Typology of the antegonial notch in the human mandible

Background: Surgical treatment for serious malocclusions and fractures of the organ of mastication is a golden standard in medicine. Procedures performed on the mandible require detailed knowledge of the anatomy of the organ. Antegonial notching constitutes a serious technical challenge for surgeons. Therefore, a detailed anatomical description of this structure, which is the subject of this paper, is essential. Materials and methods: We analysed 251 human Caucasian mandibles of identified sex and took measurements of all sections describing the mandibular antegonial notch. Depending on the proportion between sections we classified the shape of the antegonial notch into three types. The surface area of the notch was calculated. We analysed the dimorphic and bilateral differences for each of the three types of notch. We used variance analysis for the assessment of statistical difference. Results: The analysis revealed that in both men and women, regardless of body side, the type 3 antegonial notch was the most frequent. Type 3 occurred with a frequency of between 38% in men on the right side and 55.9% in women on the left side of the body. Type 1 was the least frequent. Dimorphic differences in the presence of individual types of antegonial notch were statistically significant only for the left side of the body. The symmetrical type (type 2) occurred more frequently in men (by 11%) than in women. Type 3 was found more frequently in women (by 10%) than in men. Bilateral differences in men were revealed for the frequencies of types 1 and 3. On the right side type 1 was more frequent (by 8%), and on the left side type 3 was also more frequent (by 8%). The greatest surface area was found for the asymmetrical posterior type (type 1). The smallest surface area was found for the asymmetrical anterior type 3. This difference was statistically significant with respect to the surface area of types 1 and type 2 and found for both sexes for both sides of the body. However, no statistically significant differences were found between the surface areas of types 1 or 2. Conclusions: Knowledge of the preangular notch anatomy can be useful for surgeons during reconstructive and plastic procedures on the body of the mandible

Detection of SNPs in FABP4 Gene and Its Relationship with Milk Quality Traits in Iraqi Jenoubi Cows

Jenoubi cattle breed classified as a Bos indicus L., is one of Iraqi indigenous cattle that kept for milk production purpose, but the influence of fatty acid-binding protein 4 (FABP4) on milk-related traits remain poorly understood. The current study was conducted to investigate the effect of single nucleotide polymorphisms (SNPs) in the FABP4 gene of Jenoubi cows. The DNA samples were extracted from the blood of 21 cows. Along 565-bp nucleotide (nt) amplicon from the intron 2- exon 3- intron 3 of FABP4 was amplified by polymerase chain reaction (PCR) while forward sequencing was used to detect SNPs and results were analyzed using bioinformatics software. The findings resulted the existence of two SNPs (c.3689G>A and c.3709G>C) in the exon 3 and four SNPs (g.3494A>C, g.3531A>T, g.3743T>C and g.3765T>C) in the intron regions. Therefore, three haplotypes of FABP4 gene were obtained in this study based on three SNPs of g.3494A>C, g.3531A>T and g.3765T>C. Nonetheless, those haplotypes were not significantly influencing to the milk quality traits of Jenoubi cows. However, the SNPs examined in this study might not be used as potential DNA marker to improve milk production traits of the current breed

Analysing the impact of compaction of soil aggregates using X-ray microtomography and water flow simulations

Soil aggregates are structural units of soil, which create complex pore systems controlling gas and water storage and fluxes in soil. Aggregates can be destroyed during swelling and shrinking or by external forces like mechanical compaction and yet, the knowledge of how physical impact alters aggregate structure remains limited. The aim of the study was to quantify the impact of compaction on macroaggregates, mainly on the pore size distribution and water flow. In this study, aggregates (2–5 mm) were collected by dry sieving in grassland of the Fuchsenbigl–Marchfeld Critical Zone Observatory (Austria). The structural alterations of these soil aggregates under controlled compaction were investigated with a non-invasive 3D X-ray microtomography (XMT). The detailed changes in pore size distribution between aggregates (interpores, diameter >90 μm) and within the aggregates (intrapores, diameter ≤90 μm) in pre- and post-compacted soils were revealed at two soil moisture (9.3% and 18.3% w/w) and two bulk density increments (0.28 and 0.71 g cm−3 from the initial values). The soil permeability was simulated using lattice Boltzmann method (LBM) based on 3D images. Soil compaction significantly reduced total pores volume and the proportion of interpores volume and surface area, while total pore surface area and the proportion of intrapores volume and surface area increased. The increases in soil moisture tended to reduce the effects of compaction on interpores and intrapores, while the high compaction increment drastically changed the pore size distribution. The aggregate compaction decreased water penetration potential due to the increase of small intra-aggregate pores and cavities as demonstrated by LBM. Notably, the LBM results showed a significant linear correlation between the water flow rate and bulk density of soil aggregates and predicted that the water flow could be reduced by up to 97–99% at bulk density of ≥1.6 g cm−3 with soil water content of 18.3% w/w. Thus, a combination of imaging and modelling provided new insights on the compaction effects on aggregates, underpinning the importance of protecting soil structure from mechanical compaction to minimise environmental impacts of soil compaction and maintain water infiltration and percolation in arable soils

Primary undifferentiated embryonal sarcoma of the liver mistaken for hydatid disease

Primary undifferentiated embryonal sarcoma of the liver is a rare tumor with a peak incidence between the ages of 6 and 10 years. We report a case of a primary hepatic undifferentiated embryonal sarcoma arising in a 21-year-old male mistaken for hydatid disease of the liver. The rapid recurrence of this tumor along the site of attempted percutaneous drainage illustrates some important management points regarding this malignancy

Search for chargino-neutralino production with mass splittings near the electroweak scale in three-lepton final states in √s=13 TeV pp collisions with the ATLAS detector

A search for supersymmetry through the pair production of electroweakinos with mass splittings near the electroweak scale and decaying via on-shell W and Z bosons is presented for a three-lepton final state. The analyzed proton-proton collision data taken at a center-of-mass energy of √s=13  TeV were collected between 2015 and 2018 by the ATLAS experiment at the Large Hadron Collider, corresponding to an integrated luminosity of 139  fb−1. A search, emulating the recursive jigsaw reconstruction technique with easily reproducible laboratory-frame variables, is performed. The two excesses observed in the 2015–2016 data recursive jigsaw analysis in the low-mass three-lepton phase space are reproduced. Results with the full data set are in agreement with the Standard Model expectations. They are interpreted to set exclusion limits at the 95% confidence level on simplified models of chargino-neutralino pair production for masses up to 345 GeV

Simulation of resonant tunneling heterostructures: numerical comparison of a complete Schr{ö}dinger-Poisson system and a reduced nonlinear model

Two different models are compared for the simulation of the transverse electronic transport through an heterostructure: a $1D$ self-consistent Schr{ö}dinger-Poisson model with a numerically heavy treatment of resonant states and a reduced model derived from an accurate asymptotic nonlinear analysis. After checking the agreement at the qualitative and quantitative level on quite well understood bifurcation diagrams, the reduced model is used to tune double well configurations for which nonlinearly interacting resonant states actually occur in the complete self-consistent model

Search for direct stau production in events with two hadronic tau-leptons in root s=13 TeV pp collisions with the ATLAS detector

A search for the direct production of the supersymmetric partners ofτ-leptons (staus) in final stateswith two hadronically decayingτ-leptons is presented. The analysis uses a dataset of pp collisions corresponding to an integrated luminosity of139fb−1, recorded with the ATLAS detector at the LargeHadron Collider at a center-of-mass energy of 13 TeV. No significant deviation from the expected StandardModel background is observed. Limits are derived in scenarios of direct production of stau pairs with eachstau decaying into the stable lightest neutralino and oneτ-lepton in simplified models where the two staumass eigenstates are degenerate. Stau masses from 120 GeV to 390 GeV are excluded at 95% confidencelevel for a massless lightest neutralino

Search for new phenomena in final states with an energetic jet and large missing transverse momentum in pp collisions at √ s = 8 TeV with the ATLAS detector

Results of a search for new phenomena in final states with an energetic jet and large missing transverse momentum are reported. The search uses 20.3 fb−1 of √ s = 8 TeV data collected in 2012 with the ATLAS detector at the LHC. Events are required to have at least one jet with pT > 120 GeV and no leptons. Nine signal regions are considered with increasing missing transverse momentum requirements between Emiss T > 150 GeV and Emiss T > 700 GeV. Good agreement is observed between the number of events in data and Standard Model expectations. The results are translated into exclusion limits on models with either large extra spatial dimensions, pair production of weakly interacting dark matter candidates, or production of very light gravitinos in a gauge-mediated supersymmetric model. In addition, limits on the production of an invisibly decaying Higgs-like boson leading to similar topologies in the final state are presente

Clinicians’ role in the adoption of an Oncology Decision Support App in Europe and its implications for organizational practices: A Qualitative Case Study

Background: Despite the existence of adequate technological infrastructure and clearer policies, there are situations where users, mainly physicians, resist mobile health (mHealth) solutions. This is of particular concern, bearing in mind that several studies, both in developed and developing countries, showed that clinicians’ adoption is the most influential factor in such solutions’ success. Objective: This research focuses on understanding clinicians’ roles in the adoption of an Oncology Decision Support App, the factors impacting this adoption, and its implications for organizational and social practices. Methods: A qualitative case study of a decision support app in Oncology, called ONCOassist. The data were collected through 17 in-depth interviews with clinicians and nurses in the UK, Ireland, France, Italy, Spain and Portugal. Results: This case demonstrates the affordances and constraints of mHealth technology at the workplace, their implications for the organization of work, and clinicians’ role in their constant development and adoption. The research findings confirmed that factors such as app operation and stability, ease of use, usefulness, cost, and portability play a major role in the adoption process; however, other social factors such as endorsement, neutrality of the content, attitude towards technology, existing workload and internal organizational politics are also perceived as key determinants of clinicians’ adoption. Interoperability and cultural views of mobile usage at work are the key workflow disadvantages; while higher efficiency and performance, sharpened practice and location flexibility are the main workflow advantages. Conclusions: Several organizational implications emerged, suggesting the need for some actions such as fostering a work culture that embraces new technologies, and the creation of new digital roles for clinicians both on the hospitals/clinics and on the development sides but also more collaboration between healthcare organizations and Digital Health providers to enable Electronic Medical Record (EMR) integration and solve any interoperability issues. From a theoretical perspective, we also suggest the addition of a fourth step to Leonardi’s (2018) methodological guidance to account for user engagement; embedding the users in the continuous design and development processes ensures the understanding of user-specific affordances that can then be made more obvious to other users and increase the potential of such tools to go beyond their technological features and have a higher impact on workflow and the organizing process