31 research outputs found

    Quantifying the interdisciplinarity of scientific journals and fields

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    There is an overall perception of increased interdisciplinarity in science, but this is difficult to confirm quantitatively owing to the lack of adequate methods to evaluate subjective phenomena. This is no different from the difficulties in establishing quantitative relationships in human and social sciences. In this paper we quantified the interdisciplinarity of scientific journals and science fields by using an entropy measurement based on the diversity of the subject categories of journals citing a specific journal. The methodology consisted in building citation networks using the Journal Citation Reports database, in which the nodes were journals and edges were established based on citations among journals. The overall network for the 11-year period (1999-2009) studied was small-world and scale free with regard to the in-strength. Upon visualizing the network topology an overall structure of the various science fields could be inferred, especially their interconnections. We confirmed quantitatively that science fields are becoming increasingly interdisciplinary, with the degree of interdisplinarity (i.e. entropy) correlating strongly with the in-strength of journals and with the impact factor.Comment: 23 pages, 6 figure

    Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2015: A systematic analysis for the Global Burden of Disease Study 2015

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    Background: The Global Burden of Diseases, Injuries, and Risk Factors Study 2015 provides an up-to-date synthesis of the evidence for risk factor exposure and the attributable burden of disease. By providing national and subnational assessments spanning the past 25 years, this study can inform debates on the importance of addressing risks in context. Methods: We used the comparative risk assessment framework developed for previous iterations of the Global Burden of Disease Study to estimate attributable deaths, disability-adjusted life-years (DALYs), and trends in exposure by age group, sex, year, and geography for 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks from 1990 to 2015. This study included 388 risk-outcome pairs that met World Cancer Research Fund-defined criteria for convincing or probable evidence. We extracted relative risk and exposure estimates from randomised controlled trials, cohorts, pooled cohorts, household surveys, census data, satellite data, and other sources. We used statistical models to pool data, adjust for bias, and incorporate covariates. We developed a metric that allows comparisons of exposure across risk factors—the summary exposure value. Using the counterfactual scenario of theoretical minimum risk level, we estimated the portion of deaths and DALYs that could be attributed to a given risk. We decomposed trends in attributable burden into contributions from population growth, population age structure, risk exposure, and risk-deleted cause-specific DALY rates. We characterised risk exposure in relation to a Socio-demographic Index (SDI). Findings: Between 1990 and 2015, global exposure to unsafe sanitation, household air pollution, childhood underweight, childhood stunting, and smoking each decreased by more than 25%. Global exposure for several occupational risks, high body-mass index (BMI), and drug use increased by more than 25% over the same period. All risks jointly evaluated in 2015 accounted for 57·8% (95% CI 56·6–58·8) of global deaths and 41·2% (39·8–42·8) of DALYs. In 2015, the ten largest contributors to global DALYs among Level 3 risks were high systolic blood pressure (211·8 million [192·7 million to 231·1 million] global DALYs), smoking (148·6 million [134·2 million to 163·1 million]), high fasting plasma glucose (143·1 million [125·1 million to 163·5 million]), high BMI (120·1 million [83·8 million to 158·4 million]), childhood undernutrition (113·3 million [103·9 million to 123·4 million]), ambient particulate matter (103·1 million [90·8 million to 115·1 million]), high total cholesterol (88·7 million [74·6 million to 105·7 million]), household air pollution (85·6 million [66·7 million to 106·1 million]), alcohol use (85·0 million [77·2 million to 93·0 million]), and diets high in sodium (83·0 million [49·3 million to 127·5 million]). From 1990 to 2015, attributable DALYs declined for micronutrient deficiencies, childhood undernutrition, unsafe sanitation and water, and household air pollution; reductions in risk-deleted DALY rates rather than reductions in exposure drove these declines. Rising exposure contributed to notable increases in attributable DALYs from high BMI, high fasting plasma glucose, occupational carcinogens, and drug use. Environmental risks and childhood undernutrition declined steadily with SDI; low physical activity, high BMI, and high fasting plasma glucose increased with SDI. In 119 countries, metabolic risks, such as high BMI and fasting plasma glucose, contributed the most attributable DALYs in 2015. Regionally, smoking still ranked among the leading five risk factors for attributable DALYs in 109 countries; childhood underweight and unsafe sex remained primary drivers of early death and disability in much of sub-Saharan Africa. Interpretation: Declines in some key environmental risks have contributed to declines in critical infectious diseases. Some risks appear to be invariant to SDI. Increasing risks, including high BMI, high fasting plasma glucose, drug use, and some occupational exposures, contribute to rising burden from some conditions, but also provide opportunities for intervention. Some highly preventable risks, such as smoking, remain major causes of attributable DALYs, even as exposure is declining. Public policy makers need to pay attention to the risks that are increasingly major contributors to global burden. Funding: Bill & Melinda Gates Foundation

    Measurements of ultrastrong magnetic fields during relativistic laser-plasma interactions

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    Measurements of magnetic fields generated during ultrahigh intensity (>10 19Wcm -2), short pulse (0.7-1 ps) laser-solid target interaction experiments are reported. An innovative method is used and the results are compared with particle-in-cell simulations. It is shown that polarization measurements of the self-generated harmonics of the laser can provide a convenient method for diagnosing the magnetic field - and that the experimental measurements indicate the existence of peak fields greater than 340 MG and below 460 MG at such high intensities. In particular, the observation of the X-wave cutoffs and the observed induced ellipticity of the harmonics can provide a reliable method for measuring these fields. These observations are important for evaluating the use of intense lasers in various potential applications and perhaps for understanding the complex physics of exotic astrophysical objects such as neutron stars. © 2002 American Institute of Physics

    Using self-generated harmonics as a diagnostic of high intensity laser-produced plasmas

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    The interaction of high intensity laser pulses (up to I ∼ 1020 W cm-2) with plasmas can generate very high order harmonics of the laser frequency (up to the 75th order have been observed). Measurements of the properties of these harmonics can provide important insights into the plasma conditions which exist during such interactions. For example, observations of the spectrum of the harmonic emission can provide information of the dynamics of the critical surface as well as information on relativistic non-linear optical effects in the plasma. However, most importantly, observations of the polarization properties of the harmonics can provide a method to measure the ultra-strong magnetic fields (greater than 350 MG) which can be generated during these interactions. It is likely that such techniques can be scaled to provide a significant amount of information from experiments at even higher intensities

    Observation of a highly directional gamma-ray beam from ultrashort, ultraintense laser pulse interactions with solids

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    Novel measurements of electromagnetic radiation above 10 MeV are presented for ultra intense laser pulse interactions with solids. A bright, highly directional source of y rays was observed directly behind the target. The y rays were produced by bremsstrahlung radiation from energetic electrons generated during the interaction. They were measured using the photoneutron reaction [63Cu(γ,n)62Cu] in copper. The resulting activity was measured by coincidence counting the positron annihilation γ rays which were produced from the decay of 62Cu. New measurements of the bremsstrahlung radiation at 1019 W cm-2 are also presented. © 1999 American Institute of Physics
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