646 research outputs found
The GAA triplet-repeat is unstable in the context of the human FXN locus and displays age-dependent expansions in cerebellum and DRG in a transgenic mouse model
- Author
- A Dürr
- A Filla
- AE Harding
- AJ Jeffreys
- Anna P. Malykhina
- AS Lia
- C Savouret
- CA Thornton
- CJ Miranda
- D Lorenzetti
- DG Monckton
- DG Monckton
- E Monrós
- EN Burright
- H Ikeda
- H Seznec
- Irene De Biase
- JD Brook
- K Manley
- K Ohshima
- K Watase
- L Kennedy
- L Kennedy
- L Mangiarini
- L Martorell
- L Montermini
- L Pianese
- LJ Wong
- LM Pollard
- M Anvret
- M Cossée
- M Gomes-Pereira
- M Gomes-Pereira
- M Gomes-Pereira
- M Mahadevan
- Mark Pook
- MT Fortune
- PM Bingham
- R Sharma
- R Sharma
- Rhonda M. Clark
- S Al-Mahdawi
- Sahar Al-Mahdawi
- Sanjay I. Bidichandani
- SI Bidichandani
- T Ashizawa
- V Campuzano
- VC Wheeler
- WJ Broek van Den
- YH Fu
- YP Goldberg
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 21/09/2006
- Field of study
Friedreich ataxia (FRDA) is caused by homozygosity for FXN alleles containing an expanded GAA triplet-repeat (GAA-TR) sequence. This expanded GAA-TR sequence is unstable in somatic cells of FRDA patients, showing age-dependent expansions in dorsal root ganglia (DRG), the tissue where pathology occurs earliest and is most significant. This is thought to be the basis for the progressive, tissue-specific pathology seen in FRDA, but the mechanism(s) for this somatic instability is unknown. We show that transgenic mice containing the expanded GAA-TR sequence (190 or 82 triplets) in the context of the human FXN locus show tissue-specific and age-dependent somatic instability that mimics the human condition. Small pool PCR analysis, which allows quantitative analysis of instability by assaying individual transgenes in vivo, showed age-dependent expansions specifically in the cerebellum and DRG. The (GAA)190 allele showed some instability by 2 months, progressed at about 0.3 – 0.4 triplets/week, resulting in a significant number of expansions by 12 months. Repeat length determined the age of onset of somatic instability, and the rate and magnitude of expansion. Whereas the GAA-TR was unstable in the context of the human FXN locus, pure GAATR sequences at other genetic loci in the human and murine genomes showed no instability. These data indicate that somatic instability of the GAA-TR sequence in the human FXN gene is determined by a combination of unique cis and trans-acting factors. This mouse model will serve as a useful tool to delineate the mechanism(s) of diseasespecific somatic instability in FRDA
Quantitative measurements of inequality in geographic accessibility to pediatric care in Oita Prefecture, Japan: Standardization with complete spatial randomness
- Author
- A Atkinson
- A Khan
- A Lovett
- A Sen
- AB Atkinson
- AE Joseph
- AP Jones
- B Kennedy
- B Perry
- B Rowlingson
- D Yang
- DC Goodman
- E Bamford
- EK Cromley
- FA Cowell
- GJG Upton
- GM Giorgi
- H Dalton
- H Ding
- H Theil
- HR Waters
- I Kawachi
- J Cinnamon
- J Fortney
- J Hewko
- L Oliver
- L Rosero-Bixby
- LS Costa
- M Guagliardo
- M McGrail
- M McGrail
- M Neteler
- M Ramsbottom-Lucier
- Masayuki Shima
- N Mastuo
- N Schuurman
- R Bivand
- R Carr-Hill
- R Development Core Team
- R Haynes
- R Shahid
- S Clark
- S Kamoshita
- S Teach
- SJ Walsh
- Susumu Tanimura
- T Hakui
- TC Bailey
- TC Ricketts
- W Luo
- W Luo
- Publication venue
- BioMed Central
- Publication date
- 01/01/2011
- Field of study
<p>Abstract</p> <p>Background</p> <p>A quantitative measurement of inequality in geographic accessibility to pediatric care as well as that of mean distance or travel time is very important for priority setting to ensure fair access to pediatric facilities. However, conventional techniques for measuring inequality is inappropriate in geographic settings. Since inequality measures of access distance or travel time is strongly influenced by the background geographic distribution patterns, they cannot be directly used for regional comparisons of geographic accessibility. The objective of this study is to resolve this issue by using a standardization approach.</p> <p>Methods</p> <p>Travel times to the nearest pediatric care were calculated for all children in Oita Prefecture, Japan. Relative mean differences were considered as the inequality measure for secondary medical service areas, and were standardized with an expected value estimated from a Monte Carlo simulation based on complete spatial randomness.</p> <p>Results</p> <p>The observed mean travel times in the area considered averaged 4.50 minutes, ranging from 1.83 to 7.02 minutes. The mean of the observed inequality measure was 1.1, ranging from 0.9 to 1.3. The expected values of the inequality measure varied according to the background geographic distribution pattern of children, which ranged from 0.3 to 0.7. After standardizing the observed inequality measure with the expected one, we found that the ranks of the inequality measure were reversed for the observed areas.</p> <p>Conclusions</p> <p>Using the indicator proposed in this paper, it is possible to compare the inequality in geographic accessibility among regions. Such a comparison may facilitate priority setting in health policy and planning.</p
Search for new phenomena in final states with an energetic jet and large missing transverse momentum in pp collisions at √ s = 8 TeV with the ATLAS detector
- Author
- Aad G
- Abbott B
- Abbott DC
- Abeling K
- Abhayasinghe DK
- Abidi SH
- AbouZeid OS
- Abraham NL
- Abramowicz H
- Abreu H
- Abud AA
- Abulaiti Y
- Acharya BS
- Achkar B
- Adachi S
- Adam L
- Adamczyk L
- Adamek L
- Adelman J
- Adersberger M
- Adiguzel A
- Adorni S
- Adye T
- Affolder AA
- Afik Y
- Agapopoulou C
- Agaras MN
- Aggarwal A
- Agheorghiesei C
- Aguilar-Saavedra JA
- Ahmadov F
- Ahmed WS
- Ai X
- Aielli G
- Akatsuka S
- Akesson TPA
- Akilli E
- Akimov A
- Al Khoury K
- Alberghi GL
- Albert J
- Alderweireldt S
- Aleksa M
- Aleksandrov IN
- Alexa C
- Alexopoulos T
- Alfonsi A
- Alfonsi F
- Alhroob M
- Ali B
- Aliev M
- Alimonti G
- Allaire C
- Allbrooke BMM
- Allen BW
- Allport PP
- Aloisio A
- Alonso F
- Alpigiani C
- Alshehri AA
- Alvarez Estevez M
- Alviggi MG
- Amaral Coutinho Y
- Ambler A
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- Amelung C
- Amidei D
- Amor Dos Santos SP
- Amoroso S
- Amrouche CS
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- Anulli F
- Aoki M
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- Zhemchugov A
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- Zu Theenhausen HM
- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2015
- Field of study
Results of a search for new phenomena in final states with an energetic jet and large missing transverse momentum are reported. The search uses 20.3 fb−1 of √ s = 8 TeV data collected in 2012 with the ATLAS detector at the LHC. Events are required to have at least one jet with pT > 120 GeV and no leptons. Nine signal regions are considered with increasing missing transverse momentum requirements between Emiss T > 150 GeV and Emiss T > 700 GeV. Good agreement is observed between the number of events in data and Standard Model expectations. The results are translated into exclusion limits on models with either large extra spatial dimensions, pair production of weakly interacting dark matter candidates, or production of very light gravitinos in a gauge-mediated supersymmetric model. In addition, limits on the production of an invisibly decaying Higgs-like boson leading to similar topologies in the final state are presente
Jet energy measurement with the ATLAS detector in proton-proton collisions at root s=7 TeV
- Author
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- Collaboration ATLAS
- Collard C
- Collins NJ
- Collins-Tooth C
- Collot J
- Colon G
- Coniavitis E
- Conidi MC
- Consonni M
- Consorti V
- Constantinescu S
- Conta C
- Conventi F
- Cook J
- Cooke M
- Cooper BD
- Cooper-Sarkar AM
- Copic K
- Cornelissen T
- Corradi M
- Correia AMH
- Corriveau F
- Corso-Radu A
- Cortes-Gonzalez A
- Cortiana G
- Costa G
- Costa MJ
- Costanzo D
- Costin T
- Cote D
- Courneyea L
- Cowan G
- Cowden C
- Cox BE
- Cranmer K
- Cranshaw J
- Crepe-Renaudin S
- Crescioli F
- Cristinziani M
- Crosetti G
- Crupi R
- Cuciuc C-M
- Curatolo M
- Curtis CJ
- Curull XE
- Cwetanski P
- Czirr H
- Czyczula Z
- D'Auria S
- D'Onofrio M
- D'Orazio A
- Da Costa JBG
- Da Costa JGPF
- Da Silva PVM
- Da Via C
- Dabrowski W
- Dai T
- Dallapiccola C
- Daly CH
- Dam M
- Damazio DO
- Dameri M
- Damiani DS
- Danielsson HO
- Dannheim D
- Dao V
- Darbo G
- Darlea GL
- Daum C
- Dauvergne JP
- Davey W
- Davidek T
- Davidson N
- Davidson R
- Davies E
- Davies M
- Davison AR
- Davygora Y
- Dawe E
- Dawson I
- Dawson JW
- Daya-Ishmukhametova RK
- de Asmundis R
- De Castro S
- De Cecco S
- De Graat J
- De Groot N
- De Jong P
- De la Hoz SG
- De la Taille C
- De la Torre H
- De Lima JGR
- De Lotto B
- De Mora L
- De Nooij L
- De Pedis D
- De Regie JBDV
- De Renstrom PAB
- De Salvo A
- De Sanctis U
- De Santo A
- De K
- Dean S
- Debbe R
- Dedovich DV
- Degenhardt J
- Dehchar M
- Del Papa C
- Del Peso J
- Del Prete T
- Deliyergiyev M
- Dell'Acqua A
- Dell'Asta L
- Della Pietra M
- Della Porta GZ
- della Volpe D
- Delmastro M
- Delpierre P
- Delruelle N
- Delsart PA
- Deluca C
- Demers S
- Demichev M
- Demirkoz B
- Deng J
- Deng W
- Denis RDS
- Denisov SP
- Derendarz D
- Derkaoui JE
- Derue F
- Dervan P
- Desch K
- Devetak E
- Deviveiros PO
- Dewhurst A
- DeWilde B
- Dhaliwal S
- Dhullipudi R
- Di Ciaccio A
- Di Ciaccio L
- Di Girolamo A
- Di Girolamo B
- Di Luise S
- Di Mattia A
- Di Micco B
- Di Nardo R
- Di Simone A
- Di Sipio R
- Diaz MA
- Diblen F
- Diehl EB
- Dietrich J
- Dietzscha TA
- Diglio S
- Dingfelder J
- Dionisi C
- Dita P
- Dita S
- Dittus F
- Djama F
- Djobava T
- do Vale MAB
- Do ValleWemans A
- Doan TKO
- Dobbs M
- Dobinson R
- Dobos D
- Dobson E
- Dobson M
- Dodd J
- Doglioni C
- Doherty T
- Dohmae T
- Doi Y
- Dolejsi J
- Dolenc I
- Dolezal Z
- Dolgoshein BA
- Donadelli M
- Donega M
- Donini J
- Donszelmann TC
- Dopke J
- Doria A
- Dos Anjos A
- Dos Santos DR
- Dosil M
- Dotti A
- Dova MT
- Dowell JD
- Doxiadis AD
- Doyle AT
- Drasal Z
- Drees J
- Dressnandt N
- Drevermann H
- Driouichi C
- Dris M
- Dubbert J
- Dubbs T
- Dube S
- Duchovni E
- Duckeck G
- Dudarev A
- Dudziak F
- Duehrssen M
- Duerdoth IP
- Dueren M
- Duflot L
- Dufour M-A
- Dunford M
- Duxfield R
- Dwuznik M
- Dydak F
- Ebenstein WL
- Ebke J
- Eckert S
- Eckweiler S
- Edmonds K
- Edwards CA
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- Ehrenfeld W
- Ehrich T
- Eifert T
- Eigen G
- Einsweiler K
- Eisenhandler E
- Ekelof T
- El Kacimi M
- El Moursli RC
- Ellert M
- Elles S
- Ellinghaus F
- Ellis K
- Ellis N
- Elmsheuser J
- Elsing M
- Emeliyanov D
- Engelmann R
- Engl A
- Epp B
- Eppig A
- Erdmann J
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- Ernst J
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- Ernwein J
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- Escalier M
- Eschrich IG
- Escobar C
- Esposito B
- Etienne F
- Etienvre AI
- Etzion E
- Evangelakou D
- Evans H
- Fabbri L
- Fabre C
- Fajardo LSG
- Fakhrutdinov RM
- FalCiano S
- Fang Y
- Fanti M
- Farbin A
- Farilla A
- Farley J
- Farooque T
- Farrington SM
- Farthouat P
- Fassnacht P
- Fassouliotis D
- Fatholahzadeh B
- Favareto A
- Fayard L
- Fazio S
- Febbraro R
- Federic P
- Fedin OL
- Fedorko W
- Fehling-Kaschek M
- Feligioni L
- Fellmann D
- Felzmann CU
- Feng EJ
- Fengd C
- Fenyuk AB
- Ferencei J
- Ferland J
- Fernando W
- Ferrag S
- Ferrando BMS
- Ferrando J
- Ferrara V
- Ferrari A
- Ferrari P
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- Ferrer A
- Ferrer JAV
- Ferrer ML
- Ferrere D
- Ferretti C
- Fiascaris M
- Fiedler F
- Filipcic A
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- Filthaut F
- Fincke-Keeler M
- Fiolhais MCN
- Fiorini L
- Firan A
- Fischer G
- Fischer P
- Fisher MJ
- Fisher SM
- Flechl M
- Fleck I
- Fleckner J
- Fleischmann P
- Fleischmann S
- Flick T
- Flowerdew MJ
- Fokitis M
- Fopma J
- Forbush DA
- Formica A
- Forti A
- Fortin D
- Foster JM
- Fournier D
- Foussat A
- Fowler AJ
- Fowler K
- Fox H
- Francavilla P
- Franchino S
- Francis D
- Frank T
- Franklin M
- Franz S
- Fraternali M
- Fratina S
- Freestone J
- French ST
- Friedrich F
- Froeschl R
- Froidevaux D
- Frost JA
- Fukunaga C
- Fuster J
- Gabaldon C
- Gabizon O
- Gadfort T
- Gadomski S
- Gagliardi G
- Gagnon P
- Galea C
- Gallas EJ
- Gallego EV
- Gallo V
- Gallop BJ
- Gallus P
- Galtieri AB
- Galyaev E
- Gan KK
- Gao YS
- Gapienko VA
- Gaponenko A
- Garberson F
- Garcia BRM
- Garcia C
- Garcia EO
- Garcia YR
- Garcia-Estan MTP
- Garcia-Sciveres M
- Gardner RW
- Garelli N
- Garitaonandia H
- Garonne V
- Garrido MDMC
- Garvey J
- Garzon GOY
- Gatti C
- Gaudio G
- Gaumer O
- Gaur B
- Gauthier L
- Gauzzia P
- Gavrilenko IL
- Gay C
- Gaycken G
- Gayde J-C
- Gazis EN
- Ged P
- Gee CNP
- Geerts DAA
- Geich-Gimbel C
- Gellerstedt K
- Gemme C
- Gemmell A
- Genest MH
- Gentile S
- George M
- George S
- Gerlach P
- Gershon A
- Geweniger C
- Ghazlane H
- Ghodbane N
- Giacobbe B
- Giagu S
- Giakoumopoulou V
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- Gianotti F
- Gibbard B
- Gibson A
- Gibson SM
- Gilbert LM
- Gilchriese M
- Gilewsky V
- Gillberg D
- Gillman AR
- Gimenez VC
- Gingrich DM
- Ginzburg J
- Giokaris N
- Giordani MP
- Giordano R
- Giorgi FM
- Giovannini P
- Giraud PF
- Giugni D
- Giunta M
- Giusti P
- Gjelsten BK
- Gladilin LK
- Glasman C
- Glatzer J
- Glazov A
- Glitza KW
- Glonti GL
- Godfrey J
- Godlewski J
- Goebel M
- Goepfert T
- Goeringer C
- Goessling C
- Goettfert T
- Goia JAM
- Goldfarb S
- Golling T
- Golovnia SN
- Gomes A
- Goncalo R
- Gonella L
- Gonidec A
- Gonzalez S
- Gonzalez-Sevilla S
- Goodson JJ
- Goossens L
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- Gosdzik B
- Gosselink M
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- Goujdami D
- Goulette MP
- Goussiou AG
- Goy C
- Grabowska-Bold I
- Grafstroem P
- Grah C
- Grahn K-J
- Grancagnolo F
- Grancagnolo S
- Grassi V
- Gratchev V
- Grau N
- Gray HM
- Gray JA
- Graziani E
- Grebenyuk OG
- Green B
- Greenfield D
- Greenshaw T
- Greenwood ZD
- Gregersen K
- Gregor IM
- Grenier P
- Griffiths J
- Grigalashvili N
- Grillo AA
- Grinstein S
- Grishkevich YV
- Griso SP
- Grivaz J-F
- Groh M
- Gross E
- Grosse-Knetter J
- Groth-Jensen J
- Grybel K
- Guarino VJ
- Guest D
- Guicheney C
- Guida A
- Guindon S
- Guler H
- Gunther J
- Guo B
- Guo J
- Gupta A
- Gusakov Y
- Gushchin VN
- Gutierrez A
- Gutierrez P
- Guttman N
- Gutzwiller O
- Guyot C
- Gwenlan C
- Gwilliam CB
- Haas A
- Haas S
- Haber C
- Hackenburg R
- Hadavand HK
- Hadley DR
- Haefner P
- Hahn F
- Haider S
- Hajduk Z
- Hakobyan H
- Haller J
- Hamacher K
- Hamal P
- Hamilton A
- Hamilton S
- Han H
- Hanagaki K
- Hanb L
- Hance M
- Handel C
- Hanke P
- Hanninger GN
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- Hansen JD
- Hansen JR
- Hansen PH
- Hansson P
- Hara K
- Hare GA
- Harenberg T
- Harkusha S
- Harpaz SB
- Harper D
- Harrington RD
- Harris OM
- Harrison K
- Hartert J
- Hartjes F
- Haruyama T
- Harvey A
- Hasegawa S
- Hasegawa Y
- Hassani S
- Hatch M
- Hauff D
- Haug S
- Hauschild M
- Hauser R
- Havranek M
- Hawes BM
- Hawkes CM
- Hawkings RJ
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- Hayakawa T
- Hayashi T
- Hayden D
- Hayward HS
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- Hazen E
- He M
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- Hedberg V
- Heelan L
- Heim S
- Heinemann B
- Heisterkamp S
- Helary L
- Heller M
- Hellman S
- Hellmich D
- Helsens C
- Hemperek T
- Henderson RCW
- Henke M
- Henrichs A
- Henrot-Versille S
- Henry-Couannier F
- Hensel C
- Henss T
- Hernandez AMC
- Hernandez CM
- Herrberg R
- Herrera CM
- Hershenhorn AD
- Herten G
- Hertenberger R
- Hervas L
- Hessey NP
- Hidvegi A
- Higon-Rodriguez E
- Hill D
- Hill JC
- Hill N
- Hiller KH
- Hillert S
- Hillier SJ
- Hinchliffe I
- Hines E
- Hirose M
- Hirsch F
- Hirschbuehl D
- Hobbs J
- Hod N
- Hodgkinson MC
- Hodgson P
- Hoecker A
- Hoeferkamp MR
- Hoffman J
- Hoffmann D
- Hohlfeld M
- Holder M
- Holmgren SO
- Holy T
- Holzbauer JL
- Homma Y
- Hong TM
- Horazdovsky T
- Horn C
- Horner S
- Horton K
- Hostachy J-Y
- Hou S
- Houlden MA
- Hoummada A
- Howarth J
- Howell DF
- Hristova I
- Hrivnac J
- Hruska I
- Hryn'ova T
- Hsu PJ
- Hsu S-C
- Huang GS
- Hubacek Z
- Hubaut F
- Huegging F
- Huffman TB
- Hughes EW
- Hughes G
- Hughes-Jones RE
- Huhtinen M
- Hurst P
- Hurwitz M
- Husemann U
- Huseynov N
- Huston J
- Huth J
- Iacobucci G
- Iakovidis G
- Ibbotson M
- Ibragimov I
- Ichimiya R
- Iconomidou-Fayard L
- Idarraga J
- Iengo P
- Igonkina O
- Ikegami Y
- Ikeno M
- Ilchenko Y
- Iliadis D
- Imbault D
- Imori M
- Ince T
- Inigo-Golfin J
- Ioannou P
- Iodice M
- Ishikawa A
- Ishino M
- Ishmukhametov R
- Issever C
- Istin S
- Ivashin AV
- Iwanski W
- Iwasaki H
- Izen JM
- Izzo V
- Jackson B
- Jackson JN
- Jackson P
- Jaekel MR
- Jain V
- Jakobs K
- Jakobsen S
- Jakubek J
- Jana DK
- Jankowski E
- Jansen E
- Jantsch A
- Janus M
- Jarlskog G
- Jeanty L
- Jelen K
- Jenni P
- Jeremie A
- Jez P
- Jezequel S
- Jhaa MK
- Ji H
- Ji W
- Jia J
- Jiangb Y
- Jimenez YH
- Jin G
- Jin S
- Jinnouchi O
- Joergensen MD
- Joffe D
- Johansen LG
- Johansen M
- Johansson KE
- Johansson P
- Johnert S
- Johns KA
- Jon-And K
- Jones G
- Jones RWL
- Jones TJ
- Jones TW
- Jonsson O
- Joram C
- Jorge PM
- Joseph J
- Jovinb T
- Ju X
- Jung CA
- Juranek V
- Jussel P
- Kabachenko VV
- Kabna S
- Kaci M
- Kaczmarska A
- Kadlecik P
- Kado M
- Kagan H
- Kagan M
- Kaiser S
- Kajomovitz E
- Kalinin S
- Kalinovskaya LV
- Kama S
- Kanaya N
- Kaneda M
- Kanno T
- Kantserov VA
- Kanzaki J
- Kaplan B
- Kapliy A
- Kaplon J
- Kar D
- Karagounis M
- Karagoz M
- Karnevskiy M
- Karr K
- Kartvelishvili V
- Karyukhin AN
- Kashif L
- Kasmi A
- Kass RD
- Kastanas A
- Kataoka M
- Kataoka Y
- Katsoufis E
- Katzy J
- Kaushik V
- Kawagoe K
- Kawamoto T
- Kawamura G
- Kayl MS
- Kazanin VA
- Kazarinov MY
- Keates JR
- Keeler R
- Kehoe R
- Keil M
- Kekelidze GD
- Kelly M
- Kennedy J
- Kenney CJ
- Kenyon M
- Kepka O
- Kerschen N
- Kersevan BP
- Kersten S
- Kessoku K
- Ketterer C
- Keung J
- Khakzad M
- Khalil-Zada F
- Khandanyan H
- Khanov A
- Kharchenko D
- Khodinov A
- Kholodenko AG
- Khomich A
- Khoo TJ
- Khoriauli G
- Khoroshilov A
- Khovanskiy N
- Khovanskiy V
- Khramov E
- Khubua J
- Kim H
- Kim MS
- Kim PC
- Kim SH
- Kimura N
- Kind O
- King BT
- King M
- King RSB
- Kirk J
- Kirsch LE
- Kiryunin AE
- Kishimoto T
- Kisielewska D
- Kittelmann T
- Kiver AM
- Kladiva E
- Klaiber-Lodewigs J
- Klein M
- Klein U
- Kleinknecht K
- Klemetti M
- Klier A
- Klimentov A
- Klingenberg R
- Klinkby EB
- Klioutchnikova T
- Klok PF
- Klous S
- Kluge E-E
- Kluge T
- Kluit P
- Kluth S
- Knecht NS
- Kneringer E
- Knobloch J
- Knoops EBFG
- Knue A
- Ko BR
- Kobayashi T
- Kobel M
- Kocian M
- Kocnar A
- Kodys P
- Koeneke K
- Koenig AC
- Koenig S
- Koepke L
- Koetsveld F
- Koevesarki P
- Koffas T
- Koffeman E
- Kohn F
- Kohout Z
- Kohriki T
- Koi T
- Kokott T
- Kolachev GM
- Kolanoski H
- Kolesnikov V
- Koletsoua I
- Koll J
- Kollar D
- Kollefrath M
- Kolya SD
- Komar AA
- Komori Y
- Kondo T
- Kono T
- Kono-Plich R
- Kononov AI
- Konstantinidis N
- Kootz A
- Koperny S
- Kopikov SV
- Korcyl K
- Kordas K
- Koreshev V
- Korn A
- Korol A
- Korolkov I
- Korolkova EV
- Korotkov VA
- Kortner O
- Kortner S
- Kostyukhin VV
- Kotamaki MJ
- Kotov S
- Kotov VM
- Kotwal A
- Kourkoumelis C
- Kouskoura V
- Koutsman A
- Kowalewski R
- Kowalski TZ
- Kozanecki W
- Kozhin AS
- Kral V
- Kramarenko VA
- Kramberger G
- Krasny MW
- Krasznahorkay A
- Kraus J
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- Kreisel A
- Krejci F
- Kretzschmar J
- Krieger N
- Krieger P
- Kroeninger K
- Kroha H
- Kroll J
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- Krstic J
- Kruchonak U
- Kruger H
- Kruker T
- Krumshteyn ZV
- Kruth A
- Kubota T
- Kuehn S
- Kugel A
- Kuhl T
- Kuhn D
- Kukhtin V
- Kulchitsky Y
- Kuleshov S
- Kummer C
- Kuna M
- Kundu N
- Kunkle J
- Kupco A
- Kurashige H
- Kurata M
- Kurochkin YA
- Kus V
- Kuutmann EB
- Kuze M
- Kuzhir P
- Kvita J
- Kwee R
- La Rosa A
- La Rotonda L
- Labarga L
- Labbe J
- Lablak S
- Lacasta C
- Lacava F
- Lacker H
- Lacour D
- Lacuesta VR
- Ladygin E
- Lafaye R
- Laforge B
- Lagouri T
- Lai S
- Laisne E
- Lamanna M
- Lampen CL
- Lampl W
- Lancon E
- Landgraf U
- Landon MPJ
- Landsman H
- Lane JL
- Lange C
- Lankford AJ
- Lanni F
- Lantzsch K
- Lanza A
- Laplace S
- Lapoire C
- Laporte JF
- Lari T
- Larionov AV
- Larner A
- Lasseur C
- Lassnig M
- Latour BMD
- Laurelli P
- Lavrijsen W
- Laycock P
- Lazarev AB
- Le Dortz O
- Le Guirriec E
- Le Maner C
- Le Menedeu E
- Lebel C
- LeCompte T
- Ledroit-Guillon F
- Lee H
- Lee JSH
- Lee L
- Lee SC
- Lefebvre M
- Legendre M
- Leger A
- LeGeyt BC
- Legger F
- Leggett C
- Lehmacher M
- Lei X
- Lei X
- Leite MAL
- Leite MAL
- Leitner R
- Leitner R
- Lellouch D
- Lellouch D
- Leltchouk M
- Leltchouk M
- Lemmer B
- Lemmer B
- Lendermann V
- Leney KJC
- Lenz T
- Lenzen G
- Lenzi B
- Leonhardt K
- Leontsinis S
- Leroy C
- Lessard J-R
- Lesser J
- Lester CG
- Leveque J
- Levin D
- Levinson LJ
- Levitski MS
- Lewandowska M
- Lewis A
- Lewis GH
- Leyko AM
- Leyton M
- Li B
- Li H
- Li S
- Li X
- Liang Z
- Liang Z
- Liao H
- Liberti B
- Lichard P
- Lichtnecker M
- Lie K
- Liebig W
- Lifshitz R
- Lilley JN
- Limbach C
- Limosani A
- Limper M
- Lin SC
- Linde F
- Linnemann JT
- Lipeles E
- Lipinsky L
- Lipniacka A
- Liss TM
- Lissauer D
- Lister A
- Litke AM
- Liu C
- Liu D
- Liu H
- Liu JB
- Liu M
- Liu S
- Liu Y
- Livan M
- Livermore SSA
- Llacer MM
- Lleres A
- Lloyd SL
- Lo Sterzo F
- Lobodzinska E
- Loch P
- Lockman WS
- Loddenkoetter T
- Loebinger FK
- Loginov A
- Loh CW
- Lohse T
- Lohwasser K
- Lokajicek M
- Loken J
- Lombardo VP
- Long RE
- Lopes L
- Losada M
- Loscutoff P
- Losty MJ
- Lou X
- Lounis A
- Loureiro KF
- Love J
- Love PA
- Lowe AJ
- Lu F
- Lubatti HJ
- Luci C
- Lucotte A
- Ludwig A
- Ludwig D
- Ludwig I
- Ludwig J
- Luehring F
- Luijckx G
- Lumb D
- Luminari L
- Lund E
- Lund-Jensen B
- Lundberg B
- Lundberg J
- Lundquist J
- Lungwitz M
- Lupi A
- Lutz G
- Lynn D
- Lys J
- Lytken E
- Ma H
- Ma LL
- Maccarrone G
- Macchiolo A
- Macek B
- Mackeprang R
- Madaras RJ
- Mader WF
- Maenner R
- Maeno T
- Magnoni L
- Magradze E
- Mahalale Y
- Mahboubi K
- Mahout G
- Maiani C
- Maidantchika C
- Maio A
- Majewski S
- Makida Y
- Makovec N
- Mal P
- Malaescu B
- Malecki P
- Malecki P
- Maleev VP
- Malek F
- Mallik U
- Malon D
- Malone C
- Maltezos S
- Malyshev V
- Malyukov S
- Mameghani R
- Mamuzic J
- Manabe A
- Mandelli L
- Mandic I
- Mandrysch R
- Maneira J
- Mangeard PS
- Manjavidze ID
- Mann A
- Manning PM
- Manousakis-Katsikakis A
- Mansoulie B
- Manz A
- Mapelli A
- Mapelli L
- March L
- Marchand JF
- Marchese F
- Marchiori G
- Marcisovsky M
- Marin A
- Marino CP
- Marroquim F
- Marshall R
- Marshall Z
- Martens FK
- Marti-Garcia S
- Martin B
- Martin B
- Martin FF
- Martin JP
- Martin P
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- Yilmaz M
- Yoosootiniya R
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- Zenonos Z
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- Zhemchugov A
- Zheng S
- Zhong J
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- Zhu CG
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- Zhuravlov V
- Zieminska D
- Zimmermann R
- Zimmermann S
- Zimmermann S
- Zinonos Z
- Ziolkowski M
- Zitoun R
- Zivkovic L
- Zmouchko VV
- Zobernig G
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- Zsenei A
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- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/03/2013
- Field of study
The jet energy scale and its systematic uncertainty are determined for jets measured with the ATLAS detector at the LHC in proton-proton collision data at a centre-of-mass energy of √s = 7TeV corresponding to an integrated luminosity of 38 pb-1. Jets are reconstructed with the anti-kt algorithm with distance parameters R=0. 4 or R=0. 6. Jet energy and angle corrections are determined from Monte Carlo simulations to calibrate jets with transverse momenta pT≥20 GeV and pseudorapidities {pipe}η{pipe}<4. 5. The jet energy systematic uncertainty is estimated using the single isolated hadron response measured in situ and in test-beams, exploiting the transverse momentum balance between central and forward jets in events with dijet topologies and studying systematic variations in Monte Carlo simulations. The jet energy uncertainty is less than 2. 5 % in the central calorimeter region ({pipe}η{pipe}<0. 8) for jets with 60≤pT<800 GeV, and is maximally 14 % for pT<30 GeV in the most forward region 3. 2≤{pipe}η{pipe}<4. 5. The jet energy is validated for jet transverse momenta up to 1 TeV to the level of a few percent using several in situ techniques by comparing a well-known reference such as the recoiling photon pT, the sum of the transverse momenta of tracks associated to the jet, or a system of low-pT jets recoiling against a high-pT jet. More sophisticated jet calibration schemes are presented based on calorimeter cell energy density weighting or hadronic properties of jets, aiming for an improved jet energy resolution and a reduced flavour dependence of the jet response. The systematic uncertainty of the jet energy determined from a combination of in situ techniques is consistent with the one derived from single hadron response measurements over a wide kinematic range. The nominal corrections and uncertainties are derived for isolated jets in an inclusive sample of high-pT jets. Special cases such as event topologies with close-by jets, or selections of samples with an enhanced content of jets originating from light quarks, heavy quarks or gluons are also discussed and the corresponding uncertainties are determined. © 2013 CERN for the benefit of the ATLAS collaboration
Measurement of the inclusive and dijet cross-sections of b-jets in pp collisions at sqrt(s) = 7 TeV with the ATLAS detector
- Author
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- Winkelmann S
- Winklmeier F
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- Wolter MW
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- Wosiek BK
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- Woudstra MJ
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- Yanush S
- Yao W-M
- Yao Y
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- Yildiz HD
- Yilmaz M
- Yoosoofmiya R
- Yorita K
- Yoshida R
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- Youssef S
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- Zaitsev AM
- Zajacova Z
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- Zeitnitz C
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- Zemla A
- Zendler C
- Zenin AV
- Zenin O
- Zenis T
- Zenonos Z
- Zenz S
- Zerwas D
- Zhan Z
- Zhang D
- Zhang H
- Zhang J
- Zhang X
- Zhang Z
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- Zhao T
- Zhao Z
- Zhemchugov A
- Zheng S
- Zhong J
- Zhou B
- Zhou N
- Zhou Y
- Zhu CG
- Zhu H
- Zhu Y
- Zhuang X
- Zhuravlov V
- Zieminska D
- Zilka B
- Zimmermann R
- Zimmermann S
- Zimmermann S
- Ziolkowski M
- Zitoun R
- Zivkovic L
- Zmouchko VV
- Zobernig G
- Zoccoli A
- Zolnierowski Y
- Zsenei A
- zur Nedden M
- Zutshi V
- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 31/12/2010
- Field of study
The inclusive and dijet production cross-sections have been measured for jets
containing b-hadrons (b-jets) in proton-proton collisions at a centre-of-mass
energy of sqrt(s) = 7 TeV, using the ATLAS detector at the LHC. The
measurements use data corresponding to an integrated luminosity of 34 pb^-1.
The b-jets are identified using either a lifetime-based method, where secondary
decay vertices of b-hadrons in jets are reconstructed using information from
the tracking detectors, or a muon-based method where the presence of a muon is
used to identify semileptonic decays of b-hadrons inside jets. The inclusive
b-jet cross-section is measured as a function of transverse momentum in the
range 20 < pT < 400 GeV and rapidity in the range |y| < 2.1. The bbbar-dijet
cross-section is measured as a function of the dijet invariant mass in the
range 110 < m_jj < 760 GeV, the azimuthal angle difference between the two jets
and the angular variable chi in two dijet mass regions. The results are
compared with next-to-leading-order QCD predictions. Good agreement is observed
between the measured cross-sections and the predictions obtained using POWHEG +
Pythia. MC@NLO + Herwig shows good agreement with the measured bbbar-dijet
cross-section. However, it does not reproduce the measured inclusive
cross-section well, particularly for central b-jets with large transverse
momenta.Comment: 10 pages plus author list (21 pages total), 8 figures, 1 table, final
version published in European Physical Journal
Childbirth and consequent atopic disease: emerging evidence on epigenetic effects based on the hygiene and EPIIC hypotheses
- Author
- A Petronis
- AB Csoka
- AE Clark
- AI Kendall
- B Jordan
- B Schaub
- C Tolg
- CM Anderson
- CR Cardwell
- DJ Martino
- DP Strachan
- DP Strachan
- DR Fitzpatrick
- E Moshe
- ES Lamouse-Smith
- G White
- GA Rook
- H Cedar
- H Dahlen
- H. G. Dahlen
- H. P. Kennedy
- HG Dahlen
- I Loudon
- ID Neumann
- J Koplin
- J Liu
- J Metsälä
- J Murphy-Lawless
- J Penders
- J Stokholm
- J. Y. Taylor
- JA Mikovits
- JC Madan
- JL Peters
- JR Verani
- K Goto
- L Gibbons
- LCA Rook GA
- M Ehrlich
- M Szyf
- M Wills-Karp
- M. L. Wright
- MF Fraga
- MJ Hyde
- MJ Renfrew
- MM Costantine
- MP Boks
- N Provençal
- NM Miller
- NSW Health
- P Bager
- PA Jones
- PW Laird
- RJ Wright
- S Bomotti
- S Downe
- S Kitzinger
- S Rautava
- S Sreevidya
- S Thavagnanam
- S. Downe
- SL Buchanan
- ST Weiss
- T Olszak
- T Schlinzig
- TA Ajslev
- U Baron
- WJ Ledger
- YA Bobetsis
- ZA Kaminsky
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2016
- Field of study
Background: In most high and middle income countries across the world, at least 1:4 women give birth by cesarean
section. Rates of labour induction and augmentation are rising steeply; and in some countries up to 50 % of laboring
women and newborns are given antibiotics. Governments and international agencies are increasingly concerned about
the clinical, economic and psychosocial effects of these interventions.
Discussion: There is emerging evidence that certain intrapartum and early neonatal interventions might affect the
neonatal immune response in the longer term, and perhaps trans-generationally. Two theories lead the debate in this
area. Those aligned with the hygiene (or ‘Old Friends’) hypothesis have examined the effect of gut microbiome colonization
secondary to mode of birth and intrapartum/neonatal pharmacological interventions on immune response and epigenetic
phenomena. Those working with the EPIIC (Epigenetic Impact of Childbirth) hypothesis are concerned with the effects of
eustress and dys-stress on the epigenome, secondary to mode of birth and labour interventions.
Summary: This paper examines the current and emerging findings relating to childbirth and atopic/autoimmune
disease from the perspective of both theories, and proposes an alliance of research effort. This is likely to accelerate
the discovery of important findings arising from both approaches, and to maximize the timely understanding of the
longer-term consequences of childbirth practices
CONSORT 2010 statement: extension to randomised pilot and feasibility trials [on behalf of the PAFS consensus group*]
- Author
- A Farrin
- A Hecksteden
- A Leblanc
- A O’Cathain
- A O’Cathain
- A Porserud
- A Tong
- AE Heazell
- AL Whitehead
- B Seebacher
- BC O’Brien
- C Bugge
- C Burton
- C Dyer
- CC Kennedy
- CW Hughes
- D Moher
- D Moher
- D Talmor
- DJ Cook
- DL Burke
- DL Sackett
- DM Arnold
- DT Wilson
- E Crawley
- EA Boogerd
- FC Warren
- FL Hamilton
- G Boysen
- G Piaggio
- GA Lancaster
- GE Vist
- GL Buse
- H Bruhn
- HG Spall Van
- Hip Fracture Accelerated Surgical Treatment and Care Track (HIP ATTACK) Investigators
- I Boutron
- JA Ormiston
- JJ Gagnier
- JL Zisk
- JP Ioannidis
- K Cocks
- K Dickersin
- K Hill
- K Olsen
- KF Schulz
- KM Hill
- L Jackson
- L Thabane
- L Thabane
- L Turner
- L Turner
- LH Thomas
- M Arain
- M Busse
- M Calvert
- M Egger
- M Forero
- M Pai
- M Schoultz
- M Schoultz
- M Schunter
- M Shanyinde
- M Zwarenstein
- MC Ashe
- MD Teare
- ME Cartwright
- MK Campbell
- N Kapur
- N Stallard
- NO Alers
- P Hoddinott
- P Hoddinott
- R Fisch
- R Stow
- RA Begh
- RH Browne
- S Gilbody
- S Hopewell
- S Hopewell
- S Hopewell
- SA Frech
- SA Julious
- SA Stansfeld
- SJ Taylor
- SM Eldridge
- SM Eldridge
- TC Hoffmann
- TR Goldstein
- WF Clark
- World Medical Association declaration of Helsinki
- X Yu
- Z Kmietowicz
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2016
- Field of study
The Consolidated Standards of Reporting Trials (CONSORT) statement is a guideline designed to improve the transparency and quality of the reporting of randomised controlled trials (RCTs). In this article we present an extension to that statement for randomised pilot and feasibility trials conducted in advance of a future definitive RCT. The checklist applies to any randomised study in which a future definitive RCT, or part of it, is conducted on a smaller scale, regardless of its design (eg, cluster, factorial, crossover) or the terms used by authors to describe the study (eg, pilot, feasibility, trial, study). The extension does not directly apply to internal pilot studies built into the design of a main trial, non-randomised pilot and feasibility studies, or phase II studies, but these studies all have some similarities to randomised pilot and feasibility studies and so many of the principles might also apply.
The development of the extension was motivated by the growing number of studies described as feasibility or pilot studies and by research that has identified weaknesses in their reporting and conduct. We followed recommended good practice to develop the extension, including carrying out a Delphi survey, holding a consensus meeting and research team meetings, and piloting the checklist.
The aims and objectives of pilot and feasibility randomised studies differ from those of other randomised trials. Consequently, although much of the information to be reported in these trials is similar to those in randomised controlled trials (RCTs) assessing effectiveness and efficacy, there are some key differences in the type of information and in the appropriate interpretation of standard CONSORT reporting items. We have retained some of the original CONSORT statement items, but most have been adapted, some removed, and new items added. The new items cover how participants were identified and consent obtained; if applicable, the prespecified criteria used to judge whether or how to proceed with a future definitive RCT; if relevant, other important unintended consequences; implications for progression from pilot to future definitive RCT, including any proposed amendments; and ethical approval or approval by a research review committee confirmed with a reference number.
This article includes the 26 item checklist, a separate checklist for the abstract, a template for a CONSORT flowchart for these studies, and an explanation of the changes made and supporting examples. We believe that routine use of this proposed extension to the CONSORT statement will result in improvements in the reporting of pilot trials.
Editor’s note: In order to encourage its wide dissemination this article is freely accessible on the BMJ and Pilot and Feasibility Studies journal websites
Laparoscopy in management of appendicitis in high-, middle-, and low-income countries: a multicenter, prospective, cohort study.
- Author
- Abantanga F
- Abbas M
- Abbo O
- Abd El Galeel A
- Abd El Hameed OS
- Abd El Hamid N
- Abd El Salam Y
- Abd El Slam M
- Abd El-Salam F
- Abd Elrasoul Y
- Abd-Elrasoul Y
- Abdallah E
- Abdel-Wahab NYE
- AbdelFattah I
- Abdelgelil A
- Abdelghany S
- Abdelkader M
- Abdelkareem A
- Abdelraheim M
- Abdelshafy M
- Abdulgawad M
- Abdullah AAN
- Abdullah NAN
- Abebe NS
- Abebe NS
- Aber A
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- Zardab A
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2018
- Field of study
BACKGROUND: Appendicitis is the most common abdominal surgical emergency worldwide. Differences between high- and low-income settings in the availability of laparoscopic appendectomy, alternative management choices, and outcomes are poorly described. The aim was to identify variation in surgical management and outcomes of appendicitis within low-, middle-, and high-Human Development Index (HDI) countries worldwide. METHODS: This is a multicenter, international prospective cohort study. Consecutive sampling of patients undergoing emergency appendectomy over 6 months was conducted. Follow-up lasted 30 days. RESULTS: 4546 patients from 52 countries underwent appendectomy (2499 high-, 1540 middle-, and 507 low-HDI groups). Surgical site infection (SSI) rates were higher in low-HDI (OR 2.57, 95% CI 1.33-4.99, p = 0.005) but not middle-HDI countries (OR 1.38, 95% CI 0.76-2.52, p = 0.291), compared with high-HDI countries after adjustment. A laparoscopic approach was common in high-HDI countries (1693/2499, 67.7%), but infrequent in low-HDI (41/507, 8.1%) and middle-HDI (132/1540, 8.6%) groups. After accounting for case-mix, laparoscopy was still associated with fewer overall complications (OR 0.55, 95% CI 0.42-0.71, p < 0.001) and SSIs (OR 0.22, 95% CI 0.14-0.33, p < 0.001). In propensity-score matched groups within low-/middle-HDI countries, laparoscopy was still associated with fewer overall complications (OR 0.23 95% CI 0.11-0.44) and SSI (OR 0.21 95% CI 0.09-0.45). CONCLUSION: A laparoscopic approach is associated with better outcomes and availability appears to differ by country HDI. Despite the profound clinical, operational, and financial barriers to its widespread introduction, laparoscopy could significantly improve outcomes for patients in low-resource environments. TRIAL REGISTRATION: NCT02179112
Prognostic model to predict postoperative acute kidney injury in patients undergoing major gastrointestinal surgery based on a national prospective observational cohort study.
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- STARSurg Collaborative Writing Committee, Data analysis, Steering committee, Advisory group, Regional leads, Collaborators and validators
- STARSurg Collaborative Writing Committee, Data analysis, Steering committee, Advisory group, Regional leads, Collaborators and validators, Nepogodiev, D
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- Zubikarai G
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- Publication venue
- 'Wiley'
- Publication date
- 18/05/2018
- Field of study
Background: Acute illness, existing co-morbidities and surgical stress response can all contribute to postoperative acute kidney injury (AKI) in patients undergoing major gastrointestinal surgery. The aim of this study was prospectively to develop a pragmatic prognostic model to stratify patients according to risk of developing AKI after major gastrointestinal surgery. Methods: This prospective multicentre cohort study included consecutive adults undergoing elective or emergency gastrointestinal resection, liver resection or stoma reversal in 2-week blocks over a continuous 3-month period. The primary outcome was the rate of AKI within 7 days of surgery. Bootstrap stability was used to select clinically plausible risk factors into the model. Internal model validation was carried out by bootstrap validation. Results: A total of 4544 patients were included across 173 centres in the UK and Ireland. The overall rate of AKI was 14·2 per cent (646 of 4544) and the 30-day mortality rate was 1·8 per cent (84 of 4544). Stage 1 AKI was significantly associated with 30-day mortality (unadjusted odds ratio 7·61, 95 per cent c.i. 4·49 to 12·90; P < 0·001), with increasing odds of death with each AKI stage. Six variables were selected for inclusion in the prognostic model: age, sex, ASA grade, preoperative estimated glomerular filtration rate, planned open surgery and preoperative use of either an angiotensin-converting enzyme inhibitor or an angiotensin receptor blocker. Internal validation demonstrated good model discrimination (c-statistic 0·65). Discussion: Following major gastrointestinal surgery, AKI occurred in one in seven patients. This preoperative prognostic model identified patients at high risk of postoperative AKI. Validation in an independent data set is required to ensure generalizability
Measurement of the cross-section for b-jets produced in association with a Z boson at root s=7 TeV with the ATLAS detector ATLAS Collaboration
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- Wolters H
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- Wooden G
- Wosiek BK
- Wotschack J
- Woudstra MJ
- Wraight K
- Wright C
- Wrona B
- Wu SL
- Wu X
- Wu Y
- Wulf E
- Wunstorf R
- Wynne BM
- Xaplanteris L
- Xella S
- Xie S
- Xie Y
- Xu C
- Xu D
- Xu G
- Yabsley B
- Yacoob S
- Yagci KD
- Yamada M
- Yamaguchi H
- Yamamoto A
- Yamamoto K
- Yamamoto S
- Yamamura T
- Yamanaka T
- Yamaoka J
- Yamazaki T
- Yamazaki Y
- Yan Z
- Yang H
- Yang UK
- Yang Y
- Yang Y
- Yang Z
- Yanush S
- Yao Y
- Yasu Y
- Ye J
- Ye S
- Yildizb HD
- Yilmaz M
- Yoosoofmiya R
- Yorita K
- Yoshida R
- Young C
- Youssef S
- Yu D
- Yu J
- Yu J
- Yuan L
- Yurkewicz A
- Zaets VG
- Zaidan R
- Zaitsev AM
- Zajacova Z
- Zalite YK
- Zanello L
- Zarzhitsky P
- Zaytsev A
- Zeitnitz C
- Zeller M
- Zeman M
- Zemla A
- Zendler C
- Zenin O
- Zenis T
- Zenonos Z
- Zenz S
- Zerwas D
- Zhan Z
- Zhang D
- Zhang H
- Zhang J
- Zhang X
- Zhang Z
- Zhao L
- Zhao T
- Zhao Z
- Zhemchugov A
- Zheng S
- Zhong J
- Zhou B
- Zhou N
- Zhou Y
- Zhu CG
- Zhu H
- Zhu J
- Zhu Y
- Zhuang X
- Zhuravlov V
- Zieminska D
- Zimmermann R
- Zimmermann S
- Zimmermann S
- Ziolkowski M
- Zitoun R
- Zivkovic L
- Zmouchko VV
- Zobernig G
- Zoccoli A
- Zolnierowski Y
- Zsenei A
- zur Nedden M
- Zutshi V
- Zwalinski L
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2011
- Field of study
A measurement is presented of the inclusive cross-section for b-jet production in association with a Z boson in pp collisions at a centre-of-mass energy of root s = 7 TeV. The analysis uses the data sample collected by the ATLAS experiment in 2010, corresponding to an integrated luminosity of approximately 36 pb(-1). The event selection requires a Z boson decaying into high P-T electrons or muons, and at least one b-jet, identified by its displaced vertex, with transverse momentum p(T) > 25 GeV and rapidity vertical bar y vertical bar < 2.1. After subtraction of background processes, the yield is extracted from the vertex mass distribution of the candidate b-jets. The ratio of this cross-section to the inclusive Z cross-section (the average number of b-jets per Z event) is also measured. Both results are found to be in good agreement with perturbative QCD predictions at next-to-leading order
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