156 research outputs found

    Examining the Effect of Witnessing Sexual Harassment on School Engagement: The Moderating Role of Gender

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    The following study investigated the potential relationships between directly or indirectly witnessing sexual harassment, the witness’ gender, school engagement, and psychological distress. Participants from an undergraduate university (N = 168) responded to a survey in which they answered questions relating to witnessing sexual harassment and their psychological distress, burnout, school engagement, and perceived social support after the event. For purposes of analyses, potential relationships on psychological distress and school engagement were examined further. Participants who directly witnessed sexual harassment reported lower school engagement than participants who didn’t report directly witnessing sexual harassment. Direct witnesses reported lower levels of vigor, dedication, and absorption to their studies, with indirect witnesses also reporting low absorption. Male participants reported lower levels of psychological distress than female participants regardless of their status as a witness. Given the prevalence of sexual harassment in our culture, more research is needed to fully explore the effects of witnessing it has on people’s mental health and ability to complete their work

    溜池地帯における共同田植と水利 : 兵庫県多紀郡沢田部落における事例的研究

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    textabstractClimbing fibers (CFs) originating in the inferior olive (IO) constitute one of the main inputs to the cerebellum. In the mammalian cerebellar cortex each of them climbs into the dendritic tree of up to ten Purkinje cells where they make hundreds of synaptic contacts and elicit the socalled all-or-none complex spikes controlling the output. While it has been proven that CFs contact molecular layer interneurons (MLIs) via spillover mechanisms, it remains to be elucidated to what extent CFs contact the main type of interneuron in the granular layer, i.e. the Golgi cells (GoCs). This issue is particularly relevant, because direct contacts would imply that CFs can also control computations at the input stage of the cerebellar cortical network. Here, we performed a systematic morphological investigation of labeled CFs and GoCs at the light microscopic level following their path and localization through the neuropil in both the granular and molecular layer. Whereas the appositions of CFs to Purkinje cells, stellate cells and basket cells in the molecular layer were prominent and numerous, those to cell-bodies and dendrites of GoCs in both the granular layer and molecular layer were virtually absent. Our results argue against the functional significance of direct synaptic contacts between CFs and interneurons at the input stage, but support those at the output stage

    Infância, exclusão social e educação como utopia realizável

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    A infância, como construção social, tem sofrido, no decurso da 2ª modernidade, processos de reinstitucionalização que, em larga medida, põem em causa as representações e imagens das crianças, dominantes nos últimos 200 anos. A análise da (re)construção das identidades sociais e das subjectividades infantis constitui, desse modo, uma tarefa teórica da mais exigente actualidade. O que, entretanto, aqui se assinala é que este processo de reinstitucionalização da infância, apesar da construção de consensos globais sobre os direitos das crianças, tem vindo a aumentar os factores e as condições de exclusão das gerações mais jovens face aos direitos sociais e da cidadania. Neste artigo inventariam-se alguns dos principais indicadores de exclusão, considerando diversos espaços estruturais, e assinalam-se alguns dos pontos de ruptura por onde pode passar a construção de uma educação escolar centrada na afirmação activa dos direitos das crianças.Along the second modernity, childhood, as a social construction, has undergone reinstatement processes that question the representations and images of children that have prevailed over last two hundred years. An analysis of the (re) construction of the social identities and childhood subjectivity thus constitute a theoretical task of the most contemporary exigence. Nevertheless, even though a global consensus about children’s rights has been constructed, the increase of factors and conditions that exclude the youngest generations from social rights and citizenship, induced by this reinstatement process of childhood, is here emphasized. This paper lists some of the main indicators of exclusion, considering different structural spaces, and pinpoints some turning points through which the construction of a school education centered on the active affirmation of the children’s rights could be attained.CIFPEC/CIEC - Centro de Investigação em Estudos da Criança, UM (UI 644 e 317 da FCT

    Cortical Gray Matter Injury in Encephalopathy of Prematurity: Link to Neurodevelopmental Disorders

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    Preterm-born infants frequently suffer from an array of neurological damage, collectively termed encephalopathy of prematurity (EoP). They also have an increased risk of presenting with a neurodevelopmental disorder (e.g., autism spectrum disorder; attention deficit hyperactivity disorder) later in life. It is hypothesized that it is the gray matter injury to the cortex, in addition to white matter injury, in EoP that is responsible for the altered behavior and cognition in these individuals. However, although it is established that gray matter injury occurs in infants following preterm birth, the exact nature of these changes is not fully elucidated. Here we will review the current state of knowledge in this field, amalgamating data from both clinical and preclinical studies. This will be placed in the context of normal processes of developmental biology and the known pathophysiology of neurodevelopmental disorders. Novel diagnostic and therapeutic tactics required integration of this information so that in the future we can combine mechanism-based approaches with patient stratification to ensure the most efficacious and cost-effective clinical practice

    Half a century of amyloids: past, present and future

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    Amyloid diseases are global epidemics with profound health, social and economic implications and yet remain without a cure. This dire situation calls for research into the origin and pathological manifestations of amyloidosis to stimulate continued development of new therapeutics. In basic science and engineering, the cross-ß architecture has been a constant thread underlying the structural characteristics of pathological and functional amyloids, and realizing that amyloid structures can be both pathological and functional in nature has fuelled innovations in artificial amyloids, whose use today ranges from water purification to 3D printing. At the conclusion of a half century since Eanes and Glenner's seminal study of amyloids in humans, this review commemorates the occasion by documenting the major milestones in amyloid research to date, from the perspectives of structural biology, biophysics, medicine, microbiology, engineering and nanotechnology. We also discuss new challenges and opportunities to drive this interdisciplinary field moving forward. This journal i

    Cittadinanze impari

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    Examining the Effect of Witnessing Sexual Harassment on School Engagement: The Moderating Role of Gender

    No full text
    The following study investigated the potential relationships between directly or indirectly witnessing sexual harassment, the witness’ gender, school engagement, and psychological distress. Participants from an undergraduate university (N = 168) responded to a survey in which they answered questions relating to witnessing sexual harassment and their psychological distress, burnout, school engagement, and perceived social support after the event. For purposes of analyses, potential relationships on psychological distress and school engagement were examined further. Participants who directly witnessed sexual harassment reported lower school engagement than participants who didn’t report directly witnessing sexual harassment. Direct witnesses reported lower levels of vigor, dedication, and absorption to their studies, with indirect witnesses also reporting low absorption. Male participants reported lower levels of psychological distress than female participants regardless of their status as a witness. Given the prevalence of sexual harassment in our culture, more research is needed to fully explore the effects of witnessing it has on people’s mental health and ability to complete their work
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