427 research outputs found
Hydrolysis of the Leu-Gly bond of phenylazobenzyl-oxycarbonyl- l -Pro- l -Leu-Gly- l -Pro- D -Arg (a substrate of microbial collagenases) by treponemes isolated from the subgingival plaque of periodontitis patients
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/1990
- Field of study
Cell extracts prepared from several oral treponemes isolated from the subgingival plaque of periodontitis patients showed high enzyme activity toward phenylazobenzyl-oxycarbonyl- l -prolyl- l -leucylglycyl- l -prolyl- d -arginine (a compound used as a substrate for microbial collagenases). One major enzyme hydrolyzing this substrate at the Leu-Gly bond only was partially purified from an unspeciated treponeme (strain US), Treponema denticola ATCC 35405, and 29 different clinical isolates of T. denticola . The Treponema US enzyme also hydrolyzed furylacryloyl- l -leucylglycyl- l -prolyl- l -alanine (another substrate of bacterial collagenases) at the Leu-Gly bond. This enzyme also hydrolyzed various collagens and collagen-derived peptides. These treponemal proteases were sensitive to metal chelators and p -chloromercury compounds. The results indicate that human oral treponemes contain enzymes that readily hydrolyze in chromogenic protease substrates the Leu-Gly bond only that is the cleavage site of these substrates also by âtrueâ microbial collagenases.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/41336/1/284_2005_Article_BF02094028.pd
Mindfulness-Based Cognitive Therapy (MBCT) programme for depression in people with early stages of dementia: study protocol for a randomised controlled feasibility study
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Comparative study of enteric viruses, coliphages and indicator bacteria for evaluating water quality in a tropical high-altitude system
- Author
- A Rzezutka
- AC Espinosa
- AE Duran
- Ana C Espinosa
- APHA
- B Foley
- B Jiménez
- C Gerba
- C Gerba
- Carlos F Arias
- CJ Hurst
- CW LeBaron
- DN Pavlov
- DOF
- DOF
- DOF
- DOF
- E MĂ©ndez
- F Baggi
- F LeGuyader
- FX Abad
- GA Burlingame
- GA Shin
- GA Toranzos
- GD Mandilara
- GDF
- GJ Medema
- H Yoshida
- I Barcina
- J Hewitt
- JE Walter
- JJ Borrego
- JJ Calva
- JL Liang
- JS Noel
- KK Chao
- L Gofti-Laroche
- L Guerrero
- M Koopmans
- M Mazari-Hiriart
- MA Borchardt
- Marisa Mazari-Hiriart
- MJ Crawley
- MJ Crawley
- NJ Ashbolt
- P Jiménez
- RA Raphael
- RJ Davies-Colley
- RL Ward
- S Skraber
- S Villa
- Salvador SĂĄnchez-ColĂłn
- SM Matsui
- T Blair
- UD Parashar
- WAM Hijnen
- World Health Organization
- Y LĂłpez-Vidal
- Publication venue
- BioMed Central
- Publication date
- 01/01/2009
- Field of study
<p>Abstract</p> <p>Background</p> <p>Bacteria used as indicators for pathogenic microorganisms in water are not considered adequate as enteric virus indicators. Surface water from a tropical high-altitude system located in Mexico City that receives rainwater, treated and non-treated wastewater used for irrigation, and groundwater used for drinking, was studied.</p> <p>Methods</p> <p>The presence of enterovirus, rotavirus, astrovirus, coliphage, coliform bacteria, and enterococci was determined during annual cycles in 2001 and 2002. Enteric viruses in concentrated water samples were detected by reverse transcriptase-polymerase chain reaction (RT-PCR). Coliphages were detected using the double agar layer method. Bacteria analyses of the water samples were carried out by membrane filtration.</p> <p>Results</p> <p>The presence of viruses and bacteria in the water used for irrigation showed no relationship between current bacterial indicator detection and viral presence. Coliphages showed strong association with indicator bacteria and enterovirus, but weak association with other enteric viruses. Enterovirus and rotavirus showed significant seasonal differences in water used for irrigation, although this was not clear for astrovirus.</p> <p>Conclusion</p> <p>Coliphages proved to be adequate faecal pollution indicators for the irrigation water studied. Viral presence in this tropical high-altitude system showed a similar trend to data previously reported for temperate zones.</p
Direct association between pharyngeal viral secretion and host cytokine response in severe pandemic influenza
- Author
- AG Smith
- Ana Loza
- Andres Anton
- AP Kendal
- BA Lennette ET
- C Agrati
- C Ramsey
- Carmen Castro
- CM Cameron
- CR Baskin
- Cristobal LeĂłn
- David Andaluz
- David Banner
- David J Kelvin
- E Bautista
- E Maravi-Poma
- Enrique Maravi
- Felipe Bobillo
- Fernando Martin-Sanchez
- Francisco GandĂa
- G Pavlisa
- Guillermo Lopez-Campos
- I Martin-Loeches
- Ignacio Martin-Loeches
- Jesus F Bermejo-Martin
- JesĂșs Blanco
- JF Bermejo-Martin
- JF Bermejo-Martin
- Jordi Rello
- Jose MÂȘ Eiros
- JS Peiris
- K Suwannakarn
- KK To
- Longsi Ran
- Lorenzo Socias
- Luoling Xu
- M Giannella
- M Ratta
- Maria C Gallegos
- Maria Ăngeles Marcos
- MD de Jong
- Milagros Gonzalez-Rivera
- MJ Cameron
- MJ Kang
- MM Kilani
- MĂłnica GordĂłn
- N Hagau
- N Lee
- N Lee
- N Uchide
- N Venteclef
- ND Powell
- Paula Mateo
- Paula Ramirez
- Pedro Merino
- Raquel Almansa
- Raul Ortiz de Lejarazu
- RM Strieter
- Salvador Resino
- SH Kim
- SJ Drews
- T Hamza
- T Jaecklin
- TomĂĄs Pumarola
- Victoria Fernandez
- Publication venue
- BioMed Central
- Publication date
- 01/01/2011
- Field of study
<p>Abstract</p> <p>Background</p> <p>Severe disease caused by 2009 pandemic influenza A/H1N1virus is characterized by the presence of hypercytokinemia. The origin of the exacerbated cytokine response is unclear. As observed previously, uncontrolled influenza virus replication could strongly influence cytokine production. The objective of the present study was to evaluate the relationship between host cytokine responses and viral levels in pandemic influenza critically ill patients.</p> <p>Methods</p> <p>Twenty three patients admitted to the ICU with primary viral pneumonia were included in this study. A quantitative PCR based method targeting the M1 influenza gene was developed to quantify pharyngeal viral load. In addition, by using a multiplex based assay, we systematically evaluated host cytokine responses to the viral infection at admission to the ICU. Correlation studies between cytokine levels and viral load were done by calculating the Spearman correlation coefficient.</p> <p>Results</p> <p>Fifteen patients needed of intubation and ventilation, while eight did not need of mechanical ventilation during ICU hospitalization. Viral load in pharyngeal swabs was 300 fold higher in the group of patients with the worst respiratory condition at admission to the ICU. Pharyngeal viral load directly correlated with plasma levels of the pro-inflammatory cytokines IL-6, IL-12p70, IFN-Îł, the chemotactic factors MIP-1ÎČ, GM-CSF, the angiogenic mediator VEGF and also of the immuno-modulatory cytokine IL-1ra (p < 0.05). Correlation studies demonstrated also the existence of a significant positive association between the levels of these mediators, evidencing that they are simultaneously regulated in response to the virus.</p> <p>Conclusions</p> <p>Severe respiratory disease caused by the 2009 pandemic influenza virus is characterized by the existence of a direct association between viral replication and host cytokine response, revealing a potential pathogenic link with the severe disease caused by other influenza subtypes such as H5N1.</p
Functional Brain Networks Develop from a âLocal to Distributedâ Organization
- Author
- AL Cohen
- Alexander L. Cohen
- AM Kelly
- AP Field
- AZ Snyder
- B Biswal
- B Karrer
- B Luna
- B Luna
- BA Brody
- BE Swartz
- BJ Casey
- BL Schlaggar
- Bradley L. Schlaggar
- CF Beckmann
- D Meunier
- DA Fair
- DA Fair
- DA Fair
- DA Fair
- DA Fair
- DA Fair
- DA Leopold
- Damien A. Fair
- DJ Felleman
- DJ Price
- DJ Watts
- EA Crone
- ER Sowell
- F Miezin
- F Varela
- Francis M. Miezin
- FX Castellanos
- G Bi
- GL Shulman
- H Berger
- H Berger
- HC Kang
- JA Church
- Jessica A. Church
- JL Conel
- JL Lancaster
- JM Fuster
- Jonathan D. Power
- JR Andrews-Hanna
- JS Damoiseaux
- K Kamada
- KK Wenger
- L Luo
- LC Katz
- M D'Esposito
- M Hampson
- M Meila
- M Sur
- MA Just
- MD Fox
- MD Fox
- MD Greicius
- MD Greicius
- ME Newman
- ME Raichle
- ME Raichle
- MF Mason
- MH Johnson
- MH Johnson
- MH Johnson
- MH Johnson
- MJ Lowe
- MS Lidow
- Nico U. F. Dosenbach
- NU Dosenbach
- NU Dosenbach
- NU Dosenbach
- O Sporns
- O Sporns
- Olaf Sporns
- P Fransson
- P Fransson
- P Levitt
- P Moses
- PE Flechsig
- PR Huttenlocher
- PR Huttenlocher
- PR Huttenlocher
- R Caton
- R Salvador
- R Salvador
- R Srinivasan
- RL Buckner
- S Achard
- S Bender-deMoll
- S Durston
- SA Bunge
- SJ Gilbert
- SO Ebbesson
- Steven E. Petersen
- T Paus
- TT Brown
- W Lin
- WD Gaillard
- WH Miltner
- WM Cowan
- WT Greenough
- WW Seeley
- Y Benjamini
- Y Nir
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2009
- Field of study
The mature human brain is organized into a collection of specialized functional networks that flexibly interact to support various cognitive functions. Studies of development often attempt to identify the organizing principles that guide the maturation of these functional networks. In this report, we combine resting state functional connectivity MRI (rs-fcMRI), graph analysis, community detection, and spring-embedding visualization techniques to analyze four separate networks defined in earlier studies. As we have previously reported, we find, across development, a trend toward âsegregationâ (a general decrease in correlation strength) between regions close in anatomical space and âintegrationâ (an increased correlation strength) between selected regions distant in space. The generalization of these earlier trends across multiple networks suggests that this is a general developmental principle for changes in functional connectivity that would extend to large-scale graph theoretic analyses of large-scale brain networks. Communities in children are predominantly arranged by anatomical proximity, while communities in adults predominantly reflect functional relationships, as defined from adult fMRI studies. In sum, over development, the organization of multiple functional networks shifts from a local anatomical emphasis in children to a more âdistributedâ architecture in young adults. We argue that this âlocal to distributedâ developmental characterization has important implications for understanding the development of neural systems underlying cognition. Further, graph metrics (e.g., clustering coefficients and average path lengths) are similar in child and adult graphs, with both showing âsmall-worldâ-like properties, while community detection by modularity optimization reveals stable communities within the graphs that are clearly different between young children and young adults. These observations suggest that early school age children and adults both have relatively efficient systems that may solve similar information processing problems in divergent ways
MicroRNA Profiling of BRCA1/2 Mutation-Carrying and Non-Mutation-Carrying High-Grade Serous Carcinomas of Ovary
- Author
- A Esquela-Kerscher
- A Grimson
- AK Folkins
- Amanda Ewart Toland
- Andrew H. Beck
- BJ Milner
- BP Lewis
- C Mayr
- C. Blake Gilks
- CB Gilks
- Cheng-Han Lee
- CJ O'Neill
- CP Crum
- CP Crum
- David Huntsman
- DC Corney
- DC Corney
- DW Kindelberger
- E Bandres
- EJ Nam
- F Meng
- G Sherlock
- G Singer
- GA Calin
- GX Tong
- H Hermeking
- H Yang
- IA Asangani
- Inigo Espinosa
- J Kupryjanczyk
- J Lu
- J Shen
- Janine Senz
- JE Hirst
- JS Morey
- JZ Press
- K Levanon
- KK Zorn
- L Dubeau
- L He
- L He
- L Zhang
- M Esteller
- M Kobel
- M Ozen
- M Shih Ie
- M Thrall
- MA Valencia-Sanchez
- Matt van de Rijn
- MB Eisen
- MV Iorio
- MV Iorio
- MZ Michael
- N Dahiya
- P Landgraf
- RF Chuaqui
- RI Gregory
- S Salvador
- S Subramanian
- SA Cannistra
- Shirley X. Zhu
- SK Wyman
- Subbaya Subramanian
- T Pal
- VB Sampson
- VG Tusher
- W Etienne
- W Zhang
- WC Cho
- Y Akao
- Y Akao
- Publication venue
- Public Library of Science
- Publication date
- 01/10/2009
- Field of study
BACKGROUND:MicroRNAs (miRNA) are 20 approximately 25 nucleotide non-coding RNAs that inhibit the translation of targeted mRNA, and they have been implicated in the development of human malignancies. High grade serous ovarian carcinomas, the most common and lethal subtype of ovarian cancer, can occur sporadically or in the setting of BRCA1/2 syndromes. Little is known regarding the miRNA expression profiles of high grade serous carcinoma in relation to BRCA1/2 status, and compared to normal tubal epithelium, the putative tissue of origin for high grade serous carcinomas. METHODOLOGY/PRINCIPAL FINDINGS:Global miRNA expression profiling was performed on a series of 33 high grade serous carcinomas, characterized with respect to BRCA1/2 status (mutation, epigenetic silencing with loss of expression or normal), and with clinical follow-up, together with 2 low grade serous carcinomas, 2 serous borderline tumors, and 3 normal fallopian tube samples, using miRNA microarrays (328 human miRNA). Unsupervised hierarchical clustering based on miRNA expression profiles showed no clear separation between the groups of carcinomas with different BRCA1/2 status. There were relatively few miRNAs that were differentially expressed between the genotypic subgroups. Comparison of 33 high grade serous carcinomas to 3 normal fallopian tube samples identified several dysregulated miRNAs (false discovery rate <5%), including miR-422b and miR-34c. Quantitative RT-PCR analysis performed on selected miRNAs confirmed the pattern of differential expression shown by microarray analysis. Prognostically, lower level miR-422b and miR-34c in high grade serous carcinomas were both associated with decreased disease-specific survival by Kaplan-Meier analysis (p<0.05). CONCLUSIONS/SIGNIFICANCE:High grade serous ovarian carcinomas with and without BRCA1/2 abnormalities demonstrate very similar miRNA expression profiles. High grade serous carcinomas as a group exhibit significant miRNA dysregulation in comparison to tubal epithelium and the levels of miR-34c and miR-422b appear to be prognostically important
Search for dark matter produced in association with bottom or top quarks in âs = 13 TeV pp collisions with the ATLAS detector
- Author
- Aaboud Morad
- Aad Georges
- Abbott Brad
- Abdinov Ovsat
- Abeloos Baptiste
- Abidi Syed
- AbouZeid Ossama
- Abraham Nicola
- Abramowicz Halina
- Abreu Henso
- Abreu Ricardo
- Abulaiti Yiming
- Acharya Bobby
- Adachi Shunsuke
- Adamczyk Leszek
- Adelman Jahred
- Adersberger Michael
- Adye Tim
- Affolder Tony
- Afik Yoav
- Agatonovic-Jovin Tatjana
- Agheorghiesei Catalin
- Aguilar-Saavedra Juan
- Ahlen Steven
- Ahmadov Faig
- Aielli Giulio
- Akatsuka Shunichi
- Akerstedt Henrik
- Akilli Ece
- Akimov Andrei
- Alberghi Gian
- Albert Justin
- Albicocco Pietro
- Alconada Verzini Maria
- Alderweireldt Sara
- Aleksa Martin
- Aleksandrov Igor
- Alexa Calin
- Alexander Gideon
- Alexopoulos Theodoros
- Alhroob Muhammad
- Ali Babar
- Aliev Malik
- Alimonti Gianluca
- Alison John
- Alkire Steven
- Allbrooke Benedict
- Allen Benjamin
- Allport Phillip
- Aloisio Alberto
- Alonso Alejandro
- Alonso Francisco
- Alpigiani Cristiano
- Alshehri Azzah
- Alstaty Mahmoud
- Alvarez Gonzalez Barbara
- Alviggi Mariagrazia
- Amadio Brian
- Amaral Coutinho Yara
- Amelung Christoph
- Amidei Dante
- Amor Dos Santos Susana
- Amoroso Simone
- Anastopoulos Christos
- Ancu Lucian
- Andari Nansi
- Andeen Timothy
- Anders Christoph
- Anders John
- Anderson Kelby
- Andreazza Attilio
- Andrei George
- Angelidakis Stylianos
- Angelozzi Ivan
- Angerami Aaron
- Anisenkov Alexey
- Anjos Nuno
- Annovi Alberto
- Antel Claire
- Antonelli Mario
- Antonov Alexey
- Antrim Daniel
- Anulli Fabio
- Aoki Masato
- Aperio Bella Ludovica
- Arabidze Giorgi
- Arai Yasuo
- Araque Juan
- Araujo Ferraz Victor
- Arce Ayana
- Ardell Rose
- Arduh Francisco
- Arguin Jean-Francois
- Argyropoulos Spyridon
- Arik Metin
- Armbruster Aaron
- Armitage Lewis
- Arnaez Olivier
- Arnold Hannah
- Arratia Miguel
- Arslan Ozan
- Artamonov Andrei
- Artoni Giacomo
- Artz Sebastian
- Asai Shoji
- Asbah Nedaa
- Ashkenazi Adi
- Asquith Lily
- Assamagan Ketevi
- Astalos Robert
- Atkinson Markus
- Atlay Naim
- Augsten Kamil
- Avolio Giuseppe
- Axen Bradley
- Ayoub Mohamad
- Azuelos Georges
- Baas Alessandra
- Baca Matthew
- Bachacou Henri
- Bachas Konstantinos
- Backes Moritz
- Bagnaia Paolo
- Bahmani Marzieh
- Bahrasemani Sina
- Baines John
- Bajic Milena
- Baker Oliver
- Bakker Pepijn
- Baldin Evgenii
- Balek Petr
- Balli Fabrice
- Balunas William
- Banas Elzbieta
- Bandyopadhyay Anjishnu
- Banerjee Swagato
- Bannoura Arwa
- Barak Liron
- Barberio Elisabetta
- Barberis Dario
- Barbero Marlon
- Barillari Teresa
- Barisits Martin-Stefan
- Barkeloo Jason
- Barklow Timothy
- Barlow Nick
- Barnes Sarah
- Barnett Bruce
- Barnett Michael
- Barnovska-Blenessy Zuzana
- Baroncelli Antonio
- Barone Gaetano
- Barr Alan
- Barranco Navarro Laura
- Barreiro GuimarĂŁes da Costa JoĂŁo
- Barreiro Fernando
- Barros Vale Maria
- Bartoldus Rainer
- Barton Adam
- Bartos Pavol
- Basalaev Artem
- Bassalat Ahmed
- Bates Richard
- Batista Santiago
- Batley Richard
- Battaglia Marco
- Bauce Matteo
- Bauer Florian
- Bawa Harinder
- Beacham James
- Beattie Michael
- Beau Tristan
- Beauchemin Pierre-Hugues
- Bechtle Philip
- Beck Hans~Peter
- Beck Helge
- Becker Kathrin
- Becker Maurice
- Becot Cyril
- Beddall Andrew
- Beddall Ayda
- Bednyakov Vadim
- Bedognetti Matteo
- Bee Christopher
- Beermann Thomas
- Begalli Marcia
- Begel Michael
- Behr Janna
- Bell Andrew
- Bella Gideon
- Bellagamba Lorenzo
- Bellerive Alain
- Bellomo Massimiliano
- Belotskiy Konstantin
- Beltramello Olga
- Belyaev Nikita
- Benary Odette
- Benchekroun Driss
- Bender Michael
- Benekos Nektarios
- Benhammou Yan
- Benhar Noccioli Eleonora
- Benitez Jose
- Benjamin Douglas
- Benoit Mathieu
- Bensinger James
- Bentvelsen Stan
- Beresford Lydia
- Beretta Matteo
- Berge David
- Bergeaas Kuutmann Elin
- Berger Nicolas
- Bergsten Laura
- Beringer JĂŒrg
- Berlendis Simon
- Bernard Nathan
- Bernardi Gregorio
- Bernius Catrin
- Bernlochner Florian
- Berry Tracey
- Berta Peter
- Bertella Claudia
- Bertoli Gabriele
- Bertram Iain
- Bertsche Carolyn
- Besjes Geert-Jan
- Bessidskaia Bylund Olga
- Bessner Martin
- Besson Nathalie
- Bethani Agni
- Bethke Siegfried
- Betti Alessandra
- Bevan Adrian
- Beyer Julien-christopher
- Bianchi Riccardo-Maria
- Biebel Otmar
- Biedermann Dustin
- Bielski Rafal
- Bierwagen Katharina
- Biesuz Nicolo
- Biglietti Michela
- Billoud Thomas
- Bilokon Halina
- Bindi Marcello
- Bingul Ahmet
- Bini Cesare
- Biondi Silvia
- Bisanz Tobias
- Bittrich Carsten
- Bjergaard David
- Black James
- Black Kevin
- Blair Robert
- Blazek Tomas
- Bloch Ingo
- Blocker Craig
- Blue Andrew
- Blumenschein Ulrike
- Blunier Sylvain
- Bobbink Gerjan
- Bobrovnikov Victor
- Bocchetta Simona
- Bocci Andrea
- Bock Christopher
- Boehler Michael
- Boerner Daniela
- Bogavac Danijela
- Bogdanchikov Alexander
- Bohm Christian
- Boisvert Veronique
- Bokan Petar
- Bold Tomasz
- Boldyrev Alexey
- Bolz Arthur
- Bomben Marco
- Bona Marcella
- Boonekamp Maarten
- Borisov Anatoly
- Borissov Guennadi
- Bortfeldt Jonathan
- Bortoletto Daniela
- Bortolotto Valerio
- Boscherini Davide
- Bosman Martine
- Bossio Sola Jonathan
- Boudreau Joseph
- Bouhova-Thacker Evelina
- Boumediene Djamel
- Bourdarios Claire
- Boutle Sarah
- Boveia Antonio
- Boyd James
- Boyko Igor
- Bozson Adam
- Bracinik Juraj
- Brandt Andrew
- Brandt Gerhard
- Brandt Oleg
- Braren Frued
- Bratzler Uwe
- Brau Benjamin
- Brau James
- Breaden Madden William
- Brendlinger Kurt
- Brennan Amelia
- Brenner Lydia
- Brenner Richard
- Bressler Shikma
- Briglin Daniel
- Bristow Timothy
- Britton Dave
- Britzger Daniel
- Brochu Frederic
- Brock Ian
- Brock Raymond
- Brooijmans Gustaaf
- Brooks Timothy
- Brooks William
- Brosamer Jacquelyn
- Brost Elizabeth
- Broughton James
- Bruckman de Renstrom Pawel
- Bruncko Dusan
- Bruni Alessia
- Bruni Graziano
- Bruni Lucrezia
- Bruno Salvatore
- Brunt Benjamin
- Bruschi Marco
- Bruscino Nello
- Bryant Patrick
- Bryngemark Lene
- Buanes Trygve
- Buat Quentin
- Buchholz Peter
- Buckley Andrew
- Budagov Ioulian
- Buehrer Felix
- Bugge Magnar
- Bulekov Oleg
- Bullock Daniel
- Burch Tyler
- Burdin Sergey
- Burgard Carsten
- Burger Angela
- Burghgrave Blake
- Burka Klaudia
- Burke Stephen
- Burmeister Ingo
- Burr Jonathan
- Bussey Peter
- Butler John
- Buttar Craig
- Butterworth Jonathan
- Butti Pierfrancesco
- Buttinger William
- Buzatu Adrian
- Buzykaev Aleksey
- BĂŒscher Daniel
- BĂŒscher Volker
- C-Q Changqiao
- Cabrera UrbĂĄn Susana
- Caforio Davide
- Cai Huacheng
- Cairo Valentina
- Cakir Orhan
- Calace Noemi
- Calafiura Paolo
- Calandri Alessandro
- Calderini Giovanni
- Calfayan Philippe
- Callea Giuseppe
- Caloba Luiz
- Calvente Lopez Sergio
- Calvet David
- Calvet Samuel
- Calvet Thomas
- Camacho Toro Reina
- Camarda Stefano
- Camarri Paolo
- Cameron David
- Caminal Armadans Roger
- Camincher Clement
- Campana Simone
- Campanelli Mario
- Camplani Alessandra
- Campoverde Angel
- Canale Vincenzo
- Cano Bret Marc
- Cantero Josu
- Cao Tingting
- Capeans Garrido Maria
- Caprini Irinel
- Caprini Mihai
- Capua Marcella
- Carbone Ryne
- Cardarelli Roberto
- Cardillo Fabio
- Carli Ina
- Carli Tancredi
- Carlino Gianpaolo
- Carlson Benjamin
- Carminati Leonardo
- Carney Rebecca
- Caron Sascha
- Carquin Edson
- Carrillo-Montoya German
- CarrĂĄ Sonia
- Casadei Diego
- Casado Maria
- Casha Albert
- Casolino Mirkoantonio
- Casper David
- Castelijn Remco
- Castillo Gimenez Victoria
- Castro Nuno
- Catinaccio Andrea
- Catmore James
- Cattai Ariella
- Caudron Julien
- Cavaliere Viviana
- Cavallaro Emanuele
- Cavalli Donatella
- Cavalli-Sforza Matteo
- Cavasinni Vincenzo
- Celebi Emre
- Ceradini Filippo
- Cerda Alberich Leonor
- Cerri Alessandro
- Cerrito Lucio
- Cerutti Fabio
- Cervelli Alberto
- Cetin Serkant
- Chafaq Aziz
- Chakraborty Dhiman
- Chan Stephen
- Chan Wing
- Chan Yat
- Chang Philip
- Chapman John
- Charlton Dave
- Chau Chav
- Chavez Barajas Carlos
- Che Siinn
- Cheatham Susan
- Chegwidden Andrew
- Chekanov Sergei
- Chekulaev Sergey
- Chelkov Gueorgui
- Chelstowska Magda
- Chen Cheng
- Chen Chunhui
- Chen Hucheng
- Chen Jing
- Chen Shenjian
- Chen Shion
- Chen Xin
- Chen Ye
- Cheng Hok
- Cheng Huajie
- Cheplakov Alexander
- Cheremushkina Evgeniya
- Cherkaoui El Moursli Rajaa
- Cheu Elliott
- Cheung Kingman
- Chevalier Laurent
- Chiarella Vitaliano
- Chiarelli Giorgio
- Chiodini Gabriele
- Chisholm Andrew
- Chitan Adrian
- Chiu Yu
- Chizhov Mihail
- Choi Kyungeon
- Chomont Arthur
- Chouridou Sofia
- Chow Yun
- Christodoulou Valentinos
- Chu Ming
- Chudoba Jiri
- Chuinard Annabelle
- Chwastowski Janusz
- Chytka Ladislav
- Ciftci Abbas
- Cinca Diane
- Cindro Vladimir
- Cioara Irina
- Ciocio Alessandra
- Cirotto Francesco
- Citron Zvi
- Citterio Mauro
- Ciubancan Mihai
- Clark Allan
- Clark Brian
- Clark Michael
- Clark Philip
- Clarke Robert
- Clement Christophe
- Coadou Yann
- Cobal Marina
- Coccaro Andrea
- Cochran James
- Colasurdo Luca
- Cole Brian
- Colijn Auke-Pieter
- Collot Johann
- Colombo Tommaso
- Conde Muiño Patricia
- Coniavitis Elias
- Connell Simon
- Connelly Ian
- Constantinescu Serban
- Conti Geraldine
- Conventi Francesco
- Cooke Mark
- Cooper-Sarkar Amanda
- Cormier Felix
- Cormier Kyle
- Corradi Massimo
- Corriveau Francois
- Cortes-Gonzalez Arely
- Costa Giuseppe
- Costa MarĂa
- Costanzo Davide
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- Glaysher Paul
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- Godlewski Jan
- Goldfarb Steven
- Golling Tobias
- Golubkov Dmitry
- Gomes Agostinho
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- Goncalves Pinto Firmino Da Costa Joao
- Gonella Giulia
- Gonella Laura
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- Gonnella Francesco
- Gonski Julia
- Gonzalez-Sevilla Sergio
- GonzĂĄlez de la Hoz Santiago
- Gonçalo Ricardo
- Goossens Luc
- Gorbounov Petr
- Gordon Howard
- Gorini Benedetto
- Gorini Edoardo
- GoriĆĄek Andrej
- Goshaw Alfred
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- Goudet Christophe
- Goujdami Driss
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- Govender Nicolin
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- Gradin Per
- Gramling Johanna
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- Gravila Paul
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- Gray Heather
- Greenwood Zeno
- Grefe Christian
- Gregersen Kristian
- Gregor Ingrid-Maria
- Grenier Philippe
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- Griffiths Justin
- Grillo Alexander
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- Gris Philippe
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- Groh Sabrina
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- Guo Jun
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- Gutelman Benjamin
- Gutierrez Ortiz Nicolas
- Gutierrez Phillip
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- Gwenlan Claire
- Gwilliam Carl
- Gössling Claus
- Haas Andy
- Haber Carl
- Hadavand Haleh
- Haddad Nacim
- Hadef Asma
- Hageböck Stephan
- Hagihara Mutsuto
- Hakobyan Hrachya
- Haleem Mahsana
- Haley Joseph
- Halladjian Garabed
- Hallewell Gregory
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- Hamal Petr
- Hamano Kenji
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- Hamity Guillermo
- Hamnett Phillip
- Han Liang
- Han Shuo
- Hanagaki Kazunori
- Hanawa Keita
- Hance Michael
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- Hawkings Richard
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- Heelan Louise
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- Hill John
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- Hobbs John
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- Hoeferkamp Martin
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- Honda Takuya
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- Hooberman Benjamin
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- Hostachy Jean-Yves
- Hostiuc Alexandru
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- Hoummada Abdeslam
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- Hoya Joaquin
- Hrabovsky Miroslav
- Hrdinka Julia
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- Iturbe Ponce Julia
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- Kay Ellis
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- Keyes Robert
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- Khanov Alexander
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- Kobayashi Aine
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- Korolkov Ilya
- Korolkova Elena
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- Kourkoumeli-Charalampidi Athina
- Kourkoumelis Christine
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- Kowalewski Robert
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- Kozanecki Witold
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- Langenberg Robert
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- Lantzsch Kerstin
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- LAPLACE Sandrine
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- Lasagni Manghi Federico
- Lassnig Mario
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- Lee Claire
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- Lefebvre Benoit
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- Lefebvre Michel
- Legger Federica
- Leggett Charles
- Lehmann Miotto Giovanna
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- Sugaya Yorihito
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- Sultan D
- Sultansoy Saleh
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- Taylor Aaron
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- Taylor Pierre
- Taylor Wendy
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- Teng Ping-Kun
- Teoh Jia
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- Terada Susumu
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- Terron Juan
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- Teuscher Richard
- Thais Savannah
- Theveneaux-Pelzer Timothée
- Thiele Fabian
- Thomas Juergen
- Thomas-Wilsker Joshuha
- Thompson Paul
- Thompson Stan
- Thomsen Lotte
- Thomson Evelyn
- Tian Yun
- Tibbetts Mark
- Ticse Torres Royer
- Tikhomirov Vladimir
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- Tipton Paul
- Tisserant Sylvain
- Todome Kazuki
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- Tolley Emma
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- Tresoldi Fabio
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- Trigger Isabel
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- Trischuk William
- Trocmé Benjamin
- Trofymov Artur
- Troncon Clara
- Trottier-McDonald Michel
- Trovatelli Monica
- Truong Loan
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- Trzupek Adam
- Tsang Ka
- Tseng Jeffrey
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- Tsirintanis Nikolaos
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- Tuna Alexander
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- Valéry Lo\"ic
- Van Den Wollenberg Wouter
- van der Graaf Harry
- van Gemmeren Peter
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- van Vulpen Ivo
- van Woerden Marius
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- Vasquez Gerardo
- Vasquez Jared
- Vazeille Francois
- Vazquez Furelos David
- Vazquez Schroeder Tamara
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- Yamatani Masahiro
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- Zemaityte Gabija
- Zemla Andrzej
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- Zhang Dengfeng
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- Zhang Huijun
- Zhang Jinlong
- Zhang Lei
- Zhang Liqing
- Zhang Matt
- Zhang Peng
- Zhang Rui
- Zhang Ruiqi
- Zhang Xueyao
- Zhang Yu
- Zhang Zhiqing
- Zhao Xiandong
- Zhao Yongke
- Zhao Zhengguo
- Zhemchugov Alexey
- Zhou Bing
- Zhou Chen
- Zhou Li
- Zhou Maosen
- Zhou Mingliang
- Zhou Ning
- Zhou You
- Zhu Cheng
- Zhu Hongbo
- Zhu Junjie
- Zhu Yingchun
- Zhuang Xuai
- Zhukov Konstantin
- Zibell Andre
- Zieminska Daria
- Zimine Nikolai
- Zimmermann Christoph
- Zimmermann Stephanie
- Zinonos Zinonas
- Zinser Markus
- Ziolkowski Michael
- Zobernig Georg
- Zoccoli Antonio
- Zou Rui
- zur Nedden Martin
- Zwalinski Lukasz
- Ă kesson Torsten
- Ć filigoj Tina
- ĆœeniĆĄ Tibor
- ĆœivkoviÄ Lidija
- Îlvarez Piqueras DamiĂĄn
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2017
- Field of study
A search for weakly interacting massive particle dark matter produced in association with bottom or top quarks is presented. Final states containing third-generation quarks and miss- ing transverse momentum are considered. The analysis uses 36.1 fbâ1 of protonâproton collision data recorded by the ATLAS experiment at âs = 13 TeV in 2015 and 2016. No significant excess of events above the estimated backgrounds is observed. The results are in- terpreted in the framework of simplified models of spin-0 dark-matter mediators. For colour- neutral spin-0 mediators produced in association with top quarks and decaying into a pair of dark-matter particles, mediator masses below 50 GeV are excluded assuming a dark-matter candidate mass of 1 GeV and unitary couplings. For scalar and pseudoscalar mediators produced in association with bottom quarks, the search sets limits on the production cross- section of 300 times the predicted rate for mediators with masses between 10 and 50 GeV and assuming a dark-matter mass of 1 GeV and unitary coupling. Constraints on colour- charged scalar simplified models are also presented. Assuming a dark-matter particle mass of 35 GeV, mediator particles with mass below 1.1 TeV are excluded for couplings yielding a dark-matter relic density consistent with measurements
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.
- Author
- A Aouacheria
- A Aouacheria
- A Aranovich
- A Ashkenazi
- A Ashkenazi
- A Ashkenazi
- A Bernet
- A Buque
- A Chiche
- A Conte
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- A Crockford
- A Degterev
- A Degterev
- A Dey
- A Gast
- A Gross
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- A Kamb
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- A Kotschy
- A Letai
- A Linkermann
- A Linkermann
- A Linkermann
- A Linkermann
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- A Nilsson
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- A Seiler
- A Serrano-Puebla
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- A Strasser
- A Strasser
- A Strasser
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- A Strasser
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- A Sundararaman
- A Tittarelli
- A Trautmann
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- A Zychlinsky
- AA Fatokun
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- AB Pardee
- Abhishek D. Garg
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- Vincenzo De Laurenzi
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- Y Aachoui
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- Y Dondelinger
- Y Dondelinger
- Y Dondelinger
- Y Dondelinger
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- Y Fuchs
- Y Fuchs
- Y Ishizaki
- Y Ito
- Y Lee
- Y Li
- Y Li
- Y Liu
- Y Liu
- Y Luo
- Y Ma
- Y Ma
- Y Morizane
- Y Ou
- Y Pang
- Y Rong
- Y Shlyakhtina
- Y Subburaj
- Y Suzuki
- Y Tsujimoto
- Y Wang
- Y Wang
- Y Wang
- Y Wang
- Y Xie
- Y Xie
- Y Xie
- Y Zaltsman
- Y Zermati
- Y Zhang
- Y Zheng
- Y Zhu
- Y Zhu
- YB Chen
- YC Hou
- YH Liao
- YI Nakajima
- Ying Wang
- YN Gong
- Yoshihide Tsujimoto
- YS Cho
- Yufang Shi
- Z Cai
- Z Cai
- Z Wang
- Z Wang
- Z Xu
- Z You
- Z Zhang
- Z Zhong
- Zahra Zakeri
- ZG Liu
- ZN Oltvai
- ZT Schafer
- ZX Chen
- ZX Chen
- Publication venue
- Cell Death Differ
- Publication date
- 01/01/2018
- Field of study
Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated guidelines for the definition and interpretation of cell death from morphological, biochemical, and functional perspectives. Since the field continues to expand and novel mechanisms that orchestrate multiple cell death pathways are unveiled, we propose an updated classification of cell death subroutines focusing on mechanistic and essential (as opposed to correlative and dispensable) aspects of the process. As we provide molecularly oriented definitions of terms including intrinsic apoptosis, extrinsic apoptosis, mitochondrial permeability transition (MPT)-driven necrosis, necroptosis, ferroptosis, pyroptosis, parthanatos, entotic cell death, NETotic cell death, lysosome-dependent cell death, autophagy-dependent cell death, immunogenic cell death, cellular senescence, and mitotic catastrophe, we discuss the utility of neologisms that refer to highly specialized instances of these processes. The mission of the NCCD is to provide a widely accepted nomenclature on cell death in support of the continued development of the field
Measurement of the ttÂŻttÂŻ production cross section in pp collisions at âs=13 TeV with the ATLAS detector
- Author
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- Zhemchugov A
- Zheng Z
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- Zhukov K
- Zhulanov V
- Zieminska D
- Zimine NI
- Zimmermann S
- Ziolkowski M
- Zoccoli A
- Zoch K
- Zorbas TG
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- Ă kesson TPA
- Ăncel ĂO
- ĆœeniĆĄ T
- ĆœivkoviÄ L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 16/11/2021
- Field of study
A measurement of four-top-quark production using proton-proton collision data at a centre-of-mass energy of 13 TeV collected by the ATLAS detector at the Large Hadron Collider corresponding to an integrated luminosity of 139 fbâ1 is presented. Events are selected if they contain a single lepton (electron or muon) or an opposite-sign lepton pair, in association with multiple jets. The events are categorised according to the number of jets and how likely these are to contain b-hadrons. A multivariate technique is then used to discriminate between signal and background events. The measured four-top-quark production cross section is found to be 26+17â15 fb, with a corresponding observed (expected) significance of 1.9 (1.0) standard deviations over the background-only hypothesis. The result is combined with the previous measurement performed by the ATLAS Collaboration in the multilepton final state. The combined four-top-quark production cross section is measured to be 24+7â6 fb, with a corresponding observed (expected) signal significance of 4.7 (2.6) standard deviations over the background-only predictions. It is consistent within 2.0 standard deviations with the Standard Model expectation of 12.0 ± 2.4 fb
Measurements of W+Wâ+ â„ 1 jet production cross-sections in pp collisions at sâ = 13 TeV with the ATLAS detector
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- Zahreddine J
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- Zanzi D
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- ZeiĂner SV
- Zemaityte G
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- Zenin O
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- Zhang B
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- Zhemchugov A
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- Ă kesson TPA
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/06/2021
- Field of study
Fiducial and differential cross-section measurements of W+Wâ production in
association with at least one hadronic jet are presented. These measurements are sensitive
to the properties of electroweak-boson self-interactions and provide a test of perturbative
quantum chromodynamics and the electroweak theory. The analysis is performed using
proton-proton collision data collected at p
s = 13TeV with the ATLAS experiment, corresponding
to an integrated luminosity of 139 fbâ1. Events are selected with exactly one oppositely
charged electron-muon pair and at least one hadronic jet with a transverse momentum
of pT > 30 GeV and a pseudorapidity of |ïżœ| < 4.5. After subtracting the background
contributions and correcting for detector effects, the jet-inclusive W+Wâ+ ïżœ 1 jet fiducial
cross-section and W+Wâ+ jets differential cross-sections with respect to several kinematic
variables are measured. These measurements include leptonic quantities, such as the lepton
transverse momenta and the transverse mass of the W+Wâ system, as well as jet-related
observables such as the leading jet transverse momentum and the jet multiplicity. Limits on
anomalous triple-gauge-boson couplings are obtained in a phase space where interference
between the Standard Model amplitude and the anomalous amplitude is enhanced
- âŠ