202 research outputs found
Chiral dynamics of p-wave in K^- p and coupled states
We perform an evaluation of the p-wave amplitudes of meson-baryon scattering
in the strangeness S=-1 sector starting from the lowest order chiral
Lagrangians and introducing explicitly the Sigma^* field with couplings to the
meson-baryon states obtained using SU(6) symmetry. The N/D method of
unitarization is used, equivalent, in practice, to the use of the
Bethe-Salpeter equation with a cut-off. The procedure leaves no freedom for the
p-waves once the s-waves are fixed and thus one obtains genuine predictions for
the p-wave scattering amplitudes, which are in good agreement with experimental
results for differential cross sections, as well as for the width and partial
decay widths of the Sigma^*(1385).Comment: LaTeX, 18 pages, 6 figure
Determining design requirements for active aging: Personas, experience maps, and stakeholders
Microbe sampling by mucosal dendritic cells is a discrete, MyD88-independent stepin ΔinvG S. Typhimurium colitis
Intestinal dendritic cells (DCs) are believed to sample and present commensal bacteria to the gut-associated immune system to maintain immune homeostasis. How antigen sampling pathways handle intestinal pathogens remains elusive. We present a murine colitogenic Salmonella infection model that is highly dependent on DCs. Conditional DC depletion experiments revealed that intestinal virulence of S. Typhimurium SL1344 ΔinvG mutant lacking a functional type 3 secretion system-1 (ΔinvG)critically required DCs for invasion across the epithelium. The DC-dependency was limited to the early phase of infection when bacteria colocalized with CD11c+CX3CR1+ mucosal DCs. At later stages, the bacteria became associated with other (CD11c−CX3CR1−) lamina propria cells, DC depletion no longer attenuated the pathology, and a MyD88-dependent mucosal inflammation was initiated. Using bone marrow chimeric mice, we showed that the MyD88 signaling within hematopoietic cells, which are distinct from DCs, was required and sufficient for induction of the colitis. Moreover, MyD88-deficient DCs supported transepithelial uptake of the bacteria and the induction of MyD88-dependent colitis. These results establish that pathogen sampling by DCs is a discrete, and MyD88-independent, step during the initiation of a mucosal innate immune response to bacterial infection in vivo
Development of a GEM-TPC prototype
The use of GEM foils for the amplification stage of a TPC instead of a con-
ventional MWPC allows one to bypass the necessity of gating, as the backdrift
is suppressed thanks to the asymmetric field configuration. This way, a novel
continuously running TPC, which represents one option for the PANDA central
tracker, can be realized. A medium sized prototype with a diameter of 300 mm
and a length of 600 mm will be tested inside the FOPI spectrometer at GSI using
a carbon or lithium beam at intermediate energies (E = 1-3AGeV). This detector
test under realistic experimental conditions should allow us to verify the
spatial resolution for single tracks and the reconstruction capability for
displaced vertexes. A series of physics measurement implying pion beams is
scheduled with the FOPI spectrometer together with the GEM-TPC as well.Comment: 5 pages, 4 figures, Proceedings for 11th ICATTP conference in como
(italy
Testing foundations of quantum mechanics with photons
The foundational ideas of quantum mechanics continue to give rise to
counterintuitive theories and physical effects that are in conflict with a
classical description of Nature. Experiments with light at the single photon
level have historically been at the forefront of tests of fundamental quantum
theory and new developments in photonics engineering continue to enable new
experiments. Here we review recent photonic experiments to test two
foundational themes in quantum mechanics: wave-particle duality, central to
recent complementarity and delayed-choice experiments; and Bell nonlocality
where recent theoretical and technological advances have allowed all
controversial loopholes to be separately addressed in different photonics
experiments.Comment: 10 pages, 5 figures, published as a Nature Physics Insight review
articl
Atmospheric aerosol characterization with the Dutch–Chinese FAST formation flying mission
Rapid Transition towards the Division of Labor via Evolution of Developmental Plasticity
A crucial step in several major evolutionary transitions is the division of labor between components of the emerging higher-level evolutionary unit. Examples include the separation of germ and soma in simple multicellular organisms, appearance of multiple cell types and organs in more complex organisms, and emergence of casts in eusocial insects. How the division of labor was achieved in the face of selfishness of lower-level units is controversial. I present a simple mathematical model describing the evolutionary emergence of the division of labor via developmental plasticity starting with a colony of undifferentiated cells and ending with completely differentiated multicellular organisms. I explore how the plausibility and the dynamics of the division of labor depend on its fitness advantage, mutation rate, costs of developmental plasticity, and the colony size. The model shows that the transition to differentiated multicellularity, which has happened many times in the history of life, can be achieved relatively easily. My approach is expandable in a number of directions including the emergence of multiple cell types, complex organs, or casts of eusocial insects
Varieties of living things: Life at the intersection of lineage and metabolism
publication-status: Publishedtypes: Articl
Glueballs, Hybrids, Multiquarks. Experimental facts versus QCD inspired concepts
The spectroscopy of light and heavy mesons is reviewed with emphasis on
glueballs, hybrids, and tetraquarks.Comment: 266 pages, 117 figures, 39 tables. to be published in Physics Report
Entangled lives: Implications of the developmental origins of health and disease hypothesis for bioarchaeology and the life course
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