Ten golden rules for optimal antibiotic use in hospital settings: the WARNING call to action

Antibiotics are recognized widely for their benefits when used appropriately. However, they are often used inappropriately despite the importance of responsible use within good clinical practice. Effective antibiotic treatment is an essential component of universal healthcare, and it is a global responsibility to ensure appropriate use. Currently, pharmaceutical companies have little incentive to develop new antibiotics due to scientific, regulatory, and financial barriers, further emphasizing the importance of appropriate antibiotic use. To address this issue, the Global Alliance for Infections in Surgery established an international multidisciplinary task force of 295 experts from 115 countries with different backgrounds. The task force developed a position statement called WARNING (Worldwide Antimicrobial Resistance National/International Network Group) aimed at raising awareness of antimicrobial resistance and improving antibiotic prescribing practices worldwide. The statement outlined is 10 axioms, or “golden rules,” for the appropriate use of antibiotics that all healthcare workers should consistently adhere in clinical practice

Ten golden rules for optimal antibiotic use in hospital settings : the WARNING call to action

Abstract: Antibiotics are recognized widely for their benefits when used appropriately. However, they are often used inappropriately despite the importance of responsible use within good clinical practice. Effective antibiotic treatment is an essential component of universal healthcare, and it is a global responsibility to ensure appropriate use. Currently, pharmaceutical companies have little incentive to develop new antibiotics due to scientific, regulatory, and financial barriers, further emphasizing the importance of appropriate antibiotic use. To address this issue, the Global Alliance for Infections in Surgery established an international multidisciplinary task force of 295 experts from 115 countries with different backgrounds. The task force developed a position statement called WARNING (Worldwide Antimicrobial Resistance National/International Network Group) aimed at raising awareness of antimicrobial resistance and improving antibiotic prescribing practices worldwide. The statement outlined is 10 axioms, or "golden rules," for the appropriate use of antibiotics that all healthcare workers should consistently adhere in clinical practice

Infant physical knowledge

Physical reasoning is the ability to go beyond the information in the immediate perceptual array. For example, if I were to dangle my keys in front of me with the intention of letting go of them, everyone would predict that the moment I let go of the keys, they will fall towards the ground. Similarly, if I hide my keys behind my back, everyone has the expectation that the keys continue to exist and that the shape and size of the keys remain the same as they were before they were hidden from view. These two examples demonstrate that people share the same basic ideas about how objects behave and interact. These expectations may be universal across all humans, and they may even be shared by some other species. However, researchers are still puzzled by some aspects of these fundamental abilities. For instance, even though most people can effortlessly draw similar predictions about these events, we have yet to build a computer that can rival the physical reasoning abilities of a typically developing 1-year-old infant. In this chapter, we argue that one way to resolve some of the mysteries about physical reasoning is to look at the origins of the abilities and how they change over time. We start by reviewing the literature on the physical reasoning abilities of human infants. First, we present two case studies: knowledge about objects and knowledge about substances (e.g., liquid, sand, etc.). Each case begins by offering key distinctions that define physical reasoning abilities and then reviews the evidence that support these claims and how these findings provide information about the nature of the representation abilities. The final sections review how these findings relate to neuroscience, sociocultural, and policy perspectives