La evaluación del desempeño laboral y su repercusión en los resultados de los procesos integrales y transversales de los trabajadores de la organización Corona S.A.

En la actualidad las empresas utilizan métodos efectivos para la evaluación del desempeño de todos los empleados, basados en el diseño de objetivos que deben ser planteados de acuerdo a las estrategias de la empresa, estos deben ser medibles, calificables y alcanzables, lo que les permite medir el rendimiento y los resultados de los empleados de la organización, para así determinar el comportamiento de cada empleados tanto en el aspecto técnico como en el social, con la finalidad de determinar y establecer las oportunidades de mejora, fortalezas y debilidades frente a los roles y responsabilidades de cada uno de los empleados. Es importante considerar que el proceso evaluativo debe hacerse con un propósito altamente constructivo buscando siempre la mejora tato del desempeño del funcionario como de la labor realizada, esto con el análisis de las desviaciones encontradas con lo establecido en la política de la organización. Esto debe desembocar en el diagnóstico de las falencias que se estén presentando y en el reconocimiento e incentivos para los que cumplen a cabalidad con lo asignado, por lo tanto se debe observar y evaluar de manera permanente el desempeño de cada empleado y los resultados obtenidos, pensando en la posibilidad de incluir acciones de mejora e incremento de la efectividad de las acciones desarrolladas. La empresa Corona tiene una trayectoria empresarial, la cual es reconocida como una de las mejores empresas en el sector, por el desarrollo de talento, la propuesta de nuevas vacantes, y los beneficios corporativos para todos sus empleados, es evidente que todo esto se logra gracias a las estrategias implementadas que incluyen a todo el personal. Dentro de este contexto es importante resaltar el proceso de evaluación que aplica la empresa Corona, por la cual es fundamental para el desarrollo profesional de los empleados, y así mismo encontrar las oportunidades de mejora para aquellos empleados que no cumplan con las expectativas del cargo, esto le permite diseñar un plan de trabajo enfocado en la mejora del desempeño para así lograr alcanzar las metas de la empresa. El área de Gestión humana es la encargada de plantear las estrategias de la compañía, para establecer los objetivos en conjunto con la Gerencia de la empresa, con la finalidad de alinear a todo el personal mediante los métodos de evaluación de desempeño laboral, monitoreando a todo el personal y así lograr alcanzar los objetivos individuales y colectivos. Es fundamental establecer los métodos adecuados para la evaluación de desempeño, ya que de estas dependen los reconocimientos salarios, la promoción de los cargos, y el fortalecimiento de las habilidades del personal para aplicar a futuras posiciones en la empresa. La empresa Corona es reconocida por sus altos estándares Corporativos, que le permiten desarrollar las mejores estrategias para el crecimiento y desarrollo del personal, ejecutando herramientas para evaluar el desempeño laboral de sus empleados, aunque en la actualidad se ha desarrollado diferentes métodos de evaluación, aún no ha sido efectivo, por esto se requiere diseñar una metodología digital, donde se construyan unos objetivos alineados con la estrategia de la empresa basados en la metodología SMART, Específicos, medibles, alcanzables, relevantes y temporales, para así garantizar la efectividad esperada en el proceso, la cual se deben revisar dos veces en el año para medir el cumplimiento del desempeño y la ejecución del trabajo del personal, dependiendo del método de calificación se puede conseguir un excelente resultado de un buen desempeño, que le permita a los empleados proyectar su carrera profesional y acceder a otras posiciones futuras.Currently, companies use effective methods for evaluating the performance of all employees, based on the design of objectives that must be set according to the company's strategies, these must be measurable, qualifying and achievable, which allows them to measure the performance and results of the organization's employees, in order to determine the behavior of each employee in both the technical and social aspects, in order to determine and establish opportunities for improvement, strengths and weaknesses compared to the roles and responsibilities of each employee. It is important to consider that the evaluation process must be done with a highly constructive purpose, always seeking to improve both the performance of the official and the work done, this with the analysis of the deviations found with what is established in the organization's policy. This should lead to the diagnosis of the shortcomings that are occurring and in the recognition and incentives for those who fully comply with what is assigned, therefore the performance of each employee and the results obtained must be permanently observed and evaluated. thinking about the possibility of including actions to improve and increase the effectiveness of the actions developed. The Corona company has a business history, which is recognized as one of the best companies in the sector, due to the development of talent, the proposal of new vacancies, and the corporate benefits for all its employees, it is evident that all this is achieved thanks to the strategies implemented that include all staff. Within this context, it is important to highlight the evaluation process applied by the Corona Company, for which it is essential for the professional development of employees, and also find opportunities for improvement for those employees who do not meet the expectations of the position. This allows you to design a work plan focused on improving performance in order to achieve the company's goals. The Human Management area is in charge of proposing the company's strategies, to establish the objectives in conjunction with the company's Management, in order to align all the personnel through the methods of evaluation of work performance, monitoring all staff and thus achieve individual and collective goals. It is essential to establish the appropriate methods for performance evaluation, since salary recognition, promotion of positions, and the strengthening of staff skills to apply to future positions in the company depend on these. The Corona company is recognized for its high Corporate standards, which allow it to develop the best strategies for the growth and development of personnel, executing tools to evaluate the work performance of its employees, although different evaluation methods have been developed, even has not been effective, for this reason it is necessary to design a digital methodology, where objectives are built in line with the company's strategy based on the SMART methodology, Specific, measurable, achievable, relevant and temporary, in order to guarantee the expected effectiveness in the process, which must be reviewed twice a year to measure compliance with the performance and execution of the work of the staff, depending on the qualification method, an excellent result of good performance can be achieved, which allows employees to project their professional career and access other future positions

An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge

There is tremendous potential for genome sequencing to improve clinical diagnosis and care once it becomes routinely accessible, but this will require formalizing research methods into clinical best practices in the areas of sequence data generation, analysis, interpretation and reporting. The CLARITY Challenge was designed to spur convergence in methods for diagnosing genetic disease starting from clinical case history and genome sequencing data. DNA samples were obtained from three families with heritable genetic disorders and genomic sequence data were donated by sequencing platform vendors. The challenge was to analyze and interpret these data with the goals of identifying disease-causing variants and reporting the findings in a clinically useful format. Participating contestant groups were solicited broadly, and an independent panel of judges evaluated their performance. RESULTS: A total of 30 international groups were engaged. The entries reveal a general convergence of practices on most elements of the analysis and interpretation process. However, even given this commonality of approach, only two groups identified the consensus candidate variants in all disease cases, demonstrating a need for consistent fine-tuning of the generally accepted methods. There was greater diversity of the final clinical report content and in the patient consenting process, demonstrating that these areas require additional exploration and standardization. CONCLUSIONS: The CLARITY Challenge provides a comprehensive assessment of current practices for using genome sequencing to diagnose and report genetic diseases. There is remarkable convergence in bioinformatic techniques, but medical interpretation and reporting are areas that require further development by many groups

Geographical and temporal distribution of SARS-CoV-2 clades in the WHO European Region, January to June 2020

We show the distribution of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) genetic clades over time and between countries and outline potential genomic surveillance objectives. We applied three genomic nomenclature systems to all sequence data from the World Health Organization European Region available until 10 July 2020. We highlight the importance of real-time sequencing and data dissemination in a pandemic situation, compare the nomenclatures and lay a foundation for future European genomic surveillance of SARS-CoV-2

Optimasi Portofolio Resiko Menggunakan Model Markowitz MVO Dikaitkan dengan Keterbatasan Manusia dalam Memprediksi Masa Depan dalam Perspektif Al-Qur`an

Risk portfolio on modern finance has become increasingly technical, requiring the use of sophisticated mathematical tools in both research and practice. Since companies cannot insure themselves completely against risk, as human incompetence in predicting the future precisely that written in Al-Quran surah Luqman verse 34, they have to manage it to yield an optimal portfolio. The objective here is to minimize the variance among all portfolios, or alternatively, to maximize expected return among all portfolios that has at least a certain expected return. Furthermore, this study focuses on optimizing risk portfolio so called Markowitz MVO (Mean-Variance Optimization). Some theoretical frameworks for analysis are arithmetic mean, geometric mean, variance, covariance, linear programming, and quadratic programming. Moreover, finding a minimum variance portfolio produces a convex quadratic programming, that is minimizing the objective function ðð¥with constraintsð ð 𥠥 ðandð´ð¥ = ð. The outcome of this research is the solution of optimal risk portofolio in some investments that could be finished smoothly using MATLAB R2007b software together with its graphic analysis

Photography-based taxonomy is inadequate, unnecessary, and potentially harmful for biological sciences

The question whether taxonomic descriptions naming new animal species without type specimen(s) deposited in collections should be accepted for publication by scientific journals and allowed by the Code has already been discussed in Zootaxa (Dubois & Nemésio 2007; Donegan 2008, 2009; Nemésio 2009a–b; Dubois 2009; Gentile & Snell 2009; Minelli 2009; Cianferoni & Bartolozzi 2016; Amorim et al. 2016). This question was again raised in a letter supported by 35 signatories published in the journal Nature (Pape et al. 2016) on 15 September 2016. On 25 September 2016, the following rebuttal (strictly limited to 300 words as per the editorial rules of Nature) was submitted to Nature, which on 18 October 2016 refused to publish it. As we think this problem is a very important one for zoological taxonomy, this text is published here exactly as submitted to Nature, followed by the list of the 493 taxonomists and collection-based researchers who signed it in the short time span from 20 September to 6 October 2016

Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer.

Genome-wide association studies (GWAS) and large-scale replication studies have identified common variants in 79 loci associated with breast cancer, explaining ∼14% of the familial risk of the disease. To identify new susceptibility loci, we performed a meta-analysis of 11 GWAS, comprising 15,748 breast cancer cases and 18,084 controls together with 46,785 cases and 42,892 controls from 41 studies genotyped on a 211,155-marker custom array (iCOGS). Analyses were restricted to women of European ancestry. We generated genotypes for more than 11 million SNPs by imputation using the 1000 Genomes Project reference panel, and we identified 15 new loci associated with breast cancer at P < 5 × 10(-8). Combining association analysis with ChIP-seq chromatin binding data in mammary cell lines and ChIA-PET chromatin interaction data from ENCODE, we identified likely target genes in two regions: SETBP1 at 18q12.3 and RNF115 and PDZK1 at 1q21.1. One association appears to be driven by an amino acid substitution encoded in EXO1.BCAC is funded by Cancer Research UK (C1287/A10118, C1287/A12014) and by the European Community's Seventh Framework Programme under grant agreement 223175 (HEALTH-F2-2009-223175) (COGS). Meetings of the BCAC have been funded by the European Union COST programme (BM0606). Genotyping on the iCOGS array was funded by the European Union (HEALTH-F2-2009-223175), Cancer Research UK (C1287/A10710, C8197/A16565), the Canadian Institutes of Health Research (CIHR) for the CIHR Team in Familial Risks of Breast Cancer program and the Ministry of Economic Development, Innovation and Export Trade of Quebec, grant PSR-SIIRI-701. Combination of the GWAS data was supported in part by the US National Institutes of Health (NIH) Cancer Post-Cancer GWAS initiative, grant 1 U19 CA148065-01 (DRIVE, part of the GAME-ON initiative). For a full description of funding and acknowledgments, see the Supplementary Note.This is the author accepted manuscript. The final version is available from NPG via http://dx.doi.org/10.1038/ng.324

Measurement of b jet shapes in proton-proton collisions at root s=5.02 TeV

We present the first study of charged-hadron production associated with jets originating from b quarks in proton-proton collisions at a center-of-mass energy of 5.02 TeV. The data sample used in this study was collected with the CMS detector at the CERN LHC and corresponds to an integrated luminosity of 27.4 pb(-1). To characterize the jet substructure, the differential jet shapes, defined as the normalized transverse momentum distribution of charged hadrons as a function of angular distance from the jet axis, are measured for b jets. In addition to the jet shapes, the per-jet yields of charged particles associated with b jets are also quantified, again as a function of the angular distance with respect to the jet axis. Extracted jet shape and particle yield distributions for b jets are compared with results for inclusive jets, as well as with the predictions from the pythia and herwig++ event generators.Peer reviewe

Search for Physics beyond the Standard Model in Events with Overlapping Photons and Jets

Results are reported from a search for new particles that decay into a photon and two gluons, in events with jets. Novel jet substructure techniques are developed that allow photons to be identified in an environment densely populated with hadrons. The analyzed proton-proton collision data were collected by the CMS experiment at the LHC, in 2016 at root s = 13 TeV, and correspond to an integrated luminosity of 35.9 fb(-1). The spectra of total transverse hadronic energy of candidate events are examined for deviations from the standard model predictions. No statistically significant excess is observed over the expected background. The first cross section limits on new physics processes resulting in such events are set. The results are interpreted as upper limits on the rate of gluino pair production, utilizing a simplified stealth supersymmetry model. The excluded gluino masses extend up to 1.7 TeV, for a neutralino mass of 200 GeV and exceed previous mass constraints set by analyses targeting events with isolated photons.Peer reviewe

Measurement of the azimuthal anisotropy of Y(1S) and Y(2S) mesons in PbPb collisions at root s(NN)=5.02 TeV

The second-order Fourier coefficients (v(2)) characterizing the azimuthal distributions of Y(1S) and Y(2S) mesons produced in PbPb collisions at root s(NN) = 5.02 TeV are studied. The Y mesons are reconstructed in their dimuon decay channel, as measured by the CMS detector. The collected data set corresponds to an integrated luminosity of 1.7 nb(-1). The scalar product method is used to extract the v2 coefficients of the azimuthal distributions. Results are reported for the rapidity range vertical bar y vertical bar < 2.4, in the transverse momentum interval 0 < pT < 50 GeV/c, and in three centrality ranges of 10-30%, 30-50% and 50-90%. In contrast to the J/psi mesons, the measured v(2) values for the Y mesons are found to be consistent with zero. (C) 2021 The Author(s). Published by Elsevier B.V.Peer reviewe

Measurement of the top quark forward-backward production asymmetry and the anomalous chromoelectric and chromomagnetic moments in pp collisions at √s = 13 TeV

Abstract The parton-level top quark (t) forward-backward asymmetry and the anomalous chromoelectric (d̂ t) and chromomagnetic (μ̂ t) moments have been measured using LHC pp collisions at a center-of-mass energy of 13 TeV, collected in the CMS detector in a data sample corresponding to an integrated luminosity of 35.9 fb−1. The linearized variable AFB(1) is used to approximate the asymmetry. Candidate t t ¯ events decaying to a muon or electron and jets in final states with low and high Lorentz boosts are selected and reconstructed using a fit of the kinematic distributions of the decay products to those expected for t t ¯ final states. The values found for the parameters are AFB(1)=0.048−0.087+0.095(stat)−0.029+0.020(syst),μ̂t=−0.024−0.009+0.013(stat)−0.011+0.016(syst), and a limit is placed on the magnitude of | d̂ t| &lt; 0.03 at 95% confidence level. [Figure not available: see fulltext.