27 research outputs found
Chiapas : entre el autoritarismo y la transiciĂłn democrĂĄtica, desde Acteal hasta el diĂĄlogo EZLN y sociedad civil
- Author
- Blanco-Cordero Carlos A.
- Casillas-EnrĂquez JosĂ© F.
- Cisneros-Mendoza Mario A.
- Corona-Cadena Rubén I.
- Estrada-JĂĄcquez Guillermo
- GonzĂĄlez-CandĂa Jorge A.
- Gutiérrez-Bautista Omar D.
- Lozano-DelosSantos Samuel
- Mendoza-ZĂĄrate Gabriel
- Moro-Madrid Luis G.
- Rivadeneyra-Fentanes Rafael
- Roberto-LĂłpez Facundo
- SantillĂĄn-HernĂĄndez Antonio
- Torres-Arredondo Salvador E.
- Velasco-Yåñez David
- Publication venue
- 'ITESO, A.C.'
- Publication date
- 01/11/1998
- Field of study
Obra cuya intenciĂłn es dar cuenta de los diversos actores sociales involucrados en el conflicto de Chiapas, a nivel polĂtico, econĂłmico y sociocultural. El texto recupera un taller de anĂĄlisis de coyuntura sobre el tema, realizado en agosto de 1998.ITESO, A.C
Occupational Toluene Exposure Induces Cytochrome P450 2E1 mRNA Expression in Peripheral Lymphocytes
- Author
- Publication venue
- National Institute of Environmental Health Sciences
- Publication date
- 13/10/2005
- Field of study
Print workers are exposed to organic solvents, of which the systemic toxicant toluene is a main component. Toluene induces expression of cytochrome P450 2E1 (CYP2E1), an enzyme involved in its own metabolism and that of other protoxicants, including some procarcinogens. Therefore, we investigated the association between toluene exposure and the CYP2E1 response, as assessed by mRNA content in peripheral lymphocytes or the 6-hydroxychlorzoxazone (6OH-CHZ)/chlorzoxazone (CHZ) quotient (known as CHZ metabolic ratio) in plasma, and the role of genotype (5âČ-flanking region RsaI/PstI polymorphic sites) in 97 male print workers. The geometric mean (GM) of toluene concentration in the air was 52.80 ppm (10â760 ppm); 54% of the study participants were exposed to toluene concentrations that exceeded the maximum permissible exposure level (MPEL). The GM of urinary hippuric acid at the end of a work shift (0.041 g/g creatinine) was elevated relative to that before the shift (0.027 g/g creatinine; p < 0.05). The GM of the CHZ metabolic ratio was 0.33 (0â9.3), with 40% of the subjects having ratios below the GM. However, the average CYP2E1 mRNA level in peripheral lymphocytes was 1.07 (0.30â3.08), and CYP2E1 mRNA levels within subjects correlated with the toluene exposure ratio (environmental toluene concentration:urinary hippuric acid concentration) (p = 0.014). Genotype did not alter the association between the toluene exposure ratio and mRNA content. In summary, with further validation, CYP2E1 mRNA content in peripheral lymphocytes could be a sensitive and noninvasive biomarker for the continuous monitoring of toluene effects in exposed persons
Treatment with tocilizumab or corticosteroids for COVID-19 patients with hyperinflammatory state: a multicentre cohort study (SAM-COVID-19)
- Author
- Abora Rial-Villavecchia
- Adriana SĂĄnchez Serrano
- AdriĂĄn Sousa
- Aina Gomila Grange
- Ainhoa Sanjuan LĂłpez
- Ainhoa Urrutia Losada
- Alberto Gato DĂez
- Alberto Romero-Palacios
- Alberto Serrano MartĂnez
- Alejandra Duarte Borges
- Alejandro Araujo
- Alexander Rombauts
- Alexandra de la Vega
- Alexandre PĂ©rez GonzĂĄlez
- Alfonso Cabello Ăbeda
- Alfonso Lluna Carrascosa
- Alicia HernĂĄndez Torres
- Almudena HernĂĄndez Milian
- Ana Alberich Conesa
- Ana Correa Ruiz
- Ana Escoresca
- Ana Ferrer Ribera
- Ana Isabel Mariño Callejo
- Ana Isabel PelĂĄez Ballesta
- Ana Such Diaz
- Andrea MartĂn Plata
- André Barbosa Ventura
- Andrés Ruiz Sancho
- Ane Andrés Eisenhofer
- Anonymous
- Antonia Alcaraz
- Antonia SepĂșlveda Berrocal
- Antonio José Ruiz Reina
- Antonio Plata Ciezar
- Araceli GonzĂĄlez-Cuevas
- Arantzazu Mera Fidalgo
- Ariadna De Genover Gil
- Aroa Villoslada Gelabert
- Aychel Elena Roura Piloto
- Beatriz Diaz Pollan
- Beatriz Dietl
- Beatriz PĂ©rez-Monte MĂnguez
- Beatriz Sobrino Diaz
- Beigel
- BelĂ©n Loeches YagĂŒe
- Berenguer
- Bhimraj
- Blanca Alonso MartĂnez
- Blanca MartĂnez Cifre
- Blanca Pinilla
- Borja Gracia-Tello
- Campochiaro
- Capra
- Carlos Bea Serrano
- Carlos Dueñas Gutiérrez
- Carlos Enrique Sabbagh Fajardo
- Carlota Gudiol
- Carmen Aguayo Jiménez
- Carmen Herrero RodrĂguez
- Carmen Infante
- Carmen Yllera
- Carolina RoldĂĄn Fontana
- Channappanavar
- Chen
- Chen
- Chiara Fanciulli
- Clara MartĂnez Montes
- Clara Muñoz Aguirre
- Claudia GonzĂĄlez Rico
- Claudia Ălvarez-Pouso
- Claudio Bueno
- ConcepciĂłn GarcĂa-GarcĂa
- ConcepciĂłn Gonzalo
- Cristina BadĂa
- Cristina Cervera Acedo
- Cristina DĂez
- Cristina Lojo Cruz
- Cristina PelĂĄez Ballesta
- Cristina PĂ©rez GarcĂa
- Daniel Molina Morant
- Daniel Podzamczer
- Daniel Roger Zapata
- David Roa Alonso
- David Vinuesa GarcĂa
- Diana Piñar Cabezos
- Efrén Sånchez Vidal
- Elena Aranda Rife
- Elena Bereciartua Bastarrica
- Elena HellĂn-Valiente
- Elena MarĂn
- Elena Morcillo RodrĂguez
- Elena Salamanca-Rivera
- Elena Trigo Esteban
- Elena Ălvaro Alonso
- Eleni Patera
- Elisa Cordero-MatĂa
- Elisa GarcĂa VĂĄzquez
- Elizabet Petkova-Saiz
- EncarnaciĂłn Moral Escudero
- Enrique Bernal Morell
- Enrique MĂguez Rey
- Ester Saez de Adana Arroniz
- Esther Aznar Muñoz
- Esther Calbo
- Esther MartĂnez Birlanga
- Eva Jiménez Gonzålez de Buitrago
- Eva León Jiménez
- Eva Pilar GarcĂa Villalba
- Eva Talavera GarcĂa
- Evangelia Anna MarĂa Zioga
- Fadel
- Fernando de la Calle Prieto
- Fernando FernĂĄndez SĂĄnchez
- Francesc Escrihuela
- Francesca Gioia
- Francisco Anguita Santos
- Francisco Arnaiz de las Revillas
- Francisco Javier De la Hera FernĂĄndez
- Francisco Javier MartĂnez Marcos
- Francisco Javier RodrĂguez GĂłmez
- Francisco Muñoz Beamud
- Francisco Tejerina
- Fåtima Brañas Baztån
- Gabriela Abelenda-Alonso
- Gabriela Escudero LĂłpez
- Galadriel Pellejero
- Gaspar Duro Ruiz
- Gemma Mut Ramon
- Gemma Muñiz Nicolås
- Guan
- Guaraldi
- Guillem Policarpo Torres
- Guillermo Cuevas Tascon
- Gurutz Orbe NarvĂĄez
- GĂłmez LucĂa
- Harris
- Helem HaydeĂ© VĂlchez Rueda
- Helena AlbendĂn Iglesias
- HoffmannâLa Roche
- Horby
- Hortensia Ălvarez DĂaz
- Ignacio Pina
- Ignacio PĂ©rez Valero
- Ignacio Ălvarez RodrĂguez
- Inmaculada GonzĂĄlez-Cuello
- Inmaculada JarrĂn
- Inmaculada LĂłpez-Montesinos
- Inés Fernåndez Jiménez
- Inés Pérez Zapata
- Irene MartĂn Rubio
- Isabel A. PĂ©rez HernĂĄndez
- Isabel Asschert AgĂŒero
- Isabel Gutiérrez
- Isabel GutiĂ©rrez MartĂn
- Isabel RĂĄbago Lorite
- Isidoro FernĂĄndez Romero
- Israel Sevilla Moreno
- Itziar Arrieta-Aldea
- IvĂĄn PelegrĂn Senent
- Ivån Piñero
- Jara Llenas-GarcĂa
- Javier De la Torre Lima
- Javier Garrido
- Javier Martin Guerra
- JerĂłnimo PachĂłn
- Jessica Souto Higueras
- JesĂșs FortĂșn Abete
- JesĂșs RodrĂguez-Baño
- JesĂșs Ruiz AragĂłn
- Joan GĂłmez-Junyent
- Joel ElĂas Chara Cervantes
- Jon Ugalde Espiñeira
- Jordi CarratalĂ
- Jordi NiubĂł
- Jorge CalderĂłn Parra
- Jorge Calvo
- Jorge Parra Ruiz
- Jorge Valencia de la Rosa
- Josefina GarcĂa GarcĂa
- Josune Goikoetxea Agirre
- José A. Oteo Revuelta
- José Antonio Iribarren Loyarte
- José Javier Castrodeza Sanz
- José Joaquin Portu Zapirain
- José Luis Sierra-Monzón
- José M. Azcona Gutiérrez
- JosĂ© M. GarcĂa de Lomas Guerrero
- José Manuel Tafalla Torres
- JosĂ© MarĂa Reguera Iglesias
- JosĂ© MarĂa Robaina BordĂłn
- José Miguel Cisneros
- José Ramón Arribas
- Juan Berenguer
- Juan Berenguer
- Juan Carlos Gainzarain Arana
- Juan Carlos LĂłpez
- Juan Carlos Ramos Ramos
- Juan Diego Ruiz Mesa
- Juan GonzĂĄlez GarcĂa
- Juan GonzĂĄlez-Moreno
- Juan Mora Delgado
- Juan Pablo Avilés Parra
- Juan RamĂłn DomĂnguez Vicent
- Juan Salillas Hernando
- Juan Torres Macho
- Judit Villar-GarcĂa
- Julen Cadiñaños Loidi
- Julio GarcĂa RodrĂguez
- Justo Lajusticia Aisa
- JĂșlia Pareja Coca
- Karim Mohamed RamĂrez
- Laia Lorenzo-Esteller
- Laia Raich Montiu
- Laura Castelo Corral
- Laura GarcĂa Escudero
- Laura GarcĂa Pereña
- Laura Guio CarriĂłn
- Laura Parra GĂłmez
- Laura RodrĂguez FernĂĄndez
- Le
- Leire PĂ©rez-Latorre
- Lluis Planas Bibiloni
- Lorea Arteche Eguizabal
- Lourdes Bladé Vidal
- Lucia Boix Palop
- Lucia SuĂĄrez
- Lucia Valiente de Santis
- LucĂa Ramos Merino
- Luisa GonzĂĄlez-Iglesias
- Luz MartĂn Carbonero
- Ma del Carmen Liébana Martos
- Ma JesĂșs del Amor EspĂn
- Ma Luisa FernĂĄndez Ăvila
- Ma Teresa PĂ©rez RodrĂguez
- Maialen Ibarguren Pinilla
- Manuel Alejandro GĂĄlvez Bobadilla
- Manuela Aguilar-Guisado
- Margarita RamĂrez
- Mario Pérez Butragueño
- Mariona Tasias Pitarch
- Marta Arsuaga Vicente
- Marta AsĂn-Corrochano
- Marta DĂaz MenĂ©ndez
- Marta FernĂĄndez Morales
- Marta Ibarrola Hierro
- Marta Jiménez Escrig
- Marta Lamata Subero
- Marta Navarro VilasarĂł
- Marta Santos Peña
- MartĂn Guillermo
- MarĂa Antonia Ribot Sanso
- MarĂa Carmen Fariñas Ălvarez
- MarĂa D. del Toro
- MarĂa Erostarbe Gallardo
- MarĂa HernĂĄndez-Bonaga
- MarĂa Isabel Guirado Torrecillas
- MarĂa JesĂșs Bustinduy Odriozola
- MarĂa JosĂ© RĂos-Villegas
- MarĂa Lorena MarĂa Valle Feijoo Begoña RodrĂguez Ferreira
- MarĂa Luisa Machado Sicilia
- MarĂa Paz GarcĂa Butenegro
- MarĂa Pilar Toledano Sierra
- MarĂa Rivas-Carmenado
- MarĂa RodrĂguez Mayo
- MarĂa RuĂz Campuzano
- MarĂa Soledad GarcĂa de Carlos
- MarĂa Victoria FernĂĄndez-Baca
- MarĂa Yllescas
- MarĂa Ăngeles Garcinuño
- Mehta
- Melchor Riera Jaume
- Mercedes Clemente Presas
- Meritxell Gavalda Manso
- Meritxell Ortega Montoliu
- Miguel GĂłrgolas HernĂĄndez-Mora
- Miguel Pedromingo Kus
- Miguel Salvert LletĂ
- Miguel Torralba GonzĂĄlez de Suso
- Miguel Ăngel MorĂĄn RodrĂguez
- Mikel Temprano Gogenola
- Miquel Hortos Alsina
- Miquel Pujol
- Mohamed Kallouchi
- Montserrat Sanmarti Vilamala
- Montserrat Viqueira GonzĂĄlez
- MĂČnica Angerri Nadal
- Mónica Liébana Gómez
- Nerea Carrasco AntĂłn
- NicolĂĄs JimĂ©nez-GarcĂa
- Nicolås Merchante Gutiérrez
- Nieves de la Cruz Felipe
- Nieves Valcarce Pardeiro
- Olga Meca Birlanga
- Olga SĂĄnchez-Pernaute
- Onofre MartĂnez Madrid
- Oscar Sanz PelĂĄez
- Pablo Ryan
- Paloma Albiol Viñals
- Patricia Gonzålez Muñiz
- Patricia GonzĂĄlez-Ruano PĂ©rez
- Patricia Jiménez Aguilar
- Patricia MartĂnez MartĂn
- Paula Mendoza Roy
- Paula Santibañez Såenz
- Pedro Gil Divasson
- Pedro MartĂnez PĂ©rez-Crespo
- Pedro Ăngel Cuadros Tito
- Pere Comas Casanova
- Pilar MartĂn DĂĄvila
- Pilar Vizcarra
- Rafae Silvariño Fernåndez
- Raquel Ălvarez Franco
- Rebeca Longueira
- Regino RodrĂguez Ălvarez
- Reinaldo EspĂndola GĂłmez
- Ricardo Gil SĂĄnchez
- Rita Godoy Lorenzo
- RocĂo Montejano SĂĄnchez
- Rojas-Marte
- Rosa de Miguel Buckley
- Rosa Oltra Sempere
- Rosana Rouco Esteves Marques
- Rosario Castilla Ortiz
- Sabela SĂĄnchez Trigo
- Saioa Domingo Echaburu
- Salvador PĂ©rez-Galera
- Santiago Moreno Guillén
- Santiago PĂ©rez Parra
- Sara Lidia Kamel Rey
- Sara Vela Bernal
- Sara Velasco Fuentes
- Sergio España Cueto
- Sergio Gilaberte ReyzĂĄbal
- Sergio Manuel Santana BĂĄez
- Sergio PĂ©rez Pinto
- Sergio RomĂĄn Soto
- Silvana Fiorante
- Silvia GarcĂa MartĂnez
- Silvia SuĂĄrez
- Sonia Calzado Isbert
- Sonia GarcĂa Prieto
- Sonsoles Salto
- Tamara CaĂnzos Romero
- Teresa AldabĂł
- Teresa AldĂĄmiz-EchevarrĂa
- Teresa Giménez
- Vanesa Alende Castro
- Vicens DĂaz de Brito FernĂĄndez
- Vicente de la Rosa
- Violeta Ramos Sesma
- Virginia Almadana
- Virginia FernĂĄndez Espinilla
- Virginia Isern FernĂĄndez
- Virginia Naranjo Velasco
- VĂctor Asensi
- Xabier Kortajarena Urkola
- Xavier Sanz Salvador
- Ye
- Yolanda Meije Castillo
- Yuan
- Zaira R. Palacios Baena
- Zhang
- Zuriñe Ortiz de Zårate Ibarra
- Ăngel DomĂnguez-Castellano
- Ăngeles GarcĂa Flores
- Ăngeles Muñoz
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/08/2020
- Field of study
Objectives: The objective of this study was to estimate the association between tocilizumab or corticosteroids and the risk of intubation or death in patients with coronavirus disease 19 (COVID-19) with a hyperinflammatory state according to clinical and laboratory parameters.
Methods: A cohort study was performed in 60 Spanish hospitals including 778 patients with COVID-19 and clinical and laboratory data indicative of a hyperinflammatory state. Treatment was mainly with tocilizumab, an intermediate-high dose of corticosteroids (IHDC), a pulse dose of corticosteroids (PDC), combination therapy, or no treatment. Primary outcome was intubation or death; follow-up was 21 days. Propensity score-adjusted estimations using Cox regression (logistic regression if needed) were calculated. Propensity scores were used as confounders, matching variables and for the inverse probability of treatment weights (IPTWs).
Results: In all, 88, 117, 78 and 151 patients treated with tocilizumab, IHDC, PDC, and combination therapy, respectively, were compared with 344 untreated patients. The primary endpoint occurred in 10 (11.4%), 27 (23.1%), 12 (15.4%), 40 (25.6%) and 69 (21.1%), respectively. The IPTW-based hazard ratios (odds ratio for combination therapy) for the primary endpoint were 0.32 (95%CI 0.22-0.47; p < 0.001) for tocilizumab, 0.82 (0.71-1.30; p 0.82) for IHDC, 0.61 (0.43-0.86; p 0.006) for PDC, and 1.17 (0.86-1.58; p 0.30) for combination therapy. Other applications of the propensity score provided similar results, but were not significant for PDC. Tocilizumab was also associated with lower hazard of death alone in IPTW analysis (0.07; 0.02-0.17; p < 0.001).
Conclusions: Tocilizumab might be useful in COVID-19 patients with a hyperinflammatory state and should be prioritized for randomized trials in this situatio
Global variations in diabetes mellitus based on fasting glucose and haemogloblin A1c
- Author
- Abbasi-Kangevari Mohsen
- Abdul Rahim Hanan F.
- Abu-Rmeileh Niveen M.
- Adambekov Shalkar
- Adams Robert J.
- Aekplakorn Wichai
- Agdeppa Imelda A.
- Aghazadeh-Attari Javad
- Aguilar-Salinas Carlos A.
- Agyemang Charles
- Ahmad Noor Ani
- Ahmadi Ali
- Ahmadi Naser
- Ahmadi Nastaran
- Ahmed Soheir H.
- Ajlouni Kamel
- Al Asfoor Deena
- Al Qaoud Nawal M.
- Al-Hina Halima
- Al-Lahou Badreya
- Al-Lawati Jawad A.
- Alarouj Monira
- AlBuhairan Fadia
- AlDhukair Shahla
- Aldwairji Maryam A.
- Ali Mohamed M.
- Alinezhad Farbod
- Alkandari Abdullah
- Alomirah Husam F.
- Aly Eman
- Amarapurkar Deepak N.
- Andersen Lars Bo
- Anderssen Sigmund A.
- Andrade Dolores S.
- Anjana Ranjit Mohan
- Ansari-Moghaddam Alireza
- Aounallah-Skhiri Hajer
- Aris Tahir
- Arlappa Nimmathota
- Aryal Krishna K.
- Assah Felix K.
- Assembekov Batyrbek
- Auvinen Juha
- AvdiÄovĂĄ MĂĄria
- Azad Kishwar
- Azimi-Nezhad Mohsen
- Azizi Fereidoun
- Bacopoulou Flora
- Balakrishna Nagalla
- Bamoshmoosh Mohamed
- Banach Maciej
- Bandosz Piotr
- Banegas José R.
- Bao Tran Quoc
- Barbagallo Carlo M.
- BarcelĂł Alberto
- BaretiÄ Maja
- Barrera Lena
- Basit Abdul
- Batieha Anwar M.
- Batista Aline P.
- Baur Louise A.
- Belavendra Antonisamy
- Benchekor Sounnia Mediene
- Benet Mikhail
- Bennett James E.
- Berkinbayev Salim
- Bernabe- Ortiz Antonio
- Berrios Carrasola Ximena
- Bettiol HeloĂsa
- Beybey Augustin F.
- Bhargava Santosh K.
- Bika Lele Elysée Claude
- Bikbov Mukharram M.
- Bista Bihungum
- Bjerregaard Peter
- Bjertness Espen
- Bjertness Marius B.
- Björkelund Cecilia
- Bloch Katia V.
- Blokstra Anneke
- Bo Simona
- Bobak Martin
- Boggia Jose G.
- Bonaccio Marialaura
- Bonilla-Vargas Alice
- Borghs Herman
- Bovet Pascal
- Brajkovich Imperia
- Brenner Hermann
- Brewster Lizzy M.
- Brian Garry R.
- Briceño Yajaira
- Brito Miguel
- Bugge Anna
- Buntinx Frank
- Cabrera de LeĂłn Antonio
- Caixeta Roberta B.
- Can GĂŒnay
- Capanzana Mario V.
- Capuano Eduardo
- Capuano Rocco
- Capuano Vincenzo
- Cardoso Viviane C.
- Carlsson Axel C.
- Carrillo-Larco Rodrigo M.
- Casanueva Felipe F.
- Censi Laura
- CervantesâLoaiza Marvin
- Chamnan Parinya
- Chamukuttan Snehalatha
- Chan Queenie
- Charchar Fadi J.
- Chaturvedi Nish
- Chen Huashuai
- Cheraghian Bahman
- Chirlaque MarĂa-Dolores
- Chudek Jerzy
- Cifkova Renata
- Cirillo Massimo
- Claessens Frank
- Cohen Emmanuel
- Concin Hans
- Cooper Cyrus
- Costanzo Simona
- Cowan Melanie J.
- Cowell Chris
- Crujeiras Ana B.
- Cruz Juan J.
- Cureau Felipe V.
- Cuschieri Sarah
- CĂąndido Ana Paula C.
- Dallongeville Jean
- Damasceno Albertino
- Danaei Goodarz
- Dastgiri Saeed
- Davletov Kairat
- De Curtis Amalia
- de Gaetano Giovanni
- De Henauw Stefaan
- Deepa Mohan
- DeGennaro Vincent Jr
- Demarest Stefaan
- Dennison Elaine
- Deschamps Valérie
- Dhimal Meghnath
- Dika Zivka
- Djalalinia Shirin
- Donfrancesco Chiara
- Dong Guanghui
- Dorobantu Maria
- dos Santos Henrique Rafael
- Dragano Nico
- Drygas Wojciech
- Du Yong
- Duante Charmaine A.
- Duboz Priscilla
- Dushpanova Anar
- Dziankowska-Zaborszczyk Elzbieta
- Dörr Marcus
- DâArrigo Graziella
- dâOrsi Eleonora
- Ebrahimi Narges
- Eddie Ricky
- Eftekhar Ebrahim
- Efthymiou Vasiliki
- Egbagbe Eruke E.
- Eghtesad Sareh
- El Ati Jalila
- El-Khateeb Mohammad
- Eldemire-Shearer Denise
- Elosua Roberto
- Enang Ofem
- Erasmus Rajiv T.
- Erbel Raimund
- Erem Cihangir
- Ergor Gul
- Eriksen Louise
- Eriksson Johan G.
- Esmaeili Ali
- Evans Roger G.
- Ezzati Majid
- Fakhradiyev Ildar
- Fall Caroline H.
- Faramarzi Elnaz
- Farjam Mojtaba
- Farzadfar Farshad
- Farzi Yosef
- Fawwad Asher
- Felix-Redondo Francisco J.
- Ferguson Trevor S.
- Fernåndez-Bergés Daniel
- Ferrari Marika
- Ferreccio Catterina
- Ferreira Haroldo S.
- Ferrer Eldridge
- Feskens Edith J. M.
- Flood David
- Forsner Maria
- Fosse Sandrine
- Fottrell Edward F.
- Fouad Heba M.
- Francis Damian K.
- Frontera Guillermo
- Furusawa Takuro
- Gaciong Zbigniew
- Garnett Sarah P.
- Gasull Magda
- Gazzinelli Andrea
- Gehring Ulrike
- Ghaderi Ebrahim
- Ghamari Hadi
- Ghanbari Ali
- Ghasemi Erfan
- Gheorghe-Fronea Oana-Florentina
- Ghimire Anup
- Gialluisi Alessandro
- Giampaoli Simona
- Gianfagna Francesco
- Gill Tiffany K.
- Gironella Glen
- Giwercman Aleksander
- Goltzman David
- Gomula Aleksandra
- Gonzalez Angel R.
- Gonzalez-Chica David A.
- Gonzalez-Gross Marcela
- GonzĂĄlez-Rivas Juan P.
- GonzĂĄlez-Villalpando Clicerio
- GonzĂĄlez-Villalpando MarĂa-Elena
- Gonçalves Helen
- Gonçalves Mauer
- Gottrand Frederic
- Grafnetter DuĆĄan
- Gregg Edward W.
- Grodzicki Tomasz
- GrĂžntved Anders
- Guerrero Ramiro
- Gujral Unjali P.
- Gupta Rajeev
- Gutierrez Laura
- Gwee Xinyi
- Haghshenas Rosa
- Hakimi Hamid
- Hambleton Ian R.
- Hamzeh Behrooz
- Hanekom Willem A.
- Hange Dominique
- Hantunen Sari
- Hao Jie
- Harooni Javad
- Hashemi-Shahri Seyed Mohammad
- Hata Jun
- Heap Rachel A.
- Heidemann Christin
- Herrala Sauli
- Herzig Karl-Heinz
- Heshmat Ramin
- Ho Sai Yin
- Holdsworth Michelle
- Homayounfar Reza
- Hopman Wilma M.
- Horimoto Andrea R. V. R.
- Hormiga Claudia
- Horta Bernardo L.
- Houti Leila
- Howitt Christina
- Htay Thein Thein
- Htet Aung Soe
- Huerta JosĂ© MarĂa
- Huisman Martijn
- Husseini Abdullatif
- Huybrechts Inge
- Iacoviello Licia
- Iakupova Ellina M.
- Iannone Anna G.
- Ijoma Chinwuba
- Imperatore Giuseppina
- Irazola Vilma E.
- Ishida Takafumi
- Isiguzo Godsent C.
- Islek Duygu
- Ittermann Till
- Iwasaki Masanori
- Jacobs Jeremy M.
- Jaddou Hashem Y.
- Jadoul Michel
- Jallow Bakary
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- Wong Norazizah Ibrahim
- Woodward Mark
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- Yaacob Nor Azwany
- Yan Li
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- Yoosefi Moein
- Yoshihara Akihiro
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- Yu Yu-Ling
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- Yusoff Ahmad Faudzi
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- Zamani Farhad
- Zambon Sabina
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- Zdrojewski Tomasz
- Zeljkovic Vrkic Tajana
- Zeng Yi
- Zhang Zhen-Yu
- Zholdin Bekbolat
- Zhou Bin
- Zimmet Paul
- Zitt Emanuel
- Zuñiga Cisneros Julio
- ÄapkovĂĄ NadÄĆŸda
- Ć alaj Sanja
- Publication venue
- Nature Publishing Group
- Publication date
- 01/01/2023
- Field of study
Fasting plasma glucose (FPG) and haemoglobin A1c (HbA1c) are both used to diagnose
diabetes, but may identify different people as having diabetes. We used data from 117
population-based studies and quantified, in different world regions, the prevalence of
diagnosed diabetes, and whether those who were previously undiagnosed and detected
as having diabetes in survey screening had elevated FPG, HbA1c, or both. We developed
prediction equations for estimating the probability that a person without previously
diagnosed diabetes, and at a specific level of FPG, had elevated HbA1c, and vice versa.
The age-standardised proportion of diabetes that was previously undiagnosed, and
detected in survey screening, ranged from 30% in the high-income western region to 66%
in south Asia. Among those with screen-detected diabetes with either test, the agestandardised
proportion who had elevated levels of both FPG and HbA1c was 29-39%
across regions; the remainder had discordant elevation of FPG or HbA1c. In most low- and
middle-income regions, isolated elevated HbA1c more common than isolated elevated
FPG. In these regions, the use of FPG alone may delay diabetes diagnosis and
underestimate diabetes prevalence. Our prediction equations help allocate finite
resources for measuring HbA1c to reduce the global gap in diabetes diagnosis and
surveillance.peer-reviewe
Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants.
- Author
- Abarca-Gomez Leandra
- Abdeen Ziad A.
- Abu-Rmeileh Niveen M.
- Acosta-Cazares Benjamin
- Adams Robert J.
- Aekplakorn Wichai
- Afsana Kaosar
- Afzal Shoaib
- Agdeppa Imelda A.
- Aghazadeh-Attari Javad
- Aguilar-Salinas Carlos A.
- Agyemang Charles
- Ahmad Noor Ani
- Ahmadi Ali
- Ahmadi Naser
- Ahmadi Nastaran
- Ahmadizar Fariba
- Ahmed Soheir H.
- Ahrens Wolfgang
- Ajlouni Kamel
- Al Nsour Mohannad
- Al-Raddadi Rajaa
- Alarouj Monira
- AlBuhairan Fadia
- AlDhukair Shahla
- Ali Mohamed M.
- Alkandari Abdullah
- Alkerwi Ala'a
- Allin Kristine
- Aly Eman
- Amarapurkar Deepak N.
- Amougou Norbert
- Amouyel Philippe
- Andersen Lars Bo
- Anderssen Sigmund A.
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- Anjana Ranjit Mohan
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- Viswanathan Bharathi
- Vlasoff Tiina
- Vollenweider Peter
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- Wade Alisha N.
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- Wambiya Elvis O. A.
- Wanderley Junior Rildo de Souza
- Wang Ming-Dong
- Wang Ningli
- Wang Qian
- Wang Xiangjun
- Wang Ya Xing
- Wang Ying-Wei
- Wannamethee S. Goya
- Wareham Nicholas
- Wei Wenbin
- Weres Aneta
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- Whincup Peter H.
- Widhalm Kurt
- Widyahening Indah S.
- Widyahening Indah S.
- Wiecek Andrzej
- Wilks Rainford J.
- Willeit Johann
- Willeit Peter
- Williams Emmanuel A.
- Wilsgaard Tom
- Wojtyniak Bogdan
- Wong Andrew
- Wong Norazizah Ibrahim
- Wong Tien Yin
- Wong-McClure Roy A.
- Woo Jean
- Woodward Mark
- Woodward Mark
- Wu Frederick C.
- Wu Shouling
- Wyszynska Justyna
- Xu Haiquan
- Xu Liang
- Yaacob Nor Azwany
- Yan Weili
- Yang Ling
- Yang Xiaoguang
- Yang Yang
- Yasuharu Tabara
- Ye Xingwang
- Yiallouros Panayiotis K.
- Yoosefi Moein
- Yoshihara Akihiro
- You San-Lin
- Younger-Coleman Novie O.
- Yusoff Ahmad Faudzi
- Yusoff Muhammad Fadhli Mohd
- Zainuddin Ahmad A.
- Zakavi Seyed Rasoul
- Zamani Farhad
- Zambon Sabina
- Zampelas Antonis
- Zaw Ko Ko
- Zdrojewski Tomasz
- Zdrojewski Tomasz
- Zejglicova Kristyna
- Zeng Yi
- Zhang Luxia
- Zhang Zhen-Yu
- Zhao Dong
- Zhao Ming-Hui
- Zhen Shiqi
- Zheng Yingfeng
- Zholdin Bekbolat
- Zhou Bin
- Zhu Dan
- Zins Marie
- Zitt Emanuel
- Zocalo Yanina
- Zoghlami Nada
- Zuniga Cisneros Julio
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2021
- Field of study
BACKGROUND: Hypertension can be detected at the primary health-care level and low-cost treatments can effectively control hypertension. We aimed to measure the prevalence of hypertension and progress in its detection, treatment, and control from 1990 to 2019 for 200 countries and territories. METHODS: We used data from 1990 to 2019 on people aged 30-79 years from population-representative studies with measurement of blood pressure and data on blood pressure treatment. We defined hypertension as having systolic blood pressure 140 mm Hg or greater, diastolic blood pressure 90 mm Hg or greater, or taking medication for hypertension. We applied a Bayesian hierarchical model to estimate the prevalence of hypertension and the proportion of people with hypertension who had a previous diagnosis (detection), who were taking medication for hypertension (treatment), and whose hypertension was controlled to below 140/90 mm Hg (control). The model allowed for trends over time to be non-linear and to vary by age. FINDINGS: The number of people aged 30-79 years with hypertension doubled from 1990 to 2019, from 331 (95% credible interval 306-359) million women and 317 (292-344) million men in 1990 to 626 (584-668) million women and 652 (604-698) million men in 2019, despite stable global age-standardised prevalence. In 2019, age-standardised hypertension prevalence was lowest in Canada and Peru for both men and women; in Taiwan, South Korea, Japan, and some countries in western Europe including Switzerland, Spain, and the UK for women; and in several low-income and middle-income countries such as Eritrea, Bangladesh, Ethiopia, and Solomon Islands for men. Hypertension prevalence surpassed 50% for women in two countries and men in nine countries, in central and eastern Europe, central Asia, Oceania, and Latin America. Globally, 59% (55-62) of women and 49% (46-52) of men with hypertension reported a previous diagnosis of hypertension in 2019, and 47% (43-51) of women and 38% (35-41) of men were treated. Control rates among people with hypertension in 2019 were 23% (20-27) for women and 18% (16-21) for men. In 2019, treatment and control rates were highest in South Korea, Canada, and Iceland (treatment >70%; control >50%), followed by the USA, Costa Rica, Germany, Portugal, and Taiwan. Treatment rates were less than 25% for women and less than 20% for men in Nepal, Indonesia, and some countries in sub-Saharan Africa and Oceania. Control rates were below 10% for women and men in these countries and for men in some countries in north Africa, central and south Asia, and eastern Europe. Treatment and control rates have improved in most countries since 1990, but we found little change in most countries in sub-Saharan Africa and Oceania. Improvements were largest in high-income countries, central Europe, and some upper-middle-income and recently high-income countries including Costa Rica, Taiwan, Kazakhstan, South Africa, Brazil, Chile, Turkey, and Iran. INTERPRETATION: Improvements in the detection, treatment, and control of hypertension have varied substantially across countries, with some middle-income countries now outperforming most high-income nations. The dual approach of reducing hypertension prevalence through primary prevention and enhancing its treatment and control is achievable not only in high-income countries but also in low-income and middle-income settings. FUNDING: WHO
Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants
- Author
- Abarca-Gomez Leandra
- Abdeen Ziad A.
- Abu-Rmeileh Niveen M.
- Acosta-Cazares Benjamin
- Adams Robert J.
- Aekplakorn Wichai
- Afsana Kaosar
- Afzal Shoaib
- Agdeppa Imelda A.
- Aghazadeh-Attari Javad
- Aguilar-Salinas Carlos A.
- Agyemang Charles
- Ahmad Noor Ani
- Ahmadi Ali
- Ahmadi Naser
- Ahmadi Nastaran
- Ahmadizar Fariba
- Ahmed Soheir H.
- Ahrens Wolfgang
- Ajlouni Kamel
- Al Nsour Mohannad
- Al-Raddadi Rajaa
- Alarouj Monira
- AlBuhairan Fadia
- AlDhukair Shahla
- Ali Mohamed M.
- Alkandari Abdullah
- Alkerwi Ala'a
- Allin Kristine
- Aly Eman
- Amarapurkar Deepak N.
- Amougou Norbert
- Amouyel Philippe
- Andersen Lars Bo
- Anderssen Sigmund A.
- Andre Moura-dos-Santos Marcos
- Anjana Ranjit Mohan
- Ansari-Moghaddam Alireza
- Ansong Daniel
- Aounallah-Skhiri Hajer
- Araujo Joana
- Ariansen Inger
- Aris Tahir
- Arku Raphael E.
- Arlappa Nimmathota
- Aryal Krishna K.
- Aspelund Thor
- Assah Felix K.
- Assuncao Maria Cecilia F.
- Auvinen Juha
- Avdicova Maria
- Azevedo Ana
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- Stokwiszewski Jakub
- Stronks Karien
- Strufaldi Maria Wany
- Suka Machi
- Sun Chien-An
- Sundstrom Johan
- Sundstrom Johan
- Sung Yn-Tz
- Suriyawongpaisal Paibul
- Sy Rody G.
- Syddall Holly E.
- Sylva Rene Charles
- Szklo Moyses
- Tai E. Shyong
- Tammesoo Mari-Liis
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- Tarawneh Mohammed Rasoul
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- Taylor Anne
- Taylor Julie
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- Tell Grethe S.
- Tello Tania
- Tham Yih Chung
- Thankappan K. R.
- Theobald Holger
- Theodoridis Xenophon
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- Tuomainen Tomi-Pekka
- Tuomilehto Jaakko
- Turley Maria L.
- Twig Gilad
- Tynelius Per
- Tzourio Christophe
- Ueda Peter
- Ugel Eunice
- Ulmer Hanno
- Uusitalo Hannu M. T.
- Valdivia Gonzalo
- Valvi Damaskini
- van Dam Rob M.
- van den Born Bert-Jan
- Van der Heyden Johan
- van der Schouw Yvonne T.
- Van Herck Koen
- Van Schoor Natasja M.
- van Valkengoed Irene G. M.
- van Zutphen Elisabeth M.
- Vanderschueren Dirk
- Vanuzzo Diego
- Varbo Anette
- Varghese Cherian
- Vasan Senthil K.
- Vega Tomas
- Veidebaum Toomas
- Velasquez-Melendez Gustavo
- Veronesi Giovanni
- Verschuren W. M. Monique
- Verstraeten Roosmarijn
- Victora Cesar G.
- Viet Lucie
- Villalpando Salvador
- Vineis Paolo
- Vioque Jesus
- Virtanen Jyrki K.
- Visvikis-Siest Sophie
- Viswanathan Bharathi
- Vlasoff Tiina
- Vollenweider Peter
- Voutilainen Ari
- Vrkic Tajana Zeljkovic
- Wade Alisha N.
- Walton Janette
- Wambiya Elvis O. A.
- Wanderley Junior Rildo de Souza
- Wang Ming-Dong
- Wang Ningli
- Wang Qian
- Wang Xiangjun
- Wang Ya Xing
- Wang Ying-Wei
- Wannamethee S. Goya
- Wareham Nicholas
- Wei Wenbin
- Weres Aneta
- Werner Bo
- Whincup Peter H.
- Widhalm Kurt
- Widyahening Indah S.
- Widyahening Indah S.
- Wiecek Andrzej
- Wilks Rainford J.
- Willeit Johann
- Willeit Peter
- Williams Emmanuel A.
- Wilsgaard Tom
- Wojtyniak Bogdan
- Wong Andrew
- Wong Norazizah Ibrahim
- Wong Tien Yin
- Wong-McClure Roy A.
- Woo Jean
- Woodward Mark
- Woodward Mark
- Wu Frederick C.
- Wu Shouling
- Wyszynska Justyna
- Xu Haiquan
- Xu Liang
- Yaacob Nor Azwany
- Yan Weili
- Yang Ling
- Yang Xiaoguang
- Yang Yang
- Yasuharu Tabara
- Ye Xingwang
- Yiallouros Panayiotis K.
- Yoosefi Moein
- Yoshihara Akihiro
- You San-Lin
- Younger-Coleman Novie O.
- Yusoff Ahmad Faudzi
- Yusoff Muhammad Fadhli Mohd
- Zainuddin Ahmad A.
- Zakavi Seyed Rasoul
- Zamani Farhad
- Zambon Sabina
- Zampelas Antonis
- Zaw Ko Ko
- Zdrojewski Tomasz
- Zdrojewski Tomasz
- Zejglicova Kristyna
- Zeng Yi
- Zhang Luxia
- Zhang Zhen-Yu
- Zhao Dong
- Zhao Ming-Hui
- Zhen Shiqi
- Zheng Yingfeng
- Zholdin Bekbolat
- Zhou Bin
- Zhu Dan
- Zins Marie
- Zitt Emanuel
- Zocalo Yanina
- Zoghlami Nada
- Zuniga Cisneros Julio
- Publication venue
- ELSEVIER SCIENCE INC
- Publication date
- 01/01/2021
- Field of study
Background Hypertension can be detected at the primary health-care level and low-cost treatments can effectively control hypertension. We aimed to measure the prevalence of hypertension and progress in its detection, treatment, and control from 1990 to 2019 for 200 countries and territories. Methods We used data from 1990 to 2019 on people aged 30-79 years from population-representative studies with measurement of blood pressure and data on blood pressure treatment. We defined hypertension as having systolic blood pressure 140 mm Hg or greater, diastolic blood pressure 90 mm Hg or greater, or taking medication for hypertension. We applied a Bayesian hierarchical model to estimate the prevalence of hypertension and the proportion of people with hypertension who had a previous diagnosis (detection), who were taking medication for hypertension (treatment), and whose hypertension was controlled to below 140/90 mm Hg (control). The model allowed for trends over time to be non-linear and to vary by age. Findings The number of people aged 30-79 years with hypertension doubled from 1990 to 2019, from 331 (95% credible interval 306-359) million women and 317 (292-344) million men in 1990 to 626 (584-668) million women and 652 (604-698) million men in 2019, despite stable global age-standardised prevalence. In 2019, age-standardised hypertension prevalence was lowest in Canada and Peru for both men and women; in Taiwan, South Korea, Japan, and some countries in western Europe including Switzerland, Spain, and the UK for women; and in several low-income and middle-income countries such as Eritrea, Bangladesh, Ethiopia, and Solomon Islands for men. Hypertension prevalence surpassed 50% for women in two countries and men in nine countries, in central and eastern Europe, central Asia, Oceania, and Latin America. Globally, 59% (55-62) of women and 49% (46-52) of men with hypertension reported a previous diagnosis of hypertension in 2019, and 47% (43-51) of women and 38% (35-41) of men were treated. Control rates among people with hypertension in 2019 were 23% (20-27) for women and 18% (16-21) for men. In 2019, treatment and control rates were highest in South Korea, Canada, and Iceland (treatment >70%; control >50%), followed by the USA, Costa Rica, Germany, Portugal, and Taiwan. Treatment rates were less than 25% for women and less than 20% for men in Nepal, Indonesia, and some countries in sub-Saharan Africa and Oceania. Control rates were below 10% for women and men in these countries and for men in some countries in north Africa, central and south Asia, and eastern Europe. Treatment and control rates have improved in most countries since 1990, but we found little change in most countries in sub-Saharan Africa and Oceania. Improvements were largest in high-income countries, central Europe, and some upper-middle-income and recently high-income countries including Costa Rica, Taiwan, Kazakhstan, South Africa, Brazil, Chile, Turkey, and Iran. Interpretation Improvements in the detection, treatment, and control of hypertension have varied substantially across countries, with some middle-income countries now outperforming most high-income nations. The dual approach of reducing hypertension prevalence through primary prevention and enhancing its treatment and control is achievable not only in high-income countries but also in low-income and middle-income settings. Copyright (C) 2021 World Health Organization; licensee Elsevier
Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants
- Author
- Abarca-Gomez Leandra
- Abdeen Ziad A.
- Abu-Rmeileh Niveen M.
- Acosta-Cazares Benjamin
- Adams Robert J.
- Aekplakorn Wichai
- Afsana Kaosar
- Afzal Shoaib
- Agdeppa Imelda A.
- Aghazadeh-Attari Javad
- Aguilar-Salinas Carlos A.
- Agyemang Charles
- Ahmad Noor Ani
- Ahmadi Ali
- Ahmadi Naser
- Ahmadi Nastaran
- Ahmadizar Fariba
- Ahmed Soheir H.
- Ahrens Wolfgang
- Ajlouni Kamel
- Al Nsour Mohannad
- Al-Raddadi Rajaa
- Alarouj Monira
- AlBuhairan Fadia
- AlDhukair Shahla
- Ali Mohamed M.
- Alkandari Abdullah
- Alkerwi Ala'a
- Allin Kristine
- Aly Eman
- Amarapurkar Deepak N.
- Amougou Norbert
- Amouyel Philippe
- Andersen Lars Bo
- Anderssen Sigmund A.
- Andre Moura-dos-Santos Marcos
- Anjana Ranjit Mohan
- Ansari-Moghaddam Alireza
- Ansong Daniel
- Aounallah-Skhiri Hajer
- Araujo Joana
- Ariansen Inger
- Aris Tahir
- Arku Raphael E.
- Arlappa Nimmathota
- Aryal Krishna K.
- Aspelund Thor
- Assah Felix K.
- Assuncao Maria Cecilia F.
- Auvinen Juha
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- Azevedo Ana
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- Babu Bontha V.
- Bahijri Suhad
- Balakrishna Nagalla
- Balanova Yulia
- Balanova Yulia
- Bamoshmoosh Mohamed
- Banach Maciej
- Banadinovic Maja
- Bandosz Piotr
- Banegas Jose R.
- Baran Joanna
- Barbagallo Carlo M.
- Barcelo Alberto
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- Voutilainen Ari
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- Wambiya Elvis O. A.
- Wanderley Junior Rildo de Souza
- Wang Ming-Dong
- Wang Ningli
- Wang Qian
- Wang Xiangjun
- Wang Ya Xing
- Wang Ying-Wei
- Wannamethee S. Goya
- Wareham Nicholas
- Wei Wenbin
- Weres Aneta
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- Whincup Peter H.
- Widhalm Kurt
- Widyahening Indah S.
- Widyahening Indah S.
- Wiecek Andrzej
- Wilks Rainford J.
- Willeit Johann
- Willeit Peter
- Williams Emmanuel A.
- Wilsgaard Tom
- Wojtyniak Bogdan
- Wong Andrew
- Wong Norazizah Ibrahim
- Wong Tien Yin
- Wong-McClure Roy A.
- Woo Jean
- Woodward Mark
- Woodward Mark
- Wu Frederick C.
- Wu Shouling
- Wyszynska Justyna
- Xu Haiquan
- Xu Liang
- Yaacob Nor Azwany
- Yan Weili
- Yang Ling
- Yang Xiaoguang
- Yang Yang
- Yasuharu Tabara
- Ye Xingwang
- Yiallouros Panayiotis K.
- Yoosefi Moein
- Yoshihara Akihiro
- You San-Lin
- Younger-Coleman Novie O.
- Yusoff Ahmad Faudzi
- Yusoff Muhammad Fadhli Mohd
- Zainuddin Ahmad A.
- Zakavi Seyed Rasoul
- Zamani Farhad
- Zambon Sabina
- Zampelas Antonis
- Zaw Ko Ko
- Zdrojewski Tomasz
- Zdrojewski Tomasz
- Zejglicova Kristyna
- Zeng Yi
- Zhang Luxia
- Zhang Zhen-Yu
- Zhao Dong
- Zhao Ming-Hui
- Zhen Shiqi
- Zheng Yingfeng
- Zholdin Bekbolat
- Zhou Bin
- Zhu Dan
- Zins Marie
- Zitt Emanuel
- Zocalo Yanina
- Zoghlami Nada
- Zuniga Cisneros Julio
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2021
- Field of study
Background
Hypertension can be detected at the primary health-care level and low-cost treatments can effectively control hypertension. We aimed to measure the prevalence of hypertension and progress in its detection, treatment, and control from 1990 to 2019 for 200 countries and territories.
Methods
We used data from 1990 to 2019 on people aged 30â79 years from population-representative studies with measurement of blood pressure and data on blood pressure treatment. We defined hypertension as having systolic blood pressure 140 mm Hg or greater, diastolic blood pressure 90 mm Hg or greater, or taking medication for hypertension. We applied a Bayesian hierarchical model to estimate the prevalence of hypertension and the proportion of people with hypertension who had a previous diagnosis (detection), who were taking medication for hypertension (treatment), and whose hypertension was controlled to below 140/90 mm Hg (control). The model allowed for trends over time to be non-linear and to vary by age.
Findings
The number of people aged 30â79 years with hypertension doubled from 1990 to 2019, from 331 (95% credible interval 306â359) million women and 317 (292â344) million men in 1990 to 626 (584â668) million women and 652 (604â698) million men in 2019, despite stable global age-standardised prevalence. In 2019, age-standardised hypertension prevalence was lowest in Canada and Peru for both men and women; in Taiwan, South Korea, Japan, and some countries in western Europe including Switzerland, Spain, and the UK for women; and in several low-income and middle-income countries such as Eritrea, Bangladesh, Ethiopia, and Solomon Islands for men. Hypertension prevalence surpassed 50% for women in two countries and men in nine countries, in central and eastern Europe, central Asia, Oceania, and Latin America. Globally, 59% (55â62) of women and 49% (46â52) of men with hypertension reported a previous diagnosis of hypertension in 2019, and 47% (43â51) of women and 38% (35â41) of men were treated. Control rates among people with hypertension in 2019 were 23% (20â27) for women and 18% (16â21) for men. In 2019, treatment and control rates were highest in South Korea, Canada, and Iceland (treatment >70%; control >50%), followed by the USA, Costa Rica, Germany, Portugal, and Taiwan. Treatment rates were less than 25% for women and less than 20% for men in Nepal, Indonesia, and some countries in sub-Saharan Africa and Oceania. Control rates were below 10% for women and men in these countries and for men in some countries in north Africa, central and south Asia, and eastern Europe. Treatment and control rates have improved in most countries since 1990, but we found little change in most countries in sub-Saharan Africa and Oceania. Improvements were largest in high-income countries, central Europe, and some upper-middle-income and recently high-income countries including Costa Rica, Taiwan, Kazakhstan, South Africa, Brazil, Chile, Turkey, and Iran.
Interpretation
Improvements in the detection, treatment, and control of hypertension have varied substantially across countries, with some middle-income countries now outperforming most high-income nations. The dual approach of reducing hypertension prevalence through primary prevention and enhancing its treatment and control is achievable not only in high-income countries but also in low-income and middle-income settings
Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants
- Author
- Abarca-GĂłmez Leandra
- Abdeen Ziad A
- Abdul Rahim Hanan F
- Abu-Rmeileh Niveen M
- Acosta-Cazares Benjamin
- Adams Robert J
- Aekplakorn Wichai
- Afsana Kaosar
- Afzal Shoaib
- Agdeppa Imelda A
- Aghazadeh-Attari Javad
- Aguilar-Salinas Carlos A
- Agyemang Charles
- Ahmad Noor Ani
- Ahmadi Ali
- Ahmadi Naser
- Ahmadi Nastaran
- Ahmadizar Fariba
- Ahmed Soheir H
- Ahrens Wolfgang
- Ajlouni Kamel
- Al-Raddadi Rajaa
- Alarouj Monira
- AlBuhairan Fadia
- AlDhukair Shahla
- Ali Mohamed M
- Alkandari Abdullah
- Alkerwi Ala'a
- Allin Kristine
- Aly Eman
- Amarapurkar Deepak N
- Amougou Norbert
- Amouyel Philippe
- Andersen Lars Bo
- Anderssen Sigmund A
- Anjana Ranjit Mohan
- Ansari-Moghaddam Alireza
- Ansong Daniel
- Aounallah-Skhiri Hajer
- AraĂșjo Joana
- Ariansen Inger
- Aris Tahir
- Arku Raphael E
- Arlappa Nimmathota
- Aryal Krishna K
- Aspelund Thor
- Assah Felix K
- Assunção Maria CecĂlia F
- Auvinen Juha
- AvdiÄovĂĄ MĂĄria
- Azevedo Ana
- Azimi-Nezhad Mohsen
- Azizi Fereidoun
- Azmin Mehrdad
- Babu Bontha V
- Bahijri Suhad
- Balakrishna Nagalla
- Balanova Yulia
- Bamoshmoosh Mohamed
- Banach Maciej
- BanadinoviÄ Maja
- Bandosz Piotr
- Banegas José R
- Baran Joanna
- Barbagallo Carlo M
- BarcelĂł Alberto
- Barkat Amina
- Barreto Marta
- Barros Aluisio JD
- Barros Mauro VirgĂlio Gomes
- Bartosiewicz Anna
- Basit Abdul
- Bastos Joao Luiz D
- Bata Iqbal
- Batieha Anwar M
- Batyrbek Assembekov
- Baur Louise A
- Beaglehole Robert
- Belavendra Antonisamy
- Ben Romdhane Habiba
- Benet Mikhail
- Bennett James E
- Benson Lowell S
- Berkinbayev Salim
- Bernabe-Ortiz Antonio
- Bernotiene Gailute
- Bettiol HeloĂsa
- Bezerra Jorge
- Bhagyalaxmi Aroor
- Bhargava Santosh K
- Bia Daniel
- Biasch Katia
- Bika Lele Elysée Claude
- Bikbov Mukharram M
- Bista Bihungum
- Bjerregaard Peter
- Bjertness Espen
- Bjertness Marius B
- Björkelund Cecilia
- Bloch Katia V
- Blokstra Anneke
- Bo Simona
- Bobak Martin
- Boeing Heiner
- Boggia Jose G
- Boissonnet Carlos P
- Bojesen Stig E
- Bongard Vanina
- Bonilla-Vargas Alice
- Bopp Matthias
- Borghs Herman
- Bovet Pascal
- Boyer Christopher B
- Braeckman Lutgart
- Brajkovich Imperia
- Branca Francesco
- Breckenkamp Juergen
- Brenner Hermann
- Brewster Lizzy M
- Briceño Yajaira
- Brito Miguel
- Bruno Graziella
- Bueno Gloria
- Bueno-de-Mesquita H Bas
- Bugge Anna
- Burns Con
- Bursztyn Michael
- Cabrera de LeĂłn Antonio
- Cacciottolo Joseph
- Cameron Christine
- Can GĂŒnay
- Capanzana Mario V
- Capuano Eduardo
- Capuano Vincenzo
- Cardoso Viviane C
- Carlsson Axel C
- Carrillo-Larco Rodrigo M
- Carvalho Joana
- Casanueva Felipe F
- Censi Laura
- Cervantes-Loaiza Marvin
- Chadjigeorgiou Charalambos A
- Chamukuttan Snehalatha
- Chan Angelique W
- Chan Queenie
- Chaturvedi Himanshu K
- Chaturvedi Nish
- Chee Miao Li
- Chen Chien-Jen
- Chen Fangfang
- Chen Huashuai
- Chen Shuohua
- Chen Zhengming
- Cheng Ching-Yu
- Cheraghian Bahman
- Cherkaoui Dekkaki Imane
- Chetrit Angela
- Chien Kuo-Liong
- Chiolero Arnaud
- Chiou Shu-Ti
- Chirita-Emandi Adela
- Chirlaque MarĂa-Dolores
- Cho Belong
- Christensen Kaare
- Christofaro Diego G
- Chudek Jerzy
- Cifkova Renata
- Cinteza Eliza
- Claessens Frank
- Clarke Janine
- Clays Els
- Cohen Emmanuel
- Concin Hans
- Cooper Cyrus
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- Costanzo Simona
- Cottel Dominique
- Cowan Melanie J
- Cowell Chris
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- Crampin Amelia C
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- Csilla SemĂĄnovĂĄ
- Cui Liufu
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- Cuschieri Sarah
- CĂąndido Ana Paula C
- D'Arrigo Graziella
- d'Orsi Eleonora
- Dallongeville Jean
- Damasceno Albertino
- Danaei Goodarz
- Dankner Rachel
- Dantoft Thomas M
- Dauchet Luc
- Davletov Kairat
- De Backer Guy
- De Bacquer Dirk
- De Curtis Amalia
- de Gaetano Giovanni
- De Henauw Stefaan
- de Oliveira Paula Duarte
- De Ridder David
- De Smedt Delphine
- Deepa Mohan
- Deev Alexander D
- DeGennaro Vincent Jr
- Delisle HĂ©lĂšne
- Demarest Stefaan
- Dennison Elaine
- Deschamps Valérie
- Dhimal Meghnath
- Di Castelnuovo Augusto F
- Dias-da-Costa Juvenal Soares
- Diaz Alejandro
- Dickerson Ty T
- Dika Zivka
- Djalalinia Shirin
- Do Ha TP
- Dobson Annette J
- Donfrancesco Chiara
- Donoso Silvana P
- Dorobantu Maria
- Doua Kouamelan
- Dragano Nico
- Drygas Wojciech
- Duante Charmaine A
- Duboz Priscilla
- Duda Rosemary B
- Dulskiene Virginija
- Dushpanova Anar
- Dzerve Vilnis
- Dziankowska-Zaborszczyk Elzbieta
- Döring Angela
- Dörr Marcus
- DĆŸakula Aleksandar
- Eddie Ricky
- Eftekhar Ebrahim
- Eggertsen Robert
- Eghtesad Sareh
- Eiben Gabriele
- Ekelund Ulf
- El Ati Jalila
- El-Khateeb Mohammad
- Eldemire-Shearer Denise
- Eliasen Marie
- Elliott Paul
- Elosua Roberto
- Erasmus Rajiv T
- Erbel Raimund
- Erem Cihangir
- Eriksen Louise
- Eriksson Johan G
- Escobedo-de la Peña Jorge
- Eslami Saeid
- Esmaeili Ali
- Evans Alun
- Ezzati Majid
- Faeh David
- Fakhretdinova Albina A
- Fall Caroline H
- Faramarzi Elnaz
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- Farzadfar Farshad
- Fattahi Mohammad Reza
- Fawwad Asher
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- Felix-Redondo Francisco J
- Ferguson Trevor S
- Fernandes Romulo A
- Fernåndez-Bergés Daniel
- Ferrante Daniel
- Ferrao Thomas
- Ferrari Marika
- Ferrario Marco M
- Ferreccio Catterina
- Ferreira Haroldo S
- Ferrer Eldridge
- Ferrieres Jean
- FigueirĂł Thamara Hubler
- Fink GĂŒnther
- Fischer Krista
- Foo Leng Huat
- Forsner Maria
- Fouad Heba M
- Francis Damian K
- Franco Maria do Carmo
- Frikke-Schmidt Ruth
- Frontera Guillermo
- Fuchs Flavio D
- Fuchs Sandra C
- Fujita Yuki
- Fumihiko Matsuda
- Furdela Viktoriya
- Furer Ariel
- Furusawa Takuro
- Gaciong Zbigniew
- Galbarczyk Andrzej
- Galenkamp Henrike
- Galvano Fabio
- Gao Jingli
- Gao Pei
- Garcia Pablo
- Garcia-de-la-Hera Manoli
- Gareta Dickman
- Garnett Sarah P
- Gaspoz Jean-Michel
- Gasull Magda
- Gazzinelli Andrea
- Gehring Ulrike
- Geleijnse Johanna M
- George Ronnie
- Ghanbari Ali
- Ghasemi Erfan
- Gheorghe-Fronea Oana-Florentina
- Ghimire Anup
- Gialluisi Alessandro
- Giampaoli Simona
- Gieger Christian
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- Giovannelli Jonathan
- Gironella Glen
- Giwercman Aleksander
- Gkiouras Konstantinos
- Goldberg Marcel
- Goldsmith Rebecca A
- Gomez Luis F
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- Gonzalez-Chica David A
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- Gonçalves Helen
- Gonçalves Mauer
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- Gottrand Frederic
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- Tuomainen Tomi-Pekka
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- Villalpando Salvador
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- Wan Bebakar Wan Mohamad
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- Wanderley JĂșnior Rildo de Souza
- Wang Ming-Dong
- Wang Ningli
- Wang Qian
- Wang Xiangjun
- Wang Ya Xing
- Wang Ying-Wei
- Wannamethee S Goya
- Wareham Nicholas
- Wei Wenbin
- Weres Aneta
- Werner Bo
- Whincup Peter H
- Widhalm Kurt
- Widyahening Indah S
- Wiecek Andrzej
- Wilks Rainford J
- Willeit Johann
- Willeit Peter
- Williams Emmanuel A
- Wilsgaard Tom
- Wojtyniak Bogdan
- Wong Andrew
- Wong Tien Yin
- Wong-McClure Roy A
- Woo Jean
- Woodward Mark
- Wu Frederick C
- Wu Shouling
- Wyszynska Justyna
- Xu Haiquan
- Xu Liang
- Yaacob Nor Azwany
- Yan Weili
- Yang Ling
- Yang Xiaoguang
- Yang Yang
- Yasuharu Tabara
- Ye Xingwang
- Yiallouros Panayiotis K
- Yoosefi Moein
- Yoshihara Akihiro
- You San-Lin
- Younger-Coleman Novie O
- Yusoff Ahmad Faudzi
- Zainuddin Ahmad A
- Zakavi Seyed Rasoul
- Zamani Farhad
- Zambon Sabina
- Zampelas Antonis
- Zapata Maria Elisa
- Zaw Ko Ko
- Zdrojewski Tomasz
- Zejglicova Kristyna
- Zeljkovic Vrkic Tajana
- Zeng Yi
- Zhang Luxia
- Zhang Zhen-Yu
- Zhao Dong
- Zhao Ming-Hui
- Zhen Shiqi
- Zheng Yingfeng
- Zholdin Bekbolat
- Zhou Bin
- Zhu Dan
- Zins Marie
- Zitt Emanuel
- Zocalo Yanina
- Zoghlami Nada
- Zuñiga Cisneros Julio
- ÄapkovĂĄ NadÄĆŸda
- Publication venue
- 'Elsevier BV'
- Publication date
- 17/09/2021
- Field of study
Background
Hypertension can be detected at the primary health-care level and low-cost treatments can effectively control hypertension. We aimed to measure the prevalence of hypertension and progress in its detection, treatment, and control from 1990 to 2019 for 200 countries and territories.
Methods
We used data from 1990 to 2019 on people aged 30â79 years from population-representative studies with measurement of blood pressure and data on blood pressure treatment. We defined hypertension as having systolic blood pressure 140 mm Hg or greater, diastolic blood pressure 90 mm Hg or greater, or taking medication for hypertension. We applied a Bayesian hierarchical model to estimate the prevalence of hypertension and the proportion of people with hypertension who had a previous diagnosis (detection), who were taking medication for hypertension (treatment), and whose hypertension was controlled to below 140/90 mm Hg (control). The model allowed for trends over time to be non-linear and to vary by age.
Findings
The number of people aged 30â79 years with hypertension doubled from 1990 to 2019, from 331 (95% credible interval 306â359) million women and 317 (292â344) million men in 1990 to 626 (584â668) million women and 652 (604â698) million men in 2019, despite stable global age-standardised prevalence. In 2019, age-standardised hypertension prevalence was lowest in Canada and Peru for both men and women; in Taiwan, South Korea, Japan, and some countries in western Europe including Switzerland, Spain, and the UK for women; and in several low-income and middle-income countries such as Eritrea, Bangladesh, Ethiopia, and Solomon Islands for men. Hypertension prevalence surpassed 50% for women in two countries and men in nine countries, in central and eastern Europe, central Asia, Oceania, and Latin America. Globally, 59% (55â62) of women and 49% (46â52) of men with hypertension reported a previous diagnosis of hypertension in 2019, and 47% (43â51) of women and 38% (35â41) of men were treated. Control rates among people with hypertension in 2019 were 23% (20â27) for women and 18% (16â21) for men. In 2019, treatment and control rates were highest in South Korea, Canada, and Iceland (treatment >70%; control >50%), followed by the USA, Costa Rica, Germany, Portugal, and Taiwan. Treatment rates were less than 25% for women and less than 20% for men in Nepal, Indonesia, and some countries in sub-Saharan Africa and Oceania. Control rates were below 10% for women and men in these countries and for men in some countries in north Africa, central and south Asia, and eastern Europe. Treatment and control rates have improved in most countries since 1990, but we found little change in most countries in sub-Saharan Africa and Oceania. Improvements were largest in high-income countries, central Europe, and some upper-middle-income and recently high-income countries including Costa Rica, Taiwan, Kazakhstan, South Africa, Brazil, Chile, Turkey, and Iran.
Interpretation
Improvements in the detection, treatment, and control of hypertension have varied substantially across countries, with some middle-income countries now outperforming most high-income nations. The dual approach of reducing hypertension prevalence through primary prevention and enhancing its treatment and control is achievable not only in high-income countries but also in low-income and middle-income settings
Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries
- Author
- Abad-Motos Ane
- Abbas Ahmed M.
- Abbas Mostafa
- Abbasi Mujeeb
- Abbott Tom
- Abd Karim Muhammad Fairuz Shah
- Abdalaal Ibrahim
- Abdel-Galil Khalid
- Abdelemam Rania
- Abdelgawad Abdalrahman
- Abdelkarim Maryam
- Abdelkhalek Mohamed
- Abdelmageed Abdelfatah
- Abdelmawgoud Sherif
- Abdelmohsen Sarah
- Abdelrahman Ahmed Saber
- Abdelrahman Mostafa
- Abdelwahab Khaled
- Abdou Hossam
- Abdulai Darling Ramatu
- Abdulkhaleq Marwa
- Abdullah Bahiyah
- Abdulsalam Khalifa
- Abdulsalam Shuaib
- Abdur-Rahman Lukman
- Abdus-Salam Rukiyat
- Abdussalam Hameedat Opeyemi
- Abebrese John Tabiri
- Abeldaño Ariel
- Abou-Khalil Jad
- Abou-Taleb Hisham
- Abozid Anwaar
- Abozied Hesham
- Abrate Alberto
- Abu-Zaid Ahmed
- Abubakar Mohammed Kabir
- Abud Burçin
- Abuzaid Mohammed
- Adam Albushra Altayeb
- Adamina Michel
- Adamou Harissou
- Adamu Auwal
- Adamu Kabir Musa
- Adanu Kekeli
- Adebara Idowu
- Adebola Oluwaseyi
- Ademuyiwa Adesoji
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- GĂłmez Mercedes Estaire
- GönĂŒllĂŒ Emre
- Habeeb Olufemi
- Habeebullah Alaa
- Hadaya Joseph
- Haddad Ahmad
- Haddud Abdurrahman
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- Hailu Samuel
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- Hamdan Qusai
- Hameed Bm Zeeshan
- Hamid Hytham K. S.
- Hamida Baha Ben
- Hamill James
- Hammond Bernard
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- Hardcastle Timothy
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- Ho Ken Weixing
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- Hooker Robert
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- Horwell Edward
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- Huatuco René Manuel Palacios
- Hughes Isabel
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- Katsura Morihiro
- Kauppila Joonas H
- Kaur Amanjot
- Kausar Nabila
- Kavalakat Alfie
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- Kealey Joshua
- Kebede Ephrem
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- Kennerton A.S.
- Kent Alistair J
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- KoĆĄir Jurij AleĆĄ
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- Kroon Hidde M.
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- Laborde Mario Mella
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- LaganĂ Antonio Simone
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- Leonard Laura
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- Li Elizabeth
- Li Zoe
- Liakakos Theodore
- Liang Rhea
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- Locatello Luca Giovanni
- Lohmann Tibor Karl
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- Luc Jessica
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- Lyra Humberto Fenner
- Mabood Waleed
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- MacHain V Gustavo Miguel
- MacHairas Nikolaos
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- Maffuz-Aziz Antonio
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- Magnone Stefano
- Magouliotis Dimitrios
- Maguire Patrick J.
- MaheÄiÄ Tina TomiÄ
- Mahmood Fahad
- Mahmoud Abdelrahman
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- Mallmann Christoph
- Mallmann Michael R.
- Mambrilla Sara
- Manangi Mallikarjuna
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- Maniaci Antonino
- Manickavasagam Jaiganesh
- Manigrasso Michele
- Manjula S.
- Mannan Syed
- Mantziari Styliani
- MaquilĂłn Alejandra Jara
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- Martins Ana
- Martins Claudia Pinto
- Martins Paulo N.
- MartĂnez Daniel FernĂĄndez
- MartĂnez Eunate Ganuza
- MartĂnez VerĂłnica MartĂn
- MartĂnez-SĂĄnchez Marta Isabel
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- Massoud John
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- Matthews Emily
- Mauriello Claudio
- Maurus Christine
- Mayer Horacio F.
- Mayo-Yåñez Miguel
- Mazzarella Gennaro
- Mbodi Langanani
- Mbwele Bernard
- McAleer Stephen
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- McGrath John
- McKay Joseph
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- McLeish Bethan
- McPherson Duncan
- Meara John G.
- Meead Adullah
- Mehraj Asif
- Meilak Joseph
- Meleiro Hugo
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- Meneghini Simona
- Mengesha Mengistu G.
- Menna Maria Paola
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- Modabber Ali
- Modolo Maria Marta
- Mohamed Ahmed Mohamed Ibrahim
- Mohamed Guleed
- Mohamed Mazin
- Mohamedahmed Ali Yasen Y.
- Mohammed Alhassan Datti
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- Mostafa Badr
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- Musadaq Muhammad
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- Myrelid Par
- Myriokefalitaki Eva
- MĂ©ndez Patricia Serrano
- Nabil Fatma
- Nachelleh Emmanuel Aadereyir
- Nacion Aeris Jane D.
- Nadi Khaldoun
- Naegele Felix
- Naga Hani
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- Nahm Christopher
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- Naranjo Eddy P. Lincango
- Narayanan Vairavan
- Nardo Bruno
- Narvaez-Rojas Alexis Rafael
- Nassar Mahmoud A.
- Nasser Sara
- Nastos Constantinos
- Natale Joseph
- Nataraja Ramesh
- Nathan Arjun
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- Navarrete-PeĂłn Alberto
- Navarro-Barrios Alvaro
- Nazer Ahmed
- Nazimi Abd Jabar
- Ncogoza Isaie
- Neal-Smith Gregory
- Neary Colm
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- Negussie Abraham
- Nemeth Marcus
- Nenna Antonio
- Nepogodiev Dmitri
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- Nevins Edward J.
- Newman Samuel
- Ngaserin Sabrina
- Nicholson Gary
- Niewiera Marc
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- Nissi Evelyn R.
- Nitschke Christine
- Njokanma Iloba
- Noel Colin
- Nolte Peter
- Noureldin Yasser
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- Novysedlåk René
- Ntalouka Maria P.
- Ntirenganya Faustin
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- Nuhu Ahmed Mohammed
- Nunes Rafael Leite
- Nuñez Jorge
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- O'Connell Robert Michael
- O'Connor Alexander
- O'Dwyer Marliza
- O'Riordan James
- Odai Emeka Danielson
- Odicino Franco
- Ofori Emmanuel Owusu
- Ogu Rosemary
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- Ojo Owolabi
- Okere Oghenekevwe
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- Oktseloglou Vlasios
- Okunade Kehinde
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- Olaogun Julius
- Oliver Isabel Mora
- Olivos Maricarmen
- Olori Samson
- Olson Kristofor A.
- Oludara Mobolaji
- Omar David
- Omar Islam
- Omer Mohammed Eltahier Abdalla
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- Oshodi Yusuf
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- Osman Osama Saeed
- Osterhoff Georg
- Othman Ahmad Faidzal
- Othman Amani Alsayd Abdulsalam
- Othman Rema
- Otify Esraa
- Otokwala Job
- Oung Thida
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- Ozair Ahmad
- Ozkan Omer Faruk
- Ozmen Berk Baris
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- Pachajoa Diana Alejandra Pantoja
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- Page Richard
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- Paraskevopoulos Konstantinos
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- Park James
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- Pascale Marco Maria
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- Patrone Renato
- Pattacini Gianmaria Casoni
- Payne Rachel
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- Petruzzi Gerardo
- Pettigrove K.L.
- Phillips Jonathan
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- Pillerstorff Robert
- Pineda Ana MejĂa
- Pinkney Thomas
- Pinney L.
- Pinotti Enrico
- Pinto Romina
- Piozzi Guglielmo NiccolĂČ
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- Pirozzi Brunella Maria
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- Pirzada Muhammad Taqi
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- Pitcher Meron
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- Power Nicholas
- Prada Carlos
- Pradhan Akhilesh
- Pramesh C.S.
- Prats Milagros Carrasco
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- PrijoviÄ NebojĆĄa
- Prodromidou Anastasia
- Proud David
- Prucher Gian Marco
- Prusty Lydia
- Pu Jingya Jane
- Pucher Philip
- Punjabi Prakash P
- Puri Ajay
- Purich Kieran
- PĂ©rez Beatriz GĂłmez
- PĂ©rez-BertĂłlez Sonia
- Qader Kawthar
- Qin Kirby R.
- Quadri Oladeji
- Quaresima Silvia
- Querney Jill
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- Rabie Mohamed
- Racine Michaël
- Radhakrishnan Ajay
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- Radwan Asmaa
- Ragozzino Roberta
- Rahman Atiqur
- Rahy-MartĂn Aida Cristina
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- Rajendram Rajkumar
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- Raptis Dimitri Aristotle
- Rasheed Aqsa
- Rashid Isbah
- Ratto Carlo
- Rauf Umme Habiba Abdul
- Raurich-Leandro Jordi
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- Ravindra Raevin
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- Reichert Martin
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- Reim Daniel
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- Rezende Ricardo Fernandes
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- Ribeiro JoĂŁo
- Riccetti Camilla
- Richard H.
- Rickard Jennifer
- RincĂłn Natalia Andrea Rivera
- Ripollés-Melchor Javier
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- Rodriguez H. Alejandro
- Rodriguez Magdiel
- Rodriguez-Lopez Mario
- RodrĂguez Lorena Varela
- Rokohl Alexander Christopher
- Roland Christina L
- Rolinger Jens
- Romano Angela
- Romano Maurizio
- Romanzi Andrea
- Romera Jorge Sanz
- Romero Patricia
- Ronellenfitsch Ulrich
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- Rotunno Giuseppe
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- Saaid Rahmah
- Sabbagh Abdulrahman J.
- Sabella Danielle
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- Saman Pradeep I.H.D.
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- Santos-Costa Paulo
- Santoshi John Ashutosh
- Santric Veljko
- Sapienza Paolo
- Saponaro Gianmarco
- Saraceno Federica
- Saracoglu Ayten
- Saracoglu Kemal
- Sari Ramazan
- Sarjanoja Elise
- Sars Carl
- Sasia Diego
- Sasireka Veerasamy
- Satchithanantham Vinojan
- Satoskar Savni
- Sayed A. Emad
- Sayyed Raza
- Scabini Stefano
- Scacchi Andrea
- Scafa Anthony Kevin
- Scaramuzzo Rosa
- Scaravilli Luca
- Scaringi Stefano
- Schache Andrew
- Schiavone Vincenzo
- Schizas Dimitrios
- Schizas Nikolaos
- Schmitt Françoise
- Schmitz-Rixen Thomas
- Schneck Emmanuel
- Schröder Lars
- Schweitzer Donald
- Scifo Amedeo
- Scopelliti Michele
- Scott Erin
- Seah Kt Matthew
- Sebai Amine
- Seeliger Barbara
- Seenivasagam Rajkumar Kottayasamy
- Segalini Edoardo
- Segaren Neil
- Segaren Nicholas
- Seglenieks Richard
- Segura-Sampedro Juan José
- Seguya Amina
- Seidu Anwar Sadat
- Seiwerth Ingmar
- SekuliÄ Aleksandar
- Semple Abigail
- Sen Comert
- Senanayake Kithsiri Janakantha
- Senent-Boza Ana
- Seneviratne Sanjeewa
- Senni Carlotta
- Sensi Bruno
- Seraj Shaikh Sanjid
- Serban Andreea-Madalina
- Serenari Matteo
- Serra Margherita
- Serra Marta Lopes
- Seshadri Ramakrishnan Ayloor
- Sethi Aman
- Seyfried Steffen
- Seyi-Olajide Justina
- SeÄan Tomislav
- Sgarzani Rossella
- Shaban Naseebah
- Shaddad Ebrahim
- Shaerf Daniel
- Shah Faaiz Ali
- Shah Hemina
- Shah Jaffer
- Shah Karishma
- Shah Pritik A
- Shah Vinay
- Shaikh Shafaque
- Shalaby Mostafa
- Shalhoub Joseph
- Shamim Shahzad
- Sharma Naveen
- Sharma Neil
- Sharma Rahul Deo
- Sharma Shilpa
- Sharpin Claire
- Sheen Jonathon
- Shehata Sherif
- Shehta Ahmed
- Sheik Shahila
- Sheikh Eman
- Shekleton Florence
- Shelat Vishal
- Shelmerdine Lauren
- Sherif Ahmed Elshawadfy
- Shiban Ehab
- Shiota Masaki
- Shirazi Ahmed
- Shiwani Haaris
- Shmukler Daniel
- Shokor Muntaser Abu
- Sholadoye Tunde T.
- Shoukrie Shoukrie I. M.
- Shrestha Rashmit
- Siboe Mark
- Sica Giuseppe
- Siddig Esra
- Siddiqui M. Tayyab
- Sidiropoulos Theodoros
- Sievers Denise
- Sigamoney Kohila
- Silvestri Vania
- Simoes Joana
- Simon Natalie
- Simoncini Tommaso
- SimÔes Joana Filipa Ferreira
- Singer Georg
- Singh Abhinav
- Singh Baljit
- Singh Kathryn
- Singh Rajdeep
- Singh Tanveer
- Sinnerton Robert
- Siragusa Leandro
- Sivaprakasam Rajesh
- Skipworth Richard Je
- Slavchev Mihail
- Sleem Adham
- Smati Ismail
- Smelt Jeremy
- Smith A.
- Smolle-Juettner Freyja-Maria
- Sodhai Vivek
- Sofi Khalid
- Sohrabi Catrin
- Soibiharry Adaiah
- Sokolov Manol
- Solaini Leonardo
- Sole Oriol Martin
- Sole-Sedeno Josep M.
- Soljic Martina
- Solli Piergiorgio
- Soon Wai Cheong
- Sorbi Flavia
- Sotiropoulou Maria
- Sotudeh Mohadeseh
- Souadka Amine
- Soucheiron Maria Coronas
- Soytas Mustafa
- Sozzi Giulio
- Sparavigna Marco
- Spartalis Michael
- Spellar Kayleigh
- Spiers Harry V. M.
- Spina Alfio
- Spriano Giuseppe
- Squiers John
- Stabler Robert
- Stamatakis Emmanouil
- Stamatis Konstantinos
- Starr Nichole
- Stather Philip
- Stevens Sean
- Stevenson Andrew
- Stewart Grant D.
- Stijns Jasper
- Stogowski Piotr Tomasz
- Stoleriu Mircea Gabriel
- Stoyanov Vladislav
- Street John
- Strotmann Johanna Josefine
- Stroumpoulis Konstantinos
- Su Yu-Xiong
- Suarez Sara Busto
- Subramani Yamini
- Subramaniam Sentilnathan
- Sue-Chue-Lam Colin
- Suer Muhammed Salih
- Sulaiman Bilal
- Sultania Mahesh
- Sundarraju Shalini
- Sungurtekin Hulya
- Suresh Sreelakshmi
- Surya Ilham Utama
- Swed Sarya
- Syllaios Athanasios
- Symeonidis Dimitrios
- SzabĂłmihĂĄlyovĂĄ KatarĂna
- Szakmany Tamas
- Szatmary Peter
- Sztipits TamĂĄs
- Szyluk Karol
- SĂĄ-Marta Eduarda
- Sånchez Alberto Cabañero
- SĂĄnchez Rosa
- Sånchez-Guillén Luis
- SĂŒleyman Marlen
- Tadic Boris
- Taha Anas
- Taha-Mehlitz Stephanie
- Tailor Bhavesh
- Taj Eldeen Samaher Taj Eldeen Hassan
- Takeda Flavio Roberto
- Takkenberg Marijn
- Talat Nabila
- Tallon-Aguilar Luis
- Talwar Rishi
- Tamayo Beatriz Villota
- Tamburello Sara
- Tamini NicolĂČ
- Tammo Ămer
- Tamoos Khalil
- Tampaki Ekaterini Christina
- Tampakis Athanasios
- Tan Chih Ying
- Tan Shawn Jia Hwang
- Tanal Mert
- Tanas Yousef
- Tang Alethea
- Tang Yita
- Tani Sobhana Iftekhar
- Tantraworasin Apichat
- Tantri Aida Rosita
- Tapia-Herrero Ana-MarĂa
- Tarek Ahmed
- Tariq Aiman
- Tarle Marko
- Tarsitano Achille
- Tartaglia Dario
- Tartaglia Nicola
- Tashkandi Wail
- Taskiran Cagatay
- Tatar Cihad
- Tatsis Dimitris
- Tawalbeh Ra'Fat
- Tawiah Augustine
- Tebha Sameer
- Techapongsatorn Suphakarn
- Teixeira Pedro
- Tejero-Pintor Francisco J.
- Tellez Karla Susana Martin
- Tellez Luis Garcia-Sancho
- Thaha Mohamed Adhnan
- Thakar Sumit
- Thaw May Htoo
- Theivendran Kanthan
- Thekkinkattil Dinesh
- Theochari Nikoletta
- Theodoropoulos George
- Theophilidou Elena
- Thereska Dariel
- Thiruchandran Gajendiran
- Thomakos Nikolaos
- Thomas Bradley
- Thomas Jerin Jose
- Thuduvage Vasanthika
- Thumbadoo Ruben
- Tian Sarah
- Tidjane Anisse
- Tirloni Luca
- Toia Francesca
- Tokidis Evripidis
- Tokocin Merve
- Tolani Musliu Adetola
- Toma Elena Adelina
- Tomasicchio Giovanni
- Tomlinson James
- Tonini Valeria
- Torre Beatrice
- Torregrosa Cristina
- Torun Bahar Canbay
- Tottman R.
- Tousidonis Manuel
- Trabulsi Nora
- Tranca Sebastian
- Trebol Jacobo
- Trejo-Avila Mario
- Triantafyllou Alexandra
- Triantafyllou Tania
- Trifunovski Aleksandar
- Tripathi Manjul
- Tripathi Prashant
- Tripathy Sujit
- Trivik-Barrientos Felipe
- Trostchansky Ivan
- Trulson Alexander
- Trungu Sokol
- Truss Adam
- Tsakiridis Ioannis
- Tsakiridis Nikolaos
- Tsiantoula Paraskevi
- Tsironis Dimitrios
- Tsolakidis Alexandros
- Tsoulfas Georgios
- Tucker Olga
- Tuech Jean Jacques
- Turan Alparslan
- Turi Stefano
- Turna Akif
- Turrado-Rodriguez Victor
- Turri Giulia
- Tutino Roberta
- Tuyishime Eugene
- Tzelves Lazaros
- Tzima Ioanna
- Tzimas George
- Ubiali Paolo
- Ubom Akaninyene Eseme
- Ugwu Aloy Okechukwu
- Ugwu Ebere
- Ugwu Ifeanyichukwu
- Ul Huda Maria Noor
- Ulas Ali Bilal
- Uldry Emilie
- Ulgur Hanife Seyda
- Ulkucu Attila
- Ulman Elif Akbas
- Ulman Hilmican
- UlutaĆ Mehmet EĆref
- Underwood Kirk
- Unsworth Richard
- Uprak Tevfik Kivilcim
- Urriza Pablo Vallés
- Usman Muhammad
- Usman Mustapha Ibrahim
- Vaassen Lauretta
- Vaccara Vincenzo La
- Vagena Xanthoula
- Vagge Aldo
- Vailas Michail
- Valadez Andrea Estefania Cueto
- Valadez Tania Abigail Cueto
- Valanci Sofia
- Valdespino Cristina Puentes
- Valeanu Liana
- Valioulis Ioannis
- Valladares Sergio ChĂĄvez
- Vallve-Bernal Marc
- Van Acker Jill
- Van Den Eynde Jef
- Van Goor Harry
- Van Vliet Helen
- Van Wyk Naomi Natasha
- Vanni Camilla
- Vas Aurelia
- Vasarhelyi Edward
- Vaschetti Roberto
- Vassiliu Panteleimon
- Vatansever Dogan
- Vatish Jamie
- Vaughan-Shaw Peter G.
- Vaysburg Dennis
- Veglia Antonella
- Velten Markus
- VelĂĄzquez Maria Jose Martinez
- Venkatappa Sunil Kumar
- Venketeswaran Meenakshi
- Venskutonis Donatas
- Verbic Milena Senica
- Verdi Daunia
- Vergara-Fernandez Omar
- Verhoeff Kevin
- Veroux Massimiliano
- Verras Georgios-Ioannis
- Verre Luigi
- Vida Lucian
- Vidya Raghavan
- Viglietta Edoardo
- Vijay Vardhini
- Vijgen Guy
- VilarĂł Blanca Capdevila
- Villanueva Julio
- Vilz Tim O.
- Vincent Elizabeth
- Vinci Danilo
- Viola Simona
- Violante Tommaso
- Vishnoi Jeewan Ram
- Vissapragada Ravi
- Vivancos Laura Guillamon
- Vives Josep Maria Muñoz
- Vizzielli Giuseppe
- Vohra Lubna
- Vokshi Ismail
- Vosinakis Christos
- Våsquez Javier Alberto Gutiérrez
- VĂĄzquez Gil
- VĂĄzquez Irene Ortega
- VÇcÇraĆu Andrei Bogdan
- Wade Ryckie
- Wafi Omar
- Wagner Gabriela
- Wallis Christopher
- Wanjara Samuel
- Waqar Shahzad Hussain
- Warden Claire
- Warner Christian
- Wasim D.
- Wason Shaun
- Wasserman Isaac
- Watcyn-Jones Tom
- Waterson Ben
- Watson David
- Watson Matthew
- Weber Clemens
- Wheatstone P.
- Wheeler James
- Wheldon Luke
- White Michelle
- White Stuart
- White William
- Wickramasinghe Dakshitha
- Widmer Lukas Werner
- Wiedemann Dominik
- Wiesinger Clemens Georg
- Wijekoon Naveen
- Wijenayake Wasantha
- Wijeyaratne Manuk
- Wijeysundera Duminda
- Wiles Matthew
- Wilkin Richard
- Wilkins Alex
- Wilkins James
- William Tinka George
- Williams Omolara Modupe
- Williams Shekinah
- Windsor John
- Winnand Philipp
- Wittmann Maria
- Wolde Amanuel
- Wolfenden John W. D.
- Wong Benjamin Ngie Xiong
- Wong Enoch
- Wong Evan G.
- Wong George Kwok Chu
- Wong Ho Ying Flora
- Wong Kai Yuen
- Wormald Justin
- Wright Deborah
- Wright Joshua
- Wu Fiona
- Wurm Markus
- Xenaki Sofia
- Yadev Ip
- Yahaya Ahmad Shuib
- Yakubu Mustapha
- Yang Wah
- Yanik Ăzge
- Yanowsky-Reyes Guillermo
- Yassin Abubaker
- Yates Elizabeth
- Yebes Alvaro
- Yenli Edwin Mwintiereh Ta-Ang
- Yeoh Tien
- Yeung Justin
- Yiallourou Anneza
- Yigit Banu
- Yildirim Asif
- Yim Guang
- Yiu Andrew
- Yonekura Hiroshi
- Yotsov Tsanko
- Younis Muhammad Umar
- Yunus Alif
- Yusefi Hossein
- Zabaleta Jon
- Zabkiewicz Catheriner
- Zaccaria Giulia
- Zacharia Bincy
- Zafar Syed Nabeel
- Zago Mauro
- Zaheen Zakia
- Zahid Zahra
- Zaimis Tilemachos
- Zakaria Andee Dzulkarnaen
- Zambon Martina
- Zamora Lindsey
- Zampogna Biagio
- Zancana Giuseppa
- Zani Augusto
- Zanin Luca
- Zanini Nicola
- Zapardiel Ignacio
- Zapata Carlos Shiraishi
- Zarif Pierre
- ZarĂĄnd Attila
- Zehnder Philipp
- Zenger Serkan
- Zenha HorĂĄcio
- Zhu Michael Z. L.
- Ziemann Sebastian
- Zimak Danijela Mrazovac
- Zimak Zoran
- Zivkovic Dragana
- Zizzo Maurizio
- Zucker Benjamin
- Zwain Yasir
- Zyskowski Michael
- Ăvila Clara Castro
- ĂlgĂ„ Andreas
- Ăakici Mehmet Ăaǧlar
- Ăelik Enes
- Ăelik Meryem Nur
- Ăzçay Necdet
- Ćevik HĂŒsnĂŒ
- Ć antak Goran
- Ć imko KristiĂĄn
- ĆœateckĂœ Jan
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2023
- Field of study
Abstract
Background
Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres.
Methods
This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and lowâmiddle-income countries.
Results
In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of âsingle-useâ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for lowâmiddle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia.
Conclusion
This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both highâ and lowâmiddleâincome countries
COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study
- Author
- Abdukahil Sheryl Ann
- Abdukahil Sheryl,
- Abe Ryuzo
- Abel Laurent
- Abreu Julia Rodriguez
- Abreu Julia,
- Absil Lara
- Acker Andrew
- Adachi Shingo
- Adam Elisabeth
- AdriĂŁo Diana
- Ainscough Kate
- Akimoto Takako
- Al Qasim Eman
- Al-Dabbous Tala
- Al-Fares Abdulrahman
- Alalqam Razi
- Alex Beatrice
- Alexandre KĂ©vin
- Alfoudri Huda
- Alidjnou Kazali Enagnon
- Alidjnou Kazali,
- Aliudin Jeffrey
- Allavena Clotilde
- Allou Nathalie
- Alves JoĂŁo
- Alves Rita
- Amaral Maria
- Ammerlaan Heidi
- Ampaw Phoebe
- Andini Roberto
- Andrejak Claire
- Angheben Andrea
- ANGOULVANT François
- Ansart SĂ©verine
- Antonelli Massimo
- Arabi Yaseen
- Aragao Irene
- Arcadipane Antonio
- Arenz Lukas
- Arlet Jean-BenoĂźt
- Arnold-Day Christel
- Arora Lovkesh
- Artaud-Macari Elise
- Asensio Angel
- Assie Jean Baptiste
- Assie Jean,
- Atique Anika
- Auchabie Johann
- Aumaitre Hugues
- Azemar LaurĂšne
- Azoulay CĂ©cile
- Bach Benjamin
- Bachelet Delphine
- Baillie J. Kenneth,
- Bak Erica
- Bakakos Agamemnon
- Banisadr Firouzé
- Barbalho Renata
- Barclay Wendy,
- Barnikel Michaela
- Barrelet Audrey
- Barrigoto Cleide
- Basmaci Romain
- Bassi Gianluigi Li
- Bassi Gianluigi,
- Bedossa Alexandra
- Behilill Sylvie
- Bekken Gry Kloumann
- Bekken Gry,
- Beljantsev Aleksandr
- Bellemare David
- Beltrame Anna
- Beluze Marine
- Benech Nicolas
- Benkerrou Dehbia
- Bennett Suzanne
- Bento LuĂs
- Berdal Jan-Erik
- Bergeaud Delphine
- Bertolino Lorenzo
- Bessis Simon
- Bevilcaqua Sybille
- Bhavsar Krishna
- Bissuel François
- Biston Patrick
- Bitker Laurent
- Blanco-Schweizer Pablo
- Blot Mathieu
- Boccia Filomena
- Bogaert Debby
- Bompart François
- Booth Gareth
- Borges Diogo
- Borie Raphaël
- Bos Jeannet
- Bosse Hans Martin
- Bosse Hans,
- Botelho-Nevers Elisabeth
- Bouadma Lila
- Bouchaud Olivier
- Bouchez Sabelline
- Bouhmani Dounia
- Bouhour Damien
- Bouiller KĂ©vin
- Bouillet Laurence
- Bouisse Camille
- Boureau Anne-Sophie
- Bouscambert Maude
- Bouziotis Jason
- Boxma Bianca
- Boyer-Besseyre Marielle
- Boylan Maria
- Braga Cynthia
- Brandenburger Timo
- Brazzi Luca
- Breen Dorothy
- Breen Patrick
- Brickell Kathy
- Brozzi Nicolas
- Buchtele Nina
- Buesaquillo Christian
- Bugaeva Polina
- Buisson Marielle
- Burhan Erlina
- Bustos Ingrid,
- Butnaru Denis
- Cabie André
- Cabral Susana
- Caceres Eder
- Callahan Mia
- Calligy Kate
- Calvache Jose Andres
- Calvache Jose,
- Campana Valentine
- Campbell Paul
- CamÔes João
- Canepa Cecilia
- Cantero Mireia
- Caraux-Paz Pauline
- Cardoso Filipa
- Cardoso Filipe
- Cardoso Sofia
- Carelli Simone
- Carlier Nicolas
- Carney Gayle
- Carpenter Chloe
- Carret Marie-Christine
- Carrier François Martin
- Carrier François,
- Carson Gail
- Casanova Maire-Laure
- CascĂŁo Mariana
- Casimiro José
- Cassandra Bailey
- Castanheira Nidyanara
- Castañeda Silvia
- Castor-Alexandre Guylaine
- CastrillĂłn Henry
- Castro Ivo
- Catarino Ana
- Catherine François-Xavier
- Cavalin Roberta
- Cavalli Giulio Giovanni
- Cavalli Giulio,
- Cavayas Alexandros
- Ceccato Adrian
- Cervantes-Gonzalez Minerva
- Chair Anissa
- Chakveatze Catherine
- Chan Adrienne
- Chand Meera
- Chas Julie
- Chassin Camille
- Chen Anjellica
- Chen Yih-Sharng
- Cheng Matthew Pellan
- Cheng Matthew,
- Cheret Antoine
- Chiarabini Thibault
- Chica Julian
- Chirouze Catherine
- Chiumello Davide
- Cho Hwa Jin
- Cho Hwa,
- Cho Sung Min
- Cho Sung,
- Choez Xavier SĂĄnchez
- Choez Xavier,
- Choileain Orna Ni
- Choileain Orna,
- Cholley Bernard
- Cidade Jose Pedro
- Cidade Jose,
- Citarella Barbara Wanjiru
- Citarella Barbara,
- Ciullo Anna
- Clarke Jennifer
- Clohisey Sara
- Codan Cassidy
- Cody Caitriona
- Coelho Alexandra
- Colin Gwenhaël
- Collins Michael
- Colombo Sebastiano Maria
- Colombo Sebastiano,
- Combs Pamela
- Connelly J.,
- Connor Marie
- Conrad Anne
- Contreras SofĂa
- Cooke Graham,
- Copland Mary
- Cordel Hugues
- Corley Amanda
- Cormican Sarah
- Cornelis Sabine
- Corpuz Arianne Joy
- Corpuz Arianne,
- Corvaisier Grégory
- Couffignal Camille
- Couffin-Cadiergues Sandrine
- Courtois Roxane
- Croonen Sabine
- Crowl Gloria
- Crump Jonathan
- Cruz Claudina
- Csete Marc
- Cucino Alberto
- Cullen Caroline
- Cummings Matthew
- Curley Gerard
- Curlier Elodie
- Curto Elena Gallego
- Curto Elena,
- Custodio Paula
- CĂĄrcel Sheila
- Da Silva Filipe Ana
- Da Silveira Charlene
- Dabaliz Al-Awwab
- Dagens Andrew,
- Dalton Heidi
- Dalton Jo
- Daneman Nick
- Dankwa Emmanuelle,
- Dantas Jorge
- De AraĂșjo Mariz Carolline
- De Brito Carlos Alexandre Antunes
- De Brito Carlos,
- De Castro Nathalie
- De Mendoza Diego
- De Oliveira França Rafael Freitas
- De Oliveira França Rafael,
- De Rosa Rosanna
- De Silva Thushan
- De Vries Peter
- Dean David
- Debray Marie-Pierre
- Dechert William
- Deconninck Lauren
- Decours Romain
- Delacroix Isabelle
- Delavigne Karen
- Deligiannis Ionna
- Dellâamore Andrea
- Delobel Pierre
- Demonchy Elisa
- Denis Emmanuelle
- Deplanque Dominique
- Depuydt Pieter
- Desai Mehul
- Descamps Diane
- Desvallée Mathilde
- Devouge Eglantine Ferrand
- Devouge Eglantine,
- Dewayanti Santi Rahayu
- Dewayanti Santi,
- Diallo Alpha
- Diamantis Sylvain
- Dias André
- Diaz Juan Jose Diaz
- Diaz Juan,
- DIAZ Rodrigo
- Didier KĂ©vin
- Diehl Jean-Luc
- Dieperink Wim
- Dimet JĂ©rĂŽme
- Dinot Vincent
- Diouf Alphonsine
- Dishon Yael
- Djossou FĂ©lix
- Docherty Annemarie,
- Dominguez Carmen Infante
- Dominguez Carmen,
- Dong Andy
- Donnelly Christl,
- Donnelly Maria
- Donohue Chloe
- Dorival CĂ©line
- Douglas James Joshua
- Douglas James,
- Douma Renee
- Dournon Nathalie
- Downer Triona
- Downing Mark
- Drake Tom
- Dubee Vincent
- DUBOS François
- Ducancelle Alexandra
- Dudman Susanne
- Dunning Jake
- Duranti Silvia
- Durham Lucian
- Dussol Bertrand
- Duval Xavier
- Dyrhol-Riise Anne Margarita
- Dyrhol-Riise Anne,
- Dâaragon FrĂ©dĂ©rick
- DâOrleans Charles Crepy
- Dâorleans Charles,
- DâOrtenzio Eric
- Eid Charbel Maroun
- Eid Charbel,
- Eira Carla
- Elapavaluru Subbarao
- Elharrar Brigitte
- Elkheir Natalie
- Ellerbroek Jacobien
- Ellis Rachael
- Eloy Philippine
- Elshazly Tarek
- Enderle Isabelle
- Engelmann Ilka
- Enouf Vincent
- Epaulard Olivier
- Esperatti Mariano
- Esperou HĂ©lĂšne
- Esposito-Farese Marina
- EstevĂŁo JoĂŁo
- Etienne Manuel
- Ettalhaoui Nadia
- Everding Anna Greti
- Everding Anna,
- Evers Mirjam
- Fabre Isabelle
- Faheem Amna
- Fahy Arabella
- Fairfield Cameron,
- Faria Pedro
- Farshait Nataly
- Fatoni Arie Zainul
- Fatoni Arie,
- Faure Karine
- Fayed Mohamed
- Feely Niamh
- Fernandes Jorge
- Fernandes MarĂlia
- Fernandes Susana
- Ferraz MĂĄrio
- Ferreira Benigno
- Ferrer-Roca Ricard
- FerrĂŁo Joana
- Figueiredo-Mello Claudia
- Flateau Clara
- Fletcher Tom
- Florio Letizia Lucia
- Florio Letizia,
- Foley Claire
- Fomin Victor
- Fonseca Claudio Duarte
- Fonseca Claudio,
- Fonseca Tatiana
- Fontela Patricia
- Forsyth Simon
- Foti Giuseppe
- Fourn Erwan
- Fowler Rob
- Franch-Llasat Diego
- Fraser Christophe
- Fraser John
- Freire Marcela Vieira
- Freire Marcela,
- Friedrich Caren
- Fry Stéphane
- Fuentes Nora
- Fukuda Masahiro
- Gaborieau Valérie
- Gachet BenoĂźt
- Gaci Rostane
- Gagliardi Massimo
- Gagnard Jean-Charles
- Gagneux-Brunon Amandine
- GaiĂŁo SĂ©rgio
- Gallagher Phil
- Gamble Carrol
- Garan Arthur
- Garcia Rebekha
- Garcia-Gallo Esteban
- GarcĂa Ruth NoemĂ Jorge
- GarcĂa Ruth,
- Garot Denis
- Garrait Valérie
- Gault Nathalie
- Gavin Aisling
- Gaymard Alexandre
- Gebauer Johannes
- Germano Nuno
- Ghosn Jade
- Giani Marco
- Giaquinto Carlo
- Gibson Jess
- Gigante Tristan
- Gilg Morgane
- Giordano Guillermo
- Girvan Michelle
- Gissot Valérie
- Giwangkancana Gezy
- Glikman Daniel
- Glybochko Petr
- Gnall Eric
- Goco Geraldine
- Goehringer François
- Goepel Siri
- Goffard Jean-Christophe
- Golob Jonathan
- Gorenne Isabelle
- Goujard CĂ©cile
- Goulenok Tiphaine
- Grable Margarite
- Grandin Edward Wilson
- Grandin Edward,
- Granier Pascal
- Grasselli Giacomo
- Green Christopher,
- Greenhalf William
- Greffe SegolĂšne
- Grieco Domenico Luca
- Grieco Domenico,
- Griffee Matthew
- Griffiths Fiona
- Grigoras Ioana
- Groenendijk Albert
- Gruner Heidi
- Gu Yusing
- Guedj Jérémie
- Guellec Dewi
- Guerguerian Anne-Marie
- Guerreiro Daniela
- Guery Romain
- Guillaumot Anne
- Guilleminault Laurent
- Guimard Thomas
- GĂłmez-Junyent Joan
- Haber Daniel
- Hakak Sheeba
- Hall Matthew
- Halpin Sophie
- Hamer Ansley
- Hamidfar Rebecca
- Hammond Terese
- Hardwick Hayley
- Harley Kristen
- Harrison Ewen,
- Harrison Janet
- Hays Leanne
- Heerman Jan
- Heggelund Lars
- Hendry Ross
- Hennessy Martina
- Henriquez-Trujillo Aquiles
- Hentzien Maxime
- Hernandez-Montfort Jaime
- Herreros Jose Miguel Cisneros
- Herreros Jose,
- Hidayah Astarini
- Higgins Dawn
- Higgins Eibhilin
- Hinton Samuel
- HipĂłlito-Reis Ana
- Hiraiwa Hiroaki
- Hiscox Julian,
- Ho Antonia Ying Wai
- Ho Antonia,
- Hoctin Alexandre
- Hoffmann Isabelle
- Hoiting Oscar
- Holt Rebecca
- Holten Aleksander Rygh
- Holten Aleksander,
- Holter Jan Cato
- Holter Jan,
- Horby Peter
- Horcajada Juan Pablo
- Horcajada Juan,
- Hoshino Koji
- Hoshino Kota
- Hough Catherine,
- Hssain Ali Ait
- Hssain Ali,
- Hsu Jimmy Ming-Yang
- Hulot Jean-SĂ©bastien
- Humaid Felwa Bin
- Humaid Felwa,
- Ijaz Samreen
- Illes Hajnal-Gabriela
- InĂĄcio Hugo
- Iosifidis Elias
- Irvine Lacey
- Isgett Sarah
- Isidoro Tiago
- Isnard Margaux
- Itai Junji
- Ivulich Daniel
- Jaafoura Salma
- Jabot Julien
- Jackson Clare
- Jamieson Nina
- Jaureguiberry Stéphane
- Javidfar Jeffrey
- Jean-BenoĂźt Zabbe
- Jego Florence
- Jenum Synne
- Jimenez Juan Fernado Masa
- Jimenez Juan,
- Johal Simreen Kaur
- Johal Simreen,
- Joseph CĂ©dric
- Joseph Mark
- Jouvet Philippe
- Jung Hanna
- Kafif Ouifiya
- Kaguelidou Florentia
- Kali Sabina
- Kalomoiri Smaragdi
- Kandamby Darshana Hewa
- Kandamby Darshana,
- Kandel Chris
- Kant Ravi
- Kartsonaki Christiana
- Kasugai Daisuke
- Katz Kevin
- Keating Sean
- Kelly Andrea
- Kelly Sadie
- Kennedy Lisa
- Kennon Kalynn
- Kerroumi Younes
- Kestelyn Evelyne
- Khalid Imrana
- Khalil Antoine
- Khan Coralie
- Khan Irfan
- Kho Michelle,
- Khoo Saye
- Kida Yuri
- Kiiza Peter
- Kildal Anders Benjamin
- Kildal Anders,
- Kimmoun Antoine
- Kindgen-Milles Detlef
- Kitamura Nobuya
- Klenerman Paul
- Knight Stephen
- Kobbe Robin
- Korten Volkan
- Kosgei Caroline
- Krawczyk Karolina
- KUMAR Deepali
- Kurtzman Ethan
- Kutsogiannis Demetrios
- Kyriakoulis Konstantinos
- LACHATRE Marie
- Lacoste Marie
- Laffey John,
- Lagrange Marie
- Laine Fabrice
- Lambert Marc
- Lamontagne François
- Langelot-Richard Marie
- Lantang Eka Yudha
- Lantang Eka,
- Lanza Marina
- Laouénan Cédric
- Laribi Samira
- Lariviere Delphine
- Launay Odile
- Lavie-Badie Yoan
- Law Andrew
- Le Bihan Clément
- Le Bris Cyril
- Le Coustumier Eve
- Le Falher Georges
- Le Gac Sylvie
- Le Hingrat Quentin
- Le Maréchal Marion
- Le Mestre Soizic
- Le Moing Vincent
- Le Nagard Hervé
- Le Turnier Paul
- Le Van Tan
- Le Minh
- Leal Ema
- Lee James
- Lee Su Hwan
- Lee Su,
- Lee Todd
- Leeming Gary
- Lefebvre Bénédicte
- Lefebvre Laurent
- Lefevre Benjamin
- Lellouche François
- Lemaignen Adrien
- Lemee VĂ©ronique
- Lemmink Gretchen
- Leone Michela
- Lepiller Quentin
- Lescure François-Xavier
- Lesens Olivier
- Lesouhaitier Mathieu
- Levy Bruno
- Levy Yves
- Levy-Marchal Claire
- LeĂłn Rafael
- Liang Janet
- Lim Wei Shen
- Lim Wei,
- Lina Bruno
- Lind Andreas
- Lingas Guillaume
- Lion-Daolio Sylvie
- Liu Keibun
- Loforte Antonio
- Lolong Navy
- Lopes Diogo
- Lopez-Colon Dalia
- Lordemann Anja Grosse
- Lordemann Anja,
- Loubet Paul
- Lucet Jean Christophe
- Lucet Jean,
- Luna Carlos,
- Lungu Olguta
- Luong Liem
- Luton Dominique
- Lyons Ruth
- LâHer Erwan
- Maasikas Olavi
- Macdonald Sarah
- Machado MoĂŻse
- Macheda Gabrielle
- Madhok Jai
- Mahieu Rafael
- Mahy Sophie
- Maier Lars Siegfrid
- Maier Lars,
- Maillet MylĂšne
- Maitre Thomas
- Malaque Ana
- Maldonado Hugo Miranda
- Maldonado Hugo,
- Malfertheiner Maximilian
- Malik Nadia
- Maltez Fernando
- Malvy Denis
- MAMBERT Marina
- Manda Victoria
- Mandei Jose,
- Mangoni Emanuele Durante
- Mangoni Emanuele,
- Manning Edmund
- Manuel Aldric
- Marino FlĂĄvio
- Marques Ana
- Marquis Catherine
- Marsh Brian
- Marsh Laura
- Marshall John
- Martelli Celina Turchi
- Martelli Celina,
- Martin Dori-Ann
- Martin Emily
- Martin-Blondel Guillaume
- Martin-Loeches Ignacio
- Martin-Quiros Alejandro
- Martinot Martin
- Martins Ana
- Martins JoĂŁo
- Martucci Gennaro
- Marwali Eva Miranda
- Marwali Eva,
- Maslove David
- Mason Sabina
- Matan Moshe
- Mathieu Daniel
- Mattei Mathieu
- Matulevics Romans
- Maulin Laurence
- Mc Evoy Natalie
- Mccarthy Aine
- Mccloskey Colin
- Mcconnochie Rachael
- Mcdermott Sherry
- McDonald Sarah
- Mcelwee Samuel
- Mcevoy Natalie
- McGeer Allison
- Mcguinness Niki
- Mclean Kenneth,
- Mcnicholas Bairbre
- Meaney Edel
- Mear-Passard CĂ©cile
- Mechlin Maggie
- Mele Ferruccio
- Menon Kusum
- Mentré France
- Mentzer Alexander,
- Mercier Noémie
- Merckx Antoine
- Mergler Blake
- Merson Laura
- Mesquita AntĂłnio
- Meybeck AgnĂšs
- Meynert Alison,
- Meyssonnier Vanina
- Meziane Amina
- Mezidi Medhi
- Michelanglei CĂ©line
- MihnovitĆĄ Vladislav
- Mohammed Nassima Si
- Mohammed Nassima,
- Moin Asma
- Molina David
- Molinos Elena
- Mone Mary
- Monteiro Agostinho
- Montes Claudia
- Montrucchio Giorgia
- Moore Sarah
- Moore Shona,
- Morales-Cely Lina
- Morlaes Louis Gerbaud
- Morlaes Louis,
- Moro Lucia
- Motos Ana
- Mouquet Hugo
- Moyet Julien
- Mullaert Jimmy
- Munblit Daniel
- Murphy Derek
- Murris MarlĂšne
- Myrodia Dimitra Melia
- Myrodia Dimitra,
- MĂŒller Fredrik
- MĂŒller Karl Erik
- MĂŒller Karl,
- Neant NadĂšge
- Neb Holger
- Nekliudov Nikita,
- Neto Raul
- Neumann Emily
- Neves Bernardo
- Ng Pauline Yeung
- Ng Pauline,
- Ng Wing Yiu
- Ng Wing,
- Nichol Alistair
- Nonas Stephanie
- Noret Marion
- Norman Lisa
- Notari Alessandra
- Noursadeghi Mahdad
- Nowicka Karolina
- Nseir Saad
- Nunez Jose,
- Nuñez Maria Angelica Rivera
- Nuñez Maria,
- Nyamankolly Elsa
- NâGuyen Yohan
- Occhipinti Giovanna
- Ogston Tawnya
- Ogura Takayuki
- Oh Tak-Hyuk
- Ohshimo Shinichiro
- Oinam Budha Charan Singh
- Oinam Budha,
- Oliveira Ana Pinho
- Oliveira Ana,
- Oliveira JoĂŁo
- Olliaro Piero
- Ong David,
- Oosthuyzen Wilna
- Openshaw Peter,
- Orozco-Chamorro Claudia Milena
- Orozco-Chamorro Claudia,
- Orquera Andrés
- Osatnik Javier
- Ouamara Nadia
- Ouissa Rachida
- Owyang Clark
- Oziol Eric
- Oâdonnell Max
- Oâhearn Katie
- Oâneil Conar
- Pagadoy MaĂŻder
- Pages Justine
- Palacios Mario
- Palmarini Massimo
- Panarello Giovanna
- Panda Prasan Kumar
- Panda Prasan,
- Panigada Mauro
- Pansu Nathalie
- Papadopoulos Aurélie
- Parra Briseida
- Pasquier Jérémie
- Patauner Fabian
- PatrĂŁo LuĂs
- Paul Christelle
- Paul Mical
- Paulos Jorge
- Paxton William,
- Payen Jean-François
- Pearse India
- Peek Giles,
- Peelman Florent
- Peiffer-Smadja Nathan
- Peigne Vincent
- Pejkovska Mare
- Peltan Ithan,
- Pereira Rui
- Perez Daniel
- Perpoint Thomas
- Perrot Clara Mouton
- Perrot Clara,
- Pesenti Antonio
- PetrouĆĄovĂĄ Lenka
- Petrov-Sanchez Ventzislava
- Peytavin Gilles
- Pharand Scott
- Piagnerelli Michael
- Picard Walter
- Picone Olivier
- Piel-Julian Marie
- Pierobon Carola
- Pimentel Carlos
- Piroth Lionel
- Pius Riinu
- Piva Simone
- Plantier Laurent
- Plotkin Daniel
- Poissy Julien
- Pokorska-Spiewak Maria
- Poli Sergio
- Pollakis Georgios
- Popielska Jolanta
- Postma Douwe,
- Povoa Pedro
- Powis Jeff
- Prapa Sofia
- Prebensen Christian
- Preiser Jean-Charles
- Prestre Vincent
- Price Nicholas
- Prinssen Anton
- Pritchard Mark,
- Proença LĂșcia
- Purcell Gregory
- Puéchal Oriane
- PĂłvoas Diana
- Quesada Luisa
- Quist-Paulsen Else
- Quraishi Mohammed
- Rabaud Christian
- Rafiq Marie
- Ragazzo Gabrielle
- Rainieri Fernando
- Ramakrishnan Nagarajan
- Ramanathan Kollengode
- Rammaert Blandine
- Rapp Christophe
- Rasmin Menaldi
- Rau Cornelius
- Rebaudet Stanislas
- Redl Sarah
- Reeve Brenda
- Rego Caroline Martins
- Rego Caroline,
- Reid Liadain
- Reis Renato
- Remppis Jonathan
- Remy Martine
- Renk Hanna
- Resende Liliana
- Resseguier Anne-Sophie
- Revest Matthieu
- Rewa Oleksa
- Reyes Luis Felipe
- Reyes Luis,
- Ribeiro Ana Freitas
- Ribeiro Ana,
- Richardson David
- Richardson Denise
- Richier Laurent
- Riera Jordi
- Rincon Diego Fernando Bautista
- Rincon Diego,
- Rios Ana LĂșcia
- Rios Ana,
- Rishu Asgar
- Rispal Patrick
- Risso Karine
- Rizer Nicholas
- Roberto André
- Roberts Stephanie
- Robertson David,
- Robineau Olivier
- Roche-Campo Ferran
- Rodari Paola
- Rodeia SimĂŁo
- Roilides Emmanuel
- Rojek Amanda
- Romaru Juliette
- Roncon-Albuquerque Roberto
- Roriz MĂ©lanie
- Rosa-Calatrava Manuel
- Rose Michael
- Rosenberger Dorothea
- Rossanese Andrea
- Rossignol Bénédicte
- Rossignol Patrick
- Roy Carine
- Roze BenoĂźt
- Russell Clark,
- Ryckaert Steffi
- RĂ€tsep Indrek
- Rössler Bernhard
- Saba Isabela
- Sadat Musharaf
- Saidani Nadia
- Salazar Leonardo
- Sales Gabriele
- Sallaberry Stéphane
- Salvator HĂ©lĂšne
- Sanchez Juan Macias
- Sanchez Juan,
- Sanchez Olivier
- Sanchez-Miralles Angel
- Sancho-Shimizu Vanessa
- Sandhu Gyan
- Sandulescu Oana
- Sanharawi Mohammed El
- Sanharawi Mohammed,
- Sant Ceila Maria
- Sant Ceila,
- Santos Marlene
- Santos Marta Leal
- Santos Marta,
- Santos-Olmo Rosario Maria Torres
- Santos-Olmo Rosario,
- Sarfo-Mensah Shirley
- Sarton Benjamine
- Saviciute Egle
- Savvidou Parthena
- Scarsbrook Joshua
- Schermer Tjard
- Scherpereel Arnaud
- Schneider Marion
- Schroll Stephan
- Schwameis Michael
- Scott Janet,
- Scott-Brown James
- Sedillot Nicholas
- Seitz Tamara
- Semaille Caroline
- Semple Malcolm,
- Senneville Eric
- Sequeira Filipa
- Sequeira TĂąnia
- Shadowitz Ellen
- Shamsah Mohammad
- Sharma Pratima
- Shaw Catherine,
- Shaw Victoria
- Shiban Nisreen
- Shime Nobuaki
- Shimizu Hiroaki
- Shimizu Keiki
- Shrapnel Sally
- Shum Hoi Ping
- Shum Hoi,
- Sigfrid Louise
- Silva Catarina
- Silva Maria Joao
- Silva Maria,
- Sin Wai Ching
- Sin Wai,
- Skogen Vegard
- Smith Sue
- Smood Benjamin
- Smyth Michelle
- Snacken Morgane
- So Dominic
- Solis Monserrat
- Solomon Joshua
- Solomon Tom
- Somers Emily
- Sommet AgnĂšs
- Song Myung Jin
- Song Myung,
- Song Rima
- Song Tae
- Sonntagbauer Michael
- Sotomayor Ruth Jimbo
- Sotomayor Ruth,
- Soum Edouard
- Sousa Marta
- Souza-Dantas Vicente
- Sperry Alexandra
- Sriskandan Shiranee
- Staudinger Thomas
- Stecher Stephanie-Susanne
- Stienstra Ymkje
- Stiksrud Birgitte
- Streinu-Cercel Adrian
- Streinu-Cercel Anca
- Strudwick Samantha
- Stuart Ami
- Stuart David
- Suen Jacky,
- Sultana Asfia
- Summers Charlotte
- Svistunov Magdalena SurovcovĂĄ Andrey A.
- Svistunov Magdalena,
- Syrigos Konstantinos
- Sztajnbok Jaques
- Szuldrzynski Konstanty
- Tabrizi Shirin
- Tagherset Lysa
- Talarek Ewa
- Taleb Sara
- Talsma Jelmer
- Tamlihat Younes Ait
- Tamlihat Younes,
- Tanaka Hiroyuki
- Tanaka Taku
- Taniguchi Hayato
- Tardivon Coralie
- Tattevin Pierre
- Taufik M. Azhari,
- Tedder Richard,
- Teixeira JoĂŁo
- Tellier Marie-Capucine
- Terpstra Pleun
- Terrier Olivier
- Terzi Nicolas
- Tessier-Grenier Hubert
- Thibault V.
- Thiberville Simon-Djamel
- Thill BenoĂźt
- Thompson A.,
- Thompson Shaun
- Thomson David
- Thomson Emma,
- Thuy Duong Bich
- Thuy Duong,
- Thwaites Ryan,
- Timashev Peter,
- Timsit Jean-François
- Toki Maria
- Tonby Kristian
- Torres Antoni
- Torres Margarida
- Trieu Huynh Trung
- Trieu Huynh,
- Trioux Théo
- Tromeur CĂ©cile
- Trontzas Ioannis
- Troost Jonathan
- Trouillon Tiffany
- Tual Christelle
- Tubiana Sarah
- Tuite Helen
- Turtle Lance,
- Tutillo Diego Rolando Morocho
- Tutillo Diego,
- Twardowski Pawel
- Téoulé François
- Uchiyama Makoto
- Ullrich Roman
- Uribe Alberto
- Usman Asad
- Uva Maria Sousa
- Uva Maria,
- Val-Flores LuĂs
- Van De Velde Stijn
- Van Den Berge Marcel
- Van Der Feltz Machteld
- Van Der Vekens Nicky
- Van Der Voort Peter
- Van Der Werf Sylvie
- Van Dyk Marlice
- Van Gulik Laura
- Van Hattem Jarne
- Van Lelyveld Steven
- Van Netten Carolien
- Van Vinh Chau Nguyen
- Vanel Noémie
- Vanoverschelde Henk
- Vasconcelos Malte Kohns
- Vasconcelos Malte,
- Vauchy Charline
- Vecham Pavan Kumar
- Vecham Pavan,
- Veislinger Aurélie
- Velazco Jorge
- Ventura Sara
- Verbon Annelies
- Vidal José Ernesto
- Vidal José,
- Vieira CĂ©sar
- Vijayaraghavan Bharath Kumar Tirupakuzhi
- Vijayaraghavan Bharath,
- Villanueva Joy Ann
- Villanueva Joy,
- Villar Judit
- Villeneuve Pierre-Marc
- Villoldo Andrea
- Visseaux Benoit
- Visser Hannah
- Vuorinen Aapeli
- Vuotto Fanny
- Wang Chih-Hsien
- Wei Jia
- Weil Katharina
- Wesselius Sanne
- Wham Murray
- Whelan Bryan
- White Nicole
- Wiedemann Aurélie
- Wille Keith
- Wils Evert-Jan
- Xynogalas Ioannis
- Yacoub Sophie
- Yamazaki Masaki
- Yazdanpanah Yazdan
- Yelnik CĂ©cile
- Yerkovich Stephanie
- Yokoyama Toshiki
- Yonis Hodane
- Young Paul
- Yuliarto Saptadi
- Zabbe Marion
- Zacharowski Kai
- Zahran Maram
- Zambon Maria
- Zanella Alberto
- Zawadka Konrad
- Zayyad Hiba
- Zoufaly Alexander
- Zucman David
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2021
- Field of study
Background:
The ISARIC prospective multinational observational study is the largest cohort of hospitalized patients with COVID-19. We present relationships of age, sex, and nationality to presenting symptoms.
Methods:
International, prospective observational study of 60â109 hospitalized symptomatic patients with laboratory-confirmed COVID-19 recruited from 43 countries between 30 January and 3 August 2020. Logistic regression was performed to evaluate relationships of age and sex to published COVID-19 case definitions and the most commonly reported symptoms.
Results:
âTypicalâ symptoms of fever (69%), cough (68%) and shortness of breath (66%) were the most commonly reported. 92% of patients experienced at least one of these. Prevalence of typical symptoms was greatest in 30- to 60-year-olds (respectively 80, 79, 69%; at least one 95%). They were reported less frequently in children (â€â18 years: 69, 48, 23; 85%), older adults (â„â70 years: 61, 62, 65; 90%), and women (66, 66, 64; 90%; vs. men 71, 70, 67; 93%, each Pâ<â0.001). The most common atypical presentations under 60 years of age were nausea and vomiting and abdominal pain, and over 60 years was confusion. Regression models showed significant differences in symptoms with sex, age and country.
Interpretation:
This international collaboration has allowed us to report reliable symptom data from the largest cohort of patients admitted to hospital with COVID-19. Adults over 60 and children admitted to hospital with COVID-19 are less likely to present with typical symptoms. Nausea and vomiting are common atypical presentations under 30 years. Confusion is a frequent atypical presentation of COVID-19 in adults over 60 years. Women are less likely to experience typical symptoms than men