706 research outputs found

    Preliminary Limits on the WIMP-Nucleon Cross Section from the Cryogenic Dark Matter Search (CDMS)

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    We are conducting an experiment to search for WIMPs, or weakly-interacting massive particles, in the galactic halo using terrestrial detectors. This generic class of hypothetical particles, whose properties are similar to those predicted by extensions of the standard model of particle physics, could comprise the cold component of non-baryonic dark matter. We describe our experiment, which is based on cooled germanium and silicon detectors in a shielded low-background cryostat. The detectors achieve a high degree of background rejection through the simultaneous measurement of the energy in phonons and ionization. Using exposures on the order of one kilogram-day from initial runs of our experiment, we have achieved (preliminary) upper limits on the WIMP-nucleon cross section that are comparable to much longer runs of other experiments.Comment: 5 LaTex pages, 5 eps figs, epsf.sty, espcrc2dsa2.sty. Proceedings of TAUP97, Gran Sasso, Italy, 7-11 Sep 1997, Nucl. Phys. Suppl., A. Bottino, A. di Credico and P. Monacelli (eds.). See also http://cfpa.berkeley.ed

    Isovalent doping and the CiOi defect in germanium

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    Oxygen–carbon defects have been studied for decades in silicon but are less well established in germanium. In the present study we employ density functional theory calculations to study the structure of the CiOi defect in germanium. Additionally, we investigate the interaction the CiOi defect with isovalent dopants such as silicon and tin. It is calculated that the CiOi defects will preferentially form near isovalent dopants in germanium. Interestingly the structure of the dopant-CiOi defects is different with the Sn residing next to the Oi whereas the Si atom bonds with the Ci. The differences in the structure of CiOi defects in the vicinity of isovalent dopants are discussed

    Interaction of microtubules and actin during the post-fusion phase of exocytosis

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    Exocytosis is the intracellular trafficking step where a secretory vesicle fuses with the plasma membrane to release vesicle content. Actin and microtubules both play a role in exocytosis; however, their interplay is not understood. Here we study the interaction of actin and microtubules during exocytosis in lung alveolar type II (ATII) cells that secrete surfactant from large secretory vesicles. Surfactant extrusion is facilitated by an actin coat that forms on the vesicle shortly after fusion pore opening. Actin coat compression allows hydrophobic surfactant to be released from the vesicle. We show that microtubules are localized close to actin coats and stay close to the coats during their compression. Inhibition of microtubule polymerization by colchicine and nocodazole affected the kinetics of actin coat formation and the extent of actin polymerisation on fused vesicles. In addition, microtubule and actin cross-linking protein IQGAP1 localized to fused secretory vesicles and IQGAP1 silencing influenced actin polymerisation after vesicle fusion. This study demonstrates that microtubules can influence actin coat formation and actin polymerization on secretory vesicles during exocytosis

    Study of hadronic event-shape variables in multijet final states in pp collisions at √s=7 TeV

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    Search for light bosons in decays of the 125 GeV Higgs boson in proton-proton collisions at root s=8 TeV

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    Search for new physics in the multijet and missing transverse momentum final state in proton-proton collisions at √s=8 Tev

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    Measurement of Higgs boson production and properties in the WW decay channel with leptonic final states

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    Development of 100^{100}Mo-containing scintillating bolometers for a high-sensitivity neutrinoless double-beta decay search

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    We report recent achievements in the development of scintillating bolometers to search for neutrinoless double-beta decay of 100^{100}Mo. The presented results have been obtained in the framework of the LUMINEU, LUCIFER and EDELWEISS collaborations, and are now part of the R\&D activities towards CUPID (CUORE Update with Particle IDentification), a proposed next-generation double-beta decay experiment based on the CUORE experience. We have developed a technology for the production of large mass (\sim1 kg), high optical quality, radiopure zinc and lithium molybdate crystal scintillators (ZnMoO4_4 and Li2_2MoO4_4, respectively) from deeply purified natural and 100^{100}Mo-enriched molybdenum. The procedure is applied for a routine production of enriched crystals. Furthermore, the technology of a single detector module consisting of a large-volume (100\sim 100~cm3^3) Zn100^{100}MoO4_4 and Li2_2100^{100}MoO4_4 scintillating bolometer has been established, demonstrating performance and radiopurity that are close to satisfy the demands of CUPID. In particular, the FWHM energy resolution of the detectors at 2615 keV --- near the QQ-value of the double-beta transition of 100^{100}Mo (3034~keV) --- is \approx 4--10~keV. The achieved rejection of α\alpha-induced dominant background above 2.6~MeV is at the level of more than 99.9\%. The bulk activity of 232^{232}Th (228^{228}Th) and 226^{226}Ra in the crystals is below 10 μ\muBq/kg. Both crystallization and detector technologies favor Li2_2MoO4_4, which was selected as a main element for the realization of a CUPID demonstrator (CUPID-0/Mo) with \sim7 kg of 100^{100}Mo

    Constraints on parton distribution functions and extraction of the strong coupling constant from the inclusive jet cross section in pp collisions at √s=7 TeV

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