Increasing New Orienting Emergency Department Nurses\u27 Awareness of Mass Casualty Incident Emergency Preparedness and Disaster Response Core Competencies to Improve Mass Casualty Incident Response

Mass casualty incidents (MCI) impose a substantial threat to healthcare. Despite the increasing frequency of MCIs many healthcare organizations and nursing programs do not adequately prepare nurses to be effective responders during an MCI. This evidence-based practice pilot project was purposed to increase new orienting emergency department nurses’ confidence and ability to effectively respond to an MCI. This project involved implementing an MCI educational program consisting of a disaster nursing framework to educate new orienting emergency department nurses on emergency preparedness and disaster response core competencies. The project leader utilized a quasi-experimental design to collect data pre- and post-intervention utilizing a modified Emergency Preparedness Information Questionnaire (EPIQ). The measurable outcomes for the project included improvement in awareness of competencies relate to MCI emergency preparedness, awareness of competencies related to disaster response, and level of self-reported confidence to respond to MCIs. This project revealed a statistically significant improvement in the awareness of emergency preparedness and disaster response core competencies among new orienting emergency department nurses as well as enhanced self-reported confidence to respond to an MCI. The results of this project have important implications for enhancing MCI education for nurses to develop prepared and effective responses to MCIs

Search for light resonances decaying to boosted quark pairs and produced in association with a photon or a jet in proton–proton collisions at √s=13 TeV with the ATLAS detector

This Letter presents a search for new light resonances decaying to pairs of quarks and produced in association with a high-pT photon or jet. The dataset consists of proton–proton collisions with an integrated luminosity of 36.1 fb−1at a centre-of-mass energy of √s=13TeV recorded by the ATLAS detector at the Large Hadron Collider. Resonance candidates are identified as massive large-radius jets with substructure consistent with a particle decaying into a quark pair. The mass spectrum of the candidates is examined for local excesses above background. No evidence of a new resonance is observed in the data, which are used to exclude the production of a lepto-phobic axial-vector Z boson

Measurement of the inclusive cross-section for the production of jets in association with a Z boson in proton-proton collisions at 8 TeV using the ATLAS detector

The inclusive cross-section for jet production in association with a Z boson decaying into an electron–positron pair is measured as a function of the transverse momentum and the absolute rapidity of jets using 19.9 fb −1 of s√=8 TeV proton–proton collision data collected with the ATLAS detector at the Large Hadron Collider. The measured Z + jets cross-section is unfolded to the particle level. The cross-section is compared with state-of-the-art Standard Model calculations, including the next-to-leading-order and next-to-next-to-leading-order perturbative QCD calculations, corrected for non-perturbative and QED radiation effects. The results of the measurements cover final-state jets with transverse momenta up to 1 TeV, and show good agreement with fixed-order calculations

Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

Rational design and synthesis of modified teixobactin analogues: in vitro antibacterial activity against Staphylococcus aureus, Propionibacterium acnes and Pseudomonas aeruginosa

Teixobactin, a recently discovered depsipeptide that binds to bacterial lipid II and lipid III, provides a promising molecular scaffold for the design of new antimicrobials. Herein, we describe the synthesis and antimicrobial evaluation of systematically modified teixobactin analogues. The replacement of Ile11 residue with aliphatic isosteres, the modification of the guanidino group at residue 10 and the introduction of a rigidifying residue, dehydroamino acid into the macrocyclic ring generated useful structure‐activity information. Extensive antimicrobial susceptibility assessment against a panel of clinically relevant Staphylococcus aureus and Propionibacterium acnes led to the identification of a new lead compound, [Arg(Me)10,Nle11]teixobactin 63, with excellent bactericidal activity (MIC 2‐4 μg/mL). Significantly, the antimicrobial activity of several of the teixobactin analogues against the pathogenic Gram‐negative Pseudomonas aeruginosa was 'restored' when combined with sub‐MIC concentration of the outer membrane‐disruptive antibiotic, colistin. The antimicrobial effectiveness of [Tfn10,Nle11]teixobactin 66 (32 μg/mL)‐colistin (2 μg/mL; 0.5x MIC) combination against P. aeruginosa PAO1 reveal, for the first time, an alternative therapeutic option in the treatment of Gram‐negative infections

How KANERE Free Press Resists Biopower

How does a free press resist state biopower? This article studies  the development and dissemination of KANERE Free Press, a refugee-run news source operating in the Kakuma Refugee Camp, that was founded to create “a more open society in refugee camps and to develop a platform for fair public debate on refugee affairs” (KANERE Vision Statement). The analysis of KANERE and its impact on the political subjectivity of refugees living in Kakuma is framed by Foucault’s theory of biopower, the state-sanctioned right to “make live or let die” in its management of human populations. The author demonstrates the force relations between KANERE, its host country of Kenya, and the UNHCR through two ongoing stories covered by KANERE: the broad rejection of the MixMe nutritional supplement and the expressed disdain for the camp’s World Refugees Day celebration. Using ethnographic and decolonizing methodologies, the author privileges the voices and perspectives of the KANERE editors and the Kakuma residents they interviewed in order to provide a ground-level view of refugee’s lived experiences in Kakuma. As KANERE records refugees’ experiences of life in the camp, they construct a narrative community that is simultaneously produced by and resistant to the regulations and control of camp administration and state sovereignty. In doing so, KANERE creates a transgressive space that reaches beyond the confines of the camp.Par quels moyens peut une presse libre résister au biopouvoir de l’état ? Cet article se penche sur le développement et la dissémination de la KANERE Free Press, une source d’actualités gérée par les réfugiés qui opère dans le Kakuma Refugee Camp (camp des réfugiés de Kakuma) fondé dans l’intention de créer « une société plus ouverte dans le camp des réfugiés et d’établir un cadre pour un débat public juste et équitable sur les questions concernant les réfugiés » (extrait de l’énoncé de vision KANERE). Cette analyse de la KANERE Free Press et de son impact sur la subjectivité politique des réfugiés installés à Kakuma s’opère dans le contexte de la théorie de Foucault du biopouvoir, le droit détenu par l’état de « faire vivre ou laisser mourir » dans son administration des populations humaines. L’auteur démontre les relations de force qui existent entre KANERE et son état hôte du Kenya, ainsi que le HCR, par l’entremise de deux instances d’actualités en cours qui ont fait l’objet d’un reportage par KANERE : le rejet généralisé du complément alimentaire MixMe et le mépris manifesté à l’égard des fêtes du camp pour la Journée mondiale des réfugiés. En se servant des méthodologies ethnographiques et de décolonisation, l’auteur place au premier plan les voix et perspectives des rédacteurs de KANERE ainsi que les résidents qui ont participé aux entrevues afin de fournir un aperçu intime des expériences vécues des réfugiés à Kakuma. En rapportant les expériences de la vie des réfugiés internés dans le camp, KANERE développe une communauté liée par le récit qui est à la fois le produit des règlements et du système de contrôle de l’administration du camp et de la souveraineté de l’état, et un élément de résistance à cellesci. KANERE crée ainsi un espace transgressif dont la portée s’étend au-delà des limites du camp