Isothermic and Kinetic Study on Removal of Methylene Blue Dye Using Anisomeles malabarica Silver Nanoparticles: An Efficient Adsorbent to Purify Dye-Contaminated Wastewater

Remediation of industrial discharged dyes to the water bodies is much needed in the current scenario. Here in this, we prepared silver nanoparticles using Anisomeles malabarica. The synthesized nanoparticles were characterized by Fourier transform infrared study, scanning electron microscopy, dynamic scanning calorimetry, and thermogravimetric analysis. All the characterization studies suggested that the formation of silver nanoparticles was successful. The synthesized silver nanoparticles were used as an adsorbent to adsorb the methylene blue. To achieve this, optimum pH of the adsorbent to adsorb the dye was studied, and it was found to be pH 7. The adsorbent dose to adsorb the dye was found to be 0.1 g/L. From the isotherm theoretical studies, it was found that the adsorption isotherm follows Langmuir adsorption, and the qmax was found to be 97.08. From the kinetic study, the rate of the reaction follows the pseudosecond-order kinetics with regression>0.9. From the study, it was inferred the nanoparticles synthesized can act as a good adsorbent and can be used to purify the wastewater contaminated with methylene blue

Cellular models and therapies for age-related macular degeneration

Age-related macular degeneration (AMD) is a complex neurodegenerative visual disorder that causes profound physical and psychosocial effects. Visual impairment in AMD is caused by the loss of retinal pigmented epithelium (RPE) cells and the light-sensitive photoreceptor cells that they support. There is currently no effective treatment for the most common form of this disease (dry AMD). A new approach to treating AMD involves the transplantation of RPE cells derived from either human embryonic or induced pluripotent stem cells. Multiple clinical trials are being initiated using a variety of cell therapies. Although many animal models are available for AMD research, most do not recapitulate all aspects of the disease, hampering progress. However, the use of cultured RPE cells in AMD research is well established and, indeed, some of the more recently described RPE-based models show promise for investigating the molecular mechanisms of AMD and for screening drug candidates. Here, we discuss innovative cell-culture models of AMD and emerging stem-cell-based therapies for the treatment of this vision-robbing disease