Multi-objective optimisation of bio-based thermal insulation materials in building envelopes considering condensation risk

The reduction in energy demand for heating and cooling with insulation materials increases the material related environmental impact. Thus, implementing low embodied energy materials may equilibrate this trade-off. Actual trends in passive house postulate bio-based materials as an alternative to conventional ones. Despite that, the implementation of those insulators should be carried out with a deeper analysis due to their hygroscopic properties. The moisture transfer, the associated condensation risk and the energy consumption for seven biobased materials and polyurethane for a building-like cubicle are analysed. The performance is evaluated combining a software application to model the cubicle (EnergyPlus) and a tool to optimize its performance (jEPlus). The novelty of this optimization approach is to include and evaluate the effects of moisture in these insulation materials, taking into account the mass transfer through the different layers and the evaporation of the different materials. This methodology helps optimise the insulation type and thickness verifying the condensation risk, preventing the deterioration of the materials. The total cost of the different solutions is quantified, and the environmental impact is determined using the life cycle assessment methodology. The effect of climate conditions and the envelope configuration, as well as the risk of condensation, are quantified. The results show that cost and environmental impact can be reduced if bio-based materials are used instead of conventional ones, especially in semiarid climates. Condensation risk occurs for large thicknesses and in humid climates. In our case studies, hemp offered the most balanced solution.The authors would like to acknowledge financial support from the Spanish Government (CTQ2016-77968-C3-1-P, ENE2015-64117-C5-1-R, ENE2015-64117-C5-3-R, MINECO/FEDER, UE). The research leading to these results has received funding from the European Commission Seventh Framework Programme under grant agreement no. PIRSES-GA-2013-610692 (INNOSTORAGE). This project has received funding the European Union's Horizon 2020 Research and Innovation Program under grant agreement No 657466 (INPATH-TES). This article has been possible with the support of the Ministerio de Economía y Competitividad (MINECO) and the Universitat Rovira i Virgili (URV) (FJCI-2016-28789). Authors would like to acknowledge the Brazilian Government for their support by the CNPq (National Council for Scientific and Technological Development). M.P. would like to thank the Brazilian Education Ministry for the financial support received under the PNPD/Capes fellowship. L.F.C. would like to thank the Catalan Government for the quality accreditation given to her research group GREA (2014 SGR 123)

Self-consumption possibilities by rooftop PV and building retrofit requirements for a regional building stock: The case of Catalonia

European Union policies are encouraging the implementation of renewable energies to reduce fossil fuels dependency. This is further motivated by the effects of global warming and the relevant temperature rise in large cities. Thus, it is increasingly important to analyze the large-scale potential of solar energy, making use of the roof availability for renewable energy generation in cities. Furthermore, it is important to couple this analysis with the energy demand of the buildings analyzing the self-consumption possibilities and help in the decision-making process in regional investments. The proposed methodology estimates and matches the roof potential for electricity generation by PV and the building's energy demand, including the building characteristics as a novelty. As a result, we calculate the self-consumption possibilities and the retrofit requirements of a selected housing stock. Our methodology starts with the quantification and classification of the residential stock. This includes the characterization of the types of dwellings in the regional residential stock, taking into account the size of the municipalities. Then the energy demand of the dwellings, depending on the characteristics of the buildings and the roof generation potential, is compared. Catalonia region (Spain), including the city of Barcelona is studied to show the contributions of this methodology to the energy transition. Results indicate that between 8 and 30% of the residential electricity demand of the municipalities can be covered by rooftop PV. Important energy retrofits (reductions of 80% of the energy demand) are required to approach the feasibility of self-consumption. Nevertheless, there is a limited potential impact in larger cities due to the reduced available roof area per habitant.Peer ReviewedPostprint (published version

Large-scale evaluation of shotgun triacylglycerol profiling for the fast detection of olive oil adulteration

Fast and effective analytical screening tools providing new suitable authenticity markers and applicable to a large number of samples are required to efficiently control the global olive oil (OO) production, and allow the rapid detection of low levels of adulterants even with fatty acid composition similar to OO. The present study aims to develop authentication models for the comprehensive detection of illegal blends of OO with adulterants including different types of high linoleic (HL) and high oleic (HO) vegetable oils at low concentrations (2-10%) based on shotgun triacylglycerol (TAG) profile obtained by Flow Injection Analysis-Heated Electrospray Ionisation-High Resolution Mass Spectrometry (FIA-HESI-HRMS) at a large-scale experimental design. The sample set covers a large natural variability of both OO and adulterants, resulting in more than one thousand samples analysed. A combined PLS-DA binary modelling based on shotgun TAG profiling proved to be a fit for purpose screening tool in terms of efficiency and applicability. The external validation resulted in the correct classification of the 86.8% of the adulterated samples (diagnostic sensitivity = 0.87), and the 81.1% of the genuine samples (diagnostic specificity = 0.81), with an 85.1% overall correct classification (efficiency = 0.85)

Large-scale evaluation of shotgun triacylglycerol profiling for the fast detection of olive oil adulteration

Final version is available in open access in publisher’s site.-- This abstract is based on the published article: Beatriz Quintanilla-Casas, Giulia Strocchi, Julen Bustamante, Berta Torres-Cobos, Francesc Guardiola, Wenceslao Moreda, José Manuel Martínez-Rivas, Enrico Valli, Alessandra Bendini, Tullia Gallina Toschi, Alba Tres, Stefania Vichi. Large-scale evaluation of shotgun triacylglycerol profiling for the fast detection of olive oil adulteration. Food Control, Volume 123, 2021, 107851, https://doi.org/10.1016/j.foodcont.2020.107851.-- http://hdl.handle.net/10261/229187Peer reviewe

The urban project. The end of degree project

Ésta es una publicación que explica nuestra experien¬cia docente en la invención de estrategias para el territorio urbano, basadas en el proyecto como instrumento de in¬tervención; un método que presenta características de los planes a la vez que de los proyectos arquitectónicos, con ideas que van más allá del artefacto que proponen y del lugar estricto en que se implantan. Comoquiera que este libro se dedica a presentar los pro¬yectos fin de carrera de los estudiantes de Arquitectura que han elegido elaborar propuestas que siguen esta línea arquitectónico-urbanística. Desde nuestra joven Escuela de Arquitectura de Granada, quisiéramos ver arraigar y desarrollar algunos de los atributos que se presentanen el prólogo de Joan Busquets, destacado urbanista y pro¬fesor. Obviamente, la generosa autoriza-ción para publicar este texto, quiere significar para noso¬tros, y así lo sugerimos a nuestros alumnos y lectores, una referencia de calidad para seguir profundizando y mejoran¬do en el camino emprendido. Que no es otro que el empeño de contribuir al bienestar más igualitario de los ciudadanos en los territorios en que transcurren sus vidas. The implication of the University in the problems of the so¬ciety and the territory of its environment and of its time, constitutes a major exigency more the university institution spreads toal most all the cities of our country, all more cons¬cience is of that the knowledge is an essential vector of our time and major they are the requirements of innovation to face the emergent problems of extensive urbanization and environmental deterioration. Thisuniversitycommitmentwithitsenviromentissufficientlyrecognizedwhenonespeaksaboutinvestigation but is re comforting also to recognize it in educational efforts like that here we preface. The teaching is formation of human resources and frame of possible confluence of universal concepts with the local conditions. To the margin of this confrontation of generic values with a few historical - social precise and local needs, those resources would not conform as share capital, as so¬lidary with a collective project. In these publications of the a Area of Urban development and Land management of one of its years in the Technical Top School of Architecture, it is necessary to admit this effort of commitment between the global thing and the lo¬cal thing, between the knowledge and the practice, between culture and society. It is necessary to recognize, to support its continuity and contagious diffusion it and it be grateful to all by those, teachers and pupils, who have collaborated both in the curses and in the publications.Junta de Andalucía y Universidad de Granad

Spread of a SARS-CoV-2 variant through Europe in the summer of 2020.

Following its emergence in late 2019, the spread of SARS-CoV-21,2 has been tracked by phylogenetic analysis of viral genome sequences in unprecedented detail3–5. Although the virus spread globally in early 2020 before borders closed, intercontinental travel has since been greatly reduced. However, travel within Europe resumed in the summer of 2020. Here we report on a SARS-CoV-2 variant, 20E (EU1), that was identified in Spain in early summer 2020 and subsequently spread across Europe. We find no evidence that this variant has increased transmissibility, but instead demonstrate how rising incidence in Spain, resumption of travel, and lack of effective screening and containment may explain the variant’s success. Despite travel restrictions, we estimate that 20E (EU1) was introduced hundreds of times to European countries by summertime travellers, which is likely to have undermined local efforts to minimize infection with SARS-CoV-2. Our results illustrate how a variant can rapidly become dominant even in the absence of a substantial transmission advantage in favourable epidemiological settings. Genomic surveillance is critical for understanding how travel can affect transmission of SARS-CoV-2, and thus for informing future containment strategies as travel resumes. © 2021, The Author(s), under exclusive licence to Springer Nature Limited

The evolution of the ventilatory ratio is a prognostic factor in mechanically ventilated COVID-19 ARDS patients

Background: Mortality due to COVID-19 is high, especially in patients requiring mechanical ventilation. The purpose of the study is to investigate associations between mortality and variables measured during the first three days of mechanical ventilation in patients with COVID-19 intubated at ICU admission. Methods: Multicenter, observational, cohort study includes consecutive patients with COVID-19 admitted to 44 Spanish ICUs between February 25 and July 31, 2020, who required intubation at ICU admission and mechanical ventilation for more than three days. We collected demographic and clinical data prior to admission; information about clinical evolution at days 1 and 3 of mechanical ventilation; and outcomes. Results: Of the 2,095 patients with COVID-19 admitted to the ICU, 1,118 (53.3%) were intubated at day 1 and remained under mechanical ventilation at day three. From days 1 to 3, PaO2/FiO2 increased from 115.6 [80.0-171.2] to 180.0 [135.4-227.9] mmHg and the ventilatory ratio from 1.73 [1.33-2.25] to 1.96 [1.61-2.40]. In-hospital mortality was 38.7%. A higher increase between ICU admission and day 3 in the ventilatory ratio (OR 1.04 [CI 1.01-1.07], p = 0.030) and creatinine levels (OR 1.05 [CI 1.01-1.09], p = 0.005) and a lower increase in platelet counts (OR 0.96 [CI 0.93-1.00], p = 0.037) were independently associated with a higher risk of death. No association between mortality and the PaO2/FiO2 variation was observed (OR 0.99 [CI 0.95 to 1.02], p = 0.47). Conclusions: Higher ventilatory ratio and its increase at day 3 is associated with mortality in patients with COVID-19 receiving mechanical ventilation at ICU admission. No association was found in the PaO2/FiO2 variation

Mitochondrial physiology

As the knowledge base and importance of mitochondrial physiology to evolution, health and disease expands, the necessity for harmonizing the terminology concerning mitochondrial respiratory states and rates has become increasingly apparent. The chemiosmotic theory establishes the mechanism of energy transformation and coupling in oxidative phosphorylation. The unifying concept of the protonmotive force provides the framework for developing a consistent theoretical foundation of mitochondrial physiology and bioenergetics. We follow the latest SI guidelines and those of the International Union of Pure and Applied Chemistry (IUPAC) on terminology in physical chemistry, extended by considerations of open systems and thermodynamics of irreversible processes. The concept-driven constructive terminology incorporates the meaning of each quantity and aligns concepts and symbols with the nomenclature of classical bioenergetics. We endeavour to provide a balanced view of mitochondrial respiratory control and a critical discussion on reporting data of mitochondrial respiration in terms of metabolic flows and fluxes. Uniform standards for evaluation of respiratory states and rates will ultimately contribute to reproducibility between laboratories and thus support the development of data repositories of mitochondrial respiratory function in species, tissues, and cells. Clarity of concept and consistency of nomenclature facilitate effective transdisciplinary communication, education, and ultimately further discovery

Repositioning of the global epicentre of non-optimal cholesterol

High blood cholesterol is typically considered a feature of wealthy western countries(1,2). However, dietary and behavioural determinants of blood cholesterol are changing rapidly throughout the world(3) and countries are using lipid-lowering medications at varying rates. These changes can have distinct effects on the levels of high-density lipoprotein (HDL) cholesterol and non-HDL cholesterol, which have different effects on human health(4,5). However, the trends of HDL and non-HDL cholesterol levels over time have not been previously reported in a global analysis. Here we pooled 1,127 population-based studies that measured blood lipids in 102.6 million individuals aged 18 years and older to estimate trends from 1980 to 2018 in mean total, non-HDL and HDL cholesterol levels for 200 countries. Globally, there was little change in total or non-HDL cholesterol from 1980 to 2018. This was a net effect of increases in low- and middle-income countries, especially in east and southeast Asia, and decreases in high-income western countries, especially those in northwestern Europe, and in central and eastern Europe. As a result, countries with the highest level of non-HDL cholesterol-which is a marker of cardiovascular riskchanged from those in western Europe such as Belgium, Finland, Greenland, Iceland, Norway, Sweden, Switzerland and Malta in 1980 to those in Asia and the Pacific, such as Tokelau, Malaysia, The Philippines and Thailand. In 2017, high non-HDL cholesterol was responsible for an estimated 3.9 million (95% credible interval 3.7 million-4.2 million) worldwide deaths, half of which occurred in east, southeast and south Asia. The global repositioning of lipid-related risk, with non-optimal cholesterol shifting from a distinct feature of high-income countries in northwestern Europe, north America and Australasia to one that affects countries in east and southeast Asia and Oceania should motivate the use of population-based policies and personal interventions to improve nutrition and enhance access to treatment throughout the world.Peer reviewe