue
- BioMed Central
- Publication date
- 01/01/2001
- Field of study
Accidental withdrawal of tubes, sounds and catheters
- Author
- Publication venue
- BioMed Central
- Publication date
- 01/01/2001
- Field of study
Global urban environmental change drives adaptation in white clover.
- Author
- Aguirre WE
- Akinwole PO
- Alberti M
- Anderson JJ
- Anderson JT
- Ando Y
- Andrew NR
- Angeoletto F
- Anstett DN
- Anstett J
- Aoki-Gonçalves F
- Arietta AZA
- Arroyo MTK
- Austen EJ
- Baena-Díaz F
- Barker CA
- Baylis HA
- Beliz JM
- Benitez-Mora A
- Bickford D
- Biedebach G
- Blackburn GS
- Boehm MMA
- Bonser SP
- Bonte D
- Bragger JR
- Branquinho C
- Brans KI
- Bresciano JC
- Brom PD
- Bucharova A
- Burt B
- Cahill JF
- Campbell KD
- Carlen EJ
- Carmona D
- Castellanos MC
- Centenaro G
- Chalen I
- Chaves JA
- Chen X-Y
- Chilton AM
- Chomiak KM
- Chávez-Pesqueira M
- Cisneros-Heredia DF
- Cisse IK
- Classen AT
- Cohan B
- Comerford MS
- Corney H
- Crawford AJ
- Crawford KM
- Dahirel M
- David S
- De Haan R
- Deacon NJ
- Dean C
- Del-Val E
- Deligiannis EK
- Denney D
- Dettlaff MA
- DiLeo MF
- Ding Y-Y
- Dominoni DM
- Domínguez-López ME
- Draud SL
- Dyson K
- Ellers J
- Espinosa CI
- Essi L
- Falahati-Anbaran M
- Falcão JCF
- Fargo HT
- Fellowes MDE
- Fitzpatrick CR
- Fitzpatrick RM
- Flaherty LE
- Flood PJ
- Flores MF
- Fornoni J
- Foster AG
- Fradinger CC
- Frost CJ
- Fuentes TL
- Fulkerson JR
- Gagnon E
- Garbsch F
- Garroway CJ
- Gerstein AC
- Giasson MM
- Girdler EB
- Gkelis S
- Godsoe W
- Golemiec AM
- Golemiec M
- González-Lagos C
- Gorton AJ
- Gotanda KM
- Granath G
- Greiner S
- Griffiths JS
- Grilo F
- Gundel PE
- Hamilton B
- Hardin JM
- He T
- Heard SB
- Henriques AF
- Hernández-Poveda M
- Hetherington-Rauth MC
- Hill SJ
- Hochuli DF
- Hodgins KA
- Hood GR
- Hopkins GR
- Hovanes KA
- Howard AR
- Hubbard SC
- Ibarra-Cerdeña CN
- Innes SG
- Iñiguez-Armijos C
- Jara-Arancio P
- Jarrett BJM
- Jeannot M
- Jiménez-Lobato V
- Johnson M
- Johnson MTJ
- Johnson O
- Johnson PP
- Johnson R
- Josephson MP
- Jung MC
- Just MG
- Kahilainen A
- Kailing OS
- Kariñho-Betancourt E
- Karousou R
- Kirn LA
- Kirschbaum A
- Koch S
- Laine A-L
- LaMontagne JM
- Lampei C
- Lara C
- Larson EL
- Le JH
- Leandro DS
- Lee C
- Lei Y
- Lequerica Tamara ME
- Levesque DC
- León CA
- Liao W-J
- Ljubotina M
- Locke H
- Lockett MT
- Longo TC
- Lundholm JT
- Lázaro-Lobo A
- MacGillavry T
- Mackin CR
- Mahmoud AR
- Manju IA
- Mariën J
- Martínez DN
- Martínez-Bartolomé M
- Meineke EK
- Mendoza-Arroyo W
- Merritt LEL
- Merritt TJS
- Migiani G
- Miles LS
- Minor ES
- Mitchell N
- Mohammadi Bazargani M
- Moles AT
- Monk JD
- Moore CM
- Morales-Morales PA
- Moyers BT
- Munim S
- Munshi-South J
- Murphy SM
- Murúa MM
- Muñoz-Rojas M
- Neila M
- Ness RW
- Nikolaidis O
- Njunjić I
- Nosko P
- Núñez-Farfán J
- Ohgushi T
- Olsen KM
- Opedal ØH
- Ornelas C
- Parachnowitsch AL
- Paratore AS
- Parody-Merino AM
- Paule J
- Paulo OS
- Pena JC
- Peres-Neto PR
- Pfeiffer VW
- Pinho P
- Piot A
- Porth IM
- Poulos N
- Prashad C
- Puentes A
- Qu J
- Quintero-Vallejo E
- Raciti SM
- Raeymaekers JAM
- Raveala KM
- Rennison DJ
- Ribeiro MC
- Richardson JL
- Rivas-Torres G
- Rivera BJ
- Roddy AB
- Rodriguez-Muñoz E
- Román JR
- Rossi LS
- Rowntree JK
- Ryan TJ
- Salinas S
- Sanders NJ
- Santangelo JS
- Santiago-Rosario LY
- Savage AM
- Scheepens JF
- Schilthuizen M
- Schneider AC
- Scholier T
- Scott JL
- Shaheed SA
- Shefferson RP
- Shepard CA
- Shykoff JA
- Silveira G
- Smith AD
- Solis-Gabriel L
- Soro A
- Spellman KV
- Starke-Ottich I
- Stephan JG
- Stephens JD
- Szulc J
- Szulkin M
- Tack AJM
- Tamburrino Í
- Tate TD
- Tergemina E
- Theodorou P
- Thompson KA
- Threlfall CG
- Tinghitella RM
- Toledo-Chelala L
- Tong AT
- Tong X
- Uroy L
- Utsumi S
- Vandegehuchte ML
- VanWallendael A
- Vidal PM
- Wadgymar SM
- Wang A-Y
- Wang N
- Warbrick ML
- Whitney KD
- Whitney KS
- Wiesmeier M
- Wiles JT
- Wu J
- Xirocostas ZA
- Yan Z
- Yao J
- Yoder JB
- Yoshida O
- Zhang J
- Zhao Z
- Ziter CD
- Zuellig MP
- Zufall RA
- Zurita JE
- Zytynska SE
- Álvarez J
- Publication venue
- 'American Association for the Advancement of Science (AAAS)'
- Publication date
- 01/01/2022
- Field of study
Urbanization transforms environments in ways that alter biological evolution. We examined whether urban environmental change drives parallel evolution by sampling 110,019 white clover plants from 6169 populations in 160 cities globally. Plants were assayed for a Mendelian antiherbivore defense that also affects tolerance to abiotic stressors. Urban-rural gradients were associated with the evolution of clines in defense in 47% of cities throughout the world. Variation in the strength of clines was explained by environmental changes in drought stress and vegetation cover that varied among cities. Sequencing 2074 genomes from 26 cities revealed that the evolution of urban-rural clines was best explained by adaptive evolution, but the degree of parallel adaptation varied among cities. Our results demonstrate that urbanization leads to adaptation at a global scale
Multi-messenger observations of a binary neutron star merger
- Author
- Aab A
- Aartsen MG
- Abbott BP
- Abbott R
- Abbott TD
- Abbott TMC
- Abdalla H
- Abe F
- Abeysekara AU
- Abramo LR
- Abramowski A
- Abreu P
- Acernese F
- Acero F
- Ackermann M
- Ackley K
- Ackley K
- Adams C
- Adams J
- Adams SM
- Adams T
- Addesso P
- Adhikari RX
- Adya VB
- Affeldt C
- Afrough M
- Agarwal B
- Agathos M
- Agatsuma K
- Aggarwal N
- Aglietta M
- Agliozzo C
- Agudo I
- Aguiar OD
- Aguilar JA
- Aharonian F
- Ahlers M
- Ahrens M
- Aiello L
- Ain A
- Ajith P
- Akras S
- Al Samarai I
- Albert A
- Albert A
- Albuquerque IFM
- Albury JM
- Alcaniz JS
- Alexander KD
- Alfaro R
- Alighieri S Di Serego
- Allam S
- Allekotte I
- Allen B
- Allen G
- Allison J
- Allison JR
- Allocca A
- Almela A
- Altin PA
- Altmann D
- Alvarez C
- Alvarez JD
- Alvarez M Dovale
- Alvarez-Muiz J
- Amati L
- Amato A
- An T
- Ananyeva A
- Anastasi GA
- Anchordoqui L
- Andeen K
- Anderson JP
- Anderson SB
- Anderson T
- Anderson WG
- Andrada B
- Andre M
- Andreoni I
- Andreoni I
- Andringa S
- Angelova SV
- Anghinolfi M
- Angner EO
- Angus CR
- Annis J
- Ansseau I
- Antier S
- Anton G
- Antonelli LA
- Antonelli LA
- Anupama GC
- Aoki K
- Aoki W
- Appert S
- Aptekar RL
- Arai K
- Arakawa M
- Aramo C
- Araya MC
- Arcavi I
- Arceo R
- Ardid M
- Areeda JS
- Aresu G
- Argan A
- Argelles C
- Arnaud N
- Array LWA Long Wavelength
- Array MWA Murchison Widefield
- Arrieta M
- Arsene N
- Arteaga-Velzquez JC
- Artola R
- Arun KG
- Asakura Y
- Asaoka Y
- Ascenzi S
- Ashall C
- Ashley MCB
- Ashton G
- Asorey H
- Assis P
- Ast M
- Aston SM
- Astone P
- Atallah DV
- ATLAS
- Atwood WB
- Aubert J-J
- Aubert P
- Aublin J
- Auffenberg J
- Aufmuth P
- Aulbert C
- AultONeal K
- Austin C
- Avgitas T
- Avila G
- Avila-Alvarez A
- Awad A Kuotb
- Axani S
- Baar S
- Babak S
- Bachetti M
- Backes M
- Bacon P
- Bader MKM
- Badescu AM
- Bae S
- Bagherpour H
- Bai X
- Bailes M
- Baker PT
- Balaceanu A
- Balanutsa PV
- Balasubramanian A
- Balbinot E
- Baldaccini F
- Baldini L
- Ballardin G
- Ballmer SW
- Bally J
- Balzer A
- Banagiri S
- Banerji M
- Bannister KW
- Barayoga JC
- Barbarino C
- Barbato F
- Barber AS
- Barbiellini G
- Barbiellini G
- Barclay SE
- Baret B
- Barish BC
- Barker D
- Barkett K
- Barnard M
- Barnes J
- Barone F
- Barr B
- Barrios-Marti J
- Barron JP
- Barsotti L
- Barsuglia M
- Barta D
- Barthelmy SD
- Bartlett J
- Bartos I
- Barway S
- Barway S
- Barwick SW
- Basa S
- Bassiri R
- Basti A
- Bastieri D
- Batch JC
- Bauer FE
- Bauer FE
- Baum V
- Bawaj M
- Bay R
- Bayley JC
- Bazzan M
- Bazzano A
- Bchele M
- Beardmore AP
- Beardsley A
- Beatty JJ
- Becerril A
- Becherini Y
- Bechtol K
- Becker KH
- Becsy B
- Beer C
- Bejger M
- Belahcene I
- Belhorma B
- Bell AS
- Bellazzini R
- Bellido JA
- Bellm E
- Belmont-Moreno E
- Benetti S
- Benkhali F Ait
- Benoit-Levy A
- BenZvi SY
- Berat C
- Berenji B
- Berge D
- Berger BK
- Berger E
- Bergmann G
- Berisso M Gomez
- Berley D
- Bernal A
- Bernardini E
- Bernardini MG
- Bernhard S
- Bernrhr K
- Bero JJ
- Beroiz M
- Berry CPL
- Bersanetti D
- Bertaina ME
- Bertin E
- Bertin V
- Bertolini A
- Berton M
- Bertou X
- Bessell MS
- Besson DZ
- Beswick R
- Betzwieser J
- Bhagwat S
- Bhalerao V
- Bhandare R
- Bhattacharya D
- Biagi S
- Biermann PL
- Bilenko IA
- Billingsley G
- Billman CR
- Binder G
- Bindig D
- Birch J
- Birney R
- Birnholtz O
- Biscans S
- Biscoveanu S
- Bisht A
- Bissaldi E
- Bissaldi E
- Biteau J
- Bitossi M
- Biwer C
- Bizouard MA
- Blackburn JK
- Blackburn L
- Blackman J
- Blackwell R
- Blaess SG
- Blagorodnova N
- Blair CD
- Blair DG
- Blair RM
- Blanchard P
- Blanco A
- Bland PA
- Blandford RD
- Blaufuss E
- Blazek J
- Bleve C
- Bloemen S
- Bloom ED
- Blot S
- Bock O
- Bode N
- Boer M
- Bogaert G
- Bohacova M
- Bohe A
- Bohm C
- Boisson C
- Bolmont J
- Bond IA
- Bondu F
- Bonifazi C
- Bonilla E
- Bonino R
- Bonnand R
- Bonnefoy S
- Bonoli S
- Booler T
- Boom BA
- Bordas P
- Bork R
- Bormuth R
- Borner M
- Borodai N
- Bos F
- Boschi V
- Bose D
- Bose S
- Boser S
- Bossie K
- Botner O
- Bottacini E
- Bottcher M
- Botti AM
- Botticella MT
- Bouffanais Y
- Bourbeau E
- Bourbeau J
- Bourret S
- Bouwhuis MC
- Bozzi A
- Bozzo E
- Brack J
- Bradaschia C
- Bradascio F
- Brady PR
- Branchesi M
- Brancus I
- Brandt S
- Brau JE
- Braun J
- Braun J
- Bravo O Martinez
- Brayeur L
- Breeveld AA
- Bregeon J
- Bregeon J
- Brenzke M
- Bretz H-P
- Bretz T
- Briant T
- Bridgeman A
- Briechle FL
- Briggs MS
- Brillet A
- Brinkmann M
- Brisbois C
- Brisson V
- Brnzas H
- Brocato E
- Brockill P
- Broderick JW
- Broida JE
- Bron S
- Brooks AF
- Brooks D
- Brostean-Kaiser J
- Brout D
- Brown DA
- Brown DD
- Brown IS
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- Brunner J
- Bruun SH
- Bryan M
- Buchanan CC
- Buchholz P
- Buckley DAH
- Buckley-Geer E
- Budnev NM
- Buehler R
- Bueno A
- Bufano F
- Buffa F
- Buikema A
- Buitink S
- Bulgarelli A
- Bulger J
- Bulik T
- Bulik T
- Bulla M
- Bulten HJ
- Buonanno A
- Burgay M
- Burgess JM
- Burgman A
- Burhonov O
- Burke DL
- Burns E
- Burrows DN
- Buscemi M
- Buskulic D
- Buson S
- Bustillo J Caldern
- Busto J
- Butler NR
- Butler RE
- Buttu M
- Buy C
- Byer RL
- Caballero-Garcia MD
- Caballero-Mora KS
- Caballero-Mora KS
- Cabero M
- Cabral J
- Caccianiga L
- Cadonati L
- Cagnoli G
- Cahillane C
- Callister TA
- Calloni E
- CALTECH GROWTH JAGWAR
- Cameron RA
- Camilo F
- Camp JB
- Campana S
- Camuccio R
- Cancio A
- Canepa M
- Canfora F
- Canizares P
- Cannella C
- Cannizzaro G
- Cannon KC
- Cano Z
- Cao H
- Cao J
- Cao XL
- Capaccioli M
- Capano CD
- Capasso M
- Capistrn T
- Capocasa E
- Capone A
- Capozzi D
- Cappellaro E
- Caputo R
- Caramete L
- Caraveo P
- Caraveo PA
- Carbognani F
- Carboni G
- Cardenas B Vargas
- Cardillo M
- Caria T
- Caride S
- Carlin JL
- Carney MF
- Caroff S
- Carosi A
- Carr J
- Carramiana A
- Carretti E
- Cartier R
- Caruso R
- Carver T
- Casadio C
- Casado A Lopez
- Casanova S
- Casanova S
- Casasola V
- Casella P
- Casentini C
- Casey J
- Casier M
- Castander FJ
- Castangia P
- Castellina A
- Castellon A
- Castellon JL Nilo
- Castillo J Alvarez
- Castillo M
- Castro JM Gonzalez
- Castro ML Diaz
- Castro-Tirado AJ
- Casu S
- Catalani F
- Cataldi G
- Cattaneo PW
- Caudill S
- Cavagli M
- Cavalier F
- Cavalieri R
- Cavazzuti E
- Cazon L
- Cella G
- Celli S
- Cenko SB
- Cepeda CB
- Cerd-Durn P
- Ceron JM Castro
- Cerretani G
- Cerruti M
- Cerutti AC Cobos
- Cesarini E
- Chakraborty N
- Chamberlin SJ
- Chambers KC
- Chan M
- Chandra P
- Chang S-W
- Chang Z
- Chao S
- Charlton P
- Chase E
- Chassande-Mottin E
- Chatterjee D
- Chatterjee D
- Chatziioannou K
- Chaves RCG
- Chavez AG
- Chavushyan V
- Cheeseboro BD
- Chekhtman A
- Chen A
- Chen G
- Chen HY
- Chen L
- Chen T-W
- Chen TX
- Chen X
- Chen Y
- Chen Y
- Chen YB
- Chen YP
- Chenevez J
- Cheng H-P
- Cherry ML
- Cheung CC
- Cheung E
- Chevalier J
- Chia H
- Chiang J
- Chiarusi T
- Chincarini A
- Chinellato JA
- Chirkin D
- Chiummo A
- Chmiel T
- Cho HS
- Cho M
- Choi C
- Choi J-S
- Chornock R
- Chow JH
- Christensen N
- Christov A
- Chu Q
- Chua AJK
- Chua S
- Chudoba J
- Chung AKW
- Chung S
- Ciani G
- Cikota A
- Ciolfi R
- Ciprini S
- Circella M
- Cirelli CE
- Cirone A
- Clara F
- Clark JA
- Clark K
- Clark P
- Clarke TE
- Classen L
- Clay RW
- Clearwater P
- Cleva F
- Cleveland WH
- Cline T
- Cobb BE
- Cocchieri C
- Coccia E
- Coelho JAB
- Coelho P
- Coenders S
- Cohadon P-F
- Cohen D
- Cohen-Tanugi J
- Colafrancesco S
- Colafrancesco S
- Colalillo R
- Colazo C
- Coleiro A
- Coleman A
- Colla A
- Collaboration ALMA
- Collaboration ANTARES
- Collaboration BOOTES
- Collaboration CALET
- Collaboration DLT40
- Collaboration HAWC
- Collaboration HESS
- Collaboration IceCube
- Collaboration IKI-GW Follow-up
- Collaboration Insight-Hxmt
- Collaboration IPN
- Collaboration KU
- Collaboration LOFAR
- Collaboration MASTER
- Collaboration Pi Sky
- Collaboration Pierre Auger
- Collaboration Swift
- Collaboration VINROUGE
- Collette CG
- Collica L
- Collin GH
- Colmenero E Romero
- Coluccia MR
- Cominsky LR
- Cominsky LR
- Conceicao R
- Concu R
- Condon B
- Coniglione R
- Connaughton V
- Conrad J
- Conrad JM
- Consolati G
- Consortium TZAC
- Constancio M
- Conti L
- Contreras F
- Cook DO
- Cook ER
- Cooke J
- Cooper MJ
- Cooper SJ
- Copperwheat C
- Corban P
- Corbitt TR
- Cordero-Carrion I
- Corley KR
- Cornish N
- Corongiu A
- Corral-Santana JM
- Corsi A
- Cortese S
- Costa CA
- Costa CF Da Silva
- Costa E
- Costa-Duarte MV
- Costantin D
- Costantini H
- Cotti U
- Cotzomi J
- Coughlin M
- Coughlin MW
- Coughlin SB
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- Coulter DA
- Countryman ST
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- Coutu S
- Couvares P
- Covas PB
- Covault CE
- Covino S
- Cowan EE
- Coward DM
- Coward DM
- Cowart MJ
- Cowen DF
- Cowperthwaite P
- Coyle P
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- Coyne R
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- Creighton JDE
- Creighton TD
- Creusot A
- Cripe J
- Crisp H
- Crocce M
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- Cutter R
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- Cwiok M
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- D'Al A
- D'Amico F
- D'Amico S
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- D'Andrea CB
- D'Antonio S
- D'Avanzo P
- D'Elia V
- D'Olivo JC
- Da Costa LN
- Dabrowski R
- Dadina M
- Dal Canton T
- Daniel B
- Danilishin SL
- Danzmann K
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- Dasso S
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- De Carvalho W Rodrigues
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- De Jong M
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- De laurentis M
- De Leon C
- De Leon S Coutio
- De Mauro G
- De Mitri I
- De Naurois M
- de Oliveira C Mendes
- De Oliveira J
- De Oliveira MA Leigui
- de Oliveira R Lopes
- De Palma F
- De Pasquale M
- De Pietri R
- De Ridder S
- De Rosa R
- De Rossi C
- De Souza V
- De Ugarte-Postigo A
- De Varona O
- De Vries KD
- De Wasseige G
- De With M
- De K
- De S
- Debatin J
- Debra D
- Decock J
- Degallaix J
- Deiana GL
- Deil C
- Del Monte E
- Del Pozzo W
- Del Pulgar C Perez
- DeLaunay JJ
- Deleglise S
- Deligny O
- Della Valle M
- Deller AT
- Dembinski H
- Demos N
- Deng JK
- Denker T
- Denneau L
- Dennefeld M
- Dent T
- Depoy DL
- Dergachev V
- DeRosa RT
- Desai S
- DeSalvo R
- Deschamps A
- Desiati P
- Dessart L
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- Devillepoix HAR
- Devin J
- Dewangan GC
- Dewilt P
- DeYoung T
- Dhurandhar S
- Di Fiore L
- Di Giovanni M
- Di Girolamo T
- Di Lalla N
- Di Lieto A
- Di Lorenzo V
- Di Mauro M
- Di Pace S
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- Diaz J Casanueva
- Diaz MC
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- Diaz-Velez JC
- Dichiara S
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- Dobrigkeit C
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- Dolique V
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- Downes TP
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- Piro AL
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- Publication venue
- 'American Astronomical Society'
- Publication date
- 01/01/2017
- Field of study
On 2017 August 17 a binary neutron star coalescence candidate (later designated GW170817) with merger time 12:41:04 UTC was observed through gravitational waves by the Advanced LIGO and Advanced Virgo detectors. The Fermi Gamma-ray Burst Monitor independently detected a gamma-ray burst (GRB 170817A) with a time delay of ~1.7 s with respect to the merger time. From the gravitational-wave signal, the source was initially localized to a sky region of 31 deg2 at a luminosity distance of 40+8-8 Mpc and with component masses consistent with neutron stars. The component masses were later measured to be in the range 0.86 to 2.26 Mo. An extensive observing campaign was launched across the electromagnetic spectrum leading to the discovery of a bright optical transient (SSS17a, now with the IAU identification of AT 2017gfo) in NGC 4993 (at ~40 Mpc) less than 11 hours after the merger by the One- Meter, Two Hemisphere (1M2H) team using the 1 m Swope Telescope. The optical transient was independently detected by multiple teams within an hour. Subsequent observations targeted the object and its environment. Early ultraviolet observations revealed a blue transient that faded within 48 hours. Optical and infrared observations showed a redward evolution over ~10 days. Following early non-detections, X-ray and radio emission were discovered at the transient’s position ~9 and ~16 days, respectively, after the merger. Both the X-ray and radio emission likely arise from a physical process that is distinct from the one that generates the UV/optical/near-infrared emission. No ultra-high-energy gamma-rays and no neutrino candidates consistent with the source were found in follow-up searches. These observations support the hypothesis that GW170817 was produced by the merger of two neutron stars in NGC4993 followed by a short gamma-ray burst (GRB 170817A) and a kilonova/macronova powered by the radioactive decay of r-process nuclei synthesized in the ejecta
Pooled analysis of WHO Surgical Safety Checklist use and mortality after emergency laparotomy
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- Aahlin EK
- Aamer A
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- Magee C
- Maghrabi A
- Maghrabi AA
- Magri D
- Mahanty S
- Maharaj G
- Mahdi A
- Mahdi S
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- Maher ME
- Mahmoud B
- Mahmoud H
- Mahmoud M
- Mahmoud MA
- Mahmoud MI
- Mahmoud S
- Mahmoud SME
- Mahmud K
- Maillot B
- Maimbo M
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- Maison K
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- Mak T
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- Makinde M
- Makupe A
- Malaga B
- Malavenda M
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- Malik P
- Malik TAM
- Mamdouh E
- Mamdouh R
- Manatakis DK
- Manchego Bautista AC
- Manchego Bautista AC
- Manfreda S
- Mangan C
- Mangan C
- Mangiapane M
- Manipal CE
- Maniscalco A
- Mann T
- Mannu GS
- Mano MJB
- Manrique Sila G
- Manrique Sila GC
- Manriquez-Reyes M
- Manrrique Sila G
- Mansor EY
- Mansour B
- Mansour S
- Mansuri A
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- Mapasse D
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- Maraie N
- Marcelo Delgado J
- Marey A
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- Margaritis M
- Maria Garcia-Perez J
- Mariani A
- Marinkovic B
- Marinos C
- Marks E
- Marples L
- Marret J-B
- Marroquin Rodriguez DE
- Marshall DC
- Martian B-V
- Martin A
- Mas R
- Mason C
- Mat TNT
- Mata LPS
- Matheu A
- Mathew SW
- Matos-Puig R
- Mattar O
- Matter SM
- Mauro L
- Mayasari M
- Mazelyte R
- Mazrimas P
- Mazzella A
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- Melo R
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- Mendoza I
- Menegussi J
- Mensah E
- Menshawy A
- Mentula P
- Meqbil J
- Mercado Rodriguez L-A
- Mericliler M
- Merlini D
- Merlini D
- Merlo MS
- Mesbah N
- Meshref A
- Messa Aguilar WL
- Messa Aguilar WL
- Metwally MM
- Migliore M
- Mihaljevic AL
- Mihaljevic AL
- Mihanovic J
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- Mikalauskas S
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- Milligan W
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- Minguez Garcia J
- Minguez G
- Minocha A
- Minocha A
- Miranda C
- Mircea H
- Mirghani D
- Mironescu A
- Mironescu A
- Mironescu AS
- Mironescu AS
- Mirza A
- Mirza S
- Mistry A
- Mitrasinovic S
- Mitroudi M
- Mitroudis N
- Mittal A
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- Miyarde Leon A
- Mizzi C
- Mizzi S
- Mlotshwa M
- Moaty M
- Mochet S
- Modolo MM
- Modolo MM
- Modolo MM
- Moe TT
- Mogan YP
- Moghazy ME
- Mohamed A
- Mohamed A
- Mohamed AM
- Mohamed AR
- Mohamed B
- Mohamed F
- Mohamed I
- Mohamed M
- Mohamed MA
- Mohamed MAEH
- Mohamed MM
- Mohamed O
- Mohamed SR
- Mohameden A
- Mohammad A
- Mohammad A
- Mohammed A
- Mohammed A
- Mohammed AR
- Mohammed H
- Mohammed MM
- Mohammed MMH
- Mohammed S
- Mohan H
- Mohan M
- Mohan M
- Mok YT
- Mokhtar A
- Molina G
- Monaghan E
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- Monrad-Hansen PW
- Monteleone M
- Monteleone M
- Montes I
- Montes I
- Montoya Botero JA
- Montrimaite M
- Montrimaite M
- Moodley Y
- Moore R
- Moore R
- Mora JJV
- Morales C
- Morandi E
- Moreira G
- Moreno SC
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- Morshedy EM
- Morsi A
- Morsi M
- Morton D
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- Morton R
- Mosad A
- Mosalum O
- Mostafa HA
- Mostafa M
- Mostafa M
- Mousa M
- Moussa O
- Moustafa A
- Mouttalib S
- Mowafy B
- Mphatsoe AM
- Mshelbwala P
- Msiska N
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- Mukin ADF
- Muktar U
- Mukuzunga C
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- Munipalle PC
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- Murutoglu B
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- Musowoya J
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- Musyoka CK
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- Mutabazi AZ
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- Mutlu V
- Muzio E
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- Mykoniatis I
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- Nadkarni S
- Naess PA
- Nagy GS
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- Najjar M
- Nanthakumaran S
- Napolitano L
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- Naqvi SA
- Naqvi T
- Naranjo Aristizaibal FA
- Narayanan R
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- Narvestad JK
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- Nashat M
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- Nashidengo P
- Nasir A
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- Nassif D
- Nastri G
- Natalie H
- Nataraja R
- Natili A
- Navarro A
- Nawara C
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- Nayel AR
- Nazir M
- Ndajiwo A
- Ndajiwo A
- Ndegwa W
- Ndlovu SR
- Ndwambi P
- Negida A
- Negoi I
- Nel D
- Nemeth K
- Neo YN
- Neo YT
- Neophytou C
- Nepogodiev D
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- Nepogodiev D
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- Nessa A
- Nestorovic M
- Nevieraite V
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- Ng ZH
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- Ngwa TE
- Niazi AK
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- Niranjan N
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- Niyirera E
- Njokanma I
- Nnajiuba H
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- Nofal E
- Noor F
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- Nouh T
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- Noukpozounkou B
- Novak A
- Nowers J
- Nsengimana VJP
- Nsengiyumva C
- Ntirenganya F
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- Nurqistan HD
- Nwabuoku E
- Nwinee V
- Nwokoro C
- Nyberg J
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- O'Connor T
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- O'neill M
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- Ortega-Vazquez I
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- Palomino Castillo VD
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- Papaskarlatos I-A
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- Patoulias I
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- Pena L
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- Perez Velasquez CI
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- Perino M
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- Pertersen Servin GR
- Pesenti G
- Petrikenas S
- Peycelon M
- Peycelon M
- Pezas T
- Pezas T
- Pezelj N
- Phillips N
- Picardo A
- Picciariello A
- Pimenta ML
- Pineno-Flores C
- Pinkney T
- Pinkney T
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- Pino W
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- Powell A
- Prabhudesai A
- Pranevicius R
- Prasad SS
- Preckailaite E
- Primavesi F
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- Pronin S
- Prudhomme T
- Psaila J
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- Punja V
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- Qaissieh A
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- Qureshi AU
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- Rajmohan S
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- Rakita I
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- Ramarez Cabrera CC
- Ramazzini P
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- Rashad E
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- Rausa E
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- Razek T
- Razi SAU
- Razmdjou S
- Razuri C
- Razzaque J
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- Redota MAP
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- Sahel S
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- Salah OM
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- Samaraweera DI
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- Sandoval Barrantes AM
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- Schultz JK
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- Scott M
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- Semeda N
- Semiz A
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- Senanayake KJ
- Senanayake WSMKJ
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- Sfougaris D
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- Shachykava T
- Shah A
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- Shaharuddin S
- Shahbaz AR
- Shaheen A
- Shahine A
- Shahzad N
- Shaikh N
- Shaikh S
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- Shillito S
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- Snyder E
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- Sobnach S
- Sodde P
- Soeselo DA
- Sokratous A
- Solaini L
- Solar Garcia L
- Solar Garcia L
- Soldevila-Verdeguer C
- Soley R
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- Soliman N
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- Soliman S
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- Sollazzo V
- Soltani N
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- Soulou V
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- Spence R
- Spence R
- Spence R
- Spence R
- Spence R
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- Sproule L
- Spurr M
- Sreedharan A
- Srinivasan R
- Sriram A
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- Sruogiene EZ
- Staerkle RF
- Starr N
- Stasinou T
- Steccanella F
- Stefanopoulos A
- Stephen A
- Stewart D
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- Stuva J
- Styles K
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- Suarez AAB
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- Suleiman SI
- Summerour V
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- Sunderland G
- Sundstrom SM
- Suresh S
- Sutandi N
- Sutanto EPR
- Sutton P
- Sutton P
- Suyadi A
- Swann J
- Swaroop M
- Swaroop M
- Syibrah KZ
- Sykes M
- Szczap A
- Szeto CCL
- Szeto KJ-Y
- Tabiri S
- Tabiri S
- Tabiri S
- Tabiri S
- Tabiri S
- Tabiri S
- Tackie E
- Taddei A
- Tade A
- Tafazal H
- Taha EMS
- Tahboub H
- Taher AA
- Taher M
- Taher MM
- Taieb C
- Taiwo A
- Taiwo O
- Taiwo O
- Talaat M
- Tale F
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- Talukder S
- Talukder S
- Talving P
- Talving P
- Tammam A
- Tan C
- Tan CL
- Tan CY
- Tan JJ
- Tan JK
- Tan KSK
- Tan RCK
- Tan YK
- Tan YW
- Tanase A
- Tanase A
- Tang A
- Tang L
- Tani SI
- Tansoker I
- Tarek A
- Tarek A
- Tarek D
- Targa S
- Tariq S
- Tata MD
- Tatagiba LS
- Tawfik BA
- Tawfik G
- Tawfik G
- Taylor F
- Teasdale E
- Teasdale E
- Teasdale E
- Teasdale E
- Tedeschi U
- Tedjaatmadja C
- Telfah MM
- Tembo T
- Temoche E
- Tennakoon A
- Teo SY
- Ter EZ
- Tessera G
- Teufelberger G
- Tew YY
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- Tewari S
- Th'ng F
- Thabet W
- Thalgaspitiya SPB
- Tham JC
- Thanusan V
- Tharmalingam S
- Theodosopoulos T
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- Thompson B
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- Thorarinsdottir H
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- Timothy OK
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- Todd KO
- Toeema AG
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- Toribio Orbegozo PA
- Torrance HD
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- Toto OF
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- Tselos A
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- Turati L
- Turati L
- Turkustani S
- Turner M
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- Publication venue
- Publication date
- 15/10/2018
- Field of study
Background The World Health Organization (WHO) Surgical Safety Checklist has fostered safe practice for 10 years, yet its place in emergency surgery has not been assessed on a global scale. The aim of this study was to evaluate reported checklist use in emergency settings and examine the relationship with perioperative mortality in patients who had emergency laparotomy. Methods In two multinational cohort studies, adults undergoing emergency laparotomy were compared with those having elective gastrointestinal surgery. Relationships between reported checklist use and mortality were determined using multivariable logistic regression and bootstrapped simulation. Results Of 12 296 patients included from 76 countries, 4843 underwent emergency laparotomy. After adjusting for patient and disease factors, checklist use before emergency laparotomy was more common in countries with a high Human Development Index (HDI) (2455 of 2741, 89.6 per cent) compared with that in countries with a middle (753 of 1242, 60.6 per cent; odds ratio (OR) 0.17, 95 per cent c.i. 0.14 to 0.21, P <0001) or low (363 of 860, 422 per cent; OR 008, 007 to 010, P <0.001) HDI. Checklist use was less common in elective surgery than for emergency laparotomy in high-HDI countries (risk difference -94 (95 per cent c.i. -11.9 to -6.9) per cent; P <0001), but the relationship was reversed in low-HDI countries (+121 (+7.0 to +173) per cent; P <0001). In multivariable models, checklist use was associated with a lower 30-day perioperative mortality (OR 0.60, 0.50 to 073; P <0.001). The greatest absolute benefit was seen for emergency surgery in low- and middle-HDI countries. Conclusion Checklist use in emergency laparotomy was associated with a significantly lower perioperative mortality rate. Checklist use in low-HDI countries was half that in high-HDI countries.Peer reviewe
Effect of alirocumab on mortality after acute coronary syndromes. An analysis of the ODYSSEY OUTCOMES randomized clinical trial
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- Vikman S
- Viktorova I
- Vincendet M
- Violini R
- Vishnevsky AY
- Vizel S
- Vo A
- Voeller H
- Voevoda MI
- Vogel R
- Vohra R
- Vora K
- Voyce S
- Vrolix MCM
- Vulic D
- Vuurmans T
- Wada A
- Waider W
- Waisman GD
- Waites JH
- Wali A
- Walichiewicz PM
- Waltenberger J
- Waltman J
- Wang J
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- Wang J
- Wattanakit K
- Wei M
- Weidinger F
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- Weintraub H
- Weissbrodt M
- Welka S
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- Werner N
- Westbrook M
- Westerhausen D
- Whitaker J
- White HD
- White L
- White M
- Wiersma JJ
- Wilkins G
- Wilkinson P
- Willems FF
- Wilson MD
- Winkelmann B
- Wiseman A
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- Wojewod P
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- Xavier D
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- Xu X
- Xu Y
- Yagensky A
- Yakushin S
- Yan AT-K
- Yan BPY
- Yanez M
- Yang E
- Yang X
- Yang X
- Yao Z
- Yazdani S
- Yerra SK
- Yin W-H
- Yong H
- Yoon JH
- Younis L
- Yu Y
- Yuan Z
- Yusoff K
- Yusoff K
- Zahger D
- Zaidman CJ
- Zainea M
- Zaman A
- Zapata G
- Zdravko B
- Zea Nunez CA
- Zeiher AM
- Zeiher AM
- Zhang R
- Zhang W
- Zhang X
- Zhang Z
- Zhao X
- Zheleznyy V
- Zheng Y
- Zheng Z
- Zhou Y
- Zhu C
- Zhu H
- Zhu J
- Zirlik A
- Zizka J
- Zobouyan I
- Zong W
- Zrazhevsky K
- Zurakowski A
- Zuran I
- Zweiker R
- Publication venue
- 'Ovid Technologies (Wolters Kluwer Health)'
- Publication date
- 04/01/2019
- Field of study
Background: Previous trials of PCSK9 (proprotein convertase subtilisin-kexin type 9) inhibitors demonstrated reductions in major adverse cardiovascular events, but not death. We assessed the effects of alirocumab on death after index acute coronary syndrome. Methods: ODYSSEY OUTCOMES (Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab) was a double-blind, randomized comparison of alirocumab or placebo in 18 924 patients who had an ACS 1 to 12 months previously and elevated atherogenic lipoproteins despite intensive statin therapy. Alirocumab dose was blindly titrated to target achieved low-density lipoprotein cholesterol (LDL-C) between 25 and 50 mg/dL. We examined the effects of treatment on all-cause death and its components, cardiovascular and noncardiovascular death, with log-rank testing. Joint semiparametric models tested associations between nonfatal cardiovascular events and cardiovascular or noncardiovascular death. Results: Median follow-up was 2.8 years. Death occurred in 334 (3.5%) and 392 (4.1%) patients, respectively, in the alirocumab and placebo groups (hazard ratio [HR], 0.85; 95% CI, 0.73 to 0.98; P=0.03, nominal P value). This resulted from nonsignificantly fewer cardiovascular (240 [2.5%] vs 271 [2.9%]; HR, 0.88; 95% CI, 0.74 to 1.05; P=0.15) and noncardiovascular (94 [1.0%] vs 121 [1.3%]; HR, 0.77; 95% CI, 0.59 to 1.01; P=0.06) deaths with alirocumab. In a prespecified analysis of 8242 patients eligible for ≥3 years follow-up, alirocumab reduced death (HR, 0.78; 95% CI, 0.65 to 0.94; P=0.01). Patients with nonfatal cardiovascular events were at increased risk for cardiovascular and noncardiovascular deaths (P<0.0001 for the associations). Alirocumab reduced total nonfatal cardiovascular events (P<0.001) and thereby may have attenuated the number of cardiovascular and noncardiovascular deaths. A post hoc analysis found that, compared to patients with lower LDL-C, patients with baseline LDL-C ≥100 mg/dL (2.59 mmol/L) had a greater absolute risk of death and a larger mortality benefit from alirocumab (HR, 0.71; 95% CI, 0.56 to 0.90; Pinteraction=0.007). In the alirocumab group, all-cause death declined wit h achieved LDL-C at 4 months of treatment, to a level of approximately 30 mg/dL (adjusted P=0.017 for linear trend). Conclusions: Alirocumab added to intensive statin therapy has the potential to reduce death after acute coronary syndrome, particularly if treatment is maintained for ≥3 years, if baseline LDL-C is ≥100 mg/dL, or if achieved LDL-C is low. Clinical Trial Registration: URL: https://www.clinicaltrials.gov. Unique identifier: NCT01663402
Uncultivated microbes in need of their own taxonomy
- Author
- A Caro-Quintero
- A Collingro
- A Oren
- AC Parte
- B Luef
- C Luo
- D Field
- DH Parks
- E Stackebrandt
- E Stackebrandt
- E Stackebrandt
- F Abreu
- G Lavik
- IC Sutcliffe
- J Goris
- KJ Locey
- Konstantinos T Konstantinidis
- KT Konstantinidis
- KT Konstantinidis
- KT Konstantinidis
- KT Konstantinidis
- M Albertsen
- M Ereshefsky
- M Richter
- ML Coleman
- P Yarza
- PD Schloss
- R Amann
- R Rossello-Mora
- R Rossello-Mora
- R Rossello-Mora
- R Rosselló-Móra
- Ramon Rosselló-Móra
- RG Murray
- RG Murray
- Rudolf Amann
- S Glaubitz
- SJ Spencer
- T Ishoey
- V Gaget
- V Salman
- WB Whitman
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Antifungal activity of propolis against Candidaspecies isolated from cases of chronic periodontitis
- Author
- Agüero MB
- Ana Beatriz Sotero SIQUEIRA
- Azevedo RVP
- Bruno César de Vasconcelos GURGEL
- Daugsch A
- Dodwad V
- Ellepola AN
- Favre B
- Ferreira FB
- Furlletti VF
- Guarnelli ME
- Herrera CL
- Koga-Ito CY
- Koo H
- Larissa Rodrigues Nolasco de Araújo RODRIGUEZ
- Mello BCBS
- Oliveira AC
- Ota C
- Pizzo G
- Pizzo G
- Pusateri CR
- Quintero-Mora ML
- Raniel Fernandes PEIXOTO
- Ricardo Romulo Batista MARINHO
- Ruth Karine Barroso SANTOS
- Salim N
- Sawaya AC
- Sforcin JM
- Sheila ABREU
- Sherf A
- Shokri H
- Siqueira AB
- Tamai R
- Trusheva B
- Yang YL
- Yucesoy M
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
In vitro antimicrobial assessment of Cuban propolis extracts
- Author
- Ayres DC
- Bankova V
- Banskota AH
- Bonvehi JS
- Buckner FS
- Cos P
- Cuesta-Rubio O
- Dantas AP
- Dota KF
- Duran G
- Duran N
- Flegr J
- Flegr J
- Ghasem YB
- Gispert E
- Greenaway W
- Hirumi H
- Ingrid Márquez Hernandez
- Jorge Fraga
- Khaomek P
- Kleich Pérez
- Ledón N
- Li F
- Lianet Monzote
- Lotfy M
- Louis Maes
- Makler MT
- Marcucci MC
- Marquéz I
- Mercedes Campo Fernandez
- Miyares C
- Monique Kerstens
- Monzote L
- Newmann DJ
- Osmany Cuesta-Rubio
- Paul Cos
- Pavlicek A
- Peterson G
- Popolo A
- Quintana JC
- Quintana TJ
- Quintero-Mora ML
- Räz B
- Salomão K
- Santana E
- Sartorelli P
- Sneath PHA
- Takahashi M
- Taylor PL
- Topalkara A
- Trager W
- Ugur A
- Umthong S
- Umthong S
- Ziegler HL
- Publication venue
- Instituto Oswaldo Cruz, Ministério da Saúde
- Publication date
- 01/01/2012
- Field of study
Propolis is a resinous mixture of different plant exudates collected by honeybees. Currently, propolis is widely used as a food supplement and in folk medicine. We have evaluated 20 Cuban propolis extracts of different chemical types, brown (BCP), red and yellow (YCP), with respect to their in vitro antibacterial, antifungal and antiprotozoal properties. The extracts inhibited the growth of Staphylococcus aureus and Trichophyton rubrum at low µg/mL concentrations, whereas they were not active against Escherichia coli and Candida albicans. The major activity of the extracts was found against the protozoa Leishmania, Trypanosoma and Plasmodium, although cytotoxicity against MRC-5 cells was also observed. The BCP-3, YCP-39 and YCP-60 extracts showed the highest activity against P. falciparum, with 50% of microbial growth (IC50) values of 0.2 µg/mL. A positive correlation between the biological activity and the chemical composition was observed for YCP extracts. The most promising antimicrobial activity corresponds to YCP subtype B, which contains acetyl triterpenes as the main constituents. The present in vitro study highlights the potential of propolis against protozoa, but further research is needed to increase selectivity towards the parasite. The observed chemical composition-activity relationship of propolis can contribute to the identification of the active principles and standardisation of this bee product