Dealing with Major Technological Risks

This article is concerned with the management of major hazards stemming from technology and entailing potentially dreadful consequences. It proposes a brief survey of the0501n difficulties and policy issues arising both in public and private decision making when dealing with major technological risks. Three themes are considered: risk assessment, risk sharing and risk control. Issues related to evaluation methods, to risk perception and to the acceptable level of risk are first examined. The article then goes on to explore the problem of optimal risk sharing between the different stakeholders. The firm's liability and extended liability to the firm's partners are considered. Insurance issues are also discussed. Lastly, the survey addresses the control of risks both from a prevention and from a damage mitigation point of view. The various instruments available to the State to reduce risks are reviewed and several issues are also raised with respect to the measures firms can take to reduce risks. Investment in safety, human error, organisational design and information disclosure are addressed in this section. The topics of siting and urban planning are analysed as mitigation strategies, and the important aspect of emergency planning ends the survey. Cet article d'intérêt général porte sur la gestion des risques d'origine technologique aux conséquences potentiellement catastrophiques. Il s'agit d'un document de synthèse destiné à cerner les problèmes fondamentaux en matière de gestion publique et privée des risques technologiques majeurs. Trois thèmes y sont traités: l'évaluation, la distribution et le contrôle des risques. Les questions se rapportant aux méthodes d'évaluation, à la perception des risques et aux difficultés liées à l'établissement d'un seuil de tolérance sont d'abord passées en revue. La seconde partie du document met en lumière les difficultés que présente le partage optimal du risque entre les différents agents. La responsabilité civile de la firme et de ses partenaires est alors examinée. Les problèmes liés à l'assurance contre ce type de risque sont aussi brièvement décrits. Cet article traite enfin du contrôle des risques en couvrant à la fois les approches préventives et les stratégies d'atténuation des dommages. On y aborde premièrement les instruments de contrôle dont dispose l'État pour réduire les risques. Du côté des firmes, les sujets tels que l'investissement en sécurité, l'erreur humaine, le design organisationnel et la divulgation de l'information sont passés en revue. L'aménagement du territoire et la gestion des urgences sont ensuite abordés de façon succincte dans la dernière partie de l'article.Safety, major risks, risk assessment, risk sharing, risk control, prevention, mitigation, Sécurité, risques majeurs, évaluation des risques, distribution des risques, contrôle des risques, prévention, atténuation

L’avenir de la campagne québécoise dans le contexte du nouveau droit de l’aménagement

Le nouveau droit de l'aménagement du territoire au Québec est constitué de deux lois qui s'opposent sur plusieurs points. La loi sur la protection du territoire agricole limite le pouvoir d'aménagement du milieu rural conféré aux MRC par la loi sur l'aménagement et l'urbanisme, tout en entravant les politiques de développement régional et de revitalisation dans les régions périphériques. L'espace rural n'est pas exclusivement un espace agricole: c'est un espace polyvalent et étroitement lié à l'espace urbain. La ruralité québécoise contemporaine nécessite une approche globale et intégrée de l'aménagement du territoire. Ce texte prêche en faveur d'une harmonisation des lois 90 et 125 afin que l'aménagement se fasse aussi à la campagne.Current zoning legislation in Québec is embodied in two laws which contradict one another on several points. The agricultural lands protection law limits the zoning powers of regional municipal authorities in rural areas and hampers regional development policies in peripheral areas. A rural milieu is not strictly synonymous with agriculture. It is rather a multiple-use area with close ties to urban areas. Modem Québec rural environments require a global approach to integrated planning. This paper advocates coordination of laws 90 and 125 to this end

Depression and health-adjusted life expectancy in the Canadian adult population: a descriptive study

Background: Few studies have evaluated the overall population health-related impact of depression in terms of losses to both premature mortality and health-related quality of life (HRQL). Purpose: To estimate health-adjusted life expectancy (HALE) for Canadian adults according to depression status

Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation.

GWAS have identified a breast cancer susceptibility locus on 2q35. Here we report the fine mapping of this locus using data from 101,943 subjects from 50 case-control studies. We genotype 276 SNPs using the 'iCOGS' genotyping array and impute genotypes for a further 1,284 using 1000 Genomes Project data. All but two, strongly correlated SNPs (rs4442975 G/T and rs6721996 G/A) are excluded as candidate causal variants at odds against >100:1. The best functional candidate, rs4442975, is associated with oestrogen receptor positive (ER+) disease with an odds ratio (OR) in Europeans of 0.85 (95% confidence interval=0.84-0.87; P=1.7 × 10(-43)) per t-allele. This SNP flanks a transcriptional enhancer that physically interacts with the promoter of IGFBP5 (encoding insulin-like growth factor-binding protein 5) and displays allele-specific gene expression, FOXA1 binding and chromatin looping. Evidence suggests that the g-allele confers increased breast cancer susceptibility through relative downregulation of IGFBP5, a gene with known roles in breast cell biology

Evidence for the h_b(1P) meson in the decay Upsilon(3S) --> pi0 h_b(1P)

Using a sample of 122 million Upsilon(3S) events recorded with the BaBar detector at the PEP-II asymmetric-energy e+e- collider at SLAC, we search for the $h_b(1P)$ spin-singlet partner of the P-wave chi_{bJ}(1P) states in the sequential decay Upsilon(3S) --> pi0 h_b(1P), h_b(1P) --> gamma eta_b(1S). We observe an excess of events above background in the distribution of the recoil mass against the pi0 at mass 9902 +/- 4(stat.) +/- 2(syst.) MeV/c^2. The width of the observed signal is consistent with experimental resolution, and its significance is 3.1sigma, including systematic uncertainties. We obtain the value (4.3 +/- 1.1(stat.) +/- 0.9(syst.)) x 10^{-4} for the product branching fraction BF(Upsilon(3S)-->pi0 h_b) x BF(h_b-->gamma eta_b).Comment: 8 pages, 4 postscript figures, submitted to Phys. Rev. D (Rapid Communications

Search for squarks and gluinos in events with isolated leptons, jets and missing transverse momentum at s√=8 TeV with the ATLAS detector

The results of a search for supersymmetry in final states containing at least one isolated lepton (electron or muon), jets and large missing transverse momentum with the ATLAS detector at the Large Hadron Collider are reported. The search is based on proton-proton collision data at a centre-of-mass energy s√=8 TeV collected in 2012, corresponding to an integrated luminosity of 20 fb−1. No significant excess above the Standard Model expectation is observed. Limits are set on supersymmetric particle masses for various supersymmetric models. Depending on the model, the search excludes gluino masses up to 1.32 TeV and squark masses up to 840 GeV. Limits are also set on the parameters of a minimal universal extra dimension model, excluding a compactification radius of 1/R c = 950 GeV for a cut-off scale times radius (ΛR c) of approximately 30

Measurement of the cross-section and charge asymmetry of WW bosons produced in proton-proton collisions at s=8\sqrt{s}=8 TeV with the ATLAS detector

This paper presents measurements of the $W^+ \rightarrow \mu^+\nu$ and $W^- \rightarrow \mu^-\nu$ cross-sections and the associated charge asymmetry as a function of the absolute pseudorapidity of the decay muon. The data were collected in proton--proton collisions at a centre-of-mass energy of 8 TeV with the ATLAS experiment at the LHC and correspond to a total integrated luminosity of 20.2~\mbox{fb^{-1}}. The precision of the cross-section measurements varies between 0.8% to 1.5% as a function of the pseudorapidity, excluding the 1.9% uncertainty on the integrated luminosity. The charge asymmetry is measured with an uncertainty between 0.002 and 0.003. The results are compared with predictions based on next-to-next-to-leading-order calculations with various parton distribution functions and have the sensitivity to discriminate between them.Comment: 38 pages in total, author list starting page 22, 5 figures, 4 tables, submitted to EPJC. All figures including auxiliary figures are available at https://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/STDM-2017-13

Evidence for the Higgs-boson Yukawa coupling to tau leptons with the ATLAS detector

Results of a search for H → τ τ decays are presented, based on the full set of proton-proton collision data recorded by the ATLAS experiment at the LHC during 2011 and 2012. The data correspond to integrated luminosities of 4.5 fb−1 and 20.3 fb−1 at centre-of-mass energies of √s = 7 TeV and √s = 8 TeV respectively. All combinations of leptonic (τ → `νν¯ with ` = e, µ) and hadronic (τ → hadrons ν) tau decays are considered. An excess of events over the expected background from other Standard Model processes is found with an observed (expected) significance of 4.5 (3.4) standard deviations. This excess provides evidence for the direct coupling of the recently discovered Higgs boson to fermions. The measured signal strength, normalised to the Standard Model expectation, of µ = 1.43 +0.43 −0.37 is consistent with the predicted Yukawa coupling strength in the Standard Model

Measurement of χ c1 and χ c2 production with s√ = 7 TeV pp collisions at ATLAS

The prompt and non-prompt production cross-sections for the χ c1 and χ c2 charmonium states are measured in pp collisions at s√ = 7 TeV with the ATLAS detector at the LHC using 4.5 fb−1 of integrated luminosity. The χ c states are reconstructed through the radiative decay χ c → J/ψγ (with J/ψ → μ + μ −) where photons are reconstructed from γ → e + e − conversions. The production rate of the χ c2 state relative to the χ c1 state is measured for prompt and non-prompt χ c as a function of J/ψ transverse momentum. The prompt χ c cross-sections are combined with existing measurements of prompt J/ψ production to derive the fraction of prompt J/ψ produced in feed-down from χ c decays. The fractions of χ c1 and χ c2 produced in b-hadron decays are also measured