105 research outputs found
Multigrid Monte Carlo Algorithms for SU(2) Lattice Gauge Theory: Two versus Four Dimensions
We study a multigrid method for nonabelian lattice gauge theory, the time
slice blocking, in two and four dimensions. For SU(2) gauge fields in two
dimensions, critical slowing down is almost completely eliminated by this
method. This result is in accordance with theoretical arguments based on the
analysis of the scale dependence of acceptance rates for nonlocal Metropolis
updates. The generalization of the time slice blocking to SU(2) in four
dimensions is investigated analytically and by numerical simulations. Compared
to two dimensions, the local disorder in the four dimensional gauge field leads
to kinematical problems.Comment: 24 pages, PostScript file (compressed and uuencoded), preprint
MS-TPI-94-
Quadrupole Pairing Interaction and Signature Inversion
The signature inversion in the \pi h11/2 \otimes \nu h11/2 rotational bands
of odd-odd Cs and La isotopes and the \pi h11/2 \otimes \nu i13/2 bands of
odd-odd Tb, Ho and Tm nuclei is investigated using pairing and deformation self
consistent mean field calculations. The model can rather satisfactorily account
for the anomalous signature splitting, provided that spin assignments in som of
the bands are revised. Our calculations show that signature inversioncan appear
already at axially symmetric shapes. It is found that this is due to the
contribution of the \lambda\mu=22 component of the quadrupole pairing
interaction to the mean field potential.Comment: 17 pages, 14 figures, Nuclear Physics A in prin
On Classification of N=2 Supersymmetric Theories, (e-mail uncorrupted version)
We find a relation between the spectrum of solitons of massive quantum
field theories in and the scaling dimensions of chiral fields at the
conformal point. The condition that the scaling dimensions be real imposes
restrictions on the soliton numbers and leads to a classification program for
symmetric conformal theories and their massive deformations in terms of a
suitable generalization of Dynkin diagrams (which coincides with the A--D--E
Dynkin diagrams for minimal models). The Landau-Ginzburg theories are a proper
subset of this classification. In the particular case of LG theories we relate
the soliton numbers with intersection of vanishing cycles of the corresponding
singularity; the relation between soliton numbers and the scaling dimensions in
this particular case is a well known application of Picard-Lefschetz theory.Comment: 116 pages, HUTP-92/A064 and SISSA-203/92/E
Desenvolvimento de uma prova de imunoadsorção enzimática para detecção de anticorpos contra Babesia bovis
To what extent do frameworks of reading development and the phonics screening check support the assessment of reading development in England?
The purpose of this article is to question the suitability of the phonics screening check in relation to models and theories of reading development. The article questions the appropriateness of the check by drawing on theoretical frameworks which underpin typical reading development. I examine the Simple View of Reading developed by Gough and Tunmer and Ehri’s model of reading development. The article argues that the assessment of children’s development in reading should be underpinned and informed by a developmental framework which identifies the sequential skills in reading development
Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants
Prostate cancer is a polygenic disease with a large heritable component. A number of common, low-penetrance prostate cancer risk loci have been identified through GWAS. Here we apply the Bayesian multivariate variable selection algorithm JAM to fine-map 84 prostate cancer susceptibility loci, using summary data from a large European ancestry meta-analysis. We observe evidence for multiple independent signals at 12 regions and 99 risk signals overall. Only 15 original GWAS tag SNPs remain among the catalogue of candidate variants identified; the remainder are replaced by more likely candidates. Biological annotation of our credible set of variants indicates significant enrichment within promoter and enhancer elements, and transcription factor-binding sites, including AR, ERG and FOXA1. In 40 regions at least one variant is colocalised with an eQTL in prostate cancer tissue. The refined set of candidate variants substantially increase the proportion of familial relative risk explained by these known susceptibility regions, which highlights the importance of fine-mapping studies and has implications for clinical risk profiling. © 2018 The Author(s).Prostate cancer is a polygenic disease with a large heritable component. A number of common, low-penetrance prostate cancer risk loci have been identified through GWAS. Here we apply the Bayesian multivariate variable selection algorithm JAM to fine-map 84 prostate cancer susceptibility loci, using summary data from a large European ancestry meta-analysis. We observe evidence for multiple independent signals at 12 regions and 99 risk signals overall. Only 15 original GWAS tag SNPs remain among the catalogue of candidate variants identified; the remainder are replaced by more likely candidates. Biological annotation of our credible set of variants indicates significant enrichment within promoter and enhancer elements, and transcription factor-binding sites, including AR, ERG and FOXA1. In 40 regions at least one variant is colocalised with an eQTL in prostate cancer tissue. The refined set of candidate variants substantially increase the proportion of familial relative risk explained by these known susceptibility regions, which highlights the importance of fine-mapping studies and has implications for clinical risk profiling. © 2018 The Author(s).Peer reviewe
Search for new phenomena in monophoton final states in proton-proton collisions at root s=8 TeV
Peer reviewe
Avaliação cintilográfica de diferentes dosagens de Tecnécio-99m na padronização da perfusão pulmonar em cães da raça Rottweiller
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