Search for dark matter in events with heavy quarks and missing transverse momentum in pp collisions with the ATLAS detector

This article reports on a search for dark matterpair production in association with bottom or top quarks in20.3fb−1ofppcollisions collected at√s=8TeVbytheATLAS detector at the LHC. Events with large missing trans-verse momentum are selected when produced in associationwith high-momentum jets of which one or more are identifiedas jets containingb-quarks. Final states with top quarks areselected by requiring a high jet multiplicity and in some casesa single lepton. The data are found to be consistent with theStandard Model expectations and limits are set on the massscale of effective field theories that describe scalar and tensorinteractions between dark matter and Standard Model par-ticles. Limits on the dark-matter–nucleon cross-section forspin-independent and spin-dependent interactions are alsoprovided. These limits are particularly strong for low-massdark matter. Using a simplified model, constraints are set onthe mass of dark matter and of a coloured mediator suitableto explain a possible signal of annihilating dark matter

Search for direct production of charginos and neutralinos in events with three leptons and missing transverse momentum in √s = 8 TeV pp collisions with the ATLAS detector

A search for the direct production of charginos and neutralinos in final states with three leptons and missing transverse momentum is presented. The analysis is based on 20.3 fb−1 of s√ = 8 TeV proton-proton collision data delivered by the Large Hadron Collider and recorded with the ATLAS detector. Observations are consistent with the Standard Model expectations and limits are set in R-parity-conserving phenomenological Minimal Supersymmetric Standard Models and in simplified supersymmetric models, significantly extending previous results. For simplified supersymmetric models of direct chargino (χ˜±1) and next-to-lightest neutralino (χ˜02) production with decays to lightest neutralino (χ˜01) via either all three generations of sleptons, staus only, gauge bosons, or Higgs bosons, (χ˜±1) and (χ˜02) masses are excluded up to 700 GeV, 380 GeV, 345 GeV, or 148 GeV respectively, for a massless (χ˜01

European Heart Rhythm Association (EHRA)/Heart Rhythm Society (HRS)/Asia Pacific Heart Rhythm Society (APHRS)/Latin American Heart Rhythm Society (LAHRS) expert consensus on arrhythmias and cognitive function::what is the best practice?

Publicado também em: https://repositorio.unifesp.br/handle/11600/45988Heart Ctr Leipzig, Dept Electrophysiol, Leipzig, GermanyTaipei Vet Gen Hosp, Taipei, TaiwanHosp Israelita Albert Einstein, Sao Paulo, BrazilCtr Privado Cardiol, San Miguel De Tucuman, ArgentinaMem Hlth, Cardiac & Vasc Inst, Hollywood, FL USABoston Univ, Sch Med, Framingham Heart Study, Boston, MA 02118 USABoston Univ, Sch Publ Hlth, Framingham Heart Study, Boston, MA 02118 USAIntermt Med Ctr, Murray, UT USAUniv Minnesota, Dept Med, Cardiovasc Div, Minneapolis, MN USAUniv Sao Paulo, Med Sch, Sao Paulo, BrazilUniv Fed Sao Paulo, Escola Paulista Med, Sao Paulo, BrazilUniv Tours, Ctr Hosp Univ Trousseau, Serv Cardiol, Tours, FranceUniv Hosp Magdeburg, St Vincenz Hosp Paderborn, Working Grp Mol Electrophysiol, Dept Cardiol & Intens Care Med, Magdeburg, GermanyUniv Melbourne, Royal Melbourne Hosp, Melbourne, Vic, AustraliaKings Coll London, London, EnglandKorea Univ, Med Ctr, Seoul, South KoreaUniv Birmingham, Inst Cardiovasc Sci, Birmingham, W Midlands, EnglandAalborg Univ, Dept Clin Med, Aalborg Thrombosis Res Unit, Aalborg, DenmarkMassachusetts Gen Hosp, Boston, MA 02114 USAInst Nacl Cardiol, Dept Electrocardiog, Mexico City, DF, MexicoUniv Belgrade, Sch Med, Belgrade, SerbiaClin Ctr Serbia, Cardiol Clin, Belgrade, SerbiaInst Cardiol Corrientes, Corrientes, ArgentinaSt Georges Univ London, Cardiol Clin Acad Grp, Mol & Clin Sci Res Inst, London, EnglandNatl Heart Ctr, Singapore, SingaporeUniv Hong Kong, Dept Med, Hong Kong, Hong Kong, Peoples R ChinaSouthlake Reg Hlth Ctr, Newmarket, ON, CanadaBeijing Fuwai Hosp, Beijing, Peoples R ChinaCleveland Clin, Cleveland, OH 44106 USAUniv Fed Sao Paulo, Escola Paulista Med, Sao Paulo, BrazilWeb of Scienc

A first update on mapping the human genetic architecture of COVID-19

peer reviewe

Metacognitive impairments extend perceptual decision making weaknesses in compulsivity

AbstractAwareness of one’s own abilities is of paramount importance in adaptive decision making. Psychotherapeutic theories assume such metacognitive insight is impaired in compulsivity, though this is supported by scant empirical evidence. In this study, we investigate metacognitive abilities in compulsive participants using computational models, where these enable a segregation between metacognitive and perceptual decision making impairments. We examined twenty low-compulsive and twenty high-compulsive participants, recruited from a large population-based sample, and matched for other psychiatric and cognitive dimensions. Hierarchical computational modelling of the participants’ metacognitive abilities on a visual global motion detection paradigm revealed that high-compulsive participants had a reduced metacognitive ability. This impairment was accompanied by a perceptual decision making deficit whereby motion-related evidence was accumulated more slowly in high compulsive participants. Our study shows that the compulsivity spectrum is associated with a reduced ability to monitor one’s own performance, over and above any perceptual decision making difficulties.</jats:p

Measurements of the νμ\nu_{\mu} and νˉμ\bar{\nu}_{\mu}-induced Coherent Charged Pion Production Cross Sections on 12C^{12}C by the T2K experiment

We report an updated measurement of the $\nu_{\mu}$-induced, and the first measurement of the $\bar{\nu}_{\mu}$-induced coherent charged pion production cross section on $^{12}C$ nuclei in the T2K experiment. This is measured in a restricted region of the final-state phase space for which $p_{\mu,\pi} > 0.2$ GeV, $\cos(\theta_{\mu}) > 0.8$ and $\cos(\theta_{\pi}) > 0.6$, and at a mean (anti)neutrino energy of 0.85 GeV using the T2K near detector. The measured $\nu_{\mu}$ CC coherent pion production flux-averaged cross section on $^{12}C$ is $(2.98 \pm 0.37 (stat.) \pm 0.31 (syst.) \substack{ +0.49 \\ -0.00 } \mathrm{ (Q^2\,model)}) \times 10^{-40}~\mathrm{cm}^{2}$. The new measurement of the $\bar{\nu}_{\mu}$-induced cross section on $^{12}{C}$ is $(3.05 \pm 0.71 (stat.) \pm 0.39 (syst.) \substack{ +0.74 \\ -0.00 } \mathrm{(Q^2\,model)}) \times 10^{-40}~\mathrm{cm}^{2}$. The results are compatible with both the NEUT 5.4.0 Berger-Sehgal (2009) and GENIE 2.8.0 Rein-Sehgal (2007) model predictions

SARS-CoV-2 susceptibility and COVID-19 disease severity are associated with genetic variants affecting gene expression in a variety of tissues

Variability in SARS-CoV-2 susceptibility and COVID-19 disease severity between individuals is partly due to genetic factors. Here, we identify 4 genomic loci with suggestive associations for SARS-CoV-2 susceptibility and 19 for COVID-19 disease severity. Four of these 23 loci likely have an ethnicity-specific component. Genome-wide association study (GWAS) signals in 11 loci colocalize with expression quantitative trait loci (eQTLs) associated with the expression of 20 genes in 62 tissues/cell types (range: 1:43 tissues/gene), including lung, brain, heart, muscle, and skin as well as the digestive system and immune system. We perform genetic fine mapping to compute 99% credible SNP sets, which identify 10 GWAS loci that have eight or fewer SNPs in the credible set, including three loci with one single likely causal SNP. Our study suggests that the diverse symptoms and disease severity of COVID-19 observed between individuals is associated with variants across the genome, affecting gene expression levels in a wide variety of tissue types

Measurement of the production of a W boson in association with a charm quark in pp collisions at √s = 7 TeV with the ATLAS detector

The production of a W boson in association with a single charm quark is studied using 4.6 fb−1 of ppcollision data at √s= 7 TeV collected with the ATLAS detector at the Large Hadron Collider. In events in which a Wboson decays to an electron or muon, the charm quark is tagged either by its semileptonic decay to a muon or by the presence of a charmed meson. The integrated and differential cross sections as a function of the pseudorapidity of the lepton from the W-boson decay are measured. Results are compared to the predictions of next-to-leading-order QCD calculations obtained from various parton distribution function parameterisations. The ratio of the strange-to-down sea-quark distributions is determined to be0.96+0.26−0.30at Q 2 = 1.9 GeV2, which supports the hypothesis of an SU(3)-symmetric composition of the light-quark sea. Additionally, the cross-section ratio σ(W + +c¯)/σ(W − + c) is compared to the predictions obtained using parton distribution function parameterisations with different assumptions about thes−s¯quark asymmetry

Search for pair-produced massive coloured scalars in four-jet final states with the ATLAS detector in proton-proton collisions at s=7\sqrt{s}=7 TeV

A search for pair-produced massive coloured scalar particles decaying to a four-jet final state is performed by the ATLAS experiment at the LHC in proton-proton collisions at sqrt(s) = 7 TeV. The analysed data sample corresponds to an integrated luminosity of 4.6 /fb. No deviation from the Standard Model is observed in the invariant mass spectrum of the two-jet pairs. A limit on the scalar gluon pair production cross-section of 70 pb (10 pb) is obtained at the 95% confidence level for a scalar gluon mass of 150 GeV (350 GeV). Interpreting these results as mass limits on scalar gluons, masses ranging from 150 GeV to 287 GeV are excluded at the 95% confidence level

Search for high-mass resonances decaying to dilepton final states in pp collisions at root s=7 TeV with the ATLAS detector

The ATLAS detector at the Large Hadron Collider is used to search for high-mass resonances decaying to an electron-positron pair or a muon-antimuon pair. The search is sensitive to heavy neutral Z' gauge bosons, Randall-Sundrum gravitons, Z* bosons, techni-mesons, Z/gamma bosons, and bosons predicted by Torsion models. Results are presented based on an analysis of pp collisions at a center-of-mass energy of 7 TeV corresponding to an integrated luminosity of 4.9 fb(-1) in the e(+)e(-) channel and 5.0 fb(-1) in the mu(+)mu(-) channel. A Z' boson with Standard Model-like couplings is excluded at 95% confidence level for masses below 2.22 TeV. A Randall-Sundrum graviton with coupling k root M-P1 = 0.1 is excluded at 95% confidence level for masses below 2.16 Tev. Limits on the other models are also presented, including Technicolor and Minimal Z' Models.We acknowledge the support of ANPCyT, Argentina; YerPhI, Armenia; ARC, Australia; BMWF, Austria: ANAS, Azerbaijan; SSTC, Belarus: CNPq and FAPESP, Brazil; NSERC, NRC and CFI, Canada; CERN; CONICYT, Chile; CAS, MOST and NSFC, China: COLCIENCIAS, Colombia; MSMT CR, MPO CR and VSC CR, Czech Republic; DNRF, DNSRC and Lundbeck Foundation, Denmark; EPLANET and ERC, European Union; IN2P3-CNRS, CFA-OSM/IRFU, Frame; GNAS, Georgia; BMBF, DFG, MPG and AvH Foundation, Germany; GSRT, Greece; ISF, MINERVA, CIF, DIP and Benoziyo Center, Israel; INFN, Italy; MEXT and JSPS, Japan; CNRST, Morocco; FOM and NWO, Netherlands; RCN, Norway; MNiSW, Poland; GRICES and FCT, Portugal;,MERYS (MECTS), Romania; MES of Russia and ROSATOM, Russian Federation; JINR; MSTD, Serbia; MSSR, Slovakia; ARRS and MVZT, Slovenia; DST/NRF, South Africa; MICINN, Spain; SRC and Wallenberg Foundation, Sweden; SFR, SNSF and Cantons of Bern and Geneva, Switzerland; NSC, Taiwan; TAEK, Turkey; STFC, the Royal Society and Leverhulme Trust, United Kingdom; DOE and NSF, United States of America.info:eu-repo/semantics/publishedVersio