268 research outputs found
Using Cepheids to determine the galactic abundance gradient I. The solar neighbourhood
A number of studies of abundance gradients in the galactic disk have been
performed in recent years. The results obtained are rather disparate: from no
detectable gradient to a rather significant slope of about -0.1 dex kpc -1. The
present study concerns the abundance gradient based on the spectroscopic
analysis of a sample of classical Cepheids. These stars enable one to obtain
reliable abundances of a variety of chemical elements. Additionally, they have
well determined distances which allow an accurate determination of abundance
distributions in the galactic disc. Using 236 high resolution spectra of 77
galactic Cepheids, the radial elemental distribution in the galactic disc
between galactocentric distances in the range 6-11 kpc has been investigated.
Gradients for 25 chemical elements (from carbon to gadolinium) are derived...Comment: 28 pages, 14 postscript figures, LaTeX, uses Astronomy and
Astrophysics macro aa.cls, graphicx package, to be published in Astronomy and
Astrophysics (2002) also available at
http://www.iagusp.usp.br/~maciel/index.htm
Both unmedicated and medicated individuals with schizophrenia show impairments across a wide array of cognitive and reinforcement learning tasks
BACKGROUND: Schizophrenia is a disorder characterized by pervasive deficits in cognitive functioning. However, few well-powered studies have examined the degree to which cognitive performance is impaired even among individuals with schizophrenia not currently on antipsychotic medications using a wide range of cognitive and reinforcement learning measures derived from cognitive neuroscience. Such research is particularly needed in the domain of reinforcement learning, given the central role of dopamine in reinforcement learning, and the potential impact of antipsychotic medications on dopamine function.
METHODS: The present study sought to fill this gap by examining healthy controls (N = 75), unmedicated (N = 48) and medicated (N = 148) individuals with schizophrenia. Participants were recruited across five sites as part of the CNTRaCS Consortium to complete tasks assessing processing speed, cognitive control, working memory, verbal learning, relational encoding and retrieval, visual integration and reinforcement learning.
RESULTS: Individuals with schizophrenia who were not taking antipsychotic medications, as well as those taking antipsychotic medications, showed pervasive deficits across cognitive domains including reinforcement learning, processing speed, cognitive control, working memory, verbal learning and relational encoding and retrieval. Further, we found that chlorpromazine equivalency rates were significantly related to processing speed and working memory, while there were no significant relationships between anticholinergic load and performance on other tasks.
CONCLUSIONS: These findings add to a body of literature suggesting that cognitive deficits are an enduring aspect of schizophrenia, present in those off antipsychotic medications as well as those taking antipsychotic medications
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Managing EEG studies: How to prepare and what to do once data collection has begun
In this paper, we provide guidance for the organization and implementation of EEG studies. This work was inspired by our experience conducting a large-scale, multi-site study, but many elements could be applied to any EEG project. Section 1 focuses on study activities that take place before data collection begins. Topics covered include: establishing and training study teams, considerations for task design and piloting, setting up equipment and software, development of formal protocol documents, and planning communication strategy with all study team members. Section 2 focuses on what to do once data collection has already begun. Topics covered include: (1) how to effectively monitor and maintain EEG data quality, (2) how to ensure consistent implementation of experimental protocols, and (3) how to develop rigorous preprocessing procedures that are feasible for use in a large-scale study. Links to resources are also provided, including sample protocols, sample equipment and software tracking forms, sample code, and tutorial videos (to access resources, please visit: https://osf.io/wdrj3/)
Correlation between technetium and lithium in a sample of oxygen-rich AGB variables
The aims of this paper are: 1) to revisit the Tc content of a sample of
oxygen-rich asymptotic giant branch (AGB) variables and 2) to increase the
number of such stars for which the Li abundance has been measured to provide
constraints on theoretical models of extra-mixing processes. To this end, we
analysed high-resolution spectra of 18 sample stars for the presence of
absorption lines of Tc and Li. The abundance of the latter was determined by
comparing the observed spectra to hydrostatic MARCS model spectra. Bolometric
magnitudes were established from near-IR photometry and pulsation periods. We
reclassify the star V441 Cyg as Tc-rich, and the unusual Mira star R Hya, as
well as W Eri, as Tc-poor. The abundance of Li, or an upper limit to it, was
determined for all of the sample stars. In all stars with Tc we also detected
Li. Most of them have a Li content slightly below the solar photospheric value,
except for V441 Cyg, which has ~1000 times the solar abundance. We also found
that, similar to Tc, a lower luminosity limit seems to exist for the presence
of Li. We conclude that the higher Li abundance found in the cooler and higher
luminosity objects could stem from a Li production mechanism operating on the
AGB. The stellar mass might have a crucial influence on this (extra-mixing)
production mechanism. It was speculated that the declining pulsation period of
R Hya is caused by a recent thermal pulse (TP). While not detecting Tc does not
rule out a TP, it indicates that the TPs are not strong enough to drive
dredge-up in R Hya. V441 Cyg, on the other hand, could either be a low-mass,
intrinsic S-star that produced its large amount of Li by extra-mixing
processes, or an intermediate-mass star (M>=M_sun) undergoing Li production due
to hot bottom burning.Comment: 12 pages, 7 figures, accepted for publication in A&
Direct detection of a magnetic field in the photosphere of the single M giant EK Boo: How common is magnetic activity among M giants?
We study the fast rotating M5 giant EK Boo by means of spectropolarimetry to
obtain direct and simultaneous measurements of both the magnetic field and
activity indicators, in order to infer the origin of the activity in this
fairly evolved giant. We used the new spectropolarimeter NARVAL at the Bernard
Lyot Telescope (Observatoire du Pic du Midi, France) to obtain a series of
Stokes I and Stokes V profiles for EK Boo. Using the Least Square Deconvolution
technique we were able to detect the Zeeman signature of the magnetic field. We
measured its longitudinal component by means of the averaged Stokes V and
Stokes I profiles. The spectra also permitted us to monitor the CaII K&H
chromospheric emission lines, which are well known as indicators of stellar
magnetic activity. From ten observations obtained between April 2008 and March
2009, we deduce that EK Boo has a magnetic field, which varied in the range of
-0.1 to -8 G. We also determined the initial mass and evolutionary stage of EK
Boo, based on up-to-date stellar evolution tracks. The initial mass is in the
range of 2.0-3.6 M_sun, and EK Boo is either on the asymptotic giant branch
(AGB), at the onset of the thermal pulse phase, or at the tip of the first (or
red) giant branch (RGB). The fast rotation and activity of EK Boo might be
explained by angular momentum dredge-up from the interior, or by the merging of
a binary. In addition, we observed eight other M giants, which are known as
X-ray emitters, or to be rotating fast for their class. For one of these, beta
And, presumably also an AGB star, we have a marginal detection of magnetic
field, and a longitudinal component Bl of about 1G was measured. More
observations like this will answer the question whether EK Boo is a special
case, or whether magnetic activity is, rather, more common among M giants than
expected.Comment: Accepted for publication in Astronomy & Astrophysics, 10 pages, 8
figure
Emotional cues enhance the attentional effects on spatial and temporal resolution
In the present study, we demonstrated that the emotional significance of a spatial cue enhances the effect of covert attention on spatial and temporal resolution (i.e., our ability to discriminate small spatial details and fast temporal flicker). Our results indicated that fearful face cues, as compared with neutral face cues, enhanced the attentional benefits in spatial resolution but also enhanced the attentional deficits in temporal resolution. Furthermore, we observed that the overall magnitudes of individuals’ attentional effects correlated strongly with the magnitude of the emotion × attention interaction effect. Combined, these findings provide strong support for the idea that emotion enhances the strength of a cue’s attentional response
A homogeneous spectroscopic analysis of host stars of transiting planets
The analysis of transiting extra-solar planets provides an enormous amount of
information about the formation and evolution of planetary systems. A precise
knowledge of the host stars is necessary to derive the planetary properties
accurately. The properties of the host stars, especially their chemical
composition, are also of interest in their own right. Information about planet
formation is inferred by, among others, correlations between different
parameters such as the orbital period and the metallicity of the host stars.
The stellar properties studied should be derived as homogeneously as possible.
The present work provides new, uniformly derived parameters for 13 host stars
of transiting planets. Effective temperature, surface gravity, microturbulence
parameter, and iron abundance were derived from spectra of both high
signal-to-noise ratio and high resolution by assuming iron excitation and
ionization equilibria. For some stars, the new parameters differ from previous
determinations, which is indicative of changes in the planetary radii. A
systematic offset in the abundance scale with respect to previous assessments
is found for the TrES and HAT objects. Our abundance measurements are
remarkably robust in terms of the uncertainties in surface gravities. The iron
abundances measured in the present work are supplemented by all previous
determinations using the same analysis technique. The distribution of iron
abundance then agrees well with the known metal-rich distribution of planet
host stars. To facilitate future studies, the spectroscopic results of the
current work are supplemented by the findings for other host stars of
transiting planets, for a total dataset of 50 objects.Comment: accepted for publication in A&A, 7 pages, 6 figure
Differences in social decision-making between proposers and responders during the ultimatum game: an eeg study
The Ultimatum Game (UG) is a typical paradigm to investigate social decision-making. Although the behavior of humans in this task is already well established, the underlying brain processes remain poorly understood. Previous investigations using event-related potentials (ERPs) revealed three major components related to cognitive processes in participants engaged in the responder condition, the early ERP component P2, the feedback-related negativity (FRN) and a late positive wave (late positive component, LPC). However, the comparison of the ERP waveforms between the responder and proposer conditions has never been studied. Therefore, to investigate condition-related electrophysiological changes, we applied the UG paradigm and compared parameters of the P2, LPC and FRN components in twenty healthy participants. For the responder condition, we found a significantly decreased amplitude and delayed latency for the P2 component, whereas the mean amplitudes of the LPC and FRN increased compared to the proposer condition. Additionally, the proposer condition elicited an early component consisting of a negative deflection around 190 ms, in the upward slope of the P2, probably as a result of early conflict-related processing. Using independent component analysis (ICA), we extracted one functional component time-locked to this deflection, and with source reconstruction (LAURA) we found the anterior cingulate cortex (ACC) as one of the underlying sources. Overall, our findings indicate that intensity and time-course of neuronal systems engaged in the decision-making processes diverge between both UG conditions, suggesting differential cognitive processes. Understanding the electrophysiological bases of decision-making and social interactions in controls could be useful to further detect which steps are impaired in psychiatric patients in their ability to attribute mental states (such as beliefs, intents, or desires) to oneself and others. This ability is called mentalizing (also known as theory of mind)
Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis
BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London
Novelty Enhances Visual Perception
The effects of novelty on low-level visual perception were investigated in two experiments using a two-alternative forced-choice tilt detection task. A target, consisting of a Gabor patch, was preceded by a cue that was either a novel or a familiar fractal image. Participants had to indicate whether the Gabor stimulus was vertically oriented or slightly tilted. In the first experiment tilt angle was manipulated; in the second contrast of the Gabor patch was varied. In the first, we found that sensitivity was enhanced after a novel compared to a familiar cue, and in the second we found sensitivity to be enhanced for novel cues in later experimental blocks when participants became more and more familiarized with the familiar cue. These effects were not caused by a shift in the response criterion. This shows for the first time that novel stimuli affect low-level characteristics of perception. We suggest that novelty can elicit a transient attentional response, thereby enhancing perception
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