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Effect of Some Medicinal Plants on the Activity of Some Immunological Factors in Saliva and Serum of Type –?? Diabetics

Author: Al-Jammas Rawdha K.
Al-Mahdawi Ferial A.
Al-Mukhtar Abbas F.
Publication venue: College of Science for Women - University of Baghdad
Publication date: 01/06/2014
Field of study

The study involved 45 male and 45 females of diabetic patients type- ?? aged from 40-69years , and with the same numbers of males and females for control , all the patients and controls were without any periodontal diseases and without any systemic disease. Diabetic patients were divided in to three groups according to the degree of periodontitis , and the inflamed gingiva of all groups of diabetic patients were treated with the dried fruits powder (crude) of medicinal plants Quercus robur , Thuja occidenalis , Terminalia chebula, Anethum graveolens , respectively and mixture. Some immunological and antimicrobial factors (IgA, Lactoferrin , Lysozyme ) , were detected in serum and saliva of diabetic patients and the controls , the results revealed that the level of IgA , Lysozyme in saliva were more than in serum of the control , and this will insure that these factors are considered to be generally protected against bacteria in the oral cavity . Also there was a significant increase at (p?0.001) especially after treatment with the mixture of medicinal plants , so that the mixture of these plants can be considered the best type in the treatment of inflamed gingiva of type –?? diabetic patients

Baghdad Science Journal

Elective Cancer Surgery in COVID-19-Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study.

Author: Aawsaj Y.
Abad Gurumeta A.
Abad-Motos A.
Abate E.
Abatini C.
Abbadessa F.
Abbas A. M.
Abbassi-Ghadi N.
Abbott D.
Abbott T.
Abd Elazeem H. A. S.
Abdalla M.
Abdallah M.
Abdel Al S.
Abdel Jalil R.
Abdeldayem H.
Abdelkader Salama I.
Abdelkarem M. M.
Abdelkarim M.
Abdelmajeed A.
Abdelrahman A.
Abdelrahman S.
Abdelsamed A.
Abdou M.
Abdulkareem A.
Abdulwahed E.
Abdur-Rahman L.
Abel M. K.
Abellan M.
Aboelkassem Ibrahim A.
Abosamak N. E.
Abou Chaar M. K.
Abou-Khalil J.
Abouassi A.
Aboulkassem H.
Abreu Da Silva A.
Abu J.
Abu Za'nouneh F. J.
Abu-Nayla I.
Abubakar A.
Acebes Garcia F.
Achalandabaso Boira M.
Acher A.
Acrich E.
Adamina M.
Adamoli L.
Addae-Boateng E.
Aderombi A.
Adeyeye A.
Adiamah A.
Adishesh M.
Agapov M.
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Agilinko J.
Agnes A.
Agostini C.
Agoston P.
Agrawal A.
Agresta F.
Aguado H.
Aguilar Gonzalez M.
Aguzzoli L.
Ahad S.
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Ahmeidat A.
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Zarabini A. G.
Zatecky J.
Zegarac M.
Zelic M.
Zeller N.
Zengin A. K.
Zerbib P.
Zervas K.
Zese M.
Zhang H.
Zivanovic M.
Zivkovic M.
Zizzo M.
Zografos C.
Zonta S.
Zorrilla Ortuzar J.
Zourntou S.
Zouzoulas D.
Zubaidi A.
Zullo A.
Publication venue: J Clin Oncol
Publication date: 01/01/2020
Field of study

PURPOSE: As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19-free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS: This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19-free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS: Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19-free surgical pathways. Patients who underwent surgery within COVID-19-free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19-free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score-matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19-free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION: Within available resources, dedicated COVID-19-free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks

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Institutional Research Information System University of Turin

Elective cancer surgery in COVID-19-free surgical pathways during the SARS-CoV-2 pandemic: An international, multicenter, comparative cohort study

Author: Aawsaj Y.
Abad Gurumeta A.
Abad-Motos A.
Abate E.
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Abbadessa F.
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Abbott D.
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Abd Elazeem H. A. S.
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Abdelrahman A.
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Abdelsamed A.
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Aboelkassem Ibrahim A.
Abosamak N. E.
Abou Chaar M. K.
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Aboulkassem H.
Abreu Da Silva A.
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Wali A.
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Wallwork K.
Walton G.
Walton T.
Waqar S. H.
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Waris Farooka M.
Warren O.
Waseem S.
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Westwood E.
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Xenaki S.
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Yahaya A. S.
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Yang W.
Yassin N.
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Yesantharao P.
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Yetkin G.
Yiallourou A.
Yildirim A.
Yildiz A.
Ying Y.
Yip V.
Yordanov S.
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Yousof E. A.
Youssef A.
Youssef M.
Yuksel E.
Yurttas C.
Zacharoulis D.
Zafar S. N.
Zakai D.
Zakaria A. D.
Zakaria R.
Zakaria Z.
Zambelli M. F.
Zambon M.
Zamora L.
Zamvar V.
Zani S.
Zanotti S.
Zanus G.
Zapardiel I.
Zarabini A. G.
Zatecky J.
Zegarac M.
Zelic M.
Zeller N.
Zengin A. K.
Zerbib P.
Zervas K.
Zese M.
Zhang H.
Zivanovic M.
Zivkovic M.
Zizzo M.
Zografos C.
Zonta S.
Zorrilla Ortuzar J.
Zourntou S.
Zouzoulas D.
Zubaidi A.
Zullo A.
Publication venue: 'American Society of Clinical Oncology (ASCO)'
Publication date: 01/01/2021
Field of study

PURPOSE As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19–free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19–free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19–free surgical pathways. Patients who underwent surgery within COVID-19–free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19–free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score–matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19–free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION Within available resources, dedicated COVID-19–free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks

Archivio istituzionale della Ricerca - Università degli Studi di Parma

Prognostic model to predict postoperative acute kidney injury in patients undergoing major gastrointestinal surgery based on a national prospective observational cohort study.

Author: Aamir A
Abbas J
Abbas N
Abbott TEF
Abdalla M
Abdikadir H
Abuhussein N
Acquaah F
Adamson R
Adeleye O
Adeogun A
Adlan A
Aftab R
Afzal Z
Agarwal M
Aglan H
Agnew CJF
Agrawal R
Ahern D
Ahluwalia J
Ahluwalia V
Ahmad A
Ahmad K
Ahmed H
Ahmed I
Ahmed L
Ahmed N
Ahmed P
Ainger E
Ainsworth P
Aishwarya G
Ajibola-Taylor O
Akhbari M
Akhtar A
Akhtar R
Akpenyi O
Al-Ausi M
Al-Huneidi R
Al-Khudairi R
Al-Masri S
Al-Mousawi A
Al-Saadi N
Alagappan A
Alberts J
Alfa-Wali M
Ali A
Ali B
Ali I
Ali M
Ali Q
Ali S
Alturki N
Alwandi A
Amani L
Amarnath T
Amer M
Amin H
Amin MN
Amoah R
Amoah-Arko A
Anandarajah C
Ananthavarathan P
Andah EJE
Andrew K
Andrews H
Ang A
Ang HL
Ang JJ
Ani C
Anilkumar A
Anto N
Anwar S
Apperley H
Appleton S
Aquilina T
Archer M
Arif T
Arneill M
Arnell S
Arnold TJ
Arshad A
Arthur J
Arulkumaran N
Arya J
Asad M
Asemota N
Ashaye T
Ashdown T
Ashour R
Ashraf MR
Ashwood J
Asif U
Atkin G
Atkins B
Attalla M
Aubrey-Jones D
Auckburally S
Auld F
Auluck I
Azam S
Aziz R
Azizi A
Azmi F
Babatunde F
Babu VS
Bachi A
Bagga R
Bains H
Bajwa DS
Baker A
Baker C
Balai E
Balian V
Ball M
Bamford M
Bana R
Banfield DA
Bannard-Smith J
Barai I
Barclay J
Barfi L
Barker C
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Barmayehvar B
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Barnor-Ahiaku E
Baron C
Barr CJ
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Baryan HK
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Bath MF
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Beasley W
Beattie G
Beattie S
Beatty M
Beghal G
Begum F
Behranwala K
Belchos J
Belgaid DR
Belgaumkar A
Bell S
Ben-Gal O
Benchetrit S
Bennett M
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Bernal TL
Bertelli M
Berthaume-Hawkins SD
Best R
Betts A
Bevan K
Bews-Hair M
Bhambra R
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Bhide I
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Birkinshaw F
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Blake E
Blazeby JM
Bleakley A
Bloom I
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Borg CM
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Price M
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Regan H
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STARSurg Collaborative Writing Committee, Data analysis, Steering committee, Advisory group, Regional leads, Collaborators and validators
STARSurg Collaborative Writing Committee, Data analysis, Steering committee, Advisory group, Regional leads, Collaborators and validators, Nepogodiev, D
Stechman M
Stewart D
Stewart E
Stewart H
Stewart R
Stickler E
Stoddart MT
Stokes E
Stott G
Strang S
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Stringfellow TD
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Taylor O
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Taylor Z
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Youssef H
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Zaat S
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Zaver V
Zeng R
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Zheleniakova T
Zhu Y
Zornoza A
Zubikarai G
Zulkifli A
Zuzarte L
Publication venue: 'Wiley'
Publication date: 18/05/2018
Field of study

Background: Acute illness, existing co-morbidities and surgical stress response can all contribute to postoperative acute kidney injury (AKI) in patients undergoing major gastrointestinal surgery. The aim of this study was prospectively to develop a pragmatic prognostic model to stratify patients according to risk of developing AKI after major gastrointestinal surgery. Methods: This prospective multicentre cohort study included consecutive adults undergoing elective or emergency gastrointestinal resection, liver resection or stoma reversal in 2-week blocks over a continuous 3-month period. The primary outcome was the rate of AKI within 7 days of surgery. Bootstrap stability was used to select clinically plausible risk factors into the model. Internal model validation was carried out by bootstrap validation. Results: A total of 4544 patients were included across 173 centres in the UK and Ireland. The overall rate of AKI was 14·2 per cent (646 of 4544) and the 30-day mortality rate was 1·8 per cent (84 of 4544). Stage 1 AKI was significantly associated with 30-day mortality (unadjusted odds ratio 7·61, 95 per cent c.i. 4·49 to 12·90; P < 0·001), with increasing odds of death with each AKI stage. Six variables were selected for inclusion in the prognostic model: age, sex, ASA grade, preoperative estimated glomerular filtration rate, planned open surgery and preoperative use of either an angiotensin-converting enzyme inhibitor or an angiotensin receptor blocker. Internal validation demonstrated good model discrimination (c-statistic 0·65). Discussion: Following major gastrointestinal surgery, AKI occurred in one in seven patients. This preoperative prognostic model identified patients at high risk of postoperative AKI. Validation in an independent data set is required to ensure generalizability

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The University of Manchester - Institutional Repository

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University of Dundee Online Publications

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St George's Online Research Archive

Impact of opioid-free analgesia on pain severity and patient satisfaction after discharge from surgery: multispecialty, prospective cohort study in 25 countries

Author: Aamir Faiqa Binte
Aamir Syed Roohan
Ababneh Adnan
Abbal Muhammad Anas
Abbas Ahmed M
Abbas Mostafa
Abd-Albain Montasir A
Abdalei Abdulwahab
Abdalla Ahmed
Abdalla Ahmed Yassir
Abdalla Mohamed Galal Ali
Abdalla Zainab
Abdallah Mohamed M
Abdalmahmoud Noon Ezzeldien
Abdalsadeg Rowa
Abdelaal Ahmed M
Abdelbagi Alnazeer Y
Abdelbaky Mostafa
Abdelbaset Doaa
AbdElbaset Esraa
Abdelbast Menhag
Abdelfatah Mohammed Abdelnasser
Abdelgawad Samia
Abdelhamid Mohamed M
Abdeljaber Mahmoud
Abdelkhalig Mubarak
Abdelmaksoud Mohamed
Abdelmeguid Rana
Abdelmelek Dhia Errahmane
Abdelnaeam Samah
Abdelnasser Mohammad K
Abdelrahim Najwa
Abdelrahman Amira
Abdelrahman Ayman
Abdelsalam Hebatalla
Abdelsamed Enas Abdelbaset
Abdelwahab Khaled
Abdoun Meriem
Abdulali Fatima
Abdulaziz Mohamed
Abdulla Dheba Almukhtar
Abdullah Bahiyah
Abdullah Bahiyah
Abdullah Walaa
Abdullahi Habiba Ibrahim
Abdulrahman Ahmed
Abdulrasheed Lubabatu
Abdulwahed Eman
Abdulwahed Eman
Abeysirigunawardana Dewmi
Abidin Muhammad Fihmi Zainal
Abiola Olukayode
Abiyere Henry
Abodina Ahmed Mohammed
Aboelela Reham
AboElfarh Hadeer Elsaeed
Aboudlal Husein
AbouHiekal Osama
Aboulfotouh Ahmed
Abozid Anwaar
Abubaker Noora
Abubaker Noora
Abufanas Asma
Abughanima Mahmoud
Abuhashem Shehab
Abulafia Daniel
Abushaala Fatima
Abushanab Khaled
AbuShawareb Issa
Abuuqteish Hamza
Abuzaho Amany
Achem Arome
Adam Eithar
Adam Mohammed
Adam Mohammed A
Addalla Mohamed
Addley Jordan
Adeleye Gbadebo
Adeniyi Adebayo
Adewole Nathaniel
Adeyemo Olabisi
Adeyeye Ademola
Adeyeye Ademola
Adly Michael
Adnan Siti Nasyirah Nisya
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Ads Alaa Mohamed
Adze Joel Amwe
Afeikhena Ehis
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Agilla Hamza
Agnew Emilie
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Ahmad Zatul Akmar
Ahmed Abdalla
Ahmed Ahmed
Ahmed Ahmed
Ahmed Alaaaldeen
Ahmed Entisar
Ahmed Habeeba
Ahmed Hatem
Ahmed Reem
Ahmed Rehab
Ahmed Rihab
Ahmed Rogia Ahmed Abdalla
Ahmed Ruaa
Ahmed Sharwany
Ahmed Uzair
Ahmed Wahiba
Ahmeed Sultan
Airede Lydia Regina
Aitchison Lori
Ajredini Mirac
Ajulo Adeshina A
Akaba Godwin
Akasha Mazin
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Akbuz Seyma Orcan
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Akpamgbo Chukwunonso Nnamdi
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Al-Quossi Mohammed
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Alhadad Qamrah
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Alharam Abtisam
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Garba Mohammad Albuhari
Garcia Sara
García Patricia Ludivina González
Garton Briar
Garza Alejandro Quiroga
Garza Francisco Javier Arrambide
Gattesco Davide
Gattulli Domenico
Gebeh Alpha
Gecici Mehmet Emre
Gemici Aylin
Geng Ruxi
Gentle Juliette
George Akhita
George Ria
Gera Sahil
Gernhoefer Erin
Ghaly Moheb
Ghandi Kushan
Ghanem Sohila
Ghemmied Malak
Ghmagh Rawia
Ghmagh Reem
Giannakopoulos Konstantinos S
Gidiem Doaa
Gill Sonia
Gilmore Paul
Gineeb Hana Yousef
Giurgius Mary
Giuzzardi Giulia
Glyn Tamara
Glynatsis John
Glynatsis John
Goddard Kim
Goh Sarah
Goh Sarah
Goh Sarah
Gojnich Amy
Golani Shalni
Goldfinch Elisabeth
Goldsmith Oliver
Golja Damian
Goonawardena Janindu
Gopal Hemashree
Gorgone Mara
Gould Madeline
Gover Tolga
Grada Maren
Grandi Alyssia De
Graziadei Vivien
Green Jemma
Greenwood Emily
Greig Hannah
Grillea Giorgia
Groot Julia De
Gross Hannah
Guerra Ethel Valeria Orta
Guerra-Juárez Yesika Alejandra
Guizzardi Giulia
Gunasekara Aashrinee De Silva Abeweera
Gundara Justin
Guner Ali
Gunn Emma
Guo Oscar
Gündoğdu Adnan
Gweder Rima
Gyftopoulos Argyrios
Hadi Arwa
Hadi Arwa
Haege Emma
Haggag Zeyad
Hakak Fatima
Halawa Mohamed
Hamad Huda
Hamdy Ahmed
Hamdy Omar
Hamer Peter
Hamid Hytham K S
Hammouri Ibraheem
Hamoda Esraa
hamoud Mohammad Al
Hamza Alla Aldeen
Hana Kerolous
Hanan Aishath
Hantes Michael
Harb Fatma
Hardidge Andrew
Hares Mohamed M
Hariharan Shubhang
Harmston Christopher
Haroon Ola
Harris Alasdair
Harrison Ella
Hasan Najat Ben
Hashem Ahmed Mohamed
Hashem Boshra
Hassan Majd
Hassan Mohamed
Hassan Muaz
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Hassan Suhaib
Hassan Tawfieg
Hassan Yusuf
Hassanein Mahmoud
Hau Yin Chi Hebe
Hauptman Samantha
Hauptman Samantha
Haximolla Hodo
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Healy Tom
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Heigan Rachael
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Hernandez Gilmer Omar Perez
Hewton Lewis
Hezam Abdulhakim
Hilail Ihab Abu
Hilal Nadir
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Hilder Amie
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Ho Jess
Ho Jess
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Hou Zhen
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Huang Meileen
Huang Sarah
Hui Ally
Hung Wing
Husein Abrar
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Hussein Aisha
Hussien Ahmed
Hussien Aya
Hussien Tarek A
Ibiyemi Femi
Ibraheem Gbadebo Hakeem
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Ifoto Oghenekaro
Iftikhar Hareem
Imran Aliza
Incoll Ian
Innes Michael
Ioannidis Orestis
Ioannidis Orestis
Ioannidis Orestis
Isaac Hope
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Isah Dennis Anthony
Isahak Mohamed Izzad
Isais Jorge Arath Rosales
Ismail Samir
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Isopi Claudio
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Iya Abdulkarim
Izgis Aylin
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Jabur Aiden
Jabur Aiden
Jabur Aiden
Jaffry Kumail
Jaffry Kumail
Jakanovski Philip
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Jamali Salma
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Jangam Aishwarya
Jangra Muskan
Javed Imran
Jawa Timothy
Jayatilleke Shenuka
Jayyab Mustafa Abu
Jeffery Fraser
Jenkins Gregory
Jeyamohan Ragavi
Jeyarajan Deepak Rajan
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Jimenez Ramirez Lia Jasmin
Jin Rong
Jinu Puja
Jollow David
Joseph Fashe
Joseph Nejo
Joshi Divyanshu
Joshi Krishma
Ju William
Juha Nida
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Juwaheer Ghanisht
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Kache Stephen Akau
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Kaiser Nicole
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Kamath Aditi
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Koh Imogen
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Kumove Matt
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Lagana Bernard
Lai Sherman
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Loughnan Rachael
Loutzidou Lydia
Lown Ashleigh
Lu Andi
Lu Christine
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Luo Jonathan
Luo Michel
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Luu Emily
Luu Rebecca
Ly Victor
Ma Vanessa
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Maali Mohammed
Maccormick Andrew
Machairas Nikolaos
Mackay Thomas
Macnab Brooke
Maddern Guy
Maddern Guy
Maestri Marco
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Mahdy Magdy
Maher Hager
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Mahmoud Ahmed Omar
Mahmoud Fathia
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Mahmud Ahmad
Mahnoor
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Malasah Mohammad
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Mandhan Kajal
Manoglu Berke
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Martin Jennifer
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Min Seojung
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Mohamed Hanaa
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Mohamed Maab
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Mohamed Omer
Mohamed Shakir
Mohammed Caleb
Mohammed Haitham
Mohammed Hawa Mohammed Hassan
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Mohammed Sara
Mohammed Taofiq Olayinka
Mohammed Tasneem
Mohammed-Durosinlorun Amina Abosede
Mohmmed Sara
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Naicker Leshya
Naicker Leshya
Naiker Leshya
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Namburi Manideep
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Nanez Daniel Mauricio Bolanos
Naqeeb Ahmed
Nara Naveen
Narayan Aditya
Nasereddin Mahmoud
Nasr Mohammed Saif Al
Nasr Mouna
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Natarajan Ragul
Nath Upanmanyu
Natsheh Zeinab
Nebbar Oualid
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Neo Eu Ling
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Nguyen Kevin
Nguyen Kim
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Ngwan David Wujika
Nicholson Amy
Niknami Behzad
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Ningi Adamu Bala
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Noordin Shahryar
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Nosseir Omar
Noureldin Youssef Ali
Ntalouka Maria
Nukala Sai Keerthana
Nusem Iulian
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O'neil Chris
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Odisho Ramin
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Ogidi Adetolu
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Ohis Christina
Okkabaz Nuri
Okon Seubong-Abasi Imoh
Oksak Ilayda
Okunlola Abiodun
Okunlola Cecilia
Omar Basma
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Omer Ahmed Ali
Omur Mert
Oncel Muhammed Miran
Oncel Mustafa
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Ong Elynn
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Pai Vivian
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Papanikolaou Evangelos
Parajuli Dikshya
Parange Anupam
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Park Melissa
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Patel Diya
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Patil Aditya
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Pehlivan Dilan
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Phu Rachel
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Pillai Anil Kumar Sree Kumar
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Podder Nayanika
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Prasad Shaamnil
Prasad Shalvin
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Qazi Arisha
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Rais Mounira
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Ramadan Mohamed
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Rasheed Ayat
Raslan Bassma
Rasslan Esraa
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Raubenheimer Kyle
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Rhuma Heba
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Roshdy Mo'men
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Ross Poppy
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Roth Charles
Rottoli Matteo
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Rusli Siti Mayuha
Russo Iris Shari
Saad Mahmoud M
Saada Hind
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Sahin Melek
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umar Abubakar
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Yoon Si Woo
You Ha Seong
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Yousri Mohamed
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Youssef Arkan
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Yu Victor
Yuan Grace
Yue Bosco
Yue Tiffany
Yunos Mohamed Haseef Mohamed
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Yuzgec Ayse Nilufer
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Zaed Moahmed
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Zaheer Adil
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Zeng Raymond
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Zengin Kagan
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Zheng Helen
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Zou Peishan
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Zwain Yasir Adnan
Zyul'korneeva Sof'ya
‏Aladna ‏Abdallah
‏Aljoumaa ‏Abdullah
‏Nawfal ‏Hamdi
‏Niazi ‏Ammar
Publication venue
Publication date: 01/01/2024
Field of study

Background: Balancing opioid stewardship and the need for adequate analgesia following discharge after surgery is challenging. This study aimed to compare the outcomes for patients discharged with opioid versus opioid-free analgesia after common surgical procedures.Methods: This international, multicentre, prospective cohort study collected data from patients undergoing common acute and elective general surgical, urological, gynaecological, and orthopaedic procedures. The primary outcomes were patient-reported time in severe pain measured on a numerical analogue scale from 0 to 100% and patient-reported satisfaction with pain relief during the first week following discharge. Data were collected by in-hospital chart review and patient telephone interview 1 week after discharge.Results: The study recruited 4273 patients from 144 centres in 25 countries; 1311 patients (30.7%) were prescribed opioid analgesia at discharge. Patients reported being in severe pain for 10 (i.q.r. 1-30)% of the first week after discharge and rated satisfaction with analgesia as 90 (i.q.r. 80-100) of 100. After adjustment for confounders, opioid analgesia on discharge was independently associated with increased pain severity (risk ratio 1.52, 95% c.i. 1.31 to 1.76; P < 0.001) and re-presentation to healthcare providers owing to side-effects of medication (OR 2.38, 95% c.i. 1.36 to 4.17; P = 0.004), but not with satisfaction with analgesia (beta coefficient 0.92, 95% c.i. -1.52 to 3.36; P = 0.468) compared with opioid-free analgesia. Although opioid prescribing varied greatly between high-income and low- and middle-income countries, patient-reported outcomes did not.Conclusion: Opioid analgesia prescription on surgical discharge is associated with a higher risk of re-presentation owing to side-effects of medication and increased patient-reported pain, but not with changes in patient-reported satisfaction. Opioid-free discharge analgesia should be adopted routinely

Archivio istituzionale della ricerca - Alma Mater Studiorum Università di Bologna

Dokuz Eylul University Research Information System

The global burden of cancer attributable to risk factors, 2010-19 : a systematic analysis for the Global Burden of Disease Study 2019

Author: Aali Amirali
Abbas Qamar
Abbasi Behzad
Abbasi-Kangevari Mohsen
Abbasi-Kangevari Zeinab
Abbastabar Hedayat
Abd-Elsalam Sherief
Abdelmasseh Michael
Abdelwahab Ahmed Abdelwahab
Abdoli Gholamreza
Abdulkader Rizwan Suliankatchi
Abdulkadir Hanan Abdulkadir
Abedi Aidin
Abegaz Kedir Hussein
Abidi Hassan
Aboagye Richard Gyan
Abolhassani Hassan
Absalan Abdorrahim
Abtew Yonas Derso
Abu-Gharbieh Eman
Achappa Basavaprabhu
Acheson Alistair R
Acuna Juan Manuel
Addison Daniel
Addo Isaac Yeboah
Adegboye Oyelola A
Adesina Miracle Ayomikun
Adnan Mohammad
Adnani Qorinah Estiningtyas Sakilah
Advani Shailesh M
Afrin Sumia
Afzal Muhammad Sohail
Aggarwal Manik
Ahinkorah Bright Opoku
Ahmad Araz Ramazan
Ahmad Rizwan
Ahmad Sajjad
Ahmad Sohail
Ahmadi Sepideh
Ahmed Haroon
Ahmed Luai A
Ahmed Muktar Beshir
Aiman Wajeeha
Ajami Marjan
Akalu Gizachew Taddesse
Akbarzadeh-Khiavi Mostafa
Aklilu Addis
Akonde Maxwell
Akunna Chisom Joyqueenet
Al-Hanawi Mohammed Khaled
Al-Maweri Sadeq Ali Ali
Al-Raddadi Rajaa M
Al-Rifai Rami H Hani
Al-Sabah Salman Khalifah
Al-Tammemi Ala'a B
Alahdab Fares
Alanezi Fahad Mashhour
Alanzi Turki M
Alessy Saleh Ali
Algammal Abdelazeem M
Alhassan Robert Kaba
Ali Adel Hajj
Ali Beriwan Abdulqadir
Ali Hiwa Abubaker
Ali Liaqat
Ali Syed Shujait
Alimohamadi Yousef
Alipour Vahid
Aljunid Syed Mohamed
Alkhayyat Motasem
Almustanyir Sami
Alonso Nivaldo
Alqalyoobi Shehabaldin
Altawalah Haya
Alvis-Guzman Nelson
Amare Firehiwot
Ameyaw Edward Kwabena
Amirzade-Iranaq Mohammad Hosein
Amu Hubert
Amusa Ganiyu Adeniyi
Ancuceanu Robert
Anderson Jason A
Animut Yaregal Animut
Anoushiravani Amir
Anoushirvani Ali Arash
Ansari-Moghaddam Alireza
Ansha Mustafa Geleto
Antony Benny
Antwi Maxwell Hubert
Anwar Sumadi Lukman
Anwer Razique
Anyasodor Anayochukwu Edward
Arab-Zozani Morteza
Arabloo Jalal
Aremu Olatunde
Argaw Ayele Mamo
Ariffin Hany
Aripov Timur
Arshad Muhammad
Artaman Al
Arulappan Judie
Aruleba Raphael Taiwo
Aryannejad Armin
Asaad Malke
Asemahagn Mulusew A
Asemi Zatollah
Asghari-Jafarabadi Mohammad
Ashraf Tahira
Assadi Reza
Athar Mohammad
Athari Seyyed Shamsadin
Atout Maha Moh'd Wahbi
Attia Sameh
Aujayeb Avinash
Ausloos Marcel
Avila-Burgos Leticia
Avval Atlas Haddadi
Awedew Atalel Fentahun
Awoke Mamaru Ayenew
Awoke Tewachew
Ayana Tegegn Mulatu
Ayen Solomon Shitu
Azadi Davood
Azadnajafabad Sina
Azami-Aghdash Saber
Azanaw Melkalem Mamuye
Azangou-Khyavy Mohammadreza
Azizi Hosein
Azzam Ahmed YY
Babajani Amirhesam
Badar Muhammad
Badiye Ashish D
Baghcheghi Nayereh
Bagheri Nader
Bagherieh Sara
Bahadory Saeed
Baig Atif Amin
Bain Luchuo Engelbert
Baker Jennifer L
Bakhtiari Ahad
Bakshi Ravleen Kaur
Banach Maciej
Banerjee Indrajit
Bardhan Mainak
Barone-Adesi Francesco
Barra Fabio
Barrow Amadou
Bashir Nasir Z
Bashiri Azadeh
Basu Saurav
Batiha Abdul-Monim Mohammad
Begum Aeysha
Bekele Alehegn Bekele
Belay Alemayehu Sayih
Belete Melaku Ashagrie
Belgaumi Uzma Iqbal
Bell Arielle Wilder
Belo Luis
Benzian Habib
Berhie Alemshet Yirga
Bermudez Amiel Nazer C
Bernabe Eduardo
Bhagavathula Akshaya Srikanth
Bhala Neeraj
Bhandari Bharti Bhandari
Bhardwaj Nikha
Bhardwaj Pankaj
Bhattacharyya Krittika
Bhojaraja Vijayalakshmi S
Bhuyan Soumitra S
Bibi Sadia
Bicer Burcu Kucuk
Bilchut Awraris Hailu
Bintoro Bagas Suryo
Biondi Antonio
Birega Mesfin Geremaw Birega
Birhan Habitu Eshetu
Bjørge Tone
Blyuss Oleg
Bodicha Belay Boda Abule
Bohan Phillip M Kemp
Bolla Srinivasa Rao
Boloor Archith
Bosetti Cristina
Braithwaite Dejana
Brauer Michael
Brenner Hermann
Briko Andrey Nikolaevich
Briko Nikolay Ivanovich
Buchanan Christina Maree
Bulamu Norma B
Bustamante-Teixeira Maria Teresa
Butt Muhammad Hammad
Butt Nadeem Shafique
Butt Zahid A
Cao Chao
Cao Yin
Carreras Giulia
Carvalho Márcia
Cembranel Francieli
Cerin Ester
Chakraborty Promit Ananyo
Chandrasekar Viveksandeep Thoguluva
Charalampous Periklis
Chattu Vijay Kumar
Chimed-Ochir Odgerel
Chirinos-Caceres Jesus Lorenzo
Cho Daniel Youngwhan
Cho William CS
Christopher Devasahayam J
Chu Dinh-Toi
Chukwu Isaac Sunday
Cohen Aaron J
Collaborators GBD 2019 Cancer Risk Factors
Compton Kelly
Conde Joao
Cortés Sandra
Costa Vera Marisa
Cruz-Martins Natália
Culbreth Garland T
Cámera Luis Alberto
Dadras Omid
Dagnaw Fentaw Teshome
Dahlawi Saad MA
Dai Xiaochen
Dandona Lalit
Dandona Rakhi
Daneshpajouhnejad Parnaz
Danielewicz Anna
Dao An Thi Minh
Darwesh Aso Mohammad
Das Saswati
Davitoiu Dragos Virgil
De la Hoz Fernando Pio
Debela Sisay Abebe
Dehghan Azizallah
Dehkordi Javad Javad Aminian
Demisse Biniyam
Demisse Fitsum Wolde
Denova-Gutiérrez Edgar
Derakhshani Afshin
Dereje Diriba
Deribe Kalkidan Solomon
Desai Rupak
Desalegn Markos Desalegn
Desideri Lorenzo Ferro
Dessalegn Fikadu Nugusu
Dessalegni Samuel Abebe A
Dessie Gashaw
Desta Abebaw Alemayehu
Dewan Syed Masudur Rahman
Dharmaratne Samath Dhamminda
Dhimal Meghnath
Dianatinasab Mostafa
Diao Nancy
Diaz Daniel
Digesa Lankamo Ena
Dixit Shilpi Gupta
Doaei Saeid
Doan Linh Phuong
Doku Paul Narh
Dongarwar Deepa
dos Santos Florentino Luciano Caetano
dos Santos Wendel Mombaque
Driscoll Tim Robert
Dsouza Haneil Larson
Durojaiye Oyewole Christopher
Edalati Sareh
Eghbalian Fatemeh
Ehsani-Chimeh Elham
Eini Ebrahim
Ekholuenetale Michael
Ekundayo Temitope Cyrus
Ekwueme Donatus U
El-Huneidi Waseem
Elbahnasawy Mostafa Ahmed
Elbarazi Iffat
Elghazaly Hesham
Elhadi Muhammed
Emamian Mohammad Hassan
Enyew Daniel Berhanie
Erkhembayar Ryenchindorj
Eshetu Tegegne
Eshrati Babak
Eskandarieh Sharareh
Esmaeili Elham Davtalab
Espinosa-Montero Juan
Etaee Farshid
Etemadimanesh Azin
Eyayu Tahir
Ezeonwumelu Ifeanyi Jude
Ezzikouri Sayeh
Fagbamigbe Adeniyi Francis
Fahimi Saman
Fakhradiyev Ildar Ravisovich
Faraon Emerito Jose A
Fares Jawad
Farmany Abbas
Farooque Umar
Farrokhpour Hossein
Fasanmi Abidemi Omolara
Fatehizadeh Ali
Fatima Wafa
Fattahi Hamed
Fekadu Ginenus
Feleke Berhanu Elfu
Ferrari Allegra Allegra
Ferrero Simone
Filip Irina
Fischer Florian
Fonseca Mariana Gaspar
Force Lisa M
Foroumadi Roham
Foroutan Masoud
Fukumoto Takeshi
Gaal Peter Andras
Gad Mohamed M
Gadanya Muktar A
Gaipov Abduzhappar
Galehdar Nasrin
Gallus Silvano
Garg Tushar
Gebremariam Yosef Haile
Gebremeskel Teferi Gebru
Gebremichael Mathewos Alemu
Geda Yohannes Fikadu
Gela Yibeltal Yismaw
Gemeda Belete Negese Belete
Getachew Melaku
Getachew Motuma Erena
Ghaffari Kazem
Ghafourifard Mansour
Ghamari Seyyed-Hadi
Ghassemi Fariba
Ghimire Ajnish
Ghith Nermin
Gholamalizadeh Maryam
Ghozy Sherief
Gilani Syed Amir
Gill Paramjit Singh
Ginindza Themba G
Gizaw Abraham Tamirat T
Glasbey James C
Godos Justyna
Goel Amit
Golechha Mahaveer
Goleij Pouya
Golinelli Davide
Golitaleb Mohamad
Gorini Giuseppe
Goulart Bárbara Niegia Garcia
Grosso Giuseppe
Guadie Habtamu Alganeh
Gubari Mohammed Ibrahim Mohialdeen
Gudayu Temesgen Worku
Guerra Maximiliano Ribeiro
Gunawardane Damitha Asanga
Gupta Bhawna
Gupta Sapna
Gupta Veer Bala
Gupta Vivek Kumar
Gurara Mekdes Kondale
Guta Alemu
Habibzadeh Parham
Hafezi-Nejad Nima
Haj-Mirzaian Arvin
Halboub Esam S
Halimi Aram
Halwani Rabih
Hamad Hanadi Al
Hamadeh Randah R
Hameed Sajid
Hamidi Samer
Hanif Asif
Hariri Sanam
Harlianto Netanja I
Haro Josep Maria
Hartono Risky Kusuma
Hasaballah Ahmed I
Hasan SM Mahmudul
Hasani Hamidreza
Hashemi Seyedeh Melika
Hassan Abbas M
Hassanipour Soheil
Hay Simon I
Hayat Khezar
Heidari Golnaz
Heidari Mohammad
Heidarymeybodi Zahra
Henrikson Hannah Jacqueline
Herrera-Serna Brenda Yuliana
Herteliu Claudiu
Hezam Kamal
Hiraike Yuta
Hlongwa Mbuzeleni Mbuzeleni
Holla Ramesh
Holm Marianne
Horita Nobuyuki
Hoseini Mohammad
Hossain Mahbub
Hossain Mohammad Bellal Hossain
Hosseini Mohammad-Salar
Hosseinzadeh Ali
Hosseinzadeh Mehdi
Hostiuc Mihaela
Hostiuc Sorin
Househ Mowafa
Huang Junjie
Hugo Fernando N
Humayun Ayesha
Hussain Salman
Hussein Nawfal R
Hwang Bing-Fang
Ibitoye Segun Emmanuel
Iftikhar Pulwasha Maria
Ikuta Kevin S
Ilesanmi Olayinka Stephen
Ilic Irena M
Ilic Milena D
Immurana Mustapha
Innos Kaire
Iranpour Pooya
Irham Lalu Muhammad
Isfahani Haleh Mousavi
Islam Rakibul M
Islam Shariful
Islami Farhad
Ismail Nahlah Elkudssiah
Isola Gaetano
Iwagami Masao
J Linda Merin
Jabbari Seyed Hossein Yahyazadeh
Jafari Amirhossein Azari
Jaiswal Abhishek
Jakovljevic Mihajlo
Jalili Mahsa
Jalilian Shahram
Jamshidi Elham
Jang Sung-In
Jani Chinmay T
Javaheri Tahereh
Jayarajah Umesh Umesh
Jayaram Shubha
Jazayeri Seyed Behzad
Jebai Rime
Jemal Bedru
Jeong Wonjeong
Jha Ravi Prakash
Jindal Har Ashish
John-Akinola Yetunde O
Jonas Jost B
Jonasson Junmei Miao
Joo Tamas
Joseph Nitin
Joukar Farahnaz
Jozwiak Jacek Jerzy
Julian Guilherme Silva
Jürisson Mikk
Kabir Ali
Kacimi Salah Eddine Oussama
Kadashetti Vidya
Kahe Farima
Kakodkar Pradnya Vishal
Kalankesh Laleh R
Kalankesh Leila R
Kalhor Rohollah
Kamal Vineet Kumar
Kamangar Farin
Kamath Ashwin
Kanchan Tanuj
Kandaswamy Eswar
Kandel Himal
Kandel Sandhya Neupane
Kang HyeJung
Kanno Girum Gebremeskel
Kapoor Neeti
Kar Sitanshu Sekhar
Karanth Shama D
Karaye Ibraheem M
Karch André
Karimi Amirali
Kashani Hamid Reza Khayat
Kassa Bekalu Getnet
Katoto Patrick DMC
Kauppila Joonas H
Kaur Harkiran
Kebede Abinet Gebremickael
Keikavoosi-Arani Leila
Kejela Gemechu Gemechu
Keramati Maryam
Keykhaei Mohammad
Khajuria Himanshu
Khan Abbas
Khan Abdul Aziz Khan
Khan Ejaz Ahmad
Khan Gulfaraz
Khan Moien AB
Khan Nuruzzaman
Khanali Javad
Khaneghah Amin Mousavi
Khatab Khaled
Khatatbeh Moawiah Mohammad
Khatib Mahalaqua Nazli
Khayamzadeh Maryam
Khezeli Mehdi
Khodadost Mahmoud
Kim Min Seo
Kim Yun Jin
Kisa Adnan
Kisa Sezer
Klugar Miloslav
Klugarová Jitka
Kocarnik Jonathan M
Kolahi Ali-Asghar
Kolkhir Pavel
Kompani Farzad
Koul Parvaiz A
Koyanagi Ai
Krishan Kewal
Krishnamoorthy Yuvaraj
Kugbey Nuworza
Kulimbet Mukhtar
Kumar Akshay
Kumar G Anil
Kumar Narinder
Kurmi Om P
Kuttikkattu Ambily
La Vecchia Carlo
Lahiri Arista
Lal Dharmesh Kumar
Lan Qing
Landires Iván
Lang Justin J
Langroudi Ashkan Pourabhari
Larijani Bagher
Lasrado Savita
Lau Jerrald
Lauriola Paolo
Laxminarayana Sindhura Lakshmi Koulmane
Ledda Caterina
Lee Sang-woong
Lee Shaun Wen Huey
Lee Wei-Chen
Lee Yeong Yeh
Lee Yo Han
Legesse Samson Mideksa
Leigh James
Leong Elvynna
Li Ming-Chieh
Lim Stephen S
Liu Gang
Liu Jue
Lo Chun-Han
Lohiya Ayush
Lopukhov Platon D
Lorenzovici László
Lotfi Mojgan
Loureiro Joana A
Lunevicius Raimundas
Lám Judit
Madadizadeh Farzan
Mafi Ahmad R
Magdeldin Sameh
Mahesh PA
Mahjoub Soleiman
Mahmoodpoor Ata
Mahmoudi Morteza
Mahmoudimanesh Marzieh
Mahumud Rashidul Alam
Majeed Azeem
Majidpoor Jamal
Makki Alaa
Makris Konstantinos Christos
Malekpour Mohammad-Reza
Malekzadeh Reza
Malik Ahmad Azam
Malleshappa Sudeep K Siddappa
Mallhi Tauqeer Hussain
Mallya Sneha Deepak
Mamun Mohammed A
Manda Ana Laura
Manjula S
Mansour-Ghanaei Fariborz
Mansouri Borhan
Mansournia Mohammad Ali
Mantovani Lorenzo Giovanni
Martini Santi
Martorell Miquel
Masoudi Sahar
Masoumi Seyedeh Zahra
Matei Clara N
Mathews Elezebeth
Mathur Manu Raj
Mathur Vasundhara
McKee Martin
Meena Jitendra Kumar
Mehmood Khalid
Mehrotra Ravi
Melese Addisu
Mendoza Walter
Menezes Ritesh G
Mengesha SIsay Derso
Mensah Laverne G
Mentis Alexios-Fotios A
Mera-Mamián Andry Yasmid Mera
Meretoja Tuomo J
Merid Mehari Woldemariam
Mersha Amanual Getnet
Meselu Belsity Temesgen
Meshkat Mahboobeh
Mestrovic Tomislav
Miazgowski Tomasz
Michalek Irmina Maria
Mijena Gelana Fekadu Worku
Miller Ted R
Mir Shabir Ahmad
Mirinezhad Seyed Kazem
Mirmoeeni Seyyedmohammadsadeq
Mirza-Aghazadeh-Attari Mohammad
Mirzaei Hamed
Mirzaei Hamid Reza
Misganaw Abay Sisay
Misra Sanjeev
Mohammad Karzan Abdulmuhsin
Mohammadi Esmaeil
Mohammadi Mokhtar
Mohammadian-Hafshejani Abdollah
Mohammadpourhodki Reza
Mohammed Arif
Mohammed Shafiu
Mohan Syam
Mohseni Mohammad
Moka Nagabhishek
Mokdad Ali H
Molassiotis Alex
Molla Meseret Derbew
Molokhia Mariam
Momenzadeh Kaveh
Momtazmanesh Sara
Monasta Lorenzo
Mons Ute
Montasir Ahmed Al
Montazeri Fateme
Montero Arnulfo
Moosavi Mohammad Amin
Moradi Abdolvahab
Moradi Yousef
Moraga Paula
Morawska Lidia
Morrison Shane Douglas
Morze Jakub
Mosapour Abbas
Mostafavi Ebrahim
Mousavi Seyyed Meysam
Mpundu-Kaambwa Christine
Mubarik Sumaira
Mulita Francesk
Munblit Daniel
Munro Sandra B
Murillo-Zamora Efrén
Murray Christopher JL
Musa Jonah
Nabhan Ashraf F
Nagarajan Ahamarshan Jayaraman
Nagaraju Shankar Prasad
Nagel Gabriele
Naghipour Mohammadreza
Naimzada Mukhammad David
Nair Tapas Sadasivan
Naqvi Atta Abbas
Narayana Aparna Ichalangod
Nasab Entezar Mehrabi
Nassereldine Hasan
Natto Zuhair S
Navashenaq Jamshid Gholizadeh
Nayak Biswa Prakash
Ndejjo Rawlance
Nduaguba Sabina Onyinye
Negash Wogene Wogene
Nejadghaderi Seyed Aria
Nejati Kazem
Niazi Robina Khan
Noor Nurulamin M
Noori Maryam
Noroozi Nafise
Nour Mohammad Ghasemi
Nouraei Hasti
Nowroozi Ali
Nuñez-Samudio Virginia
Nzoputam Chimezie Igwegbe
Nzoputam Ogochukwu Janet
Oancea Bogdan
Odukoya Oluwakemi Ololade
Oghenetega Onome Bright
Ogunsakin Ropo Ebenezer
Oguntade Ayodipupo Sikiru
Oh In-Hwan
Okati-Aliabad Hassan
Okekunle Akinkunmi Paul
Olagunju Andrew T
Olagunju Tinuke O
Olakunde Babayemi Oluwaseun
Olufadewa Isaac Iyinoluwa
Omer Emad
Omonisi Abidemi E Emmanuel
Ong Sokking
Onwujekwe Obinna E
Orru Hans
Otstavnov Stanislav S
Oulhaj Abderrahim
Oumer Bilcha
Owopetu Oluwatomi Funbi
Oyinloye Babatunji Emmanuel
Padron-Monedero Alicia
Padubidri Jagadish Rao
Pakbin Babak
Pakshir Keyvan
Pakzad Reza
Palicz Tamás
Pana Adrian
Pandey Anamika
Pandey Ashok
Pant Suman
Pardhan Shahina
Park Eun-Cheol
Park Eun-Kee
Park Seoyeon
Patel Jay
Pati Siddhartha
Paudel Rajan
Paudel Uttam
Paun Mihaela
Penberthy Louise
Peng Minjin
Pereira Jeevan
Pereira Renato B
Perna Simone
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Pestell Richard G
Pezzani Raffaele
Piccinelli Cristiano
Pillay Julian David
Piracha Zahra Zahid
Pischon Tobias
Postma Maarten J
Pourshams Akram
Pourtaheri Naeimeh
Prashant Akila
Qadir Mirza Muhammad Fahd
Quintanilla Beatriz Paulina Ayala
Rabiee Mohammad
Rabiee Navid
Rad Elaheh Malakan
Radfar Amir
Radhakrishnan Raghu Anekal
Radhakrishnan Venkatraman
Raeisi Mojtaba
Rafiee Ata
Rafiei Alireza
Raheem Nasiru
Rahim Fakher
Rahman Mosiur
Rahman Muhammad Aziz
Rahman Obaidur
Rahmani Amir Masoud
Rahmani Shayan
Rahmanian Vahid
Rajai Nazanin
Rajesh Aashish
Ram Pradhum
Ramezanzadeh Kiana
Rana Juwel
Ranabhat Kamal
Ranasinghe Priyanga
Rao Chythra R
Rao Sowmya J
Rashedi Sina
Rashid Tarik Ahmed
Rashidi Amirfarzan
Rashidi Mahsa
Rashidi Mohammad-Mahdi
Ratan Zubair Ahmed
Rawaf David Laith
Rawaf Salman
Rawal Lal
Rawassizadeh Reza
Razeghinia Mohammad Sadegh
Rehman Ashfaq Ur
Rehman Inayat ur
Reitsma Marissa B
Renzaho Andre MN
Rezaei Maryam
Rezaei Nazila
Rezaei Negar
Rezaei Nima
Rezaei Saeid
Rezaeian Mohsen
Rezapour Aziz
Riad Abanoub
Rikhtegar Reza
Rios-Blancas Maria
Roberts Thomas J
Rohloff Peter
Romero-Rodríguez Esperanza
Roshandel Gholamreza
Rwegerera Godfrey M
Saber-Ayad Maha Mohamed
Saberzadeh-Ardestani Bahar
Sabour Siamak
Saddik Basema
Sadeghi Erfan
Saeb Mohammad Reza
Saeed Umar
Safaei Mohsen
Safary Azam
Sahebazzamani Maryam
Sahebkar Amirhossein
Sahoo Harihar
Sajid Mirza Rizwan
Salari Hedayat
Salehi Sana
Salem Marwa Rashad
Salimzadeh Hamideh
Samodra Yoseph Leonardo
Samy Abdallah M
Sanabria Juan
Sankararaman Senthilkumar
Sanmarchi Francesco
Santric-Milicevic Milena M
Saqib Muhammad Arif Nadeem
Sarabi Mostafa Moradi
Sarveazad Arash
Sarvi Fatemeh
Sathian Brijesh
Satpathy Maheswar
Sayegh Nicolas
Schneider Ione Jayce Ceola
Schwarzinger Michaël
Senthilkumaran Subramanian
Sepanlou Sadaf G
Seylani Allen
Seyoum Kenbon
Sha Feng
Shafaat Omid
Shah Pritik A
Shahabi Saeed
Shahid Izza
Shahrbaf Mohammad Amin
Shahsavari Hamid R
Shaikh Masood Ali
Shaka Mohammed Feyisso
Shaker Elaheh
Shannawaz Mohammed
Sharew Mequannent Melaku Sharew
Sharifi Azam
Sharifi-Rad Javad
Sharma Purva
Shashamo Bereket Beyene
Sheikh
Sheikh Aziz
Sheikhbahaei Sara
Sheikhi Rahim Ali
Sheikhy Ali
Shepherd Peter Robin
Shetty Adithi
Shetty Jeevan K
Shetty Ranjitha S
Shibuya Kenji
Shirkoohi Reza
Shirzad-Aski Hesamaddin
Shivakumar KM
Shivalli Siddharudha
Shivarov Velizar
Shobeiri Parnian
Shorofi Seyed Afshin
Shrestha Sunil
Sibhat Migbar Mekonnen
Sidemo Negussie Boti
Silva Diego Augusto Santos
Silva Luís Manuel Lopes Rodrigues
Silvestris Nicola
Simegn Wudneh
Singh Achintya Dinesh
Singh Ambrish
Singh Garima
Singh Harpreet
Singh Jasvinder A
Singh Jitendra Kumar
Singh Paramdeep
Singh Surjit
Sinha Dhirendra Narain
Sinke Abiy H
Siraj Shahjahan
Sitas Freddy
Siwal Samarjeet Singh
Skryabin Valentin Yurievich
Skryabina Anna Aleksandrovna
Socea Bogdan
Soeberg Matthew J
Sofi-Mahmudi Ahmad
Solomon Yonatan
Soltani Reza Darvishi Cheshmeh
Soltani-Zangbar Mohammad Sadegh
Song Suhang
Song Yimeng
Soodejani Moslem Taheri
Sorensen Reed JD
Soshnikov Sergey
Sotoudeh Houman
Sowe Alieu
Sufiyan Mu'awiyyah Babale
Suk Ryan
Suleman Muhammad
Sultana Saima
Sur Daniel
Swamy Sreenivas Narasimha
Syed Zahiruddin Quazi
Szócska Miklós
Tabaeian Seidamir Pasha
Tabari Mohammad Amin Khazeei
Tabarés-Seisdedos Rafael
Tabatabaei Seyyed Mohammad
Tabuchi Takahiro
Tadbiri Hooman
Tahbaz Sahel Valadan
Taheri Ensiyeh
Taheri Majid
Takahashi Ken
Talaat Iman M
Tampa Mircea
Tan Ker-Kan
Tantawi Maha El
Tat Nathan Y
Tat Vivian Y
Tavakoli Ahmad
Tavakoli Arash
Tehrani-Banihashemi Arash
Tekalegn Yohannes
Tesfay Fisaha Haile
Thapar Rekha
Thavamani Aravind
Thomas Nihal
Thomas Nikhil Kenny
Ticoalu Jansje Henny Vera
Tiyuri Amir
Tollosa Daniel Nigusse
Topor-Madry Roman
Toroudi Hamidreza Pazoki
Touvier Mathilde
Tovani-Palone Marcos Roberto
Traini Eugenio
Tran Khanh Bao
Tran Mai Thi Ngoc
Tripathy Jaya Prasad
Ukke Gebresilasea Gendisha
Ullah Irfan
Ullah Saif
Ullah Sana
Unnikrishnan Bhaskaran
Vacante Marco
Vaezi Maryam
Valdez Pascual R
Van Nguyen Nguyen Huy
Vardavas Constantine
Varniab Zahra Shokri
Varthya Shoban Babu
Vaziri Siavash
Velazquez Diana Zuleika
Veroux Massimiliano
Villeneuve Paul J
Violante Francesco S
Vladimirov Sergey Konstantinovitch
Vlassov Vasily
Vo Bay
Vos Theo
Vu Linh Gia
Wadood Abdul Wadood
Waheed Yasir
Walde Mandaras Tariku
Wamai Richard G
Wang Cong
Wang Fang
Wang Ning
Wang Yu
Ward Paul
Waris Abdul
Westerman Ronny
Wickramasinghe Nuwan Darshana
Woldemariam Melat
Woldu Berhanu
Xiao Hong
Xu Rixing
Xu Suowen
Xu Xiaoyue
Yadav Lalit
Yang Lin
Yazdanpanah Fereshteh
Yeshaw Yigizie
Yismaw Yazachew
Yonemoto Naohiro
Younis Mustafa Z
Yousefi Zabihollah
Yousefian Fatemeh
Yu Chuanhua
Yu Yong
Yunusa Ismaeel
Zahir Mazyar
Zaki Nazar
Zaman Burhan Abdullah
Zangiabadian Moein
Zare Fariba
Zare Iman
Zareshahrabadi Zahra
Zarrintan Armin
Zastrozhin Mikhail Sergeevich
Zeineddine Mohammad A
Zhang Dongyu
Zhang Jianrong
Zhang Yunquan
Zhang Zhi-Jiang
Zhou Linghui
Zodpey Sanjay
Zoladl Mohammad
Šekerija Mario
Publication venue
Publication date: 01/01/2022
Field of study

Background Understanding the magnitude of cancer burden attributable to potentially modifiable risk factors is crucial for development of effective prevention and mitigation strategies. We analysed results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 to inform cancer control planning efforts globally. Methods The GBD 2019 comparative risk assessment framework was used to estimate cancer burden attributable to behavioural, environmental and occupational, and metabolic risk factors. A total of 82 risk-outcome pairs were included on the basis of the World Cancer Research Fund criteria. Estimated cancer deaths and disability-adjusted life-years (DALYs) in 2019 and change in these measures between 2010 and 2019 are presented. Findings Globally, in 2019, the risk factors included in this analysis accounted for 4.45 million (95% uncertainty interval 4.01-4.94) deaths and 105 million (95.0-116) DALYs for both sexes combined, representing 44.4% (41.3-48.4) of all cancer deaths and 42.0% (39.1-45.6) of all DALYs. There were 2.88 million (2.60-3.18) risk-attributable cancer deaths in males (50.6% [47.8-54.1] of all male cancer deaths) and 1.58 million (1.36-1.84) risk-attributable cancer deaths in females (36.3% [32.5-41.3] of all female cancer deaths). The leading risk factors at the most detailed level globally for risk-attributable cancer deaths and DALYs in 2019 for both sexes combined were smoking, followed by alcohol use and high BMI. Risk-attributable cancer burden varied by world region and Socio-demographic Index (SDI), with smoking, unsafe sex, and alcohol use being the three leading risk factors for risk-attributable cancer DALYs in low SDI locations in 2019, whereas DALYs in high SDI locations mirrored the top three global risk factor rankings. From 2010 to 2019, global risk-attributable cancer deaths increased by 20.4% (12.6-28.4) and DALYs by 16.8% (8.8-25.0), with the greatest percentage increase in metabolic risks (34.7% [27.9-42.8] and 33.3% [25.8-42.0]). Interpretation The leading risk factors contributing to global cancer burden in 2019 were behavioural, whereas metabolic risk factors saw the largest increases between 2010 and 2019. Reducing exposure to these modifiable risk factors would decrease cancer mortality and DALY rates worldwide, and policies should be tailored appropriately to local cancer risk factor burden. Copyright (C) 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license.Peer reviewe

Qatar University Institutional Repository

Central Archive at the University of Reading

Repositório da Universidade Nova de Lisboa

shahrekord university of medical scinces

UNSWorks

Helsingin yliopiston digitaalinen arkisto

Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

Author: Abbafati Cristiana
Abbas Kaja M.
Abbasi Mohammad
Abbasi-Kangevari Mohsen
Abbasifard Mitra
Abbastabar Hedayat
Abd El Razek Hassan Magdy
Abd El Razek Muhammed Magdy
Abd-Allah Foad
Abdelalim Ahmed
Abdollahi Mohammad
Abdollahpour Ibrahim
Abdulkader Rizwan Suliankatchi
Abdullah Kanaan Hamagharib
Abedi Aidin
Abedi Parisa
Abegaz Kedir Hussein
Abolhassani Hassan
Abosetugn Akine Eshete
Aboyans Victor
Abrams Elissa M.
Abreu Lucas Guimaraes
Abrigo Michael R. M.
Abu Haimed Abdulaziz Khalid
Abu-Gharbieh Eman
Abu-Raddad Laith Jamal
Abualhasan Ahmed
Abushouk Abdelrahman I.
Acebedo Alyssa
Ackerman Ilana N.
Adabi Maryam
Adair Tim
Adamu Abdu A.
Adebayo Oladimeji M.
Adedeji Isaac Akinkunmi
Adekanmbi Victor
Adelson Jaimie D.
Adeoye Abiodun Moshood
Adetokunboh Olatunji O.
Adham Davoud
Advani Shailesh M.
Afarideh Mohsen
Afshari Mahdi
Afshin Ashkan
Agardh Emilie E.
Agarwal Gina
Agasthi Pradyumna
Agesa Kareha M.
Aghaali Mohammad
Aghamir Seyed Mohammad Kazem
Agrawal Anurag
Ahmad Tauseef
Ahmadi Alireza
Ahmadi Keivan
Ahmadi Mehdi
Ahmadieh Hamid
Ahmadpour Ehsan
Ahmed Muktar Beshir
Aji Budi
Akalu Temesgen Yihunie
Akinyemi Rufus Olusola
Akinyemiju Tomi
Akombi Blessing
Akunna Chisom Joyqueenet
Al-Aly Ziyad
Al-Mekhlafi Hesham M.
Al-Raddadi Rajaa M.
Alahdab Fares
Alam Khurshid
Alam Noore
Alam Samiah
Alam Tahiya
Alanezi Fahad Mashhour
Alanzi Turki M.
Albertson Samuel B.
Alcalde-Rabanal Jacqueline Elizabeth
Alema Niguse Meles
Alemu Biresaw Wassihun
Alemu Yihun Mulugeta
Alhabib Khalid F.
Alhassan Robert Kaba
Ali Muhammad
Ali Saqib
Alicandro Gianfranco
Alijanzadeh Mehran
Alinia Cyrus
Alipour Vahid
Alizade Hesam
Aljunid Syed Mohamed
Alla Francois
Allebeck Peter
Almadi Majid Abdulrahman Hamad
Almasi Ali
Almasi-Hashiani Amir
Almasri Nihad A.
Almulhim Abdulaziz M.
Alonso Jordi
Altirkawi Khalid A.
Alumran Arwa Khalid
Alvis-Guzman Nelson
Alvis-Zakzuk Nelson J.
Amare Azmeraw T.
Amare Bekalu
Amini Saeed
Amini-Rarani Mostafa
Aminorroaya Arya
Amiri Fatemeh
Amit Arianna Maever L.
Amugsi Dickson A.
Amul Gianna Gayle Herrera
Anbesu Etsay Woldu
Ancuceanu Robert
Anderlini Deanna
Anderson Jason A.
Andrei Catalina Liliana
Andrei Tudorel
Androudi Sofia
Angus Colin
Anjomshoa Mina
Ansari Fereshteh
Ansari Iman
Ansari-Moghaddam Alireza
Antonazzo Ippazio Cosimo
Antonio Carl Abelardo T.
Antony Catherine M.
Antriyandarti Ernoiz
Anvari Davood
Anwer Razique
Appiah Seth Christopher Yaw
Arab-Zozani Morteza
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Aravkin Aleksandr Y.
Arba Aseb Arba Kinfe
Aremu Olatunde
Ariani Filippo
Aripov Timur
Armoon Bahram
Arnlov Johan
Arowosegbe Oluwaseyi Olalekan
Aryal Krishna K.
Arzani Afsaneh
Asaad Malke
Asadi-Aliabadi Mehran
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Atteraya Madhu Sudhan
Ausloos Floriane
Ausloos Marcel
Avila-Burgos Leticia
Avokpaho Euripide Frinel Gbenato Arthur
Ayano Getinet
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Aynalem Getie Lake
Aynalem Yared Asmare
Ayza Muluken Altaye
Azari Samad
Azarian Ghasem
Azene Zelalem Nigussie
Azhar Gulrez
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Babaee Ebrahim
Badawi Alaa
Badiye Ashish D.
Bagherzadeh Mojtaba
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Bakhshaei Mohammad Hossein
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Balachandran Arun
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Balalla Shivanthi
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Biondi Antonio
Birihane Binyam Minuye
Bisanzio Donal
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Biswas Raaj Kishore
Bitew Helen
Bjorge Tone
Bockarie Moses John
Bohlouli Somayeh
Bohluli Mehdi
Bojia Hunduma Amensisa
Bolla Srinivasa Rao
Boloor Archith
Boon-Dooley Alexandra S.
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Boston Sofia
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Braithwaite Dejana
Brauer Michael
Brayne Carol
Breitborde Nicholas J. K.
Breitner Susanne
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Breusov Alexey V.
Briant Paul Svitil
Briggs Andrew M.
Briko Andrey Nikolaevich
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Britton Gabrielle B.
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Cahuana-Hurtado Lucero
Cai Tianji
Callender Charlton S. K. H.
Camera Luis Alberto
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Car Josip
Car Lorainne Tudor
Cardenas Rosario
Carreras Giulia
Carrero Juan J.
Carvalho Felix
Castaldelli-Maia Joao Mauricio
Castaneda-Orjuela Carlos A.
Castelpietra Giulio
Castle Chris D.
Castro Emma
Castro Franz
Catala-Lopez Ferran
Causey Kate
Cederroth Christopher R.
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Cerin Ester
Chalek Julian
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Chang Alex R.
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Chang Jung-Chen
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Chattu Vijay Kumar
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Chimed-Ochir Odgerel
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Chirinos-Caceres Jesus Lorenzo
Cho Daniel Youngwhan
Choi Jee-Young Jasmine
Christensen Hanne
Chu Dinh-Toi
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Ciobanu Liliana G.
Cirillo Massimo
Cislaghi Beniamino
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Collins Emma L.
Comfort Haley
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Conti Sara
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Cortesi Paolo Angelo
Costa Vera Marisa
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Cromwell Elizabeth A.
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Cruz Jessica A.
Cummins Steven
Cunningham Matthew
D'Amico Emanuele
da Silva Diana Dias
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Dai Haijiang
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Damasceno Albertino Antonio Moura
Damiani Giovanni
Dandona Lalit
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Dangel William James
Danielsson Anna-Karin
Dargan Paul I.
Darshan B. B.
Darwesh Aso Mohammad
Daryani Ahmad
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Das Neves Jose
Das Jai K.
Dash Aditya Prasad
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Davletov Kairat
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Defo Barthelemy Kuate
Degenhardt Louisa
DeLang Marissa
Dellavalle Robert Paul
Demeke Feleke Mekonnen
Demoz Gebre Teklemariam
Demsie Desalegn Getnet
Denova-Gutierrez Edgar
Dereje Nebiyu Dereje
Deribe Kebede
Dervenis Nikolaos
Desai Rupak
Desalew Assefa
Dessie Getenet Ayalew
Deuba Keshab
Dharmaratne Samath Dhamminda
Dhungana Govinda Prasad
Dianatinasab Mostafa
Diaz Daniel
Dichgans Martin
Didarloo Alireza
Dingels Zachary V.
Dippenaar Ilse N.
Dirac M. Ashworth
Djalalinia Shirin
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Dokova Klara
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Doshi Chirag P.
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Duraes Andre Rodrigues
Eagan Arielle Wilder
Ebrahimi Hedyeh
Edvardsson David
Effiong Andem
Ehrlich Joshua R.
El Nahas Nevine
El Sayed Iman
El Tantawi Maha
El-Jaafary Shaimaa I.
Elbarazi Iffat
Elgendy Islam Y.
Elhabashy Hala Rashad
Elsharkawy Aisha
Elyazar Iqbal R. F.
Emamian Mohammad Hassan
Emmons-Bell Sophia
Erskine Holly E.
Eshrati Babak
Eskandari Khalil
Eskandarieh Sharareh
Esmaeilnejad Saman
Esmaeilzadeh Firooz
Esteghamati Alireza
Esteghamati Sadaf
Estep Kara
Etemadi Arash
Etisso Atkilt Esaiyas
Ezekannagha Oluchi
Fanzo Jessica
Farag Tamer
Farahmand Mohammad
Faraj Anwar
Faraon Emerito Jose A.
Fareed Mohammad
Faridnia Roghiyeh
Farinha Carla Sofia e Sa
Farioli Andrea
Faris Pawan Sirwan
Faro Andre
Faruque Mithila
Farzadfar Farshad
Fattahi Nazir
Fazaeli Ali Akbar
Fazlzadeh Mehdi
Feigin Valery L.
Feldman Rachel
Fereshtehnejad Seyed-Mohammad
Fernandes Eduarda
Ferrara Giannina
Ferrara Pietro
Ferrari Alize J.
Ferreira Manuela L.
Feyissa Garumma Tolu
Filip Irina
Fischer Florian
Fisher James L.
Fitzgerald Ryan
Flohr Carsten
Flor Luisa Sorio
Foigt Nataliya A.
Folayan Morenike Oluwatoyin
Fomenkov Artem Alekseevich
Force Lisa M.
Fornari Carla
Forooshani Zahra Sadat Dibaji
Foroutan Masoud
Fox Jack T.
Francis Joel Msafiri
Frank Tahvi D.
Franklin Richard Charles
Freitas Marisa
Fu Weijia
Fukumoto Takeshi
Fukutaki Kai
Fuller John E.
Fullman Nancy
Furtado Joao M.
Gad Mohamed M.
Gaidhane Abhay Motiramji
Gakidou Emmanuela
Galles Natalie C.
Gallus Silvano
Gamkrelidze Amiran
Garcia-Basteiro Alberto L.
Gardner William M.
Geberemariyam Biniyam Sahiledengle
Gebrehiwot Abiyu Mekonnen
Gebremedhin Ketema Bizuwork
Gebremeskel Gebreamlak Gebremedhn
Gebremeskel Leake G.
Gebresillassie Begashaw Melaku
Gebreslassie Assefa Ayalew Ayalew Ayalew
Gela Jiregna Darega
Geramo Yilma Chisha Dea
Geremew Abraham
Gesesew Hailay Abrha
Gething Peter W.
Gezae Kebede Embaye
Ghadimi Maryam
Ghadiri Keyghobad
Ghaffarifar Fatemeh
Ghafourifard Mansour
Ghajar Alireza
Ghamari Farhad
Ghashghaee Ahmad
Ghiasvand Hesam
Ghith Nermin
Gholamian Asadollah
Ghosh Rakesh
Giampaoli Simona
Gilani Syed Amir
Gill Paramjit Singh
Gill Tiffany K.
Gillum Richard F.
Ginawi Ibrahim Abdelmageed
Ginindza Themba G.
Gitimoghaddam Mojgan
Giussani Giorgia
Glagn Mustefa
Glushkova Ekaterina Vladimirovna
Gnedovskaya Elena V.
Godinho Myron Anthony
Goharinezhad Salime
Golechha Mahaveer
Goli Srinivas
Gomez Ricardo Santiago
Gona Philimon N.
Gopalani Sameer Vali
Goren Emily
Gorini Giuseppe
Gorman Taren M.
Gottlich Harrison Chase
Goudarzi Houman
Goudarzian Amir Hossein
Goulart Alessandra C.
Goulart Barbara Niegia Garcia
Grada Ayman
Greaves Felix
Grivna Michal
Grosso Giuseppe
Gubari Mohammed Ibrahim Mohialdeen
Gudi Nachiket
Gugnani Harish Chander
Guimaraes Andre Luiz Sena
Guimaraes Rafael Alves
Guled Rashid Abdi
Gultie Teklemariam
Guo Gaorui
Guo Yuming
Gupta Rahul
Gupta Rajeev
Gupta Tarun
Haagsma Juanita A.
Hachinski Vladimir
Haddock Beatrix
Hafezi-Nejad Nima
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Hagins Hailey
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Handiso Demelash Woldeyohannes
Hanif Asif
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Hanson Sarah Wulf
Haririan Hamidreza
Haro Josep Maria
Harvey James D.
Hasaballah Ahmed I.
Hasan Md Mehedi
Hasanpoor Edris
Hasanzadeh Amir
Hashemian Maryam
Hashi Abdiwahab
Hassan Amr
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Hawariat Feleke Gebremeskel W.
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Hayat Khezar
Hayoon Anna Gershberg
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Heidari Behnam
Heidari Golnaz
Heidari-Soureshjani Reza
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Herbert Molly E.
Herrera Ana M. Mantilla
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Heydarpour Fatemeh
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Holla Ramesh
Hollingsworth Bruce
Hoogar Praveen
Hopf Kathleen Pillsbury
Horita Nobuyuki
Hosgood H. Dean
Hossain Naznin
Hosseini Mostafa
Hosseinzadeh Mehdi
Hostiuc Mihaela
Hostiuc Sorin
Househ Mowafa
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Hsieh Vivian Chia-Rong
Hu Guoqing
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Huda Tanvir M.
Hugo Fernando N.
Humayun Ayesha
Hussain Rabia
Huynh Chantal K.
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Iannucci Vincent C.
Iavicoli Ivo
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Ibitoye Segun Emmanuel
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Il Shin Jae
Ilesanmi Olayinka Stephen
Ilic Irena M.
Ilic Milena D.
Imani-Nasab Mohammad Hasan
Inbaraj Leeberk Raja
Ippolito Helen
Iqbal Usman
Irvani Seyed Sina Naghibi
Irvine Caleb Mackay Salpeter
Islam M. Mofizul
Islam MdMohaimenul
Islam Sheikh Mohammed Shariful
Islami Farhad
Iso Hiroyasu
Ivers Rebecca Q.
Iwu Chidozie C. D.
Iwu Chinwe Juliana
Iyamu Ihoghosa Osamuyi
Jaafari Jalil
Jabbari Seyed Hossein Yahyazadeh
Jacobsen Kathryn H.
Jadidi-Niaragh Farhad
Jafarabadi Mohammad Asghari
Jafari Hussain
Jafarinia Morteza
Jahagirdar Deepa
Jahani Mohammad Ali
Jahanmehr Nader
Jakovljevic Mihajlo
Jalali Amir
Jalilian Farzad
James Spencer L.
Janjani Hosna
Janodia Manthan Dilipkumar
Javaheri Tahereh
Javidnia Javad
Jayatilleke Achala Upendra
Jeemon Panniyammakal
Jenabi Ensiyeh
Jha Ravi Prakash
Jha Vivekanand
Ji John S.
Jia Peng
Johansson Lars
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John-Akinola Yetunde O.
Johnson Catherine Owens
Johnson Sarah Charlotte
Jonas Jost B.
Joo Tamas
Joshi Ankur
Joukar Farahnaz
Jozwiak Jacek Jerzy
Jurisson Mikk
Kabir Ali
Kabir Zubair
Kafil Hossein Samadi
Kalan Mohammad Ebrahimi
Kalani Hamed
Kalani Rizwan
Kalankesh Leila R.
Kalhor Rohollah
Kalhori Reza Pourmirza
Kamath Aruna M.
Kamiab Zahra
Kanchan Tanuj
Kapoor Neeti
Karanikolos Marina
Karch Andre
Karim Mohd Anisul
Karimi Salah Eddin
Karimi Seyed Asaad
Karimi Seyed M.
Karyani Ali Kazemi
Kasa Ayele Semachew
Kassa Getachew Mullu
Kassebaum Nicholas J.
Katikireddi Srinivasa Vittal
Kawakami Norito
Kayode Gbenga A.
Keddie Suzanne H.
Keiyoro Peter Njenga
Keller Cathleen
Kemmer Laura
Kendrick Parkes J.
Kereselidze Maia
Khader Yousef Saleh
Khafaie Morteza Abdullatif
Khalid Nauman
Khammarnia Mohammad
Khan Ejaz Ahmad
Khan Gulfaraz
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Yu Yong
Yuan Chun-Wei
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Zastrozhin Mikhail Sergeevich
Zewdie Kaleab Alemayehu
Zhang Jianrong
Zhang Yunquan
Zhang Zhi-Jiang
Zhao Jeff T.
Zhao Xiu-Ju George
Zhao Yingxi
Zheleva Bistra
Zheng Peng
Zhou Maigeng
Zhu Cong
Ziapour Arash
Zimsen Stephanie R. M.
Zlavog Bianca S.
Zodpey Sanjay
Publication venue
Publication date: 01/01/2020
Field of study

Background: In an era of shifting global agendas and expanded emphasis on non-communicable diseases and injuries along with communicable diseases, sound evidence on trends by cause at the national level is essential. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) provides a systematic scientific assessment of published, publicly available, and contributed data on incidence, prevalence, and mortality for a mutually exclusive and collectively exhaustive list of diseases and injuries. Methods: GBD estimates incidence, prevalence, mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs) due to 369 diseases and injuries, for two sexes, and for 204 countries and territories. Input data were extracted from censuses, household surveys, civil registration and vital statistics, disease registries, health service use, air pollution monitors, satellite imaging, disease notifications, and other sources. Cause-specific death rates and cause fractions were calculated using the Cause of Death Ensemble model and spatiotemporal Gaussian process regression. Cause-specific deaths were adjusted to match the total all-cause deaths calculated as part of the GBD population, fertility, and mortality estimates. Deaths were multiplied by standard life expectancy at each age to calculate YLLs. A Bayesian meta-regression modelling tool, DisMod-MR 2.1, was used to ensure consistency between incidence, prevalence, remission, excess mortality, and cause-specific mortality for most causes. Prevalence estimates were multiplied by disability weights for mutually exclusive sequelae of diseases and injuries to calculate YLDs. We considered results in the context of the Socio-demographic Index (SDI), a composite indicator of income per capita, years of schooling, and fertility rate in females younger than 25 years. Uncertainty intervals (UIs) were generated for every metric using the 25th and 975th ordered 1000 draw values of the posterior distribution. Findings: Global health has steadily improved over the past 30 years as measured by age-standardised DALY rates. After taking into account population growth and ageing, the absolute number of DALYs has remained stable. Since 2010, the pace of decline in global age-standardised DALY rates has accelerated in age groups younger than 50 years compared with the 1990–2010 time period, with the greatest annualised rate of decline occurring in the 0–9-year age group. Six infectious diseases were among the top ten causes of DALYs in children younger than 10 years in 2019: lower respiratory infections (ranked second), diarrhoeal diseases (third), malaria (fifth), meningitis (sixth), whooping cough (ninth), and sexually transmitted infections (which, in this age group, is fully accounted for by congenital syphilis; ranked tenth). In adolescents aged 10–24 years, three injury causes were among the top causes of DALYs: road injuries (ranked first), self-harm (third), and interpersonal violence (fifth). Five of the causes that were in the top ten for ages 10–24 years were also in the top ten in the 25–49-year age group: road injuries (ranked first), HIV/AIDS (second), low back pain (fourth), headache disorders (fifth), and depressive disorders (sixth). In 2019, ischaemic heart disease and stroke were the top-ranked causes of DALYs in both the 50–74-year and 75-years-and-older age groups. Since 1990, there has been a marked shift towards a greater proportion of burden due to YLDs from non-communicable diseases and injuries. In 2019, there were 11 countries where non-communicable disease and injury YLDs constituted more than half of all disease burden. Decreases in age-standardised DALY rates have accelerated over the past decade in countries at the lower end of the SDI range, while improvements have started to stagnate or even reverse in countries with higher SDI. Interpretation: As disability becomes an increasingly large component of disease burden and a larger component of health expenditure, greater research and developm nt investment is needed to identify new, more effective intervention strategies. With a rapidly ageing global population, the demands on health services to deal with disabling outcomes, which increase with age, will require policy makers to anticipate these changes. The mix of universal and more geographically specific influences on health reinforces the need for regular reporting on population health in detail and by underlying cause to help decision makers to identify success stories of disease control to emulate, as well as opportunities to improve. Funding: Bill & Melinda Gates Foundation. © 2020 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licens

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Global variations in diabetes mellitus based on fasting glucose and haemogloblin A1c

Author: Abbasi-Kangevari Mohsen
Abdul Rahim Hanan F.
Abu-Rmeileh Niveen M.
Adambekov Shalkar
Adams Robert J.
Aekplakorn Wichai
Agdeppa Imelda A.
Aghazadeh-Attari Javad
Aguilar-Salinas Carlos A.
Agyemang Charles
Ahmad Noor Ani
Ahmadi Ali
Ahmadi Naser
Ahmadi Nastaran
Ahmed Soheir H.
Ajlouni Kamel
Al Asfoor Deena
Al Qaoud Nawal M.
Al-Hina Halima
Al-Lahou Badreya
Al-Lawati Jawad A.
Alarouj Monira
AlBuhairan Fadia
AlDhukair Shahla
Aldwairji Maryam A.
Ali Mohamed M.
Alinezhad Farbod
Alkandari Abdullah
Alomirah Husam F.
Aly Eman
Amarapurkar Deepak N.
Andersen Lars Bo
Anderssen Sigmund A.
Andrade Dolores S.
Anjana Ranjit Mohan
Ansari-Moghaddam Alireza
Aounallah-Skhiri Hajer
Aris Tahir
Arlappa Nimmathota
Aryal Krishna K.
Assah Felix K.
Assembekov Batyrbek
Auvinen Juha
Avdičová Mária
Azad Kishwar
Azimi-Nezhad Mohsen
Azizi Fereidoun
Bacopoulou Flora
Balakrishna Nagalla
Bamoshmoosh Mohamed
Banach Maciej
Bandosz Piotr
Banegas José R.
Bao Tran Quoc
Barbagallo Carlo M.
Barceló Alberto
Baretić Maja
Barrera Lena
Basit Abdul
Batieha Anwar M.
Batista Aline P.
Baur Louise A.
Belavendra Antonisamy
Benchekor Sounnia Mediene
Benet Mikhail
Bennett James E.
Berkinbayev Salim
Bernabe- Ortiz Antonio
Berrios Carrasola Ximena
Bettiol Heloísa
Beybey Augustin F.
Bhargava Santosh K.
Bika Lele Elysée Claude
Bikbov Mukharram M.
Bista Bihungum
Bjerregaard Peter
Bjertness Espen
Bjertness Marius B.
Björkelund Cecilia
Bloch Katia V.
Blokstra Anneke
Bo Simona
Bobak Martin
Boggia Jose G.
Bonaccio Marialaura
Bonilla-Vargas Alice
Borghs Herman
Bovet Pascal
Brajkovich Imperia
Brenner Hermann
Brewster Lizzy M.
Brian Garry R.
Briceño Yajaira
Brito Miguel
Bugge Anna
Buntinx Frank
Cabrera de León Antonio
Caixeta Roberta B.
Can Günay
Capanzana Mario V.
Capuano Eduardo
Capuano Rocco
Capuano Vincenzo
Cardoso Viviane C.
Carlsson Axel C.
Carrillo-Larco Rodrigo M.
Casanueva Felipe F.
Censi Laura
Cervantes‐Loaiza Marvin
Chamnan Parinya
Chamukuttan Snehalatha
Chan Queenie
Charchar Fadi J.
Chaturvedi Nish
Chen Huashuai
Cheraghian Bahman
Chirlaque María-Dolores
Chudek Jerzy
Cifkova Renata
Cirillo Massimo
Claessens Frank
Cohen Emmanuel
Concin Hans
Cooper Cyrus
Costanzo Simona
Cowan Melanie J.
Cowell Chris
Crujeiras Ana B.
Cruz Juan J.
Cureau Felipe V.
Cuschieri Sarah
Cândido Ana Paula C.
Dallongeville Jean
Damasceno Albertino
Danaei Goodarz
Dastgiri Saeed
Davletov Kairat
De Curtis Amalia
de Gaetano Giovanni
De Henauw Stefaan
Deepa Mohan
DeGennaro Vincent Jr
Demarest Stefaan
Dennison Elaine
Deschamps Valérie
Dhimal Meghnath
Dika Zivka
Djalalinia Shirin
Donfrancesco Chiara
Dong Guanghui
Dorobantu Maria
dos Santos Henrique Rafael
Dragano Nico
Drygas Wojciech
Du Yong
Duante Charmaine A.
Duboz Priscilla
Dushpanova Anar
Dziankowska-Zaborszczyk Elzbieta
Dörr Marcus
D’Arrigo Graziella
d’Orsi Eleonora
Ebrahimi Narges
Eddie Ricky
Eftekhar Ebrahim
Efthymiou Vasiliki
Egbagbe Eruke E.
Eghtesad Sareh
El Ati Jalila
El-Khateeb Mohammad
Eldemire-Shearer Denise
Elosua Roberto
Enang Ofem
Erasmus Rajiv T.
Erbel Raimund
Erem Cihangir
Ergor Gul
Eriksen Louise
Eriksson Johan G.
Esmaeili Ali
Evans Roger G.
Ezzati Majid
Fakhradiyev Ildar
Fall Caroline H.
Faramarzi Elnaz
Farjam Mojtaba
Farzadfar Farshad
Farzi Yosef
Fawwad Asher
Felix-Redondo Francisco J.
Ferguson Trevor S.
Fernández-Bergés Daniel
Ferrari Marika
Ferreccio Catterina
Ferreira Haroldo S.
Ferrer Eldridge
Feskens Edith J. M.
Flood David
Forsner Maria
Fosse Sandrine
Fottrell Edward F.
Fouad Heba M.
Francis Damian K.
Frontera Guillermo
Furusawa Takuro
Gaciong Zbigniew
Garnett Sarah P.
Gasull Magda
Gazzinelli Andrea
Gehring Ulrike
Ghaderi Ebrahim
Ghamari Hadi
Ghanbari Ali
Ghasemi Erfan
Gheorghe-Fronea Oana-Florentina
Ghimire Anup
Gialluisi Alessandro
Giampaoli Simona
Gianfagna Francesco
Gill Tiffany K.
Gironella Glen
Giwercman Aleksander
Goltzman David
Gomula Aleksandra
Gonzalez Angel R.
Gonzalez-Chica David A.
Gonzalez-Gross Marcela
González-Rivas Juan P.
González-Villalpando Clicerio
González-Villalpando María-Elena
Gonçalves Helen
Gonçalves Mauer
Gottrand Frederic
Grafnetter Dušan
Gregg Edward W.
Grodzicki Tomasz
Grøntved Anders
Guerrero Ramiro
Gujral Unjali P.
Gupta Rajeev
Gutierrez Laura
Gwee Xinyi
Haghshenas Rosa
Hakimi Hamid
Hambleton Ian R.
Hamzeh Behrooz
Hanekom Willem A.
Hange Dominique
Hantunen Sari
Hao Jie
Harooni Javad
Hashemi-Shahri Seyed Mohammad
Hata Jun
Heap Rachel A.
Heidemann Christin
Herrala Sauli
Herzig Karl-Heinz
Heshmat Ramin
Ho Sai Yin
Holdsworth Michelle
Homayounfar Reza
Hopman Wilma M.
Horimoto Andrea R. V. R.
Hormiga Claudia
Horta Bernardo L.
Houti Leila
Howitt Christina
Htay Thein Thein
Htet Aung Soe
Huerta José María
Huisman Martijn
Husseini Abdullatif
Huybrechts Inge
Iacoviello Licia
Iakupova Ellina M.
Iannone Anna G.
Ijoma Chinwuba
Imperatore Giuseppina
Irazola Vilma E.
Ishida Takafumi
Isiguzo Godsent C.
Islek Duygu
Ittermann Till
Iwasaki Masanori
Jacobs Jeremy M.
Jaddou Hashem Y.
Jadoul Michel
Jallow Bakary
James Kenneth
Jamil Kazi M.
Janus Edward
Jarvelin Marjo-Riitta
Jasienska Grazyna
Jelaković Ana
Jelaković Bojan
Jennings Garry
Jha Anjani Kumar
Jimenez Ramon O.
Jokelainen Jari J.
Jonas Jost B.
Joshi Pradeep
Josipović Josipa
Joukar Farahnaz
Jääskeläinen Tuija
Jóźwiak Jacek
Jöckel Karl-Heinz
Kafatos Anthony
Kajantie Eero O.
Kalmatayeva Zhanna
Karki Khem B.
Katibeh Marzieh
Kauhanen Jussi
Kazakbaeva Gyulli M.
Kaze François F.
Ke Calvin
Keinänen-Kiukaanniem Sirkka
Kelishadi Roya
Kengne Andre P.
Keramati Maryam
Kersting Mathilde
Khader Yousef Saleh
Khaledifar Arsalan
Khalili Davood
Khang Young-Ho
Kheiri Bahareh
Kheradmand Motahareh
Khosravi Alireza
Kiechl Sophia J.
Kiechl Stefan
Kiechl-Kohlendorfer Ursula
Kim Hyeon Chang
Kingston Andrew
Klakk Heidi
Klanova Jana
Knoflach Michael
Kolsteren Patrick
Korpelainen Raija
Korrovits Paul
Kos Jelena
Koskinen Seppo
Kowlessur Sudhir
Koziel Slawomir
Kriemler Susi
Kromhout Daan
Kubinova Ruzena
Kujala Urho M.
Kulimbet Mukhtar
Kumar Rachakulla Hari
Kurjata Pawel
Kyobutungi Catherine
König Jürgen
Laatikainen Tiina
Labadarios Demetre
Lachat Carl
Laid Youcef
Lall Lachmie
Lankila Tiina
Lanska Vera
Lappas Georg
Larijani Bagher
Latt Tint Swe
Laurenzi Martino
Laxmaiah Avula
Lehmann Nils
Lehtimäki Terho
Lemogoum Daniel
Leung Gabriel M.
Lhoste Victor
Li Yanping
Lima-Costa M. Fernanda
Lin Hsien-Ho
Lind Lars
Lissner Lauren
Liu Xiaotian
Lopez Tania
Lopez-Garcia Esther
Lozano José Eugenio
Lu Yuan
Luksiene Dalia
Lund Kristensen Peter
Lundqvist Annamari
Lunet Nuno
Lustigová Michala
Machado-Coelho George L. L.
Machado-Rodrigues Aristides M.
Macia Enguerran
Macieira Luisa M.
Madar Ahmed A.
Maestre Gladys E.
Maggi Stefania
Magliano Dianna J.
Magriplis Emmanuella
Mahasampath Gowri
Maire Bernard
Makdisse Marcia
Malekpour Mohammad-Reza
Malekzadeh Fatemeh
Malekzadeh Reza
Malyutina Sofia
Maniego Lynell V.
Manios Yannis
Mannix Masimango Imani
Mansour-Ghanaei Fariborz
Manzato Enzo
Margozzini Paula
Mariño Joany
Martorell Reynaldo
Mascarenhas Luis P.
Masinaei Masoud
Mathiesen Ellisiv B.
Matsha Tandi E.
Mbanya Jean Claude N
McDonald Posso Anselmo J.
McFarlane Shelly R.
McGarvey Stephen T.
Mehlig Kirsten
Mehrparvar Amir Houshang
Melgarejo Jesus D.
Menezes Ana Maria B.
Mereke Alibek
Meshram Indrapal I.
Meto Diane T.
Minderico Cláudia S.
Mini G. K.
Miquel Juan Francisco
Miranda Jaime
Mirjalili Mohammad Reza
Mishra Anu
Modesti Pietro A.
Moghaddam Sahar Saeedi
Mohamed Mostafa K.
Mohammad Kazem
Mohammadi Mohammad Reza
Mohammadi Zahra
Mohammadifard Noushin
Mohammadpourhodki Reza
Mohan Viswanathan
Mohd Yusoff Muhammad Fadhli
Mohebbi Iraj
Molnár Dénes
Momenan Amirabbas
Mondo Charles K.
Montenegro Mendoza Roger A.
Monterrubio-Flores Eric
Moosazadeh Mahmood
Moradpour Farhad
Morejon Alain
Moreno Luis A.
Morgan Karen
Morin Suzanne N.
Moslem Alireza
Mosquera Mildrey
Mossakowska Malgorzata
Mostafa Aya
Mostafavi Seyed-Ali
Motlagh Mohammad Esmaeel
Motta Jorge
Msyamboza Kelias P.
Mu Thet Thet
Muiesan Maria L.
Mursu Jaakko
Musa Kamarul Imran
Mustafa Norlaila
Muyer Muel Telo M. C.
Méndez Fabián
Møller Niels C.
Nabipour Iraj
Nagel Gabriele
Naidu Balkish M.
Najafi Farid
Nangia Vinay B.
Naseri Take
NCD Risk Factor Collaboration (NCD-RisC)
Neelapaichit Nareemarn
Nejatizadeh Azim
Nenko Ilona
Nervi Flavio
Ng Tze Pin
Ngoc La Quang
Nguyen Chung T.
Nguyen Quang Ngoc
Ni Michael Y.
Nie Peng
Nieto-Martínez Ramfis E.
Ninomiya Toshiharu
Noale Marianna
Noboa Oscar A.
Noto Davide
Nsour Mohannad Al
Nuhoğlu Irfan
Námešná Jana
Odili Augustine N.
Oh Kyungwon
Ohtsuka Ryutaro
Omar Mohd Azahadi
Onat Altan
Ong Sok King
Onodugo Obinna
Ordunez Pedro
Ornelas Rui
Ortiz Pedro J.
Osmond Clive
Ostovar Afshin
Otero Johanna A.
Ottendahl Charlotte
Otu Akaninyene
Owusu-Dabo Ellis
O’Neill Terence W.
Paciorek Chris J.
Palmieri Luigi
Pan Wen- Harn
Panda-Jonas Songhomitra
Panza Francesco
Paoli Mariela
Park Suyeon
Parsaeian Mahboubeh
Patel Nikhil D.
Pavkov Meda E.
Pechlaner Raimund
Pedro João M.
Peltonen Markku
Pereira Alexandre C.
Pessôa dos Prazeres Thaliane Mayara
Peykari Niloofar
Pećin Ivan
Phall Modou Cheyassin
Pham Son Thai
Phan Hiep Hoang
Phelps Nowell H.
Pichardo Rafael N.
Pikhart Hynek
Pilav Aida
Piler Pavel
Pitakaka Freda
Piwonska Aleksandra
Pizarro Andreia n
Plans-Rubio Pedro
Plata Silvia
Porta Miquel
Poudyal Anil
Pourfarzi Farhad
Pourshams Akram
Poustchi Hossein
Pradeepa Rajendra
Providencia Rui
Pruner Marques Larissa
Puder Jardena J.
Puhakka Solie
Punab Margus
Qorbani Mostafa
Quintana Hedley K.
Rahimikazerooni Salar
Raitakari Olli
Ramachandran Ambady
Ramirez Manuel
Ramke Jacqueline
Ramos Rafel
Rampal Lekhraj
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Rao Kodavanti Mallikharjuna
Rashidi Mohammad-Mahdi
Rayner Archie W.
Redon Josep
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Reza Fattahi Mohammad
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Rigo Fernando
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Robinson Louise
Rodriguez-Perez María del Cristo
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Schmidt Carsten O.
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Slusarczyk Przemysław
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Somi Mohammad Hossein
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Tuomainen Tomi-Pekka
Tzala Evangelia
Tzourio Christophe
Ueda Peter
Ugel Eunice
Ukoli Flora A. M.
Ulmer Hanno
Uusitalo Hannu M. T.
Valdivia Gonzalo
van den Born Bert-Jan
Van der Heyden Johan
Van Minh Hoang
van Rossem Lenie
Van Schoor Natasja M.
van Valkengoed Irene G. M.
van Zutphen Elisabeth M.
Vander Hoorn Stephen
Vanderschueren Dirk
Vanuzzo Diego
Vasan Senthil K.
Vega Tomas
Velasquez-Melendez Gustavo
Venkat Narayan K. M.
Verstraeten Roosmarijn
Viana Peixoto Sergio
Viet Lucie
Villalpando Salvador
Vioque Jesus
Virtanen Jyrki K.
Viswanathan Bharathi
Voutilainen Ari
Wade Alisha N.
Wan Bebakar Wan Mohamad
Wan Mohamud Wan Nazaimoon
Wang Chongjian
Wang Ningli
Wang Qian
Wang Ya Xing
Wang Ying-Wei
Wannamethee S. Goya
Webster-Kerr Karen
Wedderkopp Niels
Wei Wenbin
Westbury Leo D.
Whincup Peter H.
Widhalm Kurt
Widyahening Indah S.
Wilks Rainford J.
Willeit Johann
Willeit Peter
Wilsgaard Tom
Więcek Andrzej
Wojtyniak Bogdan
Wong Andrew
Wong Emily B.
Wong Norazizah Ibrahim
Woodward Mark
Wu Frederick C.
Xu Haiquan
Xu Liang
Yaacob Nor Azwany
Yan Li
Yan Weili
Yoosefi Moein
Yoshihara Akihiro
Younger-Coleman Novie O.
Yu Yu-Ling
Yu Yunjiang
Yusoff Ahmad Faudzi
Zainuddin Ahmad A.
Zamani Farhad
Zambon Sabina
Zampelas Antonis
Zaw Ko Ko
Zdrojewski Tomasz
Zeljkovic Vrkic Tajana
Zeng Yi
Zhang Zhen-Yu
Zholdin Bekbolat
Zhou Bin
Zimmet Paul
Zitt Emanuel
Zuñiga Cisneros Julio
Čapková Naděžda
Šalaj Sanja
Publication venue: Nature Publishing Group
Publication date: 01/01/2023
Field of study

Fasting plasma glucose (FPG) and haemoglobin A1c (HbA1c) are both used to diagnose diabetes, but may identify different people as having diabetes. We used data from 117 population-based studies and quantified, in different world regions, the prevalence of diagnosed diabetes, and whether those who were previously undiagnosed and detected as having diabetes in survey screening had elevated FPG, HbA1c, or both. We developed prediction equations for estimating the probability that a person without previously diagnosed diabetes, and at a specific level of FPG, had elevated HbA1c, and vice versa. The age-standardised proportion of diabetes that was previously undiagnosed, and detected in survey screening, ranged from 30% in the high-income western region to 66% in south Asia. Among those with screen-detected diabetes with either test, the agestandardised proportion who had elevated levels of both FPG and HbA1c was 29-39% across regions; the remainder had discordant elevation of FPG or HbA1c. In most low- and middle-income regions, isolated elevated HbA1c more common than isolated elevated FPG. In these regions, the use of FPG alone may delay diabetes diagnosis and underestimate diabetes prevalence. Our prediction equations help allocate finite resources for measuring HbA1c to reduce the global gap in diabetes diagnosis and surveillance.peer-reviewe

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A. Nemer Ayoub
Abantanga Francis A.
Abatli Safa' Jamal
Abbas Wisam
Abbo Olivier
Abdelbaqi Reem
Abdelhady Dina Sobhy
Abdelhafez Mohammad Omar Mohammad
Abdelhamid Sultan S.
Abdelmaksoud Sherif
Abdelmoumen Roua
Abdelmutalib Fakereldeen
Abdul-Mumin Alhassan
Abduljawad Fatima Mousa
Abdullah Fizan
Abdullah Mohd Yusof bin
Abdulraheem Nurudeen
Abdulrahman Alaa
Abdulsalam Moruf Adekunle
Abdunomonovich Dekhkonboev Avazjon
Aboelela Ahmed
Abouheba Mohamed
Abrahamsson Kate
Abrunhosa Matias Marcia
Abu-Nejmah Fawzi
Abuajaila Abdulsalam
Abuattaya Adham Ashraf
Abubakar Auwal M
Abueideh Ahmad
Abuhayyeh Husam Aldean
Abuhlega Ma'aly A.
Abukhalaf Sadi
Abumunshar Ali Abdelhay
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Adams Stephen
Adamu Sani
Adanan Mohd Fitri Shukri bin Mohamed
Adawi Ihda
Adawi Samer
Adawy Ahmad
Ade-Ajayi Niyi
Adegboyega Rilwan
Ademuyiwa Adesoji
Adesanya Opeoluwa
Adhiwidjaja Cathline Freya
Adofo-Ansong Nana
Agboola Titiloye Hannah
Agelebe Efeturi
Aguilar Aguilar Faye
Aguilar Gargurevich Prince Pamela
Aguirre-Lopez Pastor
Agulham Miguel Angelo
Ahmad Hira
Ahmad Zahidah Adlynee Haji
Ahmed Hazem
Ahmed Mahmoud Abdelfattah
Ajai Olalekan Temitope
Ajao Emmanuel Akinlabi
Ajiboye Olalekan S.
Ajrami Yara
Ajwa Ahmad Elian Abu
Akan M. Eren
Akhbari Melika
Akhter Nadeem
Akova Fatih
Al-Attar Hala M.
Al-Halbouni Layana
Al-Mamun Abdullah
Al-Mayoof Ali Farooq
Al-Momani Hashem M.
Al-Mouakeh Ahmad
Al-Rayyes Maisara
Al-saleem Hasan Subhi Hasan Abu
Al-Salhi Ashraf Ayman
Al-Shwaikh Samar H.
Al-Slaibi Ibrahim
Al-Taher Raed Nael
Al-Taher Raed Nael
Al-Tammam Hiba
Alakaloko Felix
Alamrain Abdulwhhab Ayman Abu
Alanguia Chipana Cathy Lee
Alattas Khalid
Alberto Carlos
Albozidi Aya
Alcántara Elvyn
ALDIRAWI MOHAMMED A. M.
Alebbini Mohanad Mutasem
Alfoghi Mabroka
Algabri Hayder Nadhim Obaid
Alglaib Mohammed Meftah
Alhamid Ahmad
Alhamid Aos
Alhassan Priscilla
Ali Hassan
Ali Karim Osamy
Ali Liza
Ali Mansour
Alijla Sharif
Alijla Sharif S.
Aliwisat Ahmad Hasan
Aljaboo Hajir
Aljadidi Wesal Omar F. Saied
Aljarad Ziad
Alkareem Raghad mohammad abdu
Almada Suad Ahmed
Almadhoun Walaa
Almasri Murad
Almeida Aguiar Arthur
Almeida Giovana
Almengar Inas
Almohamady Hisham
Almosaibli Mohammad
Almusleh Tasneem Fathi Hasan
Alnaeri Ali
Alnahhal Khaled
Alonso Verónica
Alosta Hasan Mustafa
Alqarajeh Firas
Alqor Mohammad Omar Ibrahim
Alsaadi Nijmeh Nasser
Alsaggaf Ameen
Alsaied Amer
Alser Mohammed
Alser Osaid H.
Alshaikhkhalil Haya Abdulnasser Ali
Alshehri Abdullah
Altaweel Ahmed
Altın Merve
Altokhais Tariq
Altomi Mohamed
Alturki Fahad
Alvarado Zelada Jackelyne
Alves Dutra da Silva Érika
Alwadia Soha Marwan Salem
Alwaggaa Nouriyah Ali
Alzamari Ainaa Ata Mohammad
Alzate Gallego Edgar
Alzeer Asmahan Mohammad Suliman
Alzerei Sulaiman T.
Alzraikat Sayel H.
Alzubair Afnan
Alzughayyar Tareq Z.
Amad Mohamed
Amado Fernando
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Amarin Justin Z.
Amarin Marzouq
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Ameh Emmanuel
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Amoabin Afua Amoabin
Anatole Nzanzu
Anatole Nzanzu Kipata
Anaya Dominguez Marlene
Anaya Firas
Andrade Jerhy
Andreussi Lorna
Anicama Elias Rocio
Annajjar Mohammad hasan
Anntinea Jessmine
Antunes Amanda
Antunez-Mora Alexandra
Anyomih Theophilus Teddy Kojo
Anzelewicz Stefan
Apaza Leon Jose Luis
Appeadu-Mensah William
Arabiat Esraa
Arafa Mohamed Ahmed
Arafat Hasan
Aragão Liliana
Arancibia Gutiérrez Elsa
Aranda Sánchez Cristian Irela
Arar Ahmad Samih
Arauco Jenny
Arbab Hana
Arboleda Jenny
Aremo Anuoluwapo
Arnadóttir Helena
Arnaud Alexis P
Arnold Marion
Arnoletto Lucia Beatriz
Arrmali Saddam
Arrmalli Lina Ali
Arshad Muhammad
Arthur Felicity
Arul Suren
Ashour Dina Ayman
Ashour Yara shareef
Aslan Yakup
Aspirot Ann
Assi Ahmadfateh
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Astudillo Miguel
Atatri Yazid yousef mahmoud
Atta Ahmed
Attia Alaa Mobarak
Avile Romina
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Awad Hadeel
Aydin Emrah
Aykut Merve
Ayque Rosas Fernando
Aziz Dayang Anita Abdul
Ba'baa' Basheer
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Baistrocchi Valentina
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Balousha Abrar ghassan
Bamanga Ahmed
Baniowda Muath A. M.
Bao Xiaozhou
Barauskas Vidmantas
Barbosa Patricia Reis
Baseggio Natalia
Bashir Fatma
Bashir Muhammad Kashif
Bassan Gonçalves Paulo César
Bataineh Ziad A.
Batal Mohammad Mohannad
Bazozi Hana Milad
Beasley Spencer
Becker Karin
Belmino Gadelha Aluísio Augusto
Benaskeur Yousra-Imane
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Berrocal Anaya Waldo
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Blain Otilia Eva
Blanc Thomas
Blazquez-Gomez Eva
Bobadilla Morales Lucina
Bode Christopher
Bonnard Arnaud
Boonthai Ampaipan
Borbonet Daniel
Bouhadiba Nordeen
Bowder Alex
Bracho Blanchet Eduardo
Bradshaw Kate
Bragagnini Paolo
Brahmamdam Pavan
Bravo Mauro Nicolas
Bright Benedict Paul
Brito Quevedo Luz Mery
Broch Aline
Brolin Santis Isolan Paola Maria
Brunero Marco
Bruxel Carla Luisa
Bsisu Isam
Bucaram Elena
Bueno Mazzuca Rafael
Bueno Motter Sarah
Bujarimin Ahmad Shafiee bin
Bulnes Mendizabal David
Burks Stephen S.
Burns Kate
Butler Marilyn
Bvulani Bruce
C. Nwosu David
Caamal Lorenzo Juvencio
Calancea Calin
Calderon Moore Antonio
Calderón Arancibia José Alfredo
Calistus Nwachukwu
Cama Jitoko
Camamra Kajali
Cameron Fraser
Camp Lauren
Canözer Ali
Caouette-Laberge Louise
Cardenas Alva Loreley Raquel
Cardenas Ruiz Velasco Juan Jose
Carrasco Ana Lucia
Carrasco-Ortega Cesar
Carrillo Isabel
Casado Francis Tanise
Casal Beloy Isabel
Caseb Paloma
Casquero Victor
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Castaño Avila Daniela
Castedo Camacho Fabiola Ruth
Cavaiuolo Silvia
Cañapataña Sahuanay Veronica Raquel
Cepeda Rodrigo
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Chan Jonathan
Chang Jeremy
Charras Maria Delia
Chaudary Ali Raza
Chaudhry Muhammad Amjad
Chauhan Nirav
Chavez Galvez Patricia
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Chen Rui
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Chipalavela Rossana Francisco
Chiriboga Elena
Chitiavi Soita Wycliffe
Chitnis Milind
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Choo Candy SC
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Chukwuemeka Anyanwu Lofty-John
Chung Jae Hee
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Corona C. Rivera Jorge Román
Corona Rivera Alfredo
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Correa Armandou
Correa Catalina
Corrêa Costa Eduardo
Cosoreanu Vlad
Costas-Chavarri Ainhoa
Cripovich Alejandrina
Cunningham Aaron
Czauderna Piotr
Cáceres Aucatoma Freud
Cárdenas Barón José de Jesús
Cömert Hatice Sonay Yalçın
da Silva Augusto Maria Lucia
Dagilytė Rūta
Dahman Nesrine Ben Hadj
Dajia Wang
Dalek Noor Fa'izatul Rahil Ambok
Dallegre Maria Belen
Dalloul Hisham
Damiani Andrea
Dammagh Nagham Mohammed Al
Dania Bouguermouh
Darras Osama Majed
Darwish Ahmed S
Darwish Ammar
Dass Anthony
Dassonville Martine
Davenport Kate
David Kuria
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Davis Jenna Kylene
de Assis Silva Murilo
de Azevedo Belesa Flavia
de Campos Vieira Abib Simone
de Deus Passos Leles Kamila
de Guzman Johann
de Souza Santos Ferreira Mariana
Dedeke Florence
Defago Victor Hugo
Defert Coralie
Delefortrie Thomas
Delforge Xavier
Delft Dirk von
Delgado Malaga Florangel Patricia
Delgado Quinteros Edgar Fernando
Dellenmark Blom Michaela
Dendusic Nejra
Derbew Miliard
Derks Terry
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Di Siervi Oscar
Diaz Castañeda Flor de Maria
Diaz Echegaray Marlene
Diaz Gomez Jose Manuel
Diaz Leon Cesar
Dieudonné Lemfuka
Dimatatac Doris Mae
Djordjevic Ivona
Dogar Sohail
Doheim Mohamed Fahmy
Dominguez Danny
Donglai Hu
Dornellas do Nascimento Suely
dos Santos Dias André Iván Bradley
Dosselman Luke J.
Douiri Abdel
Drah Weam
Dube Andile Maqhawe
Duchesne Camille
Duggan Eileen
Duote Cai
Dure Carolina
Dávila Perez Roberto
Ebeido Annan
Egbuchulem Ifeanyichukwu Kelvin
Ejinkeonye Eze Chukwuemeka
Ekenze Sebastian Okwuchukwu
Ekwunife Okechukwu Hyginus
El-Ghazaly Mohammed
Elassall Gena Mohamed Hamed
Elayeb Abdallah
Elebute Olumide Abiodun
Elewaily Mohamed
Elfiky Mahmoud
Elgammudi Mala
Elghazaly Shrouk Mahmoud
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Elhadi Muhammed
Elhajjaji Yasmine Ali
Elhattab Ahmad
Elisante Joseph
Elkaloush Abdullahn Abdousalam
Elkhazmi Ebtesam Othman Abdulsalam
Elmenam Mohamed Abd
Elmzyyen Aya Mahmoud
Elrais Safa Abdal
Elsadek Menan Ahmed
Elsaied Adham
Elshaer Omar Adly
Elsherbiny Mohamed
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Elstad Maria
Elzohiri Mohamed
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Emil Sherif
Enbaya Manal Ben
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Erdem Melisa
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Essa Tarek Mohamed
Essamilghi Kamila Almabrouk Mohammed
Ezidiegwu Ugochukwu S
Ezomike Uchechukwu Obiora
Faboya Omolara Moronkeji
Fachin Camila
Fadhle Muhamed Jassim
Faks Vivian
Falah Eyad Hassan
Farag Eman mohamed
Fares Jehad
Farha Mervat Sufian Abu
Farion-Aguiar Luiz
Fawzy Omar Moustafa
Fayez Mohamed
Fazli Mohamad Rafi
Feldens Leticia
Felix Michael
Ferdousi Tamanna
Fernandes de Oliveira Darli
Fernandes de Souza Rachel
Fernandez Ferrer Marianelly
Fernandez Portilla Emilio
Fernandez Wilson Miriam Daniela
Ferraz Schopf Luciano
Flores Carbajal Lenny
Ford Kat
Forero Ladino Angelica Maria
Fouda Mohamed Fayez
Fouly Mariam Albatoul Nageh
Fouquet-Languillat Virginie
Fourcade Laurent
Fowler Kathryn L
Fox Sarah
Franco Helena
Furtado Meyer Karine
Furtado Mariana
Féliz Erick
Gabriel Comba
Gad Dalia
Gadepalli Samir
Gai A.
Galdeano Marcelo
Gall Caroline Le
Gamage Tharanga
Gamboa Kcomt Segundo
Gao Zhigang
Gao Zhou Chong
Garcia Martinez Humberto
Garcia Isidora
Garcia Virginia
Garcia-Aparicio Luis
García Miriam
Gargum Sondas Ali
Garnier Hanna
Garrett-Cox Robin
Gasana Georges
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Gavrila Bogdan
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Gee Oliver
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Ghallab Alaa
Ghaly Khaled Abd elrahman
Ghanem Waleed H.
Ghayth Sumayyah
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Ghilardi Silva Ximena
Ghorab Islam Abdelmonem
Ghosh Dhruv
Gilardi Jose
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Goddard Lucy
Goebel Peter
Gohil Hetal
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Gomez Juanita
Gomez Oscar
Gondal Mudassir Fayaz
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Gonzalez Cortez Luis Fernando
Gonzalez Daniel Emilio
Gonzalez Joann
González Ojeda Alejandro
Gonçalves Borges Carolina
Gonçalves da Cunha
Gonçalves Victor
Gosain Ankush
Grabowski Andrzej
Granéli Christina
Greenberg Jodie
Grella Maria Giovanna
Grosos Céline
Grottling Emma
Grynberg Lucie
Guadagno Elena
Guayelema Marisol
Guazzotti Marinella
Guerin Florent
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Guinsburg Ruth
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Habiba Alouani
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Hagander Lars
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Haider Naveed
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Halabi Yasmeen Adly
Hall Nigel
Hall Timothy
Hameed Soban
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Hamill James
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Hammond Philip
Hammouri Ahmad G.
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Han Yijiang
Hanifah Nur Atiqah binti Mohd
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Harilal Shamaman
Harper Luke
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Hashim Imran
Hashim Sophia
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Hassan Mohamed Abada
Hassan Mohd Razin bin
Hassan Zulfitri bin Md
Herappe Mellado Dorihela
Herdan Mohamed Omar
Hernández Córdova Karina
Herrera Pesara Luciana Martina
Herrera Carina
Herrera Laura
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Hinostroza Daniel
Hisham Intisar
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Hussein Sara Al
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Hyman Gabriella
Ibarra Daniel
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Ibrahim Mahmoud abdelshakour
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Ionescu Sebastian
Iracelay Susana
Iriondo Martí
Ishak Shareena
Ismail Enas Musa
Ismavel Vijay Anand
Itangishaka Innocent
Ivanov Monica
Jabaiti Mohammad S.
Jabang John N.
Jaber Dania
Jacobson Jillian
Jain Sunil
Jaiteh Musa
Jallow Cherno S.
Jalo Iliya
Jamal Muhammad Umer
Jamie Najlaa Abu
Jamie Yasmin Mohammed Khalil Abu
Jaramillo Martha
Jauri Cesar
Jayaratnam Sridharan
Jayyab Mustafa abu
Jester Ingo
Jimenez Morejon Vinicio
Joda Ali Egab
Joharifard Shahrzad
Johnson Stephanie
Jones Brendan
Jones Ceri
Jones Matthew
Jonuzi Asmir
Jooma Uzair
Joubeh Sharehan
Jovcheski Laze
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Julio Lapalma
Junes Maria del Carmen
Junjie Chen
Junyi Wang
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Jyun Keily Wong Yue
Jáuregui Lorena
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Kader Şebnem
Kalicińsk Piotr
Kamel Tarek mohamed
Kamilovski Marjan
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Kano Yar
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Karabulut Ramazan
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Karamustafic Azra
Karavdic Kenan
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Karim Safina
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Kayed Yara Imad Omar
Kayibanda Emmanuel
Kchiche Nahla
Kelay Arun
Keleş Elif
Keshtgar Alireza
Khaled Ala
Khalel Wegden ibrahim almabrouk
Khalid Hazlina Mohd.
Khamag Omar
Khatatba Lara Zahi Adel
Khattak Muhammad Adnan Khan
Khlevner Julie
Khodor Cury Edson
Khorana Jiraporn
Kihiko David
Kim Hyun-Young
King Sebastian
Knorr Brenner Nicole
Knorr Christian
Knurowska Agata
Kohaut Jules
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Kostic Ana
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Krayem Yousef
Krisanova Dasha
Krishnaswami Sanjay
Kufeji Dorothy
Kukkady Askar
Kumar Vijay
Kumolalo Felix O.
Kunfah Sheba Mary Pognaa
Kurian Merina
Kurt Gökmen
Kwasau Henang
Laberge Jean-Martin
Labonia Carla
Ladipo-Ajayi Oluwaseun
Lahlooh Raghad abdullateef
Lakhoo Kokila
Lander Tony
Landivar Cino Enrique
Langer Monica
Langley Jason
Lapouble Francisco
Lara Sandra
Laraqui Hossini Samia
Latiff Zarina Abdul
Lawal Taiwo
Lawalbarau Abdullahi
Layas Tesneem
Laymouna Moustafa A.
Leal Paola Osses
Leather Andrew J. M.
Lechmiannandan Abhirrami
Ledesma Peraza Jesmarina
Lee Ju yeon
Lee Sanghoon
Leech Mary
Lerma Sergio
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Levitt Marc
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León Frutos Francisco Javier
Li Haijing
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Liang Liang
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Lim Felicia
Lin Nicole
Lindert Judith
Lino Urquizo Marcelo Mauricio
Liu Yang
Liubsys Arunas
Liukitithara Sirima
Ljuhar Damir
Llap Unchón Genaro
Lobos Pablo
Lodhia Jay
Loo Neyra Maria Susana
Lopes de Almeida Thayná
Lopes Teixeira Ferdinando Danielle
Losa Gabriela Natalia
Losty Paul
Lotfollahzadeh Saran
Loyola Ferreira Julia
Lu Jinjing
Lubbad Walaa
Lucio Palazzi
Lui Yang
Lukac Marija
Lule Joseph
Luo Wenjuan
Lv Junying
Lv Zhibao
Lyttle Bailey D.
Løfberg Katrine
M. Ballah Abubakar
M. Qabaja Mahmoud
Mac Carlos
Macdonald Alex
Machemedze Solomon
Madieh Jomana
Madziba Sanele
Mahmoud Ahmed Mokhtar
Mahmud Khalid
Mahmud Refoyez
Mairami Amsa B.
Maistry Niveshni
Makhmud Aliev
Malcius Dalius
Malik Janan
Malik Sawazen
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Mangray Hansraj
Manirambona Emery
Manjira Emmanuel
Manni Francesco
Mansfield Sara
Mansour Islam
Mansour Mohamed Awad
Marcos Dolores
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Marmol Monica
Marta Osowicka
Martin Aranda Diego
Martin Benjamin
Martinez-Leo Bruno
Martins Bianca M. R.
Martínez Hernández Magro Nestor
Mary Koshy Roshine
Massry Nasrallah Ashraf Al
Matour Bashar M.
Mayaleh Abdelrazzaq Abu
Mbonicura Jean Claude
Mbonisweni Akhona
Mccluney Simon
McColl Makepeace Lydia
Medard Pablo
Meftah Asma
Melo Gallindo Rodrigo
Meloche-Dumas Léamarie
Mena Adriana
Mendez Benavente Carolina
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Mendoza Leon Nancy Rossana
Mendoza Oviedo Juan Jose
Menin Flavio Augusto
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Mert Mustafa Kurthan
Merwe Elmarie vd
Mesas Burgos Carmen
Mesic Amira
Michael Vishal
Middlesworth William
Middleton Thomas
Mieres Carlos
Mikneviciute Agne
Milisic Emir
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Miriam Ann
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Misk Rami Anwar
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Mitul Ashrarur Rahman
Modekwe Victor
Modi Varun
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Mohammed Abobaker
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Mohammed Hanan Mahmoud
Mohammed Mansour Mkayed
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Moitt Natalie
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Molina Marcelo
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Monawar Abdul Baqi
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Montoya Debora
Mora Maria
Moraes Mario
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Moreno Maria Eugenia
Moriya Eliane
Morjan Mohammed
Mose Moraa
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Motter Sarah Bueno
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Mouttalib Sofia
Mshelbwala Philip Mari
Msuya David
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Mugo Robert
Muhic Amila
Mulu Jack
Mumtaz Uzma
Muntean Liviu
Murad Amir M. I.
Muradi Teymursha
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Muraveji Qais
Murillo Ericka
Murshidi Raghad M.
Murtadi Habib Mansour
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Muslimovich Aliev Makhmudjan
Mussein Haidar Mohammad
Mustufa Hamassat
Mutlu Mehmet
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Mvukiyehe Jean Paul
Mwai Timothy
Nageh Mohammad
Nah Shireen Anne
Naidoo Rasika
Naim Nur Atifah binti Mohd
Naim Samy Rafat Ramadan
Naranjo Kelly
Nassar Ismail
Nataraja Ramesh M
Naumeri Fatima
Naunova Vesna Cvetanovska
Ndata Albert
Ndayishimiye Isaac
Ndungu James
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Negida Ahmed
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O'Connor Zachary
Obianyo Nene Elsie
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Ochieng Roseline
Odi Abd Al-Naser Bany
Ogundoyin Olakayode
Olabisi Osagie O
Olanrewaju Moses
Olayade Kayode
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Oliveira de Andrade Susy
Oliveira Danielle Paula de
Olivos Perez Maricarmen
Olori Samson
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Omari Rand Y.
Omendo Liyenzero Polycarp
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Ormeño Calderón Luis
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Osagie Olabisi
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Oshiba Ahmed Mohamed
Osman Marjmin
Osorio Fory Ghordana
Osowicka Marta
Osuigwe Andrew N
Osuoji Roland Iheanyichukwu
Othman Mohd Yusran Bin
Otuneye Adekunle T.
Outani Oumaima
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Owusu Sheila
Owusu-Sekyere Frank
Oyebanji Lateef
Oyinloye Adewale
Ozen Mehmet Ali
Pachl Max
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Pasierbek Michal
Pasqua Noemi
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Patkowski Dariusz
Patzer Ludwig
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Paz Soldan Carolina
Pernik Mark N.
Peycelon Matthieu
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Riboni Cristiana
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Rincon Luis Carlos
Rios Flores Izabel Maryalexandra
Rissmann Anke
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Rivera Altamirano Porfirio
Rivera Alvarez Julio
Roberts Charles A.
Roberts Kiera
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Roszkiewicz Anna
Ruan Weiwei
Rudolfson Niclas
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Ruzgar Nensi
Rygl Michal
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Saad Mahmoud M.
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Sharabati Fadwa
Sharabati Mutassem
Sharif Muhammad
Sharif Randa Alamen M
Shaw Kenneth
Shehada Mohammed
Shehu Ibrahim
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Sherer Karen
Sherzad Ajmal
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Shnishah Aya Essam
Shokri Hajer Ali
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Shoubaki Ali
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Siddiqui Sabina M
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Simon Soledad
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Singer Georg
Singh Michael
Sivaraj Jayaram
Sivasubramaniam Mithila
Siyotula Thozama
Slavkovi Andjelka
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Smith Emily Rose
Soares de Fraga José Carlos
Sobrero Helena
Soccorso Giampiero
Sokolovic Emir
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Solanki Meghna
Soliman Nourhan Akram
Son Joonhyuk
Song Eung song
Soomro Aqil
Sotelo Sanchez Jennifer
Souhem Touabti
Soula Enas
Souza Barros Beatriz
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Sowe Babucarr
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St-Louis Etienne
St-Vil Dickens
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Suradi Haya H.
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Suzen Alev
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Swessi Hisham
Syed Shahnoor
Syovata Francisa
Szklarz Maria Tatiana
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Sönmez Kaan
T Shajin
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Tababa Osama
Tabari Ahmad Khaleghnejad
Tabiri Stephen
Tadesse Amezene
Tahyneh Abdulraheem Adnan Abdulraheem
Takrouney Mohammed Hamada
Talat Nabila
Tallaa Mohamed Anwer El
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Tamaddun Hafatin Fairos bt
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Tanimola Adebayo Gbenga
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Tarabishi Ahmad Sankari
Tarek Ahmed
Tarmohamed Murad
Tarniba Sara Ali
Tarrado Xavier
Tasker David
Teague Warwick
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Teo Rufinah
Teran Araceli
Terzic Sabina
Testoni Daniela
Thaiwatcharamas Kanokrat
Thiessen Jesh
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Thomas Gordon
Thomas Mark C
Thompson Hannah
Till Holger
Tillig Bernd
Tinoco Guzmán Nestor Julien
Tobor Szymon
Toczewski Krystian
Tom Alan
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Torres Picón Cintya Maria de Jesus
Torres-Canchala Laura
Toselli Luzia
Touabti Souhem
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Tovar Gutierrez Natalia
Trainba Sara
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Trindade Deyl Rafael
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Trypens Agata
Tumi Mohamed
Tuyishime Eugene
Türkyılmaz Canan
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Ubhi Harmony
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Ugwunne Chuka A
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Ullrich Sarah
Vacek Jonathan
Vaitkiene Agota
Valencia Santiago
Valeria Pelussi
Valerio-Vazquez Rafael
Vanis Nedim
Vaquila Justo
Varela Maria Florencia
Vasquez Matos Juan Pedro
Vatta Fabrizio
Vega Centen Stephany
Velaña Junior
Vellusamy V Muthualhagi M
Venant Ntakarutimana
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Verdeata Roxana
Verduga Ivan
Verduga Leonardo
Vergara Carolina
Verkauskas Gilvydas
Veronica Sofficci
Vervoort Dominique
Vianney Butoyi Jean Marie
Vida Lucian
Vidal Cristian R. Zalles
Vierboom Liam
Villalba Villalba Araceli
Villegas Silva Raúl
Vinskaite Asta
Vos Corné de
Vosoughi Armin
Wafa Tamer
Walker Gregor
Wang Jinhu
Wang Peng
Waseem Basma
Weeratunga Naveen
Weiszewsk Alicja
Wen Gang
Werneck Raposo Juliana
Wester Tomas
Wijekoon Naveen
Wilke Alexandra
Williams Isabelle
Williams Omolara
Williams Regan
Win Win Sabai Phyu
Wishah Bisan D. M.
Wishah Nidal
Wissanji Hussein
Wolak Przemyslaw
Wolny Agnieszka
Wong Janice
Wong Marilyn
Wright Naomi Jane
Wu Guowei
Wyrzykowski Dariusz
Xiaodong Guo
Xie Hua
Yacoub Mina A.
Yaghi Bashar
Yaghi Dua Hasan
Yalcinkaya Ali
Yang Hee-Beom
Yanis Ahmad H.
Yanowsky Reyes Guillermo
Yao Yang
Yapo Benjamin
Yarza Fernández Jessica
Yeniay Aslı Öztürk
Yola Mariya Mukhtar
Yong Feng
Youn Joong Kee
Yousuf Hina
Yu Mengnan
Yu Raisa
Yuen Quah Soong
Yuldashev Rustam Z.
Yunus Aayenah
Za'nouneh Faris J. Abu
Zaghlol Louay Y.
Zahari Dato' Dr Zakaria bin
Zain Mostafa
Zaman Azrina SK
Zanellato Josiane Bernartt
Zarwawi Ahmad Zulhisyam bin
Zea-Salazar Luis Enrique
Zeinelabdeen Ali
Zhao Xiaoxia
Zhu Jianming
Zhu Libin
Zidan Mazen
Zivanovic Dragoljub
Zottis Barcelos Fabricio
Zreeg Dafer abdulhakim . S.
Zurikat Rajai O.
Zvizdic Nada
Zvizdic Zlatan
Çekiç Bahanur
Çelik Müge
Özçelik Zerrin
Şeref Kıvanç
Šafus Antonín
Škvařil Jan
Štichhauer Radek
Publication venue: 'Elsevier BV'
Publication date: 01/01/2021
Field of study

Summary Background Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income countries globally, and identified factors associated with mortality. Methods We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis, exomphalos, anorectal malformation, and Hirschsprung’s disease. Recruitment was of consecutive patients for a minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause, in-hospital mortality for all conditions combined and each condition individually, stratified by country income status. We did a complete case analysis. Findings We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal malformation, and 517 with Hirschsprung’s disease) from 264 hospitals (89 in high-income countries, 166 in middleincome countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male. Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3). Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups). Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in lowincome countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries; p≤0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88–4·11], p<0·0001; middle-income vs high-income countries, 2·11 [1·59–2·79], p<0·0001), sepsis at presentation (1·20 [1·04–1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention (ASA 4–5 vs ASA 1–2, 1·82 [1·40–2·35], p<0·0001; ASA 3 vs ASA 1–2, 1·58, [1·30–1·92], p<0·0001]), surgical safety checklist not used (1·39 [1·02–1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed (ventilation 1·96, [1·41–2·71], p=0·0001; parenteral nutrition 1·35, [1·05–1·74], p=0·018). Administration of parenteral nutrition (0·61, [0·47–0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65 [0·50–0·86], p=0·0024) or percutaneous central line (0·69 [0·48–1·00], p=0·049) were associated with lower mortality. Interpretation Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between lowincome, middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger than 5 years by 2030

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Fareed Mohammad
Farinha Carla Sofia e Sá
Faris MoezAlIslam Ezzat Mahmoud
Faris Pawan Sirwan
Faro Andre
Fasanmi Abidemi Omolara
Fatehizadeh Ali
Fattahi Hamed
Fauk Nelsensius Klau
Fazeli Pooria
Feigin Valery L
Feizkhah Alireza
Fekadu Ginenus
Feng Xiaoru
Fereshtehnejad Seyed-Mohammad
Feroze Abdullah Hamid
Ferrante Daniela
Ferrari Alize J
Ferreira Nuno
Fetensa Getahun
Feyisa Bikila Regassa
Filip Irina
Fischer Florian
Flavel Joanne
Flood David
Florin Bobirca Teodor
Foigt Nataliya A
Folayan Morenike Oluwatoyin
Fomenkov Artem Alekseevich
Foroutan Behzad
Foroutan Masoud
Forthun Ingeborg
Fortuna Daniela
Foschi Matteo
Fowobaje Kayode Raphael
Francis Kate Louise
Franklin Richard Charles
Freitas Alberto
Friedman Joseph
Friedman Sara D
Fukumoto Takeshi
Fuller John E
Fux Blima
Gaal Peter Andras
Gadanya Muktar A
Gaidhane Abhay Motiramji
Gaihre Santosh
Gakidou Emmanuela
Galali Yaseen
Galles Natalie C
Gallus Silvano
Ganbat Mandukhai
Gandhi Aravind P
Ganesan Balasankar
Ganiyani Mohammad Arfat
Garcia-Gordillo MA
Gardner William M
Garg Jalaj
Garg Naval
Gautam Rupesh K
Gbadamosi Semiu Olatunde
Gebi Tilaye Gebru
Gebregergis Miglas W
Gebrehiwot Mesfin
Gebremeskel Teferi Gebru
Georgescu Simona Roxana
Getachew Tamirat
Gething Peter W
Getie Molla
Ghadiri Keyghobad
Ghahramani Sulmaz
Ghailan Khalid Yaser
Ghasemi Mohammad-Reza
Ghasempour Dabaghi Ghazal
Ghasemzadeh Afsaneh
Ghashghaee Ahmad
Ghassemi Fariba
Ghazy Ramy Mohamed
Ghimire Ajnish
Ghoba Sama
Gholamalizadeh Maryam
Gholamian Asadollah
Gholamrezanezhad Ali
Gholizadeh Nasim
Ghorbani Vajargah Pooyan
Ghorbani Mahsa
Ghoshal Aloke Gopal
Gill Paramjit Singh
Gill Tiffany K
Gillum Richard F
Ginindza Themba G
Girmay Alem
Glasbey James C
Gnedovskaya Elena V
Godinho Myron Anthony
Goel Amit
Golchin Ali
Goldust Mohamad
Golechha Mahaveer
Goleij Pouya
Gomes Nelson G M
Gona Philimon N
Gopalani Sameer Vali
Gorini Giuseppe
Goudarzi Houman
Goulart Alessandra C
Goulart Bárbara Niegia Garcia
Goyal Anmol
Grada Ayman
Graham Simon Matthew
Grivna Michal
Grosso Giuseppe
Guan Shi-Yang
Guarducci Giovanni
Gubari Mohammed Ibrahim Mohialdeen
Gudeta Mesay Dechasa
Guha Avirup
Guicciardi Stefano
Guimarães Rafael Alves
Gulati Snigdha
Gunawardane Damitha Asanga
Gunturu Sasidhar
Guo Cui
Gupta Anish Kumar
Gupta Bhawna
Gupta Manoj Kumar
Gupta Mohak
Gupta Rajat Das
Gupta Rajeev
Gupta Sapna
Gupta Veer Bala
Gupta Vijai Kumar
Gupta Vivek Kumar
Gurmessa Lami
Gutiérrez Reyna Alma
Göbölös Laszlo
Habibzadeh Farrokh
Habibzadeh Parham
Haddadi Rasool
Hadei Mostafa
Hadi Najah R
Haep Nils
Hafezi-Nejad Nima
Hailu Alemayehu
Haj-Mirzaian Arvin
Halboub Esam S
Hall Brian J
Haller Sebastian
Halwani Rabih
Hamadeh Randah R
Hameed Sajid
Hamidi Samer
Hamilton Erin B
Han Chieh
Han Qiuxia
Hanif Asif
Hanifi Nasrin
Hankey Graeme J
Hanna Fahad
Hannan Md Abdul
Haque Md Nuruzzaman
Harapan Harapan
Hargono Arief
Haro Josep Maria
Hasaballah Ahmed I
Hasan Ikramul
Hasan M Tasdik
Hasani Hamidreza
Hasanian Mohammad
Hashi Abdiwahab
Hasnain Md Saquib
Hassan Ikrama
Hassanipour Soheil
Hassankhani Hadi
Haubold Johannes
Havmoeller Rasmus J
Hay Simon I
He Jiawei
Hebert Jeffrey J
Hegazi Omar E
Heidari Golnaz
Heidari Mohammad
Heidari-Foroozan Mahsa
Helfer Bartosz
Hendrie Delia
Herrera-Serna Brenda Yuliana
Herteliu Claudiu
Hesami Hamed
Hezam Kamal
Hill Catherine L
Hiraike Yuta
Holla Ramesh
Horita Nobuyuki
Hossain Md Mahbub
Hossain Sahadat
Hosseini Mohammad-Salar
Hosseinzadeh Adli Ahmad
Hosseinzadeh Hassan
Hosseinzadeh Mehdi
Hostiuc Mihaela
Hostiuc Sorin
Hsairi Mohamed
Hsieh Vivian Chia-rong
Hsu Rebecca L
Hu Chengxi
Huang Junjie
Hultström Michael
Humayun Ayesha
Hundie Tsegaye Gebreyes
Hussain Javid
Hussain M Azhar
Hussein Nawfal R
Hussien Foziya Mohammed
Huynh Hong-Han
Hwang Bing-Fang
Ibitoye Segun Emmanuel
Ibrahim Khalid S
Iftikhar Pulwasha Maria
Ijo Desta
Ikiroma Adalia I
Ikuta Kevin S
Ikwegbue Paul Chukwudi
Ilesanmi Olayinka Stephen
Ilic Irena M
Ilic Milena D
Imam Mohammad Tarique
Immurana Mustapha
Inamdar Sumant
Indriasih Endang
Iqhrammullah Muhammad
Iradukunda Arnaud
Iregbu Kenneth Chukwuemeka
Islam Md Rabiul
Islam Sheikh Mohammed Shariful
Islami Farhad
Ismail Faisal
Ismail Nahlah Elkudssiah
Iso Hiroyasu
Isola Gaetano
Iwagami Masao
Iwu Chidozie C D
Iyamu Ihoghosa Osamuyi
Iyer Mahalaxmi
J Linda Merin
Jaafari Jalil
Jacob Louis
Jacobsen Kathryn H
Jadidi-Niaragh Farhad
Jafarinia Morteza
Jafarzadeh Abdollah
Jaggi Khushleen
Jahankhani Kasra
Jahanmehr Nader
Jahrami Haitham
Jain Nityanand
Jairoun Ammar Abdulrahman
Jaiswal Abhishek
Jamshidi Elham
Janko Mark M
Jatau Abubakar Ibrahim
Javadov Sabzali
Javaheri Tahereh
Jayapal Sathish Kumar
Jayaram Shubha
Jebai Rime
Jee Sun Ha
Jeganathan Jayakumar
Jha Anil K
Jha Ravi Prakash
Jiang Heng
Jin Yingzhao
Johnson Olatunji
Jokar Mohammad
Jonas Jost B
Joo Tamas
Joseph Abel
Joseph Nitin
Joshua Charity Ehimwenma
Joshy Grace
Jozwiak Jacek Jerzy
Jürisson Mikk
K Vaishali
Kaambwa Billingsley
Kabir Ali
Kabir Zubair
Kadashetti Vidya
Kadir Dler Hussein
Kalani Rizwan
Kalankesh Laleh R
Kalankesh Leila R
Kaliyadan Feroze
Kalra Sanjay
Kamal Vineet Kumar
Kamarajah Sivesh Kathir
Kamath Rajesh
Kamiab Zahra
Kamyari Naser
Kanagasabai Thanigaivelan
Kanchan Tanuj
Kandel Himal
Kanmanthareddy Arun R
Kanmiki Edmund Wedam
Kanmodi Kehinde Kazeem
Kannan S Suthanthira
Kansal Sushil Kumar
Kantar Rami S
Kapoor Neeti
Karajizadeh Mehrdad
Karanth Shama D
Karasneh Reema A
Karaye Ibraheem M
Karch André
Karim Asima
Karimi Behnagh Arman
Karimi Salah Eddin
Kashoo Faizan Zaffar
Kasnazani Qalandar Hussein Abdulkarim
Kasraei Hengameh
Kassebaum Nicholas J
Kassel Molly B
Kauppila Joonas H
Kaur Navjot
Kawakami Norito
Kayode Gbenga A
Kazemi Foad
Kazemian Sina
Kazmi Tahseen Haider
Kebebew Getu Mosisa
Kebede Adera Debella
Kebede Fassikaw
Keflie Tibebeselassie S
Keiyoro Peter Njenga
Keller Cathleen
Kelly Jaimon Terence
Kempen John H
Kerr Jessica A
Kesse-Guyot Emmanuelle
Khajuria Himanshu
Khalaji Amirmohammad
Khalid Nauman
Khalil Anees Ahmed
Khalilian Alireza
Khamesipour Faham
Khan suheb Mahammed Ziauddin
Khan Ajmal
Khan Asaduzzaman
Khan Gulfaraz
Khan Ikramullah
Khan Imteyaz A
Khan M Nuruzzaman
Khan Maseer
Khan Mohammad Jobair
Khan Moien AB
Khan Zeeshan Ali
Khanmohammadi Shaghayegh
Khatab Khaled
Khatami Fatemeh
Khatatbeh Haitham
Khatatbeh Moawiah Mohammad
Khavandegar Armin
Khayat Kashani Hamid Reza
Khidri Feriha Fatima
Khodadoust Elaheh
Khorgamphar Mohammad
Khormali Moein
Khorrami Zahra
Khosravi Ahmad
Khosravi Mohammad Ali
Kifle Zemene Demelash
Kim Grace
Kim Jihee
Kim Kwanghyun
Kim Min Seo
Kim Yun Jin
Kimokoti Ruth W
Kinzel Kasey E
Kisa Adnan
Kisa Sezer
Klu Desmond
Knudsen Ann Kristin Skrindo
Kocarnik Jonathan M
Kochhar Sonali
Kocsis Timea
Koh David S Q
Kolahi Ali-Asghar
Kolves Kairi
Kompani Farzad
Koren Gerbrand
Kosen Soewarta
Kostev Karel
Koul Parvaiz A
Koulmane Laxminarayana Sindhura Lakshmi
Krishan Kewal
Krishna Hare
Krishna Varun
Krishnamoorthy Vijay
Krishnamoorthy Yuvaraj
Krohn Kris J
Kuate Defo Barthelemy
Kucuk Bicer Burcu
Kuddus Md Abdul
Kuddus Mohammed
Kuitunen Ilari
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Kulkarni Vishnutheertha
Kumar Akshay
Kumar Ashish
Kumar Harish
Kumar Manasi
Kumar Rakesh
Kumari Madhulata
Kumie Fantahun Tarekegn
Kundu Satyajit
Kurmi Om P
Kusnali Asep
Kusuma Dian
Kwarteng Alexander
Kyriopoulos Ilias
Kyu Hmwe Hmwe
La Vecchia Carlo
Lacey Ben
Ladan Muhammad Awwal
Laflamme Lucie
Lagat Abraham K
Lager Anton C J
Lahmar Abdelilah
Lai Daphne Teck Ching
Lal Dharmesh Kumar
Lalloo Ratilal
Lallukka Tea
Lam Hilton
Landrum Kelsey R
Lanfranchi Francesco
Lang Justin J
Langguth Berthold
Lansingh Van Charles
Laplante-Lévesque Ariane
Larijani Bagher
Larsson Anders O
Lasrado Savita
Lassi Zohra S
Latief Kamaluddin
Latifinaibin Kaveh
Lauriola Paolo
Le Nhi Huu Hanh
Le Thao Thi Thu
Le Trang Diep Thanh
Ledda Caterina
Ledesma Jorge R
Lee Munjae
Lee Paul H
Lee Seung Won
Lee Shaun Wen Huey
Lee Wei-Chen
Lee Yo Han
LeGrand Kate E
Leigh James
Leong Elvynna
Lerango Temesgen L
Li Ming-Chieh
Li Wei
Li Xiaopan
Li Yichong
Li Zhihui
Ligade Virendra S
Likaka Andrew Tiyamike Makhiringa
Lim Lee-Ling
Lim Stephen S
Lindstrom Megan
Linehan Christine
Liu Chaojie
Liu Gang
Liu Jue
Liu Runben
Liu Shiwei
Liu Xiaofeng
Liu Xuefeng
Llanaj Erand
Loftus Michael J
Lopukhov Platon D
Loreche Arianna Maever
Lorkowski Stefan
Lotufo Paulo A
Lozano Rafael
Lubinda Jailos
Lucchetti Giancarlo
Lugo Alessandra
Lunevicius Raimundas
Lám Judit
López-Bueno Rubén
Ma Zheng Feei
Maass Kelsey Lynn
Machairas Nikolaos
Machoy Monika
Madadizadeh Farzan
Madsen Christian
Madureira-Carvalho Áurea M
Maghazachi Azzam A
Maharaj Sandeep B
Mahjoub Soleiman
Mahmoud Mansour Adam
Mahmoudi Alireza
Mahmoudi Elham
Mahmoudi Razzagh
Majeed Azeem
Makhdoom Irsa Fatima
Malakan Rad Elaheh
Maled Venkatesh
Malekzadeh Reza
Malhotra Armaan K
Malhotra Kashish
Malik Ahmad Azam
Malik Iram
Malta Deborah Carvalho
Mamun Abdullah A
Mansouri Pejman
Mansournia Mohammad Ali
Mantovani Lorenzo Giovanni
Maqsood Sajid
Marasini Bishnu P
Marateb Hamid Reza
Maravilla Joemer C
Marconi Agustina M
Mardi Parham
Marino Mirko
Marjani Abdoljalal
Martinez Gabriel
Martinez-Guerra Bernardo Alfonso
Martinez-Piedra Ramon
Martini Daniela
Martini Santi
Martins-Melo Francisco Rogerlândio
Martorell Miquel
Marx Wolfgang
Maryam Sharmeen
Marzo Roy Rillera
Masaka Anthony
Masrie Awoke
Mathieson Stephanie
Mathioudakis Alexander G
Mathur Manu Raj
Mattumpuram Jishanth
Matzopoulos Richard
Maude Richard James
Maugeri Andrea
Maulik Pallab K
Mayeli Mahsa
Mazaheri Maryam
Mazidi Mohsen
McGrath John J
McKee Martin
McKowen Anna Laura W
McLaughlin Susan A
McPhail Steven M
Mechili Enkeleint A
Medina John Robert Carabeo
Mediratta Rishi P
Meena Jitendra Kumar
Mehra Rahul
Mehrabani-Zeinabad Kamran
Mehrabi Nasab Entezar
Mekene Meto Tesfahun
Meles Gebrekiros Gebremichael
Mendez-Lopez Max Alberto Mendez
Mendoza Walter
Menezes Ritesh G
Mengist Belayneh
Mentis Alexios-Fotios A
Meo Sultan Ayoub
Meresa Haftu Asmerom
Meretoja Atte
Meretoja Tuomo J
Mersha Abera M
Mesfin Bezawit Afework
Mestrovic Tomislav
Mettananda Kukulege Chamila Dinushi
Mettananda Sachith
Meylakhs Peter
Mhlanga Adquate
Mhlanga Laurette
Mi Tianyue
Miazgowski Tomasz
Micha Georgia
Michalek Irmina Maria
Miller Ted R
Mills Edward J
Minh Le Huu Nhat
Mini GK
Mir Mohammad Sadeghi Pouya
Mirica Andreea
Mirijello Antonio
Mirrakhimov Erkin M
Mirutse Mizan Kiros
Mirzaei Maryam
Misganaw Awoke
Mishra Ashim
Misra Sanjeev
Mitchell Philip B
Mithra Prasanna
Mittal Chaitanya
Mobayen Mohammadreza
Moberg Madeline E
Mohamadkhani Ashraf
Mohamed Jama
Mohamed Mouhand F H
Mohamed Nouh Saad
Mohammad-Alizadeh-Charandabi Sakineh
Mohammadi Soheil
Mohammadian-Hafshejani Abdollah
Mohammadifard Noushin
Mohammed Hassen
Mohammed Hussen
Mohammed Mustapha
Mohammed Salahuddin
Mohammed Shafiu
Mohan Viswanathan
Mojiri-Forushani Hoda
Mokari Amin
Mokdad Ali H
Molinaro Sabrina
Molokhia Mariam
Momtazmanesh Sara
Monasta Lorenzo
Mondello Stefania
Moni Mohammad Ali
Moodi Ghalibaf AmirAli
Moradi Maryam
Moradi Yousef
Moradi-Lakeh Maziar
Moradzadeh Maliheh
Moraga Paula
Morawska Lidia
Moreira Rafael Silveira
Morovatdar Negar
Morrison Shane Douglas
Morze Jakub
Mosser Jonathan F
Motappa Rohith
Mougin Vincent
Mouodi Simin
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Mousavi Parsa
Mousavi Seyed Ehsan
Mpolya Emmanuel A
Mrejen Matías
Mubarik Sumaira
Muccioli Lorenzo
Mueller Ulrich Otto
Mughal Faraz
Mukherjee Sumoni
Mulita Francesk
Munjal Kavita
Murillo-Zamora Efrén
Murray Christopher J L
Musaigwa Fungai
Musallam Khaled M
Mustafa Ahmad
Mustafa Ghulam
Muthupandian Saravanan
Muthusamy Raman
Muzaffar Muhammad
Myung Woojae
Nagarajan Ahamarshan Jayaraman
Nagel Gabriele
Naghavi Mohsen
Naghavi Pirouz
Naheed Aliya
Naik Ganesh R
Naik Gurudatta
Nainu Firzan
Nair Sanjeev
Najmuldeen Hastyar Hama Rashid
Nakhostin Ansari Noureddin
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Naqvi Atta Abbas
Narasimha Swamy Sreenivas
Narayana Aparna Ichalangod
Nargus Shumaila
Nascimento Bruno Ramos
Nascimento Gustavo G
Nasehi Samar
Nashwan Abdulqadir J
Natto Zuhair S
Nauman Javaid
Naveed Muhammad
Nayak Biswa Prakash
Nayak Vinod C
Nazri-Panjaki Athare
Ndejjo Rawlance
Nduaguba Sabina Onyinye
Negash Hadush
Negoi Ionut
Negoi Ruxandra Irina
Negru Serban Mircea
Nejadghaderi Seyed Aria
Nejjari Chakib
Nena Evangelia
Nepal Samata
Ng Marie
Nggada Haruna Asura
Nguefack-Tsague Georges
Ngunjiri Josephine W
Nguyen Anh Hoang
Nguyen Dang H
Nguyen Hau Thi Hien
Nguyen Phat Tuan
Nguyen Van Thanh
Niazi Robina Khan
Nielsen Katie R
Nigatu Yeshambel T
Nikolouzakis Taxiarchis Konstantinos
Nikoobar Ali
Nikoomanesh Fatemeh
Nikpoor Amin Reza
Ningrum Dina Nur Anggraini
Nnaji Chukwudi A
Nnyanzi Lawrence Achilles
Noman Efaq Ali
Nomura Shuhei
Noreen Mamoona
Noroozi Nafise
Norrving Bo
Noubiap Jean Jacques
Novotney Amanda
Nri-Ezedi Chisom Adaobi
Ntaios George
Ntsekhe Mpiko
Nurrika Dieta
Nutor Jerry John
Nuñez-Samudio Virginia
O'Donnell Martin James
Oancea Bogdan
Obamiro Kehinde O
Oboh Mary Aigbiremo
Odetokun Ismail A
Odogwu Nkechi Martina
Oduro Michael Safo
Ofakunrin Akinyemi O D
Ogunkoya Abiola
Oguntade Ayodipupo Sikiru
Oh In-Hwan
Okati-Aliabad Hassan
Okeke Sylvester Reuben
Okekunle Akinkunmi Paul
Okonji Osaretin Christabel
Olagunju Andrew T
Olaiya Muideen Tunbosun
Olatubi Matthew Idowu
Oliveira Gláucia Maria Moraes
Olufadewa Isaac Iyinoluwa
Olusanya Bolajoko Olubukunola
Olusanya Jacob Olusegun
Oluwafemi Yinka Doris
Omar Bali Ahmed
Omar Hany A
Omer Goran Latif
Ondayo Maureene Auma
Ong Kanyin Liane
Ong Sokking
Onwujekwe Obinna E
Onyedibe Kenneth Ikenna
Ordak Michal
Orisakwe Orish Ebere
Orish Verner N
Ortega-Altamirano Doris V
Ortiz Alberto
Osman Wael M S
Ostroff Samuel M
Osuagwu Uchechukwu Levi
Otoiu Adrian
Otstavnov Nikita
Otstavnov Stanislav S
Ouyahia Amel
Ouyang Guoqing
Owolabi Mayowa O
Ozten Yaz
P A Mahesh Padukudru
Padron-Monedero Alicia
Padubidri Jagadish Rao
Pal Pramod Kumar
Palicz Tamás
Palladino Claudia
Palladino Raffaele
Palma-Alvarez Raul Felipe
Pan Feng
Pan Hai-Feng
Pana Adrian
Panda Paramjot
Panda-Jonas Songhomitra
Pandi-Perumal Seithikurippu R
Pangaribuan Helena Ullyartha
Panos Georgios D
Panos Leonidas D
Pantazopoulos Ioannis
Pantea Stoian Anca Mihaela
Papadopoulou Paraskevi
Parikh Romil R
Park Seoyeon
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Pashaei Ava
Pasovic Maja
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Pasupula Deepak Kumar
Patel Hemal M
Patel Jay
Patel Sangram Kishor
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Patoulias Dimitrios
Patthipati Venkata Suresh
Paudel Uttam
Pazoki Toroudi Hamidreza
Pease Spencer A
Peden Amy E
Pedersini Paolo
Pensato Umberto
Pepito Veincent Christian Filipino
Peprah Emmanuel K
Peprah Prince
Perdigão João
Pereira Marcos
Peres Mario F P
Perianayagam Arokiasamy
Perico Norberto
Pestell Richard G
Pesudovs Konrad
Petermann-Rocha Fanny Emily
Petri William A
Pham Hoang Tran
Philip Anil K
Phillips Michael R
Pierannunzio Daniela
Pigeolet Manon
Pigott David M
Pilgrim Thomas
Piracha Zahra Zahid
Piradov Michael A
Pirouzpanah Saeed
Plakkal Nishad
Plotnikov Evgenii
Podder Vivek
Poddighe Dimitri
Polinder Suzanne
Polkinghorne Kevan R
Poluru Ramesh
Ponkilainen Ville T
Porru Fabio
Postma Maarten J
Poudel Govinda Raj
Pourshams Akram
Pourtaheri Naeimeh
Prada Sergio I
Pradhan Pranil Man Singh
Prakasham Thejeswar N
Prasad Manya
Prashant Akila
Prates Elton Junio Sady
Prieto Alhambra Daniel
PRISCILLA TINA
Pritchett Natalie
Purohit Bharathi M
Puvvula Jagadeesh
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Qian Gangzhen
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Rafferty Quinn
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Raheem Nasiru
Rahim Fakher
Rahim Md Jillur
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Rahman Mohammad Hifz Ur
Rahman Mosiur
Rahman Muhammad Aziz
Rahmani Amir Masoud
Rahmani Shayan
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Rakovac Ivo
Ramasamy Shakthi Kumaran
Ramazanu Sheena
Rana Kritika
Ranabhat Chhabi Lal
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Rane Amey
Rao Chythra R
Rao Indu Ramachandra
Rao Mithun
Rao Sowmya J
Rasali Drona Prakash
Rasella Davide
Rashedi Sina
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Rashidi Mohammad-Mahdi
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Rasul Azad
Rathnaiah Babu Giridhara
Rauniyar Santosh Kumar
Ravangard Ramin
Ravikumar Nakul
Rawaf David Laith
Rawaf Salman
Rawal Lal
Rawassizadeh Reza
Rawlley Bharat
Raza Rabail Zehra
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Redwan Elrashdy Moustafa Mohamed
Rehman Faizan Ur
Reifels Lennart
Reiner Jr Robert C
Remuzzi Giuseppe
Reyes Luis Felipe
Rezaei Maryam
Rezaei Nazila
Rezaei Negar
Rezaeian Mohsen
Rhee Taeho Gregory
Riaz Mavra A
Ribeiro Antonio Luiz P
Rickard Jennifer
Riva Hannah R
Robinson-Oden Hannah Elizabeth
Rodrigues Célia Fortuna
Rodrigues Mónica
Roever Leonardo
Rogowski Emma Lynn Best
Rohloff Peter
Romadlon Debby Syahru
Romero-Rodríguez Esperanza
Romoli Michele
Ronfani Luca
Roshandel Gholamreza
Roth Gregory A
Rout Himanshu Sekhar
Roy Nitai
Roy Priyanka
Rubagotti Enrico
Ruela Guilherme de Andrade
Rumisha Susan Fred
Runghien Tilleye
Rwegerera Godfrey M
Rynkiewicz Andrzej
S N Chandan
Saad Aly M A
Saadatian Zahra
Saber Korosh
Saber-Ayad Maha Mohamed
SaberiKamarposhti Morteza
Sabour Siamak
Sacco Simona
Sachdev Perminder S
Sachdeva Rajesh
Saddik Basema
Saddler Adam
Sadee Bashdar Abuzed
Sadeghi Ehsan
Sadeghi Erfan
Sadeghian Farideh
Saeb Mohammad Reza
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Safaeinejad Fahimeh
Safi Sher Zaman
Sagar Rajesh
Saghazadeh Amene
Sagoe Dominic
Saheb Sharif-Askari Fatemeh
Saheb Sharif-Askari Narjes
Sahebkar Amirhossein
Sahoo Soumya Swaroop
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Sahu Monalisha
Saif Zahra
Sajid Mirza Rizwan
Sakshaug Joseph W
Salam Nasir
Salamati Payman
Salami Afeez Abolarinwa
Salaroli Luciane B
Saleh Mohamed A
Salehi Sana
Salem Marwa Rashad
Salem Mohammed Z Y
Salimi Sohrab
Samadi Kafil Hossein
Samadzadeh Sara
Samargandy Saad
Samodra Yoseph Leonardo
Samy Abdallah M
Sanabria Juan
Sanna Francesca
Santomauro Damian Francesco
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Singal Anjali
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Wondimagegene Yohannes Addisu
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Xu Xiaoyue
Xu Yvonne Yiru
Yadollahpour Ali
Yamagishi Kazumasa
Yang Danting
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Yano Yuichiro
Yao Yao
Yaribeygi Habib
Ye Pengpeng
Yehualashet Sisay Shewasinad
Yesiltepe Metin
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Yezli Saber
Yi Siyan
Yigezu Amanuel
Yip Paul
Yismaw Malede Berihun
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Yiğit Arzu
Yiğit Vahit
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Zadey Siddhesh
Zadnik Vesna
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Zarrintan Armin
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Zeinali Zahra
Zhang Haijun
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Zhang Jingya
Zhang Liqun
Zhang Yunquan
Zhang Zhi-Jiang
Zhao Hanqing
Zhong Chenwen
Zhou Juexiao
Zhu Bin
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Zielińska Magdalena
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Zou Zhiyong
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Zumla Alimuddin
Zweck Elric
Zyoud Samer H
Ärnlöv Johan
Šekerija Mario
Publication venue: Elsevier
Publication date: 03/04/2024
Field of study

BACKGROUND Regular, detailed reporting on population health by underlying cause of death is fundamental for public health decision making. Cause-specific estimates of mortality and the subsequent effects on life expectancy worldwide are valuable metrics to gauge progress in reducing mortality rates. These estimates are particularly important following large-scale mortality spikes, such as the COVID-19 pandemic. When systematically analysed, mortality rates and life expectancy allow comparisons of the consequences of causes of death globally and over time, providing a nuanced understanding of the effect of these causes on global populations. METHODS The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 cause-of-death analysis estimated mortality and years of life lost (YLLs) from 288 causes of death by age-sex-location-year in 204 countries and territories and 811 subnational locations for each year from 1990 until 2021. The analysis used 56 604 data sources, including data from vital registration and verbal autopsy as well as surveys, censuses, surveillance systems, and cancer registries, among others. As with previous GBD rounds, cause-specific death rates for most causes were estimated using the Cause of Death Ensemble model-a modelling tool developed for GBD to assess the out-of-sample predictive validity of different statistical models and covariate permutations and combine those results to produce cause-specific mortality estimates-with alternative strategies adapted to model causes with insufficient data, substantial changes in reporting over the study period, or unusual epidemiology. YLLs were computed as the product of the number of deaths for each cause-age-sex-location-year and the standard life expectancy at each age. As part of the modelling process, uncertainty intervals (UIs) were generated using the 2·5th and 97·5th percentiles from a 1000-draw distribution for each metric. We decomposed life expectancy by cause of death, location, and year to show cause-specific effects on life expectancy from 1990 to 2021. We also used the coefficient of variation and the fraction of population affected by 90% of deaths to highlight concentrations of mortality. Findings are reported in counts and age-standardised rates. Methodological improvements for cause-of-death estimates in GBD 2021 include the expansion of under-5-years age group to include four new age groups, enhanced methods to account for stochastic variation of sparse data, and the inclusion of COVID-19 and other pandemic-related mortality-which includes excess mortality associated with the pandemic, excluding COVID-19, lower respiratory infections, measles, malaria, and pertussis. For this analysis, 199 new country-years of vital registration cause-of-death data, 5 country-years of surveillance data, 21 country-years of verbal autopsy data, and 94 country-years of other data types were added to those used in previous GBD rounds. FINDINGS The leading causes of age-standardised deaths globally were the same in 2019 as they were in 1990; in descending order, these were, ischaemic heart disease, stroke, chronic obstructive pulmonary disease, and lower respiratory infections. In 2021, however, COVID-19 replaced stroke as the second-leading age-standardised cause of death, with 94·0 deaths (95% UI 89·2-100·0) per 100 000 population. The COVID-19 pandemic shifted the rankings of the leading five causes, lowering stroke to the third-leading and chronic obstructive pulmonary disease to the fourth-leading position. In 2021, the highest age-standardised death rates from COVID-19 occurred in sub-Saharan Africa (271·0 deaths [250·1-290·7] per 100 000 population) and Latin America and the Caribbean (195·4 deaths [182·1-211·4] per 100 000 population). The lowest age-standardised death rates from COVID-19 were in the high-income super-region (48·1 deaths [47·4-48·8] per 100 000 population) and southeast Asia, east Asia, and Oceania (23·2 deaths [16·3-37·2] per 100 000 population). Globally, life expectancy steadily improved between 1990 and 2019 for 18 of the 22 investigated causes. Decomposition of global and regional life expectancy showed the positive effect that reductions in deaths from enteric infections, lower respiratory infections, stroke, and neonatal deaths, among others have contributed to improved survival over the study period. However, a net reduction of 1·6 years occurred in global life expectancy between 2019 and 2021, primarily due to increased death rates from COVID-19 and other pandemic-related mortality. Life expectancy was highly variable between super-regions over the study period, with southeast Asia, east Asia, and Oceania gaining 8·3 years (6·7-9·9) overall, while having the smallest reduction in life expectancy due to COVID-19 (0·4 years). The largest reduction in life expectancy due to COVID-19 occurred in Latin America and the Caribbean (3·6 years). Additionally, 53 of the 288 causes of death were highly concentrated in locations with less than 50% of the global population as of 2021, and these causes of death became progressively more concentrated since 1990, when only 44 causes showed this pattern. The concentration phenomenon is discussed heuristically with respect to enteric and lower respiratory infections, malaria, HIV/AIDS, neonatal disorders, tuberculosis, and measles. INTERPRETATION Long-standing gains in life expectancy and reductions in many of the leading causes of death have been disrupted by the COVID-19 pandemic, the adverse effects of which were spread unevenly among populations. Despite the pandemic, there has been continued progress in combatting several notable causes of death, leading to improved global life expectancy over the study period. Each of the seven GBD super-regions showed an overall improvement from 1990 and 2021, obscuring the negative effect in the years of the pandemic. Additionally, our findings regarding regional variation in causes of death driving increases in life expectancy hold clear policy utility. Analyses of shifting mortality trends reveal that several causes, once widespread globally, are now increasingly concentrated geographically. These changes in mortality concentration, alongside further investigation of changing risks, interventions, and relevant policy, present an important opportunity to deepen our understanding of mortality-reduction strategies. Examining patterns in mortality concentration might reveal areas where successful public health interventions have been implemented. Translating these successes to locations where certain causes of death remain entrenched can inform policies that work to improve life expectancy for people everywhere. FUNDING Bill & Melinda Gates Foundation

Central Archive at the University of Reading