Gamma-Ray Constraints on Maximum Cosmogenic Neutrino Fluxes and UHECR Source Evolution Models

The dip model assumes that the ultra-high energy cosmic rays (UHECRs) above 10$^{18}$ eV consist exclusively of protons and is consistent with the spectrum and composition measure by HiRes. Here we present the range of cosmogenic neutrino fluxes in the dip-model which are compatible with a recent determination of the extragalactic very high energy (VHE) gamma-ray diffuse background derived from 2.5 years of Fermi/LAT data. We show that the largest fluxes predicted in the dip model would be detectable by IceCube in about 10 years of observation and are within the reach of a few years of observation with the ARA project. In the incomplete UHECR model in which protons are assumed to dominate only above 10$^{19}$ eV, the cosmogenic neutrino fluxes could be a factor of 2 or 3 larger. Any fraction of heavier nuclei in the UHECR at these energies would reduce the maximum cosmogenic neutrino fluxes. We also consider here special evolution models in which the UHECR sources are assumed to have the same evolution of either the star formation rate (SFR), or the gamma-ray burst (GRB) rate, or the active galactic nuclei (AGN) rate in the Universe and found that the last two are disfavored (and in the dip model rejected) by the new VHE gamma-ray background.Comment: 19 pages, 16 figures, JHEP3.cls needed to typese

An Anglo-Saxon execution cemetery at Walkington Wold, Yorkshire

This paper presents a re-evaluation of a cemetery excavated over 30 years ago at Walkington Wold in east Yorkshire. The cemetery is characterized by careless burial on diverse alignments, and by the fact that most of the skeletons did not have associated crania. The cemetery has been variously described as being the result of an early post-Roman massacre, as providing evidence for a ‘Celtic’ head cult or as an Anglo-Saxon execution cemetery. In order to resolve the matter, radiocarbon dates were acquired and a re-examination of the skeletal remains was undertaken. It was confirmed that the cemetery was an Anglo-Saxon execution cemetery, the only known example from northern England, and the site is set into its wider context in the paper

Measurement of the Atmospheric Muon Spectrum from 20 to 3000 GeV

The absolute muon flux between 20 GeV and 3000 GeV is measured with the L3 magnetic muon spectrometer for zenith angles ranging from 0 degree to 58 degree. Due to the large exposure of about 150 m2 sr d, and the excellent momentum resolution of the L3 muon chambers, a precision of 2.3 % at 150 GeV in the vertical direction is achieved. The ratio of positive to negative muons is studied between 20 GeV and 500 GeV, and the average vertical muon charge ratio is found to be 1.285 +- 0.003 (stat.) +- 0.019 (syst.).Comment: Total 32 pages, 9Figure

Olber's Paradox for Superluminal Neutrinos: Constraining Extreme Neutrino Speeds at TeV-ZeV Energies with the Diffuse Neutrino Background

The only invariant speed in special relativity is c; therefore, if some neutrinos travel at even tiny speeds above c, normal special relativity is incomplete and any superluminal speed may be possible. I derive a limit on superluminal neutrino speeds v >> c at high energies by noting that such speeds would increase the size of the neutrino horizon. The increased volume of the Universe visible leads to a brighter astrophysical neutrino background. The nondetection of "guaranteed" neutrino backgrounds from star-forming galaxies and ultrahigh energy cosmic rays (UHECRs) constrains v/c at TeV--ZeV energies. I find that v/c <= 820 at 60 TeV from the nondetection of neutrinos from star-forming galaxies. The nondetection of neutrinos from UHECRs constrains v/c to be less than 2500 at 0.1 EeV in a pessimistic model and less than 4.6 at 4 EeV in an optimistic model. The UHECR neutrino background nondetection is strongly inconsistent with a naive quadratic extrapolation of the OPERA results to EeV energies. The limits apply subject to some caveats, particularly that the expected pionic neutrino backgrounds exist and that neutrinos travel faster than c when they pass the detector. They could be improved substantially as the expected neutrino backgrounds are better understood and with new experimental neutrino background limits. I also point out that extremely subluminal speeds would result in a much smaller neutrino background intensity than expected.Comment: 13 pages, 2 figures, fixed titl

The age and hydrological history of Blue Lake, South Australia

Three sediment cores from the Blue Lake, a groundwater fed lake of volcanic origin in South Australia, have been investigated using a range of chemical and isotopic parameters. The C-14 activity of both the inorganic and organic carbon fractions of the sediment decreases monotonically with depth. The rate of change with depth is greater for near-surface samples with an apparent hiatus in sedimentation rate at about 7000 yr B.P. Estimates of age for the precipitated authigenic carbonate, after correction for dilution with dead carbon from the groundwater, agree well with calculated ages from the organic carbon fraction of the sediment. We suggest the lake is much older than previously proposed using other dating techniques. Variations in the delta(13)C and delta(18)O composition of the authigenic carbonate reflect different residence times of dissolved inorganic carbon and water in the lake caused by changes in the lake level. During periods of hydrologic steady-state, it is suggested that relative changes in the temperature of the lake can be seen in delta(18)O changes in authigenic carbonate. Blue Lake has been undergoing sedimentation for at least 28,000 years, including two lengthy periods of hydrologic steady state. The lake, for a large proportion of its existence, was much shallower while for the last 7000 years has maintained a level close to the present one. The influence of pumping from the lake for urban water supply during this century is reflected in the isotopic composition of carbonate in the sediment

Genotoxic effect induced by hydrogen peroxide in human hepatoma cells using comet assay

Background: Hydrogen peroxide is a common reactive oxygen intermediate generated by variousforms of oxidative stress. Aims: The aim of this study was to investigate the DNA damage capacity ofH2O2 in HepG2 cells. Methods: Cells were treated with H2O2 at concentrations of 25 μM or 50 μM for5 min, 30 min, 40 min, 1 h or 24 h in parallel. The extent of DNA damage was assessed by the cometassay. Results: Compared to the control, DNA damage by 25 μM and 50 μM H2O2 increasedsignificantly with increasing incubation time up to 1 h, but it was not increased at 24 h. Conclusions:Our Findings confirm that H2O2 is a typical DNA damage inducing agent and thus is a good modelsystem to study the effects of oxidative stress. DNA damage in HepG2 cells increased significantlywith H2O2 concentration and time of incubation but later decreased likely due to DNA repairmechanisms and antioxidant enzyme

The Physics of Star Cluster Formation and Evolution

© 2020 Springer-Verlag. The final publication is available at Springer via https://doi.org/10.1007/s11214-020-00689-4.Star clusters form in dense, hierarchically collapsing gas clouds. Bulk kinetic energy is transformed to turbulence with stars forming from cores fed by filaments. In the most compact regions, stellar feedback is least effective in removing the gas and stars may form very efficiently. These are also the regions where, in high-mass clusters, ejecta from some kind of high-mass stars are effectively captured during the formation phase of some of the low mass stars and effectively channeled into the latter to form multiple populations. Star formation epochs in star clusters are generally set by gas flows that determine the abundance of gas in the cluster. We argue that there is likely only one star formation epoch after which clusters remain essentially clear of gas by cluster winds. Collisional dynamics is important in this phase leading to core collapse, expansion and eventual dispersion of every cluster. We review recent developments in the field with a focus on theoretical work.Peer reviewe

Novel genetic loci associated with hippocampal volume

The hippocampal formation is a brain structure integrally involved in episodic memory, spatial navigation, cognition and stress responsiveness. Structural abnormalities in hippocampal volume and shape are found in several common neuropsychiatric disorders. To identify the genetic underpinnings of hippocampal structure here we perform a genome-wide association study (GWAS) of 33,536 individuals and discover six independent loci significantly associated with hippocampal volume, four of them novel. Of the novel loci, three lie within genes (ASTN2, DPP4 and MAST4) and one is found 200 kb upstream of SHH. A hippocampal subfield analysis shows that a locus within the MSRB3 gene shows evidence of a localized effect along the dentate gyrus, subiculum, CA1 and fissure. Further, we show that genetic variants associated with decreased hippocampal volume are also associated with increased risk for Alzheimer's disease (rg =-0.155). Our findings suggest novel biological pathways through which human genetic variation influences hippocampal volume and risk for neuropsychiatric illness

Search for leptophobic Z ' bosons decaying into four-lepton final states in proton-proton collisions at root s=8 TeV

Peer reviewe