107 research outputs found

    Listening to Luddites: Innovation Antibodies and Corporate Success

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    Protracted innovation is an essential activity of every organization in the modern global marketplace and is fueled by a continuous stream of fresh ideas. Contemporary business literature decries the innovation antibody, employees who intentionally thwart the acquisition and dissemination of crucial new ideas. The business press posits but one uniform type of innovation antibody often unwittingly encouraged by corporate actions, and should be quickly and effectively neutralized. This paper asserts that, like biological antibodies in the human body, the work of innovation antibodies in the corporate body can be either positive or negative. It is true that recalcitrant negative innovation antibodies determined to slow or eliminate innovation must be excised from the organization. Positive innovation antibodies are important to organizational sensemaking and innovation activities, and should not be suppressed or overcome. A revised innovation sequencing model is put forth to guide the activities of positive innovation antibodies, as are specific actions recommended for organizations to encourage the appropriate growth and use of positive innovation antibodies to effect corporate innovation success.innovation; innovation antibodies; sensemaking; strategy; sustainability; values.

    Extreme Diversity

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    During the past decade, most corporations have made considerable efforts to become more efficient, or “better.” Frenzied global competition and the recent economic downturn have revealed that efficiency efforts have limitations, and corporations must also become “different.” That difference is their capacity to innovate. Innovation is based on a continuous stream of new and fresh ideas that come from a diverse cadre of employees. Corporations historically have believed that a uniform workforce promotes harmony, unity, and efficiency, and have relied on homosocial reproduction and innovation antibodies to maintain the traditional corporate trajectory. This paper contends that the scope of diversity present in a corporation’s employee base and the volume of valuable innovative ideas bubbling up from inside the company are correlated. In order to more fully leverage the broad expertise of an intentionally diverse workforce, organizations may wish to consider reorganization, refocusing compensation from individuals to teams, and expanding institutional learning programs. To effectively lead an appropriately diverse organization, executives must provide clear objectives supported by simple metrics, encourage employees to focus their extraordinary capabilities on customers and on worthwhile experiments to ascertain customer needs, and to channel and productively use creative abrasion that naturally occurs between talented people to propel corporate innovation.diversity; extreme diversity; innovation; homosocial reproduction; innovation antibodies.

    The Practice of Telecommuting: A Fresh Perspective

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    Telecommuting has been a popular practice for an increasing number of firms and governmental bodies over the past decade or more. This research paper reviews antecedents, implementation considerations, known consequences, barriers, and recommendations that need to be determined prior to the adoption of telecommuting practices. The paper demonstrates that the phenomenon of telecommuting is the result of historical, sociological, and technological shifts and advancements. While firms have successfully implemented various elements of telecommuting practices, challenges along the way have yielded insights and lessons that merit further examination and discussion. This paper asserts that with selected individuals, proper structure, and sufficient feedback mechanisms in place, the adoption of telecommuting has the capacity to strengthen a firm’s bottom line and provide tangible benefit for its employees. As a case in point, online learning, developed in parallel with the growth of telecommuting, yields substantial benefits for employees and the companies in which they serve. For employees, online learning is convenient, accommodates multiple learning styles, and is an engaging learning mechanism. For corporations, online learning encourages cost-effectiveness, uniformity in quality and flexibility, and enhanced cross-cultural and cross-disciplinary communications, all necessary to meet the challenges of the ever-changing global marketplace.telecommuting; technology; online learning; social media; innovation; institutional learning; cross-cultural communications.

    Development of a Diagnostic Test Set to Assess Agreement in Breast Pathology: Practical Application of the Guidelines for Reporting Reliability and Agreement Studies (GRRAS)

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    Diagnostic test sets are a valuable research tool that contributes importantly to the validity and reliability of studies that assess agreement in breast pathology. In order to fully understand the strengths and weaknesses of any agreement and reliability study, however, the methods should be fully reported. In this paper we provide a step-by-step description of the methods used to create four complex test sets for a study of diagnostic agreement among pathologists interpreting breast biopsy specimens. We use the newly developed Guidelines for Reporting Reliability and Agreement Studies (GRRAS) as a basis to report these methods

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/48157/1/261_2005_Article_BF01887810.pd

    Vitamin D intake is associated with insulin sensitivity in African American, but not European American, women

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    <p>Abstract</p> <p>Background</p> <p>The prevalence of type 2 diabetes is higher among African Americans (AA) vs European Americans (EA), independent of obesity and other known confounders. Although the reason for this disparity is not known, it is possible that relatively low levels of vitamin D among AA may contribute, as vitamin D has been positively associated with insulin sensitivity in some studies. The objective of this study was to test the hypothesis that dietary vitamin D would be associated with a robust measure of insulin sensitivity in AA and EA women.</p> <p>Methods</p> <p>Subjects were 115 African American (AA) and 137 European American (EA) healthy, premenopausal women. Dietary intake was determined with 4-day food records; the insulin sensitivity index (S<sub>I</sub>) with a frequently-sampled intravenous glucose tolerance test and minimal modeling; the Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) with fasting insulin and glucose; and body composition with dual-energy X-ray absorptiometry.</p> <p>Results</p> <p>Vitamin D intake was positively associated with S<sub>I </sub>(standardized β = 0.18, <it>P </it>= 0.05) and inversely associated with HOMA-IR (standardized β = -0.26, <it>P </it>= 0.007) in AA, and the relationships were independent of age, total body fat, energy intake, and % kcal from fat. Vitamin D intake was not significantly associated with indices of insulin sensitivity/resistance in EA (standardized β = 0.03, <it>P </it>= 0.74 and standardized β = 0.02, <it>P </it>= 0.85 for S<sub>I </sub>and HOMA-IR, respectively). Similar to vitamin D, dietary calcium was associated with S<sub>I </sub>and HOMA-IR among AA but not EA.</p> <p>Conclusions</p> <p>This study provides novel findings that dietary vitamin D and calcium were independently associated with insulin sensitivity in AA, but not EA. Promotion of these nutrients in the diet may reduce health disparities in type 2 diabetes risk among AA, although longitudinal and intervention studies are required.</p

    Large expert-curated database for benchmarking document similarity detection in biomedical literature search

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    Document recommendation systems for locating relevant literature have mostly relied on methods developed a decade ago. This is largely due to the lack of a large offline gold-standard benchmark of relevant documents that cover a variety of research fields such that newly developed literature search techniques can be compared, improved and translated into practice. To overcome this bottleneck, we have established the RElevant LIterature SearcH consortium consisting of more than 1500 scientists from 84 countries, who have collectively annotated the relevance of over 180 000 PubMed-listed articles with regard to their respective seed (input) article/s. The majority of annotations were contributed by highly experienced, original authors of the seed articles. The collected data cover 76% of all unique PubMed Medical Subject Headings descriptors. No systematic biases were observed across different experience levels, research fields or time spent on annotations. More importantly, annotations of the same document pairs contributed by different scientists were highly concordant. We further show that the three representative baseline methods used to generate recommended articles for evaluation (Okapi Best Matching 25, Term Frequency-Inverse Document Frequency and PubMed Related Articles) had similar overall performances. Additionally, we found that these methods each tend to produce distinct collections of recommended articles, suggesting that a hybrid method may be required to completely capture all relevant articles. The established database server located at https://relishdb.ict.griffith.edu.au is freely available for the downloading of annotation data and the blind testing of new methods. We expect that this benchmark will be useful for stimulating the development of new powerful techniques for title and title/abstract-based search engines for relevant articles in biomedical research.Peer reviewe
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