12 research outputs found
Alineamiento estratégico:ajustes en la estructura organizacional y diseño de mapa de procesos en una ONG orientada a salud
- Publication venue
- 'Baishideng Publishing Group Inc.'
- Publication date
- 03/10/2011
- Field of study
La presente tesis trata de la alineación estratégica (que la estrategia
desarrollada se vea reflejada en su organización), de una Institución sin fines
de Lucro (ONG) que trabaja en el sector salud por más de 20 años y es de
reconocido prestigio en el sector donde se desarrolla: atención medica,
laboratorio, investigación y gestión de proyectos y programas sociales.
Esta alineación se basa en los tres elementos claves de toda organización:
Estrategia, Estructura y Procesos, donde estas últimas se construyen en
base a la estrategia definida, para ello se diseñan o rediseñan los
instrumentos macros esenciales para la gestión: La estructura
Organizacional (Organigrama) y el Mapa de Procesos.
Para el logro de este objetivo, se utiliza metodologías plasmadas por
Huaman y Rios (2008), donde el diseño de la estructura organizacional está
basada en la metodología de los autores Vigo y Segura, mientras
metodología del diseño del Mapa de Procesos esta basada su construcción
en la cadena de Valor de Michael Porter.
Para el diseño de una estructura organizacional, se revisó el plan estratégico
vigente de la institución, con énfasis en sus estrategias corporativas y de
negocios, y su despliegue basado en objetivos (¿qué quiero?) y actividades
(¿cómo lo consigo?); y es con estas últimas con las que se trabaja para la
formación de la estructura, pasando cada una de estas, por un análisis de
sensibilidad con el logro del objetivo (nivel de jerarquía) y un análisis de
relaciones entre ellas (especialización).
Para el diseño del mapa de procesos se comenzó con las 3 preguntas
básicas: ¿qué hace la organización? definiendo sus productos, ¿para quien?
Definiendo sus clientes, y ¿Cómo lo hace?, definiendo sus procesos, y es
con este ultimo que basado en las actividades, se usa la cadena de valor
para esquematizarlo, y luego generar el Mapa de Procesos.
iii
Toda esta metodología se realizo en base a talleres y reuniones con los
directivos, en el cual se tomaron decisiones de diseño relevantes para la
definición de los instrumentos.
El resultado obtenido fue la modificación de la estructura organizacional
actual, eliminando áreas, mejorando la especialización del conocimiento y la
integración del trabajo. También se creó el mapa de Procesos, donde quedo
en evidencia la gran cantidad de actividades que realiza la organización,
generando la eliminando de algunas que no generaban valor, así con el
cambio de foco del personal interno, que estaban orientados a la tarea, y no
a los resultados.Tesi
Canagliflozin and renal outcomes in type 2 diabetes and nephropathy
- Author
- A Kaldun Nossuli
- Aamir Jamal
- Adalbert Schiller
- Adam Cheifetz
- Adarsh Daswani
- Adeera Levin
- Adline Ghazi
- Adrian Guinsburg
- Adriana Cif
- Adriana Gabriela Onaca
- Adriana Ilavska
- Adriana Villarino
- Agarwal R.
- Agnieszka Starzec
- Ahmed Arif
- Ahmed Awad
- Aiping Yin
- Akimichi Asano
- Alan Jackson
- Alan McMahon
- Alan Perlman
- Alberto Di Carlo
- Alberto Esquenazi
- Alejandra Oviedo
- Alejandro Valdes Depeda
- Aleksandra Kendereski
- Alex Valenzuela
- Alexander Dreval
- Alexander Gonzalez
- Alexander Shinkov
- Alexander Turchin
- Alexandre Klein
- Alfonso Soto Gonzalez
- Alfred Penfornis
- Alfredo Chew Wong
- Alfredo Wassermann
- Ali Torshizi
- Alicia Chilito
- Alina Agafyina
- Alison Dawson
- Alva Hansraj
- Amer Al-Karadsheh
- Amorin Remus Popa
- Amrendra Kumar
- Amy Sprague
- Ana Limos
- Ana Maria Cusumano
- Ana Maria Elosegui
- Anabella Amigo
- Anatoliy Kazmirchuk
- Andrea Phillips
- Andrea Stella
- Andreas Maddux
- Andrej Dzupina
- Andres Alvarisqueta
- Andrew Johnson
- Andrew O'Shaughnessy
- Andrew Steele
- Andrian Yakov
- Andrzej Januszewicz
- Andrzej Madej
- Angelina Angelova
- Anibal Gastaldi
- Anil Gupta
- Anita Bhajan Manocha
- Anjanette Tan
- Anna Kaminska
- Anna Maria Veronelli
- Anna Strzelecka
- Anna Zateyshchikova
- Anselmo Bordonava
- Antanas Navickas
- Anthony Gunstone
- Anthony Roberts
- Antonio Ceriello
- Antonio Galan Serrano
- Antonio Scafuto Scotton
- Antonio Terrelonge
- Antônio Roberto Chacra
- Anupama Gowda
- Arjun D Sinha
- Armando Perez
- Ashot Mkrtumyan
- Atanas Koundurdjiev
- Augusto Vallejos
- Aurelian-Emil Ranetti
- Ayim Akyea-Djamson
- Aysha Badat
- Bakris G.
- Baldev Singh
- Barbara Greco
- Barbara Kaczmarek
- Barbara Rewerska
- Barry M Brenner
- Belia Martin Del Camp Blanco
- Bernard Zinman
- Bertrand Cariou
- Bertrand Dussol
- Bhasker Mehta
- Bhimavarapu Sudhakar
- Björn Paschen
- Bompoint S.
- Borys Mankovskyy
- Botond Csiky
- Boyan Nonchev
- Brenner B. M.
- Brett Kissela
- Brian Nichol
- Bruce Neal
- Bruce Trippe
- Bruno Geloneze Neto
- Bull S.
- Byung-Wan Lee
- C B Keshavamurthy
- Cannon C. P.
- Capuano G.
- Carlo Giorda
- Carlos Alberto Cuneo
- Carlos Arauz-Pacheco
- Carlos Barrera
- Carlos Perez
- Carmel Hawley
- Carmen Crisan
- Carol Pollock
- Carolyn Droste
- Caroucel Chuateco
- Caryl David
- Cecilia Garcia Ballesteros
- Cecilia Jimeno
- Celso Amodeo
- Cesar Javier Zaidman
- Cesar Yoiti Hayashida
- Chamberlain Obialo
- Chang-Hsun Hsieh
- Charles Cook
- Charles Kaupke
- Charytan D. M.
- Chek Loong Loh
- Chen Leia
- Cheol-Young Park
- Chih-Ching Lin
- Christopher P Cannon
- Christy Yao
- Chu P. -L.
- Chwen-Tzuei Chang
- Chye Lee Gan
- Clara Barrios
- Claude Galphin
- Claudia Goycoa
- Claudia Moreira de Brito
- Clodoaido Caringal
- Cristian Serafinceanu
- Cristina Toarba
- Cristobal Morales Portillo
- Csaba Kovesdy
- Cynthia Bowman-Stroud
- Cynthia Christiano
- Cynthia Mustieles Rocha
- Cyrus Desouza
- Cássio Slompo Ramos
- Dagmar Bartaskova
- Dale Crawford Allison
- Dalia Kozloviene
- Dan Scharfstein
- Dana Cosma
- Daniel Coyne
- Daniel Hiser
- Daniel Kolansky
- Daniel Panarotto
- Daniel Pella
- Daniel Weiner
- Daniil Chizhov
- Dariusz Sowinski
- Darren K McGuire
- Davesh Sennik
- David C Wheeler
- David Cherney 3rd
- David Gorson
- David Johnson
- David M Charytan
- David Packham
- David Scott
- David Wheeler
- De Zeeuw D.
- Debbie Cohen-Stein
- Debbie Mascaro
- Deepak Koppolu
- Dennis Levinson
- Derek Lewis
- Detian Li
- Devasmita Dev
- Devesh Patel
- Dewan Deepak
- Dick de Zeeuw
- Diego Aizenberg
- Dinesh Jain
- Dinesh Khullar
- Diogo Belo
- Dmitry Zateyshshikov
- Domenico Santoro
- Domingos d'Avila
- Donald Brandon
- Donald Fraser
- Dong-Wan Chae
- Dora Inés Molina de Salazar
- Dorota Mlodawska-Choluj
- Doru Negru
- Edgar Arcos
- Edoardo Mannucci
- Eduardo Farias
- Edward Watson
- Edwards R.
- Egle Gaupsiene
- Egle Urbanaviciene
- Ekaterina Velichkova
- Elena Christofides
- Elena Grineva
- Elena Kolmakova
- Elena Shutemova
- Eleonora Harcsa
- Elizabeth Barranco
- Elizabeth Gelersztein
- Elizabeth Kern
- Elizete Keitel
- Eloisa Tellez Chavez
- Emanuela Orsi
- Emil Martinka
- Emyr Davies
- Enrique Gonzalez
- Eric Alamartine
- Eric Hernandez Triana
- Eric Thervet
- Erick Turcios Juarez
- Esteban Cercos
- Eugenia Galindo-Ramos
- Eva Peterfai
- Evaly Chen
- Evandro de Souza Portes
- Evgueniy Vazelov
- Fabian Otreras
- Fabiana Loss de Carvalho Contieri
- Fabio Malberti
- Fadi Saba
- Fadlo Fraige Filho
- Favio Edmundo Enriquez Sosa
- Fayzal Ahmed
- Ferdinando Carlo Sasso
- Fernanco Augusto Alves da Costa
- Fernanda Cristina Camelo Sanches
- Fernando Cereto Castro
- Fernando Flores Lozano
- Fernando Jimenez Florez
- Fernando Krynski
- Fernando M Edwin
- Fernando Thomé
- Fernando Trespalacios
- Florence Santos
- Florencia Kraft
- Fracisco Javier Gonzalez Martinez
- Fran Morren
- Franciso Jose Tinahones Madueno
- Frank Eder
- Franklin Joseph
- Franklin Paul Haase
- Frantisek Saudek
- François Dubé
- François Madore
- Freemu Varghese
- Gabriela Cecilia Coloma
- Gabriela Genova-Hristova
- Gabriele von Ingersleben
- Gaetano Serviddio
- Galina Nagibovich
- Gary Meininger
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- Georg Plassmann
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- George Newman
- Gerald DaRoza
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- Giacomo Garibotto
- Giorgio Fuiano
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- Giovanni Gambaro
- Giuseppe Derosa
- Gizella Petro
- Glenn Chertow
- Gnyandev Patel
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- Grace Aquitania
- Grace Lin
- Graham Hillis
- Graziano Di Cianni
- Grazyna Orlowska-Kowalik
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- Greg Fulcher
- Gregorio Obrador
- Gregorio Obrador Vera
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- Guadalupe Morales Franco
- Guillermo Fragale
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- Gulam Latiff
- Gustavo Cristian Greloni
- Guy Chouinard
- Gyongyi Csecsei
- Gyorgy Paragh
- Halyna Tomashkevych
- Hans Prozesky
- Harpreet Bajaj
- Hasnain Khandwala
- Hector Rodriguez
- Heerspink H. J. L.
- Helena Oosthuizen
- Hendrik Nortje
- Henry Watson
- Hermann Haller
- Hernan Finkelstein
- Hernan Yupanqui
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- Hiralal Maheshwari
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- Hiroshi Kono
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- Meg Jardine
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- Melchor Alpizar Salazar
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- Vira Tseluyko
- Virginia Esther Visco
- Vivek Sood
- Vivekan Jha
- Vladimir Dobronravov
- Vladimir Khirmanov
- Vladimir Tesar
- Vlado Perkovic
- Volker Burst
- Volodymyr Botsyurko
- Walter Guillermo Douthat
- Walter Pharr
- Wasim Hanif
- Wataru Yumita
- Wayne H-H Sheu
- Wayne Turner
- Wei Yen Kong
- Weihong Song
- Weiping Lu
- Wendy Lane
- Wenge Li
- Wheeler D. C.
- Wladmir Saporito
- Xuemei Li
- Xueqing Yu
- Yamil Canaan
- Yan Ren
- Yannick Le Meur
- Yaozhong Kong
- Yasuro Kumeda
- Yasushi Wakida
- Yavin Y.
- Yeong Hoon Kim
- Yevgeniya Svyshchenko
- Young Min Cho
- Yulia Samoylova
- Yung-Chuan Lu
- Yuriy Mostovoy
- Yuriy Shwartz
- Yvette Ethel Yap
- Zaynab Abejuela
- Zdravko Kamenov
- Zeid Khitan
- Zhang H.
- Zinman B.
- Zishan Ali
- Zuzana Ochodnicka
- Ângela Regina Nazario Sabbag
- Publication venue
- 'Massachusetts Medical Society'
- Publication date
- 01/01/2019
- Field of study
BACKGROUND Type 2 diabetes mellitus is the leading cause of kidney failure worldwide, but few effective long-term treatments are available. In cardiovascular trials of inhibitors of sodium–glucose cotransporter 2 (SGLT2), exploratory results have suggested that such drugs may improve renal outcomes in patients with type 2 diabetes. METHODS In this double-blind, randomized trial, we assigned patients with type 2 diabetes and albuminuric chronic kidney disease to receive canagliflozin, an oral SGLT2 inhibitor, at a dose of 100 mg daily or placebo. All the patients had an estimated glomerular filtration rate (GFR) of 30 to <90 ml per minute per 1.73 m2 of body-surface area and albuminuria (ratio of albumin [mg] to creatinine [g], >300 to 5000) and were treated with renin–angiotensin system blockade. The primary outcome was a composite of end-stage kidney disease (dialysis, transplantation, or a sustained estimated GFR of <15 ml per minute per 1.73 m2), a doubling of the serum creatinine level, or death from renal or cardiovascular causes. Prespecified secondary outcomes were tested hierarchically. RESULTS The trial was stopped early after a planned interim analysis on the recommendation of the data and safety monitoring committee. At that time, 4401 patients had undergone randomization, with a median follow-up of 2.62 years. The relative risk of the primary outcome was 30% lower in the canagliflozin group than in the placebo group, with event rates of 43.2 and 61.2 per 1000 patient-years, respectively (hazard ratio, 0.70; 95% confidence interval [CI], 0.59 to 0.82; P=0.00001). The relative risk of the renal-specific composite of end-stage kidney disease, a doubling of the creatinine level, or death from renal causes was lower by 34% (hazard ratio, 0.66; 95% CI, 0.53 to 0.81; P<0.001), and the relative risk of end-stage kidney disease was lower by 32% (hazard ratio, 0.68; 95% CI, 0.54 to 0.86; P=0.002). The canagliflozin group also had a lower risk of cardiovascular death, myocardial infarction, or stroke (hazard ratio, 0.80; 95% CI, 0.67 to 0.95; P=0.01) and hospitalization for heart failure (hazard ratio, 0.61; 95% CI, 0.47 to 0.80; P<0.001). There were no significant differences in rates of amputation or fracture. CONCLUSIONS In patients with type 2 diabetes and kidney disease, the risk of kidney failure and cardiovascular events was lower in the canagliflozin group than in the placebo group at a median follow-up of 2.62 years
Measuring progress from 1990 to 2017 and projecting attainment to 2030 of the health-related Sustainable Development Goals for 195 countries and territories: a systematic analysis for the Global Burden of Disease Study 2017
- Author
- Abate Degu
- Abay Solomon M
- Abbafati Cristiana
- Abbasi Nooshin
- Abbastabar Hedayat
- Abd-Allah Foad
- Abdel-Rahman Omar
- Abdela Jemal
- Abdelalim Ahmed
- Abdi Alireza
- Abdollahpour Ibrahim
- Abdulkader Rizwan Suliankatchi
- Abebe Nebiyu Dereje
- Abebe Zegeye
- Abejie Ayenew Negesse
- Abera Semaw F
- Abil Olifan Zewdie
- Aboyans Victor
- Abraha Haftom Niguse
- Abrham Aklilu Roba
- Abu-Raddad Laith Jamal
- Abu-Rmeileh Niveen Me
- Abyu Gebre Y
- Accrombessi Manfred Mario Kokou
- Acharya Dilaram
- Acharya Pawan
- Adamu Abdu A
- Adebayo Oladimeji M
- Adedeji Isaac Akinkunmi
- Adedoyin Rufus Adesoji
- Adekanmbi Victor
- Adetokunboh Olatunji O
- Adhena Beyene Meressa
- Adhikari Tara Ballav
- Adib Mina G
- Adou Arsène Kouablan
- Adsuar Jose C
- Afarideh Mohsen
- Afshari Mahdi
- Afshin Ashkan
- Agarwal Gina
- Aghayan Sargis Aghasi
- Agius Dominic
- Agrawal Anurag
- Agrawal Sutapa
- Ahmadi Alireza
- Ahmadi Mehdi
- Ahmadieh Hamid
- Ahmed Muktar Beshir
- Ahmed Sayem
- Akalu Temesgen Yihunie
- Akanda Ali S
- Akbari Mohammad Esmaeil
- Akibu Mohammed
- Akinyemi Rufus Olusola
- Akinyemiju Tomi
- Akseer Nadia
- Al-Aly Ziyad
- Al-Eyadhy Ayman
- Al-Maskari Fatma
- Al-Mekhlafi Hesham M
- Al-Raddadi Rajaa M
- Alahdab Fares
- Alam Khurshid
- Alam Tahiya
- Albujeer Ammar
- Alebel Animut
- Alene Kefyalew Addis
- Alhabib Samia
- Ali Raghib
- Alijanzadeh Mehran
- Alizadeh-Navaei Reza
- Aljunid Syed Mohamed
- Alkerwi Ala'a
- Alla François
- Allebeck Peter
- Allen Christine A
- Almasi Ali
- Alonso Jordi
- Alsharif Ubai
- Altirkawi Khalid
- Alvis-Guzman Nelson
- Amare Azmeraw T
- Amenu Kebede
- Amini Erfan
- Ammar Walid
- Anber Nahla Hamed
- Anderson Jason A
- Andrei Catalina Liliana
- Androudi Sofia
- Animut Megbaru Debalkie
- Anjomshoa Mina
- Ansari Hossein
- Ansariadi Ansariadi
- Ansha Mustafa Geleto
- Antonio Carl Abelardo T
- Anwari Palwasha
- Appiah Lambert Tetteh
- Aremu Olatunde
- Areri Habtamu Abera
- Arora Monika
- Aryal Krishna K
- Asayesh Hamid
- Asfaw Ephrem Tsegay
- Asgedom Solomon Weldegebreal
- Asghar Rana Jawad
- Assadi Reza
- Ataro Zerihun
- Atique Suleman
- Atre Sachin R
- Atteraya Madhu Sudhan
- Ausloos Marcel
- Avila-Burgos Leticia
- Avokpaho Euripide F G A
- Awasthi Ashish
- Ayala Quintanilla Beatriz Paulina
- Ayele Henok Tadesse
- Ayele Yohanes
- Ayer Rakesh
- Azarpazhooh Mahmoud Reza
- Azzopardi Peter S
- Azzopardi-Muscat Natasha
- Babalola Tesleem Kayode
- Babazadeh Arefeh
- Badali Hamid
- Badawi Alaa
- Balakrishnan Kalpana
- Bali Ayele Geleto
- Banach Maciej
- Banerjee Amitava
- Banoub Joseph Adel Mattar
- Banstola Amrit
- Barac Aleksandra
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- Barker-Collo Suzanne Lyn
- Barrero Lope H
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- Tekalign Tigist Gashaw
- Tekle Merhawi Gebremedhin
- Temesgen Habtamu
- Temsah Mohamad-Hani
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- Teshome Destaw Fetene
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- Whisnant Joanna L
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- Widecka Justyna
- Widecka Katarzyna
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- Wilner Lauren B
- Winkler Andrea Sylvia
- Wiyeh Alison B
- Wiysonge Charles Shey
- Wolde Haileab Fekadu
- Wolfe Charles D A
- Wu Shouling
- Xavier Denis
- Xu Gelin
- Xu Rixing
- Yadollahpour Ali
- Yahyazadeh Jabbari Seyed Hossein
- Yakob Bereket
- Yamada Tomohide
- Yan Lijing L
- Yano Yuichiro
- Yaseri Mehdi
- Yasin Yasin Jemal
- Ye Pengpeng
- Yearwood Jamal A
- Yeshaneh Alex
- Yimer Ebrahim M
- Yip Paul
- Yirsaw Biruck Desalegn
- Yisma Engida
- Yonemoto Naohiro
- Yonga Gerald
- Yoon Seok-Jun
- Yotebieng Marcel
- Younis Mustafa Z
- Yousefifard Mahmoud
- Yu Chuanhua
- Zaman Sojib Bin
- Zamani Mohammad
- Zare Zohreh
- Zavala-Arciniega Luis
- Zegeye Desalegn Tegabu
- Zegeye Elias Asfaw
- Zeleke Ayalew Jejaw
- Zendehdel Kazem
- Zerfu Taddese Alemu
- Zhang Anthony Lin
- Zhang Xueying
- Zhou Maigeng
- Zhu Jun
- Zimsen Stephanie R M
- Zodpey Sanjay
- Zoeckler Leo
- Zucker Inbar
- Zuhlke Liesel Joanna J
- Ärnlöv Johan
- Çavlin Alanur
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2018
- Field of study
Background: Efforts to establish the 2015 baseline and monitor early implementation of the UN Sustainable Development Goals (SDGs) highlight both great potential for and threats to improving health by 2030. To fully deliver on the SDG aim of “leaving no one behind”, it is increasingly important to examine the health-related SDGs beyond national-level estimates. As part of the Global Burden of Diseases, Injuries, and Risk Factors Study 2017 (GBD 2017), we measured progress on 41 of 52 health-related SDG indicators and estimated the health-related SDG index for 195 countries and territories for the period 1990–2017, projected indicators to 2030, and analysed global attainment. Methods: We measured progress on 41 health-related SDG indicators from 1990 to 2017, an increase of four indicators since GBD 2016 (new indicators were health worker density, sexual violence by non-intimate partners, population census status, and prevalence of physical and sexual violence [reported separately]). We also improved the measurement of several previously reported indicators. We constructed national-level estimates and, for a subset of health-related SDGs, examined indicator-level differences by sex and Socio-demographic Index (SDI) quintile. We also did subnational assessments of performance for selected countries. To construct the health-related SDG index, we transformed the value for each indicator on a scale of 0–100, with 0 as the 2\ub75th percentile and 100 as the 97\ub75th percentile of 1000 draws calculated from 1990 to 2030, and took the geometric mean of the scaled indicators by target. To generate projections through 2030, we used a forecasting framework that drew estimates from the broader GBD study and used weighted averages of indicator-specific and country-specific annualised rates of change from 1990 to 2017 to inform future estimates. We assessed attainment of indicators with defined targets in two ways: first, using mean values projected for 2030, and then using the probability of attainment in 2030 calculated from 1000 draws. We also did a global attainment analysis of the feasibility of attaining SDG targets on the basis of past trends. Using 2015 global averages of indicators with defined SDG targets, we calculated the global annualised rates of change required from 2015 to 2030 to meet these targets, and then identified in what percentiles the required global annualised rates of change fell in the distribution of country-level rates of change from 1990 to 2015. We took the mean of these global percentile values across indicators and applied the past rate of change at this mean global percentile to all health-related SDG indicators, irrespective of target definition, to estimate the equivalent 2030 global average value and percentage change from 2015 to 2030 for each indicator. Findings: The global median health-related SDG index in 2017 was 59\ub74 (IQR 35\ub74–67\ub73), ranging from a low of 11\ub76 (95% uncertainty interval 9\ub76–14\ub70) to a high of 84\ub79 (83\ub71–86\ub77). SDG index values in countries assessed at the subnational level varied substantially, particularly in China and India, although scores in Japan and the UK were more homogeneous. Indicators also varied by SDI quintile and sex, with males having worse outcomes than females for non-communicable disease (NCD) mortality, alcohol use, and smoking, among others. Most countries were projected to have a higher health-related SDG index in 2030 than in 2017, while country-level probabilities of attainment by 2030 varied widely by indicator. Under-5 mortality, neonatal mortality, maternal mortality ratio, and malaria indicators had the most countries with at least 95% probability of target attainment. Other indicators, including NCD mortality and suicide mortality, had no countries projected to meet corresponding SDG targets on the basis of projected mean values for 2030 but showed some probability of attainment by 2030. For some indicators, including child malnutrition, several infectious diseases, and most violence measures, the annualised rates of change required to meet SDG targets far exceeded the pace of progress achieved by any country in the recent past. We found that applying the mean global annualised rate of change to indicators without defined targets would equate to about 19% and 22% reductions in global smoking and alcohol consumption, respectively; a 47% decline in adolescent birth rates; and a more than 85% increase in health worker density per 1000 population by 2030. Interpretation: The GBD study offers a unique, robust platform for monitoring the health-related SDGs across demographic and geographic dimensions. Our findings underscore the importance of increased collection and analysis of disaggregated data and highlight where more deliberate design or targeting of interventions could accelerate progress in attaining the SDGs. Current projections show that many health-related SDG indicators, NCDs, NCD-related risks, and violence-related indicators will require a concerted shift away from what might have driven past gains—curative interventions in the case of NCDs—towards multisectoral, prevention-oriented policy action and investments to achieve SDG aims. Notably, several targets, if they are to be met by 2030, demand a pace of progress that no country has achieved in the recent past. The future is fundamentally uncertain, and no model can fully predict what breakthroughs or events might alter the course of the SDGs. What is clear is that our actions—or inaction—today will ultimately dictate how close the world, collectively, can get to leaving no one behind by 2030
Measuring progress from 1990 to 2017 and projecting attainment to 2030 of the health-related Sustainable Development Goals for 195 countries and territories: a systematic analysis for the Global Burden of Disease Study 2017.
- Author
- Abate Degu
- Abay Solomon M
- Abbafati Cristiana
- Abbasi Nooshin
- Abbastabar Hedayat
- Abd-Allah Foad
- Abdel-Rahman Omar
- Abdela Jemal
- Abdelalim Ahmed
- Abdi Alireza
- Abdollahpour Ibrahim
- Abdulkader Rizwan Suliankatchi
- Abebe Nebiyu Dereje
- Abebe Zegeye
- Abejie Ayenew Negesse
- Abera Semaw F
- Abil Olifan Zewdie
- Aboyans Victor
- Abraha Haftom Niguse
- Abrham Aklilu Roba
- Abu-Raddad Laith Jamal
- Abu-Rmeileh Niveen Me
- Abyu Gebre Y
- Accrombessi Manfred Mario Kokou
- Acharya Dilaram
- Acharya Pawan
- Adamu Abdu A
- Adebayo Oladimeji M
- Adedeji Isaac Akinkunmi
- Adedoyin Rufus Adesoji
- Adekanmbi Victor
- Adetokunboh Olatunji O
- Adhena Beyene Meressa
- Adhikari Tara Ballav
- Adib Mina G
- Adou Arsène Kouablan
- Adsuar Jose C
- Afarideh Mohsen
- Afshari Mahdi
- Afshin Ashkan
- Agarwal Gina
- Aghayan Sargis Aghasi
- Agius Dominic
- Agrawal Anurag
- Agrawal Sutapa
- Ahmadi Alireza
- Ahmadi Mehdi
- Ahmadieh Hamid
- Ahmed Muktar Beshir
- Ahmed Sayem
- Akalu Temesgen Yihunie
- Akanda Ali S
- Akbari Mohammad Esmaeil
- Akibu Mohammed
- Akinyemi Rufus Olusola
- Akinyemiju Tomi
- Akseer Nadia
- Al-Aly Ziyad
- Al-Eyadhy Ayman
- Al-Maskari Fatma
- Al-Mekhlafi Hesham M
- Al-Raddadi Rajaa M
- Alahdab Fares
- Alam Khurshid
- Alam Tahiya
- Albujeer Ammar
- Alebel Animut
- Alene Kefyalew Addis
- Alhabib Samia
- Ali Raghib
- Alijanzadeh Mehran
- Alizadeh-Navaei Reza
- Aljunid Syed Mohamed
- Alkerwi Ala'a
- Alla François
- Allebeck Peter
- Allen Christine A
- Almasi Ali
- Alonso Jordi
- Alsharif Ubai
- Altirkawi Khalid
- Alvis-Guzman Nelson
- Amare Azmeraw T
- Amenu Kebede
- Amini Erfan
- Ammar Walid
- Anber Nahla Hamed
- Anderson Jason A
- Andrei Catalina Liliana
- Androudi Sofia
- Animut Megbaru Debalkie
- Anjomshoa Mina
- Ansari Hossein
- Ansariadi Ansariadi
- Ansha Mustafa Geleto
- Antonio Carl Abelardo T
- Anwari Palwasha
- Appiah Lambert Tetteh
- Aremu Olatunde
- Areri Habtamu Abera
- Arora Monika
- Aryal Krishna K
- Asayesh Hamid
- Asfaw Ephrem Tsegay
- Asgedom Solomon Weldegebreal
- Asghar Rana Jawad
- Assadi Reza
- Ataro Zerihun
- Atique Suleman
- Atre Sachin R
- Atteraya Madhu Sudhan
- Ausloos Marcel
- Avila-Burgos Leticia
- Avokpaho Euripide F G A
- Awasthi Ashish
- Ayala Quintanilla Beatriz Paulina
- Ayele Henok Tadesse
- Ayele Yohanes
- Ayer Rakesh
- Azarpazhooh Mahmoud Reza
- Azzopardi Peter S
- Azzopardi-Muscat Natasha
- Babalola Tesleem Kayode
- Babazadeh Arefeh
- Badali Hamid
- Badawi Alaa
- Balakrishnan Kalpana
- Bali Ayele Geleto
- Banach Maciej
- Banerjee Amitava
- Banoub Joseph Adel Mattar
- Banstola Amrit
- Barac Aleksandra
- Barboza Miguel A
- Barker-Collo Suzanne Lyn
- Barrero Lope H
- Barthelemy Celine M
- Bassat Quique
- Basu Arindam
- Basu Sanjay
- Battista Robert J
- Baune Bernhard T
- Baynes Habtamu Wondifraw
- Bazargan-Hejazi Shahrzad
- Bedi Neeraj
- Beghi Ettore
- Behzadifar Masoud
- Behzadifar Meysam
- Bekele Bayu Begashaw
- Belachew Abate Bekele
- Belay Aregawi Gebreyesus
- Belay Saba Abraham
- Belay Yihalem Abebe
- Bell Michelle L
- Bello Aminu K
- Bennett Derrick A
- Bensenor Isabela M
- Benzian Habib
- Berhane Adugnaw
- Berhe Abadi Kidanemariam
- Berman Adam E
- Bernabe Eduardo
- Bernstein Robert S
- Bertolacci Gregory J
- Beuran Mircea
- Beyranvand Tina
- Bhala Neeraj
- Bhalla Ashish
- Bhansali Anil
- Bhattarai Suraj
- Bhaumik Soumyadeep
- Bhutta Zulfiqar A
- Biadgo Belete
- Biehl Molly H
- Bijani Ali
- Bikbov Boris
- Bililign Nigus
- Bin Sayeed Muhammad Shahdaat
- Birlik Sait Mentes
- Birungi Charles
- Bisanzio Donal
- Biswas Tuhin
- Bitew Helen
- Bizuneh Hailemichael
- Bjertness Espen
- Bobasa Eshetu Mulisa
- Boufous Soufiane
- Bourne Rupert
- Bozorgmehr Kayvan
- Bragazzi Nicola Luigi
- Brainin Michael
- Brant Luisa C
- Brauer Michael
- Brazinova Alexandra
- Breitborde Nicholas J K
- Briant Paul Svitil
- Britton Gabrielle
- Brugha Traolach
- Bukhman Gene
- Busse Reinhard
- Butt Zahid A
- Bärnighausen Till Winfried
- Béjot Yannick
- Cahuana-Hurtado Lucero
- Callender Charlton SKH
- Campos-Nonato Ismael R
- Campuzano Rincon Julio Cesar
- Cano Jorge
- Car Josip
- Car Mate
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- Carter Austin
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- Castañeda-Orjuela Carlos A
- Castillo Rivas Jacqueline
- Castro Franz
- Causey Kate
- Cercy Kelly M
- Cerin Ester
- Chaiah Yazan
- Chalek Julian
- Chang Hsing-Yi
- Chang Jung-Chen
- Chattopadhyay Aparajita
- Chattu Vijay Kumar
- Chaturvedi Pankaj
- Chiang Peggy Pei-Chia
- Chin Ken Lee
- Chisumpa Vesper Hichilombwe
- Chitheer Abdulaal
- Choi Jee-Young J
- Chowdhury Rajiv
- Christensen Hanne
- Christopher Devasahayam J
- Chung Sheng-Chia
- Cicuttini Flavia M
- Ciobanu Liliana G
- Cirillo Massimo
- Claro Rafael M
- Claßen Thomas Khaled Dwayne
- Cohen Aaron J
- Collado-Mateo Daniel
- Cooper Cyrus
- Cooper Leslie Trumbull
- Cornaby Leslie
- Cortinovis Monica
- Costa Megan
- Cousin Ewerton
- Cromwell Elizabeth A
- Crowe Christopher Stephen
- Cunningham Matthew
- Cárdenas Rosario
- Daba Alemneh Kabeta
- Dadi Abel Fekadu
- Dandona Lalit
- Dandona Rakhi
- Dang Anh Kim
- Dargan Paul I
- Daryani Ahmad
- Das Gupta Rajat
- das Neves José
- Das Siddharth K
- Dasa Tamirat Tesfaye
- Dash Aditya Prasad
- Davis Adrian C
- Davitoiu Dragos Virgil
- Davletov Kairat
- Dayama Anand
- de Courten Barbora
- De Leo Diego
- De Neve Jan-Walter
- De Steur Hans
- Degefa Meaza Girma
- Degenhardt Louisa
- Degfie Tizta Tilahun
- Deiparine Selina
- Dellavalle Robert P
- Demoz Gebre Teklemariam
- Demtsu Balem
- Denova-Gutiérrez Edgar
- Deribe Kebede
- Dervenis Nikolaos
- Dessie Getenet Ayalew
- Dey Subhojit
- Dharmaratne Samath D
- Dhimal Meghnath
- Dicker Daniel
- Dinberu Mesfin Tadese
- Ding Eric L
- Djalalinia Shirin
- Do Huyen Phuc
- Dokova Klara
- Doku David Teye
- Douwes-Schultz Dirk
- Driscoll Tim Robert
- Duan Leilei
- Dubey Manisha
- Dubljanin Eleonora
- Duken Eyasu Ejeta
- Duncan Bruce B
- Duraes Andre R
- Ebrahimpour Soheil
- Edvardsson David
- El Bcheraoui Charbel
- El-Khatib Ziad
- Eldrenkamp Erika
- Elyazar Iqbal RF
- Enayati Ahmadali
- Endries Aman Yesuf
- Eshrati Babak
- Eskandarieh Sharareh
- Esteghamati Alireza
- Esteghamati Sadaf
- Estep Kara
- Fakhar Mahdi
- Fakhim Hamed
- Fanzo Jessica
- Faramarzi Mahbobeh
- Fareed Mohammad
- Farhadi Farzaneh
- Farid Talha A
- Farinha Carla Sofia e Sá
- Farioli Andrea
- Faro Andre
- Farvid Maryam S
- Farzadfar Farshad
- Farzaei Mohammad Hosein
- Farzam Hossein
- Fazaeli Ali Akbar
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- Feigl Andrea B
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- Feldman Rachel
- Fentahun Netsanet
- Fereshtehnejad Seyed-Mohammad
- Fernandes Eduarda
- Fernandes Joao C
- Feyissa Garumma Tolu
- Fijabi Daniel Obadare
- Filip Irina
- Finegold Samuel
- Finger Jonas David
- Fischer Florian
- Fitzmaurice Christina
- Flor Luisa Sorio
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- Foreman Kyle J
- Frank Tahvi D
- Franklin Richard Charles
- Fukumoto Takeshi
- Fukutaki Kai
- Fuller John E
- Fullman Nancy
- Furtado João M
- Fürst Thomas
- Gakidou Emmanuela
- Gallus Silvano
- Gankpe Fortune Gbetoho
- Gansevoort Ron T
- Garcia Ana Cristina
- Garcia-Basteiro Alberto L
- Garcia-Gordillo Miguel A
- Gardner William M
- Gebre Abadi Kahsu
- Gebre Teshome
- Gebregergs Gebremedhin Berhe
- Gebrehiwot Tsegaye Tewelde
- Gebremedhin Amanuel Tesfay
- Gebremichael Bereket
- Gebremichael Teklu Gebrehiwo
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- Tortajada-Girbés Miguel
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- Towbin Jeffrey A
- Tran Bach Xuan
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- Tripathy Srikanth Prasad
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- Truelsen Thomas Clement
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- Ullah Irfan
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- Werdecker Andrea
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- Whisnant Joanna L
- Whiteford Harvey A
- Widecka Justyna
- Widecka Katarzyna
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- Wilner Lauren B
- Winkler Andrea Sylvia
- Wiyeh Alison B
- Wiysonge Charles Shey
- Wolde Haileab Fekadu
- Wolfe Charles D A
- Wu Shouling
- Xavier Denis
- Xu Gelin
- Xu Rixing
- Yadollahpour Ali
- Yahyazadeh Jabbari Seyed Hossein
- Yakob Bereket
- Yamada Tomohide
- Yan Lijing L
- Yano Yuichiro
- Yaseri Mehdi
- Yasin Yasin Jemal
- Ye Pengpeng
- Yearwood Jamal A
- Yeshaneh Alex
- Yimer Ebrahim M
- Yip Paul
- Yirsaw Biruck Desalegn
- Yisma Engida
- Yonemoto Naohiro
- Yonga Gerald
- Yoon Seok-Jun
- Yotebieng Marcel
- Younis Mustafa Z
- Yousefifard Mahmoud
- Yu Chuanhua
- Zaman Sojib Bin
- Zamani Mohammad
- Zare Zohreh
- Zavala-Arciniega Luis
- Zegeye Desalegn Tegabu
- Zegeye Elias Asfaw
- Zeleke Ayalew Jejaw
- Zendehdel Kazem
- Zerfu Taddese Alemu
- Zhang Anthony Lin
- Zhang Xueying
- Zhou Maigeng
- Zhu Jun
- Zimsen Stephanie R M
- Zodpey Sanjay
- Zoeckler Leo
- Zucker Inbar
- Zuhlke Liesel Joanna J
- Ärnlöv Johan
- Çavlin Alanur
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2018
- Field of study
BACKGROUND: Efforts to establish the 2015 baseline and monitor early implementation of the UN Sustainable Development Goals (SDGs) highlight both great potential for and threats to improving health by 2030. To fully deliver on the SDG aim of 'leaving no one behind', it is increasingly important to examine the health-related SDGs beyond national-level estimates. As part of the Global Burden of Diseases, Injuries, and Risk Factors Study 2017 (GBD 2017), we measured progress on 41 of 52 health-related SDG indicators and estimated the health-related SDG index for 195 countries and territories for the period 1990-2017, projected indicators to 2030, and analysed global attainment. METHODS: We measured progress on 41 health-related SDG indicators from 1990 to 2017, an increase of four indicators since GBD 2016 (new indicators were health worker density, sexual violence by non-intimate partners, population census status, and prevalence of physical and sexual violence [reported separately]). We also improved the measurement of several previously reported indicators. We constructed national-level estimates and, for a subset of health-related SDGs, examined indicator-level differences by sex and Socio-demographic Index (SDI) quintile. We also did subnational assessments of performance for selected countries. To construct the health-related SDG index, we transformed the value for each indicator on a scale of 0-100, with 0 as the 2·5th percentile and 100 as the 97·5th percentile of 1000 draws calculated from 1990 to 2030, and took the geometric mean of the scaled indicators by target. To generate projections through 2030, we used a forecasting framework that drew estimates from the broader GBD study and used weighted averages of indicator-specific and country-specific annualised rates of change from 1990 to 2017 to inform future estimates. We assessed attainment of indicators with defined targets in two ways: first, using mean values projected for 2030, and then using the probability of attainment in 2030 calculated from 1000 draws. We also did a global attainment analysis of the feasibility of attaining SDG targets on the basis of past trends. Using 2015 global averages of indicators with defined SDG targets, we calculated the global annualised rates of change required from 2015 to 2030 to meet these targets, and then identified in what percentiles the required global annualised rates of change fell in the distribution of country-level rates of change from 1990 to 2015. We took the mean of these global percentile values across indicators and applied the past rate of change at this mean global percentile to all health-related SDG indicators, irrespective of target definition, to estimate the equivalent 2030 global average value and percentage change from 2015 to 2030 for each indicator
Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021
- Author
- Aali Amirali
- Abbafati Cristiana
- Abbas Jaffar
- Abbasgholizadeh Rouzbeh
- Abbasi Madineh Akram
- Abbasian Mohammadreza
- Abd ElHafeez Samar
- Abd-Elsalam Sherief
- Abdelmasseh Michael
- Abdelwahab Ahmed
- Abdollahi Mohammad
- Abdoun Meriem
- Abdullahi Auwal
- Abdurehman Ame Mehadi
- Abebe Mesfin
- Abedi Aidin
- Abedi Armita
- Abegaz Tadesse M
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- Langguth Berthold
- Lansingh Van Charles
- Laplante-Lévesque Ariane
- Larijani Bagher
- Larsson Anders O
- Lasrado Savita
- Latief Kamaluddin
- Latif Mahrukh
- Latifinaibin Kaveh
- Lauriola Paolo
- Lám Judit
- Le Long Khanh Dao
- Le Nhi Huu Hanh
- Le Thao Thi Thu
- Le Trang Diep Thanh
- Lee Munjae
- Lee Paul H
- Lee Sang-woong
- Lee Seung Won
- Lee Wei-Chen
- Lee Yo Han
- Legesse Samson Mideksa
- Leigh James
- Lenzi Jacopo
- Leong Elvynna
- Lerango Temesgen L
- Li Ming-Chieh
- Li Wei
- Li Xiaopan
- Li Yichong
- Li Zhihui
- Libra Massimo
- Ligade Virendra S
- Likaka Andrew Tiyamike Makhiringa
- Lim Lee-Ling
- Lim Stephen S
- Lin Ro-Ting
- Lin Shuzhi
- Lioutas Vasileios-Arsenios
- Listl Stefan
- Liu Jue
- Liu Simin
- Liu Xiaofeng
- Livingstone Katherine M
- Llanaj Erand
- Lo Chun-Han
- Loreche Arianna Maever
- Lorenzovici László
- Lotfi Mojgan
- Lotfizadeh Masoud
- Lozano Rafael
- Lubinda Jailos
- Lucchetti Giancarlo
- Lugo Alessandra
- Lunevicius Raimundas
- Ma Jianing
- Ma Stefan
- Ma Zheng Feei
- Mabrok Mahmoud
- Machairas Nikolaos
- Machoy Monika
- Madsen Christian
- Magaña Gómez Javier A
- Maghazachi Azzam A
- Maharaj Sandeep B
- Maharjan Preeti
- Mahjoub Soleiman
- Mahmoud Mansour Adam
- Mahmoudi Elham
- Mahmoudi Morteza
- Makram Omar Mohamed
- Malagón-Rojas Jeadran N
- Malakan Rad Elaheh
- Malekzadeh Reza
- Malhotra Armaan K
- Malhotra Kashish
- Malik Ahmad Azam
- Malik Iram
- Malinga Lesibana Anthony
- Malta Deborah Carvalho
- Mamun Abdullah A
- Manla Yosef
- Mannan Fahmida
- Mansoori Yasaman
- Mansour Ali
- Mansouri Vahid
- Mansournia Mohammad Ali
- Mantovani Lorenzo Giovanni
- Marasini Bishnu P
- Marateb Hamid Reza
- Maravilla Joemer C
- Marconi Agustina M
- Mardi Parham
- Marino Mirko
- Marjani Abdoljalal
- Marrugo Arnedo Carlos Alberto
- Martinez-Guerra Bernardo Alfonso
- Martinez-Piedra Ramon
- Martins Cleodice A
- Martins-Melo Francisco Rogerlândio
- Martorell Miquel
- Marx Wolfgang
- Maryam Sharmeen
- Marzo Roy Rillera
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- Matei Clara N
- Mathioudakis Alexander G
- Maude Richard James
- Maugeri Andrea
- May Erin A
- Mayeli Mahsa
- Mazaheri Maryam
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- Mediratta Rishi P
- Meena Jitendra Kumar
- Mehari Medhin
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- Mehra Rahul
- Mehrabani-Zeinabad Kamran
- Mehrabi Nasab Entezar
- Mehrotra Ravi
- Mekonnen Mathewos M
- Mendoza Walter
- Menezes Ritesh G
- Mengesha Endalkachew Worku
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- Mentis Alexios-Fotios A
- Meo Sultan Ayoub
- Meretoja Atte
- Meretoja Tuomo J
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- Mesfin Bezawit Afework
- Mestrovic Tomislav
- Mhlanga Adquate
- Mhlanga Laurette
- Mi Tianyue
- Micha Georgia
- Michalek Irmina Maria
- Miller Ted R
- Mindlin Sergey Nikolaevich
- Minelli Giada
- Minh Le Huu Nhat
- Mini GK
- Minja Neema W
- Mirdamadi Niloofar
- Mirghafourvand Mojgan
- Mirica Andreea
- Mirinezhad Seyed Kazem
- Mirmosayyeb Omid
- Mirutse Mizan Kiros
- Mirza-Aghazadeh-Attari Mohammad
- Mirzaei Maryam
- Misgana Tadesse
- Misra Sanjeev
- Mitchell Philip B
- Mithra Prasanna
- Mittal Chaitanya
- Mittal Madhukar
- Moazen Babak
- Mohamed Ahmed Ismail
- Mohamed Jama
- Mohamed Mouhand F H
- Mohamed Nouh Saad
- Mohammad-Alizadeh-Charandabi Sakineh
- Mohammad-pour Saeed
- Mohammadi Soheil
- Mohammadian-Hafshejani Abdollah
- Mohammadshahi Marita
- Mohammed Mustapha
- Mohammed Salahuddin
- Mohammed Shafiu
- Mojiri-forushani Hoda
- Mokdad Ali H
- Mokhtarzadehazar Peyman
- Momenzadeh Kaveh
- Momtazmanesh Sara
- Monasta Lorenzo
- Moni Mohammad Ali
- Montazeri Fateme
- Moodi Ghalibaf AmirAli
- Moradi Maryam
- Moradi Yousef
- Moradi-Lakeh Maziar
- Moradinazar Mehdi
- Moradpour Farhad
- Moraga Paula
- Morawska Lidia
- Moreira Rafael Silveira
- Morovatdar Negar
- Morrison Shane Douglas
- Morze Jakub
- Mosaddeghi Heris Reza
- Mosser Jonathan F
- Mossialos Elias
- Mostafavi Hakimeh
- Mostofinejad Amirmahdi
- Mougin Vincent
- Mouodi Simin
- Mousavi Khaneghah Amin
- Mousavi Parsa
- Mousavi Seyed Ehsan
- Mpundu-Kaambwa Christine
- Mrejen Matías
- Mubarik Sumaira
- Muccioli Lorenzo
- Mueller Ulrich Otto
- Mughal Faraz
- Mukherjee Sumoni
- Mukoro George Duke
- Mulita Admir
- Mulita Francesk
- Muniyandi Malaisamy
- Munjal Kavita
- Murray Christopher J L
- Musaigwa Fungai
- Musallam Khaled M
- Mustafa Ghulam
- Muthu Sathish
- Muthupandian Saravanan
- Myung Woojae
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- Nafukho Fredrick Muyia
- Nagarajan Ahamarshan Jayaraman
- Naghavi Mohsen
- Naghavi Pirouz
- Naik Ganesh R
- Naik Gurudatta
- Naimzada Mukhammad David
- Nair Sanjeev
- Nair Tapas Sadasivan
- Najmuldeen Hastyar Hama Rashid
- Naldi Luigi
- Nangia Vinay
- Nargus Shumaila
- Nascimento Bruno Ramos
- Nascimento Gustavo G
- Naser Abdallah Y
- Nasiri Mohammad Javad
- Natto Zuhair S
- Nauman Javaid
- Naveed Muhammad
- Nayak Biswa Prakash
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- Nayyar Ashish Kumar
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- Negash Hadush
- Negero Amayu Kumesa
- Negoi Ionut
- Negoi Ruxandra Irina
- Negru Serban Mircea
- Nejadghaderi Seyed Aria
- Nejjari Chakib
- Nematollahi Mohammad Hadi
- Nena Evangelia
- Nepal Samata
- Nesbit Olivia D
- Newton Charles Richard James
- Ngunjiri Josephine W
- Nguyen Dang H
- Nguyen Phat Tuan
- Nguyen Phuong The
- Nguyen Tuan Thanh
- Nguyen Van Thanh
- Nigatu Yeshambel T
- Nikolouzakis Taxiarchis Konstantinos
- Nikoobar Ali
- Nikpoor Amin Reza
- Nizam Muhammad A
- Nomura Shuhei
- Noreen Mamoona
- Noroozi Nafise
- Norouzian Baghani Abbas
- Norrving Bo
- Noubiap Jean Jacques
- Novotney Amanda
- Nri-Ezedi Chisom Adaobi
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- Ntsekhe Mpiko
- Nuñez-Samudio Virginia
- Nurrika Dieta
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- Okonji Osaretin Christabel
- Okwute Patrick Godwin
- Olagunju Andrew T
- Olaiya Muideen Tunbosun
- Olanipekun Titilope O
- Olatubi Matthew Idowu
- Olivas-Martinez Antonio
- Oliveira Gláucia Maria Moraes
- Oliver Susan
- Olorukooba Abdulhakeem Abayomi
- Olufadewa Isaac Iyinoluwa
- Olusanya Bolajoko Olubukunola
- Olusanya Jacob Olusegun
- Oluwafemi Yinka Doris
- Oluwatunase Gideon Olamilekan
- Omar Hany A
- Omer Goran Latif
- Ong Sokking
- Onwujekwe Obinna E
- Onyedibe Kenneth Ikenna
- Opio John Nelson
- Ordak Michal
- Orellana E Roberto
- Orisakwe Orish Ebere
- Orish Verner N
- Orru Hans
- Ortega-Altamirano Doris V
- Ortiz Alberto
- Ortiz-Brizuela Edgar
- Ortiz-Prado Esteban
- Osuagwu Uchechukwu Levi
- Otoiu Adrian
- Otstavnov Nikita
- Ouyahia Amel
- Ouyang Guoqing
- Owolabi Mayowa O
- Oyeyemi Ifeoluwa Temitayo
- Oyeyemi Oyetunde T
- Ozten Yaz
- P A Mahesh Padukudru
- Padubidri Jagadish Rao
- Pahlavikhah Varnosfaderani Mahsa
- Pal Pramod Kumar
- Palicz Tamás
- Palladino Claudia
- Palladino Raffaele
- Palma-Alvarez Raul Felipe
- Pana Adrian
- Panahi Parsa
- Pandey Ashok
- Pandi-Perumal Seithikurippu R
- Pando-Robles Victoria
- Pangaribuan Helena Ullyartha
- Panos Georgios D
- Pantazopoulos Ioannis
- Papadopoulou Paraskevi
- Pardhan Shahina
- Parikh Romil R
- Park Seoyeon
- Parthasarathi Ashwaghosha
- Pashaei Ava
- Pasupula Deepak Kumar
- Patel Jenil R
- Patel Sangram Kishor
- Pathan Aslam Ramjan
- Patil Ashlesh
- Patil Shankargouda
- Patoulias Dimitrios
- Patthipati Venkata Suresh
- Paudel Uttam
- Pawar Shrikant
- Pazoki Toroudi Hamidreza
- Pease Spencer A
- Peden Amy E
- Pedersini Paolo
- Peng Minjin
- Pensato Umberto
- Pepito Veincent Christian Filipino
- Peprah Emmanuel K
- Pereira Gavin
- Pereira Jeevan
- Pereira Marcos
- Peres Mario F P
- Perianayagam Arokiasamy
- Perico Norberto
- Petcu Ionela-Roxana
- Petermann-Rocha Fanny Emily
- Pezzani Raffaele
- Pham Hoang Tran
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- Pierannunzio Daniela
- Pigeolet Manon
- Pigott David M
- Pilgrim Thomas
- Pinheiro Marina
- Piradov Michael A
- Plakkal Nishad
- Plotnikov Evgenii
- Poddighe Dimitri
- Pollner Peter
- Poluru Ramesh
- Pond Constance Dimity
- Postma Maarten J
- Poudel Govinda Raj
- Poudel Lisasha
- Pourali Ghazaleh
- Pourtaheri Naeimeh
- Prada Sergio I
- Pradhan Pranil Man Singh
- Prajapati Vijay Kumar
- Prakash V
- Prasad Chandra P
- Prasad Manya
- Prashant Akila
- Prates Elton Junio Sady
- Purnobasuki Hery
- Purohit Bharathi M
- Puvvula Jagadeesh
- Qaisar Rizwan
- Qasim Nameer Hashim
- Qattea Ibrahim
- Qian Gangzhen
- Quan Nguyen Khoi
- Radfar Amir
- Radhakrishnan Venkatraman
- Raee Pourya
- Raeisi Shahraki Hadi
- Rafiei Alavi Seyedeh Niloufar
- Rafique Ibrar
- Raggi Alberto
- Rahim Fakher
- Rahman Md Mosfequr
- Rahman Mosiur
- Rahman Muhammad Aziz
- Rahman Tafhimur
- Rahmani Amir Masoud
- Rahmani Shayan
- Rahnavard Niloufar
- Rai Pramila
- Rajaa Sathish
- Rajabpour-Sanati Ali
- Rajput Prashant
- Ram Prasanna
- Ramadan Hazem
- Ramasamy Shakthi Kumaran
- Ramazanu Sheena
- Rana Juwel
- Rana Kritika
- Ranabhat Chhabi Lal
- Rancic Nemanja
- Rani Smitha
- Ranjan Shubham
- Rao Chythra R
- Rao Indu Ramachandra
- Rao Mithun
- Rao Sowmya J
- Rasali Drona Prakash
- Rasella Davide
- Rashedi Sina
- Rashedi Vahid
- Rashid Ahmed Mustafa
- Rasouli-Saravani Ashkan
- Rastogi Prateek
- Rasul Azad
- Ravangard Ramin
- Ravikumar Nakul
- Rawaf David Laith
- Rawaf Salman
- Rawassizadeh Reza
- Razeghian-Jahromi Iman
- Reddy Murali Mohan Rama Krishna
- Redwan Elrashdy Moustafa Mohamed
- Rehman Faizan Ur
- Reiner Jr Robert C
- Remuzzi Giuseppe
- Reshmi Bhageerathy
- Resnikoff Serge
- Reyes Luis Felipe
- Rezaee Malihe
- Rezaei Negar
- Rezaei Nima
- Rezaeian Mohsen
- Riaz Mavra A
- Ribeiro Ana Isabel
- Ribeiro Daniel Cury
- Rickard Jennifer
- Rios-Blancas Maria Jesus
- Robinson-Oden Hannah Elizabeth
- Rodrigues Mónica
- Rodriguez Jefferson Antonio Buendia
- Roever Leonardo
- Rohilla Ravi
- Rohloff Peter
- Romadlon Debby Syahru
- Ronfani Luca
- Roshandel Gholamreza
- Roshanzamir Sharareh
- Rostamian Morteza
- Roy Bedanta
- Roy Priyanka
- Rubagotti Enrico
- Rumisha Susan Fred
- Rwegerera Godfrey M
- Rynkiewicz Andrzej
- S N Chandan
- S Sunnerhagen Katharina
- S Manjula
- Saad Aly M A
- Sabbatucci Michela
- Saber Korosh
- Saber-Ayad Maha Mohamed
- Sacco Simona
- Saddik Basema
- Saddler Adam
- Sadee Bashdar Abuzed
- Sadeghi Ehsan
- Sadeghi Masoumeh
- Sadeghian Saeid
- Saeed Umar
- Saeedi Maryam
- Safi Sare
- Sagar Rajesh
- Saghazadeh Amene
- Saheb Sharif-Askari Narjes
- Sahoo Soumya Swaroop
- Sahraian Mohammad Ali
- Sajedi Seyed Aidin
- Sajid Mirza Rizwan
- Sakshaug Joseph W
- Salahi Saina
- Salahi Sarvenaz
- Salamati Payman
- Salami Afeez Abolarinwa
- Salaroli Luciane B
- Saleh Mohamed A
- Salehi Sana
- Salem Marwa Rashad
- Salem Mohammed Z Y
- Salimi Sohrab
- Samadi Kafil Hossein
- Samadzadeh Sara
- Samara Kamel A
- Samargandy Saad
- Samodra Yoseph Leonardo
- Samuel Vijaya Paul
- Samy Abdallah M
- Sanabria Juan
- Sanadgol Nima
- Sanganyado Edmond
- Sanjeev Rama Krishna
- Sanmarchi Francesco
- Sanna Francesca
- Santri Ichtiarini Nurullita
- Santric-Milicevic Milena M
- Sarasmita Made Ary
- Saravanan Aswini
- Saravi Babak
- Sarikhani Yaser
- Sarkar Chinmoy
- Sarmiento-Suárez Rodrigo
- Sarode Gargi Sachin
- Sarode Sachin C
- Sarveazad Arash
- Sathian Brijesh
- Sathish Thirunavukkarasu
- Sattin Davide
- Saulam Jennifer
- Sawyer Susan M
- Saxena Sonia
- Saya Ganesh Kumar
- Sayadi Yaser
- Sayeed Abu
- Sayeed Md Abu
- Saylan Mete
- Scarmeas Nikolaos
- Schaarschmidt Benedikt Michael
- Schlee Winfried
- Schmidt Maria Inês
- Schuermans Art
- Schumacher Austin E
- Schwebel David C
- Schwendicke Falk
- Selvaraj Siddharthan
- Semreen Mohammad H
- Senapati Sabyasachi
- Sengupta Pallav
- Senthilkumaran Subramanian
- Sepanlou Sadaf G
- Serban Dragos
- Sertsu Addisu
- Sethi Yashendra
- SeyedAlinaghi SeyedAhmad
- Seyedi Seyed Arsalan
- Shafaat Amir
- Shafaat Omid
- Shafie Mahan
- Shafiee Arman
- Shah Nilay S
- Shah Pritik A
- Shahabi Saeed
- Shahbandi Ataollah
- Shahid Izza
- Shahid Samiah
- Shahid Wajeehah
- Shahwan Moyad Jamal
- Shaikh Masood Ali
- Shakeri Alireza
- Shakil Husain
- Sham Sunder
- Shamim Muhammad Aaqib
- Shams-Beyranvand Mehran
- Shamshad Hina
- Shamshirgaran Mohammad Ali
- Shamsi Mohammad Anas
- Shanawaz Mohd
- Shankar Abhishek
- Sharfaei Sadaf
- Sharifan Amin
- Shariff Mariam
- Sharifi-Rad Javad
- Sharma Manoj
- Sharma Rajesh
- Sharma Saurab
- Sharma Vishal
- Shastry Rajesh P
- Shavandi Amin
- Shaw David H
- Shayan Amir Mehdi
- Shehabeldine Amr Mohamed Elsayed
- Sheikh Aziz
- Sheikhi Rahim Ali
- Shen Jiabin
- Shenoy Manjunath Mala
- Shetty B Suresh Kumar
- Shetty Ranjitha S
- Shey Robert Adamu
- Shiani Amir
- Shibuya Kenji
- Shiferaw Desalegn
- Shigematsu Mika
- Shin Jae Il
- Shin Min-Jeong
- Shiri Rahman
- Shirkoohi Reza
- Shittu Aminu
- Shiue Ivy
- Shivakumar K M
- Shivarov Velizar
- Shool Sina
- Shrestha Sunil
- Shuja Kanwar Hamza
- Shuval Kerem
- Si Yafei
- Sibhat Migbar Mekonnen
- Siddig Emmanuel Edwar
- Sigfusdottir Inga Dora
- Silva João Pedro
- Silva Luís Manuel Lopes Rodrigues
- Silva Soraia
- Simões Jorge Piano
- Simpson Colin R
- Singal Anjali
- Singh Abhinav
- Singh Aditya
- Singh Ambrish
- Singh Balbir Bagicha
- Singh Baljinder
- Singh Mahendra
- Singh Mayank
- Singh Narinder Pal
- Singh Paramdeep
- Singh Surjit
- Siraj Md Shahjahan
- Sitas Freddy
- Sivakumar Shravan
- Skryabin Valentin Yurievich
- Skryabina Anna Aleksandrovna
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- Slepak Erica Leigh N
- Sohrabi Hanye
- Soleimani Hamidreza
- Soliman Sameh S M
- Solmi Marco
- Solomon Yonatan
- Song Yimeng
- Sorensen Reed J D
- Soriano Joan B
- Soyiri Ireneous N
- Spartalis Michael
- Sreeramareddy Chandrashekhar T
- Starnes Joseph R
- Starodubov Vladimir I
- Starodubova Antonina V
- Stefan Simona Cătălina
- Stein Dan J
- Steinbeis Fridolin
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- Stokes Mark A
- Stortecky Stefan
- Stranges Saverio
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- Suliankatchi Abdulkader Rizwan
- Sultana Abida
- Sun Jing
- Sunkersing David
- Susanty Sri
- Swain Chandan Kumar
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- Szarpak Lukasz
- Szeto Mindy D
- Szócska Miklós
- Šekerija Mario
- Tabaee Damavandi Payam
- Tabatabaei Malazy Ozra
- Tabatabaeizadeh Seyed-Amir
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- Tabb Karen M
- Tabish Mohammad
- Taborda-Barata Luis M
- Tabuchi Takahiro
- Tadesse Birkneh Tilahun
- Taheri Abkenar Yasaman
- Taheri Soodejani Moslem
- Taheri Amirmasoud
- Taherkhani Amir
- Taiba Jabeen
- Tajbakhsh Ardeshir
- Talaat Iman M
- Talukder Ashis
- Tamuzi Jacques Lukenze
- Tan Ker-Kan
- Tang Haosu
- Tang Hong K
- Tat Nathan Y
- Tat Vivian Y
- Tavakoli Oliaee Razieh
- Tavangar Seyed Mohammad
- Taveira Nuno
- Tebeje Tsion Mulat
- Tefera Yibekal Manaye
- Teimoori Mojtaba
- Temsah Mohamad-Hani
- Temsah Reem Mohamad Hani
- Teramoto Masayuki
- Tesfaye Solomon Hailemariam
- Thangaraju Pugazhenthan
- Thankappan Kavumpurathu Raman
- Thapa Rajshree
- Thapar Rekha
- Thomas Nihal
- Thrift Amanda G
- Thum Chern Choong Chern
- Tian Jing
- Tichopad Ales
- Ticoalu Jansje Henny Vera
- Tiruye Tenaw Yimer
- Tohidast Seyed Abolfazl
- Tonelli Marcello
- Touvier Mathilde
- Tovani-Palone Marcos Roberto
- Tram Khai Hoan
- Tran Nghia Minh
- Trico Domenico
- Trihandini Indang
- Tromans Samuel Joseph
- Truong Vien T
- Truyen Thien Tan Tri Tai
- Tsermpini Evangelia Eirini
- Tumurkhuu Munkhtuya
- Tung Kang
- Tyrovolas Stefanos
- Ubah Chukwudi S
- Udoakang Aniefiok John
- Udoh Arit
- Ulhaq Inam
- Ullah Saeed
- Ullah Sana
- Umair Muhammad
- Umar Tungki Pratama
- Umeokonkwo Chukwuma David
- Umesh Anushri
- Unim Brigid
- Unnikrishnan Bhaskaran
- Upadhyay Era
- Urso Daniele
- Vacante Marco
- Vahdani Amir Mohammad
- Vaithinathan Asokan Govindaraj
- Valadan Tahbaz Sahel
- Valizadeh Rohollah
- Van den Eynde Jef
- Varavikova Elena
- Varga Orsolya
- Varma Siddhartha Alluri
- Vart Priya
- Varthya Shoban Babu
- Vasankari Tommi Juhani
- Veerman Lennert J
- Venketasubramanian Narayanaswamy
- Venugopal Deneshkumar
- Verghese Nicholas Alexander
- Verma Madhur
- Verma Pratibha
- Veroux Massimiliano
- Verras Georgios-Ioannis
- Vervoort Dominique
- Vieira Rafael José
- Villafañe Jorge Hugo
- Villani Leonardo
- Villanueva Gabriela Ines
- Villeneuve Paul J
- Violante Francesco S
- Visontay Rachel
- Vlassov Vasily
- Vo Bay
- Vollset Stein Emil
- Volovat Simona Ruxandra
- Volovici Victor
- Vongpradith Avina
- Vos Theo
- Vujcic Isidora S
- Vukovic Rade
- Wado Yohannes Dibaba
- Wafa Hatem A
- Waheed Yasir
- Wamai Richard G
- Wang Cong
- Wang Denny
- Wang Fang
- Wang Shu
- Wang Song
- Wang Yanzhong
- Wang Yuan-Pang
- Ward Paul
- Watson Stefanie
- Weaver Marcia R
- Weerakoon Kosala Gayan
- Weiss Daniel J
- Weldemariam Abrha Hailay
- Wells Katherine M
- Wen Yi Feng
- Werdecker Andrea
- Westerman Ronny
- Wickramasinghe Dakshitha Praneeth
- Wickramasinghe Nuwan Darshana
- Wijeratne Tissa
- Wilson Shadrach
- Wojewodzic Marcin W
- Wool Eve E
- Woolf Anthony D
- Wu Dongze
- Wulandari Ratna Dwi
- Xiao Hong
- Xu Bin
- Xu Xiaoyue
- Yadav Lalit
- Yaghoubi Sajad
- Yang Lin
- Yano Yuichiro
- Yao Yao
- Ye Pengpeng
- Yesera Gesila Endashaw
- Yesodharan Renjulal
- Yesuf Subah Abderehim
- Yiğit Arzu
- Yiğit Vahit
- Yip Paul
- Yon Dong Keon
- Yonemoto Naohiro
- You Yuyi
- Younis Mustafa Z
- Yu Chuanhua
- Zadey Siddhesh
- Zadnik Vesna
- Zafari Nima
- Zahedi Mohammad
- Zahid Muhammad Nauman
- Zahir Mazyar
- Zakham Fathiah
- Zaki Nazar
- Zakzuk Josefina
- Zamagni Giulia
- Zaman Burhan Abdullah
- Zaman Sojib Bin
- Zamora Nelson
- Zand Ramin
- Zandi Milad
- Zandieh Ghazal G Z
- Zanghì Aurora
- Zare Iman
- Zastrozhin Mikhail Sergeevich
- Zeariya Mohammed G M
- Zeng Youjie
- Zhai Chunxia
- Zhang Chen
- Zhang Haijun
- Zhang Hongwei
- Zhang Yunquan
- Zhang Zhaofeng
- Zhang Zhenyu
- Zhao Hanqing
- Zhao Yang
- Zhao Yong
- Zheng Peng
- Zhong Chenwen
- Zhou Juexiao
- Zhu Bin
- Zhu Zhaohua
- Ziaeefar Pardis
- Zielińska Magdalena
- Zou Zhiyong
- Zumla Alimuddin
- Zweck Elric
- Zyoud Samer H
- Publication venue
- Publication date
- 01/01/2024
- Field of study
Background: Estimates of demographic metrics are crucial to assess levels and trends of population health outcomes. The profound impact of the COVID-19 pandemic on populations worldwide has underscored the need for timely estimates to understand this unprecedented event within the context of long-term population health trends. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 provides new demographic estimates for 204 countries and territories and 811 additional subnational locations from 1950 to 2021, with a particular emphasis on changes in mortality and life expectancy that occurred during the 2020–21 COVID-19 pandemic period. Methods: 22 223 data sources from vital registration, sample registration, surveys, censuses, and other sources were used to estimate mortality, with a subset of these sources used exclusively to estimate excess mortality due to the COVID-19 pandemic. 2026 data sources were used for population estimation. Additional sources were used to estimate migration; the effects of the HIV epidemic; and demographic discontinuities due to conflicts, famines, natural disasters, and pandemics, which are used as inputs for estimating mortality and population. Spatiotemporal Gaussian process regression (ST-GPR) was used to generate under-5 mortality rates, which synthesised 30 763 location-years of vital registration and sample registration data, 1365 surveys and censuses, and 80 other sources. ST-GPR was also used to estimate adult mortality (between ages 15 and 59 years) based on information from 31 642 location-years of vital registration and sample registration data, 355 surveys and censuses, and 24 other sources. Estimates of child and adult mortality rates were then used to generate life tables with a relational model life table system. For countries with large HIV epidemics, life tables were adjusted using independent estimates of HIV-specific mortality generated via an epidemiological analysis of HIV prevalence surveys, antenatal clinic serosurveillance, and other data sources. Excess mortality due to the COVID-19 pandemic in 2020 and 2021 was determined by subtracting observed all-cause mortality (adjusted for late registration and mortality anomalies) from the mortality expected in the absence of the pandemic. Expected mortality was calculated based on historical trends using an ensemble of models. In location-years where all-cause mortality data were unavailable, we estimated excess mortality rates using a regression model with covariates pertaining to the pandemic. Population size was computed using a Bayesian hierarchical cohort component model. Life expectancy was calculated using age-specific mortality rates and standard demographic methods. Uncertainty intervals (UIs) were calculated for every metric using the 25th and 975th ordered values from a 1000-draw posterior distribution. Findings: Global all-cause mortality followed two distinct patterns over the study period: age-standardised mortality rates declined between 1950 and 2019 (a 62·8% [95% UI 60·5–65·1] decline), and increased during the COVID-19 pandemic period (2020–21; 5·1% [0·9–9·6] increase). In contrast with the overall reverse in mortality trends during the pandemic period, child mortality continued to decline, with 4·66 million (3·98–5·50) global deaths in children younger than 5 years in 2021 compared with 5·21 million (4·50–6·01) in 2019. An estimated 131 million (126–137) people died globally from all causes in 2020 and 2021 combined, of which 15·9 million (14·7–17·2) were due to the COVID-19 pandemic (measured by excess mortality, which includes deaths directly due to SARS-CoV-2 infection and those indirectly due to other social, economic, or behavioural changes associated with the pandemic). Excess mortality rates exceeded 150 deaths per 100 000 population during at least one year of the pandemic in 80 countries and territories, whereas 20 nations had a negative excess mortality rate in 2020 or 2021, indicating that all-cause mortality in these countries was lower during the pandemic than expected based on historical trends. Between 1950 and 2021, global life expectancy at birth increased by 22·7 years (20·8–24·8), from 49·0 years (46·7–51·3) to 71·7 years (70·9–72·5). Global life expectancy at birth declined by 1·6 years (1·0–2·2) between 2019 and 2021, reversing historical trends. An increase in life expectancy was only observed in 32 (15·7%) of 204 countries and territories between 2019 and 2021. The global population reached 7·89 billion (7·67–8·13) people in 2021, by which time 56 of 204 countries and territories had peaked and subsequently populations have declined. The largest proportion of population growth between 2020 and 2021 was in sub-Saharan Africa (39·5% [28·4–52·7]) and south Asia (26·3% [9·0–44·7]). From 2000 to 2021, the ratio of the population aged 65 years and older to the population aged younger than 15 years increased in 188 (92·2%) of 204 nations. Interpretation: Global adult mortality rates markedly increased during the COVID-19 pandemic in 2020 and 2021, reversing past decreasing trends, while child mortality rates continued to decline, albeit more slowly than in earlier years. Although COVID-19 had a substantial impact on many demographic indicators during the first 2 years of the pandemic, overall global health progress over the 72 years evaluated has been profound, with considerable improvements in mortality and life expectancy. Additionally, we observed a deceleration of global population growth since 2017, despite steady or increasing growth in lower-income countries, combined with a continued global shift of population age structures towards older ages. These demographic changes will likely present future challenges to health systems, economies, and societies. The comprehensive demographic estimates reported here will enable researchers, policy makers, health practitioners, and other key stakeholders to better understand and address the profound changes that have occurred in the global health landscape following the first 2 years of the COVID-19 pandemic, and longer-term trends beyond the pandemic
Global, regional, and national age-sex-specific mortality and life expectancy, 1950–2017: a systematic analysis for the Global Burden of Disease Study 2017
- Author
- A Mahesh P
- Abate Degu
- Abay Solomon M
- Abbafati Cristiana
- Abbasi Nooshin
- Abbastabar Hedayat
- Abd-Allah Foad
- Abdel-Rahman Omar
- Abdela Jemal
- Abdelalim Ahmed
- Abdi Alireza
- Abdollahpour Ibrahim
- Abdulkader Rizwan Suliankatchi
- Abebe Nebiyu Dereje
- Abebe Zegeye
- Abejie Ayenew Negesse
- Abera Semaw F.
- Abil Olifan Zewdie
- Aboyans Victor
- Abraha Haftom Niguse
- Abrham Aklilu Roba
- Abu-Raddad Laith Jamal
- Abu-Rmeileh Niveen M.
- Abyu Gebre Yitayih
- Accrombessi Manfred
- Acharya Dilaram
- Acharya Pawan
- Adamu Abdu A.
- Adebayo Oladimeji
- Adedeji I A
- Adedoyin Rufus Adesoji
- Adekanmbi Victor
- Adetokunboh Olatunji O.
- Adhena Beyene Meressa
- Adhikari Tara Ballav
- Adib Mina G.
- Adou Arsène Kouablan
- Adsuar Jose C.
- Afarideh Mohsen
- Afshari
- Afshin Ashkan
- Agarwal Gina
- Aghayan Sargis A.
- Agius Dominic
- Agrawal Anurag
- Agrawal Pankaj
- Agrawal Sutapa
- Ahmadi Alireza
- Ahmadi Mehdi
- Ahmadieh Hamid
- Ahmed Muktar Beshir
- Ahmed Sayem
- Akalu Temesgen Yihunie
- Akanda Ali Shafqat
- Akbari Mohammad Esmaeil
- Akibu Mohammed
- Akinyemi Rufus Olusola
- Akinyemiju Tomi
- Akseer Nadia
- Al Mamun Abdullah
- Al-Aly Ziyad
- Al-Eyadhy Ayman
- Al-Maskari Fatma
- Al-Mekhlafi Hesham M.
- Al-Raddadi R
- Alahdab Fares
- Alam Khurshid
- Alam Tahiya
- Albujeer Ammar
- Alebel Animut
- Alene Kefyalew Addis
- Alhabib Samia
- Ali Raghib
- Alijanzadeh Mehran
- Alizadeh-Navaei Reza
- Aljunid Syed Mohamed
- Alkerwi Ala'a
- Alla François
- Allebeck Peter
- Allen Christine A.
- Almasi Ali
- Alonso Jordi
- Alsharif Ubai
- Altirkawi Khalid A
- Alvis-Guzman Nelson
- Amare Azmeraw T.
- Amenu Kebede
- Amini Erfan
- Ammar Walid
- Anber Nahla
- Anderson Jason A.
- Andrei Catalina Liliana
- Androudi Sofia
- Animut Megbaru Debalkie
- Anjomshoa Mina
- Ansari Hossein
- Ansariadi Ansariadi
- Ansha Mustafa Geleto
- Antonio Carl Abelardo T.
- Anwari Palwasha
- Appiah Lambert Tetteh
- Aremu Olatunde
- Areri Habtamu Abera
- Arora Monika
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- Asayesh Hamid
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- Asgedom Solomon Weldegebreal
- Asghar Rana Jawad
- Assadi Reza
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- Atre Sachin R
- Atteraya Madhu Sudhan
- Ausloos Marcel
- Avila-Burgos Leticia
- Avokpaho Euripide Frinel G Arthur
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- Ayer Rakesh
- Azarpazhooh Mahmoud Reza
- Azzopardi Peter
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- Babalola Tesleem Kayode
- Babazadeh Arefeh
- Badali Hamid
- Badawi Alaa
- Balakrishnan Kalpana
- Bali Ayele Geleto
- Banach Maciej
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- De Leo Diego
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- Defo Barthelemy Kuate
- Degefa Meaza Girma
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- Deiparine Selina
- Dellavalle Robert P.
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- Nagarajan Ahamarshan Jayaraman
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- Neves José
- Newton Charles R.
- Ngalesoni Frida Namnyak
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- Nguyen Anh Quynh
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- Nguyen Ha
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- Nguyen Minh
- Nichols Emma
- Nigatu Solomon Gedlu
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- Nixon Molly R
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- Nouri Hamid Reza
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- Nyasulu Peter
- Obermeyer Carla Makhlouf
- Ofori-Asenso Richard
- Ogah Okechukwu S
- Ogbo Felix Akpojene
- Oh In-Hwan
- Okoro Anselm
- Oladimeji Kelechi Elizabeth
- Oladimeji Olanrewaju
- Olagunju Andrew T
- Olagunju Tinuke O
- Olivares Pedro R.
- Olsen Helen E
- Olusanya Bolajoko O.
- Olusanya Jacob Olusegun
- Ong Kanyin L.
- Ong Sok King
- Oommen Anu Mary
- Opio John Nelson
- Oren Eyal
- Oros Andrei
- Ortega-Altamirano Doris D. V.
- Ortiz Alberto
- Ortiz Justin R.
- Ortiz-Panozo Eduardo
- Ota Erika
- Otstavnov Stanislav S.
- Owolabi Mayowa O.
- Pakhale Smita
- Pakhare Abhijit
- Pan Wen-Harn
- Pana Adrian
- Panda Basant Kumar
- Panda-Jonas Songhomitra
- Pandian Jeyaraj Durai
- Papantoniou Nikolaos
- Park Eun-Kee
- Parry Charles D. H.
- Parsian Hadi
- Patel Shanti
- Pati Sanghamitra
- Patle Ajay
- Patton George C
- Paturi Vishnupriya Rao
- Paudel Deepak
- Paulson Katherine R.
- Pearce Neil
- Peprah Emmanuel
- Pereira David M.
- Perico Norberto
- Pervaiz Aslam
- Pesudovs Konrad
- Petri William A.
- Petzold Max
- Phillips Michael R.
- Phuc Huyen
- Pigott David M.
- Pillay Julian David
- Pirsaheb Meghdad
- Pletcher Martin A
- Pond Constance D.
- Postma Maarten J.
- Pourshams Akram
- Poustchi Hossein
- Prabhakaran Dorairaj
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- Prasad Narayan
- Purcell Caroline A.
- Pyakurel Manita
- Qorbani Mostafa
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- Rahman Muhammad Aziz
- Rahman Sajjad ur
- Rahman Shafiur
- Rajati Fatemeh
- Rajsic Sasa
- Ram Usha
- Rana Saleem M
- Ranabhat Chhabi Lal
- Ranjan Prabhat
- Rasella Davide
- Rawaf David Laith
- Rawaf Salman
- Razo-García Christian
- Reddy K. Srinath
- Reiner Robert C.
- Reis Cesar
- Reitsma Marissa B
- Remuzzi Giuseppe
- Renzaho Andre M. N.
- Resnikoff Serge
- Reynales-Shigematsu Luz Myriam
- Rezaei Satar
- Rezaeian Shahab
- Rezai Mohammad Sadegh
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- Ribeiro Antonio Luiz Pinho
- Rincon Julio Cesar Campuzano
- Rios-Blancas Maria Jesus
- Rivas Jacqueline Castillo
- Roba Kedir Teji
- Roberts Nicholas L S
- Roever Leonardo
- Ronfani Luca
- Roshandel Gholamreza
- Rostami Ali
- Roth Gregory A.
- Roy Ambuj
- Rubagotti Enrico
- Ruhago George Mugambage
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- Sachdev Perminder S.
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- Salimzadeh Hamideh
- Salomon Joshua A.
- Salvi Sundeep
- Salz Inbal
- Sambala Evanson Zondani
- Samy Abdallah M.
- Sanabria Juan
- Sanchez-Niño Maria Dolores
- Santos Itamar S.
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- Sawant Arundhati R.
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- Schmidt Maria Inês
- Schneider Ione Jayce Ceola
- Schutte Aletta E.
- Schwebel David C.
- Schwendicke Falk
- Schöttker Ben
- Seedat Soraya
- Sepanlou Sadaf G.
- Serván-Mori Edson
- Seyedmousavi Seyedmojtaba
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- Shrime Mark G.
- Shukla Sharvari Rahul
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- Si Si
- Siabani Soraya
- Sibai Abla M.
- Siddiqi Tariq Jamal
- Sigfusdottir Inga Dora
- Silpakit Naris
- Silva Diego Augusto Santos
- Silva João Pedro
- Silveira Dayane Gabriele Alves
- Singh Jasvinder A.
- Singh Narinder Pal
- Singh Om Prakash
- Singh Prashant
- Singh Virendra
- Sinha Dhirendra N
- Skiadaresi Eirini
- Sliwa Karen
- Smith Amanda E.
- Smith Mari
- Sobaih Badr Hasan
- Sobhani Soheila
- Soljak Michael
- Soofi Moslem
- Soosaraei Masoud
- Sorensen Reed J D
- Soriano Joan B.
- Soshnikov Sergey
- Soyiri Ireneous N.
- Spinelli Angela
- Sposato Luciano A.
- Sreeramareddy Chandrashekhar T
- Srinivasan Raghavendra Guru
- Srinivasan Vinay
- Stanaway Jeffrey D.
- Starodubov Vladimir I.
- Stathopoulou Vasiliki
- Steckling Nadine
- Stein Dan J.
- Stewart Leo G.
- Stockfelt Leo
- Stokes Mark A.
- Straif Kurt
- Sudaryanto Agus
- Sufiyan Mu'awiyyah Babale
- Sunguya Bruno F.
- Sur Patrick J
- Sutradhar Ipsita
- Sykes Bryan L.
- Sylaja P N
- Sylte Dillon O
- Szoeke Cassandra
- Tabarés-Seisdedos Rafael
- Tabuchi Takahiro
- Tadakamadla Santosh Kumar
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- Tandon Nikhil
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- Thomas Nihal
- Thomson Alan J
- Thrift Amanda G.
- Tilahun Binyam
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- Tonelli Marcello
- Topor-Madry Roman
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- Tortajada-Girbés Miguel
- Tovani-Palone Marcos Roberto
- Towbin Jeffrey A.
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- Tran Khanh Bao
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- Troeger Christopher
- Truelsen Thomas
- Tsadik Afewerki Gebremeskel
- Tuzcu E. Murat
- Tymeson Hayley D.
- Ukwaja Kingsley N.
- Ullah Irfan
- Updike Rachel L
- Usman Muhammad
- Uthman Olalekan A.
- Vaduganathan Muthiah
- Vaezi Afsane
- Vaidya Gaurang
- Valdez Pascual R.
- van Donkelaar Aaron
- Varavikova Elena
- Vasankari Tommi
- Venketasubramanian Narayanaswamy
- Vidavalur Ramesh
- Villafaina Santos
- Violante Francesco Saverio
- Vladimirov Sergey K
- Vlassov Vasily
- Vollmer Sebastian
- Vollset Stein Emil
- Vos Theo
- Vosoughi Kia
- Vujcic Isidora S.
- Wagner Gregory R.
- Wagnew Fasil
- Waheed Yasir
- Walson Judd L.
- Wang Yanping
- Wang Yuan-Pang
- Wassie Molla Mesele
- Weiderpass Elisabete
- Weintraub Robert G.
- Weiss Jordan
- Weldegebreal Fitsum
- Weldegwergs Kidu Gidey
- Werdecker Andrea
- Werkneh Adhena Ayaliew
- West T. Eoin
- Westerman Ronny
- Whisnant Joanna L
- Whiteford Harvey
- Widecka Justyna
- Widecka Katarzyna
- Wijeratne Tissa
- Wilner Lauren B.
- Winkler Andrea Sylvia
- Wiyeh Alison B.
- Wiysonge Charles Shey
- Wolde Haileab Fekadu
- Wolfe Charles D.A.
- Wu Shouling
- Xavier Denis
- Xu Gelin
- Xu Rixing
- Yadollahpour Ali
- Yakob Bereket
- Yamada Tomohide
- Yan Lijing L.
- Yano Yuichiro
- Yaseri Mehdi
- Yasin Yasin Jemal
- Ye Pengpeng
- Yearwood Jamal A.
- Yeshaneh Alex
- Yimer Ebrahim M
- Yip Paul S. F.
- Yirsaw Biruck Desalegn
- Yisma Engida
- Yonemoto Naohiro
- Yonga Gerald
- Yoon Seok Jun
- Yotebieng Marcel
- Younis Mustafa Z.
- Yousefifard Mahmoud
- Yu Chuanhua
- Zamani Mohammad
- Zare Zohreh
- Zavala-Arciniega Luis
- Zegeye Desalegn Tegabu
- Zegeye Elias Asfaw
- Zeleke Ayalew Jejaw
- Zendehdel Kazem
- Zerfu Taddese Alemu
- Zhang Anthony Lin
- Zhang Xueying
- Zhou Maigeng
- Zhu Jun
- Zimsen Stephanie R. M.
- Zodpey Sanjay
- Zoeckler Leo
- Zucker Inbar
- Zuhlke Liesel Joanna J.
- Ärnlöv Johan
- Çavlin Alanur
- Šekerija Mario
- Publication venue
- Elsevier
- Publication date
- 01/01/2018
- Field of study
© 2018 The Author(s). Background: Assessments of age-specifc mortality and life expectancy have been done by the UN Population Division, Department of Economics and Social Afairs (UNPOP), the United States Census Bureau, WHO, and as part of previous iterations of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD). Previous iterations of the GBD used population estimates from UNPOP, which were not derived in a way that was internally consistent with the estimates of the numbers of deaths in the GBD. The present iteration of the GBD, GBD 2017, improves on previous assessments and provides timely estimates of the mortality experience of populations globally. Methods: The GBD uses all available data to produce estimates of mortality rates between 1950 and 2017 for 23 age groups, both sexes, and 918 locations, including 195 countries and territories and subnational locations for 16 countries. Data used include vital registration systems, sample registration systems, household surveys (complete birth histories, summary birth histories, sibling histories), censuses (summary birth histories, household deaths), and Demographic Surveillance Sites. In total, this analysis used 8259 data sources. Estimates of the probability of death between birth and the age of 5 years and between ages 15 and 60 years are generated and then input into a model life table system to produce complete life tables for all locations and years. Fatal discontinuities and mortality due to HIV/AIDS are analysed separately and then incorporated into the estimation. We analyse the relationship between age-specifc mortality and development status using the Socio-demographic Index, a composite measure based on fertility under the age of 25 years, education, and income. There are four main methodological improvements in GBD 2017 compared with GBD 2016: 622 additional data sources have been incorporated; new estimates of population, generated by the GBD study, are used; statistical methods used in diferent components of the analysis have been further standardised and improved; and the analysis has been extended backwards in time by two decades to start in 1950. Findings: Globally, 18·7% (95% uncertainty interval 18·4-19·0) of deaths were registered in 1950 and that proportion has been steadily increasing since, with 58·8% (58·2-59·3) of all deaths being registered in 2015. At the global level, between 1950 and 2017, life expectancy increased from 48·1 years (46·5-49·6) to 70·5 years (70·1-70·8) for men and from 52·9 years (51·7-54·0) to 75·6 years (75·3-75·9) for women. Despite this overall progress, there remains substantial variation in life expectancy at birth in 2017, which ranges from 49·1 years (46·5-51·7) for men in the Central African Republic to 87·6 years (86·9-88·1) among women in Singapore. The greatest progress across age groups was for children younger than 5 years; under-5 mortality dropped from 216·0 deaths (196·3-238·1) per 1000 livebirths in 1950 to 38·9 deaths (35·6-42·83) per 1000 livebirths in 2017, with huge reductions across countries. Nevertheless, there were still 5·4 million (5·2-5·6) deaths among children younger than 5 years in the world in 2017. Progress has been less pronounced and more variable for adults, especially for adult males, who had stagnant or increasing mortality rates in several countries. The gap between male and female life expectancy between 1950 and 2017, while relatively stable at the global level, shows distinctive patterns across super-regions and has consistently been the largest in central Europe, eastern Europe, and central Asia, and smallest in south Asia. Performance was also variable across countries and time in observed mortality rates compared with those expected on the basis of development. Interpretation: This analysis of age-sex-specifc mortality shows that there are remarkably complex patterns in population mortality across countries. The fndings of this study highlight global successes, such as the large decline in under-5 mortality, which refects signifcant local, national, and global commitment and investment over several decades. However, they also bring attention to mortality patterns that are a cause for concern, particularly among adult men and, to a lesser extent, women, whose mortality rates have stagnated in many countries over the time period of this study, and in some cases are increasing
Effect of SGLT2 Inhibitors on Stroke and Atrial Fibrillation in Diabetic Kidney Disease: Results From the CREDENCE Trial and Meta-Analysis
- Author
- (Jay) Kropp Jeffrey
- Abdul Kadir Khalid
- Abdullah Raied
- Abraham Oomman India:
- Abramowitz Matthew
- Acosta Idalia
- Africa: Fayzal Ahmed South
- Agra Jeimeen
- Aiello Joseph
- Ainsworth Paul
- Aizenberg Diego
- Akright Laura
- Akyea-Djamson Ayim
- Al-Karadsheh Amer
- Alappan Rajendran
- Alberto Andreotti Turatti Luiz
- Alberto Berli Mario
- Alberto Cuneo Carlos
- Alberto Cunha V\ueancio S\ue9rgio
- Alberto Ramirez Roca Luis
- Alexandra Terront Lozano Monica
- Alfonso Leon de la Fuente Ricardo
- Ali Norsiah
- Ali Zishan
- Alicic Radica
- Alina Agafyina Russia:
- Alpizar Salazar Melchor
- Alva Hansraj
- Alvarisqueta Andres
- Amodeo Celso
- Andres Ahuad Guerrero Rodolfo
- Angel Reyes Rosano Miguel
- Angelova Angelina
- Anghel Veronica
- Angustias Quesada Sim\uf3n Mar\ueda
- Ant\uf4nio Pereira M\ue1rcio
- Antonia Munar Vila Maria
- Antonio Novoa Pablo
- Antonio S\ue1nchez Arenales Jose
- Aoki Hiromi
- Aquitania Grace
- Arauz-Pacheco Carlos
- Archibaldo Glenny Jorge
- Arcos Edgar
- Arfeen Shahabul
- Arif Ahmed
- Aronson Ronnie
- Arutchelvam Vijayaraman
- Arvind Moogali
- Asano Akimichi
- Asmarats Mercadal Luis
- Atray Naveen
- Augusto Alves da Costa Fernando
- Avendano Jorge
- Avram Rodica-Ioana
- Awad Ahmed
- Baas Cruz Juan
- Badat Aysha
- Bajaj Harpreet
- Bakris George
- Barbarash Olga
- Barnard Maria
- Barnhill Peggy
- Barranco Elizabeth
- Barrera Carlos
- Barrios Clara
- Bartolacci Ines
- Barton Petr
- Barysheva Olga
- Beacom Matthew
- Beatrice Zanata Petry Tarissa
- Beatriz Schiavi Lilia
- Behara Venkata
- Bellary Srikanth
- Belo Diogo
- Belobradkova Jana
- Bentley-Lewis Rhonda
- Benusova Olga
- Berenguer Ramon
- Berenice Saavedra Sanchez Sandra
- Bermudez Lidia
- Bernardo Marializa
- Bhajan Manocha Anita
- Bhushan Raju Sree
- Bilyk Svitlana D.
- Biscoveanu Mihaela
- Bordonava Anselmo
- Borot Sophie
- Botsyurko Volodymyr
- Bowman-Stroud Cynthia
- Brandon Donald
- Breedt Johannes
- Bregman Rachel
- Brusco Osvaldo
- Buganova Ingrid
- Burgos Soto Mario
- Busch Robert
- Busegeanu Mihaela-Magdalena
- Calella Pedro
- Canaan Yamil
- Caringal Clodoaido
- Cariou Bertrand
- Carlo Sasso Ferdinando
- Carlo Tibes Hachmann Jean
- Carlos Santos Juan
- Castellino Pietro
- Cecilia Cantero Maria
- Cecilia Coloma Gabriela
- Cercos Esteban
- Cereto Castro Fernando
- Ceriello Antonio
- Chandra Vyasam Ramesh
- Chen Qinkai
- Cherney David
- Chevaile Ramos Jose
- Chew Wong Alfredo
- Chilito Alicia
- Chiovato Luca
- Chizhov Daniil
- Chouinard Guy
- Christensen Tom
- Christiano Cynthia
- Christofides Elena
- Chuang Lee-Ming
- Chuateco Caroucel
- Chwen-Tzuei Chang Taiwan:
- Cif Adriana
- Cigarran Guldris Secundino
- Cohen Kenneth
- Cohen Robert
- Cohen- Stein Debbie
- Colombo Hugo
- Commendatore Victor
- Conway James
- Cook Charles
- Cosma Dana
- Cournoyer Serge
- Coyne Daniel
- Crawford Allison Dale
- Crisan Carmen
- Cristian Greloni Gustavo
- Cristina Camelo Sanches Fernanda
- Csiky Botond
- Cuadrado Jesus
- Culak Jan
- d'Avila Domingos
- Daboul Nizar
- Danos Peter
- Dario Dran Ricardo
- Dario Vargas Alonso Ruben
- DaRoza Gerald
- Darwish Riad
- Daswani Adarsh
- Daud Che Yusof Mohd
- David Gomez Rangel Jose
- Davies Emyr
- Davies Mark
- Davies Simon
- Dawson Alison
- De Cosmo Salvatore
- De Nicola Luca
- De Serres Sacha
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- de Souza Pedro
- Deak Laszlo
- Deck Kenneth
- del Carmen Gonzalez Colaso Patricia
- Delos Santos Lalaine
- Derosa Giuseppe
- Desouza Cyrus
- Despina Demian Luiza
- Dev Devasmita
- Dewan Deepak
- Dhillon Monika
- Di Carlo Alberto
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- Diego Higuera Juan
- Dimitrov Stefan
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- Dohnalova Lenka
- Dominguez Lopez Marta
- Dovie Lallaine Ygpuara Ma.
- Drasnar Tomas
- Dreval Alexander
- Droste Carolyn
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- Dub\ue9 Fran\ue7ois
- Dudar Iryna
- Dudas Mihaly
- Dussol Bertrand
- Dzupina Andrej
- Dzuponova Jana
- Eder Frank
- Edmundo Enriquez Sosa Favio
- Edwin Fernando M.
- Egido de los Rios Jesus
- Egle Gaupsiene Lithuania:
- El Kossi Mohsen
- El-Shahawy Mohamed
- Emilia Ferariu Ioana
- English Patrick
- Enrique Herrera Jimenez Luis
- Eric Alamartine France:
- Erika Rucker Joerg Isabel
- Ernesto Andres Diaz Ruiz Jorge
- Ervin John
- Esquenazi Alberto
- Esteban Jodar Gimeno Jose
- Esther Visco Virginia
- Ethel Yap Yvette
- Evans John
- Faghih Markus
- Farias Eduardo
- Faulmann Grit
- Fauvel Jean-Pierre
- Ferkl Richard
- Fernandez Fresnedo Gema
- Fernando Flota Cervera Luis
- Finkelstein Hernan
- Fishbane Steven
- Florencia Fernandez Maria
- Flores Lozano Fernando
- Fragale Guillermo
- Fraige Filho Fadlo
- Francisco Kerr Saraiva Jose
- Frasc\ue0 Giovanni
- Fraser Donald
- Fraser Ian
- Frenk Baron Paul
- Frias Juan
- Fuiano Giorgio
- Fulop Peter
- Fushtey Ivan
- Gabriela Onaca Adriana
- Galan Serrano Antonio
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- Galphin Claude
- Gambaro Giovanni
- Gan Shenglian
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- Garcia Isabel
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- Ghazi Adline
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- Goldenberg Ronald
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- Gracious Noble
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- Grubb Stephen
- Guillermo Douthat Walter
- Guinsburg Adrian
- Gulati Rakesh
- Gunstone Anthony
- Gupta Anil
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- Gyongyi Csecsei Hungary:
- Gyrina Olga
- H-H Sheu Wayne
- Halciakova Katarina
- Hall Timothy
- Haller Hermann
- Halmagyi Ildiko
- Hammoud Jamal
- Hancu Nicolae
- Handelsman Stuart
- Hanif Wasim
- Harcsa Eleonora
- Hartman Israel
- Hector Resk Jorge
- Hector Sanchez Mijangos Jose
- Henein Sam
- Henrique Canani Luis
- Hermida Sonia
- Hernandez Triana Eric
- Hernando Garcia Ortiz Luis
- Hershon Kenneth
- Hiser Daniel
- Hitoshi Akiyama Japan:
- Ho Yoon Kun
- Hon George
- Hoon Kim Yeong
- Horacio Garcia Nestor
- Hotlos Lucyna
- Hristozov Kiril
- Hsia Te-Lin
- Hsieh Chang-Hsun
- Hwang ShangJyh
- Iitsuka Tadashi
- Ilavska Adriana
- In\ue9s Molina de Salazar Dora
- Ines Orio Silvia
- Isabel Klyver Maria
- Isaias Juncos Luis
- Isela Luna Ceballos Rosa
- Ismail Mastura
- Jackson Alan
- Jacob Radu
- Jaime Maria
- Jain Dinesh
- Jamal Aamir
- Jana Babikova Slovakia:
- Januszewicz Andrzej
- Javier Gonzalez Martinez Francisco
- Javier Zaidman Cesar
- Jeong Kwon Min
- Jeong In-Kyung
- Jerwan-Keim Reinhold
- Jimenez Flores Fernando
- Jimeno Cecilia
- Johnson Andrew
- Johnson David
- Jorge da Silva Franco Roberto
- Jose Luis Accini Mendoza Colombia:
- Jose Tinahones Madueno Francisco
- Joseph Franklin
- Joshi Mukesh
- Jurgens Jaco
- Kaczmarek Barbara
- Kajiyama Shizuo
- Kaldun Nossuli A.
- Kamenov Zdravko
- Kaminska Anna
- Kashine Susumu
- Kaupke Charles
- Kawada Toshio
- Kazmirchuk Anatoliy
- Keightley Gerald
- Keiko Kohara Suely
- Keitel Elizete
- Keltai Katalin
- Kendereski Aleksandra
- Keresztesi Sandor
- Kern Elizabeth
- Keshavamurthy C. B.
- Khandwala Hasnain
- Khanna Rakhi
- Khirmanov Vladimir
- Khitan Zeid
- Khullar Dinesh
- Kim Sun
- Kingdom: Kamal Abouglila United
- Kiss Krisztian
- Klein Alexandre
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- Kodera Takamoto
- Kolesnyk Mykola
- Kolmakova Elena
- Komisarenko Iuliia
- Kong Yaozhong
- Kono Hiroshi
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- Kopyt Nelson
- Korea: Dong-Wan Chae South
- Koroleva Tatiana
- Korzh Oleksii
- Koundurdjiev Atanas
- Kovar Richard
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- Lin Chih-Ching
- Lin Hongli
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- Lukac Martin
- M\uf4nica Deboni Luciane
- Ma Portoles Perez Jose
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- Marar Isam
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- Narvarte Javier
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- Niiya Tetsuji
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- Rendell Marc
- Republic: Dagmar Bartaskova Czech
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- Rich Lisa
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- Roberto Chacra Ant\uf4nio
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- Ronaldo Arturo Gonzalez Orellana Guatemala:
- Rosa Ulla Maria
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- Villagordoa Mesa Juan
- Villarino Adriana
- Villegas Ivan
- Virginia Lanchiotti Paulina
- Vizir Vadym
- Vlasenko Maryna
- Volker Burst Germany:
- Vorobyev Sergey
- Vukotic Goga
- Wada Takashi
- Wadud Khurram
- Wahba Mona
- Wakasugi Masakiyo
- Wakeling John
- Wakida Yasushi
- Walker Robert
- Wang Guixia
- Warren Mark
- Wassermann Alfredo
- Watanabe Takayuki
- Watson Edward
- Watson Henry
- Watts Ronald
- Weiner Daniel
- Weiner Pavel
- Welker James
- Welsh Jean
- Wheeler David
- Williams Michael
- Williams Shelley
- Win Lam Swee
- Winocour Peter
- Woo Vincent
- y Orozco Juan Alfredo Tamayo
- Yakov Andrian
- Yamada Masayo
- Yamada S\ue9rgio
- Yanagida Kazuhiro
- Yanase Toshihiko
- Yang Jinkui
- Yao Christy
- Yen Kong Wei
- Yin Aiping
- Yoiti Hayashida Cesar
- Young Simon
- Yu Xueqing
- Yuan Lee Li
- Yumita Wataru
- Yupanqui Hernan
- Zalunardo Nadia
- Zamarripa Escobedo Rolando
- Zaniewski-Singh Michelle
- Zanoli Luca
- Zaoui Philippe
- Zateyshchikova Anna
- Zateyshshikov Dmitry
- Zaynab Abejuela Philippines:
- Zealand: John Baker New
- Zemek Stanislav
- Zhao Minghui
- Zheng Hongguang
- Zlova Tetiana
- Zsom Marianna
- Zub Liliia
- Zykova Tatyana
- Publication venue
- 'Ovid Technologies (Wolters Kluwer Health)'
- Publication date
- 01/01/2021
- Field of study
BACKGROUND AND PURPOSE: Chronic kidney disease with reduced estimated glomerular filtration rate or elevated albuminuria increases risk for ischemic and hemorrhagic stroke. This study assessed the effects of sodium glucose cotransporter 2 inhibitors (SGLT2i) on stroke and atrial fibrillation/flutter (AF/AFL) from CREDENCE (Canagliflozin and Renal Events in Diabetes With Established Nephropathy Clinical Evaluation) and a meta-analysis of large cardiovascular outcome trials (CVOTs) of SGLT2i in type 2 diabetes mellitus.METHODS: CREDENCE randomized 4401 participants with type 2 diabetes mellitus and chronic kidney disease to canagliflozin or placebo. Post hoc, we estimated effects on fatal or nonfatal stroke, stroke subtypes, and intermediate markers of stroke risk including AF/AFL. Stroke and AF/AFL data from 3 other completed large CVOTs and CREDENCE were pooled using random-effects meta-analysis.RESULTS: In CREDENCE, 142 participants experienced a stroke during follow-up (10.9/1000 patient-years with canagliflozin, 14.2/1000 patient-years with placebo; hazard ratio [HR], 0.77 [95% CI, 0.55-1.08]). Effects by stroke subtypes were: ischemic (HR, 0.88 [95% CI, 0.61-1.28]; n=111), hemorrhagic (HR, 0.50 [95% CI, 0.19-1.32]; n=18), and undetermined (HR, 0.54 [95% CI, 0.20-1.46]; n=17). There was no clear effect on AF/AFL (HR, 0.76 [95% CI, 0.53-1.10]; n=115). The overall effects in the 4 CVOTs combined were: total stroke (HRpooled, 0.96 [95% CI, 0.82-1.12]), ischemic stroke (HRpooled, 1.01 [95% CI, 0.89-1.14]), hemorrhagic stroke (HRpooled, 0.50 [95% CI, 0.30-0.83]), undetermined stroke (HRpooled, 0.86 [95% CI, 0.49-1.51]), and AF/AFL (HRpooled, 0.81 [95% CI, 0.71-0.93]). There was evidence that SGLT2i effects on total stroke varied by baseline estimated glomerular filtration rate (P=0.01), with protection in the lowest estimated glomerular filtration rate (<45 mL/min/1.73 m2]) subgroup (HRpooled, 0.50 [95% CI, 0.31-0.79]).CONCLUSIONS: Although we found no clear effect of SGLT2i on total stroke in CREDENCE or across trials combined, there was some evidence of benefit in preventing hemorrhagic stroke and AF/AFL, as well as total stroke for those with lowest estimated glomerular filtration rate. Future research should focus on confirming these data and exploring potential mechanisms. Registration: URL: https://www.clinicaltrials.gov; Unique identifier: NCT02065791
Kidney and Cardiovascular Effects of Canagliflozin According to Age and Sex: A Post Hoc Analysis of the CREDENCE Randomized Clinical Trial
- Author
- Abdallah Joseph
- Abdul Ghani Rohana
- Abdullah Raied
- Abejuela Zaynab
- Abouglila Kamal
- Abraham Oomman
- Abraira Munoz Luis David
- Abramowitz Matthew
- Abusnana Salah
- Acosta Idalia
- Agafyina Alina
- Agarwal Rajiv
- Agarwal Rajiv
- Aggarwal Naresh
- Agra Jeimeen
- Ahmad Nik Nur Fatnoon Nik
- Ahmed Fayzal
- Aiello Joseph
- Ainsworth Paul
- Aizenberg Diego
- Aizenberg Diego
- Akiyama Hitoshi
- Akright Laura
- Akyea-Djamson Ayim
- Al-Karadsheh Amer
- Alamartine Eric
- Alappan Rajendran
- Albisu Juan Pablo
- Alexandra Terront Lozano Monica
- Ali Norsiah
- Ali Zishan
- Alicic Radica
- Allison Dale Crawford
- Alvarisqueta Andres
- Amodeo Celso
- Andreeva Viktoria
- Angelescu Liliana Monica
- Angelova Angelina
- Anghel Veronica
- Antic Slobodan
- Aoki Hiromi
- Aquitania Grace
- Arauz-Pacheco Carlos
- Arcos Edgar
- Arfeen Shahabul
- Arif Ahmed
- Arnott Clare
- Aronson Ronnie
- Arutchelvam Vijayaraman
- Arvind Moogali
- Asano Akimichi
- Atray Naveen
- Avendano Jorge
- Avram Rodica-Ioana
- Awad Ahmed
- Babikova Jana
- Badat Aysha
- Bajaj Harpreet
- Baker John
- Bakris George
- Bakris George
- Bakris George
- Ballesteros Cecilia Garcia
- Barbarash Olga
- Barna Olga
- Barnard Maria
- Barnhill Peggy
- Baron Paul Frenk
- Barranco Elizabeth
- Barrera Carlos
- Barrios Clara
- Bartaskova Dagmar
- Bartolacci Ines
- Barton Petr
- Barysheva Olga
- Beacom Matthew
- Behara Venkata
- Bellary Srikanth
- Belo Diogo
- Belobradkova Jana
- Bentley-Lewis Rhonda
- Benusova Olga
- Berenguer Ramon
- Berli Mario Alberto
- Bermudez Lidia
- Bernardo Marializa
- Bhushan Raju Sree
- Bijata-Bronisz Renata
- Bilyk Svitlana D.
- Biscoveanu Mihaela
- Bonadonna Riccardo
- Bordonava Anselmo
- Borges João Lindolfo Cunha
- Borot Sophie
- Botsyurko Volodymyr
- Bowman-Stroud Cynthia
- Brandon Donald
- Breedt Johannes
- Bregman Rachel
- Brenner Barry M.
- Brusco Osvaldo
- Buganova Ingrid
- Burst Volker
- Busch Robert
- Busegeanu Mihaela-Magdalena
- Calcaneo Juan Peralta
- Calella Pedro
- Canaan Yamil
- Canani Luis Henrique
- Cannon Christopher P.
- Cannon Christopher P.
- Canonge Rafael Simo
- Cantero Maria Cecilia
- Cardoza Kathryn
- Caringal Clodoaido
- Cariou Bertrand
- Carrillo Luis Venegas
- Cartasegna Luis Rodolfo
- Casabella Tomas Smith
- Castellanos Ricardo Orozco
- Castellino Pietro
- Castro Fernando Cereto
- Cepeda Alejandro Valdes
- Cercos Esteban
- Ceriello Antonio
- Chacra Antônio Roberto
- Chae Dong-Wan
- Chae Dong-Wan
- Chandra Vyasam Ramesh
- Chang Chwen-Tzuei
- Chang Tara
- Charytan David M.
- Charytan David M.
- Charytan David M.
- Chavez Eloisa Tellez
- Che Yusof Mohd Daud
- Chen Nan
- Chen Qinkai
- Cherney David
- Cherney David
- Chertow Glenn
- Cheung Ngai Wah
- Chilito Alicia
- Chiovato Luca
- Chizhov Daniil
- Cho Young Min
- Chouinard Guy
- Christensen Tom
- Christiano Cynthia
- Christofides Elena
- Chuang Lee-Ming
- Chuateco Caroucel
- Cif Adriana
- Cohen Kenneth
- Cohen Robert
- Cohen-Stein Debbie
- Colaso Patricia del Carmen Gonzalez
- Coloma Gabriela Cecilia
- Colombo Hugo
- Cometa Luis Valderrama
- Comia Rhea Severina
- Commendatore Victor
- Contieri Fabiana Loss de Carvalho
- Conway James
- Cook Charles
- Correa Rotter Jose Ricardo
- Cosma Dana
- Costa Fernando Augusto Alves da
- Cournoyer Serge
- Coyne Daniel
- Crisan Carmen
- Cruz Juan Baas
- Csecsei Gyongyi
- Csiky Botond
- Cuadrado Jesus
- Culak Jan
- Cuneo Carlos Alberto
- Cusumano Ana Maria
- Daboul Nizar
- Danos Peter
- DaRoza Gerald
- Darwish Riad
- Daswani Adarsh
- David null
- Davies Emyr
- Davies Mark
- Davies Simon
- Dawson Alison
- de Almeida Roberto Simões
- de Brito Claudia Moreira
- De Cosmo Salvatore
- De Nicola Luca
- De Nicola Luca
- de Salazar Dora Inés Molina
- De Serres Sacha
- de Souza Pedro
- de Zeeuw Dick
- de Zeeuw Dick
- Deak Laszlo
- Deboni Luciane Mônica
- Deck Kenneth
- Deepak Dewan
- del Campo Blanco Belia Martin
- Demian Luiza Despina
- Derosa Giuseppe
- Desouza Cyrus
- Dev Devasmita
- Dhillon Monika
- Di Carlo Alberto
- Di Cianni Graziano
- Di Tanna Gian Luca
- Diaz Ruiz Jorge Ernesto Andres
- Dimitrov Stefan
- Distiller Larry
- Distiller Lawrence
- Djordjevic Miodrag
- Dobronravov Vladimir
- Dohnalova Lenka
- Douthat Walter Guillermo
- Dran Ricardo Dario
- Drasnar Tomas
- Dreval Alexander
- Dreval Alexander
- Droste Carolyn
- Dua Sohan
- Dubé François
- Dudar Iryna
- Dudas Mihaly
- Dussol Bertrand
- Dzupina Andrej
- Dzuponova Jana
- d’Avila Domingos
- Eder Frank
- Edwin Fernando M.
- Egido de los Rios Jesus
- El Kossi Mohsen
- El-Shahawy Mohamed
- Elosegui Ana Maria
- English Patrick
- Enriquez Sosa Favio Edmundo
- Ervin John
- Escalante Tonatiu Diaz
- Escobedo Rolando Zamarripa
- Esquenazi Alberto
- Evans John
- Faghih Markus
- Farias Eduardo
- Fariña Marcelo Medina
- Faulmann Grit
- Fauvel Jean-Pierre
- Felício João Soares
- Ferariu Ioana Emilia
- Ferkl Richard
- Fernandez Maria Florencia
- Filho Roberto Pecoits
- Finkelstein Hernan
- Fishbane Steven
- Flores Fernando Jimenez
- Flota Cervera Luis Fernando
- Fragale Guillermo
- Fraige Filho Fadlo
- Franco Guadalupe Morales
- Franco Roberto Jorge da Silva
- Frascà Giovanni
- Fraser Donald
- Fraser Ian
- Fresnedo Gema Fernandez
- Fretes Jose Osvaldo
- Frias Juan
- Fuiano Giorgio
- Fulop Peter
- Fushtey Ivan
- Gajardo Victor Saavedra
- Galindo-Ramos Eugenia
- Galphin Claude
- Gambaro Giovanni
- Gan Chye Lee
- Gan Shenglian
- Garcia Isabel
- Garcia Nestor Horacio
- Garcia Pere Alvarez
- Garibotto Giacomo
- Gastaldi Anibal
- Gaupsiene Egle
- Gelersztein Elizabeth
- Genadieva Veselka
- Genova-Hristova Gabriela
- Ghazi Adline
- Giorda Carlo
- Glenny Jorge Archibaldo
- Glinkina Irina
- Gnudi Luigi
- Godlevska Olga
- Goldenberg Ronald
- Golovchenko Oleksandr
- Gomes Marcus
- Gomez Rangel Jose David
- Gomez Olivert
- Gonzalez Martinez Francisco Javier
- Gonzalez Orellana Ronaldo Arturo
- Gonzalez Alexander
- Gonzalez Alfonso Soto
- Gonzalez Enrique
- Gonzalez Joaquin Pablo
- Gonzalo Godoy Jorquera Juan
- Gopalakrishnan Natarajan
- Gorson David
- Gourdy Pierre
- Govender Ravendran
- Govender Vimladhevi
- Gowda Anupama
- Goycoa Claudia
- Górriz Jose L.
- Gracious Noble
- Greco Barbara
- Greene Tom
- Greloni Gustavo Cristian
- Grineva Elena
- Grubb Stephen
- Guerrero Rodolfo Andres Ahuad
- Guinsburg Adrian
- Gulati Rakesh
- Guldris Secundino Cigarran
- Gunstone Anthony
- Gupta Anil
- Gupta Milan
- Guzman Juan Rosas
- Gyrina Olga
- Haase Franklin Paul
- Hachmann Jean Carlo Tibes
- Hadjadj Samy
- Halciakova Katarina
- Hall Timothy
- Haller Hermann
- Halmagyi Ildiko
- Hammoud Jamal
- Hancu Nicolae
- Handelsman Stuart
- Hanif Wasim
- Hansraj Alva
- Harcsa Eleonora
- Hartman Israel
- Hawley Carmel
- Hayashida Cesar Yoiti
- Heerspink Hiddo J. L.
- Heerspink Hiddo J. L.
- Heerspink Hiddo J. L.
- Henein Sam
- Hermida Sonia
- Herrera Jimenez Luis Enrique
- Hershon Kenneth
- Higuera Juan Diego
- Hiser Daniel
- Hissa Miguel Nasser
- Hon George
- Hotlos Lucyna
- Hristozov Kiril
- Hsia Te-Lin
- Hsieh Chang-Hsun
- Hwang Shang-Jyh
- Hwang Shang-Jyh
- Iglesias Javier Nieto
- Iitsuka Tadashi
- Ilavska Adriana
- Irizar Santana Sergio Saul
- Ismail Mastura
- Jackson Alan
- Jacob Radu
- Jaime Maria
- Jain Dinesh
- Jamal Aamir
- Januszewicz Andrzej
- Jardine Meg
- Jardine Meg
- Jardine Meg J.
- Jeong In-Kyung
- Jerwan-Keim Reinhold
- Jha Vivekanand
- Ji Linong
- Jimeno Cecilia
- Jodar Gimeno Jose Esteban
- Johnson Andrew
- Johnson David
- Joseph Franklin
- Joshi Mukesh
- Juarez Erick Turcios
- Juncos Luis Isaias
- Junior Renan Montenegro
- Jurgens Jaco
- Kaczmarek Barbara
- Kadir Khalid Abdul
- Kajiyama Shizuo
- Kamenov Zdravko
- Kaminska Anna
- Kang Amy
- Kashine Susumu
- Kaupke Charles
- Kawada Toshio
- Kazmirchuk Anatoliy
- Keightley Gerald
- Keitel Elizete
- Keltai Katalin
- Kendereski Aleksandra
- Keresztesi Sandor
- Kern Elizabeth
- Keshavamurthy C. B.
- Khandwala Hasnain
- Khanna Rakhi
- Khirmanov Vladimir
- Khitan Zeid
- Khullar Dinesh
- Kim Sin Gon
- Kim Sun
- Kim Yeong Hoon
- Kiss Krisztian
- Klein Alexandre
- Klokocnikova Vera
- Klyver Maria Isabel
- Kodera Takamoto
- Kohara Suely Keiko
- Kolesnyk Inna
- Kolesnyk Mykola
- Kolesnyk Mykola
- Kolmakova Elena
- Komisarenko Iuliia
- Kong Wei Yen
- Kong Yaozhong
- Kono Hiroshi
- Konyves Laszlo
- Kopyt Nelson
- Koroleva Tatiana
- Korzh Oleksii
- Koundurdjiev Atanas
- Kovar Richard
- Kovesdy Csaba
- Koyama Kazunori
- Kozloviene Dalia
- Kraft Florencia
- Krane Vera
- Kravchun Nonna
- Krishna Gopal
- Krishnan Singhan
- Kropp Jeffrey (Jay)
- Krynski Fernando
- Kumar Amrendra
- Kumar Jayant
- Kumar Neil
- Kumeda Yasuro
- Kumwenda Mick
- Kusnir Jorge
- Kvitkova Liudmila
- Kwon Hyuk-Sang
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- Miyauchi Shozo
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- Moreno Loza Oscar Tarsicio
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- Tinahones Madueno Francisco Jose
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- Updegrove John
- Urbanaviciene Egle
- Uriasyev Oleg
- Valdez Maria
- Valenzuela Alex
- Valis Martin
- Vallejos Augusto
- Van Buren Peter
- Vangel Sandor
- Vannorsdall Mark
- Vargas Alonso Ruben Dario
- Varghese Freemu
- Vasas Szilard
- Vazelov Evgueniy
- Vejar Margarita
- Velasquez-Mieyer Pedro
- Velichkova Ekaterina
- Vengadasalam Paranthaman
- Ventrapragada Sailaja
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- Vera Merce Perez
- Veronelli Anna Maria
- Vêncio Sérgio Alberto Cunha
- Villarino Adriana
- Villegas Ivan
- Visco Virginia Esther
- Vizir Vadym
- Vlasenko Maryna
- Vorobyev Sergey
- Vukotic Goga
- Wada Takashi
- Wada Takashi
- Wadud Khurram
- Wahba Mona
- Wakasugi Masakiyo
- Wakeling John
- Wakida Yasushi
- Walker Robert
- Wang Guixia
- Warren Mark
- Wassermann Alfredo
- Watanabe Takayuki
- Watson Edward
- Watson Henry
- Watts Ronald
- Weiner Daniel
- Weiner Pavel
- Welker James
- Welsh Jean
- Wheeler C.
- Wheeler David
- Wheeler David C.
- Wheeler David C.
- Williams Michael
- Williams Shelley
- Winocour Peter
- Wong Alfredo Chew
- Woo Vincent
- Yakov Andrian
- Yamada Masayo
- Yamada Sérgio
- Yanagida Kazuhiro
- Yanase Toshihiko
- Yang Jinkui
- Yao Christy
- Yap Yvette Ethel
- Yi Tae Won
- Yin Aiping
- Yoon Kun Ho
- Young Simon
- Yu Xueqing
- Yumita Wataru
- Yupanqui Hernan
- Zaidman Cesar Javier
- Zalunardo Nadia
- Zanella Maria Teresa
- Zaniewski-Singh Michelle
- Zanoli Luca
- Zaoui Philippe
- Zateyshchikova Anna
- Zateyshshikov Dmitry
- Zemek Stanislav
- Zhang Hong
- Zhang Hong
- Zhang Hong
- Zhao Minghui
- Zheng Hongguang
- Zinman Bernard
- Zinman Bernard
- Zlova Tetiana
- Zsom Marianna
- Zub Liliia
- Zykova Tatyana
- Publication venue
- Publication date
- 01/01/2023
- Field of study
Rationale & Objective: It is unclear whether the effect of canagliflozin on adverse kidney and cardiovascular events in those with diabetic kid-ney disease varies by age and sex. We assessed the effects of canagliflozin among age group categories and between sexes in the Canagli-flozin and Renal Endpoints in Diabetes with Established Nephropathy Clinical Evaluation (CREDENCE) study.Study Design: Secondary analysis of a random-ized controlled trial. Setting & Participants: Participants in the CREDENCE trial. Intervention: Participants were randomly assigned to receive canagliflozin 100 mg/d or placebo.Outcomes: Primary composite outcome of kid-ney failure, doubling of serum creatinine con-centration, or death due to kidney or cardiovascular disease. Prespecified secondary and safety outcomes were also analyzed. Out-comes were evaluated by age at baseline (<60, 60-69, and >_70 years) and sex in the intention-to-treat population using Cox regression models.Results: The mean age of the cohort was 63.0 & PLUSMN; 9.2 years, and 34% were female. Older age and female sex were independently associ-ated with a lower risk of the composite of adverse kidney outcomes. There was no evidence that the effect of canagliflozin on the primary outcome (acomposite of kidney failure, a doubling of serum creatinine concentration, or death from kidney or cardiovascular causes) differed between age groups (HRs, 0.67 [95% CI, 0.52-0.87], 0.63 [0.4 8-0.82], and 0.89 [0.61-1.29] for ages <60, 60-69, and >_70 years, respectively; P = 0.3 for interaction) or sexes (HRs, 0.71 [95% CI, 0.5 4-0.95] and 0.69 [0.56-0.8 4] in women and men, respectively; P = 0.8 for interaction). No differences in safety outcomes by age group or sex were observed.Limitations: This was a post hoc analysis with multiple comparisons.Conclusions: Canagliflozin consistently reduced the relative risk of kidney events in people with diabetic kidney disease in both sexes and across age subgroups. As a result of greater background risk, the absolute reduction in adverse kidney outcomes was greater in younger participants.Funding: This post hoc analysis of the CREDENCE trial was not funded. The CREDENCE study was sponsored by Janssen Research and Development and was conducted collaboratively by the sponsor, an academic-led steering committee, and an academic research organization, George Clinical.Trial Registration: The original CREDENCE trial was registered at ClinicalTrials.gov with study number NCT02065791
International trends in clinical characteristics and oral anticoagulation treatment for patients with atrial fibrillation: Results from the GARFIELD-AF, ORBIT-AF I, and ORBIT-AF II registries
- Author
- A'Court C.
- Aaroe H.
- Abd El-Aziz A.
- Abdalla Saad J.
- Abdel-Qader M.
- Abdelrahman H.
- Abdul A.
- Abe M. (Masahiko)
- Abe M. (Masatake)
- Abe M. (Mitsunori)
- Abe S.
- Abe Y.
- Abhayaratna W.
- Abou Seif S. K.
- Abraham S.
- Abu-Mahfouz M.
- Abushal S.
- Accogli M.
- Adachi S.
- Adachi S. (Sen)
- Adachi S. (Susumu)
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- Publication venue
- 'Elsevier BV'
- Publication date
- 01/12/2017
- Field of study
Background Atrial fibrillation (AF) is the most common cardiac arrhythmia in the world. We aimed to provide comprehensive data on international patterns of AF stroke prevention treatment
International trends in clinical characteristics and oral anticoagulation treatment for patients with atrial fibrillation: Results from the GARFIELD-AF, ORBIT-AF I, and ORBIT-AF II registries
- Author
- A'Court C.
- Aaroe H.
- Abd El-Aziz A.
- Abdalla Saad J.
- Abdel-Qader M.
- Abdelrahman H.
- Abdul A.
- Abe M. (Masahiko)
- Abe M. (Masatake)
- Abe M. (Mitsunori)
- Abe S.
- Abe Y.
- Abhayaratna W.
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- Adachi S. (Sen)
- Adachi S. (Susumu)
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- Publication venue
- 'Elsevier BV'
- Publication date
- 05/03/2021
- Field of study
Background Atrial fibrillation (AF) is the most common cardiac arrhythmia in the world. We aimed to provide comprehensive data on international patterns of AF stroke prevention treatment