701 research outputs found
Locally erasable couplers for optical device testing in silicon on insulator
Wafer scale testing is critical to reducing production costs and increasing production yield. Here we report a method that allows testing of individual optical components within a complex optical integrated circuit. The method is based on diffractive grating couplers, fabricated using lattice damage induced by ion implantation of germanium. These gratings can be erased via localised laser annealing, which is shown to reduce the outcoupling efficiency by over 20 dB after the device testing is completed. Laser annealing was achieved by employing a CW laser, operating at visible wavelengths thus reducing equipment costs and allowing annealing through thick oxide claddings. The process used also retains CMOS compatibility
Estudios de la climatologĂa en Quintana Roo (MĂ©xico) y su posible correlaciĂłn con el consumo de energĂa elĂ©ctrica (Parte II)
CIES2020 - XVII Congresso IbĂ©rico e XIII Congresso Ibero-americano de Energia SolarRESUMEN: El desarrollo de este artĂculo es sobre el estudio climatolĂłgico de diez zonas en las cosas del estado de Quintana Roo, en el Caribe Mexicano, El objetivo de este trabajo es analizar el comportamiento de los cambios ambientales observados recientemente en el Caribe, asĂ como los rĂĄpidos aumentos en las temperaturas de la superficie del mar y que se atribuyen al calentamiento global, ademĂĄs el anĂĄlisis de los consumos de energĂa elĂ©ctrica en las zonas estudiadas. Los datos de temperatura han sido recolectados de diez estaciones meteorolĂłgicas en un periodo de 1990 al 2018, asĂ mismo, se han obtenido los datos de consumo de energĂa elĂ©ctrica, en un periodo de 2002 al 2017, con ello se pretende buscar si existe asociaciĂłn entre las dos variables, ademĂĄs, con el conjunto de datos se va a comprobar con la prueba de ajuste de bondad Chi cuadrada si son estadĂsticamente significativos o no significativos, es decir, la cual nos demuestra que las variables disponibles representan razonablemente los datos que uno esperarĂa encontrar. Finalmente, en este trabajo se realizarĂĄn los mapas correspondientes para el anĂĄlisis estadĂstico de las variables de temperatura durante un periodo de 1990 hasta 2018.ABSTRACT: The development of this article is about the climatological study of ten zones in the things of the state of Quintana Roo, in the Mexican Caribbean, The objective of this work is to analyze the behavior of the environmental changes recently observed in the Caribbean, as well as the rapid increases in sea surface temperatures attributed to global warming, in addition to the analysis of electrical energy consumption in the areas studied. The temperature data have been collected from ten meteorological stations in a period from 1990 to 2018, likewise, the data on electricity consumption have been obtained, in a period from 2002 to 2017, with this it is intended to find if there is an association between The two variables, in addition, with the data set, it will be verified with the Chi-square goodness adjustment test if they are statistically significant or not significant, that is, which shows us that the available variables reasonably represent the data that one would expect find. Finally, in this work the corresponding maps will be made for the statistical analysis of the temperature variables during a period from 1990 to 2018.info:eu-repo/semantics/publishedVersio
Cancer chemotherapy in early life significantly alters the maturation of pain processing
Advances in paediatric cancer treatment have led to a ten year survival rate greater than 75%. Platinum-based chemotherapies (e.g.cisplatin) induce peripheral sensory neuropathy in adult and paedriatric cancer patients. The period from birth through to adulthood represents a period of maturation within nociceptive systems. Here we investigated how cisplatin impacts upon postnatal maturation of nociceptive systems. Neonatal Wistar rats (Postnatal day (P) 7) were injected (i.p.) daily with either vehicle (PBS) or cisplatin (1mg/kg) for five consecutive days. Neither group developed mechanical or thermal hypersensitivity immediately during or after treatment. At P22 the cisplatin group developed mechanical (P<0.05) and thermal (P<0.0001) hypersensitivity versus vehicle group. Total DRG or dorsal horn neuronal number did not differ at P45, however there was an increase in intraepidermal nerve fibre density in cisplatin treated animals at this age. The percentage of IB4+ve, CGRP+ve and NF200+ve DRG neurons was not different between groups at P45. There was an increase in TrkA+ve DRG neurons in the cisplatin group at P45, in addition to increased TrkA, NF200 and vGLUT2 immunoreactivity in the lumbar dorsal horn versus controls. These data highlight the impact paediatric cancer chemotherapy has upon the maturation of pain pathways and later life pain experience
Light propagation in statistically homogeneous and isotropic universes with general matter content
We derive the relationship of the redshift and the angular diameter distance
to the average expansion rate for universes which are statistically homogeneous
and isotropic and where the distribution evolves slowly, but which have
otherwise arbitrary geometry and matter content. The relevant average expansion
rate is selected by the observable redshift and the assumed symmetry properties
of the spacetime. We show why light deflection and shear remain small. We write
down the evolution equations for the average expansion rate and discuss the
validity of the dust approximation.Comment: 42 pages, no figures. v2: Corrected one detail about the angular
diameter distance and two typos. No change in result
Flares, wind and nebulae: the 2015 December mini-outburst of V404 Cygni
After more than 26 years in quiescence, the black hole transient V404 Cyg went into a luminous outburst in June 2015, and additional activity was detected in late December of the same year. Here, we present an optical spectroscopic follow-up of the December mini-outburst, together with X-ray, optical and radio monitoring that spanned more than a month. Strong ïŹares with gradually increasing intensity are detected in the three spectral ranges during the ⌠10 days following the Swift trigger. Our optical spectra reveal the presence of a fast outïŹowing wind, as implied by the detection of a P-Cyg proïŹle (He iâ5876 ËA) with a terminal velocity of ⌠2500 kmsâ1 . Nebularlike spectra â with an H α equivalent width of ⌠500 ËA â are also observed. All these features are similar to those seen during the main June 2015 outburst. Thus, the fast optical wind simultaneous with the radio jet is most likely present in every V404 Cyg outburst. Finally, we report on the detection of a strong radio ïŹare in late January 2016, when X-ray and optical monitoring had stopped due to Sun constraints
COVID-19 and stem cell transplantation; results from an EBMT and GETH multicenter prospective survey
Altres ajuts: British Society for Blood and Marrow Transplantation and Cellular Therapy (BSBMTCT); UK NIHR Imperial College Biomedical Research Centre.This study reports on 382 COVID-19 patients having undergone allogeneic (n = 236) or autologous (n = 146) hematopoietic cell transplantation (HCT) reported to the European Society for Blood and Marrow Transplantation (EBMT) or to the Spanish Group of Hematopoietic Stem Cell Transplantation (GETH). The median age was 54.1 years (1.0-80.3) for allogeneic, and 60.6 years (7.7-81.6) for autologous HCT patients. The median time from HCT to COVID-19 was 15.8 months (0.2-292.7) in allogeneic and 24.6 months (â0.9 to 350.3) in autologous recipients. 83.5% developed lower respiratory tract disease and 22.5% were admitted to an ICU. Overall survival at 6 weeks from diagnosis was 77.9% and 72.1% in allogeneic and autologous recipients, respectively. Children had a survival of 93.4%. In multivariate analysis, older age (p = 0.02), need for ICU (p < 0.0001) and moderate/high immunodeficiency index (p = 0.04) increased the risk while better performance status (p = 0.001) decreased the risk for mortality. Other factors such as underlying diagnosis, time from HCT, GVHD, or ongoing immunosuppression did not significantly impact overall survival. We conclude that HCT patients are at high risk of developing LRTD, require admission to ICU, and have increased mortality in COVID-19
Effect of breed type and ionophore supplementation on growth and carcass characteristic in feedlot hair lambs
Anisotropic flow of charged hadrons, pions and (anti-)protons measured at high transverse momentum in Pb-Pb collisions at TeV
The elliptic, , triangular, , and quadrangular, , azimuthal
anisotropic flow coefficients are measured for unidentified charged particles,
pions and (anti-)protons in Pb-Pb collisions at TeV
with the ALICE detector at the Large Hadron Collider. Results obtained with the
event plane and four-particle cumulant methods are reported for the
pseudo-rapidity range at different collision centralities and as a
function of transverse momentum, , out to GeV/.
The observed non-zero elliptic and triangular flow depends only weakly on
transverse momentum for GeV/. The small dependence
of the difference between elliptic flow results obtained from the event plane
and four-particle cumulant methods suggests a common origin of flow
fluctuations up to GeV/. The magnitude of the (anti-)proton
elliptic and triangular flow is larger than that of pions out to at least
GeV/ indicating that the particle type dependence persists out
to high .Comment: 16 pages, 5 captioned figures, authors from page 11, published
version, figures at http://aliceinfo.cern.ch/ArtSubmission/node/186
Centrality dependence of charged particle production at large transverse momentum in Pb-Pb collisions at TeV
The inclusive transverse momentum () distributions of primary
charged particles are measured in the pseudo-rapidity range as a
function of event centrality in Pb-Pb collisions at
TeV with ALICE at the LHC. The data are presented in the range
GeV/ for nine centrality intervals from 70-80% to 0-5%.
The Pb-Pb spectra are presented in terms of the nuclear modification factor
using a pp reference spectrum measured at the same collision
energy. We observe that the suppression of high- particles strongly
depends on event centrality. In central collisions (0-5%) the yield is most
suppressed with at -7 GeV/. Above
GeV/, there is a significant rise in the nuclear modification
factor, which reaches for GeV/. In
peripheral collisions (70-80%), the suppression is weaker with almost independently of . The measured nuclear
modification factors are compared to other measurements and model calculations.Comment: 17 pages, 4 captioned figures, 2 tables, authors from page 12,
published version, figures at
http://aliceinfo.cern.ch/ArtSubmission/node/284
Measurement of the polarisation of W bosons produced with large transverse momentum in pp collisions at sqrt(s) = 7 TeV with the ATLAS experiment
This paper describes an analysis of the angular distribution of W->enu and
W->munu decays, using data from pp collisions at sqrt(s) = 7 TeV recorded with
the ATLAS detector at the LHC in 2010, corresponding to an integrated
luminosity of about 35 pb^-1. Using the decay lepton transverse momentum and
the missing transverse energy, the W decay angular distribution projected onto
the transverse plane is obtained and analysed in terms of helicity fractions
f0, fL and fR over two ranges of W transverse momentum (ptw): 35 < ptw < 50 GeV
and ptw > 50 GeV. Good agreement is found with theoretical predictions. For ptw
> 50 GeV, the values of f0 and fL-fR, averaged over charge and lepton flavour,
are measured to be : f0 = 0.127 +/- 0.030 +/- 0.108 and fL-fR = 0.252 +/- 0.017
+/- 0.030, where the first uncertainties are statistical, and the second
include all systematic effects.Comment: 19 pages plus author list (34 pages total), 9 figures, 11 tables,
revised author list, matches European Journal of Physics C versio
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