10 research outputs found

    The HD 260655 system : two rocky worlds transiting a bright M dwarf at 10 pc

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    We report the discovery of a multiplanetary system transiting the M0 V dwarf HD 260655 (GJ 239, TOI-4599). The system consists of at least two transiting planets, namely HD 260655 b, with a period of 2.77 d, a radius of Rb = 1.240 ± 0.023 R⊕, a mass of Mb = 2.14 ± 0.34 M⊕, and a bulk density of ρb = 6.2 ± 1.0 g cm−3, and HD 260655 c, with a period of 5.71 d, a radius of , a mass of Mc = 3.09 ± 0.48 M⊕, and a bulk density of g cm−3. The planets have been detected in transit by the Transiting Exoplanet Survey Satellite (TESS) mission and confirmed independently with archival and new precise radial velocities obtained with the HIRES and CARMENES instruments since 1998 and 2016, respectively. At a distance of 10 pc, HD 260655 has become the fourth closest known multitransiting planet system after HD 219134, LTT 1445 A, and AU Mic. Due to the apparent brightness of the host star (J = 6.7 mag), both planets are among the most suitable rocky worlds known today for atmospheric studies with the James Webb Space Telescope, both in transmission and emission

    Enhanced leishmanicidal activity of cryptopeptide chimeras from the active N1 domain of bovine lactoferrin

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    wo antimicrobial cryptopeptides from the N1 domain of bovine lactoferrin, lactoferricin (LFcin17-30) and lactoferrampin (LFampin265-284), together with a hybrid version (LFchimera), were tested against the protozoan parasite Leishmania. All peptides were leishmanicidal against Leishmania donovani promastigotes, and LFchimera showed a significantly higher activity over its two composing moieties. Besides, it was the only peptide active on Leishmania pifanoi axenic amastigotes, already showing activity below 10 μM. To investigate their leishmanicidal mechanism, promastigote membrane permeabilization was assessed by decrease of free ATP levels in living parasites, entrance of the vital dye SYTOX Green (MW = 600 Da) and confocal and transmission electron microscopy. The peptides induced plasma membrane permeabilization and bioenergetic collapse of the parasites. To further clarify the structural traits underlying the increased leishmanicidal activity of LFchimera, the activity of several analogues was assessed. Results revealed that the high activity of these hybrid peptides seems to be related to the order and sequence orientation of the two cryptopeptide moieties, rather than to their particular linkage through an additional lysine, as in the initial LFchimera. The incorporation of both antimicrobial cryptopeptide motifs into a single linear sequence facilitates chemical synthesis and should help in the potential clinical application of these optimized analogues

    TOI-519 b: A short-period substellar object around an M dwarf validated using multicolour photometry and phase curve analysis

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    Context. We report the discovery of TOI-519 b (TIC 218795833), a transiting substellar object (R = 1.07 RJup) orbiting a faint M dwarf (V = 17.35) on a 1.26 d orbit. Brown dwarfs and massive planets orbiting M dwarfs on short-period orbits are rare, but more have already been discovered than expected from planet formation models. TOI-519 is a valuable addition to this group of unlikely systems, and it adds towards our understanding of the boundaries of planet formation. Aims: We set out to determine the nature of the Transiting Exoplanet Survey Satellite (TESS) object of interest TOI-519 b. Methods: Our analysis uses a SPOC-pipeline TESS light curve from Sector 7, multicolour transit photometry observed with MuSCAT2 and MuSCAT, and transit photometry observed with the LCOGT telescopes. We estimated the radius of the transiting object using multicolour transit modelling, and we set upper limits for its mass, effective temperature, and Bond albedo using a phase curve model that includes Doppler boosting, ellipsoidal variations, thermal emission, and reflected light components. Results: TOI-519 b is a substellar object with a radius posterior median of 1.07 RJup and 5th and 95th percentiles of 0.66 and 1.20 RJup, respectively, where most of the uncertainty comes from the uncertainty in the stellar radius. The phase curve analysis sets an upper effective temperature limit of 1800 K, an upper Bond albedo limit of 0.49, and a companion mass upper limit of 14 MJup. The companion radius estimate combined with the Teff and mass limits suggests that the companion is more likely a planet than a brown dwarf, but a brown-dwarf scenario is a priori more likely given the lack of known massive planets in 1 day orbits around M dwarfs with Teff < 3800 K, and given the existence of some (but few) brown dwarf

    TOI-519 b: A short-period substellar object around an M dwarf validated using multicolour photometry and phase curve analysis

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    Context. We report the discovery of TOI-519 b (TIC 218795833), a transiting substellar object (R = 1.07 RJup) orbiting a faint M dwarf (V = 17.35) on a 1.26 d orbit. Brown dwarfs and massive planets orbiting M dwarfs on short-period orbits are rare, but more have already been discovered than expected from planet formation models. TOI-519 is a valuable addition to this group of unlikely systems, and it adds towards our understanding of the boundaries of planet formation. Aims. We set out to determine the nature of the Transiting Exoplanet Survey Satellite (TESS) object of interest TOI-519 b. Methods. Our analysis uses a SPOC-pipeline TESS light curve from Sector 7, multicolour transit photometry observed with MuSCAT2 and MuSCAT, and transit photometry observed with the LCOGT telescopes. We estimated the radius of the transiting object using multicolour transit modelling, and we set upper limits for its mass, effective temperature, and Bond albedo using a phase curve model that includes Doppler boosting, ellipsoidal variations, thermal emission, and reflected light components. Results. TOI-519 b is a substellar object with a radius posterior median of 1.07 RJup and 5th and 95th percentiles of 0.66 and 1.20 RJup, respectively, where most of the uncertainty comes from the uncertainty in the stellar radius. The phase curve analysis sets an upper effective temperature limit of 1800 K, an upper Bond albedo limit of 0.49, and a companion mass upper limit of 14 MJup. The companion radius estimate combined with the Teff and mass limits suggests that the companion is more likely a planet than a brown dwarf, but a brown-dwarf scenario is a priori more likely given the lack of known massive planets in ≈ 1 day orbits around M dwarfs with Teff < 3800 K, and given the existence of some (but few) brown dwarfs

    TOI-519 b: A short-period substellar object around an M dwarf validated using multicolour photometry and phase curve analysis

    No full text
    Context. We report the discovery of TOI-519 b (TIC 218795833), a transiting substellar object (R = 1.07 RJup) orbiting a faint M dwarf (V = 17.35) on a 1.26 d orbit. Brown dwarfs and massive planets orbiting M dwarfs on short-period orbits are rare, but more have already been discovered than expected from planet formation models. TOI-519 is a valuable addition to this group of unlikely systems, and it adds towards our understanding of the boundaries of planet formation. Aims. We set out to determine the nature of the Transiting Exoplanet Survey Satellite (TESS) object of interest TOI-519 b. Methods. Our analysis uses a SPOC-pipeline TESS light curve from Sector 7, multicolour transit photometry observed with MuSCAT2 and MuSCAT, and transit photometry observed with the LCOGT telescopes. We estimated the radius of the transiting object using multicolour transit modelling, and we set upper limits for its mass, effective temperature, and Bond albedo using a phase curve model that includes Doppler boosting, ellipsoidal variations, thermal emission, and reflected light components. Results. TOI-519 b is a substellar object with a radius posterior median of 1.07 RJup and 5th and 95th percentiles of 0.66 and 1.20 RJup, respectively, where most of the uncertainty comes from the uncertainty in the stellar radius. The phase curve analysis sets an upper effective temperature limit of 1800 K, an upper Bond albedo limit of 0.49, and a companion mass upper limit of 14 MJup. The companion radius estimate combined with the Teff and mass limits suggests that the companion is more likely a planet than a brown dwarf, but a brown-dwarf scenario is a priori more likely given the lack of known massive planets in ≈ 1 day orbits around M dwarfs with Teff < 3800 K, and given the existence of some (but few) brown dwarfs

    A Coffee Berry Borer (Coleoptera: Curculionidae: Scolytinae) Bibliography

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    Native to Africa, the coffee berry borer, Hypothenemus hampei (Ferrari) (Coleoptera: Curculionidae: Scolytinae), has gradually invaded most coffee-growing areas worldwide. Adult females colonize the coffee berry and oviposit within galleries in the coffee seeds. Larvae and adults consume the seeds, resulting in drastic reductions in yields and quality, negatively affecting the income of approximately 20 million coffee-growing families (~100 million people) in ~80 countries, with losses surpassing more than $500 million annually (Vega et al. 2015). It has become evident that the coffee berry borer scientific community could greatly benefit from having access to a bibliography of the literature related to the insect. Such an information source would allow scientists to find out what research areas have been explored throughout the many coffee berry borer-infested countries after more than 100 years of research on the topic. It could also help to direct lead future research efforts into novel areas, and away from topics and ideas that have been thoroughly investigated in the past

    A Coffee Berry Borer (Coleoptera: Curculionidae: Scolytinae) Bibliography

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    Scientific Contributions of the Mexican Association of Spine Surgeons (Asociación Mexicana de Cirujanos de Columna–AMCICO) to the Global Medical Literature: A 21-Year Systematic Review

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